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https://www.readbyqxmd.com/read/28067427/on-controlling-the-flow-behavior-driven-by-induction-electrohydrodynamics-in-microfluidic-channels
#1
Yanbo Li, Yukun Ren, Weiyu Liu, Xiaoming Chen, Ye Tao, Hongyuan Jiang
In this study, we develop a nondimensional physical model to demonstrate fluid flow at the micrometer dimension driven by traveling-wave induction electrohydrodynamics (EHD) through direct numerical simulation. In order to realize an enhancement in the pump flow rate as well as a flexible adjustment of anisotropy of flow behavior generated by induction EHD in microchannels, while not adding the risk of causing dielectric breakdown of working solution and material for insulation, a pair of synchronized traveling-wave voltage signals are imposed on double-sided electrode arrays that are mounted on the top and bottom insulating substrate, respectively...
January 9, 2017: Electrophoresis
https://www.readbyqxmd.com/read/28049777/preparing-fission-yeast-for-electron-microscopy
#2
Thomas H Giddings, Mary K Morphew, J Richard McIntosh
Freezing samples while simultaneously subjecting them to a rapid increase in pressure, which inhibits ice crystal formation, is a reliable method for cryofixing fission yeast. The procedure consists simply of harvesting cells and loading them into a high-pressure freezer (HPF), and then operating the device. If equipment for high-pressure freezing is not available, fission yeast can be frozen by plunging a monolayer of cells into a liquid cryogen, usually ethane or propane. Unlike the HPF, where relatively large volumes of cells can be frozen in a single run, plunge freezing requires cells to be dispersed in a layer <20 µm thick...
January 3, 2017: Cold Spring Harbor Protocols
https://www.readbyqxmd.com/read/28025831/new-daily-persistent-headache-caused-by-a-multinodular-goiter-and-headaches-associated-with-thyroid-disease
#3
Randolph W Evans, Josefine S Timm
A 33-year-old female is presented with the first case to our knowledge of new daily persistent headache (NDPH) with a large right benign non-toxic multinodular goiter causing carotid and vertebral compression with complete resolution of the headache immediately after thyroidectomy. Although this may be quite rare, hypothyroidism or hyperthyroidism causing NDPH, migraine, or an exacerbation of pre-existing migraine is not. Clinicians should consider routinely obtaining serum thyroid-stimulating hormone (TSH) and free T4 in patients with new onset frequent headaches or an exacerbation of prior primary headaches...
December 27, 2016: Headache
https://www.readbyqxmd.com/read/28024132/isolated-right-ventricular-takotsubo-cardiomyopathy-a-case-report-and-literature-review
#4
Waldemar Elikowski, Małgorzata Małek-Elikowska, Paulina Różańska, Natalia Fertała, Magdalena Zawodna
In about one quarter of patients with stress-induced takotsubo cardiomyopathy (TC) concomitant involvement of right ventricle (RV) can be observed. Opposite to this biventricular form of TC, isolated right ventricular takotsubo cardiomyopathy (RVTC) was described only in a few cases and so far has not been listed as a specific type of TC. The authors present a case of a 87-year-old demented female admitted with pneumonia in whom echocardiography revealed RV apical ballooning while the left ventricle function was quite normal...
December 22, 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27986642/anatomic-characteristics-of-the-mitral-isthmus-region-the-left-atrial-appendage-isthmus-as-a-possible-ablation-target
#5
Mateusz K Hołda, Mateusz Koziej, Jakub Hołda, Kamil Tyrak, Katarzyna Piątek, Filip Bolechała, Wiesława Klimek-Piotrowska
The mitral isthmus is a part of the postero-inferior area of the lateral left atrial wall located between the mitral annulus and the left inferior pulmonary vein ostium. Linear ablation lesions are created within the mitral isthmus for the invasive treatment of left atrial arrhythmias. However, the anatomy of this region is not fully understood. The aim of this study has been to provide a detailed morphometric description of the mitral isthmus region and to propose another possible isthmus within the investigated heart area that may serve as a potential new ablation target...
