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https://www.readbyqxmd.com/read/29154695/an-evaluation-of-portable-wet-bulb-globe-temperature-monitor-accuracy
#1
Earl Cooper, Andrew Grundstein, Adam Rosen, Jessica Miles, Jupil Ko, Patrick Curry
CONTEXT:   Wet bulb globe temperature (WBGT) is the gold standard for assessing environmental heat stress during physical activity. Many manufacturers of commercially available instruments fail to report WBGT accuracy. OBJECTIVE:   To determine the accuracy of several commercially available WBGT monitors compared with a standardized reference device. DESIGN:   Observational study. SETTING:   Field test. PATIENTS OR OTHER PARTICIPANTS:   Six commercially available WBGT devices...
November 20, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/29152211/xenon-helium-gas-mixture-at-equimolar-concentration-of-37-5-protects-against-oxygen-and-glucose-deprivation-induced-injury-and-inhibits-tissue-plasminogen-activator
#2
Hélène N David, Benoit Haelewyn, Jean-Éric Blatteau, Jean-Jacques Risso, Nicolas Vallée, Jacques H Abraini
Xenon (Xe) is considered to be the golden standard neuroprotective gas. However, Xe has a higher molecular weight and lower thermal conductivity and specific heat than those of nitrogen, the main diluent of oxygen in air. These physical characteristics could impair or at least reduce the intrinsic neuroprotective action of Xe by increasing the patient's respiratory workload and body temperature. In contrast, helium (He) is a cost-efficient gas with a lower molecular weight and higher thermal conductivity and specific heat than those of nitrogen, but is far less potent than Xe...
July 2017: Medical Gas Research
https://www.readbyqxmd.com/read/29124059/evaluation-of-three-hydration-strategies-in-detection-dogs-working-in-a-hot-environment
#3
Cynthia M Otto, Elizabeth Hare, Jess L Nord, Shannon M Palermo, Kathleen M Kelsey, Tracy A Darling, Kasey Schmidt, Destiny Coleman
Physical activity in hot environments can increase the risk of heat stress or heat stroke in dogs. Heat tolerance is influenced by acclimatization to the environment, physical fitness, and hydration state. Three common strategies to promote hydration in working dogs are free access to water (W), oral electrolyte solutions (OESs), and administration of subcutaneous fluids (SQs). None of these methods have been compared for safety or efficacy in a working environment. In a cross-over design, seven vehicle-screening canines were randomly assigned to each of the three hydration strategies during working shifts at the Sarita, TX checkpoint...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29123835/ambulance-dispatches-to-schools-during-a-5-year-period-in-fukui-prefecture
#4
Yoshikazu Takinami, Shinji Maeda
Aim: To determine the characteristics and trends of medical emergencies during school activities by analyzing information provided by fire departments. Methods: During a 5-year period from January 2009 to December 2013, all nine fire departments in Fukui Prefecture handled 850 emergencies at schools. We investigated the 850 cases with the age range of 0-63 years. Results: It was found that 21.5% of ambulance dispatches to schools were on weekends and there were more dispatches for non-faculty members of all age groups on weekends than on weekdays...
January 2017: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29101264/increased-coronary-heart-disease-and-stroke-hospitalisations-from-ambient-temperatures-in-ontario
#5
Li Bai, Qiongsi Li, Jun Wang, Eric Lavigne, Antonio Gasparrini, Ray Copes, Abderrahmane Yagouti, Richard T Burnett, Mark S Goldberg, Sabit Cakmak, Hong Chen
OBJECTIVE: To assess the associations between ambient temperatures and hospitalisations for coronary heart disease (CHD) and stroke. METHODS: Our study comprised all residents living in Ontario, Canada, 1996-2013. For each of 14 health regions, we fitted a distributed lag non-linear model to estimate the cold and heat effects on hospitalisations from CHD, acute myocardial infarction (AMI), stroke and ischaemic stroke, respectively. These effects were pooled using a multivariate meta-analysis...
