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https://www.readbyqxmd.com/read/28727724/grandmothering-and-cognitive-resources-are-required-for-the-emergence-of-menopause-and-extensive-post-reproductive-lifespan
#1
Carla Aimé, Jean-Baptiste André, Michel Raymond
Menopause, the permanent cessation of ovulation, occurs in humans well before the end of the expected lifespan, leading to an extensive post-reproductive period which remains a puzzle for evolutionary biologists. All human populations display this particularity; thus, it is difficult to empirically evaluate the conditions for its emergence. In this study, we used artificial neural networks to model the emergence and evolution of allocation decisions related to reproduction in simulated populations. When allocation decisions were allowed to freely evolve, both menopause and extensive post-reproductive life-span emerged under some ecological conditions...
July 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28724413/smoking-related-general-and-cause-specific-mortality-in-estonia
#2
Gea Kõks, Krista Fischer, Sulev Kõks
BACKGROUND: Tobacco smoking is known to be the single largest cause of premature death worldwide. The aim of present study was to analyse the effect of smoking on general and cause-specific mortality in the Estonian population. METHODS: The data from 51,756 adults in the Estonian Genome Center of the University of Tartu was used. Information on dates and causes of death was retrieved from the National Causes of Death Registry. Smoking status, general survival, general mortality and cause-specific mortality were analysed using Kaplan-Meier estimator and Cox proportional hazards models...
July 19, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28719808/activated-neuro-oxidative-and-neuro-nitrosative-pathways-at-the-end-of-term-are-associated-with-inflammation-and-physio-somatic-and-depression-symptoms-while-predicting-outcome-characteristics-in-mother-and-baby
#3
Chutima Roomruangwong, Decio Sabbatini Barbosa, Andressa Keiko Matsumoto, André de Souza Nogueira, Buranee Kanchanatawan, Sunee Sirivichayakul, André F Carvalho, Sebastien Duleu, Michel Geffard, Estefania Gastaldello Moreira, Michael Maes
OBJECTIVES: To examine oxidative & nitrosative stress (O&NS) biomarkers at the end of term in relation to perinatal affective symptoms, neuro-immune biomarkers and pregnancy-related outcome variables. METHODS: We measured plasma advanced oxidation protein products (AOPP), nitric oxide metabolites (NOx), total radical trapping antioxidant parameter (TRAP), -sulfhydryl (-SH), peroxides (LOOH) and paraoxonase (PON)1 activity in pregnant women with and without prenatal depression and non-pregnant controls...
July 6, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28719349/identification-of-g2607a-mutation-in-egfr-gene-with-a-significative-rate-in-moroccan-patients-with-bladder-cancer
#4
W El Hamdani, K Hadami, M Bensaid, H El Ahanidi, A Ameur, A Filali Maltouf, M Abbar, M Attaleb, A Albouzidi, M El Mzibri
The epidermal growth factor receptor (EGFR) is involved in the regulation of several cellular processes and in the development of many human cancers. Somatic mutations of EGFR at tyrosine kinase domain have been associated with clinical response to tyrosine kinase inhibitors (TKIs) in lung cancer patients. In this study, we evaluated the frequency of point mutations in EGFR for future use of TKI in clinical treatment of bladder cancer. A total, 50 Moroccan patient specimens with bladder cancer and 48 healthy controls were analysed for EGFR mutations in the region delimiting exons 18-21 by PCR amplification and direct sequencing...
May 20, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28707502/appraisal-of-the-psychiatric-diagnostic-screening-questionnaire-in-a-perinatal-cohort-the-apron-study
#5
Brenda Leung, Nicole Letourneau, Katherine Bright, Gerald F Giesbrecht, Henry Ntanda, Lisa Gagnon
BACKGROUND: Depression and anxiety are routinely screened as part of perinatal care. However, other Axis 1 disorders and specific anxiety disorders are less likely to be screened or assessed as part of obstetric care. The objective of this study was to determine whether the Psychiatric Diagnostic Screening Questionnaire (PDSQ) is a potentially useful tool to screen for psychiatric conditions in pregnant and postpartum women in a community setting. METHODS: We compared the prevalence of DSM Axis I disorders obtained on the PDSQ with: (1) the prevalence of these disorders reported in previous studies of pregnant and postpartum women, and (2) scores obtained on the Edinburgh Postpartum Depression Scale (EPDS) and the Symptom Checklist-90-Revised (SCL-90R) anxiety scale...
