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Ivana Hegeduš, Jakov Milić, Anita Ćosić, Krunoslav Buljan, Ines Drenjančević
AIM: This study aimed to assess the effect of acute hyperoxia on cerebral and systemic heamodynamics and the plasma concentration of prostacyclin and thromboxane in patients with stroke. METHODS: Mean blood flow velocity (MBFV), pulsatility and resistance indices of the middle cerebral artery using transcranial Doppler ultrasound before and during acute hyperoxia (4 L of 100%O2 /15' over facial mask) in 92 participants - 25 patients with acute ischaemic stroke (AIS) that occurred within 72 hours and diabetes mellitus (SPDM), 26 AIS patients without DM (SP) and in 41 healthy controls (HS), were measured...
2017: Brain Injury: [BI]
Torpong Thongngarm, Paraya Assanasen, Panitan Pradubpongsa, Pongsakorn Tantilipikorn
BACKGROUND: The recommended drug for moderate to severe chronic rhinitis is intranasal steroids (INS). However, nasal congestion could be refractory and need additional treatments. OBJECTIVE: We sought to explore the benefit of oxymetazoline (Oxymet) plus INS on nasal congestion without inducing rhinitis medicamentosa. METHODS: We performed a 60-week, randomised, double-blind clinical trial in 50 patients, 18 years of age or greater, with chronic rhinitis who had used INS and cetirizine and still had nasal congestion...
March 2016: Asian Pacific Journal of Allergy and Immunology
C Brinkmann, R Hermann, E Rühl, H Kerzel, L Reinhardt, M Grau, J Latsch, M Kohl-Bareis, W Bloch, K Brixius
Metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM) are associated with macro- and microcirculatory complications that reduce physical performance. Wearing compression garments to potentially optimize hemodynamics has been discussed. This study investigates the effects of wearing compression stockings on physical performance-related variables in type 2 diabetic men with metabolic syndrome (n=9, 57±12 years, BMI: 36±4 kg/m(2)). Participants served as their own controls in a randomized 3*3 crossover study wearing below-knee stockings with either compression (24 or 30 mmHg ankle pressure) or no compression...
May 2016: International Journal of Sports Medicine
G C Behera, S K Behera, R K Jena, V S Bharati
To estimate the concentration of methemoglobin (MetHb) in malaria patients and correlate with severity of malaria infection. This prospective study included 30 untreated cases of malaria confirmed by Quantitative Buffy Coat (QBC) test and 30 age sex matched non-malarial cases taken as controls. All the patients underwent thorough clinical examination and routine biochemical investigation. Methemoglobin levels were estimated by spectrophotometric (co-oxymeter) method on day 1 and day 10 of diagnosis of all study group patients and correlated with clinical profile and severity...
March 2016: Indian Journal of Hematology & Blood Transfusion
Michelangelo Bruno Casali, Luca Sironi, Marina Caligara, Alberto Blandino, Silvia Circelli, Davide Schiavi, Cristina Cattaneo
Dealing with burnt bodies, the forensic pathologist must first of all answer the question whether the victim was alive at the moment of the fire. This study aims at clarifying whether some human solid tissues may be reliably used for the forensic diagnosis of Co poisoning on burnt bodies providing no collectable blood during the autopsy. From 34 selected cases, both cardiac blood and parenchymal samples were collected to perform CO-oxymeter, spectrophotometry, and gas chromatography tests: blood CO estimations (blood COHb% and blood[CO]) and parenchymal[CO] values have been compared with special focus on R values...
March 2015: Journal of Forensic Sciences
Axel Fudickar, Sarah Kunath, Dana Voß, Markus Siggelkow, Erol Cavus, Markus Steinfath, Berthold Bein
BACKGROUND: Ischemic or volatile anesthetic preconditioning is defined as tissue protection from impending ischemic cell damage by repetitive short periods of tissue exposure to ischemia or volatile anesthetics. Objective of this study was to elucidate, if ischemic preconditioning and pharmacological preconditioning with sevoflurane have effects on muscle tissue oxygen saturation in patients undergoing surgical revascularization of the lower limb. METHODS: In this prospective randomized pilot study ischemic and pharmacological (sevoflurane) preconditioning was performed in 40 patients with lower limb arterial occlusive disease undergoing surgical revascularization...
