keyword
MENU ▼
Read by QxMD icon Read
search

Somatization women

keyword
https://www.readbyqxmd.com/read/29132562/breast-cancer-disparities-how-can-we-leverage-genomics-to-improve-outcomes
#1
REVIEW
Melissa B Davis, Lisa A Newman
Breast cancer mortality rates are higher in African American compared with white American women. Disproportionately rising incidence rates, coupled with higher rates of biologically aggressive disease among African Americans is resulting in a widening of the mortality disparity. Higher rates of triple-negative breast cancer among African American women, as well as women from western sub-Saharan Africa, has prompted questions regarding the role of African ancestry as a marker of hereditary susceptibility for specific disease phenotypes...
January 2018: Surgical Oncology Clinics of North America
https://www.readbyqxmd.com/read/29130051/the-effect-of-a-12-week-health-training-program-on-selected-anthropometric-and-biochemical-variables-in-middle-aged-women
#2
Wanda Pilch, Łukasz Tota, Ewa Sadowska-Krępa, Anna Piotrowska, Magdalena Kępińska, Tomasz Pałka, Adam Maszczyk
Regular moderate physical activity positively affects health, fitness, and body composition; it regulates the pro- and anti-inflammatory cytokines levels. Vitamin D plays an important regulatory role; its adequate levels correlate with low values of inflammation markers and an increase in muscle strength and fitness in exercising people. The study's aim was to evaluate changes in somatic variables, oxidative stress, and inflammation markers, as well as blood calcidiol concentration in middle-aged healthy women after 12 weeks of aerobics classes-endurance exercises, including choreographic sequences, aiming to improve fitness and motor coordination...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29121892/correlates-of-depressive-symptoms-in-late-middle-aged-taiwanese-women-findings-from-the-2009-taiwan-national-health-interview-survey
#3
Kun-Wei Tsai, Shih-Chun Lin, Malcolm Koo
BACKGROUND: Previous studies have shown that depressive symptoms in middle-aged women were associated with a number of factors such as climacteric symptoms. Nevertheless, studies based on population-based data with a wide range of potential correlates are still scarce. Therefore, the aim of this study was to investigate the correlates of depressive symptoms in late middle-aged Taiwanese women using data from a nationally-representative, population-based survey. METHODS: Women aged 50...
November 9, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/29117876/the-role-of-gender-and-anxiety-in-the-association-between-somatic-diseases-and-depression-findings-from-three-combined-epidemiological-studies-in-primary-care
#4
E Asselmann, J Venz, L Pieper, H-U Wittchen, D Pittrow, K Beesdo-Baum
AIMS: Although associations between various somatic diseases and depression are well established, findings concerning the role of gender and anxiety disorders for these associations remain fragmented and partly inconsistent. Combining data from three large-scaled epidemiological studies in primary care, we aim to investigate interactions of somatic diseases with gender and anxiety disorders in the association with depression. METHODS: Self-reported depression according to the International Classification of Diseases, Tenth Edition (ICD-10) was assessed in n = 83 737 patients from three independent studies [DETECT (Diabetes Cardiovascular Risk Evaluation: Targets and Essential Data for Commitment of Treatment), Depression-2000 and Generalized Anxiety and Depression in Primary Care (GAD-P)] using the Depression Screening Questionnaire (DSQ)...
November 9, 2017: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/29117210/quality-of-life-and-impact-of-pain-in-women-treated-with-aromatase-inhibitors-for-breast-cancer-a-multicenter-cohort-study
#5
Françoise Laroche, Serge Perrot, Terkia Medkour, Paul-Henri Cottu, Jean-Yves Pierga, Jean-Pierre Lotz, Karine Beerblock, Christophe Tournigand, Laure Chauvenet, Didier Bouhassira, Joël Coste
Women with hormone-dependent breast cancer are treated with aromatase inhibitors (AI) to slow disease progression by decreasing estrogen levels. However, AI have adverse effects, including pain, with potentially serious impact on quality of life (QOL) and treatment compliance. We evaluated quality of life during the first year of AI treatment, focusing particularly on the impact of pain. In a multicenter cohort study of 135 women with early-stage breast cancer, free of pain at the initiation of AI treatment, quality of life (by the EORTC QLQ-BR23), somatic and psychic symptoms, psychological characters, temperament and coping strategies were assessed at baseline and at each follow-up visit (1, 3, 6 and 12 months)...