July 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28707491/the-effect-of-omega-3-fatty-acid-supplementation-on-premenstrual-syndrome-and-health-related-quality-of-life-a-randomized-clinical-trial
#6
Samira Behboudi-Gandevani, Fatemeh-Zahra Hariri, Lida Moghaddam-Banaem
INTRODUCTION: Most reproductive aged women suffer from somatic and mental disorders prior to menstruation. This study investigated whether omega-3 supplement improved premenstrual symptoms and health-related quality of life among reproductive aged women. METHODS: A multi-center, balanced (1:1), placebo-controlled, parallel-group randomized clinical trial was conducted in an urban academic institution. A sample consisting of 95 Iranian women aged 20-35 years who were suffering from premenstrual symptoms were randomly allocated into two groups...
July 14, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28706734/brca1-and-brca2-mutations-and-treatment-strategies-for-breast-cancer
#7
Inês Godet, Daniele M Gilkes
Breast cancer is a global burden with a woman's lifetime risk of developing breast cancer at 1 in 8. Although breast cancer is a disease that affects mostly women, the lifetime risk in men is about 1 in 1000. Most cases of breast cancer are associated with somatic mutations in breast cells that are acquired during a person's lifetime. In this scenario, the mutations are not inherited and they do not cluster in families. In hereditary breast cancer, the specific genetic factors involved will determine the inherited cancer risk...
February 2017: Integrative Cancer Science and Therapeutics
https://www.readbyqxmd.com/read/28706562/psychological-health-and-religious-coping-of-ghanaian-women-with-infertility
#8
Mabel Oti-Boadi, Kwaku Oppong Asante
BACKGROUND: Infertility has been shown to have considerable psychological effects on the well-being of couples, especially women. Religion has been found as a resource used by infertile women to cope with their distress. Little research has examined the influence of religious coping on psychological distress among infertile women in Ghana. This study examines the relationship between positive and negative religious coping and psychological health for women with infertility problems in Ghana...
2017: BioPsychoSocial Medicine
https://www.readbyqxmd.com/read/28705783/correction-of-abdominal-distension-by-biofeedback-guided-control-of-abdomino-thoracic-muscular-activity-in-a-randomized-placebo-controlled-trial
#9
Elizabeth Barba, Anna Accarino, Fernando Azpiroz
BACKGROUND & AIMS: Abdominal distension is produced by abnormal somatic postural tone; we developed an original biofeedback technique based on electromyography-guided control of abdomino-thoracic muscular activity. We performed a randomized, placebo-controlled study demonstrate the superiority of biofeedback to placebo for the treatment of abdominal distension. METHODS: At a referral center in Spain, we enrolled consecutive patients with visible abdominal distension who fulfilled the Rome III criteria for functional intestinal disorders (47 women, 1 man; 21-74 yrs old); 2 patients assigned to the placebo group withdrew and 2 patients assigned to biofeedback were not valid for analysis...
July 10, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28697094/identifying-and-assisting-sexually-exploited-and-trafficked-patients-seeking-women-s-health-care-services
#10
Erin E Tracy, Wendy Macias-Konstantopoulos
It is estimated that 21 million people are trafficked worldwide, including 11.4 million women and girls. Approximately 4.5 million are forced to do sexual labor. The exact prevalence of human trafficking is difficult to ascertain, however, given the limitations of data collection in an illegal industry. Obstetrician-gynecologists should not only be aware of the widespread nature of human trafficking, but also have the tools to assess patients for trafficking and respond to victim identifications. Patients may present with signs of physical abuse, depression, anxiety, posttraumatic stress disorder, substance use, sexually transmitted infections, pregnancy, and nonspecific somatic complaints...
