keyword
MENU ▼
Read by QxMD icon Read
search

TK Management

keyword
https://www.readbyqxmd.com/read/29503695/influence-of-distal-fusion-level-on-sagittal-spinopelvic-and-spinal-parameters-in-the-surgical-management-of-adolescent-idiopathic-scoliosis
#1
Turgut Akgül, Kerim Sarıyılmaz, Murat Korkmaz, Okan Özkunt, Özcan Kaya, Fatih Dikici
Study Design: Retrospective analysis of adolescent idiopathic scoliosis. Purpose: This study aimed to investigate the influence of distinct distal fusion levels on spinopelvic parameters in patients with adolescent idiopathic scoliosis (AIS) who underwent posterior instrumentation and fusion surgery. Overview of Literature: The distal fusion level selection in treatment of AIS is the one of milestone to effect on surgical outcome. Most of the paper focused on the coronal deformity correction and balance...
February 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/29221871/investigation-on-paper-cup-waste-degradation-by-bacterial-consortium-and-eudrillus-eugeinea-through-vermicomposting
#2
Karthika Arumugam, Seenivasagan Renganathan, Olubukola Oluranti Babalola, Vasanthy Muthunarayanan
Disposable Paper cups are a threat to the environment and are composed of 90% high strength paper with 5% thin coating of polyethylene. This polyethylene prevents the paper cup from undergoing degradation in the soil. Hence, in the present study two different approaches towards the management of paper cup waste through vermicomposting technology has been presented. The experimental setup includes 2 plastic reactors namely Vermicompost (VC) (Cow dung + Paper cup waste + Earthworm (Eudrillus eugeinea)) and Vermicompost with bacterial consortium (VCB) (Cow dung + Paper cup waste + Eudrillus eugeinea + Microbial consortia such as Bacillus anthracis, B...
April 2018: Waste Management
https://www.readbyqxmd.com/read/29199595/epidermal-growth-factor-receptor-tyrosine-kinase-a-potential-target-in-treatment-of-non-small-cell-lung-carcinoma
#3
REVIEW
Venugopal Vinod Prabhu, Niranjali Devaraj
Lung cancer is responsible for 1.6 million deaths. Approximately 80%-85% of lung cancers are of the non-small-cell variety, which includes squamous cell carcinoma, adenocarcinoma, and large-cell carcinoma. Knowing the stage of cancer progression is a requisite for determining which management approach-surgery, chemotherapy, radiotherapy, and/or immunotherapy-is optimal. Targeted therapeutic approaches with antiangiogenic monoclonal antibodies or tyrosine kinase inhibitors are one option if tumors harbor oncogene mutations...
2017: Journal of Environmental Pathology, Toxicology and Oncology
https://www.readbyqxmd.com/read/29067951/radiological-analysis-of-thoracolumbar-junctional-degenerative-kyphosis-in-patients-with-lumbar-degenerative-kyphosis
#4
Chen-Jun Liu, Zhen-Qi Zhu, Kai-Feng Wang, Shuo Duan, Shuai Xu, Hai-Ying Liu
BACKGROUND: Thoracolumbar junction (TLJ) is the transitional area between the lower thoracic spine and the upper lumbar spine. Vertebral compression fractures and proximal junctional kyphosis following spine surgery often occur in this area. Therefore, the study of development and mechanisms of thoracolumbar junctional degeneration is important for planning surgical management. This study aimed to review radiological parameters of thoracolumbar junctional degenerative kyphosis (TLJDK) in patients with lumbar degenerative kyphosis and to analyze compensatory mechanisms of sagittal balance...
November 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28502881/multilevel-schwab-grade-ii-osteotomies-for-sagittal-plane-correction-in-the-management-of-adult-spinal-deformity
#5
George M Ghobrial, Nathan H Lebwohl, Barth A Green, Joseph P Gjolaj
BACKGROUND CONTEXT: Prior reports have compared posterior column osteotomies with pedicle subtraction osteotomies in terms of utility for correcting fixed sagittal imbalance in adolescent patients with deformity. No prior reports have described the use of multilevel Smith-Petersen Osteotomies (SPOs) alone for surgical correction in the adult spinal deformity (ASD) population. PURPOSE: The study aimed to determine the utility of multilevel SPOs in the management of global sagittal imbalance in ASD patients...
