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https://www.readbyqxmd.com/read/29332032/value-of-conventional-mri-and-diffusion-tensor-imaging-parameters-in-predicting-surgical-outcome-in-patients-with-degenerative-cervical-myelopathy
#1
Canghai Shen, Haiwei Xu, Baoshan Xu, Xiaoguang Zhang, Xiaofeng Li, Qiang Yang, Xinlong Ma
BACKGROUND: In addition to conventional magnetic resonance imaging (cMRI), diffusion tensor imaging (DTI) has been investigated as a potential diagnostic and prognostic tool for patients with degenerative cervical myelopathy (DCM). OBJECTIVE: To assess the efficacy of cMRI and DTI parameters in prediction of surgical outcome in DCM patients. METHODS: One hundred and forty-two patients with DCM who underwent presurgical cMRI and DTI of the cervical spine were included...
December 29, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/29330570/open-door-laminoplasty-what-can-the-unilateral-approach-offer
#2
REVIEW
R Kothe, G Schmeiser, L Papavero
OBJECTIVE: Multilevel posterior decompression of subaxial cervical spinal canal stenosis through a less-invasive unilateral approach. INDICATIONS: Degenerative cervical myelopathy due to multilevel subaxial spinal canal stenosis. CONTRAINDICATIONS: Cervical kyphosis or instability, bilateral radiculopathy due to foraminal stenosis, involvement of C2 or C7. SURGICAL TECHNIQUE: Unilateral subaxial approach with detachment of muscles only on one side...
January 12, 2018: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/29328996/acute-and-sub-acute-neurological-toxicity-in-children-treated-for-acute-lymphoblastic-leukemia
#3
REVIEW
Natalia C Millan, Analía Pastrana, Myriam R Guitter, Pedro A Zubizarreta, María S Monges, María S Felice
Eighty percent of children with acute lymphoblastic leukemia (ALL) survive with current treatments. Neurotoxicity is an infrequent adverse event. We describe clinical presentations of neurological toxicity, phases of treatment when these adverse events were more frequent and patients ́ outcome. From January-1995 to December-2015, 1379 ALL cases were admitted. Neurotoxicity was diagnosed in 49 patients (3.6%) and classified according to neurological syndromes. Medical records, laboratory-tests and images were reviewed...
January 2, 2018: Leukemia Research
https://www.readbyqxmd.com/read/29327555/-anterior-versus-posterior-approach-for-multilevel-cervical-spondylotic-myelopathy-a-meta-analysis
#4
Jing-Yang You, Yong Zheng, Ming Chen, Jiang-Rong Fan
OBJECTIVE: To assess the clinical effectiveness and safety of anterior versus posterior approach for multilevel cervical spondylotic myelopathy. METHODS: The following databases were searched: the Cochrane Library, PubMed, EM base, OVID, CBM, Wanfang Data, CNKI. Relevant journals were manually searched for randomized controlled trials or clinical controlled trials(CCTs) that investigated the clinical effectiveness and safety of anterior and posterior approach for multilevel cervical spondylotic myelopathy...
January 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29326877/natural-history-of-morquio-a-patient-with-tracheal-obstruction-from-birth-to-death
#5
Caitlin Doherty, Lauren W Averill, Mary Theroux, William G Mackenzie, Christian Pizarro, Robert W Mason, Shunji Tomatsu
Morquio A syndrome (mucopolysaccharidosis IVA, MPS IVA) is a lysosomal storage disease caused by a deficiency of N-acetylgalactosamine-6-sulfate sulfatase, resulting in systemic accumulation of the partially degraded glycosaminoglycans (GAGs), keratan sulfate and chondroitin-6-sulfate. The accumulation of these GAGs leads to distinguishing features as skeletal dysplasia with disproportionate dwarfism, short neck, kyphoscoliosis, pectus carinatum, tracheal obstruction, coxa valga, genu valgum, and joint laxity...
