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https://www.readbyqxmd.com/read/28107113/the-relationship-between-pitching-mechanics-and-injury
#1
Peter N Chalmers, Markus A Wimmer, Nikhil N Verma, Brian J Cole, Anthony A Romeo, Gregory L Cvetanovich, Michael L Pearl
CONTEXT: The overhand pitch is one of the fastest known human motions and places enormous forces and torques on the upper extremity. Shoulder and elbow pain and injury are common in high-level pitchers. A large body of research has been conducted to understand the pitching motion. EVIDENCE ACQUISITION: A comprehensive review of the literature was performed to gain a full understanding of all currently available biomechanical and clinical evidence surrounding pitching motion analysis...
January 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28105664/visceral-and-somatic-pain-modalities-reveal-nav-1-7-independent-visceral-nociceptive-pathways
#2
James R F Hockley, Rafael González-Cano, Sheridan McMurray, Miguel A Tejada-Giraldez, Cian McGuire, Antonio Torres, Anna L Wilbrey, Vincent Cibert-Goton, Francisco R Nieto, Thomas Pitcher, Charles H Knowles, José Manuel Baeyens, John N Wood, Wendy J Winchester, David C Bulmer, Cruz Miguel Cendán, Gordon McMurray
Voltage-gated sodium channel NaV 1.7 is required for acute and inflammatory pain in mice and humans but its significance for visceral pain is unknown. Here we examine the role of NaV 1.7 in visceral pain processing and the development of referred hyperalgesia using a conditional nociceptor-specific NaV 1.7 knockout mouse (NaV 1.7(Nav1.8) ) and selective small-molecule NaV 1.7 antagonist PF-5198007. NaV 1.7(Nav1.8) mice showed normal nociceptive behaviours to intracolonic application of either capsaicin or mustard oil, stimuli known to evoke sustained nociceptor activity and sensitization following tissue damage, respectively...
January 20, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28104091/major-league-pitching-workload-after-primary-ulnar-collateral-ligament-reconstruction-and-risk-for-revision-surgery
#3
Robert A Keller, Nima Mehran, Nathan E Marshall, Kelechi R Okoroha, Lafi Khalil, James E Tibone, Vasilios Moutzouros
BACKGROUND: Literature has attempted to correlate pitching workload with risk of ulnar collateral ligament (UCL) injury; however, limited data are available in evaluating workload and its relationship with the need for revision reconstruction in Major League Baseball (MLB) pitchers. METHODS: We identified 29 MLB pitchers who underwent primary UCL reconstruction surgery and subsequently required revision reconstruction and compared them with 121 MLB pitchers who underwent primary reconstruction but did not later require revision surgery...
February 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28102105/pitching-form-determines-probabilistic-structure-of-errors-in-pitch-location
#4
Masahiro Shinya, Shinji Tsuchiya, Yousuke Yamada, Kimitaka Nakazawa, Kazutoshi Kudo, Shingo Oda
According to recent motor control studies, it is important to know probabilistic structure of his/her own motor errors to choose an optimal motor plan (i.e., where you aim at) to maximise the expected gain. In this study, we questioned if pitching form determines the probabilistic structure of pitching errors in baseball pitchers. Eighteen collegiate baseball pitchers with various pitching forms including right- and left-handed overarm, sidearm and underarm throwers threw 100 pitches aiming at a target located 90 cm above the ground...
January 19, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28018659/mutualists-or-parasites-context-dependent-influence-of-symbiotic-fly-larvae-on-carnivorous-investment-in-the-albany-pitcher-plant
#5
Samuel J Lymbery, Raphael K Didham, Stephen D Hopper, Leigh W Simmons
Carnivorous plants allocate more resources to carnivorous structures under nutrient-limited conditions, and relative investment can also be influenced by animals (infauna) that live in association with these plants and feed on their prey. We investigated these effects within a population of the pitcher plant Cephalotus follicularis containing varying densities of larvae of the fly Badisis ambulans. For plants with a relatively high proportion of adult pitchers, increasing larval density was associated with lower relative leaf allocation to new pitcher buds...
