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Grafting vitiligo

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https://www.readbyqxmd.com/read/29913258/motorized-0-8-mm-micro-punch-grafting-for-refractory-vitiligo-a-retrospective-study-of-230-cases
#1
Jung Min Bae, Ji Hae Lee, Hyuck Sun Kwon, Jiehoon Kim, Dong Seok Kim
BACKGROUND: Punch grafting for vitiligo has been time-consuming and may result in cobblestone-like appearances. We devised a motorized 0.8 mm micro-punch grafting procedure to overcome these limitations. OBJECTIVE: To assess the therapeutic effectiveness and adverse events associated with micro-punch grafting in refractory vitiligo. METHODS: We retrospectively reviewed 230 lesions in 208 patients with stable vitiligo who underwent motorized 0...
June 15, 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29797713/syringes-versus-chinese-cups-in-harvesting-suction-induced-blister-graft-a-randomized-split-body-study
#2
Tag S Anbar, Nayera H Moftah, Mohammad A M El-Khayyat, Hasan M El-Fakahany, Amal T Abdel-Rahman, Enas K Saad
BACKGROUND: Suction blister grafting (SBG) is a technique where the pigmented epidermis is harvested from the donor site by induction of a blister using different suction methods as syringes, Chinese cups, suction device, etc. However, pain, time consumption, incomplete blister formation, and failure of blister development are the main limitations. OBJECTIVE: To compare between cups and syringes of similar diameter in inducing suction blisters. PATIENTS AND METHODS: In 30 patients with stable nonsegmental vitiligo, 2-cm-diameter (20 ml) syringe was applied on the anterolateral aspect of one thigh and a 2-cm-diameter cup on the corresponding site of the other thigh where right and left sides were chosen randomly...
May 24, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29782303/clindamycin-induced-maculopapular-exanthema-with-preferential-involvement-of-striae-distensae-a-koebner-phenomenon
#3
Benigno Monteagudo, Miguel Cabanillas, Pilar Iriarte, Aquilina Ramírez-Santos, Elvira León-Muinos, Daniel González-Vilas, Óscar Suárez-Amor
Clindamycin is a lincomycin-derived antibiotic useful for the treatment of anaerobic and Gram-positive aerobic bacterial infections. Cutaneous adverse reactions are usually maculopapular exanthemas, although hypersensitivity syndrome, acute generalized exanthematous pustulosis, and Stevens-Johnson syndrome have also been reported (1). We report the case of a patient with a maculopapular rash triggered by clindamycin who developed cutaneous lesions on striae distensae (SD). A 47-year-old woman was referred to our clinic for pruritic cutaneous lesions which had started 6 days earlier...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29741410/management-of-resistant-halo-nevi
#4
Sherif S Awad, Rasha Ta Abdel Aziz, Sahar S Mohammed
BACKGROUND: Halo nevus (HN) is a rare dermatologic disorder characterized by typical whitish rim surrounding an existing melanocytic nevus resembling halo. It is a cosmetic problem that may be linked to vitiligo, and it is advised to remove these nevi in order to avoid development of vitiligo. OBJECTIVES: The aim of the present study is to evaluate the cosmetic outcome after nevus removal and leukoderma dermabrasion with epithelial graft followed by narrow-band ultraviolet B (NB-UVB) phototherapy as management of resistant halo nevi and avoidance of development of vitiligo...
May 9, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29731587/suction-blister-epidermal-grafting-for-vitiligo-involving-angles-of-lip-experience-of-112-patients
#5
Bikash R Kar, Chinmoy Raj
Background: Lip vitiligo is usually resistant to medical modalities of treatment, and in all these cases, surgery offers a hope. Suction blister grafting (SBG) has been tried since long for lip vitiligo with high rate of success. There have been no long-term follow-up studies of patients with SBG at a difficult-to-treat site like angles of lip, which prompted us to conduct this study. Aims and Objectives: To assess the pigmentation rate and patient satisfaction of SBG on vitiligo involving angles of lip...
January 2018: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/29664513/vitiligo-type-cutaneous-manifestation-of-chronic-graft-versus-host-disease-case-report
#6
Karla Gálvez, Paula Muñoz, Valentina Vera, Claudio Arce
INTRODUCTION: Graft-versus-host disease (GVHD) is caused by a pathologic and destructive response of the organism as a result of the interaction between donor immunocompetent T lymphocytes and the recipient tisular antigens. It's considered the most serious complication of hematopoietic stem cell transplantation, most frequently described after bone marrow transplantation (BMT). The skin is usually the first and most commonly affected organ, in both acute and chronic, with a variable clinical spectrum of presentation...
