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oral sensation testing

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https://www.readbyqxmd.com/read/29928871/experimental-tooth-movement-temporally-changes-neural-excitation-and-topographical-map-in-rat-somatosensory-cortex
#1
Mari Kaneko, Satoshi Fujita, Noriyoshi Shimizu, Mitsuru Motoyoshi, Masayuki Kobayashi
During orthodontic treatment, binding teeth, may change the topographically organized representation of teeth in the cerebral cortex. To test the hypothesis that experimental tooth movement (ETM) changes the somatotopy of an individual tooth arrangement in the somatosensory cortex, we examined the spatiotemporal features of cortical excitatory propagation in response to mechanical stimulation of the maxillary incisor or molar using optical imaging in late adolescent rats without or with ETM. The ETM models consisted of 1d, 3d, and 7d ETM in which a closed-coil spring was ligated between the maxillary first molar and incisors...
June 18, 2018: Brain Research
https://www.readbyqxmd.com/read/29911032/assessment-and-evaluation-of-gustatory-functions-in-patients-with-diabetes-mellitus-type-ii-a-study
#2
Shriya Khera, Anjali Saigal
Introduction: The assessment of taste is critically important for an individual to enjoy life. This however, gets altered in various diseases. Diabetes Mellitus is one of the diseases in which person has dysgeusia. Objectives: This study was done to assess different taste sensations in patients suffering from Diabetes Mellitus Type II. Methods: A total of 120 subjects were taken in this study and were divided into 3 groups. One group consisted of patients who were uncontrolled diabetics ( n = 40), the second group of controlled diabetics ( n = 40) and 40 subjects who were normal healthy individuals (control group)...
March 2018: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29847962/xerostomia-salivary-gland-hypofunction-diagnosis-and-management
#3
Susan L Zunt
The patient with xerostomia (sensation of dry mouth) or inadequate saliva (salivary gland hypofunction) may present with a wide range of clinical signs and symptoms affecting the oral cavity and systemic health. Recognition of these clinical presentations allows the dental healthcare professional to perform objective tests to identify the status of salivary gland function. Based on these results, recommendations for treatment using over-the-counter and prescription medications can be made. This article discusses clinical indications related to salivary gland hypofunction, testing methodologies, and treatment approaches...
June 2018: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/29751045/detection-and-modulation-of-capsaicin-perception-in-the-human-oral-cavity
#4
Gregory Smutzer, Jeswin C Jacob, Joseph T Tran, Darshan I Shah, Shilpa Gambhir, Roni K Devassy, Eric B Tran, Brian T Hoang, Joseph F McCune
Capsaicin causes a burning or spicy sensation when this vanilloid compound comes in contact with trigeminal neurons of the tongue. This compound has low solubility in water, which presents difficulties in examining the psychophysical properties of capsaicin by standard aqueous chemosensory tests. This report describes a new approach that utilizes edible strips for delivering precise amounts of capsaicin to the human oral cavity for examining threshold and suprathreshold amounts of this irritant. When incorporated into pullulan-based edible strips, recognition thresholds for capsaicin occurred over a narrow range, with a mean value near 1 nmol...
May 8, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29744194/measurement-reliability-of-current-perception-threshold-and-pain-threshold-in-parallel-with-blood-sampling
#5
Takahiro Ogawa, Suguru Kimoto, Yoshio Nakashima, Nobuhiko Furuse, Masanori Ono, So Furokawa, Masakazu Okubo, Takahiro Yazaki, Yasuhiko Kawai
The irritation and pain associated with oral blood sampling necessary to monitor glycemic control can alter oral sensation, but no studies have measured the reliability of oral sensation testing when performed concurrently with blood sampling. The primary and secondary aims of this study were to verify the measurement reliability of current perception threshold (CPT) and pain threshold (PT) tests performed before and after blood sampling and to investigate the differences in CPTs/PTs obtained from the oral cavity, hand, and foot, respectively...