May 11, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28445208/toxic-keratoconjunctivitis
#6
Grace L Paley, Anthony J Lubniewski, James J Reidy, Asim V Farooq
Toxic keratoconjunctivitis (TK) is an underrecognized complication of ophthalmic drug use and various environmental or occupational exposures. A detailed history and clinical examination are important to identify the offending agent(s). Common drug-related causes of TK include preservatives in ophthalmic medications, topical antimicrobials, and topical anesthetics. Alternatives to benzalkonium chloride as well as preservative-free formulations should be considered in patients requiring long-term topical medication...
April 25, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28365858/sagittal-balance-is-correlated-with-parkinson-s-disease-clinical-parameters-an-overview-of-spinopelvic-alignment-on-175-consecutive-cases
#7
Luciano Bissolotti, Pedro Berjano, Paola Zuccher, Andrea Zenorini, Riccardo Buraschi, Jorge Hugo Villafañe, Stefano Negrini
PURPOSE: The aim of this study was to describe the disease-related sagittal balance changes in relation to the sacro-pelvic morphology of Parkinson's Disease patients with different duration of disease. METHODS: One hundred and seventy-five consecutive Parkinson's Disease (PD) patients (102 males, 73 females; age: 55-83 years) participated in the cross-sectional study. The clinical assessment included: Hoehn Yahr (H&Y) score; Tinetti score; plumb line (PL) distance from the spinous process of C7, L3 and S1 and kyphosis apex...
October 2017: European Spine Journal
https://www.readbyqxmd.com/read/28249740/bridging-science-and-traditional-knowledge-to-assess-cumulative-impacts-of-stressors-on-ecosystem-health
#8
Chrystal S Mantyka-Pringle, Timothy D Jardine, Lori Bradford, Lalita Bharadwaj, Andrew P Kythreotis, Jennifer Fresque-Baxter, Erin Kelly, Gila Somers, Lorne E Doig, Paul D Jones, Karl-Erich Lindenschmidt
Cumulative environmental impacts driven by anthropogenic stressors lead to disproportionate effects on indigenous communities that are reliant on land and water resources. Understanding and counteracting these effects requires knowledge from multiple sources. Yet the combined use of Traditional Knowledge (TK) and Scientific Knowledge (SK) has both technical and philosophical hurdles to overcome, and suffers from inherently imbalanced power dynamics that can disfavour the very communities it intends to benefit...
February 26, 2017: Environment International
https://www.readbyqxmd.com/read/28130694/life-cycle-toxicity-assessment-of-earthworms-exposed-to-cadmium-contaminated-soils
#9
Wei-Yu Chen, Wen-Hsuan Li, Yun-Ru Ju, Chung-Min Liao, Vivian Hsiu-Chuan Liao
Cadmium (Cd) is of great concern in the soil environment and it can damage terrestrial organisms. The purpose of this study was to employ a toxicokinetic/toxicodynamic (TK/TD) approach to investigate the effects of toxicologically relevant Cd accumulation on the life cycle growth of earthworms (Lumbricus rubellus and Eisenia fetida) and to assess potential terrestrial ecosystem risk. We reanalyzed growth toxicity and whole body and pellet accumulation data linked with TK/TD and life cycle growth models to estimate key rate constants...
April 2017: Ecotoxicology
https://www.readbyqxmd.com/read/28065817/reproducibility-of-sagittal-radiographic-parameters-in-adolescent-idiopathic-scoliosis-a-guide-to-reference-values-using-serial-imaging
#10
Hwee Weng Dennis Hey, Gordon Chengyuan Wong, Chloe Xiaoyun Chan, Leok-Lim Lau, Naresh Kumar, Joseph Shantakumar Thambiah, John Nathaniel Ruiz, Ka-Po Gabriel Liu, Hee-Kit Wong
BACKGROUND CONTEXT: Knowledge of sagittal radiographic parameters in adolescent idiopathic scoliosis (AIS) patients has not yet caught up with our understanding of their roles in patients with adult spinal deformity. It is likely that more emphasis will be placed in restoring sagittal parameters for AIS patients in the future. Therefore, we need to understand how these parameters may vary in AIS to facilitate management plans. PURPOSE: This study aimed to determine the reproducibility of sagittal spinal parameters on lateral film radiographs in patients with AIS...
June 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27871330/age-is-not-a-determinant-factor-in-susceptibility-of-broilers-to-h5n2-clade-2-3-4-4-high-pathogenicity-avian-influenza-virus
#11
Kateri Bertran, Dong-Hun Lee, Charles Balzli, Mary J Pantin-Jackwood, Erica Spackman, David E Swayne
In 2014-2015, the US experienced an unprecedented outbreak of H5 clade 2.3.4.4 highly pathogenic avian influenza (HPAI) virus. The H5N2 HPAI virus outbreak in the Midwest in 2015 affected commercial turkey and layer farms, but not broiler farms. To assess any potential genetic resistance of broilers and/or age-related effects, we investigated the pathogenesis and transmission of A/turkey/Minnesota/12582/2015 (H5N2) (Tk/MN/15) virus in commercial 5-week-old broilers, 8-week-old broilers, and >30-week-old broiler breeders...
