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https://www.readbyqxmd.com/read/28110156/maternal-childhood-trauma-postpartum-depression-and-infant-outcomes-avoidant-affective-processing-as-a-potential-mechanism
#1
Karmel W Choi, Kathleen J Sikkema, Bavi Vythilingum, Lut Geerts, Sheila C Faure, Melissa H Watt, Annerine Roos, Dan J Stein
BACKGROUND: Women who have experienced childhood trauma may be at risk for postpartum depression, increasing the likelihood of negative outcomes among their children. Predictive pathways from maternal childhood trauma to child outcomes, as mediated by postpartum depression, require investigation. METHODS: A longitudinal sample of South African women (N=150) was followed through pregnancy and postpartum. Measures included maternal trauma history reported during pregnancy; postpartum depression through six months; and maternal-infant bonding, infant development, and infant physical growth at one year...
January 8, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28105497/comparison-of-traditional-and-emerging-surgical-therapies-for-lower-urinary-tract-symptoms-in-men-a-review
#2
Christopher Smith, Paul Craig, Shayandokht Taleb, Shamar Young, Jafar Golzarian
Lower urinary tract symptoms (LUTS) are one of the most common health issues in men and pose a significant economic challenge in healthcare. Transurethral resection of the prostate (TURP) remains the gold standard surgical treatment for medically refractive LUTS secondary to benign prostatic hyperplasia. The institution of medical therapy and the development of several minimally invasive surgical therapies (MISTs) began in the 1980's and 1990's. Together, these therapies brought about a change in the natural course of the disease, stimulating investigation into the economic consequences of various management approaches...
January 19, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28104419/pelvic-hardware-eroding-into-the-bladder-a-rare-case-presentation-of-gross-hematuria-bladder-pain-and-refractory-luts
#3
Kristen E Gurtner, Jonathan A Israel, Michael R Pinsky, James F Mautner, June B Miguez, Daniel J Canter
We present a 60 year-old male who presented with gross hematuria, refractory lower urinary tract symptoms, and increasing bladder pain for 3 months. The patient had a prior history of a motorcycle accident and pelvic fracture requiring an extensive pelvic open reduction and internal fixation. During evaluation, the patient was found to have an orthopedic screw from his hardware eroding through the left lateral wall of his bladder and irritating his trigone. The patient underwent pelvic exploration with open cystotomy and hardware removal with the orthopedic service...
January 16, 2017: Urology
https://www.readbyqxmd.com/read/28102554/what-are-the-predicting-factors-for-the-therapeutic-effects-of-dutasteride-in-male-patients-with-lower-urinary-tract-symptoms-investigation-using-a-urodynamic-study
#4
Yoshihisa Matsukawa, Masashi Kato, Yasuhito Funahashi, Tsuyoshi Majima, Tokunori Yamamoto, Momokazu Gotoh
AIMS: We investigated predicting factors for the therapeutic effects of dutasteride in patients with lower urinary tract symptoms (LUTS) due to benign prostatic enlargement (BPE) based on a urodynamic study (UDS). METHODS: This was a single-center, prospective study involving 120 male outpatients with LUTS. They received 0.5 mg of dutasteride per day for 12 months. IPSS, OABSS, IPSS-QOL, and UDS were used for assessing subjective and objective symptoms prior to and 12 months after administration...
January 19, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28101223/modulatory-effect-of-luteolin-on-redox-homeostasis-and-inflammatory-cytokines-in-a-mouse-model-of-liver-cancer
#5
Qiang Zhang, Jie Yang, Jun Wang
Liver cancer is one of the leading causes of cancer-associated mortality worldwide. Due to changes in lifestyle and daily exposure to various chemicals, which may lead to chemical intoxication, liver cancer has become a prominent disease in humans. Chemical-induced carcinogenesis in experimental animals has become a reliable model for the investigation of liver cancer-associated biological alterations that may mimic human hepatic cancer. Liver cancer in BALB/c mice was induced by administering diethylnitrosamine (DN) in drinking water for 6 weeks...
