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posterior scleritis

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https://www.readbyqxmd.com/read/28394239/management-of-uveitis-and-scleritis-in-necrobiotic-xanthogranuloma
#1
John A Gonzales, Anna Haemel, Andrew J Gross, Nisha R Acharya
Necrobiotic xanthogranuloma (NXG) is a chronic, progressive non-Langerhans histiocytic granulomatous disease. While case reports describing periorbital involvement of NXG are frequent, only a few case reports describing ocular involvement, such as scleritis and uveitis, exist. Herein, we present a case presenting initially as bilateral anterior and posterior scleritis, as well as a chronic bilateral granulomatous panuveitis, and discuss the immunosuppressant options that should be considered for this disease with protean manifestations...
April 10, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28383839/-posterior-scleritis
#2
A C Chapelle, P Blaise, J-M Rakic
Posterior scleritis, a severe and painful inflammation of the sclera, is an often misdiagnosed pathology due to its clinical polymorphism. An accurate diagnosis is however needed in order to propose an appropriate treatment of the ophthalmologic symptoms and to exclude an associated systemic inflammatory or auto-immune pathology.
July 2016: Revue Médicale de Liège
https://www.readbyqxmd.com/read/28355124/ocular-pharmacology-for-scleritis-review-of-treatment-and-a-practical-perspective
#3
Maxwell S Stem, Bozho Todorich, Lisa J Faia
Scleritis is defined as an infectious or noninfectious inflammation of the sclera that can be broadly categorized according to anatomic location (ie, anterior or posterior) and whether the process is necrotizing or non-necrotizing. Treatment for scleritis is dictated by the etiology of the inflammation, with infectious forms requiring treatment of the inciting agent and noninfectious forms requiring treatment of the underlying inflammation with immunosuppression. Pharmacotherapy for noninfectious scleritis can be classified according to delivery route (eg, local or systemic) and mechanism of action (eg, biologic or nonbiologic)...
March 29, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28275605/unrelenting-ocular-pain-as-a-masquerading-symptom-of-occult-choroidal-metastasis
#4
Jordan D Deaner, Renelle Pointdujour-Lim, Emil Anthony T Say, Carol L Shields
PURPOSE: To report a case of chronic eye pain as a presenting feature of choroidal metastasis from lung cancer. METHODS: We report the case of a 58-year-old Caucasian woman with stage IV lung adenocarcinoma presenting with an 8-month history of left eye pain and blurred vision. RESULTS: The patient had previously consulted 14 ophthalmologists with varying diagnoses including posterior scleritis and trigeminal neuralgia. Visual acuity at presentation was 20/20 in the right eye and 20/80 in the left eye...
January 2017: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/28205148/ocular-autoimmune-systemic-inflammatory-infectious-study-oasis-report-4-analysis-and-outcome-of-scleritis-in-an-east-asian-population
#5
Muhammad Amir Bin Ismail, Rachel Hui Fen Lim, Helen Mi Fang, Elizabeth Poh Ying Wong, Ho Su Ling, Wee Kiak Lim, Stephen C Teoh, Rupesh Agrawal
BACKGROUND: The purpose of this study is to evaluate the spectrum of scleritis from database of Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) at a tertiary eye referral eye institute in Singapore. Clinical records of 120 patients with scleritis from a database of 2200 patients from Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) were reviewed. RESULTS: 56.6% were females, with a mean age of 48.6 ± 15.9 years. 75 (62.5%) had diffuse anterior scleritis, 25 (20...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28147399/severe-idiopathic-posterior-scleritis-in-a-patient-with-hiv
#6
M Sherif, L Leon, O Clerc, Y Guex-Crosier
No abstract text is available yet for this article.
February 1, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28140700/adalimumab-for-the-treatment-of-uveitis
#7
Kara C LaMattina, Debra A Goldstein
Adalimumab, an inhibitor of tumor necrosis factor-alpha (TNFα), is the only systemic non-corticosteroid agent which has been approved by the US Food and Drug Administration (FDA) for the treatment of non-infectious uveitis. Areas covered:The aim of this review is to summarize the research which demonstrated the effectiveness of adalimumab in the treatment of intraocular inflammation and helped to establish its side effect profile, ultimately leading to its FDA approval. Expert commentary:Adalimumab is a useful second-line agent in the treatment of non-infectious uveitis...