December 13, 2016: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/27984597/neurofibroma-of-the-gallbladder-not-associated-with-neurofibromatosis
#6
Tsutomu Namikawa, Yasuhiro Kawanishi, Yuki Fujieda, Kazune Fujisawa, Eri Munekage, Masaya Munekage, Hiromichi Maeda, Hiroyuki Kitagawa, Michiya Kobayashi, Kazuhiro Hanazak
An 82-year-old woman had visited her local clinic with a history of abdominal discomfort and dyspepsia related to meals over a period of several months. Esophagogastroduodenoscopy revealed a superficial spreading tumor that, on biopsy, was proven to be an adenocarcinoma, and colonoscopy revealed an ascending mass that was found to be an adenocarcinoma on biopsy, so the patient was referred to our hospital. Abdominal computed tomography revealed a mass in the ascending colon with regional lymph node swelling and a gallbladder stone measuring 1...
December 16, 2016: Surgical Technology International
https://www.readbyqxmd.com/read/27976475/regulation-of-bone-remodeling-by-vitamin-k2
#7
Vamsee D Myneni, Eva Mezey
All living tissues require essential nutrients such as amino acids, fatty acids, carbohydrates, minerals, vitamins, and water. The skeleton requires nutrients for development, maintaining bone mass and density. If the skeletal nutritional requirements are not met, the consequences can be quite severe. In recent years, there has been growing interest in promotion of bone health and inhibition of vascular calcification by Vitamin K2. This vitamin regulates bone remodeling, an important process necessary to maintain adult bone...
December 14, 2016: Oral Diseases
https://www.readbyqxmd.com/read/27931238/elaboration-of-a-nomogram-to-predict-nonsentinel-node-status-in-breast-cancer-patients-with-positive-sentinel-node-intraoperatively-assessed-with-one-step-nucleic-amplification-retrospective-and-validation-phase
#8
Franco Di Filippo, Simona Di Filippo, Anna Maria Ferrari, Raffaele Antonetti, Alessandro Battaglia, Francesca Becherini, Laia Bernet, Renzo Boldorini, Catherine Bouteille, Simonetta Buglioni, Paolo Burelli, Rafael Cano, Vincenzo Canzonieri, Pierluigi Chiodera, Alfredo Cirilli, Luigi Coppola, Stefano Drago, Luca Di Tommaso, Privato Fenaroli, Roberto Franchini, Andrea Gianatti, Diana Giannarelli, Carmela Giardina, Florence Godey, Massimo M Grassi, Giuseppe B Grassi, Siobhan Laws, Samuele Massarut, Giuseppe Naccarato, Maria Iole Natalicchio, Sergio Orefice, Fabrizio Palmieri, Tiziana Perin, Manuela Roncella, Massimo G Roncalli, Antonio Rulli, Angelo Sidoni, Corrado Tinterri, Maria C Truglia, Isabella Sperduti
BACKGROUND: Tumor-positive sentinel lymph node (SLN) biopsy results in a risk of non sentinel node metastases in micro- and macro-metastases ranging from 20 to 50%, respectively. Therefore, most patients underwent unnecessary axillary lymph node dissections. We have previously developed a mathematical model for predicting patient-specific risk of non sentinel node (NSN) metastases based on 2460 patients. The study reports the results of the validation phase where a total of 1945 patients were enrolled, aimed at identifying a tool that gives the possibility to the surgeon to choose intraoperatively whether to perform or not axillary lymph node dissection (ALND)...
December 8, 2016: Journal of Experimental & Clinical Cancer Research: CR
https://www.readbyqxmd.com/read/27896983/learning-parsimonious-ensembles-for-unbalanced-computational-genomics-problems
#9
Ana Stanescu, Gaurav Pandey
Prediction problems in biomedical sciences are generally quite difficult, partially due to incomplete knowledge of how the phenomenon of interest is influenced by the variables and measurements used for prediction, as well as a lack of consensus regarding the ideal predictor(s) for specific problems. In these situations, a powerful approach to improving prediction performance is to construct ensembles that combine the outputs of many individual base predictors, which have been successful for many biomedical prediction tasks...