November 2016: Royal Society Open Science
https://www.readbyqxmd.com/read/28013545/room-temperature-magnetically-ordered-polar-corundum-gafeo3-displaying-magnetoelectric-coupling
#6
Hongjun J Niu, Michael J Pitcher, Alex J Corkett, Sanliang Ling, Pranab Mandal, Marco Zanella, Karl Dawson, Plamen Stamenov, Dmitry Batuk, Artem M Abakumov, Craig L Bull, Ronald I Smith, Claire A Murray, Sarah J Day, Ben Slater, Furio Cora, John B Claridge, Matthew J Rosseinsky
The polar corundum structure type offers a route to new room temperature multiferroic materials, as the partial LiNbO3-type cation ordering that breaks inversion symmetry may be combined with long range magnetic ordering of high spin d5 cations above room temperature in the AFeO3 system. We report the synthesis of a polar corundum GaFeO3 by a high-pressure high-temperature route and demonstrate that its polarity arises from partial LiNbO3-type cation ordering by complementary use of neutron, X-ray and electron diffraction methods...
December 24, 2016: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28011742/the-superior-temporal-sulcus-is-causally-connected-to-the-amygdala-a-combined-tbs-fmri-study
#7
David Pitcher, Shruti Japee, Lionel Rauth, Leslie G Ungerleider
: Non-human primate neuroanatomical studies have identified a cortical pathway from the superior temporal sulcus (STS) projecting into dorsal sub-regions of the amygdala, but whether this same pathway exists in humans is unknown. Here, we addressed this question by combining thetaburst transcranial magnetic stimulation (TBS) with functional magnetic resonance imaging (fMRI) to test the prediction that the STS and amygdala are functionally connected during face perception. Human participants (N=17) were scanned, over two sessions, while viewing 3-second video clips of moving faces, bodies and objects...
December 23, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28011261/common-femoral-artery-access-on-youtube-what-practices-are-being-shown-and-who-is-delivering-the-message
#8
Grayson S Pitcher, Daniel H Newton, Michael F Amendola
OBJECTIVES: Novice learners are increasingly turning to YouTube as a learning resource for surgical procedures. One example of such a procedure is common femoral artery puncture and sheath placement. Practitioners in several specialties perform this procedure to access the arterial system for angiography and intervention. We set forth to compare the techniques demonstrated on YouTube by the various specialists, as well as compare each specialty׳s prevalence on this website. METHODS: YouTube (www...
December 20, 2016: Journal of Surgical Education
https://www.readbyqxmd.com/read/28005101/ulnar-collateral-ligament-reconstruction-current-philosophy-in-2016
#9
E Lyle Cain, Taylor P Mathis
The ulnar collateral ligament (UCL) is the primary static restraint to valgus stress at the elbow. Since Jobe pioneered reconstruction in 1974, thousands of throwers have undergone UCL reconstruction, and good results have been achieved. The high-profile nature of the elite pitcher has brought this technique into the spotlight, and extensive research has been performed with new techniques emerging. The standard reconstruction, modified only slightly since Jobe's original description, remains the gold standard for treatment of UCL insufficiency...
November 2016: American Journal of Orthopedics
https://www.readbyqxmd.com/read/27984381/bronchoscopist-guided-sedation-in-ebus-tbna-can-the-pitcher-also-be-a-hitter
#10
Preyas J Vaidya, Prashant N Chhajed
No abstract text is available yet for this article.
January 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/27982472/a-switchable-cross-species-liquid-repellent-surface
#11
Yu Huang, Birgitt Boschitsch Stogin, Nan Sun, Jing Wang, Shikuan Yang, Tak-Sing Wong
A switchable cross-species liquid-repellent surface is developed that can rapidly switch between two distinct liquid-repellent modes: (1) the superhydrophobic mode, modeled after lotus leaves, and (2) the slippery mode, modeled after the pitcher plant peristome. Adaptive liquid repellency and programmable fog harvesting have been demonstrated as application examples for the new switchable surface.
