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https://www.readbyqxmd.com/read/29782996/reducing-waste-in-evaluation-studies-on-fall-risk-assessment-tools-for-older-people
#1
Gabriele Meyer, Ralph Möhler, Sascha Köpke
OBJECTIVE: To critically appraise the recognition of methodological challenges in evaluation studies on assessment tools and nurses' clinical judgement on fall risk in older people and suggest how to reduce respective research waste. STUDY DESIGN: Opinion paper and narrative review covering systematic reviews on studies assessing diagnostic accuracy and impact of assessment tools and/or nurses' clinical judgement. RESULTS: Eighteen reviews published in the last 15 years were analysed...
May 18, 2018: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29770054/new-vaccine-administration-practice-recommendations-from-the-canadian-immunization-guide
#2
C Jensen, D Moore, C Mah, O Baclic, S Marchant-Short
Background: The Canadian Immunization Guide (CIG) is published online by the Public Health Agency of Canada and summarizes guidance on vaccines for human use into a single resource. Chapters are reviewed and updated on a regular basis. Vaccine administration is a critical part of any immunization program. Recently, the CIG chapter on vaccine administration practices was updated. Objective: To provide highlights of recent changes to the Vaccine Administration Practices chapter of the CIG...
November 2, 2017: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29769414/clinical-utility-of-arterial-spin-labeling-for-preoperative-grading-of-glioma-a-diagnostic-meta-analysis
#3
Linchen Li, Xinjun Wang, Min Zhang, Yan Zhang
There were obvious differences in biological behavior and prognosis between low-grade glioma and high-grade glioma, it is of great importance for clinicians to make a right judgement for preoperative grading. We conducted a comprehensive meta-analysis to evaluate the clinical utility of arterial spin labeling for preoperative grading. We searched the PubMed, Embase, China National Knowledge Infrastructure, and Weipu electronic databases for articles published through November 10, 2017 and used "arterial spin-labeling" OR "ASL perfusion, grading" OR "differentiation, glioma" OR "glial tumor, diagnostic test" as the search terms...
May 16, 2018: Bioscience Reports
https://www.readbyqxmd.com/read/29767459/long-term-effects-of-patiromer-for-hyperkalaemia-treatment-in-patients-with-mild-heart-failure-and-diabetic-nephropathy-on-angiotensin-converting-enzymes-angiotensin-receptor-blockers-results-from-amethyst-dn
#4
Bertram Pitt, George L Bakris, Matthew R Weir, Mason W Freeman, Mitja Lainscak, Martha R Mayo, Dahlia Garza, Rezi Zawadzki, Lance Berman, David A Bushinsky
AIMS: Chronic kidney disease (CKD) in heart failure (HF) increases the risk of hyperkalaemia (HK), limiting angiotensin-converting enzyme inhibitor (ACE-I) or angiotensin receptor blocker (ARB) use. Patiromer is a sodium-free, non-absorbed potassium binder approved for HK treatment. We retrospectively evaluated patiromer's long-term safety and efficacy in HF patients from AMETHYST-DN. METHODS AND RESULTS: Patients with Type 2 diabetes, CKD, and HK [baseline serum potassium >5...
May 16, 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/29754596/sharing-solutions-for-a-reasoned-and-evidence-based-response-chemsex-party-and-play-among-gay-and-bisexual-men
#5
Adam Bourne, Jason Ong, Mark Pakianathan
This Special Issue of Sexual Health examines research and healthcare practice relating to sexualised drug use among gay, bisexual and other men who have sex with men (GBMSM), colloquially known as 'chemsex' or 'party and play' (PnP). It draws together evidence relating to the epidemiology, sociology and psychology of chemsex, as well as the policy, community and clinical interventions that are required to ensure men have access to high-quality health care that meets their needs and reduces harm. Findings and discussions within the Issue emphasise the need to sensitively, non-judgementally and meaningfully engage with gay men about their engagement in chemsex in order to help improve their sexual health and wider wellbeing...
