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Frontal fibrosing alopecia

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https://www.readbyqxmd.com/read/29341265/cicatricial-alopecia-research-foundation-meeting-may-2016-progress-towards-the-diagnosis-treatment-and-cure-of-primary-cicatricial-alopecias
#1
John P Sundberg, Maria K Hordinsky, Wilma Bergfeld, Yolanda M Lenzy, Amy J McMichael, Angela M Christiano, Tracy McGregor, Kurt S Stenn, Raja K Sivamani, C Herbert Pratt, Lloyd E King
Primary Cicatricial Alopecias (PCAs) are a group of skin diseases in which there is progressive and permanent destruction of hair follicles followed by replacement with fibrous tissue. Unfortunately, by the time patients seek clinical evaluation of their hair loss, the skin is already inflamed and/or scarred, so there is little hope for a return to their normal hair growth pattern. Clinical and basic science investigations are now focusing on three forms of human PCA, lichen planopilaris (LPP), frontal fibrosing alopecia (FFA), and central centrifugal cicatricial alopecia (CCCA)...
January 16, 2018: Experimental Dermatology
https://www.readbyqxmd.com/read/29278862/frontal-fibrosing-alopecia-a-retrospective-analysis-of-72-patients-from-a-german-academic-center
#2
Markus V Heppt, Valerie Letulé, Ieva Laniauskaite, Markus Reinholz, Julia K Tietze, Hans Wolff, Thomas Ruzicka, Elke C Sattler
Frontal fibrosing alopecia (FFA) describes the scarring, band-like recession of the frontotemporal hairline. Treatment is difficult, and currently, no evidence-based therapy exists. The purpose of this study is to report clinical features and treatment responses in a large cohort of patients with FFA. The authors analyzed a series of 72 patients with a clinical or histologic diagnosis of FFA. A total of 70 patients were female (97.2%), and 2 were male (2.8%). In females, the first onset of FFA was postmenopausal in 81...
December 26, 2017: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/29241787/prognosis-treatment-and-disease-outcomes-in-frontal-fibrosing-alopecia-a-retrospective-review-of-92-cases
#3
Lauren C Strazzulla, Lorena Avila, Xiaoxue Li, Kristen Lo Sicco, Jerry Shapiro
No abstract text is available yet for this article.
January 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29224248/is-there-a-pathogenetic-link-between-frontal-fibrosing-alopecia-androgenetic-alopecia-and-fibrosing-alopecia-in-a-pattern-distribution
#4
A Katoulis, K Diamanti, D Sgouros, A I Liakou, E Bozi, G Avgerinou, I Panayiotides, D Rigopoulos
Frequent coexistence of frontal fibrosing alopecia (FFA) and androgenetic alopecia (AGA) has been reported in the literature, but little attention has been given to the pathogenetic mechanisms underlying this potential association. FFA is characterized by progressive cicatricial fronto-temporal hairline recession, mostly affecting peri-menopausal women. Immune mechanisms seem to play a pivotal pathogenetic role. This article is protected by copyright. All rights reserved.
December 10, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29177150/cutaneous-lupus-erythematosus-presenting-as-frontal-fibrosing-alopecia-report-of-2-patients
#5
Ralph M Trüeb, Laila El Shabrawi-Caelen, Werner Kempf
Frontal fibrosing alopecia represents a peculiar condition with a quasi-symmetrical, marginal scarring alopecia along the frontal and temporal hairline. The condition has been associated with further histopathologic and/or clinical evidence of lichen planopilaris. Since its emergence with the original report of Kossard in 1994, frontal fibrosing alopecia has been recognized to be associated with a number of comorbidities, including lupus erythematosus. So far, respective case reports and case series have given account of frontal fibrosing alopecia with the histopathologic features of lichen planopilaris associated or overlapping with lupus erythematosus...
