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https://www.readbyqxmd.com/read/28103272/prevalence-and-determinants-of-oral-human-papillomavirus-infection-in-500-young-adults-from-italy
#1
Valentina Lupato, Dana Holzinger, Daniela Höfler, Anna Menegaldo, Paolo Giorgi Rossi, Annarosa Del Mistro, Maria Cristina Da Mosto, Michael Pawlita, Paolo Boscolo-Rizzo
Although the prevalence of human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) is increasing in developed countries and becoming a relevant health issue, the natural history of oral HPV infection is still unclear. Estimating the infection's prevalence in specific populations and identifying risk factors can widen our understanding of its natural history and help to delineate appropriate prevention strategies. This study sought to (i) determine oral HPV prevalence and genotype distribution in a large series of young Italian adults, (ii) validate an oral rinse sampling/storage protocol, and (iii) pinpoint factors associated with oral HPV infection...
2017: PloS One
https://www.readbyqxmd.com/read/28086983/mailed-hpv-self-sampling-for-cervical-cancer-screening-among-underserved-minority-women-study-protocol-for-a-randomized-controlled-trial
#2
Erin Kobetz, Julia Seay, Anthony Amofah, Larry Pierre, Jordan Baeker Bispo, Dinah Trevil, Martha Gonzalez, Martine Poitevien, Tulay Koru-Sengul, Olveen Carrasquillo
BACKGROUND: Underserved ethnic minority women experience significant disparities in cervical cancer incidence and mortality, mainly due to lack of cervical cancer screening. Barriers to Pap smear screening include lack of knowledge, lack of health insurance and access, and cultural beliefs regarding disease prevention. In our previous SUCCESS trial, we demonstrated that HPV self-sampling delivered by a community health worker (CHW) is efficacious in circumventing these barriers. This approach increased screening uptake relative to navigation to Pap smear screening...
January 13, 2017: Trials
https://www.readbyqxmd.com/read/28070251/comparison-between-vaginal-royal-jelly-and-vaginal-estrogen-effects-on-quality-of-life-and-vaginal-atrophy-in-postmenopausal-women-a-clinical-trial-study
#3
Fatemeh Seyyedi, Mahmoud Rafiean Kopaei, Sepideh Miraj
OBJECTIVE: This study was conducted to evaluate the therapeutic effects of vaginal royal jelly and vaginal estrogen on quality of life and vaginal atrophy in postmenopausal women. METHODS: This double-blind randomized controlled clinical trial was carried out at gynecology and obstetrics clinics of Hajar Hospital of Shahrekord University of Medical Sciences (Iran) from January 2013 to January 2014. The study was conducted on married postmenopausal women between 50 and 65 years old...
November 2016: Electronic Physician
https://www.readbyqxmd.com/read/28060937/barriers-to-follow-up-for-abnormal-papanicolaou-smears-among-female-sex-workers-in-lima-peru
#4
Devora Aharon, Martha Calderon, Vicky Solari, Patricia Alarcon, Joseph Zunt
BACKGROUND: Cervical cancer is the most prevalent cancer among Peruvian women. Female sex workers (FSW) in Peru are at elevated risk for HPV infection, and receive annual Papanicolaou screening. The objective of this study was to identify barriers to follow-up for abnormal Pap smears among FSW in Peru. METHODS: 97 FSW attending the Alberto Barton Health Center in Lima were surveyed regarding their STI screening history. 17 women with a history of an abnormal Pap smear were interviewed about their experiences regarding follow-up care...
2017: PloS One
https://www.readbyqxmd.com/read/28059690/accuracy-of-screening-tools-for-pap-smears-in-general-practice
#5
Catherine Harding, Alexa Seal, Louis Pilotto, Ken Mackey, Geraldine Duncan, Ronald Huynh, Robert McWilliam, Stephanie Blake
BACKGROUND: Data extraction tools (DETs) are increasingly being used for research and audit of general practice, despite their limitations.Objective This study explores the accuracy of Pap smear rates obtained with a DET compared to that of the Pap smear rate obtained with a manual file audit. METHOD: A widely available DET was used to establish the rate of Pap smears in a large multi-general practice (multi-GP) in regional New South Wales followed by a manual audit of patient files...