April 2018: Sexual Health
https://www.readbyqxmd.com/read/29754583/validity-evidence-for-the-hamburg-multiple-mini-interview
#6
Mirjana Knorr, Anja Schwibbe, Maren Ehrhardt, Janina Lackamp, Stefan Zimmermann, Wolfgang Hampe
BACKGROUND: Multiple mini-interviews (MMI) become increasingly popular for the selection of medical students. In this work, we examine the validity evidence for the Hamburg MMI. METHODS: We conducted three follow-up studies for the 2014 cohort of applicants to medical school over the course of two years. We calculated Spearman's rank correlation (ρ) between MMI results and (1) emotional intelligence measured by the Trait Emotional Intelligence Questionnaire (TEIQue-SF) and the Situational Test of Emotion Management (STEM), (2) supervisors' and practice team members' evaluations of psychosocial competencies and suitability for the medical profession after a one-week 1:1 teaching in a general practice (GP) and (3) objective structured clinical examination (OSCE) scores...
May 14, 2018: BMC Medical Education
https://www.readbyqxmd.com/read/29752213/-when-no-one-s-looking-the-application-of-lung-recruitment-and-normal-saline-instillation-with-paediatric-endotracheal-suction-an-exploratory-study-of-nursing-practice
#7
Jessica A Schults, Marie Cooke, Debbie Long, Marion L Mitchell
BACKGROUND: The complex nature of the Paediatric Intensive Care Unit (PICU) patient requires the bedside nurse to make rapid, complex decisions regarding endotracheal suction (ETS) interventions. It is not understood what influences nurses' decision making in the context of ETS, however, the actions of the clinician have a direct impact on the efficacy of the ETS event and patient outcomes. OBJECTIVES: To explore and describe the use of normal saline instillation and lung recruitment with paediatric ETS in a cohort of Australian nurses, and to identify factors that influence normal saline use with ETS...
May 8, 2018: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/29750096/three-dimensional-reliability-analyses-of-currently-used-methods-for-assessment-of-sagittal-jaw-discrepancy
#8
Bushra-Sufyan Almaqrami, Maged-Sultan Alhammadi, BaoChang Cao
Background: The objective of this study was to analyse three dimensionally the reliability and correlation of angular and linear measurements in assessment of anteroposterior skeletal discrepancy. Material and Methods: In this retrospective cross sectional study, a sample of 213 subjects were three-dimensionally analysed from cone-beam computed tomography scans. The sample was divided according to three dimensional measurement of anteroposterior relation (ANB angle) into three groups (skeletal Class I, Class II and Class III)...
April 2018: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29745853/a-new-method-to-measure-the-semantic-similarity-from-query-phenotypic-abnormalities-to-diseases-based-on-the-human-phenotype-ontology
#9
Xiaofeng Gong, Jianping Jiang, Zhongqu Duan, Hui Lu
BACKGROUND: Although rapid developed sequencing technologies make it possible for genotype data to be used in clinical diagnosis, it is still challenging for clinicians to understand the results of sequencing and make correct judgement based on them. Before this, diagnosis based on clinical features held a leading position. With the establishment of the Human Phenotype Ontology (HPO) and the enrichment of phenotype-disease annotations, there throws much more attention to the improvement of phenotype-based diagnosis...
May 8, 2018: BMC Bioinformatics
https://www.readbyqxmd.com/read/29739387/variability-and-dimensionality-of-students-and-supervisors-mini-cex-scores-in-undergraduate-medical-clerkships-a-multilevel-factor-analysis
#10
Christoph Berendonk, Anja Rogausch, Armin Gemperli, Wolfgang Himmel
BACKGROUND: The mini clinical evaluation exercise (mini-CEX)-a tool used to assess student-patient encounters-is increasingly being applied as a learning device to foster clinical competencies. Although the importance of eliciting self-assessment for learning is widely acknowledged, little is known about the validity of self-assessed mini-CEX scores. The aims of this study were (1) to explore the variability of medical students' self-assessed mini-CEX scores, and to compare them with the scores obtained from their clinical supervisors, and (2) to ascertain whether learners' self-assessed mini-CEX scores represent a global dimension of clinical competence or discrete clinical skills...
