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Posttraumatic osteoarthritis

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https://www.readbyqxmd.com/read/28326407/instability-of-the-proximal-tibiofibular-joint-associated-with-total-knee-arthroplasty
#1
Martin Bédard, Simon Corriveau-Durand
To our knowledge, proximal tibiofibular joint instability has never been reported in a patient with a total knee arthroplasty (TKA). We present the case of a patient with anterolateral proximal tibiofibular joint instability associated with a complex primary TKA. In 2010, a male patient of 47 years was referred for TKA after posttraumatic osteoarthritis. The patient's history includes a fracture of the left lateral tibial plateau in 2008 and removal of osteosynthesis material in 2009. TKA with a lateral metal augment and intramedullary stem was performed in 2010...
September 2016: Arthroplasty Today
https://www.readbyqxmd.com/read/28293302/3-d-computer-modelling-of-malunited-posterior-malleolar-fractures-effect-of-fragment-size-and-offset-on-ankle-stability-contact-pressure-and-pattern
#2
Teresa Alonso-Rasgado, David Jimenez-Cruz, Michael Karski
BACKGROUND: The positioning of the fracture fragment of a posterior malleolus fracture is critical to healing and a successful outcome as malunion of a posterior malleolar fracture, a condition seen in clinical practice, can affect the dynamics of the ankle joint, cause posterolateral rotational subluxation of the talus and ultimately lead to destruction of the joint. Current consensus is to employ anatomic reduction with internal fixation when the fragment size is larger than 25 to 33% of the tibial plafond...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/28255620/spontaneous-radioscapholunate-fusion-after-septic-arthritis-of-the-wrist-a-case-report
#3
S Quadlbauer, Ch Pezzei, J Jurkowitsch, T Keuchel, T Hausner, M Leixnering
Bacterial septic arthritis rarely occurs in the upper extremities. Yet, early diagnosis and treatment is important, as a delay in diagnosis results in pain, impaired hand function, and degenerative joint disease. Radioscapholunate (RSL) arthrodesis is a well-established procedure for treating inflammatory arthritis and osteoarthritis (primary or posttraumatic), primarily to achieve pain relief. The wrist deformity correction offers an alternative option to total wrist arthrodesis. Indications for a RSL arthrodesis are osteoarthritis of the radiolunate and radioscaphoid joint with a concomitant intact midcarpal joint...
March 2, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28249349/revision-of-total-knee-arthroplasties-performed-in-young-active-patients-with-posttraumatic-and-osteoarthritis
#4
Andrew Brian Old, William John Long, W Norman Scott
Rates of total knee arthroplasty (TKA) in younger patients are rising significantly. A recent study performed at our institute illustrated the excellent survivorship of TKAs in patients younger than 55 years at a mean follow-up period of 25 years. This study reports on the 25 knees in this series that required revision surgery. Twenty-five revisions were performed in 24 patients. Indication for revision, clinical outcomes, and radiographs were reviewed at their most recent follow-up. Revisions were performed in 5 cases of infection, 2 cases of fracture/trauma, 17 cases of wear/loosening, and 1 case of instability...
March 1, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/28244282/descriptive-epidemiology-of-patients-undergoing-total-hip-arthroplasty-in-korea-with-focus-on-incidence-of-femoroacetabular-impingement-single-center-study
#5
Woo Yong Lee, Deuk Soo Hwang, Chang Kyun Noh
We analyzed the causes leading to total hip arthroplasty (THA), aimed to clarify the incidence of femoroacetabular impingement (FAI) among the causes, and compared the incidence in Korea with those in other countries. From January 2000 to December 2014, 1,206 hips of 818 patients who underwent primary THA at our institute were reviewed retrospectively in terms of radiographs and electronic charts. The radiographs and radiographic parameters were reviewed and measured by 2 of the authors, who are orthopedic surgeons...
