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https://www.readbyqxmd.com/read/29471532/hyperparasitism-and-non-nidicolous-mating-by-male-ixodes-angustus-ticks-acari-ixodidae
#1
Lance A Durden, Robert F Gerlach, Kimberlee B Beckmen, Stephen E Greiman
Ixodes angustus (Neumann) (Acari: Ixodidae) is considered to be a nidicolous tick in that the entire life cycle can be completed in the host nest. Males of this tick have been reported to be rare on hosts because most mating occurs in the host nest and males typically do not feed on hosts. Collections of I. angustus in Alaska departed slightly from this paradigm in that nine males were collected from hosts, mostly in copulation with females that were attached to mammalian hosts. Non-nidicolous mating was therefore more common in I...
February 19, 2018: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29471369/genome-wide-association-study-of-stayability-and-heifer-pregnancy-in-red-angus-cattle
#2
S E Speidel, B A Buckley, R J Boldt, R M Enns, J Lee, M L Spangler, M G Thomas
Reproductive performance is the most important component of cattle production from the standpoint of economic sustainability of commercial beef enterprises. Heifer Pregnancy (HPG) and Stayability (STAY) genetic predictions are two selection tools published by the Red Angus Association of America (RAAA) to assist with improvements in reproductive performance. Given the importance of HPG and STAY to the profitability of commercial beef enterprises, the objective of this study was to identify QTL associated with both HPG and STAY in Red Angus cattle...
February 19, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29471321/overexpression-of-heparanase-in-mice-promoted-megakaryopoiesis
#3
Ying-Xia Tan, Hao Cui, Lu-Ming Wan, Feng Gong, Xiao Zhang, Israel Vlodavsky, Jin-Ping Li
Heparanase, an endo-glucuronidase that specifically cleaves heparan sulfate, is upregulated in several pathological conditions. In this study, we aimed to find a correlation of heparanase expression and platelets production. In the transgenic mice overexpressing human heparanase (Hpa-tg), hematological analysis of blood samples revealed a significantly higher number of platelets in comparison with wild-type (Ctr) mice, while no significant difference was found in leukocytes and red blood cell number between the two groups...
February 19, 2018: Glycobiology
https://www.readbyqxmd.com/read/29471252/relationship-between-monocytes-to-lymphocytes-ratio-and-axial-spondyloarthritis
#4
Yukai Huang, Weiming Deng, Shaoling Zheng, Fan Feng, Zhixiang Huang, Qidang Huang, Xin Guo, Zhengping Huang, Xuechang Huang, Xia Pan, Tianwang Li
BACKGROUND: Axial spondyloarthritis (axSpA) is a progressive, chronic, inflammatory skeletal disorder affecting the spine and sacroiliac joints. Many studies have shown that neutrophils, lymphocytes, monocytes, platelets, and red blood cells (RBCs) play important roles in the inflammatory process of axSpA. Neutrophils to lymphocytes ratio (NLR) and red blood cell distribution width (RDW) have been reported to be simple and inexpensive markers to indicate the disease activity of axSpA...
February 19, 2018: International Immunopharmacology
https://www.readbyqxmd.com/read/29471234/influences-of-motorcycle-rider-and-driver-characteristics-and-road-environment-on-red-light-running-behavior-at-signalized-intersections
#5
Auearree Jensupakarn, Kunnawee Kanitpong
In Thailand, red light running is considered as one of the most dangerous behaviors at intersection. Red light running (RLR) behavior is the failure to obey the traffic control signal. However, motorcycle riders and car drivers who are running through red lights could be influenced by human factors or road environment at intersection. RLR could be advertent or inadvertent behavior influenced by many factors. Little research study has been done to evaluate the contributing factors influencing the red-light violation behavior...
February 19, 2018: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29471147/blue-light-versus-red-light-for-photodynamic-therapy-of-basal-cell-carcinoma-in-patients-with-gorlin-syndrome-a-bilaterally-controlled-comparison-study
#6
Edward V Maytin, Urvashi Kaw, Muneeb Ilyas, Judith A Mack, Bo Hu
BACKGROUND: Photodynamic therapy (PDT) is a non-scarring alternative for treating basal cell carcinoma (BCC) in patients with Basal Cell Nevus Syndrome (BCNS), also known as Gorlin syndrome. In Europe, red light (635 nm) is the predominant source for PDT, whereas in the United States blue light (400 nm) is more widely available. The objective of this study was to conduct a head-to-head comparison of blue light and red light PDT in the same BCNS patients. METHODS: In a pilot study of three patients with 141 BCC lesions, 5-aminolevulinate (20% solution) was applied to all tumors...
