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Malihe Sabeti, Reza Boostani, Karim Rastgar
Accurate differentiation of mental fatigue levels by analyzing electroencephalogram (EEG) features is still a challenge. This deficiency is rooted in the inability of conventional EEG features to reveal significant changes amongst fatigue levels. From a different perspective, it is evident for evaluating the amount of alertness that characterizing the P300 component is widely used by performing a recognition task. The goal of this study is to classify the pre-task and post-task fatigue levels by tracking the spatial activation of their P300 sources compared to differentiating the P300 waveform features...
2018: Journal of Integrative Neuroscience
Eshwar G Ghumare, Maarten Schrooten, Rik Vandenberghe, Patrick Dupont
Time-varying connectivity analysis based on sources reconstructed using inverse modeling of electroencephalographic (EEG) data is important to understand the dynamic behaviour of the brain. We simulated cortical data from a visual spatial attention network with a time-varying connectivity structure, and then simulated the propagation to the scalp to obtain EEG data. Distributed EEG source modeling using sLORETA was applied. We compared different dipole (representing a source) selection strategies based on their time series in a region of interest...
January 27, 2018: Brain Topography
John Emmanuel Kiat, Michael D Dodd, Robert F Belli, Jacob E Cheadle
Neuroimaging based investigations of change blindness, a phenomenon in which seemingly obvious changes in visual scenes fail to be detected, have significantly advanced our understanding of visual awareness. The vast majority of prior investigations, however, utilize paradigms involving visual disruptions (e.g. intervening blank screens, saccadic movements, "mudsplashes"), making it difficult to cleanly isolate neural responses towards undetected visual changes. To address this issue in this present study, high-density EEG data (256 channel) was collected from 25 participants using a paradigm in which visual changes were progressively introduced into detailed real-world scenes without the use of visual disruption...
January 24, 2018: Journal of Neurophysiology
Navkiran Kalsi, Renata Tambelli, Daniela Altavilla, Cristina Trentini, Sara Panunzi, Mariella Stanca, Paola Aceto, Francesco Cardona, Carlo Lai
OBJECTIVES: The present study investigated the role of different emotions in the expression of cognitive and motor control abilities of children having Tourette's Syndrome (TS) compared to healthy controls. METHODS: The electroencephalography (EEG) activity of thirty-three children (mean age in final sample: TS (n = 10)=10.5±2.3; control (n = 10)=10.1±2.9) was recorded during a visual task consisting of four emotional face cues (anger, happiness, neutral and sadness) followed by a target in congruent or incongruent position with emotional cue...
January 24, 2018: World Journal of Biological Psychiatry
A Zarabla, S Ungania, A Cacciatore, A Maialetti, G Petreri, A Mengarelli, A Spadea, F Marchesi, D Renzi, Svitlana Gumenyuk, L Strigari, Marta Maschio
Cytosine arabinoside (Ara-C) is one of the key drugs for treating acute myeloid leukemia (AML). High intravenous doses may produce a number of central nervous system (CNS) toxicities and contribute to modifications in brain functional connectivity. sLORETA is a software used for localizing brain electrical activity and functional connectivity. The aim of this study was to apply sLORETA in the evaluation of possible effects of Ara-C on brain connectivity in patients with AML without CNS involvement. We studied eight patients with AML; four were administered standard doses of Ara-C while the other four received high doses...
October 2017: Functional Neurology
Soohyun Lee, Seunghwan Kim, Jee Hyun Choi
Equivalent dipole source localization is a well-established approach to localizing the electrical activity in electroencephalogram (EEG). So far, source localization has been used primarily in localizing the epileptic source in human epileptic patients. Currently, source localization techniques have been applied to account for localizing epileptic source among the epileptic patients. Here, we present the first application of source localization in the field of sleep spindle in mouse brain. The spatial distribution of cortical potential was obtained by high density EEG and then the anterior and posterior sleep spindles were classified based on the K-mean clustering algorithm...
December 2017: Experimental Neurobiology
Lina Zhou, Gaohua Wang, Huiling Wang
Despite a wide range of reports on depression-induced P300 changes, it is still debatable whether P300 can return to a pattern characteristic of healthy individuals following antidepressant treatment. Thus, the present study aims to compare P300 and its underlying neural activation in depressed patients before and after antidepressant treatment to explore the brain regions related to pathogenesis and to evaluate the prognosis after treatment. P300 was evoked by the oddball auditory paradigm and collected from 14 sex-matched, age-matched, and education level-matched patients and controls...