November 3, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29098600/a-model-based-on-the-pennes-bioheat-transfer-equation-is-valid-in-normal-brain-tissue-but-not-brain-tissue-suffering-focal-ischaemia
#6
Thomas Lillicrap, Murat Tahtalı, Andrew Neely, Xiaofei Wang, Andrew Bivard, Christian Lueck
Ischaemic stroke is a major public health issue in both developed and developing nations. Hypothermia is believed to be neuroprotective in cerebral ischaemia. Conversely, elevated brain temperature is associated with poor outcome after ischaemic stroke. Mechanisms of heat exchange in normally-perfused brain are relatively well understood, but these mechanisms have not been studied as extensively during focal cerebral ischaemia. A finite element model (FEM) of heat exchange during focal ischaemia in the human brain was developed, based on the Pennes bioheat equation...
November 2, 2017: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/29095276/outcome-and-risk-factors-associated-with-extent-of-central-nervous-system-injury-due-to-exertional-heat-stroke
#7
Mengmeng Yang, Zhi Li, Yan Zhao, Feihu Zhou, Yu Zhang, Jingli Gao, Ting Yin, Xin Hu, Zhi Mao, Jianguo Xiao, Li Wang, Chao Liu, Liqiong Ma, Zhihao Yuan, Jianfei Lv, Haoliang Shen, Peter C Hou, Hongjun Kang
To explore the relationship between the extent of central nervous system (CNS) injury and patient outcomes meanwhile research the potential risk factors associated with neurologic sequelae. In this retrospective cohort study, we analyzed data from 117 consecutive patients (86 survivors, 31 nonsurvivors) with exertional heat stroke (EHS) who had been admitted to intensive care unit (ICU) at 48 Chinese hospitals between April 2003 and July 2015. Extent of CNS injury was dichotomized according to Glasgow coma scale (GCS) score (severe 3-8, not severe 9-15)...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29094038/intracorporeal-heat-distribution-from-fully-implantable-energy-sources-for-mechanical-circulatory-support-a-computational-proof-of-concept-study
#8
Jacopo Biasetti, Aliaksei Pustavoitau, Pier Giorgio Spazzini
Mechanical circulatory support devices, such as total artificial hearts and left ventricular assist devices, rely on external energy sources for their continuous operation. Clinically approved power supplies rely on percutaneous cables connecting an external energy source to the implanted device with the associated risk of infections. One alternative, investigated in the 70s and 80s, employs a fully implanted nuclear power source. The heat generated by the nuclear decay can be converted into electricity to power circulatory support devices...
2017: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/29084063/central-vertigo
#9
Jeong-Yoon Choi, Seung-Han Lee, Ji-Soo Kim
PURPOSE OF REVIEW: This review considers recent advances in central vertigo in terms of clinical and laboratory features and pathophysiology. RECENT FINDINGS: Strokes presenting dizziness-vertigo are more likely to be associated with a misdiagnosis in the emergency setting. The risk of future strokes after discharge is higher in patients diagnosed with peripheral vertigo than in control patients. Strokes and transient ischemic attacks account for one-quarter of acute transient vestibular syndrome...
October 27, 2017: Current Opinion in Neurology
https://www.readbyqxmd.com/read/29071978/-effect-of-xingnao-kaiqiao-zhenfa-acupuncture-technique-for-restoring-consciousness-combined-with-rehabilitation-training-on-nerve-repair-and-expression-of-growth-associated-protein-43-of-peri-ischemic-cortex-in-ischemic-stroke-rats
#10
Lei Xu, Xing-Zhou Yan, Zhen-Yu Li, Xiao-Fang Cao, Min Wang
OBJECTIVE: To observe the effect of "Xingnao Kaiqiao Zhenfa" (acupuncture technique for restoring consciousness) combined with enriched rehabilitation training on motor function and expression of growth-associated protein-43 (GAP-43) of peri-ischemic cortex in ischemic stroke rats, so as to investigate its mechanism underlying improvement of ischemic stroke. METHODS: SD rats were randomly divided into sham operation, model, rehabilitation and comprehensive rehabilitation groups, which were further divided into 3 time-points:7, 14 and 21 d (n=6 in each)...
