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https://www.readbyqxmd.com/read/29788453/myofascial-findings-and-psychopathological-factors-in-patients-with-chronic-pelvic-pain-syndrome
#1
Susanne G R Klotz, Gesche Ketels, Bernd Löwe, Christian A Brünahl
Objective: Chronic pelvic pain syndrome (CPPS) is a common pain condition with psychosocial and somatic symptoms. Myofascial findings and psychiatric comorbidities are frequent. Therefore, the aim of the study was to analyze myofascial and psychosocial aspects. Furthermore, the study focuses on correlations between these aspects and gender differences in this topic. Design: Cross-sectional study. Setting: Interdisciplinary outpatient clinic for patients with CPPS at the University Medical Centre Hamburg-Eppendorf, Germany...
May 19, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29785775/somatic-hematopoietic-tp53-mosaicism-in-women-with-breast-cancer-exposed-to-ionizing-radiation
#2
Sergey Melnov, Patricia Murphy, Thomas Foley, Eldar Nadyrov, Vyacheslav Kipen, Boris Leushev, Francesmary Modugno
No abstract text is available yet for this article.
May 21, 2018: Breast Journal
https://www.readbyqxmd.com/read/29785691/psychometric-properties-of-the-multidimensional-loss-scale-with-refugee-women-at-risk-recently-arrived-in-australia
#3
Lyn Vromans, Robert D Schweitzer, Mark Brough, Ignacio Correa-Velez, Kate Murray, Caroline Lenette
Refugee women-at-risk represent a distinct and vulnerable refugee population. We investigated the psychometric properties of the Multidimensional Loss Scale (MLS) with 104 women-at-risk, recently-arrived in Australia. Cross-sectional survey included: the MLS (indexing loss events and loss distress); Harvard Trauma Questionnaire (Indexing Trauma Events and Trauma Symptoms), and; Hopkins Symptom Checklist-37 (indexing anxiety, depression, and somatization symptoms). Exploratory factor analyses of MLS loss distress revealed a six-factor model (loss of symbolic self; loss of home; loss of interdependence; loss of past aspirations; interpersonal loss, and; loss of intrapersonal integrity)...
May 21, 2018: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/29784233/using-baseline-data-to-predict-chronic-ptsd-48-months-after-mothers-report-intimate-partner-violence-outcomes-for-mothers-and-the-intergenerational-impact-on-child-behavioral-functioning
#4
John Maddoux, Judith McFarlane, Lene Symes, Nina Fredland, Gene Feder
Worldwide one in three women report intimate partner violence. Many of these women report long term mental health problems, especially PTSD, which is associated with negative problem solving, isolation, somatization, depression, and anxiety. Children are impacted by their exposure to domestic violence and experience internal (i.e., depression, anxiety) and external (i.e., hostility, delinquency) behavioral clinical problems. To predict which women will experience chronic PTSD symptoms, a PTSD predictor tool was developed and applied to PTSD symptom scores four years after 300 mothers with children (age 18 months to 16 years) received assistance for the violence...
June 2018: Archives of Psychiatric Nursing
https://www.readbyqxmd.com/read/29781924/changes-in-psychiatric-and-medical-conditions-and-health-care-utilization-following-a-diagnosis-of-sexual-assault-a-retrospective-cohort-study
#5
Kelly C Young-Wolff, Varada Sarovar, Daniella Klebaner, Felicia Chi, Brigid McCaw
INTRODUCTION: Sexual assault (SA) is alarmingly common and is associated with higher prevalence of psychiatric and medical conditions. However, many prior studies are limited to cross-sectional designs. Health care systems with electronic health records provide unique longitudinal data to examine whether SA is associated with changes in health and health care utilization. METHODS: The sample included 1350 Kaiser Permanente Northern California adult female patients with a SA diagnosis from 2009 to 2015 and 4050 adult female patients without a SA diagnosis, matched on age, medical facility, and continuous enrollment during the study period...