2016: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/27875513/post-traumatic-trigeminal-neuropathy-caused-by-an-orbital-stab-wound
#10
Shinpei Matsuda, Hitoshi Yoshimura, Tadanori Hamano, Kazuo Sano
Sensory and motor neuropathy of the trigeminal nerve due to trauma is quite rare. Furthermore, there have been no detailed reports on occlusal abnormalities and trismus associated with post-traumatic trigeminal motor neuropathy. Here, the authors report a case of trigeminal motor neuropathy and trigeminal sensory neuropathy in all 3 divisions caused by an orbital stab wound. During kendo practice, a 61-year-old man was injured in his right medial canthus with the splinter of a broken bamboo sword. Imaging examinations did not show a brain injury or orbital bone fracture...
November 21, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27872032/web-based-antismoking-advertising-to-promote-smoking-cessation-a-randomized-controlled-trial
#11
Elad Yom-Tov, Peter Muennig, Abdulrahman M El-Sayed
BACKGROUND: Although hundreds of millions of dollars are spent each year on public health advertising, the advertisement content, design, and placement are usually developed by intuition rather than research. OBJECTIVE: The objective of our study was to develop a methodology for testing Web-based advertisements to promote smoking cessation. METHODS: We developed 10 advertisements that varied by their content (those that empower viewers to quit, help viewers to quit, or discuss the effects of smoking)...
November 21, 2016: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/27861394/bilateral-coronary-artery-fistulas-with-a-giant-coronary-aneurysm-complicated-by-aneurysm-rupture-a-case-report
#12
Hui Li, Ying Zhao, Hui-Ping Zhang, Hu Ai, Nai-Xin Zheng, Guo-Dong Tang, Fu-Cheng Sun
RATIONALE: Coronary artery aneurysms and fistulas are not rare conditions in clinical practice, but bilateral fistulas with a giant coronary aneurysm in just one person are quite rare. PATIENT CONCERNS: We report a case of a 66-year-old woman with these 2 coronary abnormalities accompanied with a huge mediastinum mass. INTERVENTIONS: The giant aneurysm was ligated and the mass was resected which was proved to be an organized hematoma finally...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27859045/roles-of-maternal-effects-in-maintaining-genetic-variation-maternal-storage-effect
#13
Masato Yamamichi, Masaki Hoso
Understanding the maintenance of genetic variation remains a central challenge in evolutionary biology. Recent empirical studies suggest the importance of temporally varying selection, as allele frequencies have been found to fluctuate substantially in the wild. However, previous theory suggests that the conditions for the maintenance of genetic variation under temporally fluctuating selection are quite restrictive. Using mathematical models, we demonstrate that maternal genetic effects, whereby maternal genotypes affect offspring phenotypes, can facilitate the maintenance of polymorphism in temporally varying environments...
November 9, 2016: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/27852187/prevention-of-breast-cancer
#14
Ian N Olver
Modifiable lifestyle factors may reduce the risk of developing breast cancer. Obesity is associated particularly with post-menopausal breast cancer. Diet is important, and exercise equivalent to running for up to 8 hours each week reduces the risk of breast cancer, both in its own right and through reducing obesity. Alcohol consumption may be responsible for 5.8% of breast cancers in Australia and it is recommended to reduce this to two standard drinks per day. Drinking alcohol and smoking increases the risk for breast cancer and, therefore, it is important to quit tobacco smoking...
