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Elizabeth V Saarel, Suzanne Granger, Jonathan R Kaltman, L LuAnn Minich, Martin Tristani-Firouzi, Jeffrey J Kim, Kathleen Ash, Sabrina S Tsao, Charles I Berul, Elizabeth A Stephenson, David G Gamboa, Felicia Trachtenberg, Peter Fischbach, Victoria L Vetter, Richard J Czosek, Tiffanie R Johnson, Jack C Salerno, Nicole B Cain, Robert H Pass, Ilana Zeltser, Eric S Silver, Joshua R Kovach, Mark E Alexander
BACKGROUND: Interpretation of pediatric ECGs is limited by lack of accurate sex- and race-specific normal reference values obtained with modern technology for all ages. We sought to obtain contemporary digital ECG measurements in healthy children from North America, to evaluate the effects of sex and race, and to compare our results to commonly used published datasets. METHODS: Digital ECGs (12-lead) were retrospectively collected for children ≤18 years old with normal echocardiograms at 19 centers in the Pediatric Heart Network...
July 2018: Circulation. Arrhythmia and Electrophysiology
Jin Jing, Susan Thapa, Leanna Delhey, Saly Abouelenein, Wesam Morad, Robert Delongchamp, Mohammed F Faramawi
The QRS-T angle is a key ECG predictor for ventricular arrhythmia. Lead has a strong relation with cardiovascular diseases; however, no study has been conducted to investigate the association between lead exposure and QRS-T angle. Thus, we explored this association in a population-based representative sample: NHANES III. We used the standard 12-lead ECGs to calculate Spatial QRS-T angles. Blood lead concentrations were measured using graphite furnace atomic absorption spectrophotometry method. We conducted multivariate weighted logistic regression to adjust for impaired fasting glucose, hypertension, poverty index, age, race, and smoking status...
June 19, 2018: Archives of Environmental & Occupational Health
Anna M Kaleta, Ewa Lewicka, Alicja Dąbrowska-Kugacka, Zuzanna Lewicka-Potocka, Elżbieta Wabich, Anna Szerszyńska, Julia Dyda, Jakub Sobolewski, Jakub Koenner, Grzegorz Raczak
BACKGROUND: Sports activity has become extremely popular among amateurs. Electrocardiography is a useful tool in screening for cardiac pathologies in athletes; however, there is little data on electrocardiographic abnormalities in the group of amateur athletes. OBJECTIVES: The aim of this study was to analyze the abnormalities in resting and exercise electrocardiograms (ECGs) in a group of amateur athletes, and try to determine whether the criteria applied for the general population or for athletes' ECGs should be implemented in this group...
June 18, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
David Andreu, Juan Fernández-Armenta, Juan Acosta, Diego Penela, Beatriz Jáuregui, David Soto-Iglesias, Vladimir Syrovnev, Elena Arbelo, José María Tolosana, Antonio Berruezo
BACKGROUND: Previously proposed algorithms to predict the ventricular tachycardia (VT) exit site have been based on diverse left ventricle (LV) models, but none of them identify the precise region of origin on electroanatomical mapping (EAM). Moreover, no ECG algorithm has been tested to predict the region of origin of scar-related VTs in non-ischemic patients. OBJECTIVE: To validate a simple electrocardiographic algorithm to identify the segment of origin (SgO) VT relative to the 17-segment American Heart Association (AHA) model in patients with structural heart disease (SHD)...
June 11, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Wei-Fong Kao, Sen-Kuang Hou, Chun-Yao Huang, Chun-Chieh Chao, Chung-Chih Cheng, Yi-Jung Chen
Atrial fibrillation (AF) is the most common arrhythmia. The most common diagnostic method, 12-lead electrocardiogram (ECG), can record episodes of arrhythmia from which the type and severity can be determined. The Heart Spectrum Blood Pressure Monitor (P2; OSTAR Meditech Corp., New Taipei City, Taiwan) is used to measure cardiovascular pressure change with fast Fourier transform (FFT) analysis to obtain heart rate frequency variability and accurate blood pressure data. We compared the diagnostic efficacy of the Heart Spectrum Blood Pressure Monitor to a 12-lead ECG (gold standard) for patients with AF...