May 8, 2018: BMC Medical Education
https://www.readbyqxmd.com/read/29736594/a-decision-support-tool-facilitating-medicine-design-for-optimal-acceptability-in-the-older-population
#11
Thibault Vallet, Emilie Belissa, Sandra Laribe-Caget, Alain Chevallier, François-Xavier Chedhomme, Patrick Leglise, Matthieu Piccoli, Hugues Michelon, Vanessa Bloch, Sylvie Meaume, Anne-Sophie Grancher, Nathalie Bachalat, Imad Boulaich, Fattima Abdallah, Maite Rabus, Jean-Paul Rwabihama, Annie-Claude Ribemont, Celia Lachuer, Ines Perquy, Laurent Lechowski, Anne Delahaye, Mathieu Depoisson, Yann Orven, Caroline Guinot, Stephane Gibaud, Corinne Michel, Abdel Mahiou, Sid-Ahmed Belbachir, Jean-Hugues Trouvin, Amelie Dufaÿ-Wojcicki, Vincent Boudy, Fabrice Ruiz
PURPOSE: Medicine acceptability, which is of the utmost importance for vulnerable patients' adherence, is driven by both user and product characteristics. Herein, a novel multivariate approach integrating the many aspects of acceptability is used to discriminate positively and negatively accepted medicines in the older population. METHODS: An observational study was carried out in eight hospitals and eight nursing homes to collect a large set of real-life data on medicines uses in older patients (≥65 years)...
May 7, 2018: Pharmaceutical Research
https://www.readbyqxmd.com/read/29732145/rapid-acting-fentanyl-formulations-in-breakthrough-pain-in-cancer-drug-selection-by-means-of-the-system-of-objectified-judgement-analysis
#12
Robert Janknegt, Marieke van den Beuken, Sjouke Schiere, Michael Überall, Roger Knaggs, Jaquie Hanley, Morten Thronaes
Drug selection of rapid acting fentanyl formulations in the treatment of breakthrough pain in patients with cancer is performed by the System of Objectified Judgement Analysis method. All seven available formulations were included in the analysis. The following selection criteria were used: number of available strengths, variability in the rate of absorption, interactions, clinical efficacy, side effects, ease of administration and documentation. No direct double-blind comparative studies between two or more formulations were identified and the clinical documentation of all formulations is limited...
May 2018: European Journal of Hospital Pharmacy. Science and Practice
https://www.readbyqxmd.com/read/29731263/wasp-write-a-scientific-paper-recruitment-for-research
#13
Pierre Mallia
The recruitment of patients must occur in accordance with approved standards. Speaking to a patient during a routine clinical consultation and offering to participate in a research, even if consented to, can only be an introduction to the recruitment process. The potential participant must then be referred to a competent person who explains the reasons for the research, why the patient is a good candidate, what the requirements from the participant will be, such as any additional visits and blood samples to be taken, how long the research will last, any compensation and what type of research is to be undertaken, such as a double blind-controlled trial and what it means...
May 3, 2018: Early Human Development
https://www.readbyqxmd.com/read/29724154/in-silico-computed-modelling-of-doses-and-dosing-regimens-associated-with-morphine-levels-above-international-legal-driving-limits
#14
Jason W Boland, Miriam Johnson, Diana Ferreira, David J Berry
BACKGROUND: Morphine can cause central nervous system side effects which impair driving skills. The legal blood morphine concentration limit for driving is 20 µg/L in France/Poland/Netherlands and 80 µg/L in England/Wales. There is no guidance as to the morphine dose leading to this concentration. AIM: The in silico (computed) relationship of oral morphine dose and plasma concentration was modelled to provide dose estimates for a morphine plasma concentration above 20 and 80 µg/L in different patient groups...
May 1, 2018: Palliative Medicine
https://www.readbyqxmd.com/read/29724130/elucidating-inconsistencies-in-dysphagia-diagnostics-redefining-normal
#15
Emily K Plowman, Ianessa A Humbert
Speech-language pathologists (SLPs) are the primary healthcare providers responsible for the evaluation and treatment of dysphagia. Fundamental to this role is the ability to make accurate clinical judgements to distinguish between normal versus disordered swallowing for subsequent treatment planning. In this review, we highlight recent data collected from practising clinicians in the USA that reveal low levels of agreement across clinicians and poor to moderate levels of accuracy for making binary diagnostic ratings (normal vs...