February 19, 2018: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/29470953/cat-preantral-follicle-survival-after-prolonged-cooled-storage-followed-by-vitrification
#7
Jorge Luis Araújo Martins, Maria Denise Lopes, Fabiana Ferreira de Souza, Fabio Sossai Possebon, Gudrun Wibbelt, Katarina Jewgenow
The aim of this study was to investigate the impact of prolonged storage at 4 °C on survival of cat preantral follicles (PAFs) pre- and post-vitrification. Ovaries were obtained from 12 queens and transported at 4 ºC within 2-6 h. Parts of the ovaries were stored for an additional 24 h or 72 h. The ovarian cortex was dissected, analyzed for viability (neutral red - NR) and morphology (histology - HE and ultrastructural analysis by TEM) and vitrified. We used 2 mm biopsy punches to obtain equal size pieces as the experimental units...
February 19, 2018: Cryobiology
https://www.readbyqxmd.com/read/29470849/direct-integration-of-red-nir-emissive-ceramic-like-anm6xi8xa6-metal-cluster-salts-in-organic-copolymers-using-supramolecular-interactions
#8
Yann Molard, Malo Robin, Noée Dumait, Maria Amela-Cortes, Claire Roiland, Maxime Harnois, Emmanuel Jacques, Hervé Folliot
Hybrid nanomaterials made of inorganic nanocomponents dispersed in an organic host raise an increasing interest as low-cost solution-processable functional materials. However, preventing phase segregation while allowing a high inorganic doping content remains a major challenge, and usual methods require a functionalization step prior integration. Herein, we report a new approach to design such nanocomposite in which lead-free and cadmium-free ceramic-like metallic nanocluster compounds are embedded at 10 wt % in organic copolymers, without any functionalization...
February 22, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29470827/in-vitro-characterization-and-evaluation-of-the-cytotoxicity-effects-of-nisin-and-nisin-loaded-pla-peg-pla-nanoparticles-on-gastrointestinal-ags-and-kyse-30-hepatic-hepg2-and-blood-k562-cancer-cell-lines
#9
Fariba Goudarzi, Asadollah Asadi, Maryam Afsharpour, Robab Hassanvand Jamadi
The aim of this study was an in vitro evaluation and comparison of the cytotoxic effects of free nisin and nisin-loaded PLA-PEG-PLA nanoparticles on gastrointestinal (AGS and KYSE-30), hepatic (HepG2), and blood (K562) cancer cell lines. To create this novel anti-cancer drug delivery system, the nanoparticles were synthesized and then loaded with nisin. Subsequently, their biocompatibility, ability to enter cells, and physicochemical properties, including formation, size, and shape, were studied using hemolysis, fluorescein isothiocyanate (FITC), Fourier transform infrared (FTIR) spectroscopy, dynamic light scattering (DLS), and scanning electron microscopy (SEM), respectively...
February 22, 2018: AAPS PharmSciTech
https://www.readbyqxmd.com/read/29470628/bladder-debris-on-ultrasound-in-the-emergency-department-correlation-with-urinalysis
#10
Ghaneh Fananapazir, Behrad Golshani, Ling-Xin Chen, John P McGahan, Angelo M de Mattos, Michael T Corwin
PURPOSE: To evaluate the correlation between the presence of bladder debris on ultrasound and urinalysis results in the emergency department setting. METHODS: Adult patients presenting to the emergency department with an ultrasound of the bladder and a urinalysis performed within 24 h of the ultrasound were included in this retrospective study. Two radiologists in consensus evaluated for the presence or absence of debris within the bladder. Urinalysis results were recorded including continuous variables (specific gravity and pH) and categorical variables (presence of occult blood, bilirubin, ketones, glucose, protein, urobilinogen, nitrite, leukocyte esterase, white blood cells, and red blood cells)...