July 7, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28688824/white-matter-lesions-are-associated-with-specific-depressive-symptom-trajectories-among-incident-depression-and-dementia-populations-three-city-dijon-mri-study
#11
Phillip J Tully, Stephanie Debette, Bernard Mazoyer, Christophe Tzourio
OBJECTIVE: Evidence is mixed as to whether periventricular or deep white matter hyperintensities (WMHs) increase the risk for depressive symptoms, partly because of heterogeneity in depression measurement, short follow-up, and confounding by prodromal dementia. The study objective was to evaluate WMH volume in relation to discrete depressive symptoms over 10 years, stratifying by incident depression and dementia. METHODS: In this prospective longitudinal cohort study of a representative population sample from Dijon, France, 1,440 participants aged 65-80 years (median age: 72 years; 59...
July 5, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28687082/experiences-of-inequitable-care-among-afghan-mothers-surviving-near-miss-morbidity-in-tehran-iran-a-qualitative-interview-study
#12
Soheila Mohammadi, Aje Carlbom, Robabeh Taheripanah, Birgitta Essén
BACKGROUND: Providing equitable maternal care to migrants is a seriously challenging task for hosting countries. Iran, the second-most accessed country for refugees from Afghanistan, has achieved maternal health improvement. However, Afghan women with near-miss morbidity faced pre-hospital delays and disparity in maternal care at hospitals. This study explores experiences of maternal care among Afghan women surviving near-miss morbidity to increase insight into healthcare improvements for migrants...
July 7, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28683025/visceral-pain-as-a-triggering-factor-for-fibromyalgia-symptoms-in-comorbid-patients
#13
Raffaele Costantini, Giannapia Affaitati, Ursula Wesselmann, Peter Czakanski, Maria Adele Giamberardino
Fibromyalgia (FMS) is a central sensitization syndrome, however peripheral pain sources potentially exacerbate its symptoms of chronic diffuse musculoskeletal pain and hyperalgesia. This prospective study evaluated visceral pain as a possible triggering factor for FMS pain/hyperalgesia in comorbid patients. Women with: a) FMS+irritable bowel syndrome (IBS); b) FMS+primary dysmenorrhea (Dys); c) FMS+dysmenorrhea secondary to endometriosis (Endo); d) FMS+colon diverticulosis (Div) were compared with FMS-only women, for fibromyalgia pain (number/intensity of episodes, analgesic consumption) over comparable time periods and for somatic hyperalgesia (electrical/pressure pain thresholds) in painful (Tender Points, TePs) and control areas (trapezius, deltoid, quadriceps muscles and overlying subcutis and skin)...
July 3, 2017: Pain
https://www.readbyqxmd.com/read/28680305/alexithymia-and-somatization-in-depressed-patients-the-role-of-the-type-of-somatic-symptom-attribution
#14
Okan Taycan, Armağan Özdemir, Serap Erdoğan Taycan
INTRODUCTION: This study aimed to establish the association between alexithymia and various factors, mainly somatization, and to determine the predictors of alexithymia in depressed patients. METHODS: A total of 90 patients with major depressive disorder who met The Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition (DSM-IV) diagnostic criteria were administered the Toronto Alexithymia Scale (TAS), Beck Depression Inventory, Symptom Checklist-90 (SCL-90), Somatosensory Amplification Scale, and Symptom Interpretation Questionnaire...