May 3, 2018: International Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/29717691/probability-of-major-depression-diagnostic-classification-using-semi-structured-versus-fully-structured-diagnostic-interviews
#16
Brooke Levis, Andrea Benedetti, Kira E Riehm, Nazanin Saadat, Alexander W Levis, Marleine Azar, Danielle B Rice, Matthew J Chiovitti, Tatiana A Sanchez, Pim Cuijpers, Simon Gilbody, John P A Ioannidis, Lorie A Kloda, Dean McMillan, Scott B Patten, Ian Shrier, Russell J Steele, Roy C Ziegelstein, Dickens H Akena, Bruce Arroll, Liat Ayalon, Hamid R Baradaran, Murray Baron, Anna Beraldi, Charles H Bombardier, Peter Butterworth, Gregory Carter, Marcos H Chagas, Juliana C N Chan, Rushina Cholera, Neerja Chowdhary, Kerrie Clover, Yeates Conwell, Janneke M de Man-van Ginkel, Jaime Delgadillo, Jesse R Fann, Felix H Fischer, Benjamin Fischler, Daniel Fung, Bizu Gelaye, Felicity Goodyear-Smith, Catherine G Greeno, Brian J Hall, John Hambridge, Patricia A Harrison, Ulrich Hegerl, Leanne Hides, Stevan E Hobfoll, Marie Hudson, Thomas Hyphantis, Masatoshi Inagaki, Khalida Ismail, Nathalie Jetté, Mohammad E Khamseh, Kim M Kiely, Femke Lamers, Shen-Ing Liu, Manote Lotrakul, Sonia R Loureiro, Bernd Löwe, Laura Marsh, Anthony McGuire, Sherina Mohd Sidik, Tiago N Munhoz, Kumiko Muramatsu, Flávia L Osório, Vikram Patel, Brian W Pence, Philippe Persoons, Angelo Picardi, Alasdair G Rooney, Iná S Santos, Juwita Shaaban, Abbey Sidebottom, Adam Simning, Lesley Stafford, Sharon Sung, Pei Lin Lynnette Tan, Alyna Turner, Christina M van der Feltz-Cornelis, Henk C van Weert, Paul A Vöhringer, Jennifer White, Mary A Whooley, Kirsty Winkley, Mitsuhiko Yamada, Yuying Zhang, Brett D Thombs
BACKGROUND: Different diagnostic interviews are used as reference standards for major depression classification in research. Semi-structured interviews involve clinical judgement, whereas fully structured interviews are completely scripted. The Mini International Neuropsychiatric Interview (MINI), a brief fully structured interview, is also sometimes used. It is not known whether interview method is associated with probability of major depression classification.AimsTo evaluate the association between interview method and odds of major depression classification, controlling for depressive symptom scores and participant characteristics...
May 2, 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29713908/when-to-trust-our-learners-clinical-teachers-perceptions-of-decision-variables-in-the-entrustment-process
#17
Chantal C M A Duijn, Lisanne S Welink, Harold G J Bok, Olle T J Ten Cate
INTRODUCTION: Clinical training programs increasingly use entrustable professional activities (EPAs) as focus of assessment. However, questions remain about which information should ground decisions to trust learners. This qualitative study aimed to identify decision variables in the workplace that clinical teachers find relevant in the elaboration of the entrustment decision processes. The findings can substantiate entrustment decision-making in the clinical workplace. METHODS: Focus groups were conducted with medical and veterinary clinical teachers, using the structured consensus method of the Nominal Group Technique to generate decision variables...
April 30, 2018: Perspectives on Medical Education
https://www.readbyqxmd.com/read/29693788/-what-the-hell-is-water-how-to-use-deliberate-clinical-inertia-in-common-emergency-department-situations
#18
Diana Egerton-Warburton, Louise Cullen, Gerben Keijzers, Daniel M Fatovich
Appropriate deliberate clinical inertia refers to the art of doing nothing as a positive clinical response. It includes shared decision-making to improve patient care with the use of clinical judgement. We discuss common clinical scenarios where the use of deliberate clinical inertia can occur. The insertion of peripheral intravenous cannulae, investigating patients with suspected renal colic and the investigation of low risk chest pain are all opportunities for the thoughtful clinician to 'stand there' and use effective patient communication to avoid low value tests and procedures...
April 25, 2018: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29693206/3d-printed-model-improves-clinical-assessment-of-surgeons-on-anatomy
#19
Bin Zheng, Xiaolin Wang, Yixiong Zheng, Jiexiong Feng
Performing surgical procedures often requires a surgeon to develop a skill to create 3-dimensional (3D) mental model on patient's anatomy. Question remains whether the touching on the 3D printed model can facilitate learning of patient anatomy than viewing the rendered virtual on-screen model. The printed and the virtual 3D model were developed from CT films taken from a 4-year-old girl, who had dysplasia of the hip in the left hip. Eleven subjects were called to report measures on six key anatomical features on the hips...
April 24, 2018: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/29691965/clinical-judgement-multidisciplinary-perspectives
#20
Benjamin Chin-Yee, Jonathan Fuller
No abstract text is available yet for this article.
April 25, 2018: Journal of Evaluation in Clinical Practice
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