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https://www.readbyqxmd.com/read/28810158/a-typology-of-vaping-identifying-differing-beliefs-motivations-for-use-identity-and-political-interest-amongst-e-cigarette-users
#1
Hannah Farrimond
BACKGROUND: The aim of this study was to identify and differentiate socially shared accounts of e-cigarette use (vaping) using Q-methodology, combining factor analysis with qualitative comments. METHODS: Seventy statements on e-cigarettes, drawn from media, academic and online discussions, were sorted by participants along a continuum of agreement/disagreement, commenting on strongly ranked items. Each participant thus created their own 'account' of their vaping...
August 12, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28769840/finding-the-snarc-instead-of-hunting-it-a-20-%C3%A2-20-monte-carlo-investigation
#2
Krzysztof Cipora, Guilherme Wood
The Spatial Numerical Association of Response Codes (SNARC) effect describes a stimulus-response association of left with small magnitude and right with large magnitude. Usually, it is estimated by means of regression slopes, where the independent variable only has a limited number of levels. Inspection of the literature reveals that it is not difficult to detect a SNARC effect within a group, but it has been quite unusual to find group differences. Is the SNARC effect as it is usually estimated using regression slopes largely insensitive to group differences, and are there design parameters necessary to increase sensitivity in group comparison analyses? Using numerical simulations, we provide evidence that both sample size and the number of stimulus repetitions, as well as intra-individual variability, contribute in a substantial way to the probability of detecting an existing SNARC effect...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28748625/multiple-risk-factor-counseling-to-promote-heart-healthy-lifestyles-in-the-chest-pain-observation-unit-pilot-randomized-controlled-trial
#3
David A Katz, Mark Graber, Patricia Lounsbury, Mark W Vander Weg, Emily K Phillips, Christina Clair, Phillip A Horwitz, Xueya Cai, Alan J Christensen
OBJECTIVE: Admission to the chest pain observation unit (CPOU) may be an advantageous time for patients to consider heart-healthy lifestyle changes while undergoing diagnostic evaluation to rule out myocardial ischemia. The aim of this pragmatic trial was to assess the effectiveness of a multiple risk factor intervention in changing CPOU patients' health beliefs and readiness to change health behaviors. A secondary aim was to obtain preliminary estimates of the intervention's effect on diet, physical activity, and smoking...
July 27, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28706871/tricuspid-valve-regurgitation-after-heart-transplantation
#4
Murray H Kwon, Richard J Shemin
Tricuspid valve regurgitation (TVR) in the orthotopic heart transplant (OHT) recipient is quite common and has varied clinical sequelae. In its severest forms, it can lead to right-sided failure symptoms indistinguishable from that seen in native heart TVR disease. While certain implantation techniques are widely recognized to reduce the risk of TVR in the cardiac allograft, concomitant tricuspid annuloplasty, while having advocates, is not currently accepted as a routinely established adjunct. Decisions to surgically correct TVR in the OHT recipient must be made carefully, as certain clinical scenarios have high risk of failure...
May 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28682738/-it-would-be-easier-if-she-d-died-young-people-with-parents-with-dementia-articulating-inadmissible-stories
#5
Mel Hall, Pat Sikes
In the U.K. context where the emphasis is (quite rightly) on living well with dementia, on positivity and enabling approaches, it can be difficult for researchers to investigate and report negative experiences. Failing to re-present perceptions and experiences as they are lived, however, does a serious disservice to the research endeavor and can prevent policy and service development and positive change. In this article, we present some stories told by participants in an Alzheimer's Society (United Kingdom) Funded project uniquely investigating the perceptions and experiences of children and young people who have a parent with dementia...
July 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/28681921/now-or-never-smoking-cessation-discussions-in-the-face-of-serious-illness
#6
Clara Iversen
Sociological research on medical discussions of lifestyle suggests that smoking patients may be seen as knowingly causing their medical problems. Therefore, it may be interactionally problematic for doctors to raise the issue of smoking cessation in relation to patients' serious health problems. While a serious illness can be expected to bring to the fore the relevance of smoking cessation advice, it may also give rise to questions about patients' right to treatment. This study uses conversation analysis to explicate how patients and doctors manage issues of responsibility in smoking cessation discussions in the face of a serious medical problem that strongly correlates with smoking...
July 6, 2017: Sociology of Health & Illness
https://www.readbyqxmd.com/read/28664667/pitavastatin-up-regulate-enos-production-by-suppressing-mir-155-expression-in-lipopolysaccharide-stimulated-human-umbilical-vein-endothelial-cells
#7
Changqin Jing, Menglong Guo, Xiaodan Bao, Tianhan Li, Juntang Lin, Xinjie Lu, Wenfeng Wang
AIM: Pitavastatin (Pit) has been proved to efficiently inhibit the onset and progression of atheroscleosis. However the mechanism by which Pit exert non-lipid related effects, such as anti-inflammatory actions, is not quite clear. Our study aimed at investigating the effect of Pit on the expression of eNOS and miR-155 in LPS-stimulated HUVECs to reveal the anti-inflammatory mechanism of pitavastatin. METHODS: HUVECs were isolated from newborn umbilical cords and used in the experiments at passages 2-5...