November 21, 2016: Veterinary Research
https://www.readbyqxmd.com/read/27738086/peritoneal-dialysis-related-peritonitis-due-to-melioidosis-a-potentially-devastating-condition
#12
Talerngsak Kanjanabuch, Nuttha Lumlertgul, Lachlan J Pearson, Tanittha Chatsuwan, Krit Pongpirul, Asada Leelahavanichkul, Nisa Thongbor, Gunticha Nuntawong, Laksamon Praderm, Pantiwa Wechagama, Surapong Narenpitak, Apinya Wechpradit, Worauma Punya, Guttiga Halue, Phetpailin Naka, Somboon Jeenapongsa, Somchai Eiam-Ong
♦ BACKGROUND: Melioidosis, an infectious disease caused by Burkholderia pseudomallei , is endemic in Southeast Asia and Northern Australia. Although a wide range of clinical manifestations from this organism are known, peritonitis associated with peritoneal dialysis (PD) has rarely been reported. ♦ PATIENTS AND METHODS: Peritoneal dialysis patients from all regions in Thailand were eligible for the study if they had peritonitis and either peritoneal fluid or effluent culture positive for B. pseudomallei ...
March 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/27725910/radiofrequency-hyperthermia-enhanced-herpes-simplex-virus-thymidine-kinase-ganciclovir-direct-intratumoral-gene-therapy-of-esophageal-squamous-cancers
#13
Yaoping Shi, Jianfeng Wang, Zhibin Bai, Yonggang Li, Longhua Qiu, Bo Zhai, Feng Zhang, Xiaoming Yang
Despite recent advances in surgical technique and treatment strategies for esophageal cancer (EC), to effectively manage the advanced (metastatic or disseminated) and recurrent EC still remain a great challenge. The aim of this study was to determine the feasibility of using intra-esophagus radiofrequency hyperthermia to enhance local HSV-TK/ganciclovir-mediated suicide gene therapy of an innovative animal models with orthotopic esophageal squamous cancers. Human esophageal squamous cancer (ESCa) cells were labeled with lentivirus/luciferase...
2016: American Journal of Cancer Research
https://www.readbyqxmd.com/read/27692294/standardized-cell-sources-and-recommendations-for-good-cell-culture-practices-in-genotoxicity-testing
#14
E Lorge, M M Moore, J Clements, M O'Donovan, M D Fellows, M Honma, A Kohara, S Galloway, M J Armstrong, V Thybaud, B Gollapudi, M J Aardema, J Y Tanir
Good cell culture practice and characterization of the cell lines used are of critical importance in in vitro genotoxicity testing. The objective of this initiative was to make continuously available stocks of the characterized isolates of the most frequently used mammalian cell lines in genotoxicity testing anywhere in the world ('IVGT' cell lines). This project was organized under the auspices of the International Life Sciences Institute (ILSI) Health and Environmental Sciences Institute (HESI) Project Committee on the Relevance and Follow-up of Positive Results in In Vitro Genetic Toxicity (IVGT) Testing...
October 2016: Mutation Research
https://www.readbyqxmd.com/read/27569361/radiofrequency-hyperthermia-enhanced-herpes-simplex-virus-thymidine-kinase-ganciclovir-direct-intratumoral-gene-therapy-of-hepatocellular-carcinoma
#15
Jianfeng Wang, Yaoping Shi, Zhibin Bai, Yonggang Li, Longhua Qiu, Guy Johnson, Feng Zhang, Xiaoming Yang
PURPOSE: To determine the feasibility of using radiofrequency hyperthermia (RFH) and to enhance the therapeutic effect of herpes simplex virus-thymidine kinase/ganciclovir (HSV-TK/GCV) for the treatment of hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Human HCC cells (HepG2) were first transfected with lentivirus/luciferase. For both in vitro confirmation and in vivo validation, luciferase-labeled HCC cells and HCC tumour xenografts on mice received different treatments: (i) combination therapy of intratumoral HSV-TK/GCV-mediated gene therapy plus magnetic resonance imaging heating guidewire (MRIHG)-mediated RFH; (ii) gene therapy only; (iii) RFH only; and (iv) phosphate-buffered saline (PBS) as control...