August 2017: Clinical and Experimental Dental Research
https://www.readbyqxmd.com/read/29673543/dihydrocapsiate-supplementation-prevented-high-fat-diet-induced-adiposity-hepatic-steatosis-glucose-intolerance-and-gut-morphological-alterations-in-mice
#6
Ritesh K Baboota, Pragyanshu Khare, Priyanka Mangal, Dhirendra Pratap Singh, Kamlesh K Bhutani, Kanthi K Kondepudi, Jaspreet Kaur, Mahendra Bishnoi
Despite the lipolytic and thermogenic properties of capsaicin, its putative use as a weight-lowering dietary supplement has been limited because of the burning sensation caused by capsaicin when it comes in contact with mucous membranes. A potential alternative to capsaicin are the capsinoids, nonpungent capsaicin analogs that exhibit effects similar to capsaicin. Whereas the antiobesity properties of capsinoids have been reported, the effectiveness of FDA-approved synthetic dihydrocapsiate has not yet been investigated...
March 2018: Nutrition Research
https://www.readbyqxmd.com/read/29624459/-introducing-modified-dakkak-and-bennett-grading-system-for-indian-food-in-oral-submucous-fibrosis-a-dharwad-study
#7
Chaithra Kalkur, Atul P Sattur, Kruthika S Guttal, Anusha R Lakshman
Oral submucous fibrosis (OSMF) is one of the "diseases of civilization" because of the large differences in prevalence among races, geographic areas, and individuals at different socioeconomic levels. It is a premalignant condition strongly associated with the habit of chewing areca nuts. This study is to compare the scoring system in relation to the burning sensation of mouth and dysphagia using the visual analog scale (VAS) and Dakkak and Bennett grading system for Indian food, respectively, in OSMF patients...
April 6, 2018: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29520791/self-perceived-oral-symptoms-and-periodontal-status-among-young-intravenous-heroin-addicts-a-cross-sectional-case-control-study
#8
Abid Mehmood, Tariq Abduljabbar, Nawwaf Al-Hamoudi, Elham Gholamiazizi, Sergio Varela Kellesarian, Fahim Vohra, Fawad Javed
BACKGROUND: It is hypothesized that (a) self-perceived oral symptoms (OSs) are worse in intravenous heroin addicts (IHA) than controls; and (b) clinical periodontal inflammatory parameters (plaque index [PI], bleeding on probing [BOP], PD and clinical attachment loss [AL]), number of missing teeth (MT) and radiographic marginal bone loss (MBL) are higher in IHA compared with controls. The aim was to compare the self-perceived OSs and periodontal parameters among young IHA and controls...
February 19, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/29510851/comparison-of-the-effects-of-curcumin-mucoadhesive-paste-and-local-corticosteroid-on-the-treatment-of-erosive-oral-lichen-planus-lesions
#9
Tahereh Nosratzehi, Fateme Arbabi-Kalati, Hamed Hamishehkar, Sudabeh Bagheri
INTRODUCTION: Lichen planus is a prevalent chronic mucocutaneous condition, whose exact pathogenesis has not been elucidated yet and its standard treatment at present involves the use of local corticosteroids. Curcumin is a colored material extracted from Curcuma longa plant species and is used as an appetizer and for medical purposes. It has anti-inflammatory, antioxidative and anti-cancerous properties. In the present study, the effect of mucoadhesive pastes containing curcumin and local corticosteroids was evaluated for the treatment of erosive lichen planus lesions...
February 2018: Journal of the National Medical Association
https://www.readbyqxmd.com/read/29507908/understanding-of-burning-mouth-syndrome-based-on-psychological-aspects
#10
Moon-Jong Kim, Hong-Seop Kho
Burning mouth syndrome (BMS) is a chronic pain condition characterised by a persistent burning sensation in clinically normal oral mucosa. BMS most commonly occurs in middleaged and elderly women. Various local and systemic factors can cause oral burning symptoms. When all possible local and systemic factors are excluded, burning mouth symptoms can be diagnosed as BMS. Psychophysical tests and histopathological data suggest the involvement of peripheral and central neuropathic mechanisms in BMS etiopathogenesis...
