keyword
MENU ▼
Read by QxMD icon Read
search

androgenetic alopecia

keyword
https://www.readbyqxmd.com/read/29331373/establishment-and-characterization-of-five-immortalized-human-scalp-dermal-papilla-cell-lines
#1
Mi Hee Kwack, Jung Min Yang, Gong Hee Won, Moon Kyu Kim, Jung Chul Kim, Young Kwan Sung
Dermal papilla (DP) regulates the growth and cycling of hair follicles. Cultured DP cells are useful for the study of their role in relation to hair growth and regeneration. However, cultivation of human DP cells is tedious and difficult. In addition, cultured DP cells possess a relatively short replicative life span, requiring immortalized human DP cell lines. We previously established an immortalized human DP cell line, SV40T-hTERT-DPC, by introducing human telomerase reverse transcriptase (hTERT) gene into the transformed cell line, SV40T-DPC...
January 10, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29330930/gender-specific-risk-factors-for-androgenetic-alopecia-in-the-korean-general-population-associations-with-medical-comorbidities-and-general-health-behaviors
#2
Bo-Kyung Kim, Sung Jay Choe, Hee-Chul Chung, Sung-Soo Oh, Won-Soo Lee
BACKGROUND: The relationships between androgenetic alopecia (AGA) and various factors related to metabolic syndrome have been demonstrated in previous studies. However, it remains unclear because of inconsistent results. We investigated the associations between AGA and various risk factors related to metabolic syndrome according to gender. METHODS: We conducted a population-based cross-sectional survey of 2028 Koreans (1050 men, 978 women). The basic and specific (BASP) classification was used for diagnosis of AGA...
February 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29319278/the-use-of-minoxidil-in-the-treatment-of-male-and-female-androgenetic-alopecia-a-story-of-more-than-30-years
#3
Mauro Barbareschi
Even if minoxidil has been known for over 30 years as "hair growth stimulator" the precise mechanism of its action is not completely elucitated. Minoxidil shortens telogen, accelerates telogen-exogen phase and causes the premature entry of resting hair follicles into anagen phase. Moreover, minoxidil increases hair follicle size. A large part of hair treatment scientific literature confirms the efficacy of topically applied minoxidil in humans. In particular, patients treated with minoxidil showed a significant increase in "non vellus" hair count starting from baseline...
February 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29241753/alopecia-and-the-metabolic-syndrome
#4
Cheryl Lie, Choon Fong Liew, Hazel H Oon
Hair loss is a common condition that affects most people at some point in their lives. It can exist as an isolated problem or with other diseases and conditions. Androgenetic alopecia (AGA) and its association with the metabolic syndrome (MetS) have received increasing interest since 1972, when the first link between cardiovascular risk factors and hair loss was raised. We have reviewed studies concerning the relationship between alopecia and MetS. Many studies have investigated the relationship among AGA and MetS and its individual components, particularly in men, where a disproportionately large number of these studies supports this association...
January 2018: Clinics in Dermatology
https://www.readbyqxmd.com/read/29237093/serum-androgens-and-psa-levels-in-androgenetic-alopecia-is-there-a-difference-between-frontal-and-vertex-baldness
#5
Anna Lis-Święty, Hubert Arasiewicz, Irmina Ranosz-Janicka, Ligia Brzezińska-Wcisło
BACKGROUND: Androgenetic alopecia (AGA) seems to be a marker of increased risk of prostate cancer (PCa). OBJECTIVE: We sought to investigate potential pathophysiological differences between frontal and vertex balding that might have the impact on the incidence of PCa. METHODS: Serum concentrations of testosterone (T), dihydrotestosterone (DHT) and prostate-specific antigen (PSA) were measured in 88 subjects with AGA. RESULTS: We have examined sixty patients with frontal baldness and 28 patients with vertex baldness...
December 13, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29224248/is-there-a-pathogenetic-link-between-frontal-fibrosing-alopecia-androgenetic-alopecia-and-fibrosing-alopecia-in-a-pattern-distribution
#6
A Katoulis, K Diamanti, D Sgouros, A I Liakou, E Bozi, G Avgerinou, I Panayiotides, D Rigopoulos
Frequent coexistence of frontal fibrosing alopecia (FFA) and androgenetic alopecia (AGA) has been reported in the literature, but little attention has been given to the pathogenetic mechanisms underlying this potential association. FFA is characterized by progressive cicatricial fronto-temporal hairline recession, mostly affecting peri-menopausal women. Immune mechanisms seem to play a pivotal pathogenetic role. This article is protected by copyright. All rights reserved.
