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Asthma, spirometry in children

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https://www.readbyqxmd.com/read/29449165/spirometry-and-impulse-oscillometry-in-preschool-children-acceptability-and-relationship-to-maternal-smoking-in-pregnancy
#1
Meyer Kattan, Leonard B Bacharier, George T O'Connor, Robyn Cohen, Ronald L Sorkness, Wayne Morgan, Peter J Gergen, Katy F Jaffee, Cynthia M Visness, Robert A Wood, Gordon R Bloomberg, Susan Doyle, Ryan Burton, James E Gern
BACKGROUND: Comparisons of the technical acceptability of spirometry and impulse oscillometry (IOS) and clinical correlations of the measurements have not been well studied in young children. There are no large studies focused on African American and Hispanic children. OBJECTIVES: We sought to (1) compare the acceptability of spirometry and IOS in 3- to 5-year-old children and (2) examine the relationship of maternal smoking during pregnancy to later lung function...
February 13, 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29427984/controlling-the-risk-domain-in-pediatric-asthma-through-personalized-care
#2
William C Anderson, Stanley J Szefler
Strategies to control the risk domain of NHLBI EPR-3 (National Heart, Lung, and Blood Institute Expert Panel Report-3) asthma guidelines, which includes exacerbations requiring systemic corticosteroids, reduction in lung growth, and progressive loss of lung function, and treatment-related adverse effects, are evolving in children and adolescents. Increasing evidence demonstrates that children and adolescents with asthma are at risk of a reduction in lung growth, leading to lower lung function and potentially chronic obstructive pulmonary disease as adults...
February 2018: Seminars in Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29422824/the-relationship-between-body-mass-index-and-increased-airway-reactivity-based-on-methacholine-challenge-test-results
#3
Maryam Haddadzadeh Shoshtari, Hossein Tahmasbian Malayeri, Hadi Shahrad Bejestani
Introduction: According to the reports of the United States National Bureau of Statistics regarding the prevalence of obesity among adults and children and also asthma outbreak, the relationship between asthma and obesity in developed countries is taken into consideration. Aim: Relationship between body mass index and increased airway reactivity based on methacholine challenge test results. Material and methods: It was a retrospective cross-sectional study done on 256 patients who were referred to the lung clinic of the Imam Khomeini Hospital of Ahvaz with symptoms of hypersensitivity of the airways...
December 2017: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29412429/association-between-fraction-of-exhaled-nitric-oxide-and-spirometry-data-and-clinical-control-of-asthma-in-children-and-adolescents
#4
Luanda Dias da Silva Salviano, Karla Delevedove Taglia-Ferre, Sandra Lisboa, Ana Carolina Carioca da Costa, Hisbello da Silva Campos, Maria de Fátima Pombo March
OBJECTIVE: To evaluate the association between fraction of exhaled nitric oxide (FeNO) values and forced expiratory volume in the first second (FEV1) and the level of asthma control, as proposed by the Global Initiative for Asthma (GINA), in asthmatic children and adolescents attended at the National Institute of Women, Children and Adolescents Health Fernandes Figueira of Fundação Oswaldo Cruz (IFF/FIOCRUZ). METHODS: This was a cross-sectional study, with a review of medical records of 90 asthmatics between 7 and 17 years old, who were followed up at the IFF/FIOCRUZ Asthma Outpatient Clinic and were referred to perform respiratory function tests (RFT)between March 2013 and September 2014...
January 15, 2018: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/29405616/flow-volume-loops-measured-with-electrical-impedance-tomography-in-pediatric-patients-with-asthma
#5
Chuong Ngo, Falk Dippel, Klaus Tenbrock, Steffen Leonhardt, Sylvia Lehmann
BACKGROUND: Electrical impedance tomography (EIT) provides information on global and regional ventilation during tidal breathing and mechanical ventilation. During forced expiration maneuvers, the linearity of EIT and spirometric data has been documented in healthy persons. The present study investigates the potential diagnostic use of EIT in pediatric patients with asthma. METHODS: EIT and spirometry were performed in 58 children with asthma (average age ± SD: 11...