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29177146/patchy-frontal-fibrosing-alopecia-description-of-an-incomplete-clinical-presentation
#6
Leticia Arsie Contin, Yana Lya de Almeida Ledá, Kédima Caldeira Nassif, Maria Victoria Suárez Restrepo
We describe 6 incomplete cases of frontal fibrosing alopecia (FFA). All patients were postmenopausal women. Their average age was 60 years; 2 of the women were Caucasian, and the remaining 4 women were of a mixed ethnicity. The disease duration ranged from 3 to 17 years. The patients' lesions presented as irregular alopecic plaques in the frontal and/or temporal regions, with few signs of perifollicular inflammation, slow progression, and progressive loss of the vellus hair in the frontal area. Loss of the eyebrows, facial hyperpigmentation, and loss of the body hair were observed in 3 patients, 1 patient, and 2 patients, respectively...
October 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29117306/frontal-fibrosing-alopecia-the-fashion-of-the-renaissance
#7
Gianluca Nazzaro, Stefano Veraldi
No abstract text is available yet for this article.
November 1, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/29104040/correction
#8
(no author information available yet)
No abstract text is available yet for this article.
November 8, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29076159/lichen-planus-pigmentosus-and-its-variants-review-and-update
#9
REVIEW
Juan Carlos Robles-Méndez, Paulina Rizo-Frías, Maira Elizabeth Herz-Ruelas, Amit G Pandya, Jorge Ocampo Candiani
Lichen planus pigmentosus (LPP) is considered a rare variant of lichen planus (LP). It is characterized by acquired dark brown to gray macular pigmentation located on sun-exposed areas of the face, neck, and flexures, commonly found in dark-skinned patients. In patients with LPP, an inflammatory lichenoid response results in marked pigmentary incontinence. It has been associated with hepatitis C virus, sun exposure, and contactants such as mustard oil and nickel. LPP-inversus affects fair and dark skin, predominantly involving flexural and intertriginous areas, while sun-exposed areas are spared; friction is an associated trigger...
October 26, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/29059513/the-increasing-incidence-of-frontal-fibrosing-alopecia-in-search-of-triggering-factors
#10
L Rudnicka, A Rakowska
No abstract text is available yet for this article.
October 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29056083/frontal-fibrosing-alopecia-update-and-review-of-challenges-and-successes
#11
Derek To, Jennifer Beecker
BACKGROUND: Frontal fibrosing alopecia (FFA) is a variant of lichen planopilaris (LPP) and is characterised as a progressive cicatricial alopecia affecting the frontotemporal hairline. OBJECTIVES: To perform a comprehensive, up-to-date review of the etiopathogenesis, clinicopathological features, and therapeutic options for FFA. METHODS: A literature search was conducted using PubMed (from 1946) and Cochrane (from 1991) databases on March 7, 2017...
October 1, 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29036252/efficacy-of-isotretinoin-and-acitretin-in-treatment-of-frontal-fibrosing-alopecia-retrospective-analysis-of-54-cases
#12
Adriana Rakowska, Agnieszka Gradzińska, Małgorzata Olszewska, Lidia Rudnicka
This study aimed to assess the efficacy of systemic retinoids in treating frontal fibrosing alopecia (FFA). It was based on a retrospective analysis of 54 female patients with FFA treated with: oral isotretinoin at the daily dose of 20 mg (29/54) or acitretin at the daily dose of 20 mg (11/54) or with oral finasteride 5 mg/daily (14/54). The study was conducted between 2007 and 2017. The basic of the study is the measurement of distance between the frontal hairline and the glabellar crease prior to the commencement of treatment and after 6, 12, and 24 months...
October 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29029919/the-doll-hairline-a-clue-for-the-diagnosis-of-frontal-fibrosing-alopecia
#13
Nicolò Brandi, Michela Starace, Aurora Alessandrini, Francesca Bruni, Bianca Maria Piraccini
No abstract text is available yet for this article.
November 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28947289/development-and-validation-of-the-frontal-fibrosing-alopecia-severity-score
#14
D Saceda-Corralo, O M Moreno-Arrones, P Fonda-Pascual, C Pindado-Ortega, D Buendía-Castaño, A Alegre-Sánchez, G Segurado-Miravalles, A R Rodrigues-Barata, P Jaén-Olasolo, S Vaño-Galván
No abstract text is available yet for this article.