April 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28224442/report-of-the-primary-outcomes-for-gait-mechanics-in-men-of-the-acl-sports-trial-secondary-prevention-with-and-without-perturbation-training-does-not-restore-gait-symmetry-in-men-1-or-2-years-after-acl-reconstruction
#6
Jacob John Capin, Ryan Zarzycki, Amelia Arundale, Kathleen Cummer, Lynn Snyder-Mackler
BACKGROUND: Movement asymmetries during walking are common after anterior cruciate ligament (ACL) injury and reconstruction and may influence the early development of posttraumatic osteoarthritis. Preoperative neuromuscular training (like perturbation training, which is neuromuscular training requiring selective muscle activation in response to surface perturbations) improves gait asymmetries and functional outcomes among people who are ACL-deficient, but the effect of postoperative perturbation training on gait mechanics after ACL reconstruction is unknown...
February 21, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28164623/decreased-synovial-fluid-%C3%AE-melanocyte-stimulating-hormone-%C3%AE-msh-levels-reflect-disease-severity-in-patients-with-posttraumatic-ankle-osteoarthritis
#7
Guangyu Liu, Yunzhen Chen, Guichun Wang, Jianbing Niu
BACKGROUND: α-Melanocyte-stimulating hormone (α-MSH), an endogenous melanocortin peptide, has been demonstrated to have anti-inflammation effects and protect against cartilage damage. Objective In this study, we aimed to investigate whether α-MSH in ankle joint synovial fluid is associated with the disease severity of posttraumatic ankle osteoarthritis (PTAOA). METHODS: 66 PTAOA patients undergoing ankle arthroscopical debridement or ankle joint replacement were enrolled in the study...
August 1, 2016: Clinical Laboratory
https://www.readbyqxmd.com/read/28146402/a-multicenter-study-of-early-anti-inflammatory-treatment-in-patients-with-acute-anterior-cruciate-ligament-tear
#8
Christian Lattermann, Cale A Jacobs, Mary Proffitt Bunnell, Laura J Huston, Lee G Gammon, Darren L Johnson, Emily K Reinke, Janet L Huebner, Virginia B Kraus, Kurt P Spindler
BACKGROUND: It is increasingly recognized that biochemical abnormalities of the joint precede radiographic abnormalities of posttraumatic osteoarthritis (PTOA) by as much as decades. A growing body of evidence strongly suggests that the progression from anterior cruciate ligament (ACL) injury to PTOA is multifactorial, involving the interplay between biomechanical disturbances and biochemical homeostasis of articular cartilage. PURPOSE: The purposes of this randomized study using an acute ACL injury model were to (1) evaluate the natural progression of inflammatory and chondrodegenerative biomarkers, (2) evaluate the relationship between subjective reports of pain and inflammatory and chondrodegenerative biomarkers, and (3) determine if postinjury arthrocentesis and corticosteroid injection offer the ability to alter this biochemical cascade...
February 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28134048/surgical-treatment-for-pipkin-type-iv-femoral-head-fracture
#9
Yi-Hsun Yu, Yung-Heng Hsu, Ying-Chao Chou, I-Chuan Tseng, Chun-Yi Su, Chi-Chung Wu
PURPOSE: Pipkin type IV femoral head (FH) fracture was thought as poor prognosis. There were several surgical approaches and treatments for this difficult fracture. However, there was no one treatment superior to another. We reviewed a serious of patients with Pipkin type IV FH fracture underwent surgery via a modified Gibson approach. METHODS: We reviewed a consecutive series of nine patients with Pipkin type IV FH fracture under surgery via a modified Gibson approach between 2012 and 2013...
January 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28131634/comminuted-intraarticular-fractures-of-the-tibial-plateau-lead-to-posttraumatic-osteoarthritis-of-the-knee-current-treatment-review
#10
REVIEW
Matthias Aurich, Veit Koenig, Gunther Hofmann
Posttraumatic osteoarthritis (PTOA) of the knee is a common complication after intra- and extra-articular fractures. Moreover, PTOA may also be a result of isolated cartilage defects, meniscus resections, and ligament injuries. There are various methods of treatment of knee joint fractures. However, in the final stage of a PTOA, when nonoperative treatment fails, endoprosthetic joint replacement is the method of choice. Primary total knee replacement (TKR) for the treatment for a fracture of the knee joint is a rare indication, even at major treatment centers...