February 6, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29401500/mobile-direct-observation-of-therapy-mdot-a-rapid-systematic-review-and-pilot-study-in-children-with-asthma
#6
Michael D Shields, Fahad ALQahtani, Michael P Rivey, James C McElnay
We describe, for the first time, the use of a mobile device platform for remote direct observation of inhaler use and technique. The research programme commenced with a rapid systematic review of mobile device (or videophone) use for direct observation of therapy (MDOT). Ten studies (mainly pilots) were identified involving patients with tuberculosis, sickle cell disease and Alzheimer's disease. New studies are ongoing (ClinicalTrials.gov website) in TB, stroke, sickle cell disease, HIV and opioid dependence...
2018: PloS One
https://www.readbyqxmd.com/read/29393720/evaluation-of-clinically-and-physiologically-atypical-asthma-if-it-doesn-t-wheeze-it-may-still-be-asthma
#7
Dorit Ater, Israel Amirav, Matan Attias, Eyal Nakash, Michael T Newhouse, Avigdor Mandelberg
OBJECTIVE: Children with asthma-like symptoms may not clinically wheeze. The objectives of this study were to evaluate if children, without physician-documented wheeze, wheeze during bronchial-challenge-testing (BCT), and if measurements of O2Sat and respiratory rate during BCT improve the BCT sensitivity? METHODS: Seven hundred and twenty-four children, who were referred for suspicion of asthma, performed a BCT. Positive BCT was determined by the provocation concentration (PC) which resulted in a 20% decrease in FEV1 (PC20), (in those who were able to perform spirometry, group B), or (in those unable to perform spirometry, group A) a 50% increase in respiratory rate (PCRR), or a 5% decrease in oxygen-saturation (PCO2-Sat) or appearance of wheezing (PCwheeze)...
February 2, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29380068/impedance-oscillometry-emerging-role-in-the-management-of-chronic-respiratory-disease
#8
REVIEW
Mohammed F Zaidan, Ashwini P Reddy, Alexander Duarte
PURPOSE OF REVIEW: Chronic respiratory diseases affecting adults and children are widely prevalent, so lung function testing is imperative for diagnosis and management. Spirometry is the traditional standard measure of lung function; however, certain groups of patients are unable to provide accurate and reproducible exhalation maneuvers. Consequently, the impedance oscillometry system (IOS) has been developed as an effort, independent technique to assess airway function in children and the elderly...
January 29, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29360392/accuracy-of-optoelectronic-plethysmography-in-childhood-exercise-induced-asthma
#9
Larissa Andrade de Sá Feitosa, Murilo Carlos Amorim de Britto, Andrea Aliverti, Jéssica Brito Noronha, Armèle Dornelas de Andrade
OBJECTIVE: To assess the variations of end-expiratory volume of chest wall (EEVcw) measured by optoelectronic plethysmography (OEP) as a diagnostic tool in exercise-induced asthma (EIA) among asthmatic preschool children. METHODS: Forty children diagnosed with asthma were included in the study. Spirometry was used as a gold standard test for comparison with OEP. A 10% decline in forced expiratory volume in 1 second was considered positive for EIA. OEP was performed with 8 cameras at a frequency of 60 Hz and 89 markers were placed on the thoraco-abdominal surface of participants...
January 23, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29354485/is-forced-oscillation-technique-the-next-respiratory-function-test-of-choice-in-childhood-asthma
#10
REVIEW
Afaf Alblooshi, Alia Alkalbani, Ghaya Albadi, Hassib Narchi, Graham Hall
Respiratory diseases, especially asthma, are common in children. While spirometry contributes to asthma diagnosis and management in older children, it has a limited role in younger children whom are often unable to perform forced expiratory manoeuvre. The development of novel diagnostic methods which require minimal effort, such as forced oscillation technique (FOT) is, therefore, a welcome and promising addition. FOT involves applying external, small amplitude oscillations to the respiratory system during tidal breathing...
