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https://www.readbyqxmd.com/read/29135710/adjustment-of-intrastromal-corneal-ring-segments-after-unsuccessful-implantation-in-keratoconic-eyes
#1
Tiago Monteiro, José Ferreira Mendes, Fernando Faria-Correia, Nuno Franqueira, David Madrid-Costa, José F Alfonso
PURPOSE: To evaluate visual, refractive, and corneal topography outcomes in eyes with keratoconus that have undergone exchange/adjustment surgery with a new intrastromal corneal ring segment (ICRS) combination after unsuccessful visual and/or refractive outcomes after primary ICRS surgery. METHODS: A retrospective nonrandomized case series was conducted including consecutive eyes of patients with keratoconus that underwent ICRS adjustment after an unsuccessful visual outcome...
November 13, 2017: Cornea
https://www.readbyqxmd.com/read/29124079/identifying-more-reliable-parameters-for-the-detection-of-change-during-the-follow-up-of-mild-to-moderate-keratoconus-patients
#2
Ivo Guber, Colm McAlinden, François Majo, Ciara Bergin
Background: Reaching a consensus on which parameters are most reliable at detecting progressive keratoconus patients with serial topography imaging is not evident. The aim of the study was to isolate the parameters best positioned to detect keratoconus progression using the Pentacam HR® measures based on the respective limits of repeatability and range of measurement. Method: Using the Pentacam HR®, a tolerance index was calculated on anterior segment parameters in healthy and keratoconic eyes...
2017: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/29120713/waveform-analysis-of-deformation-amplitude-and-deflection-amplitude-in%C3%A2-normal-suspect-and-keratoconic-eyes
#3
Mathew Francis, Natasha Pahuja, Rushad Shroff, Roshan Gowda, Himanshu Matalia, Rohit Shetty, Everette J Remington Nelson, Abhijit Sinha Roy
PURPOSE: To evaluate the performance of waveform-derived variables in distinguishing normal, suspect, and keratoconic eyes. SETTING: Narayana Nethralaya Eye Hospital, Bangalore, India. DESIGN: Retrospective case series. METHODS: Scheimpflug tomography (Pentacam) and dynamic Scheimpflug analysis (Corvis ST) of 253 normal (253 patients) eyes and 205 keratoconic eyes (205 patients) were evaluated. Among the 205 patients, 62 had keratoconus in 1 eye, while the unaffected eye was suspect...
October 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29120711/combined-transepithelial-phototherapeutic-keratectomy-and-conventional-photorefractive-keratectomy-followed-simultaneously-by-corneal-crosslinking-for-keratoconus-cretan-protocol-plus
#4
Michael A Grentzelos, George A Kounis, Vasilios F Diakonis, Charalambos S Siganos, Miltiadis K Tsilimbaris, Ioannis G Pallikaris, George D Kymionis
PURPOSE: To evaluate the visual, refractive, and topographic outcomes after combined transepithelial phototherapeutic keratectomy (PTK) and conventional photorefractive keratectomy (PRK) followed simultaneously by corneal crosslinking (CXL) for keratoconus. SETTING: Vardinoyiannion Eye Institute of Crete, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece. DESIGN: Prospective case series. METHODS: Patients with progressive keratoconus had simultaneous conventional PRK followed by CXL; the corneal epithelium was removed using transepithelial PTK (Cretan protocol plus)...
October 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29120710/femtosecond-laser-implantation-of%C3%A2-a%C3%A2-340-degree-intrastromal-corneal-ring%C3%A2-segment-in-keratoconus-short-term%C3%A2-outcomes
#5
Mohammad Mehdi Sadoughi, Bahram Einollahi, Amir Reza Veisi, Mohammad Zare, Mohammad Reza Sedaghat, Danial Roshandel, Neda Einollahi, Javad Rezaei
PURPOSE: To evaluate the short-term outcomes of femtosecond laser-assisted implantation of a 340-degree intracorneal ring (ICR) (Keraring) in patients with keratoconus. SETTING: Four centers in Iran. DESIGN: Prospective case series. METHODS: All cases had implantation of the 340-degree ICR after tunnel creation with a femtosecond laser. The uncorrected (UDVA) and corrected (CDVA) distance visual acuities, sphere, cylinder, manifest refraction spherical equivalent (MRSE), mean keratometry (K), steep K, and flat K were evaluated preoperatively and 1, 3, and 6 months postoperatively...
