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Organisational effectiveness

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https://www.readbyqxmd.com/read/28821770/drought-and-exogenous-abscisic-acid-alter-hydrogen-peroxide-accumulation-and-differentially-regulate-the-expression-of-two-maize-rd22-like-genes
#1
Kyle Phillips, Ndiko Ludidi
Increased biosynthesis of abscisic acid (ABA) occurs in plants in response to water deficit, which is mediated by changes in the levels of reactive oxygen species such as H2O2. Water deficit and ABA induce expression of some RD22-like proteins. This study aimed to evaluate the effect of water deficit and exogenous ABA (50 µM ABA applied every 24 hours for a total of 72 hours) on H2O2 content in Zea mays (maize) and to characterise genes encoding two putative maize RD22-like proteins (designated ZmRD22A and ZmRD22B)...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821526/development-and-testing-of-the-culture-of-care-barometer-cocb-in-healthcare-organisations-a-mixed-methods-study
#2
Anne Marie Rafferty, Julia Philippou, Joanne M Fitzpatrick, Geoff Pike, Jane Ball
OBJECTIVE: Concerns about care quality have prompted calls to create workplace cultures conducive to high-quality, safe and compassionate care and to provide a supportive environment in which staff can operate effectively. How healthcare organisations assess their culture of care is an important first step in creating such cultures. This article reports on the development and validation of a tool, the Culture of Care Barometer, designed to assess perceptions of a caring culture among healthcare workers preliminary to culture change...
August 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28821507/social-capital-neighbourhood-characteristics-and-utilisation-of-local-public-health-services-among-domestic-migrants-in-china-a-cross-sectional-study
#3
Zhiyuan Hou, Senlin Lin, Donglan Zhang
OBJECTIVES: We examined the association between structural social capital and public health services use, and explored the modifiable effect of neighbourhood factors on this association among domestic migrants in China. METHODS: Data were from a 2014 nationally representative cross-sectional sample of domestic migrants aged 15-59 years in China. Survey-weighted logistic regression models were applied to assess the association between structural social capital, measured by participation in social organisations and social activities, and use of public health services...
August 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28820231/interventions-for-treating-persistent-pain-in-survivors-of-torture
#4
REVIEW
Emma Baird, Amanda C de C Williams, Leslie Hearn, Kirstine Amris
BACKGROUND: Persistent (chronic) pain is a frequent complaint in survivors of torture, particularly but not exclusively pain in the musculoskeletal system. Torture survivors may have no access to health care; where they do, they may not be recognised when they present, and the care available often falls short of their needs. There is a tendency in state and non-governmental organisations' services to focus on mental health, with poor understanding of persistent pain, while survivors may have many other legal, welfare, and social problems that take precedence over health care...
August 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28816633/restoration-and-loss-after-disaster-applying-the-dual-process-model-of-coping-in-bereavement
#5
Ruth McManus, Tony Walter, Leon Claridge
The article asks whether disasters that destroy life but leave the material infrastructure relatively intact tend to prompt communal coping focussing on loss, while disasters that destroy significant material infrastructure tend to prompt coping through restoration / re-building. After comparing memorials to New Zealand's Christchurch earthquake and Pike River mine disasters, we outline circumstances in which collective restorative endeavour may be grassroots, organised from above, or manipulated, along with limits to effective restoration...
August 17, 2017: Death Studies
https://www.readbyqxmd.com/read/28815370/effects-of-small-hydropower-plants-on-mercury-concentrations-in-fish
#6
Elaine C Cebalho, Sergi Díez, Manoel Dos Santos Filho, Claumir Cesar Muniz, Wilkinson Lázaro, Olaf Malm, Aurea R A Ignácio
Although the impacts of large dams on freshwater biota are relatively well known, the effects of small hydropower plants (SHP) are not well investigated. In this work, we studied if mercury (Hg) concentrations in fish rise in two tropical SHP reservoirs, and whether similar effects take place during impoundment. Total Hg concentrations in several fish species were determined at two SHP in the Upper Guaporé River basin floodplain, Brazil. In total, 185 specimens were analysed for Hg content in dorsal muscle and none of them reported levels above the safety limit (500 μg kg(-1)) for fish consumption recommended by the World Health Organisation (WHO)...
August 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28814317/collaborative-care-for-panic-disorder-generalised-anxiety-disorder-and-social-phobia-in-general-practice-study-protocol-for-three-cluster-randomised-superiority-trials
#7
Nadja Kehler Curth, Ursula Ødum Brinck-Claussen, Annette Sofie Davidsen, Marianne Engelbrecht Lau, Merete Lundsteen, John Hagel Mikkelsen, Claudio Csillag, Carsten Hjorthøj, Merete Nordentoft, Lene Falgaard Eplov
BACKGROUND: People with anxiety disorders represent a significant part of a general practitioner's patient population. However, there are organisational obstacles for optimal treatment, such as a lack of coordination of illness management and limited access to evidence-based treatment such as cognitive behavioral therapy. A limited number of studies suggest that collaborative care has a positive effect on symptoms for people with anxiety disorders. However, most studies are carried out in the USA and none have reported results for social phobia or generalised anxiety disorder separately...
