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androgenetic alopecia

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https://www.readbyqxmd.com/read/28932074/mesotherapy-with-dutasteride-in-the-treatment-of-androgenetic-alopecia
#1
David Saceda-Corralo, Ana Rita Rodrigues-Barata, Sergio Vañó-Galván, Pedro Jaén-Olasolo
No abstract text is available yet for this article.
July 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/28932068/familial-cicatricial-alopecia-report-of-familial-frontal-fibrosing-alopecia-and-fibrosing-alopecia-in-a-pattern-distribution
#2
Dandara Meurer Missio, Maria Fernanda Reis Gavazzoni Dias, Ralph Michel Trüeb
Frontal fibrosing alopecia (FFA) and fibrosing alopecia in a pattern distribution (FAPD) as originally reported by Kossard in 1994 and by Zinkernagel and Trüeb in 2000, respectively, represent two distinct patterns of cicatricial pattern hair loss. Both share a patterned distribution and histological evidence of a lichenoid follicular inflammation with fibrosis. FFA is characterized by a marginal alopecia along the frontotemporal hairline, and FAPD by a progressive alopecia of the centroparietal scalp. Since the original reports, evidence has accumulated that there exists considerable clinical overlap among FFA, FAPD, and lichen planopilaris, with coexistence of features of the three conditions within the same individual...
July 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/28932067/extensive-donor-site-keloids-in-follicular-unit-extraction-hair-transplantation
#3
Shimona Garg, Anand Kumar, Ankita Tuknayat, Gurvinder Pal Thami
Hair transplantation, a generally regarded as a safe surgical modality for the treatment of androgenetic alopecia, is not without its potential risks and complications. A case of an extensive keloid formation at donor site following follicular unit extraction is discussed. Hair transplant surgeons should be aware of this significant potential complication, especially in patients having previous keloidal tendencies to avoid such disastrous outcomes.
July 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/28925637/hair-loss-common-causes-and-treatment
#4
T Grant Phillips, W Paul Slomiany, Robert Allison
Hair loss is often distressing and can have a significant effect on the patient's quality of life. Patients may present to their family physician first with diffuse or patchy hair loss. Scarring alopecia is best evaluated by a dermatologist. Nonscarring alopecias can be readily diagnosed and treated in the family physician's office. Androgenetic alopecia can be diagnosed clinically and treated with minoxidil. Alopecia areata is diagnosed by typical patches of hair loss and is self-limited. Tinea capitis causes patches of alopecia that may be erythematous and scaly and must be treated systemically...
September 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/28912032/androgens-and-androgen-receptor-action-in-skin-and-hair-follicles
#5
REVIEW
Julieta María Ceruti, Gustavo José Leirós, María Eugenia Balañá
Beyond sexual functions, androgens exert their action in skin physiology and pathophysiology. Skin cells are able to synthesize most of active androgens from gonadal or adrenal precursors and the enzymes involved in skin steroidogenesis are implicated both in normal or pathological processes. Even when the role of androgens and androgen receptor (AR) in skin pathologies has been studied for decades, their molecular mechanisms in skin disorders remain largely unknown. Here, we go over recent studies of androgens and AR roles in several skin-related disorders, focusing in the current understanding of its molecular mechanisms in androgenetic alopecia (AGA)...
September 11, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28905175/the-promotion-of-hair-regrowth-by-topical-application-of-a-perilla-frutescens-extract-through-increased-cell-viability-and-antagonism-of-testosterone-and-dihydrotestosterone
#6
Jing-Jie Li, Zheng Li, Li-Juan Gu, Kang-Ju Choi, Dong-Seon Kim, Ho-Kyoung Kim, Chang-Keun Sung
This study investigated the potential hair regrowth effects associated with a plant extract of Perilla frutescens, which was selected due to its putative hair regrowth activity. Extracts were prepared from dried P. frutescens suspended in distilled water, where the resultant aqueous suspension was fractionated sequentially using hexane, ethyl acetate, n-butanol, and distilled water. We observed that the n-butanol fraction resulted in the highest hair regrowth activity. The n-butanol soluble fraction of P. frutescens extract (BFPE) was further separated using AB-8 macroporous resin and silica gel chromatography to obtain rosmarinic acid (RA), which demonstrated effective hair growth regeneration potential...
September 13, 2017: Journal of Natural Medicines
https://www.readbyqxmd.com/read/28856798/digit-ratio-2d-4d-is-a-possible-indicator-for-androgenetic-alopecia-in-males
#7
Mehmet Unal
BACKGROUND: Androgenetic alopecia (AGA) is the most common hair loss. The 2D:4D digit ratio refers to the ratio of the length of the second finger to that of the fourth finger and is thought as a marker of prenatal androgen exposure. OBJECTIVES: There are many studies which have examined the relationship between 2D:4D ratio and some other diseases. In this study, we evaluated the relationship between digit ratio 2D:4D and AGA. METHODS: The study group was composed of a male with AGA and healthy controls...