2014: BMC Anesthesiology
Keld Poulsen, Justyna Mc Bahl, Anja H Simonsen, Steen G Hasselbalch, Niels Hh Heegaard
BACKGROUND: Transthyretin (TTR), an abundant protein in cerebrospinal fluid (CSF), contains a free, oxidation-prone cysteine residue that gives rise to TTR isoforms. These isoforms may reflect conditions in vivo. Since increased oxidative stress has been linked to neurodegenerative disorders such as Alzheimer's disease (AD) it is of interest to characterize CSF-TTR isoform distribution in AD patients and controls. Here, TTR isoforms are profiled directly from CSF by an optimized immunoaffinity-mass spectrometry method in 76 samples from patients with AD (n = 37), mild cognitive impairment (MCI, n = 17)), and normal pressure hydrocephalus (NPH, n = 15), as well as healthy controls (HC, n = 7)...
2014: Clinical Proteomics
Shiv Sagar Gupta, Dipti Gothi, Gurpreet Narula, Joydeep Sircar
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is associated with clinically relevant extra pulmonary manifestations; one of them is weight loss. However, there are very few studies from North India available in relation to body mass index (BMI) and Oxygen saturation (SpO2) with COPD. AIMS: To study the prevalence of undernutrition among stable COPD patients and correlation of COPD severity with SpO2 and BMI. SETTINGS AND DESIGN: A prospective study was carried out at a tertiary care hospital...
January 2014: Lung India: Official Organ of Indian Chest Society
S Uzun, Y Yuce, A Erden, U Aypar
BACKGROUND: Combination of local and regional anesthetic agents are widely used in emergency and surgical setting and the interaction between the medications used in general anesthesia and these local and/or regional anesthetic becomes a growing concern in current patient management system. The interaction between general anesthetic agents and the local anesthetic agents given epidurally, spinally, intravenously or intramuscularly and the effects of BIS monitorisation on combined propofol-remifentanil anesthesia are examined in several studies...
2014: European Review for Medical and Pharmacological Sciences
H Ben Ahmed, H Boussaid, I Hamdi, M R Boujnah
BACKGROUND: Obstructive sleep apnea has been implicated in the pathogenesis and aggravation of coronary atherosclerosis. However, it remains underdiagnosed in cardiology practice. AIM: The aim of this study was to determine the prevalence of obstructive sleep apnea and the predictors of severe sleep apnea in patients admitted for ST elevation myocardial infarction. METHODS: This was a prospective study which has included 120 patients hospitalized for ST elevation myocardial infarction, from April 2011 to March 2012...
April 2014: Annales de Cardiologie et D'angéiologie
Ashkan Rashad, Ralf Smeets, Madiha Rana, Behnam Bohluli
PURPOSE: Significant vasovagal reaction is one of the untoward events in the course of simple extractions. The present study then aimed to record the patients' heart rate during the extraction procedure. MATERIALS AND METHODS: Informed consents were obtained in advance. Patients were placed in the dental chair and their heart rate was measured before /and prior to the anesthetic injection, during, and after dental extraction on a pulse oxymeter device. Data were analyzed using paired t-test...
2013: Head & Face Medicine
Naoki Nakashima, Tatsuo Hiramatsu, Partha Pratim Ghosh, Rafiqul Islam, Kunihisa Kobayashi, Toyoshi Inoguchi
Management system of chronic diseases in developing countries and post-disaster situation has been required. Body area network (BAN, IEEE 802.15.6) is expected to be useful in medical field. To evaluate BAN standard, we are implementing BAN in our attaché case type sensor set named "Portable Health Clinic" (PHC), and conducting systematic health checkup in rural and urban areas in Bangladesh. (Methods) In the PHC, we packed weight scale, blood pressure meter, blood sugar meter, body thermometer, pulse oxymeter, as electrical devices, and tape measure (for height, waist and hip), urine test tape (for urine sugar, urine protein and urobilinogen) as no-electrical devices...
2013: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Sinem Nedime Sökücü, Levent Karasulu, Levent Dalar, Cengiz Ozdemir, Ekrem Cengiz Seyhan, Senay Aydin, Sedat Altin
AIM: Obstructive sleep apnea syndrome (OSAS) may promote hyperglycemia and insulin resistance. Our aim is to investigate the effect of OSAS on the fasting plasma glucose, glycosylated hemoglobin (HbA1c), and C reactive protein (CRP) in nondiabetic patients. MATERIAL AND METHODS: Blood parameters of consecutive 90 non diabetic patients whom polysomnografic evaluations were done in our sleep laboratory was evaluated. Among these 61 patients with normal fasting blood glucose were classified due to their apne-hipopnea index (AHI) as mild (n=16, 26...
