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https://www.readbyqxmd.com/read/29336237/masticatory-function-and-oral-stereognosis-in-bruxers
#1
Mariana Barbosa Câmara-Souza, Olívia Maria Costa Figueredo, Renata Cunha Matheus Rodrigues Garcia
OBJECTIVE: To compare the mastication and oral sensory function of individuals with and without sleep bruxism. METHODS: The sample comprised 60 volunteers, of which 30 were bruxers (mean age = 30.5 ± 6.0) and 30 non-bruxers (mean age = 28.6 ± 3.3). Sleep bruxism was clinically diagnosed and confirmed using the Bruxoff® device. Mastication was evaluated according to swallowing threshold and masticatory efficiency. Swallowing threshold was determined from the median particle size of Optosil®, obtained after an individualized number of masticatory cycles, which was first determined by chewing peanuts; masticatory efficiency was estimated by the sieving method...
January 16, 2018: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/29298327/gabaergic-mechanisms-involved-in-the-prepulse-inhibition-of-auditory-evoked-cortical-responses-in-humans
#2
Koji Inui, Nobuyuki Takeuchi, Shunsuke Sugiyama, Eishi Motomura, Makoto Nishihara
Despite their essential roles in signal processing in the brain, the functions of interneurons currently remain unclear in humans. We recently developed a method using the prepulse inhibition of sensory evoked cortical responses for functional measurements of interneurons. When a sensory feature is abruptly changed in a continuous sensory stimulus, change-related cortical responses are recorded using MEG. By inserting a weak change stimulus (prepulse) before the test change stimulus, it is possible to observe the inhibition of the test response...
2018: PloS One
https://www.readbyqxmd.com/read/29280136/the-influence-of-tongue-strength-on-oral-viscosity-discrimination-acuity
#3
Catriona M Steele
The influence of tongue strength on oral viscosity discrimination acuity The ability to generate tongue pressures is widely considered to be critical for liquid bolus propulsion in swallowing. It has been proposed that the application of tongue pressure may also serve the function of collecting sensory information regarding bolus viscosity (resistance to flow). In this study, we explored the impact of age-related reductions in tongue strength on oral viscosity discrimination acuity. The experiment employed a triangle test discrimination protocol with an array of xanthan-gum thickened liquids in the mildly- to moderately-thick consistency range...
December 27, 2017: Journal of Texture Studies
https://www.readbyqxmd.com/read/29240979/brief-exposures-to-the-taste-of-ethanol-and-quinine-promote-subsequent-acceptance-of-ethanol-in-a-paradigm-that-minimizes-post-ingestive-consequences
#4
Gregory C Loney, Paul J Meyer
BACKGROUND: Aversion to the orosensory properties of concentrated ethanol solutions is often cited as a primary barrier to initiation of drinking and may contribute to abstention. These aversive properties include gustatory processes which encompass both bitter-like taste qualities and trigeminal-mediated irritation. Chronic-intermittent ethanol access (CIA) results in substantial and persistent increases in ethanol consumption, but the degree to which this facilitation involves sensory responding to ethanol and other bitter stimuli is currently undetermined...
December 14, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29182947/low-level-neural-auditory-discrimination-dysfunctions-in-specific-language-impairment-a-review-on-mismatch-negativity-findings
#5
REVIEW
Teija Kujala, Miika Leminen
In specific language impairment (SLI), there is a delay in the child's oral language skills when compared with nonverbal cognitive abilities. The problems typically relate to phonological and morphological processing and word learning. This article reviews studies which have used mismatch negativity (MMN) in investigating low-level neural auditory dysfunctions in this disorder. With MMN, it is possible to tap the accuracy of neural sound discrimination and sensory memory functions. These studies have found smaller response amplitudes and longer latencies for speech and non-speech sound changes in children with SLI than in typically developing children, suggesting impaired and slow auditory discrimination in SLI...
