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https://www.readbyqxmd.com/read/28655271/one-year-results-of-a-randomized-controlled-trial-on-radial-extracorporeal-shock-wave-treatment-with-predictors-of-pain-disability-and-return-to-work-in-patients-with-subacromial-pain-syndrome
#1
Elisabeth Kvalvaag, Cecilie Røe, Kaia B Engebretsen, Helene L Soberg, Niels G Juel, Erik Bautz-Holter, Leiv Sandvik, Jens I Brox
BACKGROUND: Radial extracorporeal Shock Wave Therapy (rESWT) is increasingly used to treat patients with subacromial pain syndrome despite conflicting evidence of its effectiveness. Better knowledge regarding prognostic factors may contribute to the improvement in treatment and prognosis for the patients. AIM: The first aim of this study was to evaluate the effect of rESWT in addition to supervised exercises in patients with subacromial pain syndrome after one year...
June 27, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28655208/accuracy-in-identifying-the-source-of-subarachnoid-hemorrhage-in-the-setting-of-multiple-intracranial-aneurysms
#2
Jennifer L Orning, Sophia F Shakur, Ali Alaraj, Mandana Behbahani, Fady T Charbel, Victor A Aletich, Sepideh Amin-Hanjani
BACKGROUND: Subarachnoid hemorrhage cases with multiple cerebral aneurysms frequently demonstrate a hemorrhage pattern that does not definitively delineate the source aneurysm. In these cases, rupture site is ascertained from angiographic features of the aneurysm such as size, morphology, and location. OBJECTIVE: To examine the frequency with which such features lead to misidentification of the ruptured aneurysm. METHODS: : Records of patients who underwent surgical clipping of a ruptured aneurysm at our institution between 2004 and 2014 and had multiple aneurysms were retrospectively reviewed...
June 26, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28655195/positive-autobiographical-memory-retrieval-reduces-temporal-discounting
#3
Karolina M Lempert, Megan E Speer, Mauricio R Delgado, Elizabeth A Phelps
People generally prefer rewards sooner rather than later. This phenomenon, temporal discounting, underlies many societal problems, including addiction and obesity. One way to reduce temporal discounting is to imagine positive future experiences. Since there is overlap in the neural circuitry associated with imagining future experiences and remembering past events, here we investigate whether recalling positive memories can also promote more patient choice. We found that participants were more patient after retrieving positive autobiographical memories, but not when they recalled negative memories...
June 26, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28655194/predicting-indirect-effects-of-predator-prey-interactions
#4
Sarah E Gilman
Predicting the effects of climate change on species and communities remains a pre-eminent challenge for biologists. Critical among this is understanding the indirect effects of climate change, which arise when the direct, physiological effects of climate on one species change the outcome of its interaction with a second species, altering the success of the second species. A diverse array of approaches to predicting indirect effects exists from mechanistic models, which attempt to build-up from physiological changes to ecological consequences, to ecological models that focus solely on the ecological scale...
June 23, 2017: Integrative and Comparative Biology
https://www.readbyqxmd.com/read/28655182/longitudinal-changes-in-mean-and-pulse-pressure-and-all-cause-mortality-data-from-71-629-untreated-normotensive-individuals
#5
Athanase D Protogerou, Charalambos Vlachopoulos, Frederique Thomas, Yi Zhang, Bruno Pannier, Jacques Blacher, Michel E Safar
BACKGROUND: Blood pressure (BP) includes a steady (mean arterial pressure, MAP) and a pulsatile component that independently predict mortality. The association between longitudinal changes in central (c) pulse pressure (PP), brachial (b) PP, MAP, and incident mortality has never been investigated in this context. METHODS: Brachial MAP and PP were measured at 2 routine checkups (1st visit 1992; mean interval, 5.8 ± 2.4 years) in 71,629 individuals, age 16-95 years, none on antihypertensive drugs...