August 16, 2017: Trials
https://www.readbyqxmd.com/read/28812844/clinician-perspectives-of-barriers-to-effective-implementation-of-a-rapid-response-system-in-an-academic-health-centre-a-focus-group-study
#8
John Rihari-Thomas, Michelle DiGiacomo, Jane Phillips, Phillip Newton, Patricia M Davidson
BACKGROUND: Systemic and structural issues of rapid response system (RRS) models can hinder implementation. This study sought to understand the ways in which acute care clinicians (physicians and nurses) experience and negotiate care for deteriorating patients within the RRS. METHODS: Physicians and nurses working within an Australian academic health centre within a jurisdictional-based model of clinical governance participated in focus group interviews. Verbatim transcripts were analysed using thematic content analysis...
January 1, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812807/health-technology-assessment-global-advocacy-and-local-realities-comment-on-priority-setting-for-universal-health-coverage-we-need-evidence-informed-deliberative-processes-not-just-more-evidence-on-cost-effectiveness
#9
Kalipso Chalkidou, Ryan Li, Anthony J Culyer, Amanda Glassman, Karen J Hofman, Yot Teerawattananon
Cost-effectiveness analysis (CEA) can help countries attain and sustain universal health coverage (UHC), as long as it is context-specific and considered within deliberative processes at the country level. Institutionalising robust deliberative processes requires significant time and resources, however, and countries often begin by demanding evidence (including local CEA evidence as well as evidence about local values), whilst striving to strengthen the governance structures and technical capacities with which to generate, consider and act on such evidence...
August 29, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28808478/the-portuguese-long-version-of-the-copenhagen-psychosocial-questionnaire-ii-copsoq-ii-a-validation-study
#10
Susel Rosário, Luís F Azevedo, João A Fonseca, Albert Nienhaus, Matthias Nübling, José Torres da Costa
BACKGROUND: Psychosocial risks are now widely recognised as one of the biggest challenges for occupational safety and health (OSH) and a major public health concern. The aim of this paper is to investigate the Portuguese long version of the Copenhagen Psychosocial Questionnaire II (COPSOQ II), in order to analyse the psychometric properties of the instrument and to validate it. METHODS: The Portuguese COPSOQ II was issued to a total of 745 Portuguese employees from both private and public organisations across several economic sectors at a baseline and then 2 weeks later...
2017: Journal of Occupational Medicine and Toxicology
https://www.readbyqxmd.com/read/28807238/unravelling-the-complexity-of-signalling-networks-in-cancer-a-review-of-the-increasing-role-for-computational-modelling
#11
REVIEW
John Garland
Cancer induction is a highly complex process involving hundreds of different inducers but whose eventual outcome is the same. Clearly, it is essential to understand how signalling pathways and networks generated by these inducers interact to regulate cell behaviour and create the cancer phenotype. While enormous strides have been made in identifying key networking profiles, the amount of data generated far exceeds our ability to understand how it all "fits together". The number of potential interactions is astronomically large and requires novel approaches and extreme computation methods to dissect them out...
September 2017: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/28806822/-multiple-myeloma-current-status-in-diagnostic-testing-and-therapy
#12
Michael Kehrer, Sebastian Koob, Andreas Strauss, Dieter Christian Wirtz, Jan Schmolders
Background Multiple myeloma is a haematological blood cancer of the bone marrow and is classified by the World Health Organisation (WHO) as a plasma cell neoplasm. In multiple myeloma, normal plasma cells transform into malignant myeloma cells and produce large quantities of an abnormal immunoglobulin called monoclonal protein or M protein. This ultimately causes multiple myeloma symptoms such as bone damage or kidney problems. The annual worldwide incidence of multiple myeloma is estimated to be 6 - 7/100,000 and accounts for 1% of all cancer...