September 13, 2016: Journal of Innovation in Health Informatics
https://www.readbyqxmd.com/read/28029192/factors-related-to-inter-observer-reproducibility-of-conventional-pap-smear-cytology-a-multilevel-analysis-of-smear-and-laboratory-characteristics
#6
A Baena, E Guevara, M Almonte, J Arias-Stella, P Sasieni, G I Sanchez
OBJECTIVE: To identify factors that influence the inter-observer reproducibility of the routine, conventional Pap smear cytology (Pap smear test) in a network of certificated laboratories in a middle-income Latin American country. METHODS: Twenty-six laboratories provided each an average of 26 negative for malignancy (NILM) and high-grade squamous intraepithelial lesion (HSIL) Pap smears. An external panel reviewed the slides. The kappa index and multilevel logistic regression were used to estimate the reproducibility and odds ratios (OR) of a false result with 95% confidence intervals (95% CI), respectively...
December 28, 2016: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/28028296/human-papillomavirus-hpv-in-egyptian-females-study-by-cytology-histopathology-colposcopy-and-molecular-diagnosis-of-high-risk-types
#7
M A Nayel, O G Shaker, A N Hosni, H N Hosni, S E Khalifa, A F Shazly
OBJECTIVES: In Northern Africa, the region Egypt belongs to, about 10.7% of women are estimated to harbour cervical human papillomavirus (HPV) infection and 78.4% of invasive cancers are attributed to HPVs 16 or 18. We aimed at comparing HPV detection by ISH-PCR tissue with other conventional available cheaper techniques, finding which of them can be relied upon in a developing country like Egypt for HPV detection. METHODS: Sixty patients were included. For them colposcopy, PAP smear, histopathology and detection of HPV using ISH PCR tissue and PCR swab were achieved...
December 2016: Malaysian Journal of Pathology
https://www.readbyqxmd.com/read/28008671/reliability-of-reporting-the-presence-of-transformation-zone-material-in-papanicolaou-smears-using-an-automated-screening-system
#8
I Erbarut Seven, H Mollamemisoglu, F Eren
OBJECTIVE: This study was conducted to evaluate the reliability of using an interactive automated screening system (IAS) to determine the presence of endocervical and/or metaplastic cells (transformation zone material; TZM) in liquid-based cytology (LBC) Papanicolaou (Pap) smear slides. MATERIALS AND METHODS: A series of LBC Pap smears was manually screened to determine the presence or absence of TZM. The results were compared to those obtained through IAS. RESULTS: ThinPrep(®) Imaging System (Imager)-assisted screening indicated that 22...
December 23, 2016: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/28002084/use-of-visual-inspection-with-acetic-acid-pap-smear-or-high-risk-human-papillomavirus-testing-in-women-living-with-hiv-aids-for-posttreatment-cervical-cancer-screening-same-tests-different-priorities
#9
Elkanah Omenge Orang'o, Tao Liu, Astrid Christoffersen-Deb, Peter Itsura, John Oguda, Sierra Washington, David Chumba, Latha Pisharodi, Susan Cu-Uvin, Anne F Rositch
OBJECTIVES: Few studies have addressed optimal follow-up for HIV-infected women after cervical treatment. This study aimed to compare performance of three available tests to detect posttreatment cervical disease in HIV-infected women in Kenya. DESIGN: This is a prospective cohort study. METHODS: At least 6 months following cryotherapy, 517 HIV-infected women were evaluated concurrently with visual inspection with acetic acid (VIA), papanicolaou (Pap) smear, and high-risk human papillomavirus (HR-HPV) testing...