December 2016: Oncology Letters
https://www.readbyqxmd.com/read/28098199/optogenetic-modulation-of-urinary-bladder-contraction-for-lower-urinary-tract-dysfunction
#6
Jae Hong Park, Jin Ki Hong, Ja Yun Jang, Jieun An, Kyu-Sung Lee, Tong Mook Kang, Hyun Joon Shin, Jun-Kyo Francis Suh
As current clinical approaches for lower urinary tract (LUT) dysfunction such as pharmacological and electrical stimulation treatments lack target specificity, thus resulting in suboptimal outcomes with various side effects, a better treatment modality with spatial and temporal target-specificity is necessary. In this study, we delivered optogenetic membrane proteins, such as channelrhodopsin-2 (ChR2) and halorhodopsin (NpHR), to bladder smooth muscle cells (SMCs) of mice using either the Cre-loxp transgenic system or a viral transfection method...
January 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28094878/characterization-of-cellulose-degrading-bacteria-from-the-larval-gut-of-the-white-grub-beetle-lepidiota-mansueta-coleoptera-scarabaeidae
#7
Gautam Handique, Amrita Phukan, Badal Bhattacharyya, Abu Adil Lutful Haque Baruah, Syed Wasifur Rahman, Rajen Baruah
The goal of this study is to identify and characterize the cellulose degrading microorganisms in the larval gut of the white grub beetle, Lepidiota mansueta. Thirty bacterial strains were isolated and tested for cellulolytic activity using soluble carboxymethyl cellulose (CMC) degrading assays. Of these strains, five (FGB1, FB2, MB1, MB2, and HB1) degrade cellulose. Cellulolytic activity was determined based on formation of clear zone and cellulolytic index on CMC plate media. The highest cellulolytic index (2...
January 17, 2017: Archives of Insect Biochemistry and Physiology
https://www.readbyqxmd.com/read/28087357/early-effect-of-bariatric-surgery-on-urogenital-function-in-morbidly-obese-men
#8
Maha Aleid, Asif Muneer, Sara Renshaw, Jason George, Andrew D Jenkinson, Marco Adamo, Mohamed Elkalaawy, Rachel Batterham, David J Ralph, Majid Hashemi, Selim Cellek
INTRODUCTION: Obesity is an independent risk factor for erectile dysfunction (ED) and lower urinary tract symptoms (LUTS). Bariatric surgery has been shown to improve erectile function and urinary symptoms in medium- to long-term studies (3- to 12-month postoperative follow-up). AIM: To investigate the early effect (1 month postoperatively) of bariatric surgery on ED and LUTS, which has not previously been investigated. METHODS: Morbidly obese men (body mass index > 35 kg/m(2)) undergoing bariatric surgery were asked to complete the International Index of Erectile Function (IIEF) and International Prostate Symptom Score (IPSS) questionnaires before surgery and 1, 3, and 6 months after surgery...
January 10, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28087281/mtuepa-trans-urethral-monopolar-enucleation-of-prostatic-adenoma-preliminary-report
#9
Vito Pansadoro, Paolo Emiliozzi, Gianluca Del Vecchio, Marco Martini, Paolo Scarpone, Francesco Del Giudice, Domenico Veneziano, Aldo Brassetti, Christophe Assenmacher
OBJECTIVES: To describe preliminary results of our monopolar Transurethral Enucleation of Prostatic Adenoma (mTUEPA). METHODS: A consecutive series of patient treated with mTUEPA, a retrograde enucleation of the prostatic adenoma performed by means of a standard monopolar resectoscope, were prospectively enrolled. Symptoms, uroflometry parmeters and post voiding residual (PVR) were assessed at baseline and 1, 6 and 12 months post-operatively. Prostate volume (PV) was evaluated at baseline by means of transrectal ultrasound...
January 10, 2017: Urology
https://www.readbyqxmd.com/read/28079355/self-assembled-architectures-of-alkynylplatinum-ii-amphiphiles-and-their-structural-optimization-a-balance-of-the-interplay-among-pt%C3%A2-%C3%A2-%C3%A2-pt-%C3%AF-%C3%AF-stacking-and-hydrophobic-hydrophobic-interactions
#10
Heidi Li-Ki Fu, Charlotte Po, Sammual Yu-Lut Leung, Vivian Wing-Wah Yam
A series of alkynylplatinum(II) terpyridine complexes with triethylene glycol units was synthesized, and their self-assembly properties were investigated in solution by UV-vis absorption, emission, and (1)H NMR spectroscopy. The aggregation behaviors of several water-soluble complexes were investigated in aqueous media. Some of them were found to give rise to uniform fibers, suggesting the important role that triethylene glycol units has in regulating their self-assembly properties. Further modifications of these structures through the incorporation of alkyl chains and changes in counter-anions have rendered the complexes more amphiphilic in nature, and the effect of their alkyl chain lengths was studied and optimized...