February 2018: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/29588248/nonmalignant-late-cutaneous-changes-after-allogeneic-hematopoietic-stem-cell-transplant-in-children
#7
Jennifer T Huang, Johanna S Song, Elena B Hawryluk, Wendy B London, Dongjing Guo, Madhumitha Sridharan, David E Fisher, Leslie E Lehmann, Christine N Duncan
BACKGROUND: There are limited pediatric data on nonmalignant cutaneous changes, including autoimmune conditions and permanent alopecia, after hematopoietic stem cell transplantation (HSCT). OBJECTIVE: We sought to characterize late cutaneous changes and associated risk factors after allogeneic HSCT in children. METHODS: A cross-sectional cohort study of pediatric HSCT recipients was performed at a single institution. All participants underwent a full skin examination...
March 26, 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29431372/pigmentation-disorders-diagnosis-and-management
#8
Scott Plensdorf, Maria Livieratos, Nabil Dada
Pigmentation disorders are commonly diagnosed, evaluated, and treated in primary care practices. Typical hyperpigmentation disorders include postinflammatory hyperpigmentation, melasma, solar lentigines, ephelides (freckles), and café au lait macules. These conditions are generally benign but can be distressing to patients. Appropriate dermatologic history, skin examination, and skin biopsy, when appropriate, can help exclude melanoma and its precursors. In addition to addressing the underlying condition, hyperpigmentation is treated with topical agents, chemical peels, cryotherapy, light or laser therapy, or a combination of these methods...
December 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/29419905/once-weekly-targeted-excimer-light-produced-modest-repigmentation-of-vitiligo-over-a-20-week-period
#9
LETTER
S Ayob, S E Cockayne, D J Gawkrodger
No abstract text is available yet for this article.
February 8, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29364459/optimizing-suction-blister-epidermal-graft-technique-in-the-surgical-treatment-of-vitiligo
#10
Gerson Dellatorre, Wagner Bertolini, Caio Cesar Silva de Castro
Surgical management of vitiligo is considered an excellent terapeutic option for recalcitrant cases, provided the disease is stable and there is absence of Koebner phenomenom. Among surgical modalities, Suction Blister Epidermal Graft is a low cost and effective option (65 to 100% repigmentation can be achieved in up to 80% of patients). We describe how it can be optimized by using an alternative suction equipment, by customization of graft format and by application of an anesthetic technique that substantially reduces procedure time...
November 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29318598/efficacy-and-safety-of-noncultured-melanocyte-keratinocyte-transplant-procedure-for-vitiligo-and-other-leukodermas-a-critical-analysis-of-the-evidence
#11
REVIEW
Paras P Vakharia, Dylan E Lee, Amor Khachemoune
Vitiligo is an acquired pigmentary skin of depigmentation occurring secondary to melanocyte destruction. Vitiligo and other leukodermas have a profound impact on quality of life. Current therapies include medical options, such as phototherapy, topical and systemic corticosteroids, topical calcineurin inhibitors, immunomodulators, and antioxidiants, and surgical options. Surgical options provide melanocytic cells to previously depigmented areas and use either tissue grafting or cellular grafting methods. Topical treatments are often insufficient, and many of the current surgical procedures have shown variable response rates...
January 10, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/28979623/-piebaldisme-a-rare-genodermatosis
#12
Fatima Zahra Debbarh, Fatima Zahra Mernissi
Piebaldism is a rare autosomal dominant genodermatosis. It is due to congenital absence of melanocytes in the affected areas. We report a case. A 5 year old girl born to consanguineous parents and with similar cases in her mother's; she presented since birth achromic lesions on the legs with a steady evolution. clinical examination showed confluent achromic macules and poliosis (A) with no contrast enhancement under Wood lamp and several coffee-with-milk colored spots on the trunk and thighs(B). The diagnosis of piebaldism was made...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28855688/maximizing-non-enzymatic-methods-for-harvesting-adipose-derived-stem-from-lipoaspirate-technical-considerations-and-clinical-implications-for-regenerative-surgery
#13
Barbara Bellei, Emilia Migliano, Marinella Tedesco, Silvia Caputo, Mauro Picardo
In the past decade, adipose tissue has become a highly interesting source of adult stem cells for plastic surgery and regenerative medicine. The adipose source offers two options for the isolation of regenerative cells: the enzymatic digestion an expensive time-consuming procedure lacking a common standard operating protocol, or the non-enzymatic dissociation methods based on mechanical forces to break the processed adipose tissue. Here, we propose innovative inexpensive non-enzymatic protocols to collect and concentrate clinically useful regenerative cells from adipose tissue by centrifugation of the infranatant fraction of lipoaspirate as first step, usually discarded as a byproduct of the surgical procedure, and by fat shaking and wash as second enrichment step...