June 30, 2017: Cardiovascular Therapeutics
https://www.readbyqxmd.com/read/28664264/behavioural-changes-sharing-behaviour-and-psychological-responses-after-receiving-direct-to-consumer-genetic-test-results-a-systematic-review-and-meta-analysis
#8
REVIEW
Kelly F J Stewart, Anke Wesselius, Maartje A C Schreurs, Annemie M W J Schols, Maurice P Zeegers
It has been hypothesised that direct-to-consumer genetic tests (DTC-GTs) could stimulate health behaviour change. However, genetic testing may also lead to anxiety and distress or unnecessarily burden the health care system. The aim is to review and meta-analyse the effects of DTC-GT on (1) behaviour change, (2) psychological response and (3) medical consumption. A systematic literature search was performed in three databases, using "direct-to-consumer genetic testing" as a key search term. Random effects meta-analyses were performed when at least two comparable outcomes were available...
June 29, 2017: Journal of Community Genetics
https://www.readbyqxmd.com/read/28640508/intraglomerular-gap-junctions-enhance-interglomerular-synchrony-in-a-sparsely-connected-olfactory-bulb-network
#9
Frederic Pouille, Thomas S McTavish, Lawrence E Hunter, Diego Restrepo, Nathan E Schoppa
KEY POINTS: Despite sparse connectivity, population-level interactions between mitral cells (MCs) and granule cells (GCs) can generate synchronized oscillations in the rodent olfactory bulb. Intraglomerular gap junctions between MCs at the same glomerulus can greatly enhance synchronized activity of MCs at different glomeruli. The facilitating effect of intraglomerular gap junctions on interglomerular synchrony is through triggering of mutually synchronizing interactions between MCs and GCs...
June 22, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28640457/primordial-like-enzymes-from-bacteria-with-reduced-genomes
#10
Matteo P Ferla, Jodi L Brewster, Kelsi R Hall, Gary B Evans, Wayne M Patrick
The first cells probably possessed rudimentary metabolic networks, built using a handful of multifunctional enzymes. The promiscuous activities of modern enzymes are often assumed to be relics of this primordial era; however, by definition these activities are no longer physiological. There are many fewer examples of enzymes using a single active site to catalyze multiple physiologically-relevant reactions. Previously, we characterized the promiscuous alanine racemase (ALR) activity of Escherichia coli cystathionine β-lyase (CBL)...
June 22, 2017: Molecular Microbiology
https://www.readbyqxmd.com/read/28600812/temporomandibular-disorders-and-dental-occlusion-a-systematic-review-of-association-studies-end-of-an-era
#11
REVIEW
D Manfredini, L Lombardo, G Siciliani
To answer a clinical research question: 'is there any association between features of dental occlusion and temporomandibular disorders (TMD)?' A systematic literature review was performed. Inclusion was based on: (i) the type of study, viz., clinical studies on adults assessing the association between TMD (e.g., signs, symptoms, specific diagnoses) and features of dental occlusion by means of single or multiple variable analysis, and (ii) their internal validity, viz., use of clinical assessment approaches to TMD diagnosis...
June 10, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28589671/pain-and-mortality-in-older-adults-the-influence-of-pain-phenotype
#12
Diane Smith, Ross Wilkie, Peter Croft, John McBeth
Objective Moderate to severe chronic pain affects one in five adults. Pain may increase the risk of mortality but the relationship is unclear. This study investigated whether mortality risk was influenced by pain phenotype, characterised by pain extent or pain impact on daily life. Methods The study population was drawn from two large population cohorts of adults aged ≥50 years; the English Longitudinal Study of Ageing (ELSA) (n=6324) and the North Staffordshire Osteoarthritis Project (NorStOP) (n=10985)...
June 7, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28585041/clinical-impact-of-mismatch-repair-protein-testing-on-outcome-of-early-staged-colorectal-carcinomas
#13
Jatin Sundersham Gandhi, Malini Goswami, Anila Sharma, Parul Tanwar, Gurudutt Gupta, Nikhil Gupta, Sunil Pasricha, Anurag Mehta, Shivender Singh, Mohit Agarwal, Nitin Gupta
INTRODUCTION: Colorectal cancer is the third most common cancer in men and second most common in women globally. In the present study, we aimed to analyse the proportion of patients with loss of immunostaining for mismatch repair (MMR) proteins in all newly diagnosed stage II cases of colorectal cancer for the purpose of prognostication, for determination of further chemotherapeutic strategy and for familial screening. METHOD: From January 2014 to December 2015, 62 consecutive newly diagnosed cases of stage II colorectal cancer were included in the study...
