keyword
MENU ▼
Read by QxMD icon Read
search

Keratocone

keyword
https://www.readbyqxmd.com/read/28714595/telocytes-in-normal-and-keratoconic-human-cornea-an-immunohistochemical-and-transmission-electron-microscopy-study
#1
Mirca Marini, Rita Mencucci, Irene Rosa, Eleonora Favuzza, Daniele Guasti, Lidia Ibba-Manneschi, Mirko Manetti
Telocytes (TC) are typically defined as cells with telopodes by their ultrastructural features. Their presence was reported in the interstitium of various organs in vertebrates, including humans. However, no study has yet described the presence of TC in the human eye and in particular, within the stromal compartment of the cornea. To address this issue, samples of normal and pathologic (keratoconic) human corneas were tested by immunohistochemistry for CD34, platelet-derived growth factor receptor α (PDGFRα) and c-kit/CD117 or examined by transmission electron microscopy...
July 17, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28704318/interrelationships-between-3-keratoconic-cone-parameters
#2
Kyaw L Tu, Abdo K Tourkmani, Singaram Srinivas
PURPOSE: To find out the interrelationships between 3 parameters of the keratoconic cone. METHODS: A total of 101 keratoconic eyes of 58 patients were included in this retrospective case series study. A complete eye examination was performed. Kmax (K) and pachymetry at the thinnest point (T) were obtained from the Pentacam tomographer. The vertex to thinnest pachymetry distance (D for decentration) was calculated using trigonometry. Pearson correlation coefficients between T and D, between T and K, and between D and K were calculated...
July 11, 2017: Cornea
https://www.readbyqxmd.com/read/28702953/characteristics-and-survey-of-keratoconic-contact-lens-wearers-who-are-lost-to-follow-up
#3
Martyn Ha Russell, Sabera Yusuf, Azita Rajai
No abstract text is available yet for this article.
July 12, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28687218/keratoconus-screening-indices-and-their-diagnostic-ability-to-distinguish-normal-from-ectatic-corneas
#4
Rohit Shetty, Harsha Rao, Pooja Khamar, Kanchan Sainani, Krishnapoojita Vunnava, Chaitra Jayadev, Luci Kaweri
PURPOSE: To compare the diagnostic ability of three Scheimpflug devices in differentiating normal from ectatic corneas. DESIGN: Comparison of diagnostic instrument accuracy METHODS: This study included 42 normal eyes, 37 subclinical and 51 keratoconic eyes, seen in a tertiary eye care institute. Keratoconus-screening indices were evaluated using the Pentacam, Galilei and Sirius. Sensitivity, specificity and area under receiver operating characteristic curve (AUC) were calculated...
July 4, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28681909/medium-to-long-term-results-of-corneal-cross-linking-for-keratoconus-using-phototherapeutic-keratectomy-for-epithelial-removal-and-partial-stromal-ablation
#5
Xiangjun Chen, Aleksandar Stojanovic, Yangyang Xu, Wen Zhou, Sten Raeder, Sam Enayati, Tor Paaske Utheim
PURPOSE: To evaluate the medium- to long-term outcomes of corneal cross-linking in treatment of keratoconus using transepithelial phototherapeutic keratectomy (PTK-CXL) for epithelial removal and partial stromal ablation to stabilize the cornea, reduce corneal irregularity, and improve corrected vision. METHODS: Retrospective analysis of 46 keratoconic eyes that underwent PTK-CXL. Corrected distance visual acuity (CDVA), manifest refraction, steep and flat simulated keratometry (Kmax and Kmin), corneal irregularity index (IRI), corneal higher order aberrations (HOAs), epithelial thickness profile, and corneal biomechanical characteristics were evaluated preoperatively and postoperatively...
July 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28647782/ocular-corneal-and-internal-aberrations-in-eyes-with-keratoconus-forme-fruste-keratoconus-and-healthy-eyes
#6
Mohammad Naderan, Ali Jahanrad, Mahgol Farjadnia
PURPOSE: The purpose of this study is to evaluate ocular, corneal, and internal aberration parameters in eyes with keratoconus (KC), forme fruste keratoconus (FFKC), and normal eyes. METHOD: In a prospective study, one eye of 110 patients with KC, 60 FFKC patients, and 150 healthy participants was evaluated using OPD-Scan II. Ocular, corneal, and internal higher-order aberrations were measured through a sixth-order Zernike polynomial decomposition. Receiver operating characteristic analysis was performed to evaluate the diagnostic ability of the aberration parameters in discriminating KC and FFKC from normal eyes...
June 24, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28646439/alterations-in-contact-lens-fitting-parameters-following-cross-linking-in-keratoconus-patients-of-indian-ethnicity
#7
Kirti Singh, Mainak Bhattacharyya, Ritu Arora, Sonal Dangda, Ankush Mutreja
BACKGROUND: Most studies have either excluded patients using contact lens or not taken their effect while analyzing post-collagen cross-linkage (CXL) changes. This study aims to study impact of CXL on lens fit in both quantitative and qualitative manner. OBJECTIVE: To evaluate changes in CL fit post-CXL and to correlate these changes with alterations in corneal topographic parameters. STUDY DESIGN: Prospective intervention study on 20 keratoconic eyes of 14 patients (age > 18 years), with mean follow-up of 6 months...