December 12, 2017: Neuroreport
Rinaldo Livio Perri, Marika Berchicci, Valentina Bianco, Donatella Spinelli, Francesco Di Russo
Using two independent electrical neuroimaging techniques (BESA and sLORETA), we tested a fMRI-seeded source modeling indicating that in visual discriminative tasks the anterior insula (aIns) participates in the generation of three prefrontal ERP components: the pN1 (at 115 ms), the pP1 (at 170 ms), and the pP2 (at 300 ms). This latter component represented the focus of the present study. Results showed that the pP2 had different activation profiles across hemispheres. The left aIns activity peaked at 420 ms (30 ms before the response) for both Go and No-go trials, that is independently from the ultimate choice (response or inhibition)...
November 9, 2017: Brain Structure & Function
Jayabal Velmurugan, Srikantan S Nagarajan, Narayanan Mariyappa, Shankar G Ravi, Kandavel Thennarasu, Ravindranadh C Mundlamuri, Kenchaiah Raghavendra, Rose Dawn Bharath, Jitender Saini, Arimappamagan Arivazhagan, Jamuna Rajan, Anita Mahadevan, Malla B Rao, Parthasarathy Satishchandra, Sanjib Sinha
OBJECTIVE: Specificity of ictal high-frequency oscillations (HFOs) in identifying epileptogenic abnormality is significant, compared to the spikes and interictal HFOs. The objectives of the study were to detect and to localize ictal HFOs by magnetoencephalography (MEG) for identifying the seizure onset zone (SOZ), evaluate the cortical excitability from preictal to ictal transition, and establish HFO concordance rates with other modalities and postsurgical resection. METHODS: Sixty-seven patients with drug-resistant epilepsy had at least 1 spontaneous seizure each during MEG acquisition, and analysis was carried out on 20 seizures from 20 patients...
November 7, 2017: Epilepsia
Xingwei An, Jinwen Wei, Shuang Liu, Dong Ming
EEG-based BCI (brain-computer-interface) speller, especially gaze-independent BCI speller, has become a hot topic in recent years. It provides direct spelling device by non-muscular method for people with severe motor impairments and with limited gaze movement. Brain needs to conduct both stimuli-driven and stimuli-related attention in fast presented BCI paradigms for such BCI speller applications. Few researchers studied the mechanism of brain response to such fast presented BCI applications. In this study, we compared the distribution of brain activation in visual, auditory, and audio-visual combined stimuli paradigms using sLORETA (standardized low-resolution brain electromagnetic tomography)...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Bin Hu, Juan Rao, Xiaowei Li, Tong Cao, Jianxiu Li, Dennis Majoe, Jürg Gutknecht
Major depressive disorders (MDD) exhibit cognitive dysfunction with respect to attention. The deficiencies in cognitive control of emotional information are associated with MDD as compared to healthy controls (HC). However, the brain mechanism underlying emotion that influences the attentional control in MDD necessitates further research. The present study explores the emotion-regulated cognitive competence in MDD at a dynamic attentional stage. Event-Related Potentials (ERPs) were recorded from 35 clinical MDD outpatients and matched HCs by applying a modified affective priming dot-probe paradigm, which consisted of various emotional facial expression pairs...
October 19, 2017: Scientific Reports
Maria Stein, Werner Fey, Thomas Koenig, Jacqueline Oehy, Franz Moggi
BACKGROUND: Most contemporary neuroscientific models of alcohol use disorders (AUD) incorporate an imbalance between enhanced cue reactivity, which results in a strong urge to consume, and the impaired inhibitory control of that urge. While these phenomena have been frequently investigated separately, studies involving both aspects and thus precisely investigating the postulated imbalance are rare. In this study, inhibition was investigated in an addiction-specific context and individual craving levels were also examined...
October 16, 2017: Alcoholism, Clinical and Experimental Research
Foroozan Karimzadeh, Mohammad Nami, Reza Boostani
The present study examined the relationship between the increment in cyclic alternating patterns (CAPs) in sleep electroencephalography and neurocognitive decline in obstructive Sleep Apnea Syndrome (OSAS) patients through source localization of the phase-A of CAPs. All-night polysomnographic recordings of 10 OSAS patients and 4 control subjects along with their cognitive profile using the Addenbrooke's Cognitive Examination (ACE) test were acquired. The neuropsychological assessment involved five key domains including attention and orientation, verbal fluency, memory, language and visuo-spatial skills...