August 29, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28839391/adult-onset-hair-casts-nits-which-do-not-itch
#8
Archana Jagdish Lokhande, Amita Sutaria
Hair casts (HCs) are thin, elongated, firm, whitish cylindrical concretions which ensheath the hair shaft and can be easily dislodge. They are of two different types: peripilar and parakeratotic keratin cast. Due to its clinical resemblance to pediculosis capitis, the entity is also known as pseudonits. Al though not unusual, false diagnoses are common, and thus, it is very important to correctly differentiate it from other similar conditions. We report here a case of HC involving scalp as well as body hair in association with androgenetic alopecia in a 22-year-old male patient...
April 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/28798373/glycolipid-and-hormonal-profiles-in-young-men-with-early-onset-androgenetic-alopecia-a-meta-analysis
#9
Rossella Cannarella, Sandro La Vignera, Rosita A Condorelli, Aldo E Calogero
Hormonal and metabolic abnormalities have been reported in men with early-onset androgenetic alopecia (AGA). Although this has been ascribed to the existence of a male polycystic ovary syndrome (PCOS)-equivalent, data on this topic are inconsistent and this syndrome has not been already acknowledged. To evaluate if, already before the age of 35 years, any difference occurs in the glycolipid and hormonal profiles and in the body weight in men with AGA compared to age-matched controls, we performed a comprehensive meta-analysis of all the available observational case-control studies of literature, using MEDLINE, Google Schoolar and Scopus databases...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28791288/a-practical-approach-to-the-diagnosis-and-management-of-hair-loss-in-children-and-adolescents
#10
REVIEW
Liwen Xu, Kevin X Liu, Maryanne M Senna
Hair loss or alopecia is a common and distressing clinical complaint in the primary care setting and can arise from heterogeneous etiologies. In the pediatric population, hair loss often presents with patterns that are different from that of their adult counterparts. Given the psychosocial complications that may arise from pediatric alopecia, prompt diagnosis and management is particularly important. Common causes of alopecia in children and adolescents include alopecia areata, tinea capitis, androgenetic alopecia, traction alopecia, trichotillomania, hair cycle disturbances, and congenital alopecia conditions...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28771982/original-article-platelet-rich-plasma-with-microneedling-in-androgenetic-alopecia-along-with-dermoscopic-pre-and-post-treatment-evaluation
#11
Abhijeet Kumar Jha, Uday Kumar Udayan, Prasoon Kumar Roy, Amar Kant Jha Amar, R K P Chaudhary
BACKGROUND: Platelet-rich plasma has shown beneficial effects in the treatment of androgenic alopecia with its growth factor properties in accelerating the dermal papilla. Dermoscopy is a noninvasive method that allows the in vivo evaluation of microstructures not visible to the naked eye. OBJECTIVE: To ascertain the role of platelet-rich plasma (PRP) with microneedling, and to compare the pre- and post-treatment dermoscopic features in androgenetic alopecia. (AGA)...
August 3, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28761311/the-association-between-exercise-and-androgenetic-alopecia-a-survey-based-study
#12
Jaewoong Choi, Myungsoo Jun, Solam Lee, Sung-Soo Oh, Won-Soo Lee
No abstract text is available yet for this article.
August 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28761259/a-comparative-study-of-microneedling-with-platelet-rich-plasma-plus-topical-minoxidil-5-and-topical-minoxidil-5-alone-in-androgenetic-alopecia
#13
Kaksha B Shah, Aarti N Shah, Rekha B Solanki, Ranjan C Raval
CONTEXT: There are very few studies evaluating efficacy of platelet-rich plasma (PRP) in hair restoration and its combination with microneedling. As far as ascertained, there is no study to evaluate efficacy of microneedling with PRP plus topical minoxidil (5%) versus topical minoxidil (5%) alone in androgenetic alopecia (AGA). AIMS: This study aims (1) to compare the efficacy of (a) topical minoxidil (5%) alone and (b) topical minoxidil (5%) + microneedling with PRP in men between 18 and 50 years with AGA Grade III to V vertex (Norwood-Hamilton scale) and (2) to perform objective and subjective evaluation based on clinical improvement and photographic evidence...