May 17, 2018: Medical Care
https://www.readbyqxmd.com/read/29774227/identifying-what-matters-to-hysterectomy-patients-postsurgery-perceptions-beliefs-and-experiences
#6
Andrew S Bossick, Roopina Sangha, Heather Olden, Gwen L Alexander, Ganesa Wegienka
Purpose: Hysterectomy is the most common non-obstetrical surgery for women in the United States. Few investigations comparing hysterectomy surgical approaches include patient-centered outcomes. Methods: The study was performed at Henry Ford Health System in Detroit, Michigan between February 2015 and May 2015. The data were collected through structured focus groups with 24 post-hysterectomy women in order to identify PCOs to employ in a subsequent cohort study of hysterectomy surgical approaches...
2018: Journal of Patient-centered Research and Reviews
https://www.readbyqxmd.com/read/29767700/effects-of-iodized-salt-and-iodine-supplements-on-prenatal-and-postnatal-growth-a-systematic-review
#7
Jessica Farebrother, Celeste E Naude, Liesl Nicol, Zhongna Sang, Zhenyu Yang, Pieter L Jooste, Maria Andersson, Michael B Zimmermann
Hypothyroidism due to iodine deficiency can impair physical development, most visibly in the marked stunting of myxedematous cretinism caused by severe in utero iodine deficiency. Whether iodine repletion improves growth in noncretinous children is uncertain. Therefore, the aim of our systematic review was to assess the effects of iodine fortification or supplementation on prenatal and postnatal growth outcomes in noncretinous children. Following Cochrane methods and PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) reporting guidelines, we searched 10 databases including 2 Chinese databases (latest search February 2017)...
May 1, 2018: Advances in Nutrition
https://www.readbyqxmd.com/read/29756966/-may-pregestational-body-mass-index-be-related-to-mother-s-psychological-and-physical-condition-during-pregnancy
#8
Borja Romero-González, Rafael Arcangel Caparrós-González, Helen Strivens Vilchez, María Isabel Peralta-Ramírez
INTRODUCTION: pregestational Body Mass Index (BMI) affects mother's health during and after pregnancy and is related to negative outcomes such as low birth weight and preterm birth. Higher pregestational BMI may increase anxiety, stress and depression. OBJECTIVES: to assess potential differences on stress, psychopathological symptoms and physiological variables during pregnancy, among pregnant women with normal pregestational BMI rates and high pregestational BMI rates...
March 1, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29753961/the-role-of-parp-inhibition-in-triple-negative-breast-cancer-unraveling-the-wide-spectrum-of-synthetic-lethality
#9
REVIEW
Marios Papadimitriou, Giannis Mountzios, Christos A Papadimitriou
Triple-negative breast cancer (TNBC) accounts for approximately 15-20% of all breast cancers and is characterized by a lack of immunohistochemical expression of estrogen receptors (ER), progesterone receptors (PR) and HER2. TNBC is associated with poor long-term outcomes compared with other breast cancer subtypes. Many of these tumors are also basal-like cancers which are characterized by an aggressive biological behavior with a distant recurrence peak observed early at 3 years following diagnosis. Furthermore, metastatic TNBC bears a dismal prognosis with an average survival of 12 months...
May 2, 2018: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/29753010/determination-of-the-mutational-landscape-in-taiwanese-patients-with-papillary-thyroid-cancer-by-whole-exome-sequencing
#10
Chun-Chi Chang, Ya-Sian Chang, Hsi-Yuan Huang, Kun-Tu Yeh, Ta-Chih Liu, Jan-Gowth Chang
Among women in Taiwan, thyroid cancer is the fifth most common malignant neoplasia. However, genomic profiling of papillary thyroid cancer (PTC) cases from Taiwan has not been attempted previously. We used whole-exome sequencing to identify mutations in a cohort of 19 PTC patients. Sequencing was performed using the Illumina system; Sanger sequencing was used to validate all identified mutations. We identified new somatic mutations in APC, DICER1, LRRC8D and NDRG1. We also found somatic mutations in ARID5A, CREB3L2, MDM4, PPP2R5A and TFPT; mutations in these genes had been found previously in other tumors, but had not been described previously in PTC...