January 12, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28078524/vesico-urethral-anastomosis-vua-evaluation-of-short-and-long-term-outcome-after-robot-assisted-laparoscopic-radical-prostatectomy-rarp-selective-cystogram-to-improve-outcome
#11
C Tillier, H A M van Muilekom, J Bloos-van der Hulst, N Grivas, H G van der Poel
The role of a cystogram to assess the vesico-urethral anastomosis (VUA) after robot-assisted laparoscopic radical prostatectomy (RARP) has been debated. Early catheter removal without cystogram was reported to be associated with a trend towards an increased risk of acute urinary retention (AUR). In two cohorts we studied the effects of VUA leakage on cystogram and functional outcome after RARP. Cohort A contained 1390 consecutive men that routinely underwent a cystogram after RARP. Transurethral catheter (TUC) was removed in the absence of VUA leakage or minimal leakage on subsequent repeat cystogram...
January 12, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/28078386/early-differences-in-islets-from-prediabetic-nod-mice-combined-microarray-and-proteomic-analysis
#12
Inne Crèvecoeur, Valborg Gudmundsdottir, Saurabh Vig, Fernanda Marques Câmara Sodré, Wannes D'Hertog, Ana Carolina Fierro, Leentje Van Lommel, Conny Gysemans, Kathleen Marchal, Etienne Waelkens, Frans Schuit, Søren Brunak, Lut Overbergh, Chantal Mathieu
AIMS/HYPOTHESIS: Type 1 diabetes is an endocrine disease where a long preclinical phase, characterised by immune cell infiltration in the islets of Langerhans, precedes elevated blood glucose levels and disease onset. Although several studies have investigated the role of the immune system in this process of insulitis, the importance of the beta cells themselves in the initiation of type 1 diabetes is less well understood. The aim of this study was to investigate intrinsic differences present in the islets from diabetes-prone NOD mice before the onset of insulitis...
January 12, 2017: Diabetologia
https://www.readbyqxmd.com/read/28078221/testosterone-replacement-therapy-and-voiding-dysfunction
#13
REVIEW
Wesley Baas, Tobias S Köhler
Testosterone replacement therapy (TRT) represents an increasing popular treatment option for men with late-onset hypogonadism (LOH). Because of unsubstantiated beliefs of testosterone's effect on the prostate, the FDA has recently placed a warning on testosterone products, stating that TRT may worsen benign prostatic hyperplasia (BPH). Within this review article we have demonstrated the current understanding of the physiology of testosterone and its relationship with prostatic and lower urinary tract physiology...
December 2016: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28074310/recurrence-of-lower-urinary-tract-symptoms-following-prostate-artery-embolization-for-benign-hyperplasia-single-center-experience-comparing-two-techniques
#14
Francisco Cesar Carnevale, Airton Mota Moreira, Sardis Honoria Harward, Shivank Bhatia, Andre Moreira de Assis, Miguel Srougi, Giovanni Guido Cerri, Alberto Azoubel Antunes
PURPOSE: To compare recurrence of lower urinary tract symptoms (LUTS) recurrence at 12 months following original prostate artery embolization (oPAE) or "proximal embolization first, then embolize distal" (PErFecTED) PAE for benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: 105 consecutive patients older than 45 years, with prostate size greater than 30 cm(3), International Prostate Symptom Score (IPSS) ≥ 8, quality of life (QoL) index ≥ 3, and refractory status or intolerance of medical management were prospectively enrolled between June 2008 and August 2013...
January 10, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28073286/bipolar-plasmakinetic-enucleo-resection-of-the-prostate-our-exp%C3%A3-rience-with-245-patients-for-3-years-of-follow-up
#15
Ahmed Abou-Taleb, Waleed El-Shaer, Wael Saber, Tarek Gharib, Alaa Elshaer
OBJECTIVE: the aim of this study was to evaluate the safety, feasibility and effectiveness of bipolar transurethral plasmakinetic enucleation of the prostate (PKEP). PATIENTS AND METHOD: Between January 2010 and October 2013, 245 patients with lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) underwent transurethral enucleation of prostate using bipolar plasma vaporization energy. They were evaluated pre-operatively by Full detailed history, examination especially digital rectal examination (DRE), routine pre-operative investigation, serum prostate-specific antigen (PSA), abdominal and trans-rectal ultrasonography (US) and Maximum flow rates (Qmax)...
