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https://www.readbyqxmd.com/read/28214690/safety-and-efficacy-of-a-polyherbal-formulation-for-the-management-of-dyslipidemia-and-hyperglycemia-in-patients-with-advanced-stage-of-type-2-diabetes
#1
Mahdi Zarvandi, Hassan Rakhshandeh, Mohammad Abazari, Reza Shafiee-Nick, Ahmad Ghorbani
The present clinical trial was designed to evaluate the safety and efficacy of a polyherbal formulation (PHF) consisted of Allium sativum, Aloe vera, Nigella sativa, Plantago psyllium, Silybum marianum and Trigonella foenum-graecum for controlling dyslipidemia and hyperglycemia in patients with advanced-stage of type-2 diabetes. An open-label phase I trial was carried out on 30 patients who had hyperlipidemia and hyperglycemia before the beginning of the trial in spite of receiving statins and oral hypoglycemic drugs...
February 16, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28150480/adequate-dietary-fiber-supplement-along-with-tone-concept-can-help-avoid-surgery-in-most-patients-with-advanced-hemorrhoids
#2
Pankaj Garg, Pratiksha Singh
BACKGROUND: The root cause of hemorrhoids are three deranged defecation habits (DDH) - (1) increased straining, (2) prolonged defecation-time and, (3) frequent bowel-motions. These DDH are responsible for development of new hemorrhoids, progression of existing hemorrhoids and hemorrhoidal rupture (bleeding). DDH can be corrected by TONE concept. TONE entails specifying exact treatment goals (T-Three minutes at defecation, O-Once a day defecation- frequency, N-No straining during passing motions, E-Enough fiber)...
February 1, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28146065/effect-on-insulin-glucose-and-lipids-in-overweight-obese-australian-adults-of-12-months-consumption-of-two-different-fibre-supplements-in-a-randomised-trial
#3
Sebely Pal, Suleen Ho, Roland J Gahler, Simon Wood
Higher fibre intakes are associated with risk reduction for chronic diseases. This study investigated the effects of supplementation with PolyGlycopleX(®) (PGX), a complexed polysaccharide, on insulin, glucose and lipids in overweight and obese individuals. In this double-blind 12 months study, participants were randomised into three groups: control (rice flour); PGX or psyllium (PSY). Participants followed their usual lifestyle and diet but consumed 5 g of their supplement before meals. Insulin was significantly lower in the PGX and PSY groups compared to control at 3 and 6 months and in the PSY group compared to control at 12 months...
January 29, 2017: Nutrients
https://www.readbyqxmd.com/read/27987136/management-of-chronic-constipation-in-patients-with-diabetes-mellitus
#4
REVIEW
V G M Prasad, Philip Abraham
AIM: The aim of this review is to provide an overview of the clinical assessment and evidence-based treatment options for managing diabetes-associated chronic constipation. METHODS: A literature search of published medical reports in English language was performed using the OVID Portal, from PUBMED and the Cochrane Database of Systematic Reviews, from inception to October 2015. A total of 145 abstracts were identified; duplicate publications were removed and 95 relevant full-text articles were retrieved for potential inclusion...
December 17, 2016: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/27891167/effect-on-body-weight-and-composition-in-overweight-obese-australian-adults-over-12%C3%A2-months-consumption-of-two-different-types-of-fibre-supplementation-in-a-randomized-trial
#5
Sebely Pal, Suleen Ho, Roland J Gahler, Simon Wood
BACKGROUND/OBJECTIVES: Higher fibre intakes are associated with risk reduction for chronic diseases. However, many people find difficulty in consuming sufficient fibre through their diet. Supplements may be an effective alternative. We aimed to investigate the effects of PolyGlycopleX® (PGX®), a proprietary polysaccharide complex and a proprietary Psyllium product (PgxSyl™) (PSY) on diet, body weight and composition in overweight and obese individuals. SUBJECTS/METHODS: This was a double-blind 52 weeks study with 159 people randomized to 3 groups: control (rice flour); PGX (PGX) and proprietary psyllium (PSY)...