June 23, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28626821/mesopic-visual-quality-after-accelerated-corneal-cross-linking-a-12-month-follow-up-study
#8
Hassan Hashemi, Soheila Asgari
PURPOSE: To determine the 1-year changes of mesopic higher order aberrations (HOAs) and contrast sensitivity (CS) after accelerated corneal cross linking (CXL) in progressive keratoconus. METHODS: In this prospective case series, 70 eyes of 62 keratoconic patients underwent accelerated CXL (18 mW/cm(2), 5 min). HOAs and CS were measured using the OPD Scan III and CSV-1000 CS test charts under mesopic conditions before and 6 and 12 months after CXL. RESULTS: At 1 year, logarithmic mesopic CS in spatial frequencies of 3, 6, 12, and 18 cycles per degree (CPD) had increased by 0...
June 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28620708/validation-of-fourier-analysis-of-videokeratographic-data
#9
Haris Sideroudi, Georgios Labiris, Fienke Ditzel, Efi Tsaragli, Kimonas Georgatzoglou, Haralampos Siganos, Vassilios Kozobolis
PURPOSE: The aim was to assess the repeatability of Fourier transfom analysis of videokeratographic data using Pentacam in normal (CG), keratoconic (KC) and post-CXL (CXL) corneas. METHODS: This was a prospective, clinic-based, observational study. One randomly selected eye from all study participants was included in the analysis: 62 normal eyes (CG group), 33 keratoconus eyes (KC group), while 34 eyes, which had already received CXL treatment, formed the CXL group...
June 15, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28617726/comparative-analysis-of-peripheral-corneal-geometry-in-health-and-keratoconus
#10
Enric Mas-Aixala, Joan Gispets, Núria Lupón, Genís Cardona
OBJECTIVES: To describe and compare corneal peripheral angles in normal and keratoconic eyes, to gain a better understanding of the topography of the periphery of the cornea in keratoconus and assist practitioners in the selection and fitting of large diameter contact lenses. METHODS: Eighty-eight eyes were included in the study, divided into three groups: healthy (A0, 28 eyes), keratoconus at stage I according to the Amsler-Krumeich classification (AI, 33 eyes) and keratoconus at stages II to IV (AII, 27 eyes)...
June 14, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28604983/visual-outcomes-of-the-second-eye-in-keratoconic-patients-who-have-a-corneal-graft-in-the-first-eye-analysis-at-12-years
#11
Anne-Sophie Gauthier, Marie Friot, Marc Puyraveau, Thibaud Garcin, Maher Saleh, Phillipe Gain, Bernard Delbosc
PURPOSE: To analyze demographic, clinical, and keratometric outcomes of the second eye in keratoconic patients when the first eye has already been grafted, initially and finally at 12 years. METHODS: Retrospective analysis of initial and 12 years visual and keratometric outcomes of the second eye in keratoconic patients when the first one has already been grafted. RESULTS: A total of 107 patients were included: 66 patients were analyzed at the beginning of the follow-up and at 12 years...
June 10, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28593180/surgical-management-of-spontaneous-late-onset-descemet-membrane-detachment-after-penetrating-keratoplasty-for-keratoconus-a-case-report
#12
Myrsini Petrelli, Konstantinos Oikonomakis, Konstantinos Andreanos, Andreas Mouchtouris, Ilias Georgalas, George Kymionis
BACKGROUND: To report a surgical method for treating corneal oedema in a case of late-onset Descemet membrane detachment after penetrating keratoplasty. CASE PRESENTATION: A 55-year old patient presented with sudden visual loss in his left eye 28 years after penetrating keratoplasty for keratoconus. Slit-lamp biomicroscopy revealed a distortion of the corneal graft anatomy with protrusion of the graft and peripheral thinning and steepening in the residual host tissue, accompanied by corneal graft oedema...
2017: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/28591280/keratoconus-progression-is-not-inhibited-by-reducing-eyelid-muscular-force-with-botulinum-toxin-a-treatment-a-randomized-trial
#13
Adimara da Candelaria Renesto, Teissy Hentona Osaki, Midori Hentona Osaki, Flávio E Hirai, Mauro Campos
Purpose: To evaluate whether reducing eyelid muscular force through the administration of botulinum toxin type A (BTX-A) to the orbicularis oculi muscles of patients with keratoconus affected corneal parameters indicative of disease progression. Methods: In this prospective parallel randomized clinical trial, 40 eyes of 40 patients with keratoconus were randomized into equally sized control and BTX-A groups. Patients in the BTX-A group received subcutaneous BTX-A injections into the orbicularis muscle...
