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Hypertension, analgesia, blood pressure, heart

Joseph M Blankush, Robbie Freeman, Joy McIlvaine, Trung Tran, Stephen Nassani, I Michael Leitman
Modified Early Warning Scores (MEWS) provide real-time vital sign (VS) trending and reduce ICU admissions in post-operative patients. These early warning calculations classically incorporate oxygen saturation, heart rate, respiratory rate, systolic blood pressure, and temperature but have not previously included end-tidal CO2 (EtCO2), more recently identified as an independent predictor of critical illness. These systems may be subject to failure when physiologic data is incorrectly measured, leading to false alarms and increased workload...
October 20, 2016: Journal of Clinical Monitoring and Computing
Wei Gao, Baoyong Sha, Yuan Zhao, Zhe Fan, Lin Liu, Xin Shen
Propofol lipid emulsion (PLE) is a nanosized sedative, and it is used with a combination of salted antalgic prodrug, fentanyl citrate (FC). To illustrate the synergistic effect of mixing, we compared the sedation/analgesia resulting from simultaneous and sequential administration in surgically induced abortion (No. ChiCTR-IPC-15006153). Simultaneous group showed lower bispectral index, blood pressure, and heart rate, when cannula was inserted into the uterus. It also showed less frequency of hypertension, sinus tachycardia, movement, pain at the injection site, and additional FC...
October 6, 2016: Artificial Cells, Nanomedicine, and Biotechnology
Kavitha Jayaram, Moningi Srilata, Dilipkumar Kulkarni, Gopinath Ramachandran
BACKGROUND: Effective management and pain prevention is of great importance to avoid postoperative complications such as hypertension, agitation, and vomiting. All these adverse events may lead to elevation in intracranial pressure and, in turn, unfavorable outcome and prolonged hospital stay. Development of multiple methods of analgesia may contribute to the alleviation of problems due to pain. We tested the effectiveness of bilateral maxillary block with greater and lesser occipital nerve block for providing analgesia to the scalp...
January 2016: Journal of Neurosurgical Anesthesiology
Z Jabiry-Zieniewicz, F A Dabrowski, B Suchońska, R Kowalczyk, E Nowacka, B Kociszewska-Najman, B Pietrzak, P Malkowski, M Wielgos
AIM: Retrospective analysis of the course of pregnancy, labor and mode of anesthesia in women with portal hypertension and esophageal varices induced by portal vein thrombosis. MATERIAL: From 2000 to 2012 seven pregnant were admitted. None had liver transplantation (Ltx), the varicose have been in the 1st stage. Each of them has been consulted by the obstetrician, transplant surgeon and anesthetist. The patient condition during pregnancy, labor and postpartum period was analyzed...
January 2015: Journal of Maternal-fetal & Neonatal Medicine
Ramamani Mariappan, Harinarayanaprabhu Ashokkumar, Balaji Kuppuswamy
BACKGROUND: Clonidine, an α2 agonist, has been used in anesthesia for many years to provide sedation, anxiolysis, analgesia, controlled hypotension, and to provide opioid-sparing anesthesia. Recently, there has been a great interest in using the newer α2 agonist, dexmedetomidine, because of its more selectivity toward α2 adrenoreceptors. We compared the effects of clonidine with dexmedetomidine on anesthetic requirement and recovery from anesthesia. METHODS: Seventy-four patients undergoing major spine surgery were randomly allocated to receive either oral clonidine premedication followed by an intraoperative saline infusion (group A) or placebo premedication followed by dexmedetomidine infusion in the intraoperative period (group B)...
July 2014: Journal of Neurosurgical Anesthesiology
Ercan Gurses, Derviş Berk, Hülya Sungurtekin, Aslı Mete, Simay Serin
BACKGROUND: To investigate possible effects of high thoracic epidural anesthesia (HTEA) on mixed venous oxygen saturation (SvO2) in coronary artery bypass grafting surgery (CABGS) MATERIAL AND METHODS: Sixty-four patients scheduled for CABGS were randomly assigned to either test (HTEA) or control group. Standard balanced general anesthesia was applied in both groups. Mean arterial blood pressure (MAP), heart rate (HR), oxygen saturation (SpO2), central venous pressure (CVP), cardiac output (CO), cardiac index (CI), systemic vascular resistance (SVR), pulmonary vascular resistance (PVR), mean pulmonary arterial pressure (PAP), pulmonary capillary wedge pressure (PCWP), pulmonary compliance (C), bispectral index (BIS), body temperature, SvO2, hematocrit values were recorded before induction...
