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Estrus cycle

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https://www.readbyqxmd.com/read/28507407/study-on-postpartum-estrus-of-guinea-pigs-cavia-cobaya-using-anredera-cordifolia-leaf-extract
#1
D Wijayanti, E T Setiatin, E Kurnianto
AIM: The purpose of this study was to determine the postpartum estrus cycle of guinea pigs (Cavia cobaya) using Anredera cordifolia leaf extract. MATERIALS AND METHODS: Materials used were 8 males and 8 females of C. cobaya with body weight ranged 400-450 g. Mating ratio applied was 1:1. Treatments given were 0, 10, 50 and 90 mg of A. cordifolia leaf extract/head, designated as T0, T1, T2 and T3, respectively. Two females were subjected for each treatment. A. cordifolia leaf extract was administered orally from 10 days prepartum to 10 days postpartum...
April 2017: Veterinary World
https://www.readbyqxmd.com/read/28480612/pharmacological-and-toxicological-study-of-maytenus-ilicifolia-leaf-extract-part-i-preclinical-studies
#2
Ricardo Tabach, Joaquim M Duarte-Almeida, Elisaldo A Carlini
One of the Brazilians medicinal plants most cited in ethnopharmacological surveys for the treatment of ulcers and gastric diseases was evaluated for its efficacy and toxicity. Maytenus ilicifolia leaf extract (MIE) was acutely and chronically (180 days) administered to rats, mice, and dogs. Acute tests were antiulcer effect and toxicological trials (observational pharmacological screening, LD50, motor coordination, sleeping time and motor activity). Chronic tests were the following: weight gain/loss and behavioral parameters in rats and mice; estrus cycle, effects on fertility, and teratogenic studies in rats and mutagenic features in mice, in addition to the Ames and micronucleus test...
May 8, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28462131/effect-of-combination-of-withania-somnifera-dunal-and-tribulus-terrestris-linn-on-letrozole-induced-polycystic-ovarian-syndrome-in-rats
#3
Amrin Saiyed, Nasreen Jahan, Shaikh Ajij Ahmed Makbul, Mushir Ansari, Humaira Bano, Syeda Hajera Habib
BACKGROUND: To investigate the effect of the combination of hydroalcoholic extract of Withania somnifera (WS) and Tribulus terrestris (TT) on letrozole induced polycystic ovarian syndrome (PCOS) in rat. METHODS: Twenty four female Wistar rats of regular estrus cycle were divided into four groups of six animals each. The negative control group received 1 mL of 0.5% carboxy methyl cellulose. The animals of the other groups were treated with letrozole (1 mg/kg) for 21 days for induction of PCOS...
December 2016: Integr Med Res
https://www.readbyqxmd.com/read/28460672/two-dimensional-sonographic-and-doppler-changes-in-the-uteri-of-bitches-according-to-breed-estrus-cycle-phase-parity-and-fertility
#4
Luana Azevedo Freitas, Gustavo Lobato Mota, Herlon Victor Rodrigues Silva, Lúcia Daniel Machado Silva
This study aimed to evaluate the two-dimensional and Doppler ultrasonographic features of bitches' uteri according to breed, cycle phase, parity and fertility during the follicular and early diestrus phases. Thirty-nine pubertal bitches were divided into groups according to breed, parity, and fertility. Sonographic assessments started from the first day of vaginal bleeding and were performed weekly for a month. The diameter of the uterine body was measured longitudinally and the uterine characteristics observed sonographically were evaluated...
June 2017: Theriogenology
https://www.readbyqxmd.com/read/28458884/urinary-profiles-of-progestin-and-androgen-metabolites-in-female-polar-bears-during-parturient-and-non-parturient-cycles
#5
Katrina K Knott, Gabriela F Mastromonaco, Megan A Owen, Andrew J Kouba
Due to the environmental and anthropogenic impacts that continue to threaten the reproductive success of polar bears, a more detailed understanding of their reproductive cycle is needed. Captive populations of polar bears provide an excellent opportunity to learn more about the reproductive physiology of the species. Progestin (P4) and androgen (T) metabolites in urine, and their ratio (P4:T), were examined during 11 reproductive cycles of captive female polar bears (n = 4) to characterize the steroid hormone profile during pregnancy and determine possible variations related to reproductive failure...