December 10, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29224108/negative-impact-of-testosterone-deficiency-and-5%C3%AE-reductase-inhibitors-therapy-on-metabolic-and-sexual-function-in-men
#7
Abdulmaged M Traish
Androgens are steroid hormones with pleotropic and diverse biochemical and physiological functions, and androgen deficiency exerts a negative impact on human health. Testosterone (T) either directly or via its transformation into the more potent metabolite 5α-dihydrotestosterone (5α-DHT) or via aromatization into estradiol (E2) modulates important biochemical signaling pathways of human physiology and plays a critical role in the growth and/or maintenance of functions in a host of tissues and organs. T and 5α-DHT play an important role in regulating physiology of the muscle, adipose tissue, liver, bone, and central nervous system, as well as reproductive and sexual functions...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29204390/platelet-rich-plasma-by-single-spin-process-in-male-pattern-androgenetic-alopecia-is-it-an-effective-treatment
#8
Arshdeep
No abstract text is available yet for this article.
November 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29204389/platelet-rich-plasma-by-single-spin-process-in-male-pattern-androgenetic-alopecia-is-it-an-effective-treatment
#9
Azin Ayatollahi, Hamed Hosseini, Majid Shahdi, Saman AhmadNasrollahi, Mansour NassiriKashani, Somaye Yadangi, Farid H Firooz, Alireza Firooz
Introduction and Objective: Platelet-rich plasma (PRP) is an autologous preparation of platelets in concentrated plasma. The platelet is a natural source of different growth factors and cytokines. These growth factors act on stem cells in the bulge area of the follicles and stimulate the development of new follicles, and promote neovascularization. The aim of this study was to investigate the efficacy and safety of PRP injections in androgenetic alopecia (AGA) in men. Patients and Methods: Fifteen male patients (mean age: 39 ± 9...
November 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29194786/microneedling-for-the-treatment-of-hair-loss
#10
REVIEW
Raymond M Fertig, A Caresse Gamret, Jessica Cervantes, Antonella Tosti
Microneedling is a minimally invasive dermatological procedure in which fine needles are rolled over the skin to puncture the stratum corneum. This therapy is used to induce collagen formation, neovascularization, and growth factor production of treated areas. It has been used in a wide range of dermatologic conditions, including androgenetic alopecia and alopecia areata, among others. While there are a limited number of studies examining this therapy in the use of hair loss, microneedling has been successfully paired with other hair growth promoting therapies, such as minoxidil, platelet rich plasma, and topical steroids, and shown to stimulate hair follicle growth...
December 1, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29192995/regulatory-pathways-implicated-in-male-androgenetic-alopecia-pathogenesis
#11
E G Y Chew
No abstract text is available yet for this article.
November 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/29184811/dermatologic-manifestations-of-endocrine-disorders
#12
REVIEW
Michael Lause, Alisha Kamboj, Esteban Fernandez Faith
The skin serves as a window for clinicians to understand, diagnose, and monitor endocrine disease. Dermatologic manifestations of endocrinopathies contribute significantly to an individual's health and quality of life. In this review, we outline various disorders of the hypothalamic-pituitary axis, thyroid gland, pancreas, adrenal gland, and androgen axis as well as hereditary endocrine syndromes. In acromegaly, glycosaminoglycan deposition contributes to a thickening of skin and soft tissue, which manifests as coarsening and enlargement of facial and acral structures...
October 2017: Translational pediatrics
https://www.readbyqxmd.com/read/29181579/mediterranean-diet-fresh-herbs-and-fresh-vegetables-decrease-the-risk-of-androgenetic-alopecia-in-males
#13
Cristina Fortes, S Mastroeni, T Mannooranparampil, D Abeni, A Panebianco
It is well established that Androgenetic Alopecia (AGA) occurs in genetically predisposed individuals but little is known of its non-genetic risk factors. The aim of the study was to investigate the role of the Mediterranean diet in determining the risk of AGA. A hospital-based case-control study was conducted in the outpatient clinics of the hospital "Istituto Dermopatico dell'Immacolata, Rome, Italy". We included 104 males and 108 controls not affected by AGA. Controls were frequency matched to cases. Information on socio-demographic characteristics, medical history, smoking and diet were collected for all patients...
November 27, 2017: Archives of Dermatological Research
https://www.readbyqxmd.com/read/29177147/exogen-hairs-in-women-with-and-without-hair-loss
#14
Marcella Guarrera, Alfredo Rebora
Contrary to the classical view of the hair cycle, in which telogen is the resting phase that precedes the release of the hair shaft, another phase has been introduced, exogen. Exogen is the phase wherein the processes for the release of the hair shaft are initiated and successfully executed. Exogen ends when the shaft is liberated. Accordingly, human hairs would be preferably released not with telogen but with exogen roots. To better understand this somehow revolutionary point and what occurs in telogen effluvium (TE) and in androgenetic alopecia (AGA), we undertook a morphological study...