January 31, 2017: Expert Review of Clinical Immunology
https://www.readbyqxmd.com/read/28007653/poststreptococcal-syndrome-presenting-as-posterior-scleritis-in-a-child
#8
Sarah M Hilkert, Anjum F Koreishi, Dmitry Pyatetsky
Posterior scleritis in children is very rare. In contrast to the adult form, pediatric posterior scleritis has not previously been associated with any systemic disorder. We describe a case of an 11-year-old girl who presented with left eye pain and redness and was found to have posterior scleritis on ultrasonography. Her laboratory work-up revealed a highly elevated antistreptolysin O titer; the rest of her serologic and radiologic evaluation was unremarkable. She was diagnosed with presumed poststreptococcal posterior scleritis and improved with a slow taper of oral steroids...
December 19, 2016: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/27941114/posterior-scleritis-presenting-as-conjunctivitis-in-a-child
#9
Jyotiranjan Mallick, Susant Pujahari, Prafulla Kumar Maharana
A 14-year-old male child presented with redness and decreased vision in the right eye for 7 days. He was being treated for viral conjunctivitis for right eye at a local hospital. His visual acuity was 6/24 OD and 6/9 OS. Slit-lamp examination revealed diffuse conjunctival congestion in the right eye. Dilated fundus examination revealed mild disc hyperaemia and retinal striae in both the eyes. A peripapillary serous detachment of macula in the right eye was seen on optical coherence tomography. B scan ultrasonography revealed increased scleral thickening and characteristic 'T' sign in both the eyes...
December 9, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27918224/ocular-autoimmune-systemic-inflammatory-infectious-study-oasis-report-1-epidemiology-and-classification
#10
Elizabeth J Chen, Muhammad Amir Bin Ismail, Helen Mi, Su Ling Ho, Wee Kiak Lim, Stephen C Teoh, Rupesh Agrawal
PURPOSE: To report the epidemiology and classification of ocular inflammation at a tertiary eye care center in Singapore. METHODS: Retrospective cohort study of the clinical records of consecutive new cases from the Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) database from 2004-2015. RESULTS: A total of 2200 patients were studied from the OASIS database. The most common anatomic diagnosis was anterior uveitis (55.9%), posterior uveitis (17...
December 5, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27849414/clinical-features-and-complications-of-scleritis-in-chinese-patients
#11
Peizeng Yang, Zi Ye, Jihong Tang, Liping Du, Qingyun Zhou, Jian Qi, Liang Liang, Lili Wu, Chaokui Wang, Mei Xu, Yuan Tian, Aize Kijlstra
PURPOSE: To characterize the clinical features of scleritis in Chinese patients. METHODS: The history, demographics, ocular findings, auxiliary examination findings, complications, systemic diseases and therapeutic effects were analyzed retrospectively. RESULTS: The study included 124 male and 169 female patients with scleritis. Anterior and posterior scleritis were, respectively, found in 243 and 42 patients. The other eight patients had both anterior and posterior involvement...
November 16, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27775456/a-case-of-necrobiotic-xanthogranuloma-presenting-as-bilateral-posterior-scleritis
#12
Alenka Lavric, Rupesh Agrawal, Carlos Pavesio
No abstract text is available yet for this article.
October 24, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27762661/clinical-profile-of-patients-with-necrotizing-scleritis-in-a-tertiary-eye-care-center-in-southern-india
#13
Parthopratim Dutta Majumder, Avirupa Ghose, Meenakshi Chidambaram, Sudha K Ganesh, Jyotirmay Biswas
PURPOSE: To report the clinical profile of a series of necrotizing scleritis in an Indian population. METHODS: A retrospective medical record review of 27 consecutive patients with necrotizing scleritis. Patient demographics, ocular and systemic findings, treatment modalities, and visual outcome were recorded. RESULTS: There were 19 males and 8 females (31 eyes) with mean age at presentation of 49.5 years (range: 30-84 years). Underlying immunologically induced disorders was present in 37%...
October 20, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27550224/-diagnosis-and-treatment-of-episcleritis-and-scleritis
#14
C Tappeiner, K Walscheid, A Heiligenhaus
Episcleritis is a benign and self-limiting disease, often with a recurrent course, manifesting mainly in young adults. In less than a third of patients, an associated systemic disease can be found. In contrast, scleritis is observed mainly in patients between the 4th and 6th decade of life, may lead to severe ocular complications, and is often associated with a systemic rheumatological disease. Diffuse, nodular, and necrotizing forms of scleritis can be differentiated. Necrotizing and posterior scleritis have a higher risk of complications and worse visual outcome...