May 9, 2018: Human Pathology
https://www.readbyqxmd.com/read/29750367/efficacy-of-maternal-choline-supplementation-during-pregnancy-in-mitigating-adverse-effects-of-prenatal-alcohol-exposure-on-growth-and-cognitive-function-a-randomized-double-blind-placebo-controlled-clinical-trial
#11
Sandra W Jacobson, R Colin Carter, Christopher D Molteno, Mark E Stanton, Jane Herbert, Nadine M Lindinger, Catherine E Lewis, Neil C Dodge, H Eugene Hoyme, Steven H Zeisel, Ernesta M Meintjes, Christopher P Duggan, Joseph L Jacobson
BACKGROUND: We recently demonstrated the acceptability and feasibility of a randomized, double-blind choline supplementation intervention for heavy drinking women during pregnancy. In this paper, we report our results relating to the efficacy of this intervention in mitigating adverse effects of prenatal alcohol exposure on infant growth and cognitive function. METHODS: 69 Cape Coloured (mixed ancestry) heavy drinkers in Cape Town, South Africa, recruited in mid-pregnancy, were randomly assigned to receive a daily oral dose of either 2 g of choline or placebo from time of enrollment until delivery...
May 11, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29743982/effects-of-nordic-walking-on-oxidant-and-antioxidant-status-levels-of-calcidiol-and-proinflammatory-cytokines-in-middle-aged-women
#12
Wanda Pilch, Łukasz Tota, Anna Piotrowska, Ewa Śliwicka, Olga Czerwińska-Ledwig, Roxana Zuziak, Łucja Pilaczyńska-Szcześniak
Objectives: Nordic walking (NW) is relatively new and popular type of physical exercise with less studied effects than other sports activities. The aim of the study was to analyze possible changes in somatic indices, oxidant and antioxidant status, interleukins, and calcidiol levels in middle-aged women after a 12-week NW training program. Study Design: In this study, we examined the effects of NW training on selected measures and changes in body weight, fat mass, and calcidiol levels...
2018: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29743372/-breadth-and-functionality-of-varicella-zoster-virus-glycoprotein-specific-antibodies-identified-after-zostavax-vaccination-in-humans
#13
Nicole L Sullivan, Morgan A Reuter-Monslow, Janet Sei, Eberhard Durr, Carl W Davis, Cathy Chang, Megan McCausland, Andreas Wieland, David Krah, Nadine Rouphael, Aneesh K Mehta, Mark J Mulligan, Bali Pulendran, Rafi Ahmed, Kalpit A Vora
Herpes zoster (HZ/shingles) is the clinical manifestation of varicella zoster virus (VZV) reactivation. HZ typically develops as people age due to decreased cell-mediated immunity. However, the importance of antibodies for immunity against HZ prevention remains to be understood. The goal of this study was to examine the breadth and functionality of VZV-specific antibodies after vaccination with a live attenuated HZ vaccine (Zostavax). Direct enumeration of VZV-specific antibody secreting cells (ASC) via ELISPOT showed that Zostavax can induce both IgG and IgA ASCs seven days after vaccination, but not IgM ASCs...
May 9, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29731958/main-implications-related-to-the-switch-to-brca-1-2-tumor-testing-in-ovarian-cancer-patients-a-proposal-of-a-consensus
#14
Ettore Capoluongo, Giovanni Scambia, Jean-Marc Nabholtz
Background: Since the approval of the first poly (adenosine diphosphate [ADP]) ribose polymerase inhibitor (PARPi; olaparib [Lynparza™]) for platinum-sensitive relapsed high grade ovarian cancer, with either germline or somatic BRCA1/2 deleterious variants, the strategies for BRCA1/2 are dynamically changing. Along with germline testing within the context of familial or sporadic ovarian cancer, patients are now being referred for BRCA1/2 genetic assay above all for treatment decisions: in this setting tumour BRCA assay can allow to identify an estimated 3-9% of patients with peculiar somatic BRCA1/2 mutations...
April 13, 2018: Oncotarget
https://www.readbyqxmd.com/read/29728662/retinal-microcirculation-and-leukocyte-telomere-length-in-the-general-population
#15
Dries S Martens, Fang-Fei Wei, Bianca Cox, Michelle Plusquin, Lutgarde Thijs, Ellen Winckelmans, Zhen-Yu Zhang, Tim S Nawrot, Jan A Staessen
Retinal arteriolar narrowing increases with age and predict adverse cardiovascular outcomes. Telomere length keeps track of the division of somatic cells and is a biomarker of biological age. We investigated to what extent retinal arteriolar diameters are associated with biological age, as captured by leukocyte telomere length (LTL). In 168 randomly selected Flemish participants from the family-based population study FLEMENGHO (mean age, 46.2 years) at baseline, of whom 85 underwent a follow-up examination (median, 4...