January 10, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28073189/relationship-between-lower-urinary-tract-symptoms-and-inguinal-hernia
#16
Aykut Buğra Sentürk, Musa Ekici, Ibrahim Tayfun Sahiner, Tuncay Tas, Basri Cakiroglu
AIM: To determine the relationship between inguinal hernia (and inguinal hernia subtypes) and low urinary tract symptoms (LUTS) due to benign prostate hyperplasia (BPH), that could be more common than we think. METHOD: The study was designed retrospectively and was done in accordance with the principles of the Declaration of Helsinki, including 100 patients aged > 50 years that were divided into 2 groups: patients with BPH (BPH group) and patients with BPH and inguinal hernia (BPH-IH group 2)...
December 30, 2016: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28072862/efficacy-and-safety-of-initial-combination-treatment-of-an-alpha-blocker-with-an-anticholinergic-medication-in-benign-prostatic-hyperplasia-patients-with-lower-urinary-tract-symptoms-updated-meta-analysis
#17
Hyun Jung Kim, Hwa Yeon Sun, Hoon Choi, Jae Young Park, Jae Hyun Bae, Seung Whan Doo, Won Jae Yang, Yun Seob Song, Young Myoung Ko, Jae Heon Kim
BACKGROUND: There is still controversy as to whether initial combination treatment is superior to serial addition of anticholinergics after maintenance or induction of alpha blockers in benign prostatic hyperplasia (BPH)/lower urinary tract symptoms (LUTS). OBJECTIVE: The objective of this study was to determine the benefits and safety of initial combination treatment of an alpha blocker with anticholinergic medication in BPH/LUTS through a systematic review and meta-analysis...
2017: PloS One
https://www.readbyqxmd.com/read/28057997/male-urethral-diverticulum-uncommon-entity-our-experience
#18
Naveen Thakur, Vilas Pandurang Sabale, Deepak Mane, Abhirudra Mullay
Out pouching of the urethral wall could be congenital or acquired. Male urethral diverticulum (UD) is a rare entity. We present 2 cases of acquired and 1 case of congenital male UD. Case 1A: 40 year male presented with SPC and dribbling urine. Clinically he had hard perineal swelling. RGU revealed large diverticulum in proximal bulbar, irregular narrow distal urethra and stricture just beyond diverticulum. Managed with perineal exploration, stone removal, diverticulum repair and urethroplasty using excess diverticular wall...
October 2016: Urology Annals
https://www.readbyqxmd.com/read/28053950/lower-urinary-tract-symptoms-prevalence-perceptions-and-healthcare-seeking-behavior-amongst-nigerian-men
#19
Rufus Wale Ojewola, Ezekiel Sofela Oridota, Olanrewaju Samuel Balogun, Ezra Olatunde Ogundare, Taiwo Opeyemi Alabi
PURPOSE: The aim of this study was to determine the prevalence of lower urinary tract symptoms (LUTS) and the factors influencing the healthcare-seeking behavior of men with LUTS. MATERIALS AND METHODS: A cross-sectional survey was performed of 658 men selected using multi-staged sampling techniques. They were interviewed about LUTS and their healthcare-seeking behavior. The data were analysed using PASW Statistics ver. 18. Associations between specific factors and healthcare-seeking behavior were examined using the chi-square and Fisher exact tests...
December 2016: World Journal of Men's Health
https://www.readbyqxmd.com/read/28053897/effects-of-a-supplement-combining-pycnogenol-%C3%A2-and-l-arginine-aspartate-on-lower-urinary-dysfunction-compared-with-saw-palmetto-extract
#20
Hiroshi Yagi, Ryo Sato, Kojiro Nishio, Gaku Arai, Shigehiro Soh, Hiroshi Okada
OBJECTIVES: Lower urinary tract symptoms (LUTS) and sexual dysfunction (SDys) are common problems that affect quality of life (QOL) in elderly men. In addition to prescribed drugs, many over-the-counter medications including supplements are used to treat QOL diseases. Phosphodiesterase inhibitors are reported to be effective for both LUTS and SDys by increasing nitric oxide levels. French maritime pine bark extract Pycnogenol(®), which is a potent nitric oxide donor, is reported to be effective for SDys...
January 2017: Journal of Traditional and Complementary Medicine
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