January 14, 2017: AIDS
https://www.readbyqxmd.com/read/27995101/a-comparison-of-liquid-based-cytology-with-conventional-papanicolaou-smears-in-cervical-dysplasia-diagnosis
#10
Fatemeh Haghighi, Nahid Ghanbarzadeh, Marziee Ataee, Gholamreza Sharifzadeh, Javid Shahbazi Mojarrad, Fatemeh Najafi-Semnani
BACKGROUND: Due to the high number of women affected by cervical cancer and the importance of an early diagnosis, combined with the frequent incidence of false-negative Papanicolaou (Pap) smear screening results for this disease, several studies have been conducted in recent years in order to find better tests. Liquid-based cytology (LBC) tests, including the liquid-based thin layer method, have demonstrated the highest potential for reducing false-negative cases and improved sample quality...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/27971847/new-data-on-the-burden-of-abnormal-pap-smears-and-hospitalised-pre-cancerous-lesions-in-france-egb-and-pmsi-databases-analysis
#11
L Catella, C Cancalon, A Lafourcade, Y de Rycke, S Guillo, F Tubach, M Dalichampt, A Jacquard, N Largeron, A Dahlab, M Uhart, X Bresse, C Bergeron, H Borne, S Bénard
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27941729/histological-and-cytological-correlation-of-cervical-cancer-and-precancerous-lesions-in-a-tertiary-hospital-in-bangladesh
#12
S Islam, M N Uddin, F M Saleh
Over 500,000 new cases of cervical cancer are diagnosed each year in the world, resulting in 250000 deaths. Prevalence of HPV-related cervical carcinoma in Bangladesh is highest among SAARC countries. In Bangladesh very few studies have been published on establishing the correlation between histological and cytological findings on cervical cancer and precancerous lesions. This descriptive cross-sectional study was performed to find out the correlation between histological & cytological findings of cervical cancer and precancerous lesions...
October 2016: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/27929181/smartphone-based-hand-held-quantitative-phase-microscope-using-the-transport-of-intensity-equation-method
#13
Xin Meng, Huachuan Huang, Keding Yan, Xiaolin Tian, Wei Yu, Haoyang Cui, Yan Kong, Liang Xue, Cheng Liu, Shouyu Wang
In order to realize high contrast imaging with portable devices for potential mobile healthcare, we demonstrate a hand-held smartphone based quantitative phase microscope using the transport of intensity equation method. With a cost-effective illumination source and compact microscope system, multi-focal images of samples can be captured by the smartphone's camera via manual focusing. Phase retrieval is performed using a self-developed Android application, which calculates sample phases from multi-plane intensities via solving the Poisson equation...
December 20, 2016: Lab on a Chip
https://www.readbyqxmd.com/read/27921005/primary-tuberculosis-of-cervix-a-coincidental-finding
#14
Nalini Sharma, Ahanthem Santa Singh, Yookarin Khonglah, Jaya Mishra
BACKGROUND: 95% of Tuberculosis (TB) of the female genital tract (FGT) is located in tissues other than the cervix. A rare case of primary TB of the cervix which was diagnosed coincidently in a patient of endometrioma was reported in this study. CASE PRESENTATION: A 34 year old nullipara, a diagnosed case of endometrioma had a small cervical growth. Pap smear and biopsy was taken and sent for histopathological examination. Her histopathological examination revealed multiple epitheloid cell granuloma and langerhans type giant cell caeseation...
October 2016: Journal of Reproduction & Infertility
https://www.readbyqxmd.com/read/27917772/awareness-perceived-risk-and-practices-related-to-cervical-cancer-and-pap-smear-screening-a-cross-sectional-study-among-hiv-positive-women-attending-an-urban-hiv-clinic-in-johannesburg-south-africa
#15
Idah Mokhele, D Evans, K Schnippel, A Swarts, J S Smith, C Firnhaber
BACKGROUND: Cervical cancer is a major cause of cancer-related deaths, especially in the context of the HIV epidemic. OBJECTIVE: To examine awareness, perceived risk and practices related to cervical cancer screening among HIV-positive women. METHODS: Interviewer-administered structured questionnaires were administered to HIV-positive women (aged ≥18 years) enrolled in a cervical cancer screening study at the Themba Lethu Clinic, Johannesburg, South Africa, from November 2009 to December 2011...