January 25, 2017: Asian Journal of Surgery
https://www.readbyqxmd.com/read/28129516/intra-articular-recombinant-human-proteoglycan-4-mitigates-cartilage-damage-after-destabilization-of-the-medial-meniscus-in-the-yucatan-minipig
#11
Kimberly A Waller, Kaitlyn E Chin, Gregory D Jay, Ling X Zhang, Erin Teeple, Scott McAllister, Gary J Badger, Tannin A Schmidt, Braden C Fleming
BACKGROUND: Lubricin, or proteoglycan 4 (PRG4), is a glycoprotein responsible for joint boundary lubrication. PRG4 has been shown previously to be down-regulated after traumatic joint injury such as a meniscal tear. Preliminary evidence suggests that intra-articular injection of PRG4 after injury will reduce cartilage damage in rat models of surgically induced posttraumatic osteoarthritis. OBJECTIVE: To determine the efficacy of intra-articular injection of full-length recombinant human lubricin (rhPRG4) for reducing cartilage damage after medial meniscal destabilization (DMM) in a preclinical large animal model...
January 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28122002/a-comparison-of-four-year-health-outcomes-following-combat-amputation-and-limb-salvage
#12
Ted Melcer, Jay Walker, Vibha Bhatnagar, Erin Richard, V Franklin Sechriest, Michael Galarneau
Little research has described the long-term health outcomes of patients who had combat-related amputations or leg-threatening injuries. We conducted retrospective analysis of Department of Defense and Department of Veterans Affairs health data for lower extremity combat-injured patients with (1) unilateral amputation within 90 days postinjury (early amputation, n = 440), (2) unilateral amputation more than 90 days postinjury (late amputation, n = 78), or (3) leg-threatening injuries without amputation (limb salvage, n = 107)...
2017: PloS One
https://www.readbyqxmd.com/read/28121220/functional-results-of-hemi-and-total-shoulder-arthroplasty-according-to-diagnosis-and-patient-age-at-surgery
#13
Boris Sowa, Heidi Thierjung, Matthias Bülhoff, Markus Loew, Felix Zeifang, Thomas Bruckner, Patric Raiss
Background and purpose - There is a lack of information on any associations between the functional outcome and age and diagnosis in patients who have undergone shoulder arthroplasty. We therefore evaluated the functional outcome in "young" and "old" patients treated with either hemiarthroplasty (HA) or total shoulder arthroplasty (TSA) with diverse diagnoses. Patients and methods - The functional results of 496 primary shoulder arthroplasties were analyzed using the Constant score (age- and sex-adjusted) and subjective satisfaction...
January 25, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28097228/kappa-opioid-receptor-signaling-protects-cartilage-tissue-against-posttraumatic-degeneration
#14
Ling Wu, Shu Zhang, Ruzanna Shkhyan, Siyoung Lee, Francesca Gullo, Claire D Eliasberg, Frank A Petrigliano, Kai Ba, Jing Wang, Yunfeng Lin, Denis Evseenko
Osteoarthritis is the most common form of arthritis, and pain relief with opioid-like drugs is a commonly used therapeutic for osteoarthritic patients. Recent studies published by our group showed that the kappa opioid receptor (KOR) is highly expressed during human development in joint-forming cells. However, the precise role of this receptor in the skeletal system remains elusive. The main aim of the current study was to investigate the role of KOR signaling in synovial and cartilaginous tissues in pathological conditions...
January 12, 2017: JCI Insight
https://www.readbyqxmd.com/read/28091802/increased-risk-of-revision-reoperation-and-implant-constraint-in-tka-after-multiligament-knee-surgery
#15
Steven I Pancio, Paul L Sousa, Aaron J Krych, Matthew P Abdel, Bruce A Levy, Diane L Dahm, Michael J Stuart
BACKGROUND: The risk of major complications and revision arthroplasty after TKA in patients who previously underwent multiligament knee surgery have been poorly characterized. QUESTIONS/PURPOSES: Is multiligament knee surgery before TKA associated with (1) worse implant survival, (2) increased use of TKA design constraint, (3) a greater risk for major complications, and (4) poorer scores for pain and function compared with similar patients receiving TKA for primary osteoarthritis? METHODS: Fifty-nine TKAs were performed at our institution between 1985 and 2014 in 59 patients (36 men, 23 women; mean age, 53 years) with a history of previous multiligament knee surgery (≥ two ligaments)...
