keyword
MENU ▼
Read by QxMD icon Read
search

Botox and incontinence

keyword
https://www.readbyqxmd.com/read/29482936/two-year-outcomes-of-sacral-neuromodulation-versus-onabotulinumtoxina-for-refractory-urgency-urinary-incontinence-a-randomized-trial
#1
Cindy L Amundsen, Yuko M Komesu, Christopher Chermansky, W Thomas Gregory, Deborah L Myers, Emily F Honeycutt, Sandip P Vasavada, John N Nguyen, Tracey S Wilson, Heidi S Harvie, Dennis Wallace
BACKGROUND: Urgency urinary incontinence (UUI) is a chronic condition for which sacral neuromodulation (SNM) (InterStim/Medtronic) and onabotulinumtoxinA (BTX) (BotoxA/Allergan) are utilized. These therapies have not been compared over extended time. OBJECTIVE: To compare UUI episodes (UUIE) over 24 mo following SNM or BTX. DESIGN, SETTING, AND PARTICIPANTS: Multicenter, open-label, randomized, extension trial (February 2012-July 2016) at nine US medical centers involving 386 women with ≥6 UUIE over 3 d inadequately managed by medications...
February 23, 2018: European Urology
https://www.readbyqxmd.com/read/29329897/-botulinium-toxin-and-idiopathic-overactive-bladder-multicentric-contempory-management-in-bourgogne
#2
A Schneider, B Tourlonias, L Cormier, E Mourey, N Koutlidis, E Delorme, J Pasquale, I Kermarec, A-D Foahom-Kamwa, V Bonniaud
INTRODUCTION: Since 2014, OnabotulinumtoxinA Botox® (Allergan, Inc., Irvine, USA) represents a new therapeutic option for second-line treatment of idiopathic overactive bladder. The purpose of the current study was to evaluate practices of surgeons using onabotulinium toxin (BoNTA) in this indication. MATERIAL AND METHODS: All urogynecology centers of the country were asked in order to list all patients who were treated since marketing autorisation. Patient symptoms, previous treatments, paraclinic evaluations, data of surgery and the characteristics of the follow up were collected and analyzed...
March 2018: Progrès en Urologie
https://www.readbyqxmd.com/read/29275144/case-presentation-botox-versus-nerve-stimulation
#3
R J A van Moorselaar, Jakko A Nieuwenhuijzen
A woman experiencing very strong urgency and associated frequency of micturition, but no incontinence, and deep dyspareunia was eventually diagnosed with idiopathic detrusor overactivity with symptoms of overactive bladder symptom complex and potentially bladder pain syndrome. A trial of neuromodulation was unsuccessful, but injections of onabotulinum toxin A have had a good effect.
December 20, 2017: European Urology Focus
https://www.readbyqxmd.com/read/28817919/re-cost-effectiveness-analysis-of-anticholinergics-versus-botox-for-urgency-urinary-incontinence-results-from-the-anticholinergic-versus-botox-comparison-randomized-trial
#4
https://www.readbyqxmd.com/read/28791229/impact-of-bladder-dysfunction-in-the-management-of-post-radical-prostatectomy-stress-urinary-incontinence-a-review
#5
REVIEW
Derek B Hennessey, Nathan Hoag, Johan Gani
Bladder dysfunction is a relatively common urodynamic finding post radical prostatectomy (RP). It can be the sole cause of post prostatectomy incontinence (PPI) or may be found in association with stress urinary incontinence (SUI). The aim of this review is to provide a comprehensive review of the diagnosis and different treatments of post RP bladder dysfunction. A comprehensive literature review using medical search engines was performed. The search included a combination of the following terms, PPI, detrusor overactivity (DO), detrusor underactivity (DU), impaired compliance, anticholinergic, onabotulinumtoxinA (Botox® ) and sacral neuromodulation (SNM)...
