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https://www.readbyqxmd.com/read/28929446/new-imaging-tools-in-cardiovascular-medicine-computational-fluid-dynamics-and-4d-flow-mri
#1
Keiichi Itatani, Shohei Miyazaki, Tokoki Furusawa, Satoshi Numata, Sachiko Yamazaki, Kazuki Morimoto, Rina Makino, Hiroko Morichi, Teruyasu Nishino, Hitoshi Yaku
Blood flow imaging is a novel technology in cardiovascular medicine and surgery. Today, two types of blood flow imaging tools are available: measurement-based flow visualization including 4D flow MRI (or 3D cine phase-contrast magnetic resonance imaging), or echocardiography flow visualization software, and computer flow simulation modeling based on computational fluid dynamics (CFD). MRI and echocardiography flow visualization provide measured blood flow but have limitations in temporal and spatial resolution, whereas CFD flow calculates the flow according to assumptions instead of flow measurement, and it has sufficiently fine resolution up to the computer memory limit, and it enables even virtual surgery when combined with computer graphics...
September 19, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28926132/prenatal-diagnosis-of-total-and-partial-anomalous-pulmonary-venous-connection-multicentre-cohort-study-and-meta-analysis
#2
REVIEW
Dario Paladini, Angela Pistorio, L H Wu, Gabriella Meccariello, Ting Lei, Giulia Tuo, Gloria Donarini, Maurizio Marasini, Hong-Ning Xie
OBJECTIVES: Aim of this study is to describe the sonographic features and associations of Total and Partial Anomalous Pulmonary Venous Connection (TAPVC, PAPVC) and scimitar syndrome (SS) and to review the relevant literature systematically in order to underline the associations and the sonographic features more frequently associated with these conditions. METHODOLOGY: Retrospective cohort study. Assessed variables include: TAPVC subtype, gestational age at diagnosis, area behind LA, ventricular disproportion, vertical vein, pulmonary venous obstruction, mode of diagnosis, association with cardiac and extra-cardiac conditions, pregnancy and feto-neonatal outcome...
September 19, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28833523/modeling-of-coarctation-of-aorta-in-human-fetuses-using-3d-4d-fetal-echocardiography-and-computational-fluid-dynamics
#3
Zhuo Chen, Yue Zhou, Jingying Wang, Xiaowei Liu, Shuping Ge, Yihua He
OBJECTIVES: We sought to develop a hemodynamic model of aortic and ductal arches using computational fluid dynamics (CFD) and 3D/4D spatio-temporal image correlation (STIC) fetal echocardiography and to investigate the hemodynamics of coarctation of aorta (CoA) in human fetuses using this approach. METHODS: We obtained 3D/4D STIC fetal echocardiographic images of the aortic and ductal arches (DA) in five normal fetuses. Based on these images, we simulated the hemodynamics in the two arches using CFD...
August 22, 2017: Echocardiography
https://www.readbyqxmd.com/read/28803252/two-dimensional-echocardiography-estimates-of-fetal-ventricular-mass-throughout-gestation
#4
Christina Y L Aye, Adam James Lewandowski, Eric O Ohuma, Ross Upton, Alice Packham, Yvonne Kenworthy, Fenella Roseman, Tess Norris, Malid Molloholli, Sikolia Wanyonyi, Aris T Papageorghiou, Paul Leeson
BACKGROUND: Two-dimensional (2D) ultrasound quality has improved in recent years. Quantification of cardiac dimensions is important to screen and monitor certain fetal conditions. We assessed the feasibility and reproducibility of fetal ventricular measures using 2D echocardiography, reported normal ranges in our cohort, and compared estimates to other modalities. METHODS: Mass and end-diastolic volume were estimated by manual contouring in the four-chamber view using TomTec Image Arena 4...
August 12, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28783626/fast-and-fully-automatic-left-ventricular-segmentation-and-tracking-in-echocardiography-using-shape-based-b-spline-explicit-active-surfaces
#5
Joao Pedrosa, Sandro Queiros, Olivier Bernard, Jan Engvall, Thor Edvardsen, Eike Nagel, Jan Dhooge
Cardiac volume/function assessment remains a critical step in daily cardiology and 3D ultrasound plays an increasingly important role. Fully automatic left ventricular segmentation is, however, a challenging task due to the artifacts and low contrast-to-noise ratio of ultrasound imaging. In the present work, a fast and fully automatic framework for full cycle endocardial left ventricle segmentation is proposed. This approach couples the advantages of the B-spline explicit active surfaces framework, a purely image information approach, to those of statistical shape models to give prior information about the expected shape for an accurate segmentation...