2016: Nutrition & Metabolism
https://www.readbyqxmd.com/read/27876985/in-vitro-anti-leishmanial-activity-of-satureja-hortensis-and-artemisia-dracunculus-extracts-on-leishmania-major-promastigotes
#6
Farzaneh Mirzaei, Ali Fattahi Bafghi, Mohammad Ali Mohaghegh, Hossein Zarei Jaliani, Roghiyeh Faridnia, Hamed Kalani
Cutaneous leishmaniasis is one of the important skin diseases with diverse clinical manifestations. With an incidence of 0.7-1.3 million cases annually, this disease is often reported from six countries, including Iran. Accordingly, the purpose of this study was to evaluate the anti-leishmanial effect of the three plant hydroalcoholic extracts including fleawort (Plantago psyllium L.), savory (Satureja hortensis L.) and tarragon (Artemisia dracunculus L.) on Leishmania major promastigotes. The hydroalcoholic extract from each plant was extracted and its anti-leishmanial effect was evaluated in different concentrations (100-1000 µg/ml) and at various hours (24, 48 and 72 h)...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27871178/use-of-polyethylene-glycol-in-functional-constipation-and-fecal-impaction
#7
Miguel Mínguez, Antonio López Higueras, Javier Júdez
OBJECTIVE: The objective of this study was to evaluate in an analytical and descriptive manner the evidence published so far on the use of polyethylene glycol (PEG), with or without electrolytes, in the management of functional constipation and the treatment of fecal impaction. METHODOLOGY: Search on MEDLINE, EMBASE and Cochrane databases until May 2016 of all publications adjusted to the following terms: constipation AND/OR fecal impaction AND (PEG OR polyethylene glycol OR macrogol OR movicol OR idralax OR miralax OR transipeg OR forlax OR golytely OR isocolan OR mulytely) NOT colonoscopy...
December 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/27863994/understanding-the-physics-of-functional-fibers-in-the-gastrointestinal-tract-an-evidence-based-approach-to-resolving-enduring-misconceptions-about-insoluble-and-soluble-fiber
#8
Johnson W McRorie, Nicola M McKeown
Enduring misconceptions about the physical effects of fiber in the gut have led to misunderstandings about the health benefits attributable to insoluble and soluble fiber. This review will focus on isolated functional fibers (eg, fiber supplements) whose effects on clinical outcomes have been readily assessed in well-controlled clinical studies. This review will also focus on three health benefits (cholesterol lowering, improved glycemic control, and normalizing stool form [constipation and diarrhea]) for which reproducible evidence of clinical efficacy has been published...
February 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/27821191/nutritional-management-of-hyperapob
#9
Valérie Lamantia, Allan Sniderman, May Faraj
Plasma apoB is a more accurate marker of the risk of CVD and type 2 diabetes (T2D) than LDL-cholesterol; however, nutritional reviews targeting apoB are scarce. Here we reviewed eighty-seven nutritional studies and present conclusions in order of strength of evidence. Plasma apoB was reduced in all studies that induced weight loss of 6-12 % using hypoenergetic diets (seven studies; 5440-7110 kJ/d; 1300-1700 kcal/d; 34-50 % carbohydrates; 27-39 % fat; 18-24 % protein). When macronutrients were compared in isoenergetic diets (eleven studies including eight randomised controlled trials (RCT); n 1189), the diets that reduced plasma apoB were composed of 26-51 % carbohydrates, 26-46 % fat, 11-32 % protein, 10-27 % MUFA, 5-14 % PUFA and 7-13 % SFA...
December 2016: Nutrition Research Reviews
https://www.readbyqxmd.com/read/27766217/evaluation-of-the-effect-of-psyllium-on-the-viability-of-lactobacillus-acidophilus-in-alginate-polyl-lysine-beads
#10
Jaleh Esmaeilzadeh, Hossein Nazemiyeh, Maryam Maghsoodi, Farzaneh Lotfipour
Purpose: Psylliumseeds are used in traditional herbal medicine to treat various disorders. Moreover, as a soluble fiber, psyllium has potential to stimulate bacterial growth in digestive system. We aimed to substitute alkali-extractable polysaccharides of psyllium for alginate in beads with second coat of poly-l-lysine to coat Lactobacillus acidophilus. Methods: Beads were prepared using extrusion technique. Poly-l-lysine as second coat was incorporated on optimum alginate/psyllium beads using immersion technique...