2017: PloS One
https://www.readbyqxmd.com/read/29116469/brca1-deficiency-is-a-recurrent-event-in-early-onset-triple-negative-breast-cancer-a-comprehensive-analysis-of-germline-mutations-and-somatic-promoter-methylation
#6
Rafael Canfield Brianese, Kivvi Duarte de Mello Nakamura, Fernanda Gabriella Dos Santos Ramos de Almeida, Rodrigo Fernandes Ramalho, Bruna Durães de Figueiredo Barros, Elisa Napolitano E Ferreira, Maria Nirvana da Cruz Formiga, Victor Piana de Andrade, Vladmir Claudio Cordeiro de Lima, Dirce Maria Carraro
PURPOSE: BRCA1 germline mutation is closely associated with triple-negative breast cancer. BRCA deficiency leads to impaired DNA repair and tumor development, and understanding this deficiency, in both hereditary and sporadic scenarios, is of great clinical and biological interest. Here, we investigated germline or somatic events that might lead to BRCA1 impairment in triple-negative breast cancer. We also analyzed the clinical implications associated with BRCA deficiency. METHODS: Next-generation sequencing for the BRCA1/2 genes and multiplex ligation-dependent probe amplification (MLPA) for the BRCA1 gene were performed for mutation screening...
November 7, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29105808/early-childhood-adversities-and-risk-of-eating-disorders-in-women-a-danish-register-based-cohort-study
#7
Janne Tidselbak Larsen, Trine Munk-Olsen, Cynthia M Bulik, Laura M Thornton, Susanne Vinkel Koch, Preben Bo Mortensen, Liselotte Petersen
OBJECTIVE: Previous studies evaluating the association between early childhood adversities and eating disorders have yielded conflicting results. The aim of this study is to examine the association between a range of adversities and risk of anorexia nervosa (AN), bulimia nervosa (BN), and eating disorder not otherwise specified (EDNOS) in 495,244 women. METHOD: In this nationwide, register-based cohort study, nine types of early childhood adversity (family disruption, residential instability, placement in out-of-home care, familial death, parental somatic illness, parental psychiatric illness, parental disability, severe parental criminality, and parental substance use disorder) were defined and exposure during the first 6 years of life was determined...
November 6, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29105043/quality-of-life-among-postmenopausal-women-in-rural-minia-egypt
#8
Nashwa N Kamal, Amany E Seedhom
This study aimed to determine the prevalence and severity of menopausal symptoms and their effect on the quality of life of postmenopausal women in rural Minia. A cross-sectional study was conducted among 1 100 postmenopausal women aged 45-60 years selected by multistage random sampling. The menopause rating scale (MRS) was used to assess the menopausal symptoms. The mean age at menopause was 48.9 (SD 4) years. The most frequent symptoms were joint and muscle pain (82.1%), physical and mental exhaustion (69...
October 30, 2017: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29102090/comprehensive-genomic-profiling-reveals-inactivating-smarca4-mutations-and-low-tumor-mutational-burden-in-small-cell-carcinoma-of-the-ovary-hypercalcemic-type
#9
Douglas I Lin, Yakov Chudnovsky, Bridget Duggan, Deborah Zajchowski, Joel Greenbowe, Jeffrey S Ross, Laurie M Gay, Siraj M Ali, Julia A Elvin
OBJECTIVE: Small cell carcinoma of the ovary, hypercalcemic-type (SCCOHT) is a rare, extremely aggressive neoplasm that usually occurs in young women and is characterized by deleterious germline or somatic SMARCA4 mutations. We performed comprehensive genomic profiling (CGP) to potentially identify additional clinically and pathophysiologically relevant genomic alterations in SCCOHT. METHODS: CGP assessment of all classes of coding alterations in up to 406 genes commonly altered in cancer and intronic regions for up to 31 genes commonly rearranged in cancer was performed on 18 SCCOHT cases (16 exhibiting classic morphology and 2 cases exhibiting exclusive a large cell variant morphology)...
October 25, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/29099752/reproductive-investment-and-health-costs-in-roma-women
#10
Jelena Čvorović, Kathryn Coe
In this paper, we examine whether variation in reproductive investment affects the health of Roma women using a dataset collected through original anthropological fieldwork among Roma women in Serbia. Data were collected in 2014-2016 in several Roma semi-urban settlements in central Serbia. The sample consisted of 468 Roma women, averaging 44 years of age. We collected demographic data (age, school levels, socioeconomic status), risk behaviors (smoking and alcohol consumption), marital status, and reproductive history variables (the timing of reproduction, the intensity of reproduction, reproductive effort and investment after birth), in addition to self-reported health, height, and weight...