December 26, 2017: World Journal of Methodology
https://www.readbyqxmd.com/read/29338960/small-airway-dysfunction-precedes-the-development-of-asthma-in-children-with-allergic-rhinitis
#11
E Skylogianni, M Triga, K Douros, K Bolis, K N Priftis, S Fouzas, M B Anthracopoulos
BACKGROUND: Epidemiological evidence suggests the existence of a direct link between allergic rhinitis (AR) and asthma. Several studies also support the presence of small-airway dysfunction (SAD) in non-asthmatic children with AR. However, it remains unknown whether SAD can predict the progression of AR to asthma. Our objective was to explore the existence of SAD in non-asthmatic children with AR and to assessed its ability to predict the development of asthma. METHODS: Seventy-three 6-year-old children with intermittent moderate-severe AR but without asthma symptoms/medication within the last two years, underwent spirometry and measurement of respiratory resistance (Rrs) and reactance (Xrs) before and after bronchodilation (BD) (300mcg salbutamol)...
January 12, 2018: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/29300537/impulse-oscillometry-and-spirometry-exhibit-different-features-of-lung-function-in-bronchodilation
#12
Youn Ho Sheen, Hye Mi Jee, Eun Kyo Ha, Ho Min Jang, Seung Jin Lee, Shinhae Lee, Kyung Suk Lee, Young-Ho Jung, Sun Hee Choi, Myung Hyun Sohn, Man Yong Han
OBJECTIVE: Bronchodilator responses (BDRs) from impulse oscillometry (IOS) are not interchangeable with those from spirometry. We aimed to identify the characteristics of children with small airway hyperresponsiveness and to determine whether BDR from IOS provides an important supplement to BDR from spirometry. METHODS: The records of 592 children with asthma or suspected asthma who underwent spirometric and oscillometric BDRs were retrospectively reviewed. Oscillometric BDR was defined as positive when relative or absolute changes of Rrs5 or Xrs5 were beyond two standard deviations and spirometric BDR as positive when absolute change of forced expiratory volume in one second (FEV1) was ≥12%...
January 4, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29279789/asthma-screening-in-pediatric-sickle-cell-disease-a-clinic-based-program-using-questionnaires-and-spirometry
#13
Sara C Sadreameli, Rachel O Alade, Peter J Mogayzel, Sharon McGrath-Morrow, John J Strouse
A clinician diagnosis of asthma is associated with increased morbidity and mortality in people with sickle cell disease (SCD). We hypothesized that a screening program would help identify children with asthma needing referral to pulmonary clinic. We conducted a single-center project to screen patients with SCD for asthma using a previously validated questionnaire (Breathmobile) and for pulmonary function abnormalities with portable spirometry. Participants with a positive questionnaire and/or abnormal spirometry were referred to pediatric pulmonary clinic...
December 1, 2017: Pediatric Allergy, Immunology, and Pulmonology
https://www.readbyqxmd.com/read/29279787/acute-chest-syndrome-in-children-with-sickle-cell-disease
#14
REVIEW
Shilpa Jain, Nitya Bakshi, Lakshmanan Krishnamurti
Acute chest syndrome (ACS) is a frequent cause of acute lung disease in children with sickle cell disease (SCD). Patients may present with ACS or may develop this complication during the course of a hospitalization for acute vaso-occlusive crises (VOC). ACS is associated with prolonged hospitalization, increased risk of respiratory failure, and the potential for developing chronic lung disease. ACS in SCD is defined as the presence of fever and/or new respiratory symptoms accompanied by the presence of a new pulmonary infiltrate on chest X-ray...
December 1, 2017: Pediatric Allergy, Immunology, and Pulmonology
https://www.readbyqxmd.com/read/29259760/lung-function-in-severe-pediatric-asthma-a-longitudinal-study-in-children-and-adolescents-in-brazil
#15
Mônica Versiani Nunes Pinheiro de Queiroz, Cristina Gonçalves Alvim, Álvaro A Cruz, Laura Maria de Lima Belizário Facury Lasmar
Background: In severe asthma, high doses of inhaled corticosteroids (ICS) are used in order to achieve clinical and functional control. This study aimed to evaluate lung function in outpatients (children and adolescents) with severe asthma in Brazil, all of whom were treated with high doses of ICS. We evaluated all spirometry tests together and by ICS dose: 800 and > 800 µg/day. Methods: This was a 3-year longitudinal study in which we analyzed 384 spirometry tests in 65 severe asthma patients (6-18 years of age), divided into two groups by the dose of ICS (budesonide or equivalent): 800 and > 800 µg/day...