June 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29066054/the-validity-of-the-heat-tolerance-test-in-prediction-of-recurrent-exertional-heat-illness-events
#11
Haggai Schermann, Yuval Heled, Chen Fleischmann, Itay Ketko, Nathan Schiffmann, Yoram Epstein, Ran Yanovich
OBJECTIVES: Heat-tolerance-testing (HTT) protocol is used as a screening test for secondary prevention of exertional heat illness (EHI) in the military. Subjects whose test results are positive (heat-intolerant, HI) are presumed to be at higher risk of repeated EHI events than heat-tolerant subjects (HT) and are therefore prevented from return to combat duty, but may return to unsupervised recreational activity. Our aim was to determine, whether HTT results predict the risk of repeated episodes of exertional heat illness (EHI)...
October 12, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29057127/heat-stroke-a-medical-emergency-appearing-in-new-regions
#12
Sofie Søndergaard Mørch, Johnny Dohn Holmgren Andersen, Morten Heiberg Bestle
Heat stroke is an acute, life-threatening emergency characterized clinically by elevated body temperature and central nervous system dysfunction. Early recognition and treatment including aggressive cooling and management of life-threatening systemic complications are essential to reduce morbidity and mortality. This case report describes two Danish patients diagnosed with heat stroke syndrome during a heat wave in the summer of 2014. Both patients were morbidly obese and had several predisposing illnesses...
2017: Case Reports in Critical Care
https://www.readbyqxmd.com/read/29044895/surveying-all-public-drinking-water-fountains-in-a-city-outdoor-field-observations-and-google-street-view
#13
Nick Wilson, Louise Signal, George Thomson
OBJECTIVE: Drinking fountains are a public amenity that may help counter the obesogenic environment (sugary beverages) and reduce the risk of heat stroke during heat waves. As a case study, we aimed to survey all public fountains in a city: Wellington, New Zealand, and to determine the utility of Google Street View in studying drinking fountains. METHODS: Using a sample of all public drinking fountains in a City Council map, a field observer assessed their exact location and tap functionality, and photographed them...
October 18, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/29024265/effectiveness-of-a-handmade-new-carotid-catheter-in-transradial-carotid-angiography-a-comparison-with-conventional-multipurpose-catheters
#14
Yakup Balaban
OBJECTIVE: The incidence and severity of carotid atherosclerosis increases in proportion with coronary artery disease and its severity. A special catheter specifically used for transradial carotid angiography has not yet been marketed. In this study, we investigate the feasibility and safety of our carotid catheter, which was made by reshaping currently available catheters. METHODS: Between 2010 and 2017, a total of 921 patients with indications for carotid angiography were identified after angiographic examinations and included in the study...
October 11, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29020197/sickle-cell-trait-and-heat-injury-among-u-s-army-soldiers
#15
D Alan Nelson, Patricia A Deuster, Francis G O'Connor, Lianne M Kurina
There is concern that sickle cell trait increases risk of exertional collapse, a primary cause of which is heat injury. However, no population-based studies among active individuals have addressed this, representing a critical evidence gap. We conducted a retrospective cohort study of sickle cell trait-tested African American soldiers on active-duty in the U.S. Army anytime between January 2011 and December 2014. Using Cox proportional hazards models and adjusting for demographic and medical factors, we observed no significant associations between sickle cell trait and either mild heat injury (hazard ratio (HR), 1...
August 17, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28992693/pinpoint-diagnostic-kit-for-heat-stroke-by-monitoring-lysosomal-ph
#16
Ying Wen, Weijie Zhang, Tao Liu, Fangjun Huo, Caixia Yin
Heat stroke is one of the most serious causes of mortality. To prevent the situation, it is fundamental to research the mechanism of heat cytotoxicity. The preliminary results revealed that heat stroke and the change of lysosome acidity had some certain correlation. To further clarify their relationship, herein, we report a highly selective and sensitive fluorescence probe (NT1) for turn-on sensing of the pH value. NT2 was synthesized as control compound. Compared to NT2, NT1 showed accurate lysosome target ability...