November 3, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29095126/experiencing-menopause-in-the-uk-the-interrelated-narratives-of-normality-distress-and-transformation
#11
Isabel de Salis, Amanda Owen-Smith, Jenny L Donovan, Debbie A Lawlor
We investigated the experience and perspectives of menopause among 48 UK mothers through qualitative in-depth interviews. Interviews were analyzed thematically then explored using social science theories. Three interdependent narratives emerged: menopause as a normal, biological process, distinct from self and social transitions; menopause as struggle, an "idiom of distress" expressing upset, identity loss, shame, and social upheaval; and menopause as transformative and liberating, arising from biopsychic and relational changes...
November 2, 2017: Journal of Women & Aging
https://www.readbyqxmd.com/read/29094789/relationship-between-symptoms-and-quality-of-life-in-fecal-incontinence
#12
K Bedard, S Heymen, O S Palsson, A E Bharucha, W E Whitehead
BACKGROUND: Most measures of fecal incontinence (FI) severity assess the frequency of solid and liquid FI, but may incorporate other features. We compared two scales-the Fecal Incontinence Severity Score (FISS) and Fecal Incontinence Severity Index (FISI)-to determine which questionnaire and which individual questions predict FI Quality of Life (FIQOL). METHODS: A national sample of American adults completed a health questionnaire, and 234 with monthly FI were selected...
November 2, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29092048/intragenomic-conflict-and-immune-tolerance-do-selfish-x-linked-alleles-drive-skewed-x-chromosome-inactivation
#13
Scott W Roy
In mammalian females, diploid somatic cells contain two X chromosomes, one of which is transcriptionally silenced, in a process termed X chromosome inactivation (XCI). While XCI is largely random in placental females, many women exhibit skewed XCI (SXCI), in which the vast majority cells have the same X chromosome inactivated. SXCI has serious health consequences, associated with conditions ranging from Alzheimer's to various autoimmune disorders. SXCI is also associated with outcomes of pregnancies, with higher rates of recurrent spontaneous abortion in women with SXCI...
October 30, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/29076404/somatic-symptom-presentations-in-women-with-fibromyalgia-are-differentially-associated-with-elevated-depression-and-anxiety
#14
Katherine Hadlandsmyth, Dana L Dailey, Barbara A Rakel, M Bridget Zimmerman, Carol Gt Vance, Ericka N Merriwether, Ruth L Chimenti, Katharine M Geasland, Leslie J Crofford, Kathleen A Sluka
This study examined whether depression and anxiety differentially relate to fatigue, sleep disturbance, pain catastrophizing, fear of movement, and pain severity in women with fibromyalgia. Baseline data from the Fibromyalgia Activity Study with Transcutaneous Electrical Nerve Stimulation were analyzed. Of 191 participants, 50 percent reported high anxiety and/or depression (17% high anxiety, 9% high depression, and 24% both). Fatigue and sleep impairment were associated with high depression ( p < 0...
October 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/29074543/association-between-lung-cancer-somatic-mutations-and-occupational-exposure-in-never-smokers
#15
Christophe Paris, Pascal Do, Bénédicte Mastroianni, Adrien Dixmier, Patrick Dumont, Eric Pichon, Christos Chouaid, Bruno Coudert, Pascal Foucher, Séverine Fraboulet, Myriam Locatelli-Sanchez, Nathalie Baize, Eric Dansin, Lionel Moreau, Michel Vincent, Pascale Missy, Franck Morin, Denis Moro-Sibilot, Sébastien Couraud
Occupational exposure constitutes a common risk factor for lung cancer. We observed molecular alterations in 73% of never-smokers, 35% of men and 8% of women were exposed to at least one occupational carcinogen. We report herein associations between molecular patterns and occupational exposure.BioCAST was a cohort study of lung cancer in never-smokers that reported risk factor exposure and molecular patterns. Occupational exposure was assessed via a validated 71-item questionnaire. Patients were categorised into groups that were unexposed and exposed to polycyclic aromatic hydrocarbons (PAH), asbestos, silica, diesel exhaust fumes (DEF), chrome and paints...
October 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29074062/the-role-of-psychological-factors-in-the-development-of-burning-mouth-syndrome
#16
H S Yoo, S H Jin, Y J Lee, C M Song, Y B Ji, K Tae
The psychiatric profiles of 50 patients diagnosed with burning mouth syndrome (BMS) were compared to those of 50 age- and sex-matched individuals as the control group. The Symptom Checklist-90-Revised (SCL-90-R) questionnaire was used to evaluate the role of psychological factors in the development of BMS. Somatization, obsessive-compulsive, depression, anxiety, hostility, phobic anxiety, psychoticism, global severity index (GSI), positive symptom total (PST), and positive symptom distress index (PSDI) scores were significantly higher in the patients with BMS than in the control group...
