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https://www.readbyqxmd.com/read/28217611/pyoderma-gangrenosum-a-clinician-s-nightmare
#1
Bindhu Bhaskaran, Mittu John Mathew, K N Vijayan, Asha Zacharia
Pyoderma gangrenosum (PG) is a rare disease and that affecting specifically the sole of the foot, is even rarer. Here, we report the case of a 54-year-old female admitted with a painful ulcer on the sole of the right foot which was initially treated with empirical antibiotics and debridement. The disease was found to spread rapidly after each debridement. The culture reports were negative; rheumatology workup and Doppler study were within normal limits. A clinical suspicion of PG was made and was confirmed with tissue biopsy...
July 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/28217061/sequestrated-caudal-catheter-in-a-child-an-anesthetic-nightmare-and-surgical-dilemma
#2
Chong Soon Eu, Shyamala V Kumar, Saedah Ali, Shamsul Kamalrujan Hassan
The usage of epidural infusion for intraoperative and postoperative pain relief is widely used in certain pediatric anesthetic practice because of the effectiveness and advantages. However, there is drawback for these techniques due to its potential complications such as inadvertent intrathecal placement, local anesthetic toxicity, catheter migration, infection, and breakage of epidural catheter. Though occur infrequently, epidural catheters have been known to snap during insertion or removal. The retained catheter tip may lead to multiple complications, including nerve injury, infection, and even catheter migration...
January 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/28215231/use-of-varenicline-in-smokeless-tobacco-cessation-influences-sleep-quality-and-dream-recall-frequency-but-not-dream-affect
#3
Francesca Polini, Rosastella Principe, Serena Scarpelli, Francesca Clementi, Luigi De Gennaro
OBJECTIVE: Varenicline (VCL) treatment has become popular as a part of smoking-cessation therapies, even though its possible implications in neuropsychiatric adverse events include abnormal sleep and nightmares. Our study is the first aimed at prospectively investigating changes in sleep and dream measures across such treatment by using a one week sleep diary and collecting dream recall (DR). METHODS: Thirty-eight smokers participated in two different effective smoking-cessation programs: 25 subjects received VCL, 13 subjects received nicotine replacement therapy (NRT)...
February 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28141722/sudden-onset-of-refusal-to-eat-on-waking-after-a-nightmare-in-a-6-year-old-girl
#4
Maria Zaccagnino, Sheila Gahagan, Andrea Spencer, Michael Jellinek, Martin T Stein
Bridgette is a 6-year-old girl, who presented with sudden onset of refusal to eat or drink. The only precipitating event was a nightmare the previous night. She described a dream in which her mother and maternal aunt, dressed as witches, and father and maternal uncle, appearing as bats, wanted to kill her by making her eat and drink from a cauldron. Bridgette stated, "I can't eat anymore, I'm afraid of dying." Bridgette's eating pattern and behavior were described as previously normal. Motor, social, and language milestones were also normal...
February 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28141717/behavioral-changes-associated-with-a-disruptive-new-student-in-the-classroom
#5
Julie Stein OʼBrien, Howard Taras, Scott Barton, Pete Sellick, Martin T Stein
Marcus is a 10-year-old boy who was followed by his pediatrician for several years. She knows him as a socially engaged, active athlete, playing soccer and baseball, out-going, and a good student. He has been in good health without a significant medical history.At the beginning of this academic year, a new student was placed in Marcus's fourth grade class. This student is disruptive, impulsive, and abusive. He has frequent violent outbursts, yelling, kicking, and throwing objects, including recently throwing a desk across the room...
February 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28131947/cumulative-childhood-maltreatment-and-its-dose-response-relation-with-adult-symptomatology-findings-in-a-sample-of-adult-survivors-of-sexual-abuse
#6
Iris M Steine, Dagfinn Winje, John H Krystal, Bjørn Bjorvatn, Anne Marita Milde, Janne Grønli, Inger Hilde Nordhus, Ståle Pallesen
In the present study, we examined the role of cumulative childhood maltreatment experiences for several health related outcomes in adulthood, including symptoms of psychological distress as well as perceived social support and hardiness. The sample comprised adult survivors of sexual abuse (N=278, 95.3% women, mean age at first abusive incident=6.4 years). One-way ANOVAs revealed a statistically significant dose-response relation between cumulative childhood maltreatment scores and self-reported symptoms of posttraumatic stress (PTSS), anxiety, depression, eating disorders, dissociation, insomnia, nightmare related distress, physical pain, emotional pain, relational problems, self-harm behaviors as well as on a measure of symptom complexity...