2013: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Rebecca A Krimins, Jeff C Ko, Ann B Weil, Mark E Payton
OBJECTIVE: To compare anesthetic, analgesic, and cardiorespiratory effects in dogs after IM administration of dexmedetomidine (7.5 μg/kg)-butorphanol (0.15 mg/kg)-tiletamine-zolazepam (3.0 mg/kg; DBTZ) or dexmedetomidine (15.0 μg/kg)-tramadol (3.0 mg/kg)-ketamine (3.0 mg/kg; DTrK) combinations. ANIMALS: 6 healthy adult mixed-breed dogs. PROCEDURES: Each dog received DBTZ and DTrK in a randomized, crossover-design study with a 5-day interval between treatments...
November 2012: American Journal of Veterinary Research
Marimuthu Muthukumar, Virendra K Arya, Preety J Mathew, Ramesh K Sharma
Surgical field infiltration with adrenaline is common practice for quality surgical field during cleft lip and palate repair in children. Intravascular absorption of adrenaline infiltration often leads to adverse haemodynamic responses. In this prospective, double-blinded, randomised study the haemodynamic effects, quality of surgical field and postoperative analgesia following surgical field infiltration with different concentrations of adrenaline with and without lignocaine were compared in 100 American Society of Anesthesiologists physical status I children aged six months to seven years undergoing cleft lip/palate surgery...
January 2012: Anaesthesia and Intensive Care
R Logier, J De Jonckheere, M Delecroix, A Keribedj, M Jeanne, R Jounwaz, B Tavernier
Pneumatic tourniquets are widely used to provide a bloodless operative field during upper or lower limb surgery. If tourniquet inflation during general anesthesia is initially a mild stimulus, a long duration of inflation can imply heart rate and blood pressure increasing. However, heart rate or blood pressure increasing can also be caused by other external stimuli. Indeed, in the case of an insufficient analgesia, painful surgical stimuli can also cause an increase in heart rate and blood pressure. Therefore, in the case of the use of a tourniquet during surgery, it's very difficult for the anesthesiologist to distinguish hypertension caused by pain from hypertension caused by tourniquet inflation...
2011: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Yu Wu, Jun Yuan, Xin-Min Feng
OBJECTIVE: To compare the difference between transcutaneous electrical acupoint stimulation (TEAS) assisted general anesthesia and simple general anesthesia on stress response during laparoscopic cholecystectomy (LC) in aged patients. METHODS: Forty patients underwent LC were randomly divided into a TENS assisted general anesthesia group (group T) and a general anesthesia group (group G), 20 cases in each group. After TEAS for 30 min, general anesthesia was applied in group T, and TEAS was continued until LC over...
February 2011: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Robert Hanss, Berthold Bein
The number of patients with limited organ function is steadily increasing due to the aging of the population. Consequently, a growing number of patients needing surgery is accompanied by serious comorbidities. These patients are at high risk of perioperative organ dysfunction. In this context cardiac events (e.g. cardiac arrhythmias, angina or myocardial infarction) play a major role with significant impact on postoperative care, long term outcome and economic sequelae. Thus, anaesthesiologists must prevent such events in the perioperative period...
April 2010: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
D V Medvedev, A Zh Petrikas
Effectiveness of intraligamentous anesthesia for caries and pulpitis in 83 patients was studied. This was efficient and simple technique of anesthesia of lower lateral teeth. Pulpul analgesia occured almost immediately after the injection and was accompanied by minimum of subjective sensations in the mouth. Arterial pressure and heart rate were investigated in all patients before, immediately and in 15-20 min after the injection with the help of automated monitor. Intraligamentous anesthesia beeng a vascular method caused in hypertensive patients unpredictable arterial pressure elevations...
2009: Stomatologii︠a︡
Bruno Salomé de Morais, Yerkes Pereira Silva, Marcos Guilherme C Cruvinel, Carlos Henrique Viana de Castro, Marco Victor Hermeto
BACKGROUND AND OBJECTIVES: The subarachnoid administration of morphine is a well-established anesthetic technique of postoperative analgesia due to its efficacy safety and low cost. The objective of this paper was to report the accidental subarachnoid administration of 4 mg of morphine complicated by atrial fibrillation after administration of naloxone. CASE REPORT: A 45-year old male patient with 75 kg, 1.72 m, physical status ASA II, hypertensive, was scheduled for reconstruction of the anterior cruciate ligament of the left knee...
March 2008: Revista Brasileira de Anestesiologia
S M Ibrahim, E Mustafa, A Louon
The case is reported of a 30-year-old multigravida, with insignificant history and stable vital signs, admitted to the labour room for normal vaginal delivery of twins. She received combined spinal epidural analgesia (bupivacaine plus fentanyl) for 3 h. Following uneventful delivery she received 0.2 mg methylergonovine maleate, intramuscularly. Nausea and vomiting occurred 70 min after placenta delivery, heart rate decreased, arterial blood pressure increased and there was chest pain. After excluding cardiac ischaemia, 0...