2017: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/29238123/epidemiology-triggers-and-severity-of-childhood-asthma-in-ilesa-nigeria-implications-for-management-and-control
#16
Bankole Peter Kuti, Kehinde Oluyori Omole
Background: Knowledge about childhood asthma in a locality will assist clinicians to adequately manage the condition. This study set out to report the epidemiology, triggers of exacerbation, comorbid conditions, and severity of childhood asthma at a tertiary health facility in Nigeria and the implication of these, in management and symptoms control. Methods: Over a 15-month study period, children (aged <15 years) with physician-diagnosed asthma were consecutively recruited at the pediatric chest clinic of the hospital...
January 2017: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/29231775/the-airway-hyperresponsiveness-to-methacholine-may-be-predicted-by-impulse-oscillometry-and-plethysmography-in-children-with-well-controlled-asthma
#17
Tugba Arıkoglu, Ayyuce Unlu, Didem Derici Yıldırım, Semanur Kuyucu
OBJECTIVE: Airway hyperresponsiveness (AHR) is a hallmark of asthma. Methacholine challenge test which is mostly used to confirm AHR is not routinely available. The aim of this study was to investigate the predictive values of fractional exhaled nitric oxide (FeNO), impulse oscillometry (IOS), and plethysmography for the assessment of AHR in children with well-controlled asthma. METHODS: 60 children with controlled allergic asthma aged 6-18 years participated in the study...
December 12, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29226507/age-is-the-only-predictor-of-small-decrease-in-lung-function-in-children-with-sickle-cell-anemia
#18
Shaina M Willen, Robyn Cohen, Mark Rodeghier, Fenella Kirkham, Susan S Redline, Carol Rosen, Jane Kirkby, Michael R DeBaun
The longitudinal pattern of lung function in children with sickle cell anemia (SCA) has shown a decrease in FEV1 % predicted, a risk factor for death in adults with SCA, but predictors for this decline are poorly characterized. In a prospective longitudinal multi-center cohort of children with SCA, we tested the hypotheses that: 1) FEV1 % predicted declines over time; and 2) SCA-specific characteristics and therapy predict this decline. At three clinical centers, children with SCA (HbSS or HbSβ0 thalassemia), unselected for respiratory disease, were enrolled in the Sleep and Asthma Cohort (SAC) study...
December 11, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/29178471/methacholine-challenge-test-comparison-of-tidal-breathing-and-dosimeter-methods-in-children
#19
Ahlam Mazi, Larry C Lands, David Zielinski
INTRODUCTION: Methacholine Challenge Test (MCT) is used to confirm, assess the severity and/or rule out asthma. Two MCT methods are described as equivalent by the American Thoracic Society (ATS), the tidal breathing and the dosimeter methods. However, the majority of adult studies suggest that individuals with asthma do not react at the same PC20 between the two methods. Additionally, the nebulizers used are no longer available and studies suggest current nebulizers are not equivalent to these...
November 27, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29160411/spirometry-in-schoolchildren-for-field-studies-does-testing-on-different-days-change-the-result-of-the-exam
#20
Janaina Cristina Scalco, Rafaela Coelho Minsky, Camila Isabel Santos Schivinski
OBJECTIVE: To analyze if there is variation in the results of spirometry performed by healthy schoolchildren on different days. METHODS: Cross-sectional study with healthy schoolchildren aged 7 to 12 years old, in Florianópolis, Santa Catarina, Southern Brazil. Prepubescent children, non-athletes, born at full term, without cardiorespiratory, rheumatic, musculoskeletal, neurological and visual or hearing deficit were included. The child's health was assessed by a health questionnaire and by the survey International Study of Asthma and Allergies in Childhood...
November 13, 2017: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
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