2018: PloS One
Alev Kılıcgedik, Abdulrahman Naser, Ahmet Seyfeddin Gurbuz, Seyhmus Kulahcioglu, Ruken Bengi Bakal, Tuba Unkun, Fatih Yilmaz, Gokhan Kahveci, Cevat Kirma
BACKGROUND: The use of the CHA2DS2-VASc scoring system and red cell distribution width (RDW) as post-op Atrial Fibrillation (POAF) predictors may be promising for the identification of patients that are at a higher risk of POAF. METHODS: A total of 358 patients (57 patients with POAF, and 301 patients with non-POAF ) with sinus rhythm undergoing a coronary artery bypass graft (CABG) operation were included in the study retrospectively. Preoperative RDW levels and electrocardiograms with sinus rhythm were recorded...
May 16, 2018: Heart Surgery Forum
Silvia Castelletti, Federica Dagradi, Karine Goulene, Aurora I Danza, Enrico Baldi, Marco Stramba-Badiale, Peter J Schwartz
BACKGROUND: A correct measurement of the QT interval in the out-of-hospital setting is important whenever the long QT syndrome (LQTS) is suspected or a therapy might lead to drug-induced LQTS (diLQTS) because QT interval monitoring in the initial days of therapy could alert to dangerous QT prolongation. We explored whether automated QTc measurements (BGM) by BodyGuardian™ (BG), a wearable remote monitoring system, are sufficiently reliable compared to our own manual measurements (MM) performed on the same beats during 12‑lead Holter recordings in LQTS patients (pts) and in healthy controls...
September 1, 2018: International Journal of Cardiology
Stefanie Aeschbacher, Wesley T O'Neal, Philipp Krisai, Laura Loehr, Lin Y Chen, Alvaro Alonso, Elsayed Z Soliman, David Conen
BACKGROUND: QRS duration (QRSd), a measure of ventricular conduction, has been associated with adverse cardiovascular outcomes, but its relationship with incident atrial fibrillation (AF) is poorly understood. METHODS AND RESULTS: This study included 15,314 participants from the Atherosclerosis Risk in Communities (ARIC) study who were free of AF at baseline. QRSd was automatically measured from resting 12-lead electrocardiograms (ECGs) at baseline. Incident AF cases were systematically ascertained using ECGs, hospital discharge diagnoses and death certificates...
September 1, 2018: International Journal of Cardiology
Alessandro Zorzi, Manuel De Lazzari, Giulio Mastella, Alice Niero, Domenico Trovato, Alberto Cipriani, Francesco Peruzza, Leonardo Portolan, Giampaolo Berton, Federco Sciacca, Saverio Tollot, Chiara Palermo, Roberto Bellu, Flavio D'ascenzi, Denisa Muraru, Luigi Paolo Badano, Sabino Iliceto, Maurizio Schiavon, Martina Perazzolo Marra, Domenico Corrado
BACKGROUND: Whether ventricular arrhythmias (VAs) represent a feature of the adaptive changes of the athlete's heart remains elusive. We aimed to assess the prevalence, determinants, and underlying substrates of VAs in young competitive athletes. METHOD AND RESULTS: We studied 288 competitive athletes (age range, 16-35 years; median age, 21 years) and 144 sedentary individuals matched for age and sex who underwent 12-lead 24-hour ambulatory electrocardiographic monitoring...
June 9, 2018: Journal of the American Heart Association
Kirian van der Weg, Wichert J Kuijt, Sebastiaan C A M Bekkers, Jan G P Tijssen, Cynthia L Green, Martijn W Smulders, Miguel E Lemmert, Mitchell W Krucoff, Anton P M Gorgels
BACKGROUND: The presence of reperfusion ventricular arrhythmias (VA) has been shown to correlate with larger infarct size (IS). However it is unclear whether the initial area at risk (AAR), also a determining factor for IS, is responsible for this correlation. We hypothesized that IS would be significantly larger in the presence of VA, while AAR would not differ. METHODS: 68 STEMI patients from the MAST study with 24-hour, continuous, 12‑lead Holter monitoring initiated prior to primary percutaneous coronary intervention (PCI) resulting in TIMI 3 flow post PCI were included...