2017: Conservation Physiology
https://www.readbyqxmd.com/read/28458454/influence-of-the-estrus-cycle-on-the-evaluation-of-a-vaginal-irritation-study-in-intact-and-ovariectomized-rats
#6
Aiko Ishii, Bunichiro Ogawa, Tomoko Koyama, Yutaka Nakanishi, Minoru Sasaki
When conducting vaginal irritation studies, ovariectomized rats or rabbits are typically used according to practical reports. In the present study, we evaluated the influence of the estrus cycle in a vaginal irritation study using intact rats and ovariectomized rats, which exhibit a late diestrus-like condition, to determine whether intact rats can be useful for evaluating vaginal irritancy. Rats were divided into 4 groups: proestrus, estrus, and metestrus or diestrus in intact rats and ovariectomized rats...
April 2017: Journal of Toxicologic Pathology
https://www.readbyqxmd.com/read/28451590/molecular-signaling-of-progesterone-growth-hormone-wnt-and-her-in-mammary-glands-of-dogs-rodents-and-humans-new-treatment-target-identification
#7
REVIEW
Elpetra P M Timmermans-Sprang, Ana Gracanin, Jan A Mol
Mammary tumors are the most common form of neoplasia in the bitch. Female dogs are protected when they are spayed before the first estrus cycle, but this effect readily disappears and is already absent when dogs are spayed after the second heat. As the ovaries are removed during spaying, ovarian steroids are assumed to play an essential role in tumor development. The sensitivity toward tumor development is already present during early life, which may be caused by early mutations in stem cells during the first estrus cycles...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28447195/salivary-mir-16-mir-191-and-mir-223-intuitive-indicators-of-dominant-ovarian-follicles-in-buffaloes
#8
Prashant Singh, Naresh Golla, Pankaj Singh, Vijay Simha Baddela, Subhash Chand, Rubina Kumari Baithalu, Dheer Singh, Suneel Kumar Onteru
Estrus or sexual receptivity determination is utmost important for efficient breeding programs for female buffaloes. Prominent estrus behavioral symptoms are the result of several molecular and neuroendocrine events involving the ovary and the brain. Expression of estrus behavior is poor in buffaloes during the summer season. Hence, the discovery of biomarkers specific to the estrus stage or its related ovarian events, like the presence of dominant ovarian follicle, is helpful for developing an easy estrus determination method...
April 26, 2017: Molecular Genetics and Genomics: MGG
https://www.readbyqxmd.com/read/28438170/immunolocalization-of-steroidogenic-enzymes-in-the-vaginal-mucous-of-galea-spixii-during-the-estrous-cycle
#9
Amilton Cesar Dos Santos, Alan James Conley, Moacir Franco de Oliveira, Gleidson Benevides Oliveira, Diego Carvalho Viana, Antônio Chaves de Assis Neto
BACKGROUND: The synthesis of sex steroids is controlled by several enzymes such as17α-hydroxylase cytochrome P450 (P450c17) catalyzing androgen synthesis and aromatase cytochrome P450 (P450arom) catalyzing estrogen synthesis, both of which must complex with the redox partner NADPH-cytochrome P450 oxidoreductase (CPR) for activity. Previous studies have identified expression of steroidogenic enzymes in vaginal tissue, suggesting local sex steroid synthesis. The current studies investigate P450c17, P450aromatase and CPR expression in vaginal mucosa of Galea spixii (Spix cavy) by immuno-histochemical and western immunoblot analyses...
April 24, 2017: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/28434750/integrating-an-automated-activity-monitor-into-an-artificial-insemination-program-and-the-associated-risk-factors-affecting-reproductive-performance-of-dairy-cows
#10
Tracy A Burnett, Augusto M L Madureira, Bruna F Silper, A C C Fernandes, Ronaldo L A Cerri
The aim of this study was to compare 2 reproductive programs for the management of first postpartum artificial insemination (AI) based on activity monitors and timed AI, as well as to determine the effect of health-related factors on detection and expression of estrus. Lactating Holstein cows (n = 918) from 2 commercial farms were enrolled. Estrous cycles of all cows were presynchronized with 2 injections of PGF2α administered 2 wk apart. Treatments were (1) first insemination performed by timed AI (TAI) and (2) first insemination based upon the detection of estrus by activity monitors (ACT; Heatime, SCR Engineering, Netanya, Israel) after the presynchronization, whereas cows not inseminated by the detection of estrus were enrolled in the Ovsynch protocol...
