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A I Parfenov, I N Ruchkina, R I Ataullakhanov, O F Belaia, B Z Chikunova, A V Pichugin, E Sh Kozhemiakina
AIM: To characterize pathogenesis, clinicolaboratory criteria and treatment of postinfection irritable bowel syndrome (PICS). MATERIAL AND METHODS: The examination including histological study of the small and large intestine mucosa, polymerase chain reaction (PCR), coagglutination reaction using shigella, salmonella, yersinia, campilobacter jejuni diagnosticums, indirect hemagglutination reaction for identification of antibodies to these agents in the blood serum was conducted in 750 patients with PICS...
2009: Terapevticheskiĭ Arkhiv
Yu-xing Gao, Shu-lan Li, Xiu-zhen Han, Yan Sun, Chun-mei Yao
OBJECTIVE: To explore the therapeutic mechanisms of interferon-beta (IFN-beta) and intravenous immunoglobulin (IVIG) for experimental peripheral neuropathy induced by Campilobacter jejuni (Cj) lipopolysaccharide (LPS). METHOD: Forty healthy Wistar rats weighing 205 - 230 g were divided into IFN-beta, IVIG, IFN-beta plus IVIG and control groups. After the immune neuropathy was induced in the rats by Cj LPS, IFN-beta (1.3 microg/kg) was given by subcutaneous injection to the rats every other day for 6 weeks; IVIG [400 mg/(kg x d)] was given to the rats for five days, every other week for two times and IFN-beta [1...
August 2007: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
V A Kalashnikova, E K Dzhikidze, Z K Stasilevich, R I Krylova, T I Kebu
The subjects of the study were 1,249 primates of different species, kept in a nursery in the city of Adler. The subjects varied in age, were either clinically healthy, diseased, or dead (the death had been caused by an acute intestinal disease). Biological, molecular-genetic (PCR), and immunological (coagglutination reaction) methods were used in diagnostics of campilobacter infections. The study found campilobacter in 20.9% of healthy animals on the average; this number varied depending on the species and age...
2006: Vestnik Rossiĭskoĭ Akademii Meditsinskikh Nauk
Rusmir Mesihović
Since 1874, possibility of gastric mucosa infection was discussed as a cause of ulcer forming. In 1893 spirochette in gastric mucosa of animals were described. In 1940 bacteria in gastric mucosa of patients with ulcers and cancers were found. In 1983, a new era in gastroenterology begun with synchronic discoveries of bacterial etiology of chronic gastritis and ulcer disease. Australian scientists Barry Marshall and Robin Warren were the first who publisher results about relations between gastric mucosa spiral microorganisms and chronic gastritis...
2003: Medicinski Arhiv
H J Snijder, I Ubarretxena-Belandia, M Blaauw, K H Kalk, H M Verheij, M R Egmond, N Dekker, B W Dijkstra
Dimerization is a biological regulatory mechanism employed by both soluble and membrane proteins. However, there are few structural data on the factors that govern dimerization of membrane proteins. Outer membrane phospholipase A (OMPLA) is an integral membrane enzyme which participates in secretion of colicins in Escherichia coli. In Campilobacter and Helicobacter pylori strains, OMPLA is implied in virulence. Its activity is regulated by reversible dimerization. Here we report X-ray structures of monomeric and dimeric OMPLA from E...
October 14, 1999: Nature
I A Guseva, J Uksila, Sh Erdes, R Toivanen, L I Benevolenskaia
The paper presents the results of the study of specific immune response stimulated by some enterobacteria in populations with high incidence of HLA-B27. A, M and G antibodies to Yersinia, Clebsiella, Salmonella and Campilobacter were studied on 292 plasma samples. The levels of the antibodies varied with anthropological parameters of the examinees (gender, age, nationality). The presence of the gene HLA-B27 in the genotype levels gender dimorphism of the specific humoral immune response. This may be of importance in pathogenesis of spondyloarthropathies which occur more frequently in men...
1999: Klinicheskaia Meditsina
M Averbach, R Cutait, P Corrêa, M I Duarte, K Leite, J L Borges
In order to establish which are the most frequent endoscopic detectable colorectal disorders in AIDS patients with intestinal complaints we analysed 236 colonoscopies in a series of 186 patients. The colonoscopic procedure was always followed by biopsies, even in the absence of macroscopic lesions. The most frequent diagnosis was colitis due to citomegalovirus infection observed in 64 exams (27.1%) and presented with an inflammatory pattern with ulcers, followed by Cryptosporidium sp., found in 31 exams (13...
April 1998: Arquivos de Gastroenterologia
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