June 26, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28655176/a-systematic-review-and-meta-analysis-of-the-effectiveness-of-nudging-to-increase-fruit-and-vegetable-choice
#6
Valérie J V Broers, Céline De Breucker, Stephan Van den Broucke, Olivier Luminet
Background: Nudging refers to interventions that organize the choice architecture in order to alter people's behaviour in a predictable way without forbidding any options or significantly changing their economic incentives. As a strategy to encourage healthy behaviour, nudging can serve as a complement to health education. However, the empirical evidence regarding the effectiveness of nudging as a way to influence food choice remains contradictory. To address this issue, a systematic review and meta-analysis was conducted to test the effects of nudging to encourage people to select more fruit and vegetables...
June 25, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28655158/coretracker-accurate-codon-reassignment-prediction-applied-to-mitochondrial-genomes
#7
Noutahi Emmanuel, Calderon Virginie, Blanchette Mathieu, Lang B Franz, El-Mabrouk Nadia
Motivation: Codon reassignments have been reported across all domains of life. With the increasing number of sequenced genomes, the development of systematic approaches for genetic code detection is essential for accurate downstream analyses. Three automated prediction tools exist so far: FACIL, GenDecoder and Bagheera; the last two respectively restricted to metazoan mitochondrial genomes and CUG reassignments in yeast nuclear genomes. These tools can only analyze a single genome at a time and are often not followed by a validation procedure, resulting in a high rate of false positives...
June 26, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28655157/neuroinflammation-and-tau-interact-with-amyloid-in-predicting-sleep-problems-in-aging-independently-of-atrophy
#8
Anders Martin Fjell, Ane-Victoria Idland, Roser Sala-Llonch, Leiv Otto Watne, Tom Borza, Anne Brækhus, Tarjei Lona, Henrik Zetterberg, Kaj Blennow, Torgeir Bruun Wyller, Kristine Beate Walhovd
Sleep problems relate to brain changes in aging and disease, but the mechanisms are unknown. Studies suggest a relationship between β-amyloid (Aβ) accumulation and sleep, which is likely augmented by interactions with multiple variables. Here, we tested how different cerebrospinal fluid (CSF) biomarkers for brain pathophysiology, brain atrophy, memory function, and depressive symptoms predicted self-reported sleep patterns in 91 cognitively healthy older adults over a 3-year period. The results showed that CSF levels of total- and phosphorylated (P) tau, and YKL-40-a marker of neuroinflammation/astroglial activation-predicted poor sleep in Aβ positive older adults...
June 26, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28655154/risk-model-for-deaths-and-renal-replacement-therapy-dependence-in-patients-with-acute-kidney-injury-after-cardiac-surgery
#9
Shiren Sun, Feng Ma, Qiaoneng Li, Ming Bai, Yangping Li, Yan Yu, Chen Huang, Hanmin Wang, Xiaoxuan Ning
OBJECTIVES: Acute kidney injury (AKI) is a serious complication after cardiac surgery and is associated with increased in-hospital deaths. Renal replacement therapy (RRT) is becoming a routine strategy for severe AKI. Our goal was to evaluate the risk factors for death and RRT dependence in patients with AKI after cardiac surgery. METHODS: We included 190 eligible adult patients who had AKI following cardiac surgery and who required RRT at our centre from November 2010 to March 2015...
June 23, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28655152/faulty-adaptation-to-repeated-face-name-associative-pairs-in-mild-cognitive-impairment-is-predictive-of-cognitive-decline
#10
Sarah M Jurick, Gali H Weissberger, Lindsay R Clark, Christina E Wierenga, Yu-Ling Chang, Dawn M Schiehser, S Duke Han, Amy J Jak, Sheena I Dev, Mark W Bondi
Objective: We examined BOLD (Blood-Oxygen-Level Dependent) activity reduction upon stimuli repetition of face-name pairs in older adults with amnestic (aMCI) and non-amnestic (naMCI) mild cognitive impairment diagnosed using a comprehensive actuarial method, and relationships between activity reduction and behavioral indices. Method: Twenty-nine cognitively healthy older adults (CHs) and 20 with MCI (n = 12 aMCI; n = 8 naMCI) underwent functional MRI event-related imaging, a comprehensive neuropsychological battery, and 1-year follow-up exam...