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29167734/treatment-of-chronic-telogen-effluvium-with-oral-minoxidil-a-retrospective-study
#15
Eshini Perera, Rodney Sinclair
Background: Chronic telogen effluvium (CTE) may be primary or secondary to various causes, including drug reaction, nutritional deficiency and female pattern hair loss (FPHL).  Oral minoxidil stimulates hair growth, and topical minoxidil is used in the treatment of FPHL and male androgenetic alopecia. minoxidil has not been used to treat CTE. This study aimed to assess the treatment of CTE with once daily oral minoxidil. Methods: Women with a diagnosis of CTE based on >6 month history of increased telogen hair shedding, no visible mid frontal scalp hair loss (Sinclair stage 1) and no hair follicle miniaturization on scalp biopsy were treated with once daily oral minoxidil...
2017: F1000Research
https://www.readbyqxmd.com/read/29166518/yellow-dots-in-trichoscopy-relevance-clinical-significance-and-peculiarities
#16
Caren Dos Santos Lima, Luciana Rodino Lemes, Daniel Fernandes Melo
Yellow dots are follicular ostium filled with keratin and/or sebum. Initially, they were exclusively associated with alopecia areata. Currently they have also been described in androgenetic alopecia, chronic cutaneous (discoid) lupus erythematosus, and dissecting cellulitis. Due to the growing importance of trichoscopy and its findings in the evaluation of the scalp, this article describes the main diseases in which yellow dots are a common trichoscopic finding, highlighting its characteristics in each dermatosis...
September 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29166130/the-clinical-effect-of-jetppeel-assisted-topical-minoxidil-in-the-treatment-of-androgenetic-alopecia-a-randomized-pilot-study
#17
Lin Gong, Linlin Bao, Tian Tian, Yuanhong Li
OBJECTIVE: We used JetPeel, combined with topical minoxidil to treat patients with AGA, in order to observe whether the JetPeel can accelerate the recovery of the disease and find a new method for AGA treatment. METHOD: Thirty patients who met the standard were included in the study. The patients were randomly divided into three groups. The first group was treated with JetPeel-assisted topical minoxidil. The second group received topical minoxidil monotherapy. The third group was not given any treatment...
November 22, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29146897/gwas-for-male-pattern-baldness-identifies-71-susceptibility-loci-explaining-38-of-the-risk
#18
Nicola Pirastu, Peter K Joshi, Paul S de Vries, Marilyn C Cornelis, Paul M McKeigue, NaNa Keum, Nora Franceschini, Marco Colombo, Edward L Giovannucci, Athina Spiliopoulou, Lude Franke, Kari E North, Peter Kraft, Alanna C Morrison, Tõnu Esko, James F Wilson
Male pattern baldness (MPB) or androgenetic alopecia is one of the most common conditions affecting men, reaching a prevalence of ~50% by the age of 50; however, the known genes explain little of the heritability. Here, we present the results of a genome-wide association study including more than 70,000 men, identifying 71 independently replicated loci, of which 30 are novel. These loci explain 38% of the risk, suggesting that MPB is less genetically complex than other complex traits. We show that many of these loci contain genes that are relevant to the pathology and highlight pathways and functions underlying baldness...
November 17, 2017: Nature Communications
https://www.readbyqxmd.com/read/29141068/new-insight-into-the-pathophysiology-of-hair-loss-trigger-a-paradigm-shift-in-the-treatment-approach
#19
Neil S Sadick, Valerie D Callender, Leon H Kircik, Sophia Kogan
<p>Hair loss affects millions of men and women of all ages and ethnicities, impacting appearance, social interactions, and psycho-emotional well-being. Although a number of options are available, they are limited, carry a potential risk of side effects, and none have proven to be comprehensive for treatment of hair loss. Across the spectrum of hair loss disorders, there has long been a segmentation into distinct mechanisms, driving the main trend in current therapeutics to focus on targeting single molecules or pathways...
November 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29139043/early-onset-baldness-and-the-risk-of-aggressive-prostate-cancer-findings-from-a-case-control-study
#20
Nathan P Papa, Robert J MacInnis, Dallas R English, Damien Bolton, Ian D Davis, Nathan Lawrentschuk, Jeremy L Millar, Gianluca Severi, John L Hopper, Graham G Giles
PURPOSE: We aimed to evaluate the associations between androgenetic alopecia at a young age and subsequent development of aggressive prostate cancer (PC). METHODS: Using a case-control design with self-administered questionnaire, we evaluated the association between aggressive PC and very early-onset balding at age 20, and early-onset balding at age 40 years in 1,941 men. Cases were men with high-grade and/or advanced stage cancer and controls were clinic based men who had undergone biopsy and were found to be histologically cancer negative...
November 14, 2017: Cancer Causes & Control: CCC
keyword
keyword
28037
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"