April 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28426261/a-morphological-study-of-uterine-alterations-in-mice-due-to-exposure-to-cadmium
#11
M Sapmaz-Metin, Y Topcu-Tarladacalisir, I Kurt-Omurlu, B Karaoz Weller, S Unsal-Atan
We investigated the morphologic and molecular effects of exposure to cadmium (Cd) for 30 and 60 days on the uteri of mice. We assessed uterine morphometric measurements, eosinophilia, mast cell numbers, endometrial apoptosis, proliferation and estrogen receptor alpha (ERα) immunoreactivity. We examined vaginal smears that reflected the hormonal alterations in the female reproductive tract. Because the female reproductive tract exhibits different morphology at each stage of the estrous cycle, we sacrificed all animals at estrus to make appropriate comparisons...
April 20, 2017: Biotechnic & Histochemistry: Official Publication of the Biological Stain Commission
https://www.readbyqxmd.com/read/28416813/brain-derived-neurotrophic-factor-val-66-met-genotype-and-ovarian-steroids-interactively-modulate-working-memory-related-hippocampal-function-in-women-a-multimodal-neuroimaging-study
#12
S-M Wei, E B Baller, P D Kohn, J S Kippenhan, B Kolachana, S J Soldin, D R Rubinow, P J Schmidt, K F Berman
Preclinical evidence suggests that the actions of ovarian steroid hormones and brain-derived neurotrophic factor (BDNF) are highly convergent on brain function. Studies in humanized mice document an interaction between estrus cycle-related changes in estradiol secretion and BDNF Val(66)Met genotype on measures of hippocampal function and anxiety-like behavior. We believe our multimodal imaging data provide the first demonstration in women that the effects of the BDNF Val/Met polymorphism on hippocampal function are selectively modulated by estradiol...
April 18, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28408299/ovarian-hormones-modify-anxiety-behavior-and-glucocorticoid-receptors-after-chronic-social-isolation-stress
#13
Dinah L Ramos-Ortolaza, Raura J Doreste-Mendez, John K Alvarado-Torres, Annelyn Torres-Reveron
Chronic social isolation could lead to a disruption in the Hypothalamic-Pituitary-Adrenal (HPA) axis, resulting in anxiety and depressive-like behaviors but cycling estrogens could modify these behaviors. The aim of this study was to determine if changes in ovarian hormones during the normal cycle could interact with social isolation to alter anxiety and depressive-like behaviors. In parallel, we examined the expression of glucocorticoid receptor (GR) and synaptic vesicle protein synaptophysin in the hippocampus and hypothalamus of Sprague Dawley normal cycling female rats...
April 10, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28407864/birth-of-cloned-mice-from-vaginal-smear-cells-after-somatic-cell-nuclear-transfer
#14
Hiroki Kuwayama, Yoshiaki Tanabe, Teruhiko Wakayama, Satoshi Kishigami
Less invasive methods for donor cell collection will facilitate reproduction of wild animals using somatic-cell nuclear transfer. Stages of the estrous cycle in mice have long been studies using somatic cells that can be collected from vaginal walls using cotton tipped swabs in a relatively non-invasive manner. In this study, we examined the feasibility of these cells as sources of nuclei for somatic-cell cloning using nuclear transfer. Estrous cycles generally comprise proestrus, estrus, metestrus, and diestrus stages...
May 2017: Theriogenology
https://www.readbyqxmd.com/read/28398618/fertility-and-embryo-fetal-development-assessment-in-rats-and-rabbits-with-evacetrapib-a-cholesteryl-ester-transfer-protein-inhibitor
#15
William J Breslin, Kim G Hilbish, Ellen A Cannady, Tammy L Edwards
BACKGROUND: The purpose of these studies was to evaluate the effects of evacetrapib on male and female fertility and on embryo-fetal development (EFD). METHODS: Evacetrapib, a potent and selective inhibitor of cholesteryl ester transfer protein (CETP), was administered daily by oral gavage starting 2 weeks (for female) or 4 weeks (for male) before mating, during cohabitation, and until necropsy in the male rat fertility study or through gestation day (GD) 17 in the female rat combined fertility/EFD study...
