Read by QxMD icon Read


Meng Liao, Haoxing Zhao, Longqian Liu, Qian Li, Yun Dai, Yudong Zhang, Yifeng Zhou
Perceptual learning is considered a potential treatment for amblyopia even in adult patients who have progressed beyond the critical period of visual development because adult amblyopes retain sufficient visual plasticity. When perceptual learning is performed with the correction of high-order aberrations (HOAs), a greater degree of neural plasticity is present in normal adults and those with highly aberrated keratoconic eyes. Because amblyopic eyes show more severe HOAs than normal eyes, it is interesting to study the effects of HOA-corrected visual perceptual learning in amblyopia...
October 18, 2016: Scientific Reports
Ömür Ö Uçakhan, Betül Bayraktutar
PURPOSE: To evaluate the morphological features of the corneal limbus as measured by in vivo confocal microscopy (IVCM) following standard and accelerated corneal collagen cross-linking (CXL) for keratoconus. METHODS: Patients with progressive keratoconus scheduled to undergo standard CXL (group 1; 31 patients, 3 mW/cm, 370 nm, 30 minutes), or accelerated CXL (group 2; 20 patients, 9 mW/cm, 370 nm, 10 minutes) in the worse eye were included in this prospective study...
October 5, 2016: Cornea
Fateme Alipour, Mojgan Letafatnejad, Amir Hooshang Beheshtnejad, Seyed-Farzad Mohammadi, Seyed Reza Ghaffary, Narges Hassanpoor, Mehdi Yaseri
Purpose. To evaluate the difference in biomechanical properties between contact lens induced corneal warpage and normal and keratoconic eyes. Method. Prospective observational case control study, where 94 eyes of 47 warpage suspicious and 46 eyes of 23 keratoconic patients were included. Warpage suspected cases were followed until a definite diagnosis was made (warpage, normal, or keratoconus). Results. 44 eyes of 22 patients had contact lens related corneal warpage. 46 eyes of 23 people were diagnosed as nonwarpage normal eyes...
2016: Journal of Ophthalmology
Carmen Mendez-Hernandez, Paula Arribas-Pardo, Ricardo Cuiña-Sardiña, Cristina Fernandez-Perez, Rosalia Mendez-Fernandez, Federico Saenz-Frances, Jose M Benitez-Del-Castillo, Julian Garcia-Feijoo
PURPOSE: To compare intraocular pressure (IOP) measurements made using 5 tonometers in keratoconic eyes with and without intrastromal corneal ring segments. METHODS AND PATIENTS: This was an observational case series study. A total of 147 eyes of 147 patients with keratoconus, 74 of which had undergone corneal ring segment placement, were prospectively evaluated. IOP was measured using the tonometers Tonopen XL, Pascal dynamic contour tonometer, iCare Pro, ocular response analyzer (ORA), and Goldmann applanation (GAT) in random order...
September 21, 2016: Journal of Glaucoma
S S Wei, Y Li, J Li, J G Liu, L Ye, Y Q Wan, J Li, J Du
Objective: To compare the corneal biomechanical properties of keratoconic and normal eyes, and to explore the changing characteristics in keratoconic eyes. Methods: Case-control study. Thirty-two keratoconic subjects(41 eyes)and 41 subjects(41 eyes)with normal corneas were enrolled in this study. Scheimpflug noncontact tonometry(Corvis ST)was performed to measure the length of Appl 1(1st A length), velocity of Appl 1(Vin), length of Appl 2(2nd A length), velocity of Appl 2(Vout), deformation amplitude(DA), peak distance, and radius...
September 11, 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
Mehrdad Mohammadpour, Kazem Mohammad, Nasser Karimi
PURPOSE: To evaluate the agreement among Pentacam, Orbscan and ultrasound (US) pachymetry for measurement of central corneal thickness (CCT) in thin corneas with normal topographic pattern. METHODS: We included 88 eyes of 44 refractive surgery candidates with thinnest pachymetric readings of 500 micrometers (μm) or less on Orbscan, a normal topographic pattern, no sign of keratoconus, and best corrected visual acuity (BCVA) of 20/20. Pentacam, Orbscan and US were performed in one session by the same examiner...
July 2016: Journal of Ophthalmic & Vision Research
Xiangjun Chen, Aleksandar Stojanovic, Xiaorui Wang, Jing Liang, Di Hu, Tor Paaske Utheim
PURPOSE: To evaluate corneal epithelial remodeling after topography-guided transepithelial photorefractive keratectomy (PRK) combined with corneal collagen cross-linking (CXL) in the treatment of keratoconus. METHODS: Retrospective analysis of the epithelial thickness distribution changes in 53 keratoconic eyes of 44 patients. Manifest refraction, maximum (Kmax) and minimum (Kmin) keratometry obtained by Placido topography, corneal irregularity index (IRI) measured by Scheimpflug topography, and the epithelial thickness profile over the central 5-mm zone obtained by anterior-segment spectral domain optical coherence tomography (SD-OCT) were evaluated preoperatively and at 1 to 3, 3 to 6, and more than 6 months postoperatively...