October 24, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29130554/sensory-recovery-of-myomucosal-flap-oral-cavity-reconstructions
#6
Olindo Massarelli, Luigi Angelo Vaira, Andrea Biglio, Roberta Gobbi, Giovanni Dell'aversana Orabona, Giacomo De Riu
BACKGROUND: Sensory restoration of the oral cavity is a primary aim of reconstructive surgery in posttraumatic or postablative defects. Sensitivity plays a key role in oral function, whose impairment strongly affects the patient's quality of life. Cheek myomucosal flaps provide a reliable and tissue-like reconstruction of these regions but their sensitive recovery, which we still know little about, deserves thorough assessment. METHODS: In this retrospective study, the myomucosal cheek flaps were tested for different aspects of sensory recovery: touch; 2-point discrimination; pain; sharp/smooth discrimination; ability to feel hot/cold stimulus; stereognosis; and taste...
November 11, 2017: Head & Neck
https://www.readbyqxmd.com/read/29064764/evaluation-of-oral-stereognosis-in-relation-to-tactile-ability-and-patient-satisfaction
#7
Ikbal Leblebicioglu Kurtulus, Kerem Kilic, Ravza Eraslan, Damla Unlu, Ahmet Caliskan, Bulent Kesim, Stephan Eitner
We investigated the oral stereognostic ability of dentate individuals, conventional complete denture patients, and maxillary implant-supported denture patients with bar attachments. Stereognosis tests were carried out and the relationship between oral stereognostic ability and patient satisfaction was assessed with a satisfaction survey; Turkish version of oral health impact profile-14 (OHIP-TR-14). To compare differences in oral sensory function among individuals with natural dentition, complete denture wearers, and maxillary implant-supported denture wearers, tactile awareness (thickness perception threshold) and pressure awareness (threshold of lateral loading) were assessed...
October 24, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29053658/low-level-laser-therapy-for-treatment-of-neurosensory-disorders-after-orthognathic-surgery-a-systematic-review-of-randomized-clinical-trials
#8
M-A-V Bittencourt, L-R Paranhos, P-R-S Martins-Filho
BACKGROUND: Low-level laser has been widely used in Dentistry and many studies have focused on its application in oral surgeries. This study was conducted with the aim of searching for scientific evidence concerning the effectiveness of laser to reduce pain or paresthesia related to orthognathic surgery. MATERIAL AND METHODS: An electronic search was performed in PubMed, Scopus, Science Direct, LILACS, SciELO, CENTRAL, Google Scholar, OpenGrey, and ClinicalTrials...
November 1, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29042446/clinical-and-metabolic-consequences-of-l-serine-supplementation-in-hereditary-sensory-and-autonomic-neuropathy-type-1c
#9
Mari Auranen, Jussi Toppila, Saranya Suriyanarayanan, Museer A Lone, Anders Paetau, Henna Tyynismaa, Thorsten Hornemann, Emil Ylikallio
Hereditary sensory neuropathy type 1 (HSAN1) may be the first genetic neuropathy amenable to a specific mechanism-based treatment, as L-serine supplementation can be used to lower the neurotoxic levels of 1-deoxysphingolipids (1-deoxySL) that cause the neurodegeneration. The treatment is so far untested in HSAN1C caused by variants in the serine palmitoyl transferase subunit 2 (SPTLC2) gene. The aim of this study was to establish whether oral L-serine lowers 1-deoxySL in a patient with HSAN1C, to perform a dose escalation to find the minimal effective dose, and to assess the safety profile and global metabolic effects of the treatment...
October 17, 2017: Cold Spring Harbor Molecular Case Studies
https://www.readbyqxmd.com/read/29024230/%C3%AE-aminobutyric-acid-gaba-oral-rinse-reduces-capsaicin-induced-burning-mouth-pain-sensation-an-experimental-quantitative-sensory-testing-study-in-healthy-subjects
#10
Y Zhang, K Wang, L Arendt-Nielsen, B E Cairns
BACKGROUND: In burning mouth patients, analgesia after oral administration of clonazepam may result from modulation of peripheral γ-aminobutyric acid (GABA) receptors. METHODS: The effect of oral administration of test solutions (water, 0.5 mol/L or 0.05 mol/L GABA, 1% lidocaine) was investigated for the amelioration of pain and sensitivity induced by application of capsaicin (1%, 2 min) to the tongue of thirty healthy male and female subjects in this four-session, randomized, placebo-controlled, double-blinded, cross-over study...