August 14, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28801403/equipping-community-pharmacy-workers-as-agents-for-health-behaviour-change-developing-and-testing-a-theory-based-smoking-cessation-intervention
#13
Liz Steed, Ratna Sohanpal, Wai-Yee James, Carol Rivas, Sandra Jumbe, Angel Chater, Adam Todd, Elizabeth Edwards, Virginia Macneil, Fraser Macfarlane, Trisha Greenhalgh, Chris Griffiths, Sandra Eldridge, Stephanie Taylor, Robert Walton
OBJECTIVE: To develop a complex intervention for community pharmacy staff to promote uptake of smoking cessation services and to increase quit rates. DESIGN: Following the Medical Research Council framework, we used a mixed-methods approach to develop, pilot and then refine the intervention. METHODS: Phase I: We used information from qualitative studies in pharmacies, systematic literature reviews and the Capability, Opportunity, Motivation-Behaviour framework to inform design of the initial version of the intervention...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28801396/the-sims-trial-adjustable-anchored-single-incision-mini-slings-versus-standard-tension-free-midurethral-slings-in-the-surgical-management-of-female-stress-urinary-incontinence-a-study-protocol-for-a-pragmatic-multicentre-non-inferiority-randomised-controlled
#14
Mohamed Abdel-Fattah, Graeme MacLennan, Mary Kilonzo, R Phil Assassa, Kirsty McCormick, Tracey Davidson, Alison McDonald, James N'Dow, Judith Wardle, John Norrie
INTRODUCTION: Single-incision mini-slings (SIMS) represent the third generation of midurethral slings. They have been developed with the aim of offering a true ambulatory procedure for treatment of female stress urinary incontinence (SUI) with reduced morbidity and earlier recovery while maintaining similar efficacy to standard midurethral slings (SMUS). The aim of this study is to determine the clinical and cost-effectiveness of adjustable anchored SIMS compared with tension-free SMUS in the surgical management of female SUI, with 3-year follow-up...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28799697/methylmalonate-semialdehyde-dehydrogenase-mediated-metabolite-homeostasis-essentially-regulate-conidiation-polarized-germination-and-pathogenesis-in-magnaporthe-oryzae
#15
Justice Norvienyeku, Zhenhui Zhong, Lili Lin, Xie Dang, Meilian Chen, Xiaolian Lin, Honghong Zhang, Wilfred Mabeche Anjago, Lianyu Lin, Waheed Abdul, Zonghua Wang
Plants generate multitude of aldehydes under abiotic and biotic stress conditions. Ample demonstrations have shown that rice-derived aldehydes enhance the resistance of rice against the rice-blast fungus Magnaporthe oryzae. However, how the fungal pathogen nullifies the inhibitory effects of host aldehydes to establish compatible interaction remains unknown. Here we identified and evaluated the in vivo transcriptional activities of M. oryzae aldehyde dehydrogenase (ALDH) genes. Transcriptional analysis of M...
August 11, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28798264/compliance-with-smoke-free-legislation-and-smoking-behaviour-observational-field-study-from-punjab-india
#16
Sonu Goel, Deepak Sharma, Rakesh Gupta, Vini Mahajan
BACKGROUND: Indian smoke-free legislation requires prohibition of smoking at public places and owners of public places to display 'no smoking' signages. AIMS AND OBJECTIVES: The study aims to assess the compliance of public places with smoke-free legislation and determine the factors associated with active smoking in public places. METHODOLOGY: This was a cross-sectional analytic observational quantitative survey conducted by a team of trained field investigators using a structured observational checklist across 6875 public places in Punjab state of India...
August 10, 2017: Tobacco Control
https://www.readbyqxmd.com/read/28798055/public-health-for-paediatricians-engaging-young-people-from-marginalised-groups
#17
Emma Rigby, Lindsay Starbuck
Young people from marginalised groups can be excluded from health services because of reduced access, increased stigma and health inequalities. In addition, the stress associated with discrimination and stigma can have serious effects on individual health. This article explores how stigma affects young people's access to services and how health professionals can improve their practice and support for marginalised young people to achieve the best possible health outcomes. A better understanding of local populations of young people and their needs is key to improving services and support...
August 10, 2017: Archives of Disease in Childhood. Education and Practice Edition
https://www.readbyqxmd.com/read/28797316/health-promotion-and-disease-prevention-in-general-practice-and-primary-care-a-scoping-study
#18
Stephen Peckham, Alison Hann, Sally Kendall, Steve Gillam
This paper reports the findings of a scoping review on the organisation and delivery of health improvement activities in general practice and the primary healthcare team. The project was designed to examine who delivers these interventions, where they are located, what approaches are developed in practices and how individual practices and the primary healthcare team organise such public health activities and how these contribute to health improvement. Our focus was on health promotion and prevention activities and aimed to identify the current extent of knowledge about the health improvement activities in general practice and the wider primary healthcare team...
August 11, 2017: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/28795905/challenges-in-preparing-veterinarians-for-global-animal-health-understanding-the-public-sector
#19
Paul J Hollier, Kaylee A Quinn, Corrie C Brown
Understanding of global systems is essential for veterinarians seeking to work in realms outside of their national domain. In the global system, emphasis remains on the public sector, and the current curricular emphasis in developed countries is on private clinical practice for the domestic employment market. There is a resulting lack of competency at graduation for effective engagement internationally. The World Organisation for Animal Health (OIE) has created standards for public sector operations in animal health, which must be functional to allow for sustainable development...
August 10, 2017: Journal of Veterinary Medical Education
https://www.readbyqxmd.com/read/28795474/endocrine-disruption-in-aquatic-systems-up-scaling-research-to-address-ecological-consequences
#20
Fredric M Windsor, Steve J Ormerod, Charles R Tyler
Endocrine-disrupting chemicals (EDCs) can alter biological function in organisms at environmentally relevant concentrations and are a significant threat to aquatic biodiversity, but there is little understanding of exposure consequences for populations, communities and ecosystems. The pervasive nature of EDCs within aquatic environments and their multiple sub-lethal effects make assessments of their impact especially important but also highly challenging. Herein, we review the data on EDC effects in aquatic systems focusing on studies assessing populations and ecosystems, and including how biotic and abiotic processes may affect, and be affected by, responses to EDCs...
August 9, 2017: Biological Reviews of the Cambridge Philosophical Society
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