October 23, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29073819/evaluation-of-hair-cortisol-and-cortisone-change-during-pregnancy-and-the-association-with-self-reported-depression-somatization-and-stress-symptoms
#17
Friederike Scharlau, Diana Pietzner, Mandy Vogel, Alexander Gaudl, Uta Ceglarek, Joachim Thiery, Jürgen Kratzsch, Andreas Hiemisch, Wieland Kiess
Hair cortisol levels are used to measure long-term stress, while its inactive metabolite cortisone is often not assessed. We measured hair cortisol concentrations (HCC) and hair cortisone concentrations (HCNC) via liquid chromatography quadrupole linear ion trap mass spectrometry (LC-MS(3)) in 62 pregnant women who participated in the LIFE CHILD STUDY in their 2nd and 3rd trimester between 12/2011 and 11/2014. Sociodemographic factors, pregnancy-related factors, and hair characteristics were assessed. Degree of severity of depression, somatization, and stress were evaluated in both trimesters with a self-reported Patient Health Questionnaire (PHQ)...
October 26, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29071455/assessment-of-significant-psychological-distress-at-the-end-of-pregnancy-and-associated-factors
#18
L Lorén-Guerrero, A Gascón-Catalán, D Pasierb, M A Romero-Cardiel
The aim of this study is to study the prevalence of mental distress at the end of pregnancy and after birth and the impact of selected socio-demographic and obstetric factors. This is a cross-sectional study. The sample is consisted of 351 puerperal women at the age of 18 and over. Sociodemographic, obstetric variables were collected to detect significant psychological distress; the instrument used was General Health Questionnaire (GHQ-28). Logistic multivariable regressions were used to investigate associations...
October 25, 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/29061645/homologous-recombination-dna-repair-pathway-disruption-and-retinoblastoma-protein-loss-are-associated-with-exceptional-survival-in-high-grade-serous-ovarian-cancer
#19
Dale W Garsed, Kathryn Alsop, Sian Fereday, Catherine Emmanuel, Catherine Kennedy, Dariush Etemadmoghadam, Bo Gao, Val Gebski, Valérie Garès, Elizabeth L Christie, Maartje Ca Wouters, Katy Milne, Joshy George, Ann-Marie Patch, Jason Li, Gisela Mir Arnau, Timothy Semple, Sreeja R Gadipally, Yoke-Eng Chiew, Joy Hendley, Thomas Mikeska, Giada V Zapparoli, Kaushalya Amarasinghe, Sean Grimmond, John V Pearson, Nicola Waddell, Jillian Hung, Colin J R Stewart, Raghwa Sharma, Prue E Allan, Peter F Rambau, Nadia Traficante, Orla McNally, Linda Mileshkin, Anne L Hamilton, Sumitra Ananda, Marisa Grossi, Paul A Cohen, Yee C Leung, Robert M Rome, Philip J Beale, Penny Blomfield, Michael Friedlander, Alison Brand, Alexander Dobrovic, Martin Köbel, Paul Harnett, Brad H Nelson, David D L Bowtell, Anna DeFazio
PURPOSE: Women with epithelial ovarian cancer generally have a poor prognosis, however a subset of patients has an unexpected dramatic and durable response to treatment. We sought to identify clinical, pathological, and molecular determinants of exceptional survival in women with high-grade serous cancer (HGSC), a disease associated with the majority of ovarian cancer deaths. EXPERIMENTAL DESIGN: We evaluated the histories of 2,283 ovarian cancer patients and, after applying stringent clinical, and pathological selection criteria, identified 96 with HGSC that represented significant outliers in terms of treatment response and overall survival...
October 23, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29058290/mental-health-status-assessment-in-polycystic-ovarian-syndrome-infertility-patients-a-pilot-study
#20
Sai-Jiao Li, Dan-Ni Zhou, Wei Li, Jing Yang
Polycystic ovary syndrome (PCOS) is a major endocrine disorder afflicting women of reproductive age. Women with PCOS are more likely to suffer from mental health disturbances than healthy women. The "infertility" suffered by PCOS patients would also lead to mental health disturbances. Symptom Checklist 90 (SCL-90) and questionnaire which includes patients' socio-economic and demographic data were used to assess the mental health status of PCOS (n=103) and non-PCOS (n=110) infertile patients. Logistic regression analysis and t-tests were used for comparative analysis...
October 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
keyword
keyword
27957
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"