October 11, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29023304/association-of-insulin-and-cholesterol-levels-with-peripheral-nervous-system-function-in-overweight-adults-a-3-year-follow-up
#11
Henri Isojärvi, Sirkka Keinänen-Kiukaanniemi, Mika Kallio, Kaisu Kaikkonen, Timo Jämsä, Juha Korpelainen, Raija Korpelainen
PURPOSE: The purpose of this prospective 3-year follow-up was to investigate the association of glucose, insulin, and cholesterol levels with peripheral nervous system function in overweight and obese subjects. METHODS: Forty nondiabetic overweight and obese adults were enrolled, of whom 29 completed the follow-up. Peripheral nervous system function was measured and defined by conduction studies of the peroneal motor nerve and the radial, sural, and medial plantar sensory nerves...
October 10, 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/28994815/in-vitro-characterization-of-the-electrophysiological-properties-of-colonic-afferent-fibers-in-rats
#12
Youqiang Meng, Li Dong, Biying Sun, Ping Luo, Guohua Zhang, Weifang Rong
Dysfunction of the colonic sensory nerves has been implicated in the pathophysiology of several common conditions, including functional and inflammatory bowel diseases and diabetes. Here, we describe a protocol for the in vitro characterization of the electrophysiological properties of colonic afferents in rats. The colorectum, with the intact pelvic ganglion (PG) attached, is removed from the rat; superfused with carbogenated Krebs solution in the recording chamber; and cannulated at the oral and anal ends to allow for distension...
September 27, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28967223/human-capability-in-the-perception-of-extensional-and-shear-viscosity
#13
Zhihong Lv, Jianshe Chen, Melvin Holmes
Shear and extensional deformation are two basic rheological phenomena which occur commonly in our daily life. Because of the very different nature of the two deformations, fluid materials may exhibit significant differences in their responses to shear and extensional forces. This work investigated the human perception of shear and extensional viscosity and tested the hypothesis that human have different discriminatory sensation mechanisms including scaling to the two deformations. A series of fluid samples were prepared using two common food thickeners, guar gum and sodium carboxylmethylcellulose (CMC-Na)...
October 2017: Journal of Texture Studies
https://www.readbyqxmd.com/read/28939430/do-non-nutritive-sweeteners-influence-acute-glucose-homeostasis-in-humans-a-systematic-review
#14
REVIEW
Robin M Tucker, Sze-Yen Tan
The human body associates sensory cues with metabolic consequences. Exposure to sweet-tasting sugars - even in the absence of ingestion - triggers physiological responses that are associated with carbohydrate digestion, absorption and metabolism. These responses include the release of insulin and incretin hormones, which work to reduce blood glucose. For this reason, non-nutritive sweeteners (NNS) have been posited to trigger similar physiological responses and reduce postprandial blood glucose concentrations...
December 1, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28929829/quantitative-sensory-testing-for-assessment-of-somatosensory-function-in-human-oral-mucosa-a-review
#15
Pin Zhou, Yaming Chen, Jinglu Zhang, Kelun Wang, Peter Svensson
OBJECTIVE: This narrative review provides an overview of the quantitative sensory testing (QST) to assess somatosensory function in human oral mucosa. MATERIAL AND METHODS: A literature search was conducted in the PubMed database to identify studies in vivo on human oral mucosa using QST methods. A list of 149 articles was obtained and screened. A total of 36 relevant articles remained and were read in full text. Manual search of the reference lists identified eight additional relevant studies...
