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https://www.readbyqxmd.com/read/29323482/a-fluorine-free-slippery-surface-with-hot-water-repellency-and-improved-stability-against-boiling
#1
Ryo Togasawa, Mizuki Tenjimbayashi, Takeshi Matsubayashi, Takeo Moriya, Kengo Manabe, Seimei Shiratori
Inspired by natural living things such as lotus leaves and pitcher plants, researchers have developed many excellent antifouling coatings. In particular, hot-water repellent surfaces have received much attention in recent years because of their wide range of applications. However, coatings with stability against boiling in hot water have not been achieved yet. Long-chain perfluorinated materials, which are often used for liquid-repellent coatings owing to their low surface energy, hinder the potential application of antifouling coatings in food containers...
January 11, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29320996/healthy-apple-program-to-support-child-care-centers-to-alter-nutrition-and-physical-activity-practices-and-improve-child-weight-a-cluster-randomized-trial
#2
Jodi D Stookey, Jane Evans, Curtis Chan, Lisa Tao-Lew, Tito Arana, Susan Arthur
BACKGROUND: North Carolina Nutrition and Physical Activity Self-Assessment for Child Care (NAP SACC) resources improve child body mass index (BMI) when the resources are introduced by nurses to child care providers, and offered with workshops and incentives. In San Francisco, public health and child care agencies partnered to adapt NAP SACC resources into an annual "Healthy Apple" quality improvement program (HAP). METHODS: This cluster randomized controlled trial pilot-tested integration of the HAP with bi-annual public health screenings by nurses...
December 19, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29318169/reasons-for-retirement-following-ulnar-collateral-ligament-reconstruction-among-major-league-baseball-pitchers
#3
Brandon J Erickson, Junyoung Ahn, Peter N Chalmers, Christopher S Ahmad, Bernard R Bach, Nikhil N Verma, Anthony A Romeo
Background: Ulnar collateral ligament reconstruction (UCLR) has become an increasingly common procedure among Major League Baseball (MLB) pitchers. The long-term effects of this procedure on the career of an MLB pitcher are largely unknown. Purpose/Hypothesis: The purpose of this study was to determine why and when MLB pitchers who underwent UCLR during their careers retired from baseball as compared with controls. We hypothesized that pitchers who underwent UCLR are no more likely than control pitchers to retire from elbow or shoulder problems...
December 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29311117/expanded-genomic-profiling-of-circulating-tumor-cells-in-metastatic-breast-cancer-patients-to-assess-biomarker-status-and-biology-over-time
#4
Mark Jesus M Magbanua, Hope S Rugo, Denise M Wolfe, Louai Hauranieh, Ritu Roy, Praveen Pendyala, Eduardo Sosa, Janet H Scott, Jin Sun Lee, Brandelyn N Pitcher, Terry M Hyslop, William T Barry, Steven J Isakoff, Maura N Dickler, Laura J Van't Veer, John W Park
Purpose: We profiled circulating tumor cells (CTCs) patients to study the biology of blood-borne metastasis and to monitor biomarker status in metastatic breast cancer (MBC).Methods: CTCs were isolated from 105 MBC patients using EPCAM-based immunomagnetic enrichment and fluorescence-activated cells sorting (IE/FACs), 28 of whom had serial CTC analysis (74 samples, 2-5 time points). CTCs were subjected to microfluidic-based multiplex QPCR array of 64 cancer-related genes (n=151) and genome-wide copy number analysis by array comparative genomic hybridization (n=49)...
January 8, 2018: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29306397/pentaplacodinium-saltonense-gen-et-sp-nov-dinophyceae-and-its-relationship-to-the-cyst-defined-genus-operculodinium-and-yessotoxin-producing-protoceratium-reticulatum
#5
Kenneth Neil Mertens, M Consuelo Carbonell-Moore, Vera Pospelova, Martin J Head, Andrea Highfield, Declan Schroeder, Haifeng Gu, Karl B Andree, Margarita Fernandez, Aika Yamaguchi, Yoshihito Takano, Kazumi Matsuoka, Elisabeth Nézan, Gwenael Bilien, Yuri Okolodkov, Kazuhiko Koike, Mona Hoppenrath, Maya Pfaff, Grant Pitcher, Abdulrahman Al-Muftah, André Rochon, Po Teen Lim, Chui Pin Leaw, Zhen Fei Lim, Marianne Ellegaard
Strains of a dinoflagellate from the Salton Sea, previously identified as Protoceratium reticulatum and yessotoxin producing, have been reexamined morphologically and genetically and Pentaplacodinium saltonense n. gen. et sp. is erected to accommodate this species. Pentaplacodinium saltonense differs from Protoceratium reticulatum (Claparède et Lachmann 1859) Bütschli 1885 in the number of precingular plates (five vs. six), cingular displacement (two widths vs. one), and distinct cyst morphology. Incubation experiments (excystment and encystment) show that the resting cyst of Pentaplacodinium saltonense is morphologically most similar to the cyst-defined species Operculodinium israelianum (Rossignol, 1962) Wall (1967) and O...