April 17, 2017: Birth Defects Res
https://www.readbyqxmd.com/read/28359918/the-effects-of-desipramine-fluoxetine-or-tianeptine-on-changes-in-bulbar-bdnf-levels-induced-by-chronic-social-instability-stress-and-inflammation
#16
Marta M Nowacka-Chmielewska, Daniela Kasprowska, Monika Paul-Samojedny, Anna M Bielecka-Wajdman, Jarosław J Barski, Andrzej Małecki, Ewa Obuchowicz
BACKGROUND: Stress is a major predisposing factor in the development of psychiatric disorders and potential source of augmented inflammatory processes in the brain. Increasing body of evidence shows an important role of alterations in the olfactory bulbs (OBs) function in stress-related disorders. The aim of the present study was to investigate the impact of antidepressants on the alterations of brain-derived neurotrophic factor (BDNF) induced by lipopolysaccharide (LPS) in female rats subjected to chronic social instability stress (CSIS)...
June 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28336267/association-analysis-of-polymorphism-in-kiss1-gene-with-reproductive-traits-in-goats
#17
Mahmoud S El-Tarabany, Asmaa W Zaglool, Akram A El-Tarabany, Ashraf Awad
Understanding the genetic information of related genes is helpful for the selection and breeding course through marker assisted selection. The aim of the current study was to detect polymorphisms of the KiSS1 gene in 137 animals, including Baladi, Zaraibi and Damascus goat breeds by PCR-RFLP, and DNA sequencing and to investigate the association between these variants and reproductive traits. Comparison of the nucleotide sequence indicated the substitution of T with A at position 121 (T121A) in the intron 1 of the KiSS1 gene in all goat breeds...
March 18, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28330768/estrous-detection-by-monitoring-ventral-tail-base-surface-temperature-using-a-wearable-wireless-sensor-in-cattle
#18
Ryotaro Miura, Koji Yoshioka, Toru Miyamoto, Hirofumi Nogami, Hironao Okada, Toshihiro Itoh
In the present study, the ventral tail base surface temperature (ST) was monitored using a wearable wireless sensor for estrus detection in cattle. Relationships among ST, behavioral estrus expression, ovulation, and changes in hormone profiles during the estrous cycle were examined. Holstein Friesian or Japanese Black female cattle were used in summer (August-September), autumn (October-November) and winter (January-February; three animals per season). On Day 11 of the estrous cycle (Day 0=the day of ovulation), the sensor was attached to the surface of the ventral tail base and ST was measured every 2min until Day 11 of the next estrous cycle...
March 11, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28326570/reproductive-disorders-in-female-rats-after-prenatal-exposure-to-betamethasone
#19
Cibele S Borges, Tainá L Pacheco, Marina T Guerra, Aline L Barros, Patricia V Silva, Gabriela Missassi, Katiussia Pinho da Silva, Janete A Anselmo-Franci, André S Pupo, Wilma De G Kempinas
Betamethasone is the drug of choice for antenatal treatment, promoting fetal lung maturation and decreasing mortality. Previous studies in rats reported male programming and alteration in sperm parameters and sexual behavior following intrauterine betamethasone exposure. The impact on the female reproductive development is not known. In this study, rat female offspring was assessed for sexual development, morphophysiology of the reproductive tract and fertility after maternal exposure to 0.1 mg kg(-1) of betamethasone or vehicle on gestational days 12, 13, 18 and 19...
March 21, 2017: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/28321005/the-concentration-dependent-effect-of-progesterone-on-follicle-growth-in-the-mouse-ovary
#20
Kouji Komatsu, Satoru Masubuchi
Follicle growth in the mammalian ovary is coordinately controlled by multiple factors to sustain periodic ovulation. In this study, we investigated the role of progesterone on follicle growth in the mouse ovary. As the concentration of progesterone changes during the estrus cycle, we cultured the sliced mouse ovary in a medium containing 10 ng/ml, 100 ng/ml, and 1 μg/ml progesterone. Progesterone promoted the growth of primordial to primary follicles at 100 ng/ml, while it suppressed the growth of secondary follicles at 1 μg/ml...
March 17, 2017: Journal of Reproduction and Development
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