August 2, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28742031/patient-specific-left-ventricular-flow-simulations-from-transthoracic-echocardiography-robustness-evaluation-and-validation-against-ultrasound-doppler-and-magnetic-resonance-imaging
#6
David Larsson, Jeannette H Spuhler, Sven Petersson, Tim Nordenfur, Massimiliano Colarieti-Tosti, Johan Hoffman, Reidar Winter, Matilda Larsson
The combination of medical imaging with computational fluid dynamics (CFD) has enabled the study of 3D blood flow on a patient-specific level. However, with models based on gated high-resolution data, the study of transient flows, and any model implementation into routine cardiac care, is challenging. The present paper presents a novel pathway for patient-specific CFD modelling of the left ventricle (LV), using 4D transthoracic echocardiography (TTE) as input modality. To evaluate the clinical usability, two sub-studies were performed...
July 21, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28711164/on-estimating-intraventricular-hemodynamic-forces-from-endocardial-dynamics-a-comparative-study-with-4d-flow-mri
#7
Gianni Pedrizzetti, Per M Arvidsson, Johannes Töger, Rasmus Borgquist, Federico Domenichini, Håkan Arheden, Einar Heiberg
Intraventricular pressure gradients or hemodynamic forces, which are their global measure integrated over the left ventricular volume, have a fundamental importance in ventricular function. They may help revealing a sub-optimal cardiac function that is not evident in terms of tissue motion, which is naturally heterogeneous and variable, and can influence cardiac adaptation. However, hemodynamic forces are not utilized in clinical cardiology due to the unavailability of simple non-invasive measurement tools...
July 26, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28688483/imaging-of-heart-acoustic-based-on-the-sub-space-methods-using-a-microphone-array
#8
Hanie Moghaddasi, Farshad Almasganj, Arezoo Zoroufian
BACKGROUND AND OBJECTIVES: Heart disease is one of the leading causes of death around the world. Phonocardiogram (PCG) is an important bio-signal which represents the acoustic activity of heart, typically without any spatiotemporal information of the involved acoustic sources. The aim of this study is to analyze the PCG by employing a microphone array by which the heart internal sound sources could be localized, too. METHOD: In this paper, it is intended to propose a modality by which the locations of the active sources in the heart could also be investigated, during a cardiac cycle...
July 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28685315/clinical-feasibility-and-validation-of-3d-principal-strain-analysis-from-cine-mri-comparison-to-2d-strain-by-mri-and-3d-speckle-tracking-echocardiography
#9
Alessandro Satriano, Bobak Heydari, Mariam Narous, Derek V Exner, Yoko Mikami, Monica M Attwood, John V Tyberg, Carmen P Lydell, Andrew G Howarth, Nowell M Fine, James A White
Two-dimensional (2D) strain analysis is constrained by geometry-dependent reference directions of deformation (i.e. radial, circumferential, and longitudinal) following the assumption of cylindrical chamber architecture. Three-dimensional (3D) principal strain analysis may overcome such limitations by referencing intrinsic (i.e. principal) directions of deformation. This study aimed to demonstrate clinical feasibility of 3D principal strain analysis from routine 2D cine MRI with validation to strain from 2D tagged cine analysis and 3D speckle tracking echocardiography...
July 6, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28679680/chronic-hypoxia-alters-maternal-uterine-and-fetal-hemodynamics-in-the-term-pregnant-guinea-pig
#10
Shifa Turan, Graham W Aberdeen, Loren P Thompson
Placental hypoxia is associated with maternal hypertension, placental insufficiency and fetal growth restriction. In the pregnant guinea pig, prenatal hypoxia during early gestation inhibits cytotrophoblast invasion of spiral arteries, increases maternal blood pressure and induces fetal growth restriction. This study evaluated the impact of chronic maternal hypoxia on fetal heart structure with 4D echocardiography with spatio-temporal image correlation and tomographic ultrasound (STIC-TUI) and uterine and umbilical artery resistance/pulsatility indices and fetal heart function using pulsed wave Doppler ultrasound...
