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Asthma, spirometry in children

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https://www.readbyqxmd.com/read/28642859/exercise-induced-bronchospasm-and-allergy
#1
REVIEW
Serena Caggiano, Renato Cutrera, Antonio Di Marco, Attilio Turchetta
Sport is an essential part of childhood, with precious and acknowledged positive health effects but the impact of exercise-induced bronchoconstriction (EIB) significantly reduces participation in physical activity. It is important to recognize EIB, differentiating EIB with or without asthma if the transient narrowing of the airways after exercise is associated with asthmatic symptoms or not, in the way to select the most appropriate treatment among the many treatment options available today. Therapy is prescribed based on symptoms severity but diagnosis of EIB is established by changes in lung function provoked by exercise evaluating by direct and indirect tests...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28612960/physical-activity-and-asthma-control-level-in-children-and-adolescents
#2
Natasha Y Matsunaga, Marina S Oliveira, André M Morcillo, José D Ribeiro, Maria A G O Ribeiro, Adyléia A D C Toro
BACKGROUND AND OBJECTIVE: Physical activity is defined as any bodily movement produced by a muscle contraction with increased energy expenditure. The aim of this study was to assess the physical activity, asthma control level, spirometric measurements and quality of life in children and adolescents with asthma. METHODS: We included all children and adolescents aged 7-17 years who had a diagnosis of atopic asthma and who attended the Pediatric Pulmonology Outpatient Clinic of the State University of Campinas, Brazil...
June 14, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28583260/the-case-for-impulse-oscillometry-in-the-management-of-asthma-in-children-and-adults
#3
REVIEW
Stanley P Galant, Hirsh D Komarow, Hye-Won Shin, Salman Siddiqui, Brian J Lipworth
OBJECTIVE: To provide a clinical rationale for including impulse oscillometry (IOS) as a part of standard office-based asthma assessment. DATA SOURCES: PubMed and Google search, limited to English language and human disease, with the keywords IOS and asthma. STUDY SELECTIONS: Articles included in this review were based on the expert opinion and previous publications by the authors. RESULTS: In children, IOS was more useful than spirometry in identifying asthma and uncontrolled asthma and predicting loss of control and exacerbations...
June 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28554704/duration-and-exclusiveness-of-breastfeeding-and-school-age-lung-function-and-asthma
#4
Evelien R van Meel, Mandy de Jong, Niels J Elbert, Herman T den Dekker, Irwin K Reiss, Johan C de Jongste, Vincent W V Jaddoe, Liesbeth Duijts
BACKGROUND: Breastfeeding reduces the risk of asthma in early childhood, but it is not clear whether its effect on respiratory morbidity is still present in later childhood. OBJECTIVES: To examine the associations of any breastfeeding, breastfeeding duration, and breastfeeding exclusiveness with lung function and asthma in school-aged children and whether associations were influenced by respiratory tract infections and maternal or child's atopic status. METHODS: This study of 4,464 children was embedded in a population-based prospective cohort study...
May 26, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28546471/automated-quality-control-of-forced-oscillation-measurements-respiratory-artifact-detection-with-advanced-feature-extraction
#5
Thuy T Pham, Philip H W Leong, Paul David Robinson, Thomas Gutzler, Adelle S Jee, Gregory G King, Cindy Thamrin
The forced oscillation technique (FOT) can provide unique and clinically relevant lung function information with little cooperation with subjects. However, FOT has higher variability than spirometry, possibly because strategies for quality control and reducing artifacts in FOT measurements have yet to be standardized or validated. Many quality control procedures either rely on simple statistical filters or subjective evaluation by a human operator. In this study, we propose an automated artifact removal approach based on the resistance against flow profile, applied to complete breaths...
May 25, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28527867/association-of-neck-circumference-and-pulmonary-function-in-children
#6
Onur Akın, Mutluay Arslan, Cem Haymana, Erdem Karabulut, Bulent Hacihamdioglu, Suleyman Tolga Yavuz
BACKGROUND: Childhood obesity leads to many complications including impaired respiratory function. There are various anthropometric parameters related to obesity. OBJECTIVE: To investigate the correlation between anthropometric indices and pulmonary function test results in children without asthma. METHODS: Children without any respiratory disorders were enrolled in this study. Anthropometric measurements, such as height, weight, neck circumference (NC), and waist circumference, were obtained from the enrollees and body mass index was calculated...