October 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29117418/keratoconus-screening-with-dynamic-biomechanical-in-vivo-scheimpflug-analyses-a-proof-of-concept-study
#6
Johannes Steinberg, Nazanin Eslami Amirabadi, Andreas Frings, Juliane Mehlan, Toam Katz, Stephan J Linke
PURPOSE: This proof-of-concept study was designed to analyze the ability of in vivo biomechanical corneal analyses with the corneal visualization Scheimpflug technology (CorvisST; Oculus Optikgeräte, Wetzlar, Germany) to differentiate between normal eyes and eyes with manifest keratoconus after strictly eliminating the potential confounding factors intraocular pressure (IOP) and central corneal thickness (CCT). METHODS: In this retrospective, cross-sectional study, after pairwise matching for CCT and IOP, 29 normal eyes and 29 keratoconic eyes (one eye from each patient) were selected as study population...
November 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29117417/repeatability-of-a-commercially-available-adaptive-optics-visual-simulator-and-aberrometer-in-normal-and-keratoconic-eyes
#7
Rohit Shetty, Shruti Kochar, Tushar Grover, Pooja Khamar, Pallak Kusumgar, Kanchan Sainani, Abhijit Sinha Roy
PURPOSE: To evaluate the repeatability of aberration measurement obtained by a Hartmann-Shack aberrometer combined with a visual adaptive optics simulator in normal and keratoconic eyes. METHODS: One hundred fifteen normal eyes and 92 eyes with grade I and II keratoconus, as per the Amsler-Krumeich classification, were included in the study. To evaluate the repeatability, three consecutive measurements of ocular aberrations were obtained by a single operator. Zernike analyses up to the 5th order for a pupil size of 4...
November 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29032110/use-of-donors-predisposed-by-corneal-collagen-cross-linking-in-penetrating-keratoplasty-for-treating-the-patients-with-keratoconus
#8
Ting Huang, Ruifen Ye, Chen Ouyang, Chao Hou, Yunwei Hu, Qianni Wu
PURPOSE: To investigate whether use of donors predisposed by corneal collagen cross-linking (CXL) reduced myopic refractive errors for keratoconic eyes after penetrating keratoplasty (PK). DESIGN: Randomized controlled trial. METHODS: One hundred sixteen eyes of 116 patients with keratoconus from Zhongshan Ophthalmic Center were enrolled. Using stratified block randomization, eligible eyes were assigned to CXL graft group (Group1) or conventional graft group (Group2)...
October 12, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28991335/customized-corneal-cross-linking-using-different-uva-beam-profiles
#9
Rohit Shetty, Natasha Pahuja, Thimmarayappa Roshan, Rashmi Deshmukh, Mathew Francis, Arkasubhra Ghosh, Abhijit Sinha Roy
PURPOSE: To evaluate the performance of different customized corneal cross-linking (CXL) methods. METHODS: This was a single-center interventional, prospective, longitudinal case series. Four different customized CXL methods were evaluated in keratoconic eyes: (1) uniform (uniform intensity ultraviolet-A [UVA] beam [9 mW/cm(2)] for 10 minutes) (n = 12 eyes); (2) sector axial map (sector-based UVA irradiation) (n = 12 eyes); (3) ring axial map (concentric rings of UVA beam intensity centered at the steepest curvature of the anterior axial map) (n = 12 eyes); and ring tangential map (same as the ring axial map but centered at the steepest curvature of the anterior tangential map) (n = 14 eyes)...
October 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28991055/keratoconus-progression-in-patients-with-allergy-and-elevated-surface-matrix-metalloproteinase-9-point-of-care-test
#10
Cosimo Mazzotta, Claudio Traversi, Pierfrancesco Mellace, Simone A Bagaglia, Silvio Zuccarini, Rita Mencucci, Soosan Jacob
PURPOSE: To assess keratoconus (KC) progression in patients with allergies who also tested positive to surface matrix metalloproteinase 9 (MMP-9) point-of-care test. METHODS: Prospective comparative study including 100 stage I-II keratoconic patients, mean age 16.7±4.6 years. All patients underwent an anamnestic questionnaire for concomitant allergic diseases and were screened with the MMP-9 point-of-care test. Patients were divided into two groups: patients KC with allergies (KC AL) and patients KC without allergies (KC NAL)...