September 2016: Advanced Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/27761216/comparative-study-on-the-effect-of-plantago-psyllium-and-ocimum-basilicum-seeds-on-anthropometric-measures-in-nonalcoholic-fatty-liver-patients
#11
Shahab-Aldin Akbarian, Sedigheh Asgary, Awat Feizi, Bijan Iraj, Gholamreza Askari
BACKGROUND: Due to the attribution of fatty liver with some chronic diseases such as obesity, finding a way to control obesity can be useful for the management of fatty liver. This study was performed to assess the effects of Plantago psyllium (PP) and Ocimum basilicum (OB) on anthropometric measurements in people with hepatic steatosis. METHODS: All patients with nonalcoholic fatty liver disease (NAFLD) were enrolled in this four-arm parallel, randomized, and single blind trial...
2016: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/27733202/comparison-of-psyllium-feeding-at-home-and-nasogastric-intubation-of-psyllium-and-magnesium-sulfate-in-the-hospital-as-a-treatment-for-naturally-occurring-colonic-sand-geosediment-accumulations-in-horses-a-retrospective-study
#12
Ritva Kaikkonen, Kati Niinistö, Tiina Lindholm, Marja Raekallio
BACKGROUND: Ingestion of geosediment (further referred as sand) may cause weight loss, diarrhea and acute or recurrent colic in horses. Our aim was to compare the efficacy of three treatment protocols in clearing colonic sand accumulations in clinical patients. This retrospective clinical study consisted of 1097 horses and ponies, which were radiographed for the presence of colonic sand. Horses included to the study (n = 246) were displaying areas of sand in the radiographs of ≥75 cm(2) and were treated medically monitoring the response with radiographs...
October 12, 2016: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/27733151/soluble-fibers-from-psyllium-improve-glycemic-response-and-body-weight-among-diabetes-type-2-patients-randomized-control-trial
#13
Ayman S Abutair, Ihab A Naser, Amin T Hamed
BACKGROUND: Water-soluble dietary fibers intake may help control blood glucose and body weight. OBJECTIVE: The objective of the study was to determine whether soluble fiber supplementation from psyllium improves glycemic control indicators and body weight in type 2 diabetic patients. METHOD: Forty type 2 diabetes patients, non-smoker, aged >35 years were stratified to different strata according to sex, age, body mass index (BMI) and fasting blood sugar level (FBS) and randomly assigned into two groups; The intervention group which consists of 20 participants was on soluble fiber (10...
October 12, 2016: Nutrition Journal
https://www.readbyqxmd.com/read/27722358/sodium-ion-interaction-with-psyllium-husk-plantago-sp
#14
M A Jimoh, W MacNaughtan, H E L Williams, D Greetham, R L Linforth, I D Fisk
The nature of and factors effecting sodium interactions with psyllium were investigated in vitro. In a batch extraction system, psyllium mucilage gel retained at least 50% of sodium across a range of concentrations (5-300 mg sodium per g psyllium) and pH (2-10) environments. FTIR and Na NMR analyses of psyllium gels indicated that binding was complex with non-specific multi-site interactions. The potential use of psyllium husk as a binding agent for the reduction of bioavailable sodium was therefore evaluated...
September 14, 2016: Food & Function
https://www.readbyqxmd.com/read/27696378/probiotics-fiber-and-herbal-medicinal-products-for-functional-and-inflammatory-bowel-disorders
#15
Diego Currò, Gianluca Ianiro, Silvia Pecere, Stefano Bibbò, Giovanni Cammarota
Functional bowel disorders (FBDs), mainly irritable bowel syndrome (IBS) and functional constipation (FC, also called chronic idiopathic constipation), are highly diffused worldwide. Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, although less common, has a strong impact on patients' quality of life, as well as is highly expensive for our healthcare. A definite cure for those disorders is still yet to come. Over the years, several therapeutic approaches complementary or alternative to traditional pharmacological treatments, including probiotics, prebiotics, synbiotics, fiber and herbal medicinal products, have been investigated for the management of both groups of diseases...