March 2018: Molecular Genetics and Metabolism Reports
https://www.readbyqxmd.com/read/29325956/rapid-onset-thoracic-myelopathy-due-to-an-epidural-sarcoid-like-lesion-in-a-pediatric-patient
#6
Michael A Galgano, Carlos R Goulart, Karen Chisholm, Melissa Hazen, Scellig Stone
Isolated intraspinal neurosarcoidosis is a rare clinical entity, with most reports describing intramedullary involvement in adults. We detail the case of a nine-year-old girl with rapid onset compressive myelopathy secondary to a thoracic epidural lesion. Although pathological diagnosis was challenging, a presumptive diagnosis of isolated extradural neurosarcoidosis was made in light of the patient's investigations and dramatic response to corticosteroids. Though less likely than neoplasia, rheumatologic processes such as inflammatory granulomatous disease warrant consideration in similar cases...
January 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29325950/a-novel-technique-for-cervical-laminoplasty-fusion-clpf-simultaneously-enhancing-stabilization-and-decompression-in-various-cervical-myelopathies-a-technical-note-and-outcomes
#7
Il Sup Kim, Jae Taek Hong, Jung Jae Lee, Jong Bum Lee, Chul Bum Cho, Seung Ho Yang, Jae Hoon Sung
PURPOSE: Cervical laminectomy has two major disadvantages: post-laminectomy adhesion of dural membrane and the lack of a fusion bed. The objective of this study was to determine whether simultaneous laminoplasty with fusion (CLPF) might overcome these unwanted outcomes. METHODS: Cases of CLPF for treating various cervical myelopathy with instability who were followed up for at least 12 months were enrolled. Preoperative and postoperative Neck Disability Index (NDI), Japanese Orthopedic Association (JOA) scores before and after surgeries, recovery rates (RRs), C2-7 lordosis, and fusion success rates were evaluated...
January 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29325596/late-normal-tissue-response-in-the-rat-spinal-cord-after-carbon-ion-irradiation
#8
Maria Saager, Peter Peschke, Thomas Welzel, Lifi Huang, Stephan Brons, Rebecca Grün, Michael Scholz, Jürgen Debus, Christian P Karger
BACKGROUND: The present work summarizes the research activities on radiation-induced late effects in the rat spinal cord carried out within the "clinical research group ion beam therapy" funded by the German Research Foundation (DFG, KFO 214). METHODS AND MATERIALS: Dose-response curves for the endpoint radiation-induced myelopathy were determined at 6 different positions (LET 16-99 keV/μm) within a 6 cm spread-out Bragg peak using either 1, 2 or 6 fractions of carbon ions...
January 11, 2018: Radiation Oncology
https://www.readbyqxmd.com/read/29325524/posterior-decompression-and-occipitocervical-fixation-followed-by-intraoperative-vertebroplasty-for-metastatic-involvement-of-the-axis
#9
Xinjie Wu, Mingsheng Tan, Yingna Qi, Ping Yi, Feng Yang, Xiangsheng Tang, Qingying Hao
BACKGROUND: Metastases to the upper cervical spine were rarely reported in the literature. However, metastases to this area may cause spinal instability and cord compression, which in turn can result in respiratory failure and neurological dysfunction. The present study investigated the efficacy and safety of posterior decompression and occipitocervical fixation followed by intraoperative vertebroplasty for this disease. METHODS: This was a retrospective study that included 10 patients with metastatic involvement of the axis from March 2002 to May 2014...
January 11, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29322962/etiologic-spectrum-and-prognosis-in-noncompressive-acute-transverse-myelopathies-an-experience-of-80-patients-at-a-tertiary-care-facility
#10
Shuchit Pandey, Ravindra K Garg, Hardeep S Malhotra, Amita Jain, Kiran P Malhotra, Neeraj Kumar, Rajesh Verma, Praveen K Sharma
INTRODUCTION: We evaluated the spectrum of acquired demyelinating and inflammatory disorders in patients presenting with an acute transverse myelopathy. We also studied differences between an acute idiopathic transverse myelitis and myelitis resulting from other etiologies. MATERIALS AND METHODS: Eighty consecutive patients with acute transverse myelopathy were included. At inclusion, clinical profile, serum and cerebrospinal fluid parameters, brain and spinal cord magnetic resonance imaging, and visual evoked potentials were obtained...