July 5, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28617686/imaging-adult-patients-with-coarctation-of-the-aorta
#11
Akanksha N Thakkar, Ponraj Chinnadurai, C Huie Lin
PURPOSE OF REVIEW: To provide an overview of current recommendations and techniques used to image coarctations of the aorta. RECENT FINDINGS: Imaging of coarctation of the aorta in adults is moving away from conventional techniques such as echocardiography and invasive angiography. Echocardiography may assist in making the diagnosis but is limited in its ability to quantify the severity of coarctations. Current guidelines recommend that every patient with a coarctation must undergo a computed tomography (CT) or MRI scan for accurate delineation of morphology...
June 15, 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/28611119/turbulent-kinetic-energy-assessed-by-multipoint-4-dimensional-flow-magnetic-resonance-imaging-provides-additional-information-relative-to-echocardiography-for-the-determination-of-aortic-stenosis-severity
#12
COMPARATIVE STUDY
Christian Binter, Alexander Gotschy, Simon H Sündermann, Michelle Frank, Felix C Tanner, Thomas F Lüscher, Robert Manka, Sebastian Kozerke
BACKGROUND: Turbulent kinetic energy (TKE), assessed by 4-dimensional (4D) flow magnetic resonance imaging, is a measure of energy loss in disturbed flow as it occurs, for instance, in aortic stenosis (AS). This work investigates the additional information provided by quantifying TKE for the assessment of AS severity in comparison to clinical echocardiographic measures. METHODS AND RESULTS: Fifty-one patients with AS (67±15 years, 20 female) and 10 healthy age-matched controls (69±5 years, 5 female) were prospectively enrolled to undergo multipoint 4D flow magnetic resonance imaging...
June 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28460004/4d-flow-cardiac-magnetic-resonance-derived-vorticity-is-sensitive-marker-of-left-ventricular-diastolic-dysfunction-in-patients-with-mild-to-moderate-chronic-obstructive-pulmonary-disease
#13
Michal Schäfer, Stephen Humphries, Kurt R Stenmark, Vitaly O Kheyfets, J Kern Buckner, Kendall S Hunter, Brett E Fenster
Aims: To investigate the possibility that vorticity assessed by four-dimensional flow cardiac magnetic resonance (4D-Flow CMR) in the left ventricle of patients with mild-to-moderate chronic obstructive pulmonary disease (COPD) is a potential marker of early LV diastolic dysfunction (LVDD) and more sensitive than standard echocardiography, and whether changes in vorticity are associated with quantitative computed tomography (CT) and clinical markers of COPD, and right ventricular (RV) echocardiographic markers indicative of ventricular interdependency...
April 27, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28401632/role-of-four-dimensional-echocardiography-with-high-definition-flow-imaging-and-spatiotemporal-image-correlation-in-detecting-fetal-pulmonary-veins
#14
Xue Sun, Ying Zhang, Miao Fan, Yu Wang, Meilian Wang, Faiza Amber Siddiqui, Wei Sun, Feifei Sun, Dongyu Zhang, Wenjia Lei, Guyue Hu
BACKGROUND: Prenatal diagnosis of fetal total anomalous pulmonary vein connection (TAPVC) remains challenging for most screening sonographers. The purpose of this study was to evaluate the use of four-dimensional echocardiography with high-definition flow imaging and spatiotemporal image correlation (4D-HDFI) in identifying pulmonary veins in normal and TAPVC fetuses. MATERIAL & METHODS: We retrospectively reviewed and performed 4D-HDFI in 204 normal and 12 fetuses with confirmed diagnosis of TAPVC...
April 12, 2017: Echocardiography
https://www.readbyqxmd.com/read/28337810/electronic-stic-improves-four-dimensional-fetal-echocardiography
#15
F Guasina, F Bellussi, G Morganelli, G Salsi, G Pilu, G Simonazzi
OBJECTIVES: To compare the efficiency of electronic Spatio-Temporal Image Correlation (eSTIC) with conventional STIC to acquire fetal cardiac four-dimensional (4D) volumes of diagnostic quality METHODS: This was a randomized controlled trial of 100 patients at midgestation with normal sonograms. In half of the cases, STIC of the fetal heart were obtained with a conventional mechanical 4D probe, in the remaining eSTIC were obtained with an electronic 4D probe. Examinations were kept within the time frame allotted for a standard examination of fetal anatomy, with a maximum of 2 attempts at obtaining a 4D cardiac volume...