October 4, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28968292/aberrant-patterns-of-key-epithelial-basement-membrane-components-in-keratoconus
#11
Carol Ann Greene, Charisse Kuo, Trevor Sherwin
PURPOSE: In the cornea, the epithelial basement membrane (BM) plays an important role in maintaining corneal integrity and homeostasis. Aberrations in this vital structure are associated with several corneal pathologies including keratoconus. The aim of this study was to investigate the expression of key structural components of the epithelial BM in keratoconic corneas and to identify and describe any aberrant patterns. METHODS: Immunohistochemical labeling of key BM components including fibronectin, laminin, and type IV and VII collagen was performed in healthy and keratoconic corneas...
December 2017: Cornea
https://www.readbyqxmd.com/read/28961565/cataract-surgery-in-eyes-with-keratoconus-a-review-of-the-current-literature
#12
Majid Moshirfar, Brian D Walker, Orry C Birdsong
PURPOSE OF REVIEW: There are an increasing number of keratoconic eyes, requiring cataract surgery. We review the preoperative planning, intraoperative options, and postoperative management that aid in successful outcomes. RECENT FINDINGS: Management of keratoconic eyes requiring cataract surgery requires a multifaceted approach. Preoperatively, corneal crosslinking and intrastromal corneal ring segments can be considered in order to provide stable keratometry values for intraocular lens (IOL) calculations...
September 28, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28948045/long-term-follow-up-of-intrastromal-corneal-ring-segments-in-paracentral-keratoconus-with-coincident-corneal-keratometric-comatic-and-refractive-axes-stability-of-the-procedure
#13
Luis Fernández-Vega Cueto, Carlos Lisa, David Madrid-Costa, Jesús Merayo-Lloves, José F Alfonso
PURPOSE: To assess the long-term outcomes of implanting intrastromal corneal ring segments (ICRS) in paracentral keratoconic eyes. METHODS: 58 eyes with paracentral keratoconus with coincident refractive, keratometric, and comatic axes were evaluated. Uncorrected (UDVA) and corrected (CDVA) distance visual acuity and refractive errors were recorded before and at all follow-up visits. The postoperative follow-up was 5 years. Patients were divided into two groups: group I (30 years old or younger) and group II (more than 30 years old)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28945648/clinical-study-of-mitomycin-c-in-reducing-haze-formation-after-ultraviolet-a-riboflavin-crosslinking-for-keratoconus
#14
Linlin Xu, Xiangchen Tao, Zhiwei Li, Yanyun Xu, Wei Zhu, Huijuan Xu, Wei Pu, Yi Xie, Guoying Mu
OBJECTIVES: To evaluate the safety and efficacy of mitomycin C (MMC) in haze formation after ultraviolet A/riboflavin corneal crosslinking (CXL) for progressive keratoconus. METHODS: A total of 60 keratoconic eyes of 48 patients were enrolled in this prospective comparative study after obtaining informed consent. In the CXL group, standard corneal CXL was performed, whereas in the CXL+MMC group, 0.02% MMC was used for 30 s soon after CXL. Comprehensive ophthalmologic examinations were performed on all patients before surgery and at 1, 3, 6, and 12 months after surgery...
September 21, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28932341/pathophysiology-of-keratoconus-what-do-we-know-today
#15
Uri Soiberman, James W Foster, Albert S Jun, Shukti Chakravarti
Keratoconus is a common corneal ectasia that leads to progressive visual impairment. Numerous studies have shown abnormal protein expression patterns in keratoconic corneas. However, the specific mechanisms causing this disease remain ambiguous. This review aims to provide an update on morphological studies of the keratoconic cornea, relate these early studies with current findings from proteomic, biochemical and cell culture studies and to postulate possible pathogenic pathways.