September 20, 2016: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/27542255/radiofrequency-hyperthermia-promotes-the-therapeutic-effects-on-chemotherapeutic-resistant-breast-cancer-when-combined-with-heat-shock-protein-promoter-controlled-hsv-tk-gene-therapy-toward-imaging-guided-interventional-gene-therapy
#16
Jingfeng Luo, Xiaotian Wu, Fei Zhou, Yurong Zhou, Tongchun Huang, Fei Liu, Guocan Han, Luming Chen, Weixian Bai, Xia Wu, Jihong Sun, Xiaoming Yang
OBJECTIVE: Gene therapy is a frontier in modern medicine. In the present study, we explored a new technique for the effective treatment of multidrug-resistant (MDR) breast cancer by combining fully the advantages of multidisciplinary fields, including image-guided minimally invasive interventional oncology, radiofrequency technology, and direct intratumoral gene therapy. RESULTS: Combination treatment with PHSP-TK plus RFH resulted in significantly higher TK gene transfection/expression, as well as a lower cell proliferation rate and a higher cell apoptosis index, than those of control groups...
October 4, 2016: Oncotarget
https://www.readbyqxmd.com/read/27347037/dual-modality-imaging-demonstrates-the-enhanced-antitumoral-effect-of-herpes-simplex-virus-thymidine-kinase-ganciclovir-plus-gemcitabine-combination-therapy-on-cholangiocarcinoma
#17
Jianfeng Wang, Ang Li, Mei Jin, Fan Zhang, Xiaoling Li
Herpes simplex virus-thymidine kinase/ganciclovir (HSV-TK/GCV) therapy is one of the most promising therapeutic strategies for the treatment of cholangiocarcinoma, which is the second most common hepatobiliary cancer. The aim of the present study was to evaluate the enhanced therapeutic effects of HSV-TK/GCV with gemcitabine on cholangiocarcinoma. QBC939 cholangiocarcinoma cells and mouse models of cholangiocarcinoma (established via tumor xenografts) received one of the following treatments: i) Gemcitabine therapy (3 µg/ml); ii) HSV-TK/GCV monotherapy; iii) HSV-TK/GCV + gemcitabine; and iv) control group, treated with phosphate-buffered saline...
July 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27198186/biology-and-treatment-of-cervical-adenocarcinoma
#18
Satoshi Takeuchi
Uterine cervical adenocarcinoma (ADC) has been increasing in its prevalence world widely despite the decrease of squamous cell carcinoma (SCC). It comprises nearly 20-25% of the all cervical malignancy in developed countries. The worse biological behavior had been reported in patients with intermediate- and high risk factors after surgery, and in advanced stage over Ⅲ, radiotherapy (RT) alone and concurrent chemo-radiotherapy (CCRT) with cisplatin was not always effective. As for chemotherapy (CT), the induction CT has not established, as well...
April 2016: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
https://www.readbyqxmd.com/read/26998982/-clinical-skills-of-chilean-general-practitioners-for-the-management-of-depressive-disorders
#19
Julia Acuña, Karina Rdz-Navarro, Gabriela Huepe, Alberto Botto, Marcelo Cárcamo, Juan Pablo Jiménez
BACKGROUND: Diverse and sustained efforts have been developed to improve the management of depression by general practitioners (GPs), but they have not improved treatment coverage and quality of services. AIM: To explore the level of knowledge and clinical skills to diagnose and treat depression by GPs in Primary Health Care (PHC) in the Metropolitan Area of Santiago de Chile (RM). MATERIAL AND METHODS: Theoretical knowledge (TK), diagnostic skills (DS) and treatment skills (TS) were evaluated in 56 GPs of the RM with a battery of specially designed instruments...
January 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/26524867/-diagnosis-and-treatment-of-social-anxiety-disorder
#20
REVIEW
Satoshi Asakura
Many studies of social anxiety disorder (SAD) have been conducted because diagnostic criteria are defined as social phobia in DSM-III in the West. In Japan, several studies have examined pathological conditions similar to SAD, known as taijin-kyofu (TK). This highly remarkable disorder involves a convincing fear of giving another person discomfort from one's physical faults (e.g. feeling that neighboring people detect an unpleasant smell from one's body, "jikoshu-kyofu", or feeling that neighboring people feel unpleasant because of one's appearance,"shukei-kyofu") termed "convinced subtype of TK" (c-TK; also known as offensive subtype of TK)...
2015: Seishin Shinkeigaku Zasshi, Psychiatria et Neurologia Japonica
keyword
keyword
27823
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"