January 2018: Harmful Algae
https://www.readbyqxmd.com/read/29301986/declining-oxygen-in-the-global-ocean-and-coastal-waters
#6
REVIEW
Denise Breitburg, Lisa A Levin, Andreas Oschlies, Marilaure Grégoire, Francisco P Chavez, Daniel J Conley, Véronique Garçon, Denis Gilbert, Dimitri Gutiérrez, Kirsten Isensee, Gil S Jacinto, Karin E Limburg, Ivonne Montes, S W A Naqvi, Grant C Pitcher, Nancy N Rabalais, Michael R Roman, Kenneth A Rose, Brad A Seibel, Maciej Telszewski, Moriaki Yasuhara, Jing Zhang
Oxygen is fundamental to life. Not only is it essential for the survival of individual animals, but it regulates global cycles of major nutrients and carbon. The oxygen content of the open ocean and coastal waters has been declining for at least the past half-century, largely because of human activities that have increased global temperatures and nutrients discharged to coastal waters. These changes have accelerated consumption of oxygen by microbial respiration, reduced solubility of oxygen in water, and reduced the rate of oxygen resupply from the atmosphere to the ocean interior, with a wide range of biological and ecological consequences...
January 5, 2018: Science
https://www.readbyqxmd.com/read/29291284/little-league-shoulder-in-a-15-year-old-male-baseball-pitcher
#7
Mark C Zipser, Jonathan C Sum, Alison G Wilcox
A 15-year-old baseball pitcher presented to physical therapy with a 1-week history of acute right shoulder pain experienced during the acceleration phase of throwing. The week after physical therapy evaluation, the patient returned with radiographs and magnetic resonance imaging results that revealed lateral physeal widening with adjacent edema. Additionally, a nondisplaced labral tear was noted. In this case, imaging was necessary for an accurate diagnosis of lateral physeal widening, commonly referred to as "Little League shoulder...
January 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29289396/assessment-of-elbow-torque-and-other-parameters-during-the-pitching-motion-comparison-of-fastball-curveball-and-change-up
#8
Eric C Makhni, Vincent A Lizzio, Fabien Meta, Jeffrey P Stephens, Kelechi R Okoroha, Vasilios Moutzouros
PURPOSE: To assess the precision of a new wearable device in detecting medial elbow torque during the pitching motion in competitive baseball pitchers and to determine the differences in torque across pitch types and thrower demographic characteristics. METHODS: High school and collegiate baseball pitchers were recruited from August 1, 2016, to January 31, 2017, through direct request by athletic trainers and coaches. Body dimensions and throwing arm measurements of the participants were collected...
December 27, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29286674/a-lubricant-sandwiched-coating-with-long-term-stable-anticorrosion-performance
#9
Mizuki Tenjimbayashi, Sachiko Nishioka, Yuta Kobayashi, Koki Kawase, Jiatu Li, Jyunichiro Abe, Seimei Shiratori
Lubricant-infused surface(s) (LIS) bio-inspired by the Nepenthes pitcher plant are receiving enormous attention owing to their excellent hydrophobicity as well as their self-healing ability. Thus, they have been applied as anticorrosion coatings. However, the loss of lubricant mediated by vapor or other liquids deteriorates their functions. Herein, we introduce a lubricant-inserted (sandwiched) microporous triple-layered surface (LIMITS) that prevents the sudden loss of lubricant. The sandwiched lubricant gradually self-secretes toward the surface, resulting in long-term stability even under water...
December 29, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29283678/pitch-volume-and-glenohumeral-and-hip-motion-and-strength-in-youth-baseball-pitchers
#10
Josie L Harding, Kelsey J Picha, Kellie C Huxel Bliven
CONTEXT:   Increased pitch volume and altered glenohumeral (GH) and hip range of motion (ROM) and strength contribute to injury risk in baseball pitchers. Although these factors affect one another, whether they are related is unknown. OBJECTIVE:   To examine relationships among cumulative and seasonal pitch volume, ROM, and strength of the GH and hip joints in youth baseball pitchers. DESIGN:   Cross-sectional study. SETTING:   Baseball practice facilities...