June 26, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28655137/alzheimer-s-disease-genetics-and-abca7-splicing
#11
Jared B Vasquez, James F Simpson, Ryan Harpole, Steven Estus
Both common and rare polymorphisms within ABCA7 have been associated with Alzheimer's disease (AD). In particular, the rare AD associated polymorphism rs200538373 was associated with altered ABCA7 exon 41 splicing and an AD risk odds ratio of ∼1.9. To probe the role of this polymorphism in ABCA7 splicing, we used minigene studies and qPCR of human brain RNA. We report aberrant ABCA7 exon 41 splicing in the brain of a carrier of the rs200538373 minor C allele. Moreover, minigene studies show that rs200538373 acts as a robust functional variant in vitro...
June 22, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28655116/phytotoxic-effects-of-terrestrial-dissolved-organic-matter-on-a-freshwater-cyanobacteria-and-green-algae-species-is-affected-by-plant-source-and-dom-chemical-composition
#12
Amanda D Neilen, Darryl W Hawker, Katherine R O'Brien, Michele A Burford
Here we link plant source phylogeny to its chemical characteristics and determine parameters useful for predicting DOM phytotoxicity towards algal monocultures. We found that DOM characterised using UV-visible spectroscopic indices and elemental analysis is useful for distinguishing DOM plant sources. Specifically, combined values of absorbance at 440 nm and coefficients for the spectral slope ratio, were used to distinguish between gymnosperm-leached DOM and that from angiosperms. In our bioassays, DOM leached from 4 g leaf L(-1) resulted in over 40% inhibition of photosynthetic yield for the cyanobacterium, Cylindrospermopsis raciborskii, for eight of the nine plants tested...
June 17, 2017: Chemosphere
https://www.readbyqxmd.com/read/28655089/-prognostic-value-of-the-revised-international-staging-system-for-newly-diagnosed-multiple-myeloma-patients
#13
J Lu, J Du, W J Fu, H Y He, L Li, R Li, L L Zhou, H Jiang, J Hou
Objective: To assess the prognostic value of revised international staging system (R-ISS) for multiple myeloma (MM) in real world. Methods: A total of 202 newly diagnosis symptomatic MM patients were enrolled from May 2010 to April 2015 and the clinical data were retrospectively analyzed. All the patients received at least four courses of bortezomib-based or thalidomide-based induction therapy. Results: With a median follow-up of 31 months, the cohort included 56 cases in R-ISSⅠ, 108 in R-ISS Ⅱ, and 38 in R-ISS Ⅲ, and the median OS was not reached/61/38 months, respectively (P=0...
June 14, 2017: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://www.readbyqxmd.com/read/28655044/identification-and-remediation-of-phonological-and-motor-errors-in-acquired-sound-production-impairment
#14
Adam Buchwald, Bernadine Gagnon, Michele Miozzo
Purpose: This study aimed to test whether an approach to distinguishing errors arising in phonological processing from those arising in motor planning also predicts the extent to which repetition-based training can lead to improved production of difficult sound sequences. Method: Four individuals with acquired speech production impairment who produced consonant cluster errors involving deletion were examined using a repetition task. We compared the acoustic details of productions with deletion errors in target consonant clusters to singleton consonants...
June 22, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28655042/a-novel-investigation-of-generalized-motor-program-theory-syllable-stress-as-a-motor-class-variable
#15
Kimberly M Meigh
Purpose: This experiment evaluated syllable-stress position as a motor class directed by a syllable-sized generalized motor program. Reaction times were predicted to be slower for stimuli with untrained stress patterns outside the trained motor class. Furthermore, reaction times were predicted to be stable for untrained stimuli within the same motor class regardless of phonetic similarity. Method: Twenty-three young adults with typical speech and hearing participated in a motor-learning study comprised of motor-class training and a judgment task...