November 7, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28985560/ferroptosis-a-regulated-cell-death-nexus-linking-metabolism-redox-biology-and-disease
#17
REVIEW
Brent R Stockwell, José Pedro Friedmann Angeli, Hülya Bayir, Ashley I Bush, Marcus Conrad, Scott J Dixon, Simone Fulda, Sergio Gascón, Stavroula K Hatzios, Valerian E Kagan, Kay Noel, Xuejun Jiang, Andreas Linkermann, Maureen E Murphy, Michael Overholtzer, Atsushi Oyagi, Gabriela C Pagnussat, Jason Park, Qitao Ran, Craig S Rosenfeld, Konstantin Salnikow, Daolin Tang, Frank M Torti, Suzy V Torti, Shinya Toyokuni, K A Woerpel, Donna D Zhang
Ferroptosis is a form of regulated cell death characterized by the iron-dependent accumulation of lipid hydroperoxides to lethal levels. Emerging evidence suggests that ferroptosis represents an ancient vulnerability caused by the incorporation of polyunsaturated fatty acids into cellular membranes, and cells have developed complex systems that exploit and defend against this vulnerability in different contexts. The sensitivity to ferroptosis is tightly linked to numerous biological processes, including amino acid, iron, and polyunsaturated fatty acid metabolism, and the biosynthesis of glutathione, phospholipids, NADPH, and coenzyme Q10...
October 5, 2017: Cell
https://www.readbyqxmd.com/read/28978590/liver-transplantation-for-non-exertional-heat-stroke-related-acute-liver-failure
#18
Sandra Coenen, Khe Tran, Jubi de Haan, Rob de Man
Heat stroke is a life-threatening condition characterised by hyperthermia leading to multiple organ dysfunction. Acute liver failure is a rare and potentially fatal consequence of heat stroke. Management of heat stroke is mainly supportive but liver transplantation can be considered as the treatment of acute liver failure in heat stroke. However, literature on liver transplantation as a treatment for acute liver failure in heat stroke is scarce. Until now, no cases of liver transplantation for acute liver failure in non-exertional heat stroke have been reported...
October 4, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28964966/ambient-temperature-and-added-heat-wave-effects-on-hospitalizations-in-california-from-1999-to-2009
#19
Toki Sherbakov, Brian Malig, Kristen Guirguis, Alexander Gershunov, Rupa Basu
Investigators have examined how heat waves or incremental changes in temperature affect health outcomes, but few have examined both simultaneously. We utilized distributed lag nonlinear models (DLNM) to explore temperature associations and evaluate possible added heat wave effects on hospitalizations in 16 climate zones throughout California from May through October 1999-2009. We define heat waves as a period when daily mean temperatures were above the zone- and month-specific 95th percentile for at least two consecutive days...
September 28, 2017: Environmental Research
https://www.readbyqxmd.com/read/28956577/high-strain-actuation-liquid-crystal-elastomers-via-modulation-of-mesophase-structure
#20
Mohand O Saed, Ross H Volpe, Nicholas A Traugutt, Rayshan Visvanathan, Noel A Clark, Christopher M Yakacki
Control of the mesophase in liquid crystalline elastomers (LCEs) is a critical aspect in harnessing their unique stimuli-responsive properties. Few studies have compared nematic and smectic main-chain LCEs in a direct way. Traditionally, it is believed that the mesogen core and synthetic route determines the phase behavior. In this study, we hypothesized that tuning the LC phases in main-chain LCE systems can be achieved by varying the spacer length while maintaining the same mesogen (RM257). By increasing the length of dithiol alkyl spacers containing two to eleven carbons along the spacer backbone (C2 to C11), we can modulate the mesophase from nematic to smectic, tailor the nematic to isotropic transition temperature between 90 and 140 °C, and increase the average work capacity from 128 to 262 kJ m(-3)...
October 25, 2017: Soft Matter
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