August 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28852293/simplified-non-cultured-non-trypsinised-epidermal-cell-graft-technique-followed-by-psoralen-and-ultraviolet-a-light-therapy-for-stable-vitiligo
#14
Dilip Kachhawa, Pankaj Rao, Gyaneshwar Kalla
BACKGROUND AND AIMS: Stable vitiligo can be treated by various surgical procedures. Non-cultured melanocyte grafting techniques were developed to overcome the time-consuming process of culture while at the same time providing acceptable results. All the techniques using non-cultured melanocyte transfer involve trypsinisation as an integral step. Jodhpur technique used by the author is autologous, non-cultured, non-trypsinised, epidermal cell grafting. SETTINGS AND DESIGN: The study was conducted on patients visiting the dermatology outpatient department of a tertiary health centre in Western Rajasthan...
April 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/28799192/wood-s-lamp-for-vitiligo-disease-stability-and-early-recognition-of-initiative-pigmentation-after-epidermal-grafting
#15
Yen-Jen Wang, Chang-Cheng Chang, Kun-Lin Cheng
The prerequisite for a successful vitiligo epidermal grafting surgery is the stable status of the disease. We used Wood's lamp to assess vitiligo activity to determine the disease stability, surgical grafting timing and the early recognition of re-pigmentation after grafting. Amelanotic lesions with sharply demarcated borders are typically stable and are good candidates for grafting. The re-pigmentation was first recognised under Wood's lamp as hypochromic islands, which progressed to normally pigmented islands...
December 2017: International Wound Journal
https://www.readbyqxmd.com/read/28538029/autologous-biological-dressing-for-recipient-area-in-cellular-grafting-of-vitiligo
#16
Sanjeev Gupta, Ravi Shankar Jangra, Karalikkattil T Ashique, Somesh Gupta
No abstract text is available yet for this article.
May 22, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28403523/autologous-cell-suspension-grafting-in-segmental-vitiligo-and-piebaldism-a-randomized-controlled-trial-comparing-full-surface-and-fractional-co-2-laser-recipient-site-preparations
#17
J E Lommerts, A A Meesters, L Komen, M W Bekkenk, M A de Rie, R M Luiten, A Wolkerstorfer
BACKGROUND: Autologous noncultured cell suspension transplantation is an effective treatment for repigmentation in segmental vitiligo and piebaldism. Full surface laser ablation is frequently used to prepare the recipient site before cell suspension transplantation, even though the optimal laser settings and ablation depth are unknown. OBJECTIVES: To assess the efficacy and safety of less invasive recipient-site preparations. METHODS: In a randomized, observer-blinded, controlled trial we compared different recipient-site preparations before cell suspension transplantation in segmental vitiligo and piebaldism...
November 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28272910/punch-graft-versus-follicular-hair-transplantation-in-the-treatment-of-stable-vitiligo
#18
Essam-Elden Mohamed Mohamed, Abdel-Khalek Younes, Ahmed Osmand, Refaat Mohamed, Mahmoud Makki, Marwa Younis
OBJECTIVE: To compare the efficacy of follicular hair transplantation and mini punch graft in the treatment of stable vitiligo. METHODS: Thirty-two patients with stable vitiligo were included in this comparative study. A single patch from each patient was divided into two halves: one half was treated by punch graft, while the other half was treated by follicular hair transplantation followed by excimer light twice weekly, and the outcome was assessed at 0, 1, 3 and 6 months post operatively by photography and quartile scale...
October 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28169015/janus-kinase-inhibitors-in-dermatology-a-systematic-review
#19
REVIEW
Rony Shreberk-Hassidim, Yuval Ramot, Abraham Zlotogorski
BACKGROUND: Janus kinase (JAK) inhibitors are emerging as a promising new treatment modality for many inflammatory conditions. OBJECTIVE: Our aim was to systematically review the available data on the use of JAK inhibitors in cutaneous diseases. METHODS: This is a systematic review of PubMed and ClinicalTrials.gov. RESULTS: One hundred thirty-four articles matched our search terms, of which 78 were original articles and 12 reports on adverse events...
April 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28163453/reduction-of-blister-formation-time-in-suction-blister-epidermal-grafting-in-vitiligo-patients-using-a-household-hair-dryer
#20
Shweta Arora, Bikash Ranjan Kar
BACKGROUND: Suction blister epidermal grafting (SBEG) is a simple and effective way of surgical repigmentation in vitiligo. The major problem faced is the time taken for the formation of blisters. Temperature at the suction site is one of the factors affecting the blister formation time. AIMS AND OBJECTIVES: To reduce the blister formation time in SBEG by increasing the surface temperature to 44°C. MATERIALS AND METHODS: This is a left-right comparison study...
October 2016: Journal of Cutaneous and Aesthetic Surgery
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