2018: Chinese Journal of Dental Research
https://www.readbyqxmd.com/read/29492414/comparison-the-pain-relief-of-amitriptyline-mouthwash-with-benzydamine-in-oral-mucositis
#11
Shahla Kakoei, Abbas Pardakhty, Maryam-Al-Sadat Hashemipour, Hasan Larizadeh, Behjat Kalantari, Elaheh Tahmasebi
Statement of the Problem: A significant proportion of patients undergoing chemotherapy or radiotherapy suffer from mucositis. The first symptom of oral mucositis is pain. Severe pain, burning sensation, and discomfort in the oral cavity make it difficult to continue treatment and even continue living in these patients. Purpose: The aim of this study was to evaluate and compare the effect of amitriptyline mouthwash (in two forms of simple and niosomal) as a local anesthetic agent with benzydamine HCl mouthwash in oral mucositis after radiotherapy or chemotherapy...
March 2018: Journal of Dentistry
https://www.readbyqxmd.com/read/29490289/maintaining-physiologic-testosterone-levels-during-combined-oral-contraceptives-by-adding-dehydroepiandrosterone-ii-effects-on-sexual-function-a-phase-ii-randomized-double-blind-placebo-controlled-study
#12
Rik H W van Lunsen, Yvette Zimmerman, Herjan J T Coelingh Bennink, Hanneke M M Termeer, Nicole Appels, Bart C J M Fauser, Ellen Laan
OBJECTIVE: The objective was to evaluate the effect of combined oral contraceptives (OCs) on sexual function, either alone or together with dehydroepiandrosterone (DHEA). STUDY DESIGN: An exploratory randomized, double-blind, placebo-controlled, comparative, crossover study was conducted in 81 OC users. Subjects discontinued their OC for one cycle before being randomized for 10cycles to a 30-mcg ethinyl estradiol (EE)/levonorgestrel (LNG) OC or a 30-mcg EE/drospirenone (DRSP) OC, along with daily use of 50mg dehydroepiandrosterone (DHEA) or placebo during five OC cycles before crossing over from DHEA to placebo or the reverse for another fivecycles...
February 25, 2018: Contraception
https://www.readbyqxmd.com/read/29380039/olfactory-and-gustatory-functions-after-free-flap-reconstruction-and-radiotherapy-for-oral-and-pharyngeal-cancer-a-prospective-follow-up-study
#13
Markus Lilja, Mari Markkanen-Leppänen, Sanna Viitasalo, Kauko Saarilahti, Andrew Lindford, Patrik Lassus, Antti Mäkitie
BACKGROUND: The senses of smell and taste can be adversely affected by both tumour- and treatment-related factors amongst head and neck cancer patients. The consequences may negatively impact nutritional status as well as quality of life in this patient population. PATIENTS AND METHODS: This prospective longitudinal follow-up study is consisted of 44 patients treated for oral cavity, oropharyngeal or hypopharyngeal cancer with tumour resection and microvascular free tissue transfer reconstruction at the Helsinki University Hospital, Helsinki, Finland...
April 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29284179/differences-in-pain-thresholds-elicited-by-intraoral-electrical-stimuli-between-individuals-with-and-without-diabetes-mellitus
#14
T Ogawa, S Kimoto, Y Nakashima, N Furuse, M Ono, S Furokawa, M Okubo, H Yamaguchi, Y Kawai
There is little evidence of sensation in individuals with diabetes mellitus (DM) in the dental research field. We investigated whether pain thresholds (PTs) differ between individuals with and without DM (non-DM; NDM). To this end, we assessed whether PTs obtained from the oral cavity, hands, and feet differed from each other and across groups, and whether PTs differed for the three current frequencies used for testing (2000 Hz, 250 Hz, and 5 Hz). Pain threshold measurements were obtained from the oral mucosa and the tips of the fingers and toes of 56 volunteers, including 21 individuals with DM (12 men and 9 women, average age: 72...
March 2018: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29258592/possible-therapeutic-effect-of-orally-administered-ribavirin-for-respiratory-syncytial-virus-induced-acute-respiratory-distress-syndrome-in-an-immunocompetent-patient-a-case-report
#15
Byung Woo Yoon, Seung Hyeun Lee
BACKGROUND: Human respiratory syncytial virus usually causes self-limiting upper respiratory infection and occasionally causes pneumonia in immunocompromised hosts. Respiratory syncytial virus-induced severe pneumonia or acute respiratory distress syndrome in immunocompetent adults has been rarely described. Unfortunately, optimal treatment has not been established for this potentially fatal condition. We report a case of respiratory syncytial virus-induced acute respiratory distress syndrome occurring in a previously healthy man successfully treated with orally administered ribavirin...