December 28, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/29245141/a-systematic-review-of-the-state-of-the-literature-on-sexually-exploited-boys-internationally
#11
Melissa Moynihan, Katherine Mitchell, Claire Pitcher, Farinaz Havaei, Max Ferguson, Elizabeth Saewyc
This systematic review assessed the current state of the literature on sexually exploited boys internationally. We aimed to describe what is known about sexual exploitation of boys, identify gaps in the literature, provide implications for practice, and make recommendations for future research. Multiple database searches were conducted using a combination of controlled vocabulary and keywords to capture child and adolescent sexual exploitation. Our search identified 11,099 unique references and excluded studies that did not include male participants less than 18 years old or disaggregate results by relevant age groups and/or by sex...
December 12, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29241660/effects-of-glenohumeral-internal-rotation-deficit-on-baseball-pitching-among-pitchers-of-different-ages
#12
Paul Pei-Hsi Chou, You-Li Chou, Yan-Sheng Wang, Rong-Tyai Wang, Hwai-Ting Lin
BACKGROUND: Previous studies have reported that glenohumeral internal rotation deficit (GIRD) may increase the risk of shoulder injury. However, the effects of GIRD on baseball pitching among pitchers of different age groups are still unclear. METHODS: The study participants were 24 high school and 24 university pitchers. For each age group, the pitchers were evenly divided into a GIRD group and a normal group. The pitching motion of each participant was captured using a motion analysis system at a sampling frequency of 300 Hz...
December 11, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29225021/implications-of-core-and-hip-injuries-on-major-league-baseball-pitchers-on-the-disabled-list
#13
Nathan E Marshall, Toufic R Jildeh, Kelechi R Okoroha, Ankur Patel, Vasilios Moutzouros, Eric C Makhni
PURPOSE: To investigate the frequency of core and hip injuries in Major League Baseball (MLB) pitchers and their impact on performance, workload, and pitch type. METHODS: Demographic, performance data, and injury data were acquired for 330 MLB pitchers with 454 injuries placed on the disabled list (DL) from 2014 to 2015 seasons. Core and hip/groin injuries were analyzed in which injury year data were compared with career data and against other injury groups. RESULTS: Core injuries represented 14% of all injuries and hip/groin injuries represented 7%...
December 7, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29208716/direct-measurements-of-meltwater-runoff-on-the-greenland-ice-sheet-surface
#14
Laurence C Smith, Kang Yang, Lincoln H Pitcher, Brandon T Overstreet, Vena W Chu, Åsa K Rennermalm, Jonathan C Ryan, Matthew G Cooper, Colin J Gleason, Marco Tedesco, Jeyavinoth Jeyaratnam, Dirk van As, Michiel R van den Broeke, Willem Jan van de Berg, Brice Noël, Peter L Langen, Richard I Cullather, Bin Zhao, Michael J Willis, Alun Hubbard, Jason E Box, Brittany A Jenner, Alberto E Behar
Meltwater runoff from the Greenland ice sheet surface influences surface mass balance (SMB), ice dynamics, and global sea level rise, but is estimated with climate models and thus difficult to validate. We present a way to measure ice surface runoff directly, from hourly in situ supraglacial river discharge measurements and simultaneous high-resolution satellite/drone remote sensing of upstream fluvial catchment area. A first 72-h trial for a 63.1-km2 moulin-terminating internally drained catchment (IDC) on Greenland's midelevation (1,207-1,381 m above sea level) ablation zone is compared with melt and runoff simulations from HIRHAM5, MAR3...
December 5, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29192934/predicting-injury-in-professional-baseball-pitchers-from-delivery-mechanics-a-statistical-model-using-quantitative-video-analysis
#15
E Grant Sutter, Justin Orenduff, Will J Fox, Joshua Myers, Grant E Garrigues
Baseball pitching imposes significant stress on the upper extremity and can lead to injury. Many studies have attempted to predict injury through pitching mechanics, most of which have used laboratory setups that are often not practical for population-based analysis. This study sought to predict injury risk in professional baseball pitchers using a statistical model based on video analysis evaluating delivery mechanics in a large population. Career data were collected and video analysis was performed on a random sample of former and current professional pitchers...
November 30, 2017: Orthopedics
https://www.readbyqxmd.com/read/29191666/nepenthes-state-of-the-art-of-an-inspiring-plant-for-biotechnologists
#16
REVIEW
Sissi Miguel, Alain Hehn, Frédéric Bourgaud
Plant carnivory results from the adaptation of plants to their environment. The capture and digestion of preys, followed by their assimilation by the plant is a source of additional nutrients to overcome scarce nutrient in poor soils. Nepenthes are highly studied carnivorous plants and have developed a number of ecological traits which have attracted the attention of plant biologists. Multiple adaptive strategies developed by these plants make them a source of inspiration for many applications ranging from therapeutic treatments to biocontrol solution in agriculture...