July 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28714784/the-management-of-paediatric-neurogenic-bladder-an-approach-in-a-resource-poor-setting
#6
Patrick Opoku Manu Maison, John Lazarus
BACKGROUND: If untreated, paediatric neurogenic bladder can cause renal failure and urinary incontinence. It is usually caused by neural tube defects such as myelomeningocele. Children with a neurogenic bladder should be monitored from birth and management should aim to preserve renal function and achieve social continence. This article outlines the management options appropriate for these children in resource-poor settings. ASSESSMENT: In most low- and middle-income countries, a general lack of awareness of the neurological effects on the urinary tract results in late presentation, usually with urological complications even when spina bifida is diagnosed early...
November 2017: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/28431196/switch-to-abobotulinum-toxin-a-may-be-useful-in-the-treatment-of-neurogenic-detrusor-overactivity-when-intradetrusor-injections-of-onabotulinum-toxin-a-failed
#7
Florie Bottet, Benoit Peyronnet, Romain Boissier, Bénédicte Reiss, Jean G Previnaire, Andrea Manunta, Jacques Kerdraon, Alain Ruffion, Loïc Lenormand, Brigitte Perrouin Verbe, Sarah Gaillet, Xavier Gamé, Gilles Karsenty
AIMS: To assess the outcomes of switching to a different brand of botulinum toxin A (BTA, from Botox® to Dysport®) in case of failure of intradetrusor injections (IDI) of Botox® in the treatment of neurogenic detrusor overactivity (NDO). METHODS: The charts of all patients who underwent a switch to IDI of Dysport® after failure of an IDI of Botox® at six departments of neurourology were retrospectively reviewed. The main outcomes of interest were the bladder diary data and four urodynamic parameters: maximum cystometric capacity (MCC), maximum detrusor pressure (PDET max), and volume at first uninhibited detrusor contraction (UDC)...
January 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28363809/vaginismus-treatment-clinical-trials-follow-up-241-patients
#8
Peter T Pacik, Simon Geletta
INTRODUCTION: Vaginismus is mostly unknown among clinicians and women. Vaginismus causes women to have fear, anxiety, and pain with penetration attempts. AIM: To present a large cohort of patients based on prior published studies approved by an institutional review board and the Food and Drug Administration using a comprehensive multimodal vaginismus treatment program to treat the physical and psychologic manifestations of women with vaginismus and to record successes, failures, and untoward effects of this treatment approach...
June 2017: Sexual Medicine
https://www.readbyqxmd.com/read/28261683/botox-combined-with-myofascial-release-physical-therapy-as-a-treatment-for-myofascial-pelvic-pain
#9
Gabriela E Halder, Lauren Scott, Allison Wyman, Nelsi Mora, Branko Miladinovic, Renee Bassaly, Lennox Hoyte
PURPOSE: To report the effects of combined onabotulinumtoxinA (Botox) injections and myofascial release physical therapy on myofascial pelvic pain (MFPP) by comparing pre- and posttreatment average pelvic pain scores, trigger points, and patient self-reported pelvic pain. Secondary outcomes were to examine posttreatment complications and determine demographic differences between patients with/without an improvement in pain. MATERIALS AND METHODS: This was an Institutional Review Board approved retrospective case series on women over 18 years with MFPP who received Botox and physical therapy between July 2006 and November 2014...
March 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/27701762/impact-of-intravesical-onabotulinumtoxina-on-sexual-function-in-women-with-oab
#10
Pawel Miotla, Rufus Cartwright, Katarzyna Skorupska, Michal Bogusiewicz, Ewa Markut-Miotla, Konrad Futyma, Tomasz Rechberger
AIMS: Urgency urinary incontinence (UUI), and the symptoms of overactive bladder (OAB) have a negative impact on female sexual function. The aim of this study was to investigate the effect of intravesical onabotulinumtoxinA (Botox) injection on sexual function in women with OAB, using the multi domain Female Sexual Function Index (FSFI) questionnaire. METHODS: Sixty-eight sexually active women with idiopathic OAB with at least one episode of UUI and ≥8 micturitions per 24 h were recruited...