December 20, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29094055/effect-of-menstrual-cycle-on-acute-intermittent-porphyria
#16
V R Souza Júnior, V M V Lemos, I M L Feitosa, R Florencio, C W B Correia, L B Correia Fontes, M F Hazin Costa, M C B Correia
A 16-year-old female who was attended as an outpatient reported localized, acute abdominal pain with vomiting, symmetrical motor weakness, and burning sensation in both arms and legs. Her medical history showed irrational behavior, repeated admissions at the emergency units of many other reference hospitals, where she had been investigated for celiac disease and treated with analgesics for pain events. Her clinical condition remained unchanged despite the use of many oral analgesics. In those admissions, she showed dysautonomia, vomiting, and abdominal pain...
January 2017: Child Neurology Open
https://www.readbyqxmd.com/read/29024230/%C3%AE-aminobutyric-acid-gaba-oral-rinse-reduces-capsaicin-induced-burning-mouth-pain-sensation-an-experimental-quantitative-sensory-testing-study-in-healthy-subjects
#17
Y Zhang, K Wang, L Arendt-Nielsen, B E Cairns
BACKGROUND: In burning mouth patients, analgesia after oral administration of clonazepam may result from modulation of peripheral γ-aminobutyric acid (GABA) receptors. METHODS: The effect of oral administration of test solutions (water, 0.5 mol/L or 0.05 mol/L GABA, 1% lidocaine) was investigated for the amelioration of pain and sensitivity induced by application of capsaicin (1%, 2 min) to the tongue of thirty healthy male and female subjects in this four-session, randomized, placebo-controlled, double-blinded, cross-over study...
February 2018: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28967406/effects-of-mouth-rehabilitation-with-removable-complete-dentures-on-stimulus-perception-and-the-electromyographic-activity-of-the-orbicularis-oris-muscle
#18
Fernanda P de Caxias, Daniela M Dos Santos, Marcelo C Goiato, Sandro B Bitencourt, Emily V F da Silva, Murilo C B Laurindo-Junior, Karina H L Turcio
STATEMENT OF PROBLEM: Many elderly individuals are rehabilitated with removable complete dentures, which require an initial adaptation period for both oral perception and the perioral muscles. Studies assessing the changes in stimulus perception and the electromyographic (EMG) activity of the orbicularis oris muscle shortly after conventional complete denture insertion are lacking. PURPOSE: The purpose of this clinical study was to evaluate the effect of mouth rehabilitation with removable complete dentures on stimulus perception and the EMG activity of the orbicularis oris muscle...
September 26, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28967223/human-capability-in-the-perception-of-extensional-and-shear-viscosity
#19
Zhihong Lv, Jianshe Chen, Melvin Holmes
Shear and extensional deformation are two basic rheological phenomena which occur commonly in our daily life. Because of the very different nature of the two deformations, fluid materials may exhibit significant differences in their responses to shear and extensional forces. This work investigated the human perception of shear and extensional viscosity and tested the hypothesis that human have different discriminatory sensation mechanisms including scaling to the two deformations. A series of fluid samples were prepared using two common food thickeners, guar gum and sodium carboxylmethylcellulose (CMC-Na)...
October 2017: Journal of Texture Studies
https://www.readbyqxmd.com/read/28895150/chemosensory-function-before-and-after-multimodal-treatment-in-chronic-rhinosinusitis-patients
#20
Ute Walliczek-Dworschak, Robert Pellegrino, Franziska Taube, Christian A Mueller, Boris Alexander Stuck, Philipp Dworschak, Christian Güldner, Silke Steinbach
OBJECTIVES/HYPOTHESIS: Olfactory dysfunction is common among the general population, with chronic rhinosinusitis (CRS) as one of the leading causes. Patients affected by CRS often report changes in taste sensations; however, quantitative measurements have not been performed to date. Therefore, the present study aimed to investigate gustatory and olfactory function in CRS patients prior to and after multimodal treatment. STUDY DESIGN: Prospective cohort study. METHODS: Twenty-one patients suffering from CRS with nasal polyps (14 male, seven female) with a mean age of 48 ± 15 years were included in the study...
March 2018: Laryngoscope
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