May 17, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28526251/asthma-related-lung-function-sleep-quality-and-sleep-duration-in-urban-children
#7
Daphne Koinis-Mitchell, Sheryl J Kopel, Ronald Seifer, Monique LeBourgeois, Elizabeth L McQuaid, Cynthia A Esteban, Julie Boergers, Jack Nassau, Michael Farrow, Gregory K Fritz, Robert B Klein
OBJECTIVES: Examine (1) the extent to which changes in objectively measured asthma-related lung function (forced expiratory volume in 1 second) within a sleep period are associated with sleep quality and sleep duration during that sleep period in a group of urban children with persistent asthma, (2) associations between morning and evening asthma-related lung function and sleep quality and duration on the adjacent night, and (3) whether these associations differ by ethnic group. DESIGN: Cross-sectional, multimethod approach...
June 2017: Sleep Health
https://www.readbyqxmd.com/read/28524604/prevalence-of-high-fractional-exhaled-nitric-oxide-among-us-youth-with-asthma
#8
Duong T Nguyen, Brian K Kit, Debra Brody, Lara J Akinbami
BACKGROUND: High fractional exhaled nitric oxide (FeNO) is an indicator of poor asthma control and has been proposed as a non-invasive assessment tool to guide asthma management. OBJECTIVE: We aimed to describe the prevalence of and factors associated with high FeNO among US youth with asthma. METHODS: Data from 716 children and adolescents with asthma ages 6-19 years who participated in the 2007-2012 National Health and Nutrition Examination Survey were analyzed...
June 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28486753/small-airway-function-before-and-after-cold-dry-air-challenge-in-pediatric-asthma-patients-during-remission
#9
Michael Steinbacher, Andreas Pfleger, Gerold Schwantzer, Stefanie Jauk, Elisabeth Weinhandl, Ernst Eber
BACKGROUND: We wanted to compare cold dry air challenge (CACh) induced changes in spirometric parameters with changes in nitrogen multiple breath washout (N2 MBW) parameters in pediatric asthma patients during clinical remission over the past year (ie, with "inactive asthma"). As N2 MBW assesses ventilation heterogeneity we expected to gain detailed information about peripheral airways contribution. METHODS: In subjects with normal spirometry N2 MBW, spirometry and body plethysmography were performed at baseline, after CACh, and after salbutamol inhalation...
May 9, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28442072/predictive-equations-for-maximal-respiratory-pressures-of-children-aged-7-10
#10
George J da Rosa, André M Morcillo, Maíra S de Assumpção, Camila I S Schivinski
BACKGROUND: Measurements of respiratory muscle strength are widely used for assessment in children; however, clearly defined predictive equations for the Brazilian pediatric population have yet to be established. OBJECTIVE: To determine the prediction equations for maximal respiratory pressures in healthy children. METHOD: Cross-sectional observational study with normal-weight students aged 7-10 years (n=399, 198 boys) with health attested by the (International Study of Asthma and Allergies in Childhood) questionnaire and medical history...
January 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28432861/spirometry-and-volumetric-capnography-in-lung-function-assessment-of-obese-and-normal-weight-individuals-without-asthma
#11
Mariana S Ferreira, Roberto T Mendes, Fernando A L Marson, Mariana P Zambon, Maria A R G M Antonio, Ilma A Paschoal, Adyléia A D C Toro, Silvana D Severino, Maria A G O Ribeiro, José D Ribeiro
OBJECTIVE: To analyze and compare lung function of obese and healthy, normal-weight children and adolescents, without asthma, through spirometry and volumetric capnography. METHODS: Cross-sectional study including 77 subjects (38 obese) aged 5-17 years. All subjects underwent spirometry and volumetric capnography. The evaluations were repeated in obese subjects after the use of a bronchodilator. RESULTS: At the spirometry assessment, obese individuals, when compared with the control group, showed lower values of forced expiratory volume in the first second by forced vital capacity (FEV1/FVC) and expiratory flows at 75% and between 25 and 75% of the FVC (p<0...