January 26, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28129305/positive-association-between-nightmares-and-heart-rate-response-to-loud-tones-relationship-to-parasympathetic-dysfunction-in-ptsd-nightmares
#7
Kaloyan S Tanev, Scott P Orr, Edward F Pace-Schott, Michael Griffin, Roger K Pitman, Patricia A Resick
Seventy-three women with posttraumatic stress disorder (PTSD) resulting from rape or physical assault participated in a loud-tone procedure, while skin conductance (SC), heart rate, and electromyogram responses were recorded. Pearson correlations were examined between each psychophysiological response and Clinician-Administered PTSD Scale (CAPS) symptom scores. Significant correlations were adjusted for each remaining individual PTSD symptom score. Heart rate response (HRR) significantly correlated with CAPS total score and with CAPS nightmares...
January 26, 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/28121084/melanoma-clinical-and-dermoscopic-diagnosis
#8
Gabriella Brancaccio, Teresa Russo, Aimilios Lallas, Elvira Moscarella, Marina Agozzino, Giuseppe Argenziano
Missing the diagnosis of a melanoma is the worst dermatologist nightmare, especially when melanomas have a non-alarming clinical appearance and imitate a completely benign lesion. The use of dermoscopy has provided an effective tool to facilitate the differential diagnosis and to increasingly allow an early diagnosis of melanoma. The aim of this article is to summarize the most recent and important clinical and dermoscopic pearls to recognize melanoma at the earliest stages of its development.
January 24, 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/28119861/intestinal-perforation-a-surgeon-s-nightmare-enlightened-by-scientific-research
#9
EDITORIAL
Byung Soh Min
No abstract text is available yet for this article.
December 2016: Annals of Coloproctology
https://www.readbyqxmd.com/read/28110799/estimated-prevalence-of-insomnia-among-women-veterans-results-of-a-postal-survey
#10
Jennifer L Martin, C Amanda Schweizer, Jaime M Hughes, Constance H Fung, Joseph M Dzierzewski, Donna L Washington, B Josea Kramer, Stella Jouldjian, Michael N Mitchell, Karen R Josephson, Cathy A Alessi
OBJECTIVES: Insomnia is a significant public health concern known to particularly impact women and the veteran population; however, rates of insomnia disorder among women veterans are not known. METHOD: Women veterans who had received health care at VA Greater Los Angeles Healthcare System between 2008 and 2010 and resided within 25 miles of the facility were sent a postal survey assessing sleep, demographics, and other related patient characteristics. RESULTS: A total of 660 women (43...
January 17, 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/28110112/verbal-memory-functioning-moderates-psychotherapy-treatment-response-for-ptsd-related-nightmares
#11
J Cobb Scott, Gerlinde Harb, Janeese A Brownlow, Jennifer Greene, Ruben C Gur, Richard J Ross
Posttraumatic stress disorder (PTSD) is associated with cognitive deficits in attention, executive control, and memory, although few studies have investigated the relevance of cognitive difficulties for treatment outcomes. We examined whether cognitive functioning and history of traumatic brain injury (TBI) were associated with response to cognitive-behavioral therapy (CBT) for PTSD-related sleep problems. In a randomized controlled trial of Imagery Rehearsal (IR) added to components of CBT for Insomnia (IR + cCBT-I) compared to cCBT-I alone for PTSD-related recurrent nightmares, 94 U...
January 13, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28106623/symptom-presentation-and-prescription-of-sleep-medications-for-veterans-with-posttraumatic-stress-disorder
#12
Mark A Greenbaum, Thomas C Neylan, Craig S Rosen
This study tested whether sleep medications prescribed to veterans diagnosed with posttraumatic stress disorder (PTSD) are being targeted to patients who report more severe insomnia or nightmares. Secondary analysis of survey and pharmacy data was conducted in samples of veterans from two periods: from 2006 to 2008 and from 2009 to 2013. Logistic regression tested associations between self-reported insomnia and nightmare severity, and being prescribed trazodone, prazosin, zolpidem, and benzodiazepines, controlling for PTSD severity and other covariates...