January 13, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28027660/cross-sectional-study-to-assess-the-functional-outcome-of-neglected-bimalleolar-fracture
#16
Rajeev Shukla, Ravi Kant Jain, Shravan Patidar, Nikhil Jain, Pranav Mahajan
INTRODUCTION: Ankle fracture is the most common intra-articular fracture of a weight-bearing joint and accounts for 9% of all fractures. Ankle fractures are classified into 3 subgroups: unimalleolar, bimalleolar, and trimalleolar fractures. Accurate reduction and stable internal fixation is necessary in bimalleolar fractures; otherwise, it may lead to posttraumatic painful restriction of movements or osteoarthritis. The purpose of this study is to assess the functional outcome and results of treatment of neglected bimalleolar fracture...
December 1, 2016: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/27994716/peculiarities-in-ankle-cartilage
#17
REVIEW
Matthew J Kraeutler, Tanyaporn Kaenkumchorn, Cecilia Pascual-Garrido, Markus A Wimmer, Susanna Chubinskaya
Posttraumatic osteoarthritis (PTOA) is the most common form of osteoarthritis (OA) of the ankle joint. PTOA occurs as a result of several factors, including the poor regenerative capacity of hyaline articular cartilage as well as increased contact stresses following trauma. The purpose of this article is to review the epidemiology, pathogenesis, and potential targets for treatment of PTOA in the ankle joint. Previous reviews primarily addressed clinical approaches to ankle PTOA, while the focus of the current article will be specifically on the newly acquired knowledge of the cellular mechanisms that drive PTOA in the ankle joint and means for potential targeted therapeutics that might halt the progression of cartilage degeneration and/or improve the outcome of surgical interventions...
January 2017: Cartilage
https://www.readbyqxmd.com/read/27992638/medial-malleolar-fractures-and-associated-deltoid-ligament-disruptions-current-management-controversies
#18
Nicholas A Kusnezov, Emmanuel D Eisenstein, Nabih Diab, Ahmed M Thabet, Amr Abdelgawad
Operative fixation of medial malleolar fractures, whether isolated or in the setting of bi- or trimalleolar fractures, remains controversial. Increasingly, anatomic reduction and internal fixation is used to treat medial malleolar fractures to avoid long-term sequelae of symptomatic nonunion and posttraumatic osteoarthritis. However, outcomes have not been significantly different between operative and nonoperative cohorts. Repair of associated deltoid ligament disruption is not common because of reportedly poor outcomes...
December 19, 2016: Orthopedics
https://www.readbyqxmd.com/read/27966012/-surface-replacement-of-proximal-interphalangeal-joints-using-capflex-pip
#19
S F Schindele, A Altwegg, S Hensler
OBJECTIVE OF SURGERY: The cementless implantation of the surface replacement CapFlex-PIP enables pain relief, preservation of motion, improves lateral stability and corrects axis deviation in proximal interphalangeal (PIP) joints of patients with primary and secondary PIP osteoarthritis. INDICATIONS: Painful PIP joints as a result of degenerative or posttraumatic osteoarthritis with restriction of motion. Secondary inflammatory destruction of PIP joints in rheumatoid arthritis with low inflammatory activity and good bone conditions...
February 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/27929439/cell-death-in-chondrocytes-osteoblasts-and-osteocytes
#20
REVIEW
Toshihisa Komori
Cell death in skeletal component cells, including chondrocytes, osteoblasts, and osteocytes, plays roles in skeletal development, maintenance, and repair as well as in the pathogenesis of osteoarthritis and osteoporosis. Chondrocyte proliferation, differentiation, and apoptosis are important steps for endochondral ossification. Although the inactivation of P53 and RB is involved in the pathogenesis of osteosarcomas, the deletion of p53 and inactivation of Rb are insufficient to enhance chondrocyte proliferation, indicating the presence of multiple inhibitory mechanisms against sarcomagenesis in chondrocytes...
December 6, 2016: International Journal of Molecular Sciences
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