April 19, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28341820/il-23-gene-and-protein-expression-in-childhood-asthma
#12
Soheila Alyasin, Reza Amin, Ali Fazel, Mohammad Hossein Karimi, Seyed Hesamedin Nabavizadeh, Hossein Esmaeilzadeh, Maryam Babaei
BACKGROUND: Asthma is the chronic inflammation of airways characterized by eosinophilic infiltration, mucus overproduction, airway hyper-responsiveness and airway remodeling. These changes are induced mostly by cytokines which are produced by T helper (Th) 2 cells. Recently, the role of interleukin-23 (IL-23) in the pathogenesis of adult allergic asthma has been studied. OBJECTIVE: To explore IL-23 serum levels and its expression in persistent asthma compared with healthy children younger than five years old...
March 2017: Iranian Journal of Immunology: IJI
https://www.readbyqxmd.com/read/28332939/pediatric-asthma-hospitalizations-among-urban-minority-children-and-the-continuity-of-primary-care
#13
Levon H Utidjian, Alexander G Fiks, A Russell Localio, Lihai Song, Mark J Ramos, Ron Keren, Louis M Bell, Robert W Grundmeier
OBJECTIVE: To examine the effect of ambulatory health care processes on asthma hospitalizations. METHODS: A retrospective cohort study using electronic health records was completed. Patients aged 2-18 years receiving health care from 1 of 5 urban practices between Jan 1, 2004 and Dec 31, 2008 with asthma documented on their problem list were included. Independent variables were modifiable health care processes in the primary care setting: (1) use of asthma controller medications; (2) regular assessment of asthma symptoms; (3) use of spirometry; (4) provision of individualized asthma care plans; (5) timely influenza vaccination; (6) access to primary healthcare; and (7) use of pay for performance physician incentives...
February 25, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28282228/evaluation-of-exhaled-breath-temperature-ebt-as-a-marker-and-predictor-of-asthma-exacerbation-in-children-and-adolescents
#14
Irena Wojsyk-Banaszak, Marcin Mikoś, Aleksandra Szczepankiewicz, Alicja Wielebska, Paulina Sobkowiak, Aleksandra Kamińska, Anna Bręborowicz
INTRODUCTION: Noninvasive and easy-to-use tools to monitor airway inflammation in asthma are needed to maintain disease control, particularly in pediatric population. The aim of the study was to evaluate exhaled breath temperature (EBT) in pediatric respiratory clinic setting. METHODS: We evaluated 37 children and adolescents with asthma (5-17 years; median: 11 years). The patients were followed up in stable condition and during exacerbations (paired observations in n = 19 subjects)...
March 10, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28275111/tidal-breathing-parameters-measured-using-structured-light-plethysmography-in-healthy-children-and-those-with-asthma-before-and-after-bronchodilator
#15
Hamzah Hmeidi, Shayan Motamedi-Fakhr, Edward Chadwick, Francis J Gilchrist, Warren Lenney, Richard Iles, Rachel C Wilson, John Alexander
Structured light plethysmography (SLP) is a light-based, noncontact technique that measures tidal breathing by monitoring displacements of the thoracoabdominal (TA) wall. We used SLP to measure tidal breathing parameters and their within-subject variability (v) in 30 children aged 7-16 years with asthma and abnormal spirometry (forced expiratory volume in 1 sec [FEV1] <80% predicted) during a routine clinic appointment. As part of standard care, the reversibility of airway obstruction was assessed by repeating spirometry after administration of an inhaled bronchodilator...
March 2017: Physiological Reports
https://www.readbyqxmd.com/read/28220034/exhaled-and-nasal-nitric-oxide-in-relation-to-lung-function-blood-cell-counts-and-disease-characteristics-in-cystic-fibrosis
#16
Christina Krantz, Christer Janson, Annika Hollsing, Kjell Alving, Andrei Malinovschi
BACKGROUND: Patients with cystic fibrosis (CF) have similar or lower exhaled nitric oxide (FeNO) and lower nasal nitric oxide (nNO) levels than controls. There are divergent results on alveolar NO (CalvNO) concentrations in relation to CF. There are inconsistent results on correlation between different nitric oxide parameters and lung function and inflammation in CF. AIM: To compare FeNO, CalvNO and nNO levels between subjects with CF, asthma and healthy controls and to study whether these parameters are related to lung function, blood cell counts or clinical characteristics in CF patients...