October 3, 2016: British Journal of Pharmacology
https://www.readbyqxmd.com/read/27691938/medical-management-of-coelomic-distention-abnormal-swimming-substrate-retention-and-hematologic-changes-in-a-reef-manta-ray-manta-alfredi
#16
Alexa J McDermott, Cara L Field, Lisa A Hoopes, Tonya M Clauss
An adult, female, reef manta ray (Manta alfredi) was evaluated for abnormal swimming and coelomic distention after colliding with a floating dock in an exhibit. Initial clinical signs included abnormal posture and swimming. Clinical signs progressed to include muscle wasting, poor body condition, and coelomic distention. Further diagnostics revealed excessive exhibit substrate within the gastrointestinal tract, gastric ulcers, free coelomic fluid, possible spinal lesion, possible uterine abnormality, and hematologic changes...
September 2016: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/27680987/fermented-fiber-supplements-are-no-better-than-placebo-for-a-laxative-effect
#17
Johnson W McRorie, William D Chey
BACKGROUND: Misconceptions about the effects of dietary fiber and 'functional' fiber on stool parameters and constipation persist in the literature. METHODS: A comprehensive literature review was conducted with the use of the Scopus and PubMed scientific databases to identify and objectively assess well-controlled clinical studies that evaluated the effects of fiber on stool parameters and constipation. RESULTS: The totality of well-controlled randomized clinical studies show that, to exert a laxative effect, fiber must: (1) resist fermentation to remain intact throughout the large bowel and present in stool, and (2) significantly increase stool water content and stool output, resulting in soft/bulky/easy-to-pass stools...
November 2016: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/27636880/suppression-of-psyllium-husk-suspension-viscosity-by-addition-of-water-soluble-polysaccharides
#18
Madhuvanti S Kale, Madhav P Yadav, Kyle A Hanah
Psyllium seed husk is an insoluble dietary fiber with many health benefits. It can absorb many times its weight in water, forming very viscous suspensions, which have low palatability and consumer acceptance. We report here a novel approach for decreasing its viscosity, involving inclusion of a soluble polysaccharide in the suspension. This leads to a drastic decrease (up to 87%) in viscosity of suspensions, while maintaining the same dosage level of psyllium and also delivering a significant amount of soluble dietary fiber such as corn bio-fiber gum in a single serving...
October 2016: Journal of Food Science
https://www.readbyqxmd.com/read/27516674/medical-mucilage-used-in-traditional-persian-medicine-practice
#19
Ghazaleh Heydarirad, Rasool Choopani, Pasalar Mehdi, Jamileh Mahdavi Jafari
BACKGROUND: Mucilage compounds are pharmaceutically important polysaccharides that have an extensive range of applications, including binding agents, thickeners, water retention agents, emulsion stabilizers, suspending agents, disintegrates, film formers, and gelling agents. A historical approach to medical science written by Iranian scholars could help in identifying excellent ideas and provide valuable information in this field for proper application. The aim of the current study was to introduce some mucilage uses derived from traditional Persian medicine (TPM)...
May 2016: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27413236/determination-of-relationship-between-sensory-viscosity-rating-and-instrumental-flow-behaviour-of-soluble-dietary-fibers
#20
Simran Kaur Arora, A A Patel, Naveen Kumar, O P Chauhan
The shear-thinning low, medium and high-viscosity fiber preparations (0.15-1.05 % psyllium husk, 0.07-0.6 % guar gum, 0.15-1.20 % gum tragacanth, 0.1-0.8 % gum karaya, 0.15-1.05 % high-viscosity Carboxy Methyl Cellulose and 0.1-0.7 % xanthan gum) showed that the consistency coefficient (k) was a function of concentration, the relationship being exponential (R(2), 0.87-0.96; P < 0.01). The flow behaviour index (n) (except for gum karaya and CMC) was exponentially related to concentration (R(2), 0...
April 2016: Journal of Food Science and Technology
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