January 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/28743526/change-in-psa-concentration-in-men-with-psa-2-5-ng-ml-taking-low-dose-finasteride-or-dutasteride-for-male-androgenetic-alopecia
#14
Ho Won Kang, Myeong Heon Chae, Su Hyun Park, Sung Pil Seo, Won Tae Kim, Yong-June Kim, Seok-Joong Yun, Sang-Cheol Lee, Tae Young Yoon, Wun-Jae Kim
PURPOSE: This retrospective cohort study aimed to assess the effect on PSA concentrations of low-dose finasteride or dutasteride treatment for male androgenetic alopecia whose baseline serum PSA < 2.5 ng/mL. PATIENTS AND METHODS: The cohort consisted of 1,379 consecutive male patients who were treated for androgenetic alopecia with finateride 1.25 mg daily or dutasteride 0.5 mg every 3 days in 2002-2012 and underwent PSA measurements at baseline and at least once thereafter...
July 22, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28725654/stem-cells-from-human-hair-follicles-first-mechanical-isolation-for-immediate-autologous-clinical-use-in-androgenetic-alopecia-and-hair-loss
#15
Pietro Gentile, Maria G Scioli, Alessandra Bielli, Augusto Orlandi, Valerio Cervelli
BACKGROUND: Hair follicles are known to contain a well-characterized niche for adult stem cells: the bulge, which contains epithelial and melanocytic stem cells. Stem cells in the hair bulge, a clearly demarcated structure within the lower permanent portion of hair follicles, can generate the interfollicular epidermis, hair follicle structures, and sebaceous glands. The bulge epithelial stem cells can also reconstitute in an artificial in vivo system to a new hair follicle. METHODS: In this study, we have developed a new method to isolate human adult stem cells by mechanical centrifugation of punch biopsy from human hair follicles without culture condition...
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28722459/-mesotherapy-in-trichology
#16
Stephanie Alexandra Ihrisky
Mesotherapy (from Greek meso = in between, therapeia = treat) is a non-surgical, mostly cosmetic therapy, where active substances are injected intradermally into a depth of about 4 mm. It is an effective and easy-to-use method in the treatment of alopecia. It is effective both in the therapy of androgenetic alopecia and telogen effluvium. In recent years, it has been massively expanded also among non-medical fields, which has caused its contradictory perception by professional medical circles outside dermatologists...
2017: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/28722458/-androgenetic-alopecia-in-women
#17
Jana Krabcová
Androgenetic alopecia is one of the most common diagnoses in a hair clinic. It is non-scarring pattern hair losses that affect individuals, independent on severity, age and gender. The incidence of AGA increases within the age. AGA affects women less frequently, is usually milder and is associated with diffuse thinning of the hair scalp. Prompt diagnosis and treatment are essential for obtaining optimal outcome.
2017: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/28711970/does-a-male-polycystic-ovarian-syndrome-equivalent-exist
#18
REVIEW
R Cannarella, R A Condorelli, L M Mongioì, S La Vignera, A E Calogero
The occurrence of a genetic background in the etiology of polycystic ovarian syndrome (PCOS) represents the rational basis to postulate the existence of a male PCOS equivalent. Hormonal and metabolic abnormalities have been described in male relatives of women with PCOS. These males also have a higher prevalence of early onset (<35 years) androgenetic alopecia (AGA). Hence, this feature has been proposed as a clinical sign of the male PCOS equivalent. Clinical evidence has shown that men with early onset AGA have hormonal and metabolic abnormalities...
July 15, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28702978/the-evolution-of-artificial-hair-implantation
#19
M Agrawal, J Lotti, K França, M Fioranelli, M G Roccia, T Lotti
From the beginning, artificial hair implantation has aroused a lot of interest, sometimes controversial, in the field of hair restoration. The artificial fiber must be of high quality and biocompatible. Biofibre® is a very fine fiber having diameter of 80 m. The standard length of this fiber is 15 or 30 cm, to satisfy multiple patient requests. They are available in 13 colors and 3 different shapes (straight, wavy and curly). Artificial hair implant is indicated in all (male and female) cases of androgenetic alopecia, especially for those who show dismal response to medical therapies and have poor donor area supply for hair transplantation...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28691187/therapeutic-experience-with-oral-finasteride-for-androgenetic-alopecia-in-female-to-male-transgender-patients
#20
O M Moreno-Arrones, A Becerra, S Vano-Galvan
BACKGROUND: Androgenic treatment of female-to-male transgender patients may result in androgenetic alopecia (AGA). Use of 5-alpha-reductase inhibitors are useful as oral treatment of AA in men. There are no previous studies of the use of finasteride in transgender men as treatment of AGA. AIM: To evaluate the effectiveness and safety of an oral 5α-reductase inhibitor (finasteride) for AA developed in transgender men. METHODS: This single-centre retrospective study enrolled female-to-male transgender patients with a clinical diagnosis of AGA to receive 1 mg of an oral type II 5α-reductase inhibitor for at least 12 months...
July 10, 2017: Clinical and Experimental Dermatology
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