August 2013: Archivos de Bronconeumología
Richard L Doyle, Ian J Godwin, Michael P Brandon, Michael E G Lyons
This paper presents a review of the redox and electrocatalytic properties of transition metal oxide electrodes, paying particular attention to the oxygen evolution reaction. Metal oxide materials may be prepared using a variety of methods, resulting in a diverse range of redox and electrocatalytic properties. Here we describe the most common synthetic routes and the important factors relevant to their preparation. The redox and electrocatalytic properties of the resulting oxide layers are ascribed to the presence of extended networks of hydrated surface bound oxymetal complexes termed surfaquo groups...
September 7, 2013: Physical Chemistry Chemical Physics: PCCP
Tamás Végh, S Szatmári, M Juhász, I László, A Vaskó, I Takács, L Szegedi, B Fülesdi
BACKGROUND: Previously a report has suggested that administration of lung protective strategy for one-lung ventilation(OLV) results in oxygen desaturation of the brain parenchyma. The aim of our work was to confirm that the maintenance of normocapnia during protective OLV strategy results in alteration of cerebral blood fl ow and cerebral oxygen saturation as compared to double-lung ventilation. METHODS: Data were obtained from 24 patients undergoing thoracic surgery...
June 2013: Acta Physiologica Hungarica
Pablo Cruces, Alejandro Donoso, Jorge Valenzuela, Franco Díaz
BACKGROUND: Little is known about the efficacy and safety of recruitment maneuvers (RMs) in pediatric patients with acute respiratory distress syndrome (ARDS). We therefore assessed the effects on gas exchange and lung mechanics and the possible detrimental effects of a sequential lung RMs and decremental positive end-expiratory pressure (PEEP) titration in pediatric ARDS patients. METHODS: We enrolled patients <15 years of age with ARDS, progressive hypoxemia, <72 hr of mechanical ventilation, and hemodynamic stability...
November 2013: Pediatric Pulmonology
R Padma, Saakshi Goel, M Shriniwas, Annaji Shreedhara, Sachin Malagi, B Radhika, B S Jagadish Pai
BACKGROUND AND AIM: Monitoring is the global method of observation and data recording in relation to body organ and system function that afford constant information to ensure continuous evalutation of the patient's physical condition. Basic monitoring provides essential information for assessing the vital signs, both circulatory and respiratory, and fundamentally comprises the control of blood pressure (BP) and heart rate (HR) and rhythm. Pulse oxymetry is used to record HR and oxygen saturation...
September 1, 2012: Journal of Contemporary Dental Practice
Keyne Charlot, Aurélien Pichon, Jean-Paul Richalet, Didier Chapelot
A carbohydrate (CHO) solution consumed before exposure to hypoxia has been reported to reduce arterial oxygen desaturation at rest. The purpose of this study was to determine whether this effect occurred during exercise and when the CHO load is part of a meal. Eleven male subjects (mean age 20.1 ± 1.8 years, BMI 24.3 ± 2.4 kg m(2)) consumed either a high-CHO (2,340 kJ, 70 % CHO, 12 % protein) or an isoenergetic high-protein (35 % CHO, 48 % protein) breakfast meal 60 min before being exposed to 15 min of hypoxia (F(I)O(2) = 13...
March 2013: European Journal of Applied Physiology
Gill R Tsouri, Survi Kyal, Sohail Dianat, Lalit K Mestha
Nonobtrusive pulse rate measurement using a webcam is considered. We demonstrate how state-of-the-art algorithms based on independent component analysis suffer from a sorting problem which hinders their performance, and propose a novel algorithm based on constrained independent component analysis to improve performance. We present how the proposed algorithm extracts a photoplethysmography signal and resolves the sorting problem. In addition, we perform a comparative study between the proposed algorithm and state-of-the-art algorithms over 45 video streams using a finger probe oxymeter for reference measurements...
July 2012: Journal of Biomedical Optics
Wafa Elias, Nimer Assy, Ibrahim Elias, Tomer Toledo, Mustafa Yassin, Abdalla Bowirrat
OBJECTIVE: To determine whether the consumption of tobacco used in Water-Pipe by drivers increases the risk of a motor vehicle collision as a consequence of hypoxia. DESIGN: Analytical case-control study. DATA SOURCES: Seventy exclusive Water-Pipe smokers (Experimental Group--EG)--mean age ± SD: 29.47 ± 10.45 years; mean number of weekly WPS, (6.9 ± 3.7); mean duration of WPS (WPS) is (7.5 ± 2.1 years)--and thirty non-smoker (Control Group--CG; mean age ± SD: 36...
2012: Journal of Translational Medicine
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