May 4, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29726953/genetic-characterization-of-gnrh-lh-responsive-primary-aldosteronism
#16
Nadia Gagnon, Katia Caceres, Gilles Corbeil, Nada El Ghorayeb, Natasha Ludwig, Mathieu Latour, André Lacroix, Isabelle Bourdeau
Background: Recently, somatic beta-catenin mutations (CTNNB1) identified in aldosterone-producing adenomas (APA) from 3 women, were suggested to be responsible for the aberrant overexpression of LHCGR and GNRHR in the APA. Objective: To genetically characterize patients with primary aldosteronism (PA) evaluated in vivo for GnRH/LH responsive aldosterone secretion. Method: Patients with PA were evaluated in vivo to determine the possible regulation of aldosterone secretion by GnRH or LH...
May 2, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29720953/psychometric-properties-and-measurement-invariance-of-the-brief-symptom-inventory-18-among-chinese-insurance-employees
#17
Mingshu Li, Meng-Cheng Wang, Yiyun Shou, Chuxian Zhong, Fen Ren, Xintong Zhang, Wendeng Yang
This study aimed to examine the psychometric properties and factorial invariance of the Brief Symptom Inventory-18 (BSI-18). Confirmatory factor analyses (CFAs) were performed to verify the BSI-18's factor structure in a large sample of Chinese insurance professionals ( N = 2363, 62.7% women; age range = 19-70). Multigroup CFA were performed to test the measurement invariance of the model with the best fit across genders. In addition, structural equation modeling was conducted to test the correlations between the BSI-18 and two covariates - social support perception and grit trait...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29717286/quality-of-life-of-peri-and-postmenopausal-women-attending-outpatient-department-of-obstretics-and-gynecology-of-a-tertiary-care-hospital
#18
Sunita Koirala, Naresh Manandhar
BACKGROUND: Many women experience menopausal symptoms during menopausal transition and postmenopausal years. This natural phenomenon often results in various psychological, somatic and urinary symptoms which impair the overall quality of life of women. This study aimed to access the quality of life of women during perimenopausal and early postmenopausal years attending outpatient department of OBGYN at Kathmandu Medical College Teaching Hospital. METHODS: A descriptive cross-sectional study of 240 perimenopausal women of aged 45-60 years attending gynaecological outpatient clinic was carried out between 15th January to 13th April 2017...
March 13, 2018: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/29706306/psychiatric-comedication-in-patients-with-epilepsy
#19
Magdalena Bosak, Katarzyna Cyranka, Dominika Dudek, Monika Kowalik, Patrycja Mołek, Agnieszka Słowik
Psychiatric disorders are more common in patients with epilepsy than in the general population. The aims of the study were to assess the frequency and type of psychotropic drug usage in patients with epilepsy, to assess the risk factors for their use, and to assess their proconvulsive potential and the risk of interactions with antiepileptic drugs. This 20-month prospective study included patients treated at the university hospital outpatient clinic. Psychotropic drugs have been classified according to the Anatomical Therapeutic Chemical Classification System...
April 26, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29700350/mindfulness-based-stress-reduction-mbsr-or-psychoeducation-for-the-reduction-of-menopausal-symptoms-a-randomized-controlled-clinical-trial
#20
Carmen Wong, Benjamin Hon-Kei Yip, Ting Gao, Kitty Yu Yuk Lam, Doris Mei Sum Woo, Annie Lai King Yip, Chloe Yu Chin, Winnie Pui Yin Tang, Mandy Mun Tse Choy, Katrina Wai Key Tsang, Suzanne C Ho, Helen Shuk Wah Ma, Samuel Yeung Shan Wong
Psychological and behavioural interventions may be effective in reducing menopause-related symptoms. This randomized controlled trial aimed to evaluate the effectiveness of Mindfulness-based Stress Reduction (MBSR) in reducing menopause-related symptoms by comparing with an active control group, the menopause education control (MEC). Symptomatic peri-menopausal and post-menopausal women with mild to moderate symptoms were recruited. The primary outcome was overall menopausal symptoms measured by modified Greene Climacteric Scale (GCS)...
April 26, 2018: Scientific Reports
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