August 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27676712/efficacy-and-safety-of-a-first-intradetrusorial-injection-of-botulinum-toxin-a-for-the-treatment-of-refractory-overactive-bladder-in-54-elderly-patients
#11
Laura Weglinski, Rebecca Haddad, Benoit Peyronnet, Xavier Game, Calin Ciofu, Gerard Amarenco
OBJECTIVE: Intradetrusorial injection of botulinum toxin A (IDBT) is a validated treatment for neurogenic and non-neurogenic refractory overactive bladder. In the elderly, muscarinic antagonists have many side effects, in particular in cognition. An alternative treatment is, for that reason, interesting in this frail population with multiple medication use. The question of efficacy is remaining. Indeed, bladder dysfunction is most of the time a multifactorial issue in the elderly. The objective of this study was to evaluate prospectively the efficacy and safety of IDBT in this population...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27564385/cost-effectiveness-analysis-of-anticholinergics-versus-botox-for-urgency-urinary-incontinence-results-from-the-anticholinergic-versus-botox-comparison-randomized-trial
#12
RANDOMIZED CONTROLLED TRIAL
Anthony G Visco, Halina Zyczynski, Linda Brubaker, Ingrid Nygaard, Xiao Xu, Emily S Lukacz, Marie Fidela Paraiso, Jerod Greer, David D Rahn, Susan F Meikle, Amanda A Honeycutt
OBJECTIVES: This study aimed to compare the cost-effectiveness of Botox and anticholinergic (AC) medications for the management of urgency urinary incontinence (UUI). METHODS: Cost and effectiveness data were analyzed from participants in the Anticholinergic versus Botox Comparison randomized trial of daily AC medication versus 100 U of intradetrusor Botox injection. Societal costs included the following: treatment costs, patient costs, and medical and nonmedical utilization during the 6-month trial...
September 2016: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/27539490/botulinum-toxin-injection-for-treatment-of-chronic-anal-fissure-is-there-any-dose-dependent-efficiency-a-meta-analysis
#13
REVIEW
Adam Bobkiewicz, Wojciech Francuzik, Lukasz Krokowicz, Adam Studniarek, Witold Ledwosiński, Jacek Paszkowski, Michal Drews, Tomasz Banasiewicz
BACKGROUND: Chronic anal fissure (CAF) is a linear split of the anoderm. The minimally invasive management of CAF such as botulinum toxin (BT) injection is recommended. However, the exact efficient dose of BT, number of injections per session and the injection sites are still debatable. The aim of this analysis was to assess the dose-dependent efficiency of botulinum toxin injection for CAF. METHODS: PubMed and Web of Science databases were searched for terms: "anal fissure" AND "botulinum toxin...
December 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27152397/botulinum-toxin-type-a-botox-and-idiopathic-overactive-bladder-for-some-severely-affected-patients
#14
(no author information available yet)
In two clinical trials, botulinum toxin injected during cystoscopy transiently prevented urinary incontinence in 1 in 5 patients but sometimes provoked urine retention and urinary tract infections.
March 2016: Prescrire International
https://www.readbyqxmd.com/read/27037973/intradetrusor-injections-of-onabotulinum-toxin-a-botox%C3%A2-300-u-or-200-u-versus-abobotulinum-toxin-a-dysport%C3%A2-750-u-in-the-management-of-neurogenic-detrusor-overactivity-a-case-control-study
#15
Benoit Peyronnet, Evelyne Castel-Lacanal, Mathieu Roumiguie, Lucie Even, Philippe Marque, Michel Soulié, Pascal Rischmann, Xavier Game
AIMS: To compare the outcomes of the first intradetrusor injections of abobotulinum toxin 750 U and onabotulinum toxin 200 and 300 U in patients with neurogenic detrusor overactivity (NDO). METHODS: A retrospective case-control study was conducted including 211 NDO patients treated in three consecutives eras with onabotulinum toxin 300 U (2004-2006; 80 patients), abobotulinum toxin 750 U (2007-2011; 78 patients) or onabotulinum toxin 200 U (2011-2014; 53 patients)...