August 1, 2016: Journal of Refractive Surgery
Kate Grieve, Cristina Georgeon, Felipe Andreiuolo, Marie Borderie, Djida Ghoubay, Josette Rault, Vincent M Borderie
PURPOSE: To search for gold-standard histology indicators using alternative imaging modalities in keratoconic corneas. METHODS: Prospective observational case-control study. Fourteen keratoconic corneas and 20 normal corneas (10 in vivo healthy subjects and 10 ex vivo donor corneas) were examined. Images of corneas were taken by spectral domain optical coherence tomography (SD-OCT) and in vivo confocal microscopy (IVCM) before keratoplasty. The same removed corneal buttons were imaged after keratoplasty with full-field optical coherence microscopy (FFOCM) and then fixed and sent for histology...
August 25, 2016: Cornea
Sujin Kim, Jong Soo Lee, Young Kee Park, Seung Uk Lee, Young Min Park, Jong Heon Lee, Ji-Eun Lee
BACKGROUND: The aim was to evaluate the clinical results of fitting MSD miniscleral contact lenses (MSD; Happy Vision Corp, Anyang, Korea) in Korean patients with keratoconus. METHODS: This report presents a retrospective case review of 38 keratoconic patients fitted with MSD lenses. Visual acuity, comfort, mean wear time, final lens parameters, relationships between sagittal depth and topographic indices, success rate with the first lens ordered and adverse events were documented...
August 23, 2016: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
Sara Ortiz-Toquero, Virginia Zuñiga, Guadalupe Rodriguez, Victoria de Juan, Raul Martin
PURPOSE: To compare the anterior corneal measurements between Placido-based topography and dual-Scheimpflug topography in healthy and keratoconus eyes. SETTING: Optometry Research Group, Instituto Universitario de Oftalmobiología Aplicada, University of Valladolid, Valladolid, Spain. DESIGN: Comparative case series. METHODS: The mean simulated keratometry (K), flat K, steep K, astigmatism power, corneal astigmatism axis, J0, J45, maximum corneal power point, and white-to-white (WTW) distance were collected and compared between healthy eyes and keratoconus eyes...
August 2016: Journal of Cataract and Refractive Surgery
Alain Saad, Damien Gatinel
PURPOSE: To evaluate the accuracy of a new objective method based on Placido disk-derived data for the detection of eyes at risk of ectasia. METHODS: One hundred nineteen eyes of 176 patients were included and separated into two groups, normal and forme fruste keratoconus (FFKC), using automated corneal classification software. Normal eyes (n = 114) were classified as negative for keratoconus and keratoconus suspect and had undergone LASIK with unremarkable follow-up for 4 years...
August 1, 2016: Journal of Refractive Surgery
Luis Fernández-Vega Cueto, Carlos Lisa, Aranzazu Poo-López, David Madrid-Costa, Jesús Merayo-Lloves, Jose F Alfonso
PURPOSE: To assess the efficacy outcomes of implanting intrastromal corneal ring segments (ICRS) to correct paracentral keratoconus. METHODS: Four hundred nine eyes with paracentral keratoconus, in which the differences between the axes of refractive cylinder and the corneal flattest meridian and the comatic aberration map were less than 30 degrees, were evaluated before and after the implantation of Ferrara-type ICRS. Snellen uncorrected and best-corrected distance visual acuity, residual refractive errors analyzed with vector analysis, and the root mean square for corneal coma-like aberration for a pupil size of 4...
November 2016: Cornea
Raffaella Mercatelli, Fulvio Ratto, Francesca Rossi, Francesca Tatini, Luca Menabuoni, Alex Malandrini, Riccardo Nicoletti, Roberto Pini, Francesco Saverio Pavone, Riccardo Cicchi
Keratoconus is an eye disorder that causes the cornea to take an abnormal conical shape, thus impairing its refractive functions and causing blindness. The late diagnosis of keratoconus is among the principal reasons for corneal surgical transplantation. This pathology is characterized by a reduced corneal stiffness in the region immediately below Bowman's membrane, probably due to a different lamellar organization, as suggested by previous studies. Here, the lamellar organization in this corneal region is characterized in three dimensions by means of second-harmonic generation (SHG) microscopy...