December 1, 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/27917752/genetic-and-environmental-factors-in-invasive-cervical-cancer-design-and-methods-of-a-classical-twin-study
#16
Dorothy A Machalek, John D Wark, Sepehr N Tabrizi, John L Hopper, Minh Bui, Gillian S Dite, Alyssa M Cornall, Marian Pitts, Dorota Gertig, Bircan Erbas, Suzanne M Garland
BACKGROUND: Persistent high-risk human papillomavirus (HPV) infection is a necessary prerequisite for development of cervical cancer and its precursor lesion, high-grade squamous intraepithelial lesion (HSIL). However, HPV infection is not sufficient to drive this process, and genetic and environmental factors may also play a role. METHODS/DESIGN: The Cervical Cancer, Genetics and Environment Twin Study was established to investigate the environmental and genetic influences on variation in susceptibility to cervical pre-cancer in 25- to 69-year-old monozygotic (MZ) and dizygotic (DZ) twins recruited through the Australian Twin Registry...
December 5, 2016: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/27906806/awareness-of-cervical-cancer-causes-and-predeterminants-of-likelihood-to-screen-among-women-in-haiti
#17
Schatzi H McCarthy, Kathy A Walmer, Joel C Boggan, Margaret W Gichane, William A Calo, Harry A Beauvais, Noel T Brewer
OBJECTIVES: Cervical cancer is the leading cause of cancer deaths among women in Haiti. Given this high disease burden, we sought to better understand women's knowledge of its causes and the sociodemographic and health correlates of cervical cancer screening. MATERIALS AND METHODS: Participants were 410 adult women presenting at clinics in Léogâne and Port-au-Prince, Haiti. We used bivariate and multivariate logic regression to identify correlates of Pap smear receipt...
January 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27894986/application-of-molecular-genotyping-to-determine-prevalence-of-hpv-strains-in-pap-smears-of-kazakhstan-women
#18
Luiza Niyazmetova, Gulzhanat Aimagambetova, Nazigul Stambekova, Zaurech Abugalieva, Korlukain Seksembayeva, Syed Ali, Azliyati Azizan
OBJECTIVES: Human papillomavirus is the main causative agent for cervical cancer. However, few data are available about HPV prevalence in Kazakhstan. The aims of this study were to genotype HPV DNA in Pap smear samples of women to determine prevalence of carcinogenic HPV types in Astana, Kazakhstan and to analyze the association between HPV positivity and the cytology results of patient samples. METHODS: Pap smear materials were obtained from 140 patients aged 18-59, who visited the outpatient gynecological clinic...
January 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/27891448/can-feulgen-stain-be-a-reliable-biomarker-over-pap-stain-for-estimation-of-micronuclei-score
#19
Manish Kumar, Umesh Chandra Prasad, Betina Chandolia, S M Manjunath, Shiva Basu, Silvie Verma
INTRODUCTION: Malignant transformation of the Potentially Malignant Lesions (PML) in the oral cavity is associated with elevated mortality rate because of its aggressive and exceedingly invasive nature. Meticulous diagnosis and prompt therapy of PML may help prevent malignant conversion in oral lesions. Carcinogenic insult to oral cells results in chromosomal damage and formation of Micronuclei (Mn), before the development of clinical symptoms. AIM: To determine the genotoxic effect of smoking and chewing tobacco on target tissue using Mn assay and to evaluate the prevalence of other nuclear anomalies associated with it and to determine the reliability of feulgen stain for Mn assay over Papaincolau (PAP) stain...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27891400/prevalence-of-human-papilloma-virus-infection-in-young-primiparous-women-during-postpartum-period-study-from-a-tertiary-care-center-in-northern-india
#20
Alpana Garg, Vanita Suri, Raje Nijhawan, Neelam Aggarwal, Ritu Aggarwal, Charu Guleria, Mili Thakur
INTRODUCTION: Assessment of high-risk Human Papilloma Virus (HPV) prevalence is important for monitoring long-term decrease in cervical cancer after implementation of the prophylactic HPV vaccination. AIM: To determine the prevalence of high-risk HPV infection and cytological abnormalities in young primiparous women in the age group of 16-26years. MATERIALS AND METHODS: In this cross-sectional study, 214 primiparous women aged 16-26years were recruited from a public tertiary health care center postpartum clinic between June 2013 and May 2014...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
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