February 22, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29470615/pre-dosing-with-lilotomab-prior-to-therapy-with-177-lu-lilotomab-satetraxetan-significantly-increases-the-ratio-of-tumor-to-red-marrow-absorbed-dose-in-non-hodgkin-lymphoma-patients
#11
Caroline Stokke, Johan Blakkisrud, Ayca Løndalen, Jostein Dahle, Anne C T Martinsen, Harald Holte, Arne Kolstad
PURPOSE: 177 Lu-lilotomab satetraxetan is a novel anti-CD37 antibody radionuclide conjugate for the treatment of non-Hodgkin lymphoma (NHL). Four arms with different combinations of pre-dosing and pre-treatment have been investigated in a first-in-human phase 1/2a study for relapsed CD37+ indolent NHL. The aim of this work was to determine the tumor and normal tissue absorbed doses for all four arms, and investigate possible variations in the ratios of tumor to organs-at-risk absorbed doses...
February 22, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29470539/divergence-in-male-sexual-odor-signal-and-genetics-across-populations-of-the-red-mason-bee-osmia-bicornis-in-europe
#12
Taina Conrad, Robert J Paxton, Günter Assum, Manfred Ayasse
In some insect species, females may base their choice for a suitable mate on male odor. In the red mason bee, Osmia bicornis, female choice is based on a male's odor bouquet as well as its thorax vibrations, and its relatedness to the female, a putative form of optimal outbreeding. Interestingly, O. bicornis can be found as two distinct color morphs in Europe, which are thought to represent subspecies and between which we hypothesize that female discrimination may be particularly marked. Here we investigated (i) if these two colors morphs do indeed represent distinct, reproductively differentiated populations, (ii) how odor bouquets of male O...
2018: PloS One
https://www.readbyqxmd.com/read/29470387/assessment-of-chitosan-based-hydrogel-and-photodynamic-inactivation-against-propionibacterium-acnes
#13
Maria Lucia Frade, Sarah Raquel de Annunzio, Giovana Maria Fioramonti Calixto, Francesca Damiani Victorelli, Marlus Chorilli, Carla Raquel Fontana
Chitosan (CH) is a biopolymer that exhibits a number of interesting properties such as anti-inflammatory and antibacterial activity and is also a promising platform for the incorporation of photosensitizing agents. This study aimed to evaluate the efficacy of antimicrobial activity of chitosan hydrogel formulation alone and in combination with the methylene blue (MB) associated with antimicrobial photodynamic therapy (aPDT) against planktonic and biofilm phase of Propionibacterium acnes . Suspensions were sensitized with 12...
February 22, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29470370/examining-diagnosing-and-treating-benign-anorectal-conditions
#14
Priscilla Marsicovetere
Anorectal pain and discomfort are common complaints in the general population, and can stem from a number of possible causes. Often, the complaints present in the primary care setting and can be adequately evaluated, diagnosed, and treated without the need for referral to a colorectal specialist. Proper evaluation and diagnosis can result in prompt, effective patient care. Recognition of red flags should prompt immediate referral to a colorectal specialist for further evaluation.
March 2018: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/29470127/telemedicine-physical-examination-utilizing-a-consumer-device-demonstrates-poor-concordance-with-in-person-physical-examination-in-emergency-department-patients-with-sore-throat-a-prospective-blinded-study
#15
Moneeb Akhtar, Paul G Van Heukelom, Azeemuddin Ahmed, Rachel D Tranter, Erinn White, Nathaniel Shekem, David Walz, Catherine Fairfield, J Priyanka Vakkalanka, Nicholas M Mohr
BACKGROUND: Telemedicine allows patients to connect with healthcare providers remotely. It has recently expanded to evaluate low-acuity illnesses such as pharyngitis by using patients' personal communication devices. The purpose of our study was to compare the telemedicine-facilitated physical examination with an in-person examination in emergency department (ED) patients with sore throat. MATERIALS AND METHODS: This was a prospective, observational, blinded diagnostic concordance study of patients being seen for sore throat in a 60,000-visit Midwestern academic ED...