January 2018: Neurology India
https://www.readbyqxmd.com/read/29322309/the-global-spine-care-initiative-a-summary-of-guidelines-on-invasive-interventions-for-the-management-of-persistent-and-disabling-spinal-pain-in-low-and-middle-income-communities
#11
REVIEW
Emre Acaroğlu, Margareta Nordin, Kristi Randhawa, Roger Chou, Pierre Côté, Tiro Mmopelwa, Scott Haldeman
PURPOSE: The purpose of this study was to synthesize recommendations on the use of common elective surgical and interventional procedures for individuals with persistent and disabling non-radicular/axial with or without myelopathy, radicular back pain, cervical myelopathy, symptomatic spinal stenosis, and fractures due to osteoporosis. This review was to inform a clinical care pathway on the patient presentations where surgical interventions could reasonably be considered. METHODS: We synthesized recommendations from six evidence-based clinical practice guidelines and one appropriate use criteria guidance for the surgical and interventional management of persistent and disabling spine pain...
January 10, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29318453/sensory-neuronopathy-heralding-human-t-cell-lymphotropic-virus-type-i-myelopathy
#12
Alberto R M Martinez, Raphael F Casseb, Carlos R Martins, Anamarli Nucci, Marcondes C França
Neurological phenotypes of human T cell lymphotropic virus type I (HTLV-1) are numerous and rarely may not manifest the classic HTLV-associated myelopathy/tropical spastic paraparesis (HAM/TSP). We report a case of HTLV-1-related sensory neuronopathy heralding the classic HAM/TSP.
January 9, 2018: Journal of Neurovirology
https://www.readbyqxmd.com/read/29318337/full-endoscopic-posterior-foraminotomy-surgery-for-cervical-disc-herniations
#13
REVIEW
M Komp, S Oezdemir, P Hahn, S Ruetten
OBJECTIVE: Surgery for cervical disc herniation with full-endoscopic posterior access. INDICATIONS: Cervical disc herniation and neuroforaminal pathology with radicular symptoms. CONTRAINDICATIONS: Neck pain alone, cervical myelopathy or pathologies with central nervous system symptoms, instabilities requiring correction/instabilities. SURGICAL TECHNIQUE: Introduction of a surgical tube to the facet joint at the level to be operated on...
January 9, 2018: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/29318336/-decompression-for-cervical-disc-herniation-using-the-full-endoscopic-anterior-technique-german-version
#14
REVIEW
S Oezdemir, M Komp, P Hahn, S Ruetten
OBJECTIVE: Resection of a cervical disc herniation using a full-endoscopic technique with an anterior approach. INDICATION: Fresh disc herniation with monoradicular symptoms in the upper extremity. CONTRAINDICATIONS: Pure neck pain, cervical myelopathy, older and calcified disc herniations, higher grade of instability and deformity. SURGICAL TECHNIQUE: Introduction of a guidewire and dilatator to a cervical disc using an anterior approach...
January 9, 2018: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/29315121/cervical-total-disk-arthroplasty
#15
Timothy T Roberts, Ryan J Filler, Jason W Savage, Edward C Benzel
In the United States, cervical total disk arthroplasty (TDA) is US Federal Drug Administration (FDA) approved for use in both 1 and 2-level constructions for cervical disk disease resulting in myelopathy and/or radiculopathy. TDA designs vary in form, function, material composition, and even performance in vivo. However, the therapeutic goals are the same: to remove the painful degenerative/damaged elements of the intervertebral discoligamenous joint complex, to preserve or restore the natural range of spinal motion, and to mitigate stresses on adjacent spinal segments, thereby theoretically limiting adjacent segment disease (ASDis)...