March 24, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28224424/dynamic-characteristic-mechanism-of-atrial-septal-defect-using-real-time-three-dimensional-echocardiography-and-evaluation-of-right-ventricular-functions
#16
Gao-Wa Sharen, Jun Zhang, Chuan Qin, Qing Lv
The dynamic characteristics of the area of the atrial septal defect (ASD) were evaluated using the technique of real-time three-dimensional echocardiography (RT 3DE), the potential factors responsible for the dynamic characteristics of the area of ASD were observed, and the overall and local volume and functions of the patients with ASD were measured. RT 3DE was performed on the 27 normal controls and 28 patients with ASD. Based on the three-dimensional data workstations, the area of ASD was measured at P wave vertex, R wave vertex, T wave starting point, and T wave terminal point and in the T-P section...
February 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/28134395/ultrasound-examination-of-the-fetal-heart
#17
Katherine C Bishop, Jeffrey A Kuller, Brita K Boyd, Eleanor H Rhee, Stephen Miller, Piers Barker
Congenital heart disease (CHD) occurs in 4-13 per 1000 births in the United States. While many risk factors for CHD have been identified, more than 90% of cases occur in low-risk patients. Guidelines for fetal cardiac screening during the second trimester anatomy ultrasound have been developed by the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) in order to improve antenatal detection rates and to standardize the fetal cardiac screening examination. Patients found to be at increased risk of CHD because of risk factors or an abnormal screening examination should be referred for second trimester fetal echocardiography...
January 2017: Obstetrical & Gynecological Survey
https://www.readbyqxmd.com/read/28113394/4d-ice-a-2d-array-transducer-with-integrated-asic-in-a-10-fr-catheter-for-real-time-3d-intracardiac-echocardiography
#18
Douglas Wildes, Warren Lee, Bruno Haider, Scott Cogan, Krishnakumar Sundaresan, David Mills, Christopher Yetter, Patrick Hart, Christopher Haun, Mikael Concepcion, Johan Kirkhorn, Marc Bitoun
We developed a 2.5 x 6.6 mm 2D array transducer with integrated transmit/receive ASIC for 4D ICE (real-time 3D IntraCardiac Echocardiography) applications. The ASIC and transducer design were optimized so that the high voltage transmit, low-voltage TGC (time-gain control) and preamp, subaperture beamformer, and digital control circuits for each transducer element all fit within the 0.019 mm2 area of the element. The transducer assembly was deployed in a 10 Fr (3.3 mm diameter) catheter, integrated with a GE Vivid1 E9 ultrasound imaging system, and evaluated in three pre-clinical studies...
October 12, 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/27740477/4-d-ice-a-2-d-array-transducer-with-integrated-asic-in-a-10-fr-catheter-for-real-time-3-d-intracardiac-echocardiography
#19
Douglas Wildes, Warren Lee, Bruno Haider, Scott Cogan, Krishnakumar Sundaresan, David M Mills, Christopher Yetter, Patrick H Hart, Christopher R Haun, Mikael Concepcion, Johan Kirkhorn, Marc Bitoun
We developed a 2.5 ×6.6 mm (2) 2 -D array transducer with integrated transmit/receive application-specific integrated circuit (ASIC) for real-time 3-D intracardiac echocardiography (4-D ICE) applications. The ASIC and transducer design were optimized so that the high-voltage transmit, low-voltage time-gain control and preamp, subaperture beamformer, and digital control circuits for each transducer element all fit within the 0.019-mm (2) area of the element. The transducer assembly was deployed in a 10-Fr (3...
December 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/27659876/hemodynamic-evaluation-in-patients-with-transposition-of-the-great-arteries-after-the-arterial-switch-operation-4d-flow-and-2d-phase-contrast-cardiovascular-magnetic-resonance-compared-with-doppler-echocardiography
#20
Kelly Jarvis, Marleen Vonder, Alex J Barker, Susanne Schnell, Michael Rose, James Carr, Joshua D Robinson, Michael Markl, Cynthia K Rigsby
BACKGROUND: Peak velocity measurements are used to evaluate the significance of stenosis in patients with transposition of the great arteries after the arterial switch operation (TGA after ASO). 4D flow cardiovascular magnetic resonance (CMR) provides 3-directional velocity encoding and full volumetric coverage of the great arteries and may thus improve the hemodynamic evaluation in these patients. The aim of this study was to compare peak velocities measured by 4D flow CMR with 2D phase contrast (PC) CMR and the gold standard Doppler echocardiography (echo) in patients with TGA after ASO...
September 22, 2016: Journal of Cardiovascular Magnetic Resonance
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