February 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/28096705/situational-judgment-tests-reliably-measure-professional-attributes-important-for-clinical-practice
#13
EDITORIAL
Katie Petty-Saphon, Kim A Walker, Fiona Patterson, Vicki Ashworth, Helena Edwards
Over the course of more than 40 years, international research has consistently shown situational judgment tests (SJTs) to be a reliable and valid selection method for assessing a range of professional attributes. However, SJTs still represent a relatively new selection method within the medical profession, and as such it is to be expected that applicant reactions will vary. In this Expert Opinion piece, we respond to Najim et al's article "The situational judgement test: a student's worst nightmare" by highlighting three key clarifications...
2017: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/28067693/intraoperative-ketamine-reduces-immediate-postoperative-opioid-consumption-after-spinal-fusion-surgery-in-chronic-pain-patients-with-opioid-dependency-a-randomized-blinded-trial
#14
Rikke Vibeke Nielsen, Jonna Storm Fomsgaard, Hanna Siegel, Robertas Martusevicius, Lone Nikolajsen, Jørgen Berg Dahl, Ole Mathiesen
Perioperative handling of surgical patients with opioid dependency represents an important clinical problem. Animal studies suggest that ketamine attenuates central sensitization and hyperalgesia and thereby reduces postoperative opioid tolerance. We hypothesized that intraoperative ketamine would reduce immediate postoperative opioid consumption compared with placebo in chronic pain patients with opioid dependency undergoing lumbar spinal fusion surgery. Primary outcome was morphine consumption 0 to 24 hours postoperatively...
March 2017: Pain
https://www.readbyqxmd.com/read/28063723/early-illness-experiences-related-to-unexpected-heart-surgery-a-qualitative-descriptive-study
#15
Yu-Ling Chang, Yun-Fang Tsai
BACKGROUND: Most studies on patients' experiences following emergency cardiac surgery focus on evaluation of patients after their discharge. Few studies have evaluated patients' experiences after being transferred from intensive care and before being discharged. OBJECTIVE: This study aimed to describe patients' experiences in the early stages of recovery following emergency heart surgery. METHODS: For this exploratory qualitative descriptive study, 13 patients were recruited from a medical centre in northern Taiwan...
January 4, 2017: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/28049901/improvement-of-clinical-skills-through-pharmaceutical-education-and-clinical-research
#16
Junko Ishizaki
 Professors and teaching staff in the field of pharmaceutical sciences should devote themselves to staying abreast of relevant education and research. Similarly those in clinical pharmacies should contribute to the advancement of pharmaceutical research and the development of next generation pharmacists and pharmaceuticals. It is thought that those who work in clinical pharmacies should improve their own skills and expertise in problem-finding and -solving, i.e., "clinical skills". They should be keen to learn new standard treatments based on the latest drug information, and should try to be in a position where collecting clinical information is readily possible...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28043500/design-and-development-of-novel-inhibitors-for-the-treatment-of-latent-tuberculosis
#17
Rudraraju Srilakshmi Reshma, Perumal Yogeeswari, Dharmarajan Sriram
OBJECTIVE/BACKGROUND: "The captain of all these men of death", is the apt sobriquet for the age-old disease tuberculosis (TB). Despite the availability of many drugs, cases of increasing resistance in the forms of multi-drug and extensively drug-resistant TB and persistence [characteristic of Mycobacterium tuberculosis (MTB)] make the eradication of TB a nightmare. Approval of bedaquiline by the Food and Drug Administration focused attention on quinoline scaffolds for development of new anti-TB agents...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28012195/angels
#18
Blair P Grubb
No abstract text is available yet for this article.
December 24, 2016: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28003700/-can-t-ventilate-during-surgery-nightmare-for-anaesthesiologist
#19
Preety Mittal Roy, Sangeeta Khanna, Yatin Mehta, A Z Khan
No abstract text is available yet for this article.
December 2016: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28002832/acute-and-chronic-posttraumatic-stress-symptoms-in-the-emergence-of-posttraumatic-stress-disorder-a-network-analysis
#20
Richard A Bryant, Mark Creamer, Meaghan O'Donnell, David Forbes, Alexander C McFarlane, Derrick Silove, Dusan Hadzi-Pavlovic
Importance: Little is understood about how the symptoms of posttraumatic stress develop over time into the syndrome of posttraumatic stress disorder (PTSD). Objective: To use a network analysis approach to identify the nature of the association between PTSD symptoms in the acute phase after trauma and the chronic phase. Design, Setting, and Participants: A prospective cohort study enrolled 1138 patients recently admitted with traumatic injury to 1 of 4 major trauma hospitals across Australia from March 13, 2004, to February 26, 2006...
February 1, 2017: JAMA Psychiatry
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