September 2008: Journal of International Medical Research
Hongmei Liu, Yang Yang, Ruihua Xin, Xing Liu, Yiming Cao, Jingman Ni, Rui Wang
Previously, five synthetic peptides derived from endomorphin-1 (Tyr1-Pro2-Trp3-Phe4-NH2, EM-1), including Tyr-D-Ala-Trp-p-Cl-Phe-NH2 (HDAPC), Tyr-D-Ala-Trp-Phe-NH2 (HDADC), Nalpha-amidino-Tyr-D-Ala-Trp-p-Cl-Phe-NH2 (GDAPC), Nalpha-amidino-Tyr-D-Ala-Trp-Phe-NH2 (GDADC) and Nalpha-amidino-Tyr-D-Pro-Gly-Trp-p-Cl-Phe-NH2 (GBDPC), were described to elicit analgesia by subcutaneous administration with enhanced metabolic stabilities. To further our knowledge of the influences of particular modification on the pharmacological activities of EM-1, the present study was undertaken to investigate cardiovascular effects of these peptides in anesthetized rats by intravenous injection...
June 2008: Peptides
R Sümpelmann, A Brauer, S Krohn, D Schröder, J M Strauß
UNLABELLED: Pain and pain-related sympathoadrenergic reactions (hypertension, tachycardia) accompanied by nausea, vomiting and shivering are the most common side effects of recovery from anaesthesia. The alpha(2)agonist clonidine acts as a sedative, anxiolytic, antihypertensive, antiemetic, antisialogogue and decreases the incidence of shivering. Thus, we studied the effects of intraoperatively administered clonidine on the recovery period and the postoperative analgesic requirements in patients undergoing maxillofacial surgery...
March 1994: Der Schmerz
Anja Pohl-Schickinger, Julia Lemmer, Michael Hübler, Vladimir Alexi-Meskishvili, Matthias Redlin, Felix Berger, Brigitte Stiller
BACKGROUND: The aim of this study was to investigate the hemodynamic profile and heart rhythm in infants who were given intravenous clonidine infusion after prolonged analgesia/sedation following cardiac surgery. METHODS: This is a single center retrospective review. A total of 542 cardiovascular surgical procedures in infants aged 0-24 months with congenital heart disease were performed between 01/2003 and 12/2005 at the Deutsches Herzzentrum in Berlin. The majority received no long-term analgesia/sedation, but 50 (9%) of these infants received clonidine (dosed at 0...
March 2008: Paediatric Anaesthesia
Maria E Gómez-Vázquez, Eduardo Hernández-Salazar, Abel Hernández-Jiménez, Arturo Pérez-Sánchez, Vilma A Zepeda-López, Mario Salazar-Páramo
STUDY OBJECTIVES: To determine the analgesic efficacy of dexmedetomidine in the early postoperative period. DESIGN: Randomized, double-blind, double placebo-controlled clinical trial. SETTING: University medical center. PATIENTS: 30 ASA physical status I, II, and III patients with cruciate ligament lesion and joint fibrosis who were scheduled for knee arthroscopy. INTERVENTIONS: Patients were prospectively randomized to receive dexmedetomidine one mcg/kg(-1) intravenously (IV), for 10 minutes followed by dexmedetomidine 0...
December 2007: Journal of Clinical Anesthesia
Muhammet Gozdemir, Huseyin Sert, Nisa Yilmaz, Orhan Kanbak, Burhanettin Usta, Ruveyda Irem Demircioglu
The purpose of this study was to ascertain whether total intravenous anesthesia (TIVA) with propofol and remifentanil differs from inhalational anesthesia with desflurane and nitrous oxide in terms of hemodynamics, recovery profile, and postoperative analgesic demand in patients undergoing elective microsurgical vertebral disk resection. A total of 60 patients were randomly assigned to receive TIVA with propofol and remifentanil or inhalational anesthesia with desflurane and nitrous oxide. The TIVA group (n=30) then received 50%/50% N(2)O/O(2)...
May 2007: Advances in Therapy
Domenic A Sica
Centrally acting agents stimulate alpha(2) receptors and/or imadozoline receptors on adrenergic neurons situated within the rostral ventrolateral medulla and, in so doing, sympathetic outflow is reduced. Centrally acting agents also stimulate peripheral alpha(2) receptors, which, for the most part, is of marginal clinical significance. Central a agonists have had a lengthy history of use, starting with alpha-methyldopa, which has had a dramatic decline in use, in part, because of bothersome side effects. Patients who require multidrug therapy with otherwise resistant hypertension, such as diabetic and/or renal failure patients, are typically responsive to these drugs, as are patients with sympathetically driven forms of hypertension...
May 2007: Journal of Clinical Hypertension
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