November 21, 2016: Medical Journal of Australia
https://www.readbyqxmd.com/read/27833989/borderline-brenner-tumors-associated-with-ovarian-cyst-case-presentation
#15
Dinu Florin Albu, Cristina CrenguŢa Albu, Alexandru Marian Gogănău, Ştefan Dimitrie Albu, LaurenŢiu Mogoantă, Antoine Edu, Damian DiŢescu, Constantin Cristian Văduva
Borderline Brenner tumors represent quite a rare entity of ovarian tumors (about 2%) that develop from the surface ovarian epithelium. They are formed from papillary structures made of fibrovascular conjunctive axes covered by a transition epithelium, similar to the urinary bladder epithelium. According to the WHO classification, Brenner tumors present the following forms: benign, borderline and malignant. The benign ones are the most frequent, representing about 95%, the borderline represent about 5%, and the malignant ones less than 1%...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27798979/role-of-radiological-parameters-in-predicting-overall-shunt-outcome-after-ventriculoperitoneal-shunt-insertion-in-pediatric-patients-with-obstructive-hydrocephalus
#16
Devi Prasad Patra, Shyamal C Bir, Tanmoy K Maiti, Piyush Kalakoti, Hugo Cuellar, Bharat Guthikonda, Hai Sun, Christina Notarianni, Anil Nanda
OBJECTIVE Despite significant advances in the medical field and shunt technology, shunt malfunction remains a nightmare of pediatric neurosurgeons. In this setting, the ability to preoperatively predict the probability of shunt malfunction is quite compelling. The authors have compared the preoperative radiological findings in obstructive hydrocephalus and the subsequent clinical course of the patient to determine any association with overall shunt outcome. METHODS This retrospective study included all pediatric patients (age < 18 years) who had undergone ventriculoperitoneal shunt insertion for obstructive hydrocephalus...
November 2016: Neurosurgical Focus
https://www.readbyqxmd.com/read/27779846/hybrid-light-matter-states-in-a-molecular-and-material-science-perspective
#17
Thomas W Ebbesen
The notion that light and matter states can be hybridized the way s and p orbitals are mixed is a concept that is not familiar to most chemists and material scientists. Yet it has much potential for molecular and material sciences that is just beginning to be explored. For instance, it has already been demonstrated that the rate and yield of chemical reactions can be modified and that the conductivity of organic semiconductors and nonradiative energy transfer can be enhanced through the hybridization of electronic transitions...
November 15, 2016: Accounts of Chemical Research
https://www.readbyqxmd.com/read/27714956/deficiency-of-plasminogen-receptor-plg-rkt-causes-defects-in-plasminogen-binding-and-inflammatory-macrophage-recruitment-in-vivo
#18
L A Miles, N Baik, S Lighvani, S Khaldoyanidi, N M Varki, H Bai, B M Mueller, R J Parmer
BACKGROUND: Plg-RKT is a novel integral membrane plasminogen receptor that binds plasminogen via a C-terminal lysine exposed on the cell surface and promotes plasminogen activation on the cell surface by both tissue plasminogen activator and urokinase plasminogen activator. OBJECTIVES: To evaluate the role of Plg-RKT in vivo we generated Plg-RKT(-/-) mice using a homologous recombination technique. METHODS: We characterized the effect of Plg-RKT deletion on reproduction, viability, health, and spontaneous thrombosis and inflammation...
October 7, 2016: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/27701830/growth-of-magnetotactic-sulfate-reducing-bacteria-in-oxygen-concentration-gradient-medium
#19
Christopher T Lefèvre, Paul A Howse, Marian L Schmidt, Monique Sabaty, Nicolas Menguy, George W Luther, Dennis A Bazylinski
Although dissimilatory sulfate-reducing bacteria (SRB) are generally described as strictly anaerobic organisms with regard to growth, several reports have shown that some SRB, particularly Desulfovibrio species, are quite resistant to O2 . For example, SRB remain viable in many aerobic environments while some even reduce O2 to H2 O. However, reproducible aerobic growth of SRB has not been unequivocally documented. Desulfovibrio magneticus is a SRB that is also a magnetotactic bacterium (MTB). MTB biomineralize magnetosomes which are intracellular, membrane-bounded, magnetic iron mineral crystals...
October 4, 2016: Environmental Microbiology Reports
https://www.readbyqxmd.com/read/27681205/taking-actions-to-quit-chewing-betel-nuts-and-starting-a-new-life-taxi-drivers-successful-experiences-of-quitting-betel-nut-chewing
#20
Tsui-Yun Yang, Hung-Ru Lin
AIM AND OBJECTIVES: To understand taxi drivers' successful experiences of quitting betel nut chewing. BACKGROUND: Previous studies verified that betel nut chewing significantly increases the risk of oral cancer. In Taiwan, taxi drivers work for approximately 10-13 hours per day, and 31.7-80% of them choose to chew betel nuts for their invigorating qualities, which enable them to work more hours and receive more income. DESIGN: A qualitative research design was used...
September 29, 2016: Journal of Clinical Nursing
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