December 16, 2016: Advanced Materials
https://www.readbyqxmd.com/read/27974494/correction-to-bacteria-facilitate-prey-retention-by-the-pitcher-plant-darlingtonia-californica
#12
David W Armitage
No abstract text is available yet for this article.
December 2016: Biology Letters
https://www.readbyqxmd.com/read/27972562/cost-effectiveness-analysis-of-regorafenib-in-gastrointestinal-stromal-tumours-in-england-using-crossover-adjustment-methods
#13
A Pitcher, E Grabbi, M Madin-Warburton, S Vadgama
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27972183/cost-per-responder-of-lixisenatide-versus-rapid-acting-insulin-intensification-regimens-in-an-insulin-exposed-type-2-diabetes-mellitus-t2dm-population
#14
M Afonso, F Ryan, A Pitcher, E Lew
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27972153/combining-a-real-world-observational-study-and-a-network-meta-analysis-of-randomised-controlled-trials-to-determine-relative-treatment-effects-in-type-2-diabetes
#15
T Reason, M Hankins, E Lovato, A Pitcher, M Schlueter, K R Abrams
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27971594/predicting-response-to-anti-vascular-endothelial-growth-factor-treatment-using-electronic-medical-record-data-in-eyes-with-neovascular-age-related-macular-degeneration
#16
C Andrews, K D'Souza, S Lacey, J Rigg, A Pitcher, F Milnes
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27970420/the-impact-of-dynamic-transmission-modelling-on-the-estimated-cost-effectiveness-of-treatment-for-chronic-hepatitis-c-in-the-united-kingdom
#17
M Madin-Warburton, A Pitcher, N Martin
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27959931/mate2-expression-is-associated-with-cancer-cell-response-to-metformin
#18
Sanjana Chowdhury, Eric Yung, Melania Pintilie, Hala Muaddi, Selim Chaib, ManTek Yeung, Manlio Fusciello, Jenna Sykes, Bethany Pitcher, Anna Hagenkort, Trevor McKee, Ravi Vellanki, Eric Chen, Robert G Bristow, Bradly G Wouters, Marianne Koritzinsky
BACKGROUND: There is great interest in repurposing the commonly prescribed anti-diabetic drug metformin for cancer therapy. Intracellular uptake and retention of metformin is affected by the expression of organic cation transporters (OCT) 1-3 and by multidrug and toxic compound extrusion (MATE) 1-2. Inside cells, metformin inhibits mitochondrial function, which leads to reduced oxygen consumption and inhibition of proliferation. Reduced oxygen consumption can lead to improved tumor oxygenation and radiation response...
2016: PloS One
https://www.readbyqxmd.com/read/27940806/treatment-for-ulnar-neuritis-around-the-elbow-in-adolescent-baseball-players-factors-associated-with-poor-outcome
#19
Masahiro Maruyama, Hiroshi Satake, Masatoshi Takahara, Mikio Harada, Tomohiro Uno, Nariyuki Mura, Michiaki Takagi
BACKGROUND: Ulnar neuritis around the elbow is one of the injuries seen in throwing athletes. Outcomes of nonsurgical treatment and factors associated with failure outcomes have not been reported. PURPOSE: To investigate the outcomes of treatments for ulnar neuritis in adolescent baseball players. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: We assessed 40 male baseball players with a mean age of 15.0 years (range, 13-17 years) who presented with ulnar neuritis...
December 9, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27903163/ultrasound-imaging-of-ulnar-collateral-ligament-injury
#20
Arie J van Duijn, Shawn D Felton
The patient was an 18-year-old collegiate baseball pitcher who injured his right throwing elbow during an overhead slider pitch. As a part of a study, preinjury ultrasound images of the throwing arm were obtained 2 weeks prior to the injury. One day postinjury, repeat ultrasound imaging of the medial elbow was performed. The attending team physician ordered a magnetic resonance arthrogram 2 days after injury, which confirmed the presence of a complete tear of the ulnar collateral ligament. J Orthop Sports Phys Ther 2016;46(12):1086...
December 2016: Journal of Orthopaedic and Sports Physical Therapy
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