2017: Journal of Integrative Neuroscience
Boris Yazmir, Miriam Reiner
Motor impairments come in different forms. One class of motor impairments, relates to accuracy of tracking a moving object, as, for instance, when chasing in an attempt to catch it. Here we look at neural signals associated with errors in tracking, and the implications for brain-computer-interfaces that target impairment-tailored rehabilitation. As a starting point, we characterized EEG signals evoked by tracking errors during continuous natural motion, in healthy participants. Participants played a virtual 3D, ecologically valid haptic tennis game, and had to track a moving tennis ball in order to hit and send the ball towards the opponent's court...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
Martin Rakusa, Pierpaolo Busan, Piero Paolo Battaglini, Janez Zidar
Simple imaginary movements activate similar cortical and subcortical areas to actual movements, chiefly in the sensory-motor network. However, only a few studies also examined the imagery of more skilful movements such as reaching. Ten volunteers performed reaching movements or imagined the same movements. EEG was simultaneously recorded and analysed with sLORETA, which compared the preparation for actual and imagined reaching with respect to their baseline and between tasks. Major differences between them were found at three time intervals after target presentation, always in favour of the actual reaching condition...
March 2018: Brain Topography
Pegah Khosropanah, Abdul Rahman Ramli, Kheng Seang Lim, Mohammad Hamiruce Marhaban, Anvarjon Ahmedov
EEG source localization is determining possible cortical sources of brain activities with scalp EEG. Generally, every step of the data processing sequence affects the accuracy of EEG source localization. In this paper, we introduce a fused multivariate empirical mode decomposing (MEMD) and inverse solution algorithm with an embedded unsupervised eye blink remover in order to localize the epileptogenic zone accurately. For this purpose, we constructed realistic forward models using MRI and boundary element method (BEM) for each patient to obtain results that are more realistic...
July 22, 2017: Biomedizinische Technik. Biomedical Engineering
Domonkos File, Bálint File, Flóra Bodnár, István Sulykos, Krisztina Kecskés-Kovács, István Czigler
The aim of our studies was to separate the effects of violating a sequential rule (genuine visual mismatch negativity; gvMMN) from the decreased activity in response to repeated stimuli (stimulus-specific adaptation; SSA) for simple and more complex stimuli. To accomplish this goal, different control procedures were applied with the aim of finding the correct control for vMMN studies. Event-related brain electric activity (ERPs) was measured in response to nonattended visual stimuli that were presented either in an oddball manner or in various control sequences...
October 2017: Attention, Perception & Psychophysics
Yuanjun Xie, Yuanyuan Xu, Chen Bian, Min Li
Although multisensory integration is an inherent component of functional brain organization, multisensory integration during working memory (WM) has attracted little attention. The present study investigated the neural properties underlying the multisensory integration of WM by comparing semantically related bimodal stimulus presentations with unimodal stimulus presentations and analysing the results using the standardized low-resolution brain electromagnetic tomography (sLORETA) source location approach. The results showed that the memory retrieval reaction times during congruent audiovisual conditions were faster than those during unisensory conditions...
July 11, 2017: Scientific Reports
Julien D Périard, Kevin De Pauw, Frank Zanow, Sébastien Racinais
AIM: Heat stress and hypoxia independently influence cerebrocortical activity and impair prolonged exercise performance. This study examined the relationship between electroencephalography (EEG) activity and self-paced exercise performance in control (CON, 18°C, 40% RH), hot (HOT, 35°C, 60%RH) and hypoxic (HYP, 18°C, 40%RH FiO2 : 0.145) conditions. METHODS: Eleven well-trained cyclists completed a 750 kJ cycling time trial in each condition on separate days in a counter-balanced order...
July 7, 2017: Acta Physiologica
D Cosandier-Rimélé, G Ramantani, J Zentner, A Schulze-Bonhage, M Dümpelmann
OBJECTIVE: Electrical source localization (ESL) deriving from scalp EEG and, in recent years, from intracranial EEG (iEEG), is an established method in epilepsy surgery workup. We aimed to validate the distributed ESL derived from scalp EEG and iEEG, particularly regarding the spatial extent of the source, using a realistic epileptic spike activity simulator. APPROACH: ESL was applied to the averaged scalp EEG and iEEG spikes of two patients with drug-resistant structural epilepsy...
October 2017: Journal of Neural Engineering
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