March 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/26915654/can-botox-improve-night-time-overactive-bladder-symptoms-in-women
#16
Pawel Miotla, Rufus Cartwright, Konrad Futyma, Michal Bogusiewicz, Katarzyna Skorupska, Izabela Winkler, Tomasz Rechberger
AIMS: Despite the efficacy of intravesical onabotulinumtoxinA (Botox) therapy for urgency, urgency incontinence, and daytime frequency, its value in treatment of nocturia remains unclear. The aim of the prospective observational study was to assess the effect of onabotulinumtoxinA on night-time symptoms in women with overactive bladder (OAB), including nocturia, night-time urgency incontinence, and nocturnal voided volume as end-points. METHODS: Women with idiopathic OAB (with at least one episode of urgency urinary incontinence (UUI) per day, ≥8 micturitions per 24 hr, and ≥2 nocturia episodes per night) were enrolled...
March 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/26904413/the-role-of-botulinum-toxin-a-in-treating-neurogenic-bladder
#17
REVIEW
Filip Weckx, Manuela Tutolo, Dirk De Ridder, Frank Van der Aa
Neurogenic detrusor overactivity (NDO) can result in lower and upper urinary tract complications and eventually even in end-stage kidney failure. Since the driving force of this clinical cascade is high bladder pressure, controlling intravesical pressure in NDO patients improves both quality of life and life-expectancy in these patients. Botulinum toxin A (BTX-A) has proven its efficacy in reducing intravesical pressure and in reducing incontinence episodes. BTX-A also improves quality of life in patients with NDO...
February 2016: Translational Andrology and Urology
https://www.readbyqxmd.com/read/26866490/botulinum-toxin-to-treat-neurogenic-bladder
#18
REVIEW
Christopher P Smith, Michael B Chancellor
Alteration in neural control from suprapontine areas to the nerves innervating the bladder can lead to bladder dysfunction and the development of a neurogenic bladder (NGB). Patients with NGB often suffer from urinary incontinence, which can lead to adverse events such as urinary tract infections and decubiti, in addition to creating a large care burden for family members or healthcare providers and significantly impairing patient quality of life. The common failure of anticholinergic medications has spurned the development of second-line treatments, including the use of botulinum toxin...
February 2016: Seminars in Neurology
https://www.readbyqxmd.com/read/26824901/factors-associated-with-therapeutic-efficacy-of-intravesical-onabotulinumtoxina-injection-for-overactive-bladder-syndrome
#19
Sheng-Mou Hsiao, Ho-Hsiung Lin, Hann-Chorng Kuo
OBJECTIVES: To analyze the predictors of therapeutic efficacy after intravesical botulinum toxin A injection for overactive bladder syndrome (OAB) refractory to antimuscarinic therapy. METHODS: All consecutively OAB patients, who visited the urologic outpatient clinics of a medical center and refractory to antimuscarinic treatment, were prospectively enrolled. All enrolled patients received intravesical injection of 100 U onabotulinumtoxinA (Botox). The Global Response Assessment (GRA) score ≥ 2 at 3 months after Botox injection was defined as a successful treatment, otherwise failed...
2016: PloS One
https://www.readbyqxmd.com/read/26626215/perioperative-and-short-term-outcomes-of-robotic-vs-open-bladder-neck-procedures-for-neurogenic-incontinence
#20
Gwen M Grimsby, Micah A Jacobs, Vani Menon, Bruce J Schlomer, Patricio C Gargollo
PURPOSE: Complex urological reconstruction may be facilitated by the improved magnification and dexterity provided by a robotic approach. Minimally invasive surgery also has the potential advantages of decreased length of stay and improved convalescence. We reviewed perioperative and short-term outcomes between robot-assisted and open bladder neck sling/repair with catheterizable channel in patients with neurogenic bladder. MATERIALS AND METHODS: We performed an institutional review board approved retrospective chart review of all patients who underwent open or robotic bladder neck reconstruction without augmentation cystoplasty for refractory urinary incontinence between 2010 and 2014...
April 2016: Journal of Urology
keyword
keyword
27969
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"