February 22, 2018: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/29470077/efficient-upper-excited-state-fluorescence-in-an-organic-hyperbolic-metamaterial
#16
Yufei Shen, Yixin Yan, Alyssa N Brigeman, Hoyeon Kim, Noel C Giebink
Upper-excited state emission is not usually observed from molecules owing to competition with much faster non-radiative relaxation pathways; however, it can be made more efficient by modifying the photonic density of states to enhance the radiative decay rate. Here, we show that embedding the small molecule zinc tetraphenylporphyrin (ZnTPP) in a hyperbolic metamaterial enables an ~18-fold increase in fluorescence intensity from the second singlet excited state (S2 ) relative to that from the lowest singlet excited state (S1 )...
February 22, 2018: Nano Letters
https://www.readbyqxmd.com/read/29469948/sensory-acceptability-of-iron-fortified-red-lentil-lens-culinaris-medik-dal
#17
Rajib Podder, Shaan M Khan, Bunyamin Tar'an, Robert T Tyler, Carol J Henry, Chowdhury Jalal, Phyllis J Shand, Albert Vandenberg
Panelists in Saskatoon, Canada (n = 45) and Dhaka, Bangladesh (n = 98) participated in sensory evaluations of the sensory properties of both cooked and uncooked dehulled red lentil dal fortified with FeSO4 ·7H2 O, NaFeEDTA or FeSO4 ·H2 O at fortificant Fe concentrations of 800, 1,600 (both cooked and uncooked), or 2,800 ppm. Appearance, odor, and overall acceptability of cooked and uncooked samples were rated using a 9-point hedonic scale (1 = dislike extremely to 9 = like extremely). Taste and texture were rated for the cooked samples prepared as typical south Asian lentil meals...
February 22, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29469832/upconversion-luminescence-of-ba-3-la-po-4-3-yb-3-er-3-tm-3-phosphors-for-optimal-temperature-sensing
#18
Jiafeng Cao, Jia Zhang, Xiaowei Li
To explore new upconversion (UC) luminescent materials for optical temperature sensing, a series of Ba3 La1-x (PO4 )3 :0.1Yb3+ ,xEr3+ (abbreviated as BLP:0.1Yb3+ , xEr3+ , 0.01≤x≤0.03) and Ba3 La1-y (PO4 )3 :0.1Yb3+ ,yTm3+ (abbreviated as BLP:0.1Yb3+ , yTm3+ , 0.005≤y≤0.015) phosphors was designed. For Yb3+ -Er3+ codoped BLP, the UC emission spectra exhibit a gradual enhancement with increasing pump power, and two-photon process for the green and red emissions of Er3+ has been confirmed by studying the dependence of UC emission intensities on excitation power...
February 20, 2018: Applied Optics
https://www.readbyqxmd.com/read/29469816/white-light-emitting-device-based-on-single-phase-cds-quantum-dots
#19
Feng Li, Chao Nie, Lai You, Xiao Jin, Qin Zhang, Yuancheng Qin, Feng Zhao, Yinglin Song, Zhongping Chen, Qinghua Li
White light emitting diodes (WLEDs) based on quantum dots (QDs) are emerging as robust candidates for white light source, however they are suffering from the problem of energy loss resulted from the re-absorption and self-absorption among the employed QDs of different peak wavelengths. It still remains a challenging task to construct WLEDs based on single-phase QD emitters. Here, CdS QDs with short synthesis time is introduced to the fabrication of WLEDs. With short synthesis time, on one hand, CdS QD of small diameter with blue emission can be obtained...
February 22, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29469798/complete-resolution-of-erythema-elevatum-diutinum-using-oral-sulfasalazine
#20
Michael L Chen, Agata Chlopik, Maija P Hoang, Gideon P Smith
Erythema elevatum diutinum (EED) is a rare, chronic small-vessel vasculitis that presents as firm, red, violaceous, or brown papules and nodules on the extensor surfaces of the limbs. Oral dapsone is considered first-line therapy for EED; in the current case report, a patient presenting with EED began dapsone treatment and symptoms subsided within two weeks. Seven months later, the patient became pregnant and stopped dapsone owing to her concerns with dapsone use during pregnancy, resulting in recurrence of EED symptoms...
October 15, 2017: Dermatology Online Journal
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