September 20, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28929244/analyzing-polymeric-matrix-for-fabrication-of-a-biodegradable-microneedle-array-to-enhance-transdermal-delivery
#16
Kuo-Yuan Hwa, Vincent H S Chang, Yao-Yi Cheng, Yue-Da Wang, Pey-Shynan Jan, Boopathi Subramani, Min-Ju Wu, Bo-Kai Wang
Traditional drug delivery systems, using invasive, transdermal, and oral routes, are limited by various factors, such as the digestive system environment, skin protection, and sensory nerve stimulation. To improve the drug delivery system, we fabricated a polysaccharide-based, dissolvable microneedle-based array, which combines the advantages of both invasive and transdermal delivery systems, and promises to be an innovative solution for minimally invasive drug delivery. In this study, we designed a reusable aluminum mold that greatly improved the efficiency and convenience of microneedle fabrication...
September 19, 2017: Biomedical Microdevices
https://www.readbyqxmd.com/read/28899680/the-cephalic-phase-insulin-response-to-nutritive-and-low-calorie-sweeteners-in-solid-and-beverage-form
#17
Jaapna Dhillon, Janice Y Lee, Richard D Mattes
The purpose of the study was to examine the role of the cephalic phase insulin response (CPIR) following exposure to nutritive and low-calorie sweeteners in solid and beverage form in overweight and obese adults. In addition, the role of learning on the CPIR to nutritive and low-calorie sweetener exposure was tested. Sixty-four overweight and obese adults (age: 18-50years, BMI: 24-37kg/m(2), body fat percentage>25% for men and >32% for women) were sham-fed (at 2-minute intervals for 14min) a randomly assigned test load comprised of a nutritive (sucrose) or low-calorie sweetener (sucralose) in beverage or solid form in phase 1 of the study...
November 1, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28865394/clinical-measures-of-balance-in-people-with-type-two-diabetes-a-systematic-literature-review
#18
REVIEW
C J Dixon, T Knight, E Binns, B Ihaka, D O'Brien
Approximately 422 million people have diabetes mellitus worldwide, with the majority diagnosed with type 2 diabetes mellitus (T2DM). The complications of diabetes mellitus include diabetic peripheral neuropathy (DPN) and retinopathy, both of which can lead to balance impairments. Balance assessment is therefore an integral component of the clinical assessment of a person with T2DM. Although there are a variety of balance measures available, it is uncertain which measures are the most appropriate for this population...
October 2017: Gait & Posture
https://www.readbyqxmd.com/read/28860992/rewarding-effects-of-operant-dry-licking-behavior-on-neuronal-firing-in-the-nucleus-accumbens-core
#19
Enrico Patrono, Jumpei Matsumoto, Hiroshi Nishimaru, Yusaku Takamura, Ikhruud C Chinzorig, Taketoshi Ono, Hisao Nishijo
Certain eating behaviors are characterized by a trend of elevated food consumption. However, neural mechanisms mediating the motivation for food consumption are not fully understood. Food impacts the brain-rewarding-system via both oral-sensory and post-ingestive information. Recent studies have reported an important role of visceral gut information in mediating dopamine (DA) release in the brain rewarding system. This is independent of oral sensation, suggesting a role of the gut-brain-DA-axis in feeding behavior...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28856690/the-transcription-factor-phox2b-distinguishes-between-oral-and-non-oral-sensory-neurons-in-the-geniculate-ganglion
#20
Lisa Ohman-Gault, Tao Huang, Robin Krimm
Many basic characteristics of gustatory neurons remain unknown, partly due to the absence of specific markers. Some neurons in the geniculate ganglion project to taste regions in the oral cavity, whereas others innervate the outer ear. We hypothesized that the transcription factor Phox2b would identify oral cavity-projecting neurons in the geniculate ganglion. To test this possibility, we characterized mice in which Phox2b-Cre mediated gene recombination labeled neurons with tdTomato. Nerve labeling revealed that all taste neurons projecting through the chorda tympani (27%) and greater superficial petrosal nerves (15%) expressed Phox2b during development, whereas non-oral somatosensory neurons (58%) in the geniculate ganglion did not...
December 15, 2017: Journal of Comparative Neurology
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