May 30, 2018: International Journal of Cardiology
Zhi-Zhao Li, Xin Du, Xue-Yuan Guo, Ri-Bo Tang, Chao Jiang, Nian Liu, San-Shuai Chang, Rong-Hui Yu, De-Yong Long, Rong Bai, Cai-Hua Sang, Song-Nan Li, Jian-Zeng Dong, Chang-Sheng Ma
BACKGROUND Dyslipidemia is the most frequent comorbidity in patients with cardiovascular disease. However, studies examining the relationship between blood lipid profiles and AF have produced inconsistent results. MATERIAL AND METHODS A total of 651 patients were enrolled into 3 groups: Healthy controls (n=64), Paroxysmal AF (PAF; n=270), and Continuous AF (CAF; n=317). All enrolled patients underwent routine baseline 12-lead electrocardiography (ECG) and 24-h dynamic ECG along with blood testing, which included the following: complete metabolic panel, hepatic function, renal function, circulating thyroxine, fasting high-density lipoprotein cholesterol (HDL -C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), and total cholesterol (TC)...
June 9, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Jeong Gyu Kang, Yoosoo Chang, Ki-Chul Sung, Jang-Young Kim, Hocheol Shin, Seungho Ryu
The aim of this study was to examine the associations of isolated minor nonspecific ST-T abnormalities (NSSTTA) on 12-lead electrocardiogram (ECG) with left ventricular (LV) diastolic function and LV geometry on echocardiography. A cross-sectional study comprised of 74,976 Koreans who underwent ECG and echocardiography as part of a comprehensive health examination between March 2011 and December 2014. ECG was coded using Minnesota Code criteria. The frequencies of NSSTTA, impaired LV relaxation, and echocardiographic LVH were 1,139 (1...
June 8, 2018: Scientific Reports
Borje Darpo, Jean-Philippe Couderc
INTRODUCTION: This paper is based on a presentation held at the Annual Safety Pharmacology Society meeting in September 2017, at which challenges for the clinical component of CiPA were presented. FDA has published an automated algorithm for measurement of the J-Tpeak interval on a median beat from a vector magnitude lead derived from a 12-lead ECG. CiPA proposes that J-Tpeak prolongation < 10 ms can be used for drugs with a QTc effect < 20 ms to differentiate between safe and unsafe delayed repolarization and to reduce the level of ECG monitoring in late stage clinical trials...
June 4, 2018: Journal of Pharmacological and Toxicological Methods
Meiwei Zhang, Yeling Wang, Dongmei Chen, Hang Li, Zhiguo Zhang
RATIONALE: Dual atrioventricular nodal non-reentrant tachycardia (DAVNNT) is an uncommon arrhythmia. Because of the different refractory periods of fast and slow pathways, a single atrial depolarization gives rise to 2 ventricular activationsthrough fast and slow pathways separately. PATIENT CONCERNS: A 45-year-old woman was referred to our Cardiology Center with symptoms of recurrent palpitations and fatigue persisting for the previous 3 years. On echocardiography, the ejection fraction of the left ventricle was 45%...
June 2018: Medicine (Baltimore)
Yoshihiro Kimura, Masahiro Yamada, Kenji Hanada, Tomohide Endo, Noritomo Narita, Masato Narita, Maiko Senoo, Manabu Yonekura, Hiroaki Ichikawa, Shizuka Kurauchi, Shigeyuki Nakaji, Ken Okumura, Hirofumi Tomita
We previously showed that J-waves were found more frequently in patients with low levels of serum eicosapentaenoic acid (EPA) in the acute phase of myocardial infarction, and were associated with the incidence of ischemia-related ventricular arrhythmias. However, the relationship between J-waves and serum EPA levels in a general population remains to be elucidated.The Iwaki Health Promotion Project is an ongoing community-based health promotion study in Iwaki, Hirosaki, which is in northern Japan. A total of 1,052 residents (mean age, 53...