June 22, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28654963/visualizing-fmri-bold-responses-to-diverse-naturalistic-scenes-using-retinotopic-projection
#16
Karl Zipser
To view brain activity in register with visual stimuli, a technique here referred to as "retinotopic projection," which translates functional measurements into retinotopic space, is employed. Retinotopic projection is here first applied to a previously acquired fMRI dataset in which a large set of grayscale photos of real scenes were presented to three subjects. A simple model of local contrast integration accounts for much of the data in early visual areas (V1 and V2). However, consistent discrepancies were discovered: Human faces tend to evoke stronger responses relative to other scene elements than predicted by the model, whereas periodic patterns evoke weaker responses than predicted by the model...
June 1, 2017: Journal of Vision
https://www.readbyqxmd.com/read/28654961/labeled-lines-for-image-blur-and-contrast
#17
Michael J Morgan
It has been suggested that blur and contrast discrimination thresholds are limited by a common stage of contrast energy transduction, and that this explains the characteristic "dipper" functions found for contrast and blur discrimination. To test this conjecture, thresholds for discriminating increments from decrements in sharpness/blur, and similarly for contrast, were measured using the same chessboard stimuli with the Method of Single Stimuli (Experiment 1). Using a generic human contrast sensitivity function (HCSF) to calculate energy, thresholds were significantly lower for blur than for contrast...
June 1, 2017: Journal of Vision
https://www.readbyqxmd.com/read/28654958/the-impact-of-whole-genome-sequencing-on-the-primary-care-and-outcomes-of-healthy-adult-patients-a-pilot-randomized-trial
#18
Jason L Vassy, Kurt D Christensen, Erica F Schonman, Carrie L Blout, Jill O Robinson, Joel B Krier, Pamela M Diamond, Matthew Lebo, Kalotina Machini, Danielle R Azzariti, Dmitry Dukhovny, David W Bates, Calum A MacRae, Michael F Murray, Heidi L Rehm, Amy L McGuire, Robert C Green
Background: Whole-genome sequencing (WGS) in asymptomatic adults might prevent disease but increase health care use without clinical value. Objective: To describe the effect on clinical care and outcomes of adding WGS to standardized family history assessment in primary care. Design: Pilot randomized trial. (ClinicalTrials.gov: NCT01736566). Setting: Academic primary care practices. Participants: 9 primary care physicians (PCPs) and 100 generally healthy patients recruited at ages 40 to 65 years...
June 27, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28654938/numerical-study-of-bubble-area-evolution-during-acoustic-droplet-vaporization-enhanced-hifu-treatment
#19
Ying Xin, Aili Zhang, Lisa X Xu, J Brian Fowlkes
Acoustic Droplet Vaporization (ADV) has the potential to shorten treatment time of high intensity focused ultrasound (HIFU) while minimizing the possible effects of microbubbles along the propagation path. Distribution of the bubbles formed from the droplets during the treatment is the major factor shaping the therapeutic region. A numerical model was proposed to simulate the bubble area evolution during this treatment. Using a linear acoustic equation to describe the ultrasound field, a threshold range was defined that determines the amount of bubbles vaporized in the treated area...
June 25, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28654937/handheld-in-vivo-reflectance-confocal-microscopy-for-the-diagnosis-of-eyelid-margin-and-conjunctival-tumors
#20
Elisa Cinotti, Aurélie Singer, Bruno Labeille, Damien Grivet, Pietro Rubegni, Catherine Douchet, Frédéric Cambazard, Gilles Thuret, Philippe Gain, Jean Luc Perrot
Importance: The clinical diagnosis of conjunctival and eyelid margin tumors is challenging, and new noninvasive imaging techniques could be valuable in this field. Objective: To assess the diagnostic accuracy of handheld in vivo reflectance confocal microscopy (IVCM) for the diagnosis of eyelid margin and conjunctival tumors. Design: A prospective observational study was conducted at University Hospital of Saint-Etienne from January 2, 2011, to December 31, 2016 (inclusion of patients until December 31, 2015, and follow-up until December 31, 2016)...
June 22, 2017: JAMA Ophthalmology
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