July 29, 2016: Journal of Biophotonics
Engy Mohamed Mostafa
The purpose of this study was to compare the anterior and posterior elevation measurements using different reference surfaces (spheric, aspheric, and aspherotoric) with Scheimpflug-Placido topography in simple myopic and keratoconus patients. 600 eyes of 600 patients undergoing screening for keratorefractive surgery (500 simple myopic, 100 keratoconus stage 1 and 2) in Sohag refractive center, Egypt, were examined by Scheimpflug-Placido topography (Sirius, CSO, Italy) for both the anterior and posterior corneal elevation maps using the spheric, aspheric, and aspherotoric reference surfaces...
July 28, 2016: International Ophthalmology
Soundaram MeenakshiSundaram, Aalia Rasool Sufi, N Venkatesh Prajna, Jeremy D Keenan
IMPORTANCE: In vivo confocal microscopy could be useful in cases of fungal or acanthamoeba keratitis to determine the depth of infectious elements, but its accuracy in determining corneal thickness relative to more traditional techniques has not been well characterized. OBSERVATIONS: In this cross-sectional observational case series, central corneal thickness was determined by in vivo confocal microscopy, ultrasonic pachymetry, and Scheimpflug topography in 47 normal corneas and 23 keratoconic corneas from November 2014 to July 2015...
September 1, 2016: JAMA Ophthalmology
Somayeh Radaie-Moghadam, Hassan Hashemi, Ebrahim Jafarzadehpur, Abbas Ali Yekta, Mehdi Khabazkhoob
PURPOSE: To determine the effect of using toric soft contact lenses on corneal biomechanical properties. METHODS: We enrolled 33 healthy patients with mean age of 23.18 ± 4.06 and minimal cylinder power of 1 D (-1.98 ± 0.808 SD) and negative history of contact lens use; keratoconic patients were excluded from the study. Toric soft contact lenses (BIOFINITY, Comfilcon A, Coopervision, Southampton, UK) were fitted in all participants. The Ocular Response Analyzer (Reichert Ophthalmic Instruments, Depew, New York, USA) was used to measure corneal hysteresis (CH), corneal resistance factor (CRF), and the Pentacam HR (Oculus, Inc...
April 2016: Journal of Ophthalmic & Vision Research
Fatih Özcura, Nilgün Yıldırım, Emre Tambova, Afsun Şahin
PURPOSE: To compare the intraocular pressure (IOP) measurements obtained with the rebound tonometry (RT), dynamic contour tonometry (DCT) and Goldmann applanation tonometry (GAT) in keratoconic corneas and to investigate the effects of central corneal thickness (CCT) and corneal radius of curvature (CR) on IOP measurements. METHODS: Sixty-three eyes of 63 keratoconus patients were enrolled in this cross-sectional study. IOP was measured on each subject always in the same order, ICare RT-Pascal DCT-GAT, after a minimum interval of 10min between measurements...
July 8, 2016: Journal of Optometry
S Catalan, L Cadarso, F Esteves, J Salgado-Borges, M Lopez, C Cadarso
Purpose. To compare the characteristics of asymmetric keratoconic eyes and normal eyes by Fourier domain optical coherence tomography (OCT) corneal mapping. Methods. Retrospective corneal and epithelial thickness OCT data for 74 patients were compared in three groups of eyes: keratoconic (n = 22) and normal fellow eyes (n = 22) in patients with asymmetric keratoconus and normal eyes (n = 104) in healthy subjects. Areas under the curve (AUC) of receiver operator characteristic (ROC) curves for each variable were compared across groups to indicate their discrimination capacity...
2016: Journal of Ophthalmology
Charles W McMonnies
BACKGROUND: Eye rubbing is commonly associated with keratoconus and may contribute to disease onset and progression. Verbal counselling to avoid rubbing may not be successful and adverse consequences of rubbing, which occurs on contact lens removal may be more serious. This study examines the prevalence of 'removal-relief' rubbing and its potential consequences. METHODS: Rubbing histories were recorded for contact lens wearing normal and keratoconic patients as well as for normal non-contact lens wearers...
July 2016: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
Enric Mas-Aixala, Joan Gispets, Núria Lupón, Genís Cardona
PURPOSE: To analyse, describe and test diverse corneal and anterior segment parameters in normal and keratoconic eyes to better understand the geometry of the keratoconic cornea. METHOD: 44 eyes from 44 keratoconic patients and 44 eyes from 44 healthy patients were included in the study. The Pentacam System was used for the analysis of the anterior segment parameters. New ad-hoc parameters were defined by measuring the distances on the Scheimpflug image at the horizontal diameter, with chamber depth now comprising of two distinctive distances: corneal sagittal depth and the distance from the endpoint of this segment to the anterior surface of the lens (DL)...
June 1, 2016: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"