June 6, 2018: International Heart Journal
Maria A Baturova, Valentina Kutyifa, Scott McNitt, Bronislava Polonsky, Scott Solomon, Jonas Carlson, Wojciech Zareba, Pyotr G Platonov
Cardiac resynchronization therapy (CRT) has proven prognostic benefits in patients with heart failure (HF) with left bundle branch block (LBBB) QRS morphology. Electrocardiographic left atrial (LA) abnormality has been proposed as a noninvasive marker of atrial remodeling. We aimed to assess the impact of electrocardiographic LA abnormality for prognosis in patients with HF treated with CRT. Baseline resting 12-lead electrocardiograms recorded from 941 patients enrolled in the CRT arm of the Multicenter Automatic Defibrillator Implantation Trial with Cardiac Resynchronization Therapy was processed automatically using Glasgow algorithm, which included automated assessment of P-wave terminal force in lead V1 (PTF-V1 ) as a marker of LA abnormality...
April 11, 2018: American Journal of Cardiology
Rahul G Muthalaly, Bruce A Koplan, Alfred Albano, Crystal North, Jeffrey I Campbell, Bernard Kakuhikire, Dagmar Vořechovská, John D Kraemer, Alexander C Tsai, Mark J Siedner
OBJECTIVES: Atrial fibrillation (AF) is a major risk factor for stroke, which is the leading cause of cardiovascular mortality in sub-Saharan Africa. However, there is limited population-based epidemiological data on AF in sub-Saharan Africa. We sought to estimate the prevalence and correlates of AF in rural Uganda. METHODS: We conducted a cross-sectional study using community health fairs in 2015 targeting eight villages in rural Uganda. Study participants completed a medical history, a clinical exam, blood collection, and 12‑lead electrocardiographic (ECG) screening...
May 24, 2018: International Journal of Cardiology
Chin-Wei W Huang, Suzan Brown, Neelan Pillay, Martin Del Campo, Jose Tellez-Zenteno, Richard S McLachlan
PURPOSE: Lacosamide selectively enhances slow inactivation of voltage-gated sodium channels to achieve seizure reduction. We studied the effect of intravenous lacosamide given as one of three single doses on EEG and electrocardiogram, as well as its tolerability in patients with drug-resistant epilepsy. METHODS: This Canadian, investigator-initiated, multicenter, double-blind study recruited patients with refractory focal epilepsy admitted to a seizure monitoring unit...
May 30, 2018: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
Alexander Chiu, Michael Kasper, John Rimmer, Meaghan Donnelly, Yangmin Chen, Caroline Chau, Lauren Sidow, Adam Ash
We report a case of new-onset atrial fibrillation with rapid ventricular response in a 37-year-old male who presented to the emergency department. This patient was not admitted to the hospital or placed on observation, but rather placed on a cellular outpatient 12-lead telemetry (COTLT) device with emergency response capabilities and discharged home. We define a new modality that allows these patients to be managed via telemedicine and receive care similar to that which would be rendered in a hospital or observation unit...
August 2017: Clinical practice and cases in emergency medicine
Mücahid Yılmaz, Hidayet Kayançiçek
OBJECTIVES: Intense exercise elevates all heart chambers' dimensions, left ventricular mass (LV mass), and left ventricular mass index (LV mass index). The relationship between increased ventricular arrhythmias and sudden cardiac death with LV dilatation and elevated LV mass has been previously demonstrated. We investigated whether sports-related LV dilatation and elevated LV mass and LV mass index cause an increase in ventricular repolarization heterogeneity. PATIENTS AND METHODS: This prospective observational study recruited 565 participants...
May 28, 2018: Journal of Clinical Medicine
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