November 27, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/29188284/vemurafenib-for-braf-v600-mutant-erdheim-chester-disease-and-langerhans-cell-histiocytosis-analysis-of-data-from-the-histology-independent-phase-2-open-label-ve-basket-study
#17
Eli L Diamond, Vivek Subbiah, A Craig Lockhart, Jean-Yves Blay, Igor Puzanov, Ian Chau, Noopur S Raje, Jurgen Wolf, Joseph P Erinjeri, Jean Torrisi, Mario Lacouture, Elena Elez, Ferran Martínez-Valle, Benjamin Durham, Maria E Arcila, Gary Ulaner, Omar Abdel-Wahab, Bethany Pitcher, Martina Makrutzki, Todd Riehl, José Baselga, David M Hyman
Importance: The histiocytic neoplasms Erdheim-Chester disease (ECD) and Langerhans cell histiocytosis (LCH) are highly enriched for BRAF V600 mutations and have been previously shown to be responsive to treatment with vemurafenib, an inhibitor of the BRAF V600 kinase. However, the long-term efficacy and safety of prolonged vemurafenib use in these patients are not defined. Here we analyze the final efficacy and safety data for vemurafenib in patients with ECD and LCH enrolled in the VE-BASKET study...
November 29, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/29177104/environmental-proteomics-reveals-taxonomic-and-functional-changes-in-an-enriched-aquatic-ecosystem
#18
Amanda C Northrop, Rachel Brooks, Aaron M Ellison, Nicholas J Gotelli, Bryan A Ballif
Aquatic ecosystem enrichment can lead to distinct and irreversible changes to undesirable states. Understanding changes in active microbial community function and composition following organic-matter loading in enriched ecosystems can help identify biomarkers of such state changes. In a field experiment, we enriched replicate aquatic ecosystems in the pitchers of the northern pitcher plant, Sarracenia purpurea. Shotgun metaproteomics using a custom metagenomic database identified proteins, molecular pathways, and contributing microbial taxa that differentiated control ecosystems from those that were enriched...
October 2017: Ecosphere
https://www.readbyqxmd.com/read/29176651/exosomal-cargo-including-microrna-regulates-sensory-neuron-to-macrophage-communication-after-nerve-trauma
#19
Raffaele Simeoli, Karli Montague, Hefin R Jones, Laura Castaldi, David Chambers, Jayne H Kelleher, Valentina Vacca, Thomas Pitcher, John Grist, Hadil Al-Ahdal, Liang-Fong Wong, Mauro Perretti, Johnathan Lai, Peter Mouritzen, Paul Heppenstall, Marzia Malcangio
Following peripheral axon injury, dysregulation of non-coding microRNAs (miRs) occurs in dorsal root ganglia (DRG) sensory neurons. Here we show that DRG neuron cell bodies release extracellular vesicles, including exosomes containing miRs, upon activity. We demonstrate that miR-21-5p is released in the exosomal fraction of cultured DRG following capsaicin activation of TRPV1 receptors. Pure sensory neuron-derived exosomes released by capsaicin are readily phagocytosed by macrophages in which an increase in miR-21-5p expression promotes a pro-inflammatory phenotype...
November 24, 2017: Nature Communications
https://www.readbyqxmd.com/read/29171692/8-mercaptoguanine-derivatives-as-inhibitors-of-dihydropteroate-synthase
#20
James Swarbrick, Matthew Dennis, Michael Lee, Jitendra Harjani, Mohamed Ahmed, Aaron Debono, Noel Pitcher, Zhong-Chang Wang, Sandeep Chhabra, Nicholas Barlow, Raphael Rahmani, Ben Cleary, Olan Dolezal, Meghan Hattarki, Luigi Aurelio, Jeremy Shonberg, Bim Graham, Tom Peat, Jonathan Baell
Dihydropteroate synthase (DHPS) is an enzyme of the folate biosynthesis pathway which catalyzes the formation of 7,8-dihydropteroate (DHPt) from 6-hydroxymethyl-7,8-dihydropterin pyrophosphate (DHPPP) and para-aminobenzoic acid (pABA). DHPS is the long-standing target of the sulfonamide class of antibiotics that compete with pABA. In the wake of sulfa drug resistance, targeting the structurally rigid (and more conserved) pterin site has been proposed as an alternate strategy to inhibit DHPS in wild-type and sulfa drug resistant strains...
November 24, 2017: Chemistry: a European Journal
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