June 2017: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/28679309/long-term-effects-of-premature-birth-on-somatic-development-in-women-through-adolescence-and-adulthood
#15
Katarzyna Kaczmarczyk, Aleksandra Pituch-Zdanowska, Ida Wiszomirska, Andrzej Magiera, Aleksander Ronikier
Objectives To evaluate the long-term consequences of preterm birth on anthropometric parameters in women in adolescence and into adulthood. Methods Seventy girls born preterm (age 12.22 ± 1.52 years) and 48 born at term participated in the first stage. Eighteen years later, 13 of the same women participated in a follow-up and were compared with a control group of 27 women. We compared anthropometric results across the two examinations, and in the second stage, also assessed body composition using bioelectrical impedance analysis...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28676082/cell-sex-affects-extracellular-matrix-protein-expression-and-proliferation-of-smooth-muscle-progenitor-cells-derived-from-human-pluripotent-stem-cells
#16
Yanhui Li, Yan Wen, Morgaine Green, Elise K Cabral, Prachi Wani, Fan Zhang, Yi Wei, Thomas M Baer, Bertha Chen
BACKGROUND: Smooth muscle progenitor cells (pSMCs) differentiated from human pluripotent stem cells (hPSCs) hold great promise for treating diseases or degenerative conditions involving smooth muscle pathologies. However, the therapeutic potential of pSMCs derived from men and women may be very different. Cell sex can exert a profound impact on the differentiation process of stem cells into somatic cells. In spite of advances in translation of stem cell technologies, the role of cell sex and the effect of sex hormones on the differentiation towards mesenchymal lineage pSMCs remain largely unexplored...
July 4, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28673380/possible-adverse-effects-of-the-quadrivalent-human-papillomavirus-vaccine-in-the-region-of-southern-denmark-a-retrospective-descriptive-cohort-study
#17
Cecilie Cramon, Christina Lindegaard Poulsen, Ulla Birgitte Hartling, Inge Kristine Holden, Isik Somuncu Johansen
INTRODUCTION: Since the introduction of the quadrivalent human papillomavirus vaccine, young girls and women have reported a broad range of symptoms. These have been described as possible adverse effects of the vaccine. In this study, we describe demographic characteristics, symptomatology, clinical and laboratory test results in patients referred with suspected adverse effects in the Region of Southern Denmark. METHODS: We conducted a retrospective, descriptive study...
July 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/28671276/love-and-melancholia-in-the-analysis-of-women-by-women
#18
Rosine Jozef Perelberg
This paper suggests that in the analysis of women by women a melancholic core may be encountered at the centre of the transference/countertransference situation that is an expression of the loss of the primary maternal object that has never been mourned. The attachment to the primary, lost object may be preserved in a melancholic, invisible way, and the longing that it is connected to might only reach representation in the après coup of the analytic process. The links between this primary love, melancholia and the unrepresentable in the analysis of women will be explored...
July 3, 2017: International Journal of Psycho-analysis
https://www.readbyqxmd.com/read/28669226/usage-of-healthcare-services-and-preference-for-mental-healthcare-among-older-somali-immigrants-in-finland
#19
Mulki Mölsä, Marja Tiilikainen, Raija-Leena Punamäki
OBJECTIVES: The aims of the study were, first, to describe and analyze healthcare services utilization patterns of older immigrants in Finland, and particularly to compare the availability and accessibility of health services between older Somalis and Finns. The second aim was to examine the preferences for mental healthcare within the group of Somalis. The third aim was to test the existence of a service usage gap expected to be characteristic of the Somali group, in which high levels of mental health problems occur alongside simultaneous low levels of mental health service usage...
July 3, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/28667469/reliability-validity-and-factor-structure-of-the-hopkins-symptom-checklist-25-population-based-study-of-persons-living-with-hiv-in-rural-uganda
#20
Scholastic Ashaba, Bernard Kakuhikire, Dagmar Vořechovská, Jessica M Perkins, Christine E Cooper-Vince, Samuel Maling, David R Bangsberg, Alexander C Tsai
Depression and anxiety are highly comorbid among people living with HIV (PLHIV), but few instruments for screening or measurement have been validated for use in sub-Saharan Africa. The objective of this study was to determine the reliability, validity, and factor structure of the 25-item Hopkins Symptom Checklist (HSCL) in a population-based sample of PLHIV in rural Uganda. This study was nested within an ongoing population-based cohort of all residents living in Nyakabare Parish, Mbarara District, Uganda. All participants who identified as HIV-positive by self-report were included in this analysis...
June 30, 2017: AIDS and Behavior
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