March 2017: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28540006/office-based-relaxing-incision-procedure-for-correction-of-astigmatism-after-deep-anterior-lamellar-keratoplasty
#14
Mohammad Ali Javadi, Sepehr Feizi, Firooz Mirbabaee, Yousef Fekri
PURPOSE: To report the outcomes of a simple and effective office-based procedure for the correction of astigmatism after deep anterior lamellar keratoplasty (DALK). METHODS: This study enrolled 24 consecutive keratoconic eyes that developed an intolerable amount of graft astigmatism after DALK. The location and extension of steep semi-meridians were determined using corneal topography. Office-based relaxing incision procedures were performed at the slit-lamp biomicroscope using a 27-gauge needle...
April 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28538335/bigaussian-wavefront-model-for-normal-and-keratoconic-eyes
#15
Jos J Rozema, Pablo Rodríguez, Rafael Navarro, Carina Koppen
PURPOSE: To report bigaussian multivariate wavefront models capable of stochastically generating an unlimited amount of plausible wavefront data for either normal or keratoconic eyes. METHODS: The models use centroid wavefront data measured previously with an iTrace in 330 healthy right eyes and 122 keratoconic right eyes. These centroids were fitted to an 11th-order Zernike series, followed by principal component analysis to reduce dimensionality and remove correlations...
June 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28495149/united-states-multicenter-clinical-trial-of-corneal-collagen-crosslinking-for-keratoconus-treatment
#16
Peter S Hersh, R Doyle Stulting, David Muller, Daniel S Durrie, Rajesh K Rajpal
PURPOSE: To evaluate the safety and efficacy of corneal collagen crosslinking (CXL) for the treatment of progressive keratoconus. DESIGN: Prospective, randomized, multicenter, controlled clinical trial. PARTICIPANTS: Patients with progressive keratoconus (n = 205). METHODS: The treatment group underwent standard CXL and the sham control group received riboflavin alone without removal of the epithelium. MAIN OUTCOME MEASURES: The primary efficacy criterion was the change over 1 year of topography-derived maximum keratometry value, comparing treatment with control group...
May 7, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28486724/noncontact-quantification-of-topography-of-anterior-corneal-surface-and-bowman-s-layer-with-high-speed-oct
#17
Himanshu Matalia, Mathew Francis, Tarun Gangil, Rachana S Chandapura, Mathew Kurian, Rohit Shetty, Everette Jacob Remington Nelson, Abhijit Sinha Roy
PURPOSE: To quantify keratometry and wavefront aberration of the anterior corneal surface and epithelium-Bowman's layer interface using anterior segment optical coherence tomography (OCT). METHODS: Twenty-five normal eyes and 25 eyes with keratoconus were retrospectively analyzed. The anterior corneal edge and epithelium-Bowman's layer interface were segmented from 12 distortion-corrected OCT B-scans. Axial tangential curvatures and wavefront aberration were calculated by ray tracing and 6th order Zernike analyses...
May 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28473428/to-show-the-efficacy-of-compressive-sutures-alone-in-the-management-of-acute-hydrops-in-a-keratoconus-patient
#18
Praveen Subudhi, Zahiruddin Khan, B Nageswar Rao Subudhi, Silla Sitaram
A 17-year-old boy presented with sudden loss of vision in the left eye (OS) for 3 days. He was diagnosed with acute hydrops following keratoconic progression in OS. The patient was initially started on topical medical therapy, including steroids and hypertonic eye drops; showing no signs of resolution. Hence, the patient was planned for full-thickness compressive corneal sutures. Four sutures were placed along the central oedematous area covering the area of ruptured Descemet's membrane. Signs of resolution were noticed by 1st week and there was complete resolution of oedema by 3rd post-op week...
May 4, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28470657/-morphologic-corneal-changes-after-crosslinking-for-keratoconus
#19
P L Müller, K U Löffler, M Kohlhaas, F G Holz, M C Herwig-Carl
Keratoconus is a relatively common (1 : 2000) bilateral disease leading to a change in biochemical and biomechanical corneal structure as well as thinning and ectasia. For more than 10 years, crosslinking has been a therapeutic option in cases of progression. Using riboflavin and UVA-radiation, the anterior corneal stroma (300 µm) gets stiffened by crosslinking of collagen fibers. When protocols and limitations are adhered, the procedure is described to be effective and of low-risk. This review gives an overview about physiologic and pathologic changes in keratoconic corneas before and after crosslinking...
May 3, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28458708/femtosecond-laser-arcuate-keratotomy-for-the-correction-of-postkeratoplasty-high-astigmatism-in-keratoconus
#20
Mohammad Naser Hashemian, Habib Ojaghi, Mehrdad Mohammadpour, Mahmoud Jabbarvand, Firouzeh Rahimi, Mohammad-Ali Abtahi, Mehdi Mazloumi, Seyed-Hossein Abtahi
BACKGROUND: Astigmatism is the leading complication in visual recovery after penetrating keratoplasty (PKP) and deep anterior lamellar keratoplasty (DALK); in this study, we evaluated the outcome of femtosecond laser arcuate keratotomy (FLAK) after DALK and PKP in Iranian keratoconic patients. MATERIALS AND METHODS: In this prospective interventional case series, refractive and keratometric predictability, efficacy, and complications of FLAK for postkeratoplasty astigmatism in keratoconus were evaluated; 23 eyes of 23 consecutive patients (mean age of 32...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
keyword
keyword
28017
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"