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28932335/cataract-surgery-in-patients-with-keratoconus-pearls-and-pitfalls
#16
F Aiello, Q J Nasser, C Nucci, R I Angunawela, Z Gatzioufas, V Maurino
BACKGROUND: Keratoconus (KC) is a common ectatic disorder resulting in progressive corneal thinning and irregular astigmatism. It has been observed that patients affected by KC are more likely to develop lens opacities earlier compared to non-keratoconic patients. OBJECTIVE: Intraocular lens (IOL) selection and refractive outcome prediction are among a number of factors that can make cataract surgery in keratoconic patients challenging. Accurate biometry is often difficult to obtain due to unreliable K measurements and lack of dedicated biometric formulae...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28926888/-accelerated-transepithelial-corneal-collagen-cross-linking-for-progressive-keratoconus-with-a-thin-cornea-one-year-results
#17
Z R Lin, H P Wu, S R Luo, Z S Liu, N Dong, X M Shang, Z W Xie, L Yan, X Fang
Objective: To evaluate the clinical results of keratoconic eyes with a thin cornea treated with accelerated transepithelial corneal collagen cross-linking (A-TE-CXL) within 1 year. Methods: Nineteen eyes of 19 patients with progressive keratoconus with a minimum corneal thickness from 380 μm to 420 μm (including the epithelium) were included in this prospective, nonrandomized clinical study and treated with A-TE-CXL. Scoring of pain and foreign body sensation, slit lamp examination, uncorrected visual acuity, best corrected distance visual acuity, corneal topography, anterior segment optical coherence tomography, in vivo corneal confocal microscopy and endothelial cell count were assessed before surgery and at 1, 3, 6 and 12 months postoperatively...
September 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28913509/effects-of-single-segment-intacs-implantation-on-visual-acuity-and-corneal-topographic-indices-of-keratoconus
#18
Kazem Amanzadeh, Roghiyeh Elham, Ebrahim Jafarzadepur
PURPOSE: To assess the changes in visual acuity and topographic indices after implantation of single-segment Intacs. METHODS: Forty-two keratoconic eyes received Femtosecond-assisted single-segment Intacs. Uncorrected distance visual acuity (UDVA) and best spectacle corrected visual acuity (BSCVA), refractive error, keratometry (K1, K2, Km, and KMax.), and seven Pentacam measured topographical indices; index of surface variance (ISV), index of vertical asymmetry (IVA), keratoconus index (KI), central keratoconus index (CKI), index of height asymmetry (IHA), index of height decentration (IHD), and minimum radius of curvature (R Min) were assessed 4 months after surgery...
September 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28913507/keratoconus-diagnosis-using-corvis-st-measured-biomechanical-parameters
#19
Roghiyeh Elham, Ebrahim Jafarzadehpur, Hassan Hashemi, Kazem Amanzadeh, Fereshteh Shokrollahzadeh, Abbasali Yekta, Mehdi Khabazkhoob
PURPOSE: To assess the diagnostic power of the Corneal Visualization Scheimpflug Technology (Corvis ST) provided corneal biomechanical parameters in keratoconic corneas. METHODS: The following biomechanical parameters of 48 keratoconic eyes were compared with the corresponding ones in 50 normal eyes: time of the first applanation and time from start to the second applanation [applanation-1 time (A1T) and applanation-2 time (A2T)], time of the highest corneal displacement [highest concavity time (HCT)], magnitude of the displacement [highest concavity deformation amplitude (HCDA)], the length of the flattened segment in the applanations [first applanation length (A1L) and second applanation length (A2L)], velocity of corneal movement during applanations [applanation-1 velocity (A1V) and applanation-2 velocity (A2V)], distance between bending points of the cornea at the highest concavity [highest concavity peak distance (HCPD)], central concave curvature at the highest concavity [highest concavity radius (HCR)]...
September 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28905822/higher-order-aberration-4-years-after-corneal-collagen-cross-linking
#20
Mohammad Naderan, Ali Jahanrad
PURPOSE: Corneal collagen cross-linking (CXL) is a treatment strategy used in keratoconic eyes. Evaluation of long-term changes of higher-order aberrations (HOAs) after CXL is useful in understanding the efficacy of this procedure in improving optical, refractive, and visual acuity. This study aims to investigate the long-term effect of CXL on ocular HOA in patients with progressive keratoconus (KC). METHODS: Using an OPD-Scan II aberrometer, ocular HOAs measurements of 56 eyes of 56 patients that underwent CXL was evaluated at the baseline, 1, 2, and 4 years after the procedure...
September 2017: Indian Journal of Ophthalmology
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