March 20, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28208225/indoor-fungal-diversity-in-primary-schools-may-differently-influence-allergic-sensitization-and-asthma-in-children
#17
João Cavaleiro Rufo, Joana Madureira, Inês Paciência, Lívia Aguiar, Cristiana Pereira, Diana Silva, Patrícia Padrão, Pedro Moreira, Luís Delgado, Isabella Annesi-Maesano, Eduardo Oliveira Fernandes, João Paulo Teixeira, André Moreira
BACKGROUND: Childhood exposure to microbiologic agents may influence the development of allergic and respiratory diseases. Apart from home, children spend most of their time at school, which represents an environment of significant exposure to indoor air microbes. Therefore, we aimed to assess how the prevalence of allergic sensitization and asthma in schoolchildren is affected by microbiologic exposure within classrooms. METHODS: Spirometry with bronchodilation, exhaled nitric oxide measurements and skin-prick tests data were retrieved from 858 children aged 8-10 years attending 71 classrooms in 20 primary schools...
February 16, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28171771/association-of-perfluoroalkyl-substances-exposure-with-impaired-lung-function-in-children
#18
Xiao-Di Qin, Zhengmin Min Qian, Shyamali C Dharmage, Jennifer Perret, Sarah Dee Geiger, Steven E Rigdon, Steven Howard, Xiao-Wen Zeng, Li-Wen Hu, Bo-Yi Yang, Yang Zhou, Meng Li, Shu-Li Xu, Wen-Wen Bao, Ya-Zhi Zhang, Ping Yuan, Jia Wang, Chuan Zhang, Yan-Peng Tian, Min Nian, Xiang Xiao, Wen Chen, Yungling Leo Lee, Guang-Hui Dong
Previous studies have demonstrated associations between serum levels of perfluoroalkyl substances (PFASs) and asthma or asthma related-biomarkers. However, no studies have reported a possible relationship between PFASs exposure and lung function among children. The objective of the present study is to test the association between PFASs exposure and lung function in children from a high exposure area by using a cross-sectional case-control study, which included 132 asthmatic children and 168 non-asthmatic controls recruited from 2009 to 2010 in the Genetic and Biomarkers study for Childhood Asthma...
May 2017: Environmental Research
https://www.readbyqxmd.com/read/28157474/factors-impacting-asthma-control-in-children-in-a-low-to-middle-income-country-setting-a-retrospective-study
#19
K A Monene, R Masekela
OBJECTIVES: 1) To assess asthma control and its evolution over time among children in a low-to-middle-income country, and 2) to explore whether demographics, type of asthma medication, comorbidities or exacerbations impact asthma control. METHODS: In a retrospective study in children with asthma aged 6-18 years conducted between 2005 and 2010, we collected clinical and demographic data and used Global Initiative for Asthma (GINA) criteria to assess asthma control...
January 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28146643/childhood-lung-function-predicts-adult-copd-and-asthma-copd-overlap-syndrome-acos
#20
Dinh S Bui, John A Burgess, Adrian J Lowe, Jennifer L Perret, Caroline J Lodge, Minh Bui, Stephen Morrison, Bruce R Thompson, Paul S Thomas, Graham G Giles, Judith Garcia-Aymerich, Debbie Jarvis, Michael J Abramson, E Haydn Walters, Melanie C Matheson, Shyamali C Dharmage
RATIONALE: There are limited data on early life risk factors for COPD phenotypes. OBJECTIVE: To investigate the role of childhood lung function in adult spirometrically defined COPD phenotypes. METHOD: Pre-bronchodilator (BD) spirometry was performed for a cohort of 7-year old Tasmanian children. A sub-sample underwent pre-and post-BD spirometry at 45 years. For this analysis, COPD was spirometrically defined as a post-BD FEV1/FVC<lower limit of normal (LLN)...
February 1, 2017: American Journal of Respiratory and Critical Care Medicine
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