September 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27495133/trigeminal-autonomic-cephalgia-caused-by-recurrent-posterior-scleritis
#15
Ali Alim-Marvasti, Jason Ho, Mark Weatherall, Maneesh Patel, Sheena George, Stuart Viegas
A 40-year-old woman presented with a side-locked headache with autonomic features, which then switched sides before reverting to the original side. The atypical features of side swapping, partial response to indometacin and abnormal optic disc appearances ultimately led to a diagnosis of recurrent posterior scleritis. We discuss the differential diagnosis of trigeminal autonomic cephalgias and its secondary causes, and provide practical pointers for its investigation and management.
August 5, 2016: Practical Neurology
https://www.readbyqxmd.com/read/27472515/tarantula-hair-associated-panuveitis-treated-with-sustained-release-intravitreal-dexamethasone-implant
#16
Melina I Morkin, Lana M Rifkin, Sabin Dang, Caroline R Baumal
PURPOSE: To report a case of tarantula hair-induced panuveitis treated with sustained-release intravitreal dexamethasone implant and followed by sequential spectral domain optical coherence tomography imaging. METHODS: Findings on clinical examination, anterior segment optical coherence tomography, corneal in vivo confocal microscopy, color fundus photos, fluorescein angiography, and retinal spectral domain optical coherence tomography are presented. Sequential optical coherence tomography images demonstrated the course of the chorioretinal lesions before and after sustained-release intravitreal dexamethasone implant...
July 28, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27444937/ct-and-mr-imaging-in-the-diagnosis-of-scleritis
#17
M C Diogo, M J Jager, T A Ferreira
Scleritis is a rare, underdiagnosed vision-threatening condition that can occur isolated or in association with other orbital abnormalities. The etiology of scleritis is mainly inflammatory noninfectious, either idiopathic or in the context of systemic disease. Ultrasonography remains the criterion standard in diagnostic imaging of this condition but might prove insufficient, and studies on the diagnostic value of CT and MR imaging are lacking. We retrospectively analyzed 11 cases of scleritis in which CT and/or MR imaging were performed during the active phase of disease and assessed the diagnostic utility of these techniques...
December 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27428361/clinical-spectrum-of-hla-b27-associated-ocular-inflammation
#18
Kessara Pathanapitoon, Emilio M Dodds, Emmett T Cunningham, Aniki Rothova
Human leukocyte antigen (HLA)-B27-associated anterior uveitis (AU) is the most commonly diagnosed form of AU and represents the largest entity of non-infectious uveitis around the world. The most typical ocular manifestation associated with HLA-B27 consists of unilateral AU of acute onset. The HLA-B27-associated acute AU represents a distinct clinical entity occurring typically in young adults between the ages of 20 and 40 years. HLA-B27-associated acute AU is typically unilateral and lasts usually several weeks and diminishes within 3 months in the majority of patients...
July 18, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27224075/isolated-posterior-scleritis-associated-with-tuberculosis
#19
Ana Filipa Miranda, João Cardoso, Nadine Marques, Sandra Barros, Paula Telles, Nuno Campos
Ocular tuberculosis (TB) is considered to be rare, although its incidence has varied widely over time and in different populations. Latent TB is diagnosed when a person is infected with Mycobacterium tuberculosis but does not have active TB. During the last decade, interferon-gamma release assay tests have been developed that allow identification of patients with latent TB infection with better specificity than the tuberculin skin test and can differentiate between infection and prior vaccination. Although rare, tuberculous scleritis should be considered in the differential diagnosis of posterior scleritis...
April 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/27193122/an-unusual-case-of-ocular-tuberculosis-presenting-as-subretinal-abscess-with-posterior-scleritis
#20
Rajeev Reddy Pappuru, Vivek Pravin Dave
We report an unusual presentation of ocular tuberculosis with subretinal abscess with associated posterior scleritis. This is a first-of-its-kind report of such an association. A 26-year-old female presented to us with complaints of redness, pain, and decreased vision in her left eye since 1 week. On examination, the vision in her right eye was 6/6 and in the left eye was 1/60. Detailed ocular evaluation revealed exudative retinal detachment, subretinal abscess, and disk edema. Ocular and systemic investigations were consistent with presumed tubercular etiology and posterior scleritis...
February 2017: International Ophthalmology
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