September 22, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28932068/familial-cicatricial-alopecia-report-of-familial-frontal-fibrosing-alopecia-and-fibrosing-alopecia-in-a-pattern-distribution
#15
Dandara Meurer Missio, Maria Fernanda Reis Gavazzoni Dias, Ralph Michel Trüeb
Frontal fibrosing alopecia (FFA) and fibrosing alopecia in a pattern distribution (FAPD) as originally reported by Kossard in 1994 and by Zinkernagel and Trüeb in 2000, respectively, represent two distinct patterns of cicatricial pattern hair loss. Both share a patterned distribution and histological evidence of a lichenoid follicular inflammation with fibrosis. FFA is characterized by a marginal alopecia along the frontotemporal hairline, and FAPD by a progressive alopecia of the centroparietal scalp. Since the original reports, evidence has accumulated that there exists considerable clinical overlap among FFA, FAPD, and lichen planopilaris, with coexistence of features of the three conditions within the same individual...
July 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/28917459/yellow-facial-papules-associated-with-frontal-fibrosing-alopecia-a-distinct-histologic-pattern-and-response-to-isotretinoin
#16
LETTER
Ana Filipa Pedrosa, Ana Filipa Duarte, Eckart Haneke, Osvaldo Correia
No abstract text is available yet for this article.
October 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28879190/primary-scarring-alopecia-clinical-pathological-review-of-72-cases-and-review-of-the-literature
#17
Salvador Villablanca, Cristián Fischer, S Cecilia García-García, J Manuel Mascaró-Galy, Juan Ferrando
PURPOSE OF THE STUDY: To analyze the epidemiologic, demographic, clinical, and histological characteristics of primary scarring alopecia (PSA) cases diagnosed over a 7-year period at the Department of Dermatology, Hospital Clinic, Barcelona, Spain. PROCEDURES: Seventy-two patients diagnosed with PSA between 2006 and 2012 were included. Age, sex, ethnic group, clinical pattern, predominant histological infiltrate, final clinical diagnosis, time of onset, treatments used, and clinical evolution were evaluated and correlated...
August 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/28879188/the-use-of-direct-immunofluorescence-in-frontal-fibrosing-alopecia
#18
Aline Donati, Aditya K Gupta, Carolina Jacob, Benedicte Cavelier-Balloy, Pascal Reygagne
BACKGROUND: Frontal fibrosing alopecia (FFA) differs from lichen planopilaris (LPP) in many clinical aspects, but histology fails to distinguish between these entities. Direct immunofluorescence (DIF) is a diagnostic technique used for autoimmune diseases, including those affecting skin and hair. OBJECTIVE: To characterize DIF patterns in patients with FFA. METHOD: Data was collected retrospectively from FFA cases presenting to the Centre de Santé Sabouraud Hair Clinic in Paris from November 2013 to November 2014...
August 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/28859221/optical-coherence-tomography-for-the-investigation-of-frontal-fibrosing-alopecia
#19
Norma Elizabeth Vazquez-Herrera, Ariel E Eber, Maria Abril Martinez-Velasco, Marina Perper, Jessica Cervantes, Sebastian H Verne, Robert J Magno, Keyvan Nouri, Antonella Tosti
BACKGROUND: FFA is a cicatricial alopecia that affects the frontotemporal hairline, eyebrows, and body hair. OCT is a non-invasive imaging technique useful in understanding skin architecture and vascularization. OBJECTIVE: To describe structural and vascular findings in FFA using OCT. METHODS: This was a case-control study conducted from the months of December 2016-February 2017. The study was IRB approved and conducted at the University of Miami Hospital outpatient dermatology hair and nail clinic in Miami, FL...
August 31, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28774594/tissue-and-circulating-microrna-co-expression-analysis-shows-potential-involvement-of-mirnas-in-the-pathobiology-of%C3%A2-frontal-fibrosing-alopecia
#20
Christos Tziotzios, Chrysanthi Ainali, Susan Holmes, Fiona Cunningham, Su M Lwin, Ioulios Palamaras, Kapil Bhargava, Janice Rymer, Catherine M Stefanato, Niall Kirkpatrick, Sergio Vano-Galvan, Christos Petridis, David A Fenton, Michael A Simpson, Alexandros Onoufriadis, John A McGrath
No abstract text is available yet for this article.
November 2017: Journal of Investigative Dermatology
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