June 5, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28566607/development-of-extranodal-nk-t-cell-lymphoma-nasal-type-in-cerebrum-following-epstein-barr-virus-positive-uveitis
#14
Ayano Imai, Hiroshi Takase, Ken-Ichi Imadome, Go Matsuda, Iichiro Ohnishi, Kouhei Yamamoto, Takumi Kudo, Yoji Tanaka, Taketoshi Maehara, Osamu Miura, Ayako Arai
A 74-year-old woman developed bilateral uveitis with high Epstein-Barr virus (EBV) DNA load in the vitreous fluid without lymphoma cells. Four years after the onset, T2-weighted contrast-enhanced MRI revealed hyperintense lesions in the right occipital and parietal lobe. A biopsy resulted in the diagnosis of extranodal NK/T-cell lymphoma nasal type (ENKL). The repeat region of LMP1, an EBV gene, detected in the brain lesion was identical to that detected in the vitreous fluid. ENKL of the central nervous system is quite rare, and the pathogenesis has not been determined...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28556403/silver-fir-and-douglas-fir-are-more-tolerant-to-extreme-droughts-than-norway-spruce-in-south-western-germany
#15
V Vitali, U Büntgen, J Bauhus
Improving our understanding of the potential of forest adaptation is an urgent task in the light of predicted climate change. Long-term alternatives for susceptible yet economically important tree species such as Norway spruce (Picea abies) are required, if the frequency and intensity of summer droughts will continue to increase. Although Silver fir (Abies alba) and Douglas fir (Pseudotsuga menziesii) have both been described as drought-tolerant species, our understanding of their growth responses to drought extremes is still limited...
May 26, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28555834/effects-of-breeder-turnover-and-harvest-on-group-composition-and-recruitment-in-a-social-carnivore
#16
David E Ausband, Michael S Mitchell, Lisette P Waits
Breeder turnover can influence population growth in social carnivores through changes to group size, composition and recruitment. Studies that possess detailed group composition data that can provide insights about the effects of breeder turnover on groups have generally been conducted on species that are not subject to recurrent annual human harvest. We wanted to know how breeder turnover affects group composition and how harvest, in turn, affects breeder turnover in cooperatively breeding grey wolves (Canis lupus Linnaeus 1758)...
September 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28538407/unusual-jaw-metastasis-from-squamous-cell-lung-cancer-in-heavy-smoker-two-case-reports-and-review-of-the-literature
#17
REVIEW
Aldo Pezzuto, Michelangelo Morrone, Elidon Mici
RATIONALE: Jaw metastasis is a very rare condition associated with lung cancer evolution. In this paper we present two cases of patients who underwent different approach.Lung cancer is the leading cause of cancer related death worldwide. Survival depends on the staging and biology of tumor. Smoking may affect the prognosis. PATIENT CONCERNS: There are herein reported the cases of two patients affected by squamous cell lung cancer with spread to mandibular bone. DIAGNOSES: In the first case a computed tomography (CT scan) showed a large mass located in upper right lung , then bronchoscopy was performed with biopsies and the histology revealed a squamous cell carcinoma P63+ and TTF-...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28535652/-analysis-of-clinical-prognosis-and-the-correlation-between-bile-duct-injury-after-transcatheter-arterial-chemoembolization-and-the-level-of-hepatic-arterial-embolization-in-patients-with-hepatocellular-carcinoma
#18
H Y Xu, X P Yu, R Feng, H J Hu, W W Xiao
Objective: To evaluate the correlation between bile duct injury after transcatheter arterial chemoembolization and the level of hepatic arterial embolization, and to analyze the clinical prognosis of hepatocellular carcinoma patients. Methods: From January18, 2012 to December18, 2014, 21 patients underwent TACE for HCC were retrospectively reviewed, including patients' clinical and pathological data. The clinical outcome and relevant factors for bile duct injury were analyzed. Results: A total of 21 patients were identified with bile duct injury at our single institution...
May 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28524272/frontal-sinus-development-and-juvenile-age-estimation
#19
Kaitlin Moore, Ann Ross
Assessment of development is an important component of age estimation in juveniles. One area that has not been fully investigated as a possible aging method is the development of the frontal sinus. The frontal sinuses form when the ectocranial table of the frontal bone separates from the endocranial table forming an air pocket in the bone. The endocranial table ceases growth with the brain, while the ectocranial table is displaced anteriorly as the facial bones continue growth. In order to examine growth and the utility of the frontal sinuses for age estimation, 392 radiographs were examined (♀=159 and ♂=233) from the Juvenile Radiograph Database at North Carolina State University and the Patricia Database from Mercyhurst University...
May 19, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28493616/descriptive-title-impact-of-a-webcast-on-nurses-delivery-of-tobacco-dependence-treatment
#20
Linda Sarna, Stella Aguinaga Bialous, Marjorie Wells, Jenny Brook
AIMS AND OBJECTIVES: The aims were to evaluate an educational program about nurses' role in tobacco dependence treatment, and its webcast component, on the long-term impact of increasing the frequency of nurses' self-reported changes in practice related to delivery of smoking cessation interventions. BACKGROUND: Healthcare professionals' knowledge about evidence-based tobacco dependence treatment using the 5As framework (Ask about tobacco use, Advise users to quit, Assess willingness to quit, Assist in making a quit plan, and Arrange for follow-up, including referral to a quitline) is essential to increase smoking cessation rates in the United States...
May 11, 2017: Journal of Clinical Nursing
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