January 8, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29309979/microsurgical-and-endovascular-treatments-of-spinal-extradural-arteriovenous-fistulas-with-or-without-intradural-venous-drainage
#16
Keisuke Takai, Masaaki Shojima, Hideaki Imai, Nobuhito Saito, Makoto Taniguchi
BACKGROUND: Limited information is available on spinal extradural arteriovenous fistulas (AVFs). OBJECTIVE: To present treatment strategies in relation to the angioarchitecture. METHODS: Fourteen patients treated at 2 hospitals were retrospectively analyzed. RESULTS: Fourteen AVFs included 4 cervical, 1 thoracic, and 9 lumbosacral lesions. Three key angiographic features were observed: 1) the feeding artery, 2) an enlarged extradural venous plexus, and 3) intradural retrograde venous drainage...
January 5, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29303468/validation-of-patient-reported-outcomes-measurement-information-system-promis-computerized-adaptive-tests-in-cervical-spine-surgery
#17
Barrett S Boody, Surabhi Bhatt, Aditya S Mazmudar, Wellington K Hsu, Nan E Rothrock, Alpesh A Patel
OBJECTIVE The Patient-Reported Outcomes Measurement Information System (PROMIS), which is funded by the National Institutes of Health, is a set of adaptive, responsive assessment tools that measures patient-reported health status. PROMIS measures have not been validated for surgical patients with cervical spine disorders. The objective of this project is to evaluate the validity (e.g., convergent validity, known-groups validity, responsiveness to change) of PROMIS computer adaptive tests (CATs) for pain behavior, pain interference, and physical function in patients undergoing cervical spine surgery...
January 5, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29300252/a-follow-up-study-of-postoperative-dcm-patients-using-diffusion-mri-with-dti-and-noddi
#18
Xiaodong Ma, Xiao Han, Wen Jiang, Jinchao Wang, Zhe Zhang, Guangqi Li, Jieying Zhang, Xiaoguang Cheng, Huijun Chen, Hua Guo, Wei Tian
STUDY DESIGN: A retrospective cohort study. OBJECTIVE: To investigate the relationship between spinal cord microstructures and spinal cord dysfunction in degenerative cervical myelopathy (DCM) patients, a follow-up study was carried out using diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI), an advanced diffusion model. SUMMARY OF BACKGROUND DATA: DTI has been used for diagnosis of DCM. Though DTI has advantages of high sensitivity and quantitative features, it is limited by its low specificity for measuring microstructures...
January 3, 2018: Spine
https://www.readbyqxmd.com/read/29285560/anterior-controllable-antidisplacement-and-fusion-surgery-for-the-treatment-of-multilevel-severe-ossification-of-the-posterior-longitudinal-ligament-with-myelopathy-preliminary-clinical-results-of-a-novel-technique
#19
Jingchuan Sun, Jiangang Shi, Ximing Xu, Yong Yang, Yuan Wang, Qingjie Kong, Haisong Yang, Yongfei Guo, Dan Han, Jingjing Jiang, Guodong Shi, Wen Yuan, Lianshun Jia
PURPOSE: Although anterior and posterior decompression surgery are both reported to treat patients with myelopathy caused by ossification of the posterior longitudinal ligament (OPLL). The surgical strategy of the disease is still controversial when the OPLL is multilevel and severe. This present study reports the preliminary clinical results of a novel technique named anterior controllable antidisplacement and fusion (ACAF) for the treatment of multilevel-severe OPLL with myelopathy...
December 28, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29284641/cervical-radiculopathy-and-cervical-myelopathy-diagnosis-and-management-in-primary-care
#20
Sarah McCartney, Richard Baskerville, Stuart Blagg, David McCartney
No abstract text is available yet for this article.
January 2018: British Journal of General Practice: the Journal of the Royal College of General Practitioners
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