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Child mood disorders

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https://www.readbyqxmd.com/read/29625429/a-latent-variable-approach-to-differentiating-neural-mechanisms-of-irritability-and-anxiety-in-youth
#1
Katharina Kircanski, Lauren K White, Wan-Ling Tseng, Jillian Lee Wiggins, Heather R Frank, Stefanie Sequeira, Susan Zhang, Rany Abend, Kenneth E Towbin, Argyris Stringaris, Daniel S Pine, Ellen Leibenluft, Melissa A Brotman
Importance: Comorbidity is ubiquitous in psychiatry, but it is unclear how to differentiate neural mechanisms of co-occurring symptoms. Pediatric irritability and anxiety symptoms are prevalent and frequently co-occur. Threat orienting is pertinent to both phenotypes and is an ideal context in which to examine their unique and common neural mechanisms. Objectives: To decompose the unique and shared variances of pediatric irritability and anxiety symptoms and to determine neural correlates of these differentiated phenotypes during threat orienting...
April 6, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29617531/consanguineous-marriage-and-the-psychopathology-of-progeny-a-population-wide-data-linkage-study
#2
Aideen Maguire, Foteini Tseliou, Dermot O'Reilly
Importance: Approximately 1 in 10 children worldwide are born to consanguineous parents. The literature on consanguinity and mental health of progeny is scarce despite the fact that many of the factors associated with consanguineous unions are also associated with mental health. Objective: To investigate if children of consanguineous parents are at increased risk of common mood disorders or psychoses. Design, Setting, and Participants: This investigation was a retrospective population-wide cohort study of all individuals born in Northern Ireland between January 1, 1971, and December 31, 1986, derived from the Child Health System data set and linked to nationwide administrative data sources on prescription medication and death records...
April 4, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29607791/attention-deficit-hyperactivity-disorder-and-risk-for-psychiatric-and-neurodevelopmental-disorders-in-siblings
#3
Elina Jokiranta-Olkoniemi, Keely Cheslack-Postava, Petteri Joelsson, Auli Suominen, Alan S Brown, Andre Sourander
BACKGROUND: Probands with attention-deficit/hyperactivity disorder (ADHD) are at increased risk for several psychiatric and neurodevelopmental disorders. The risk of these disorders among the siblings of probands has not been thoroughly assessed in a population-based cohort. METHODS: Every child born in Finland in 1991-2005 and diagnosed with ADHD in 1995-2011 were identified from national registers. Each case was matched with four controls on sex, place, and date of birth...
April 2, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29554616/inflammatory-markers-as-predictors-of-depression-and-anxiety-in-adolescents-statistical-model-building-with-component-wise-gradient-boosting
#4
Consuelo Walss-Bass, Robert Suchting, Rene L Olvera, Douglas E Williamson
BACKGROUND: Immune system abnormalities have been repeatedly observed in several psychiatric disorders, including severe depression and anxiety. However, whether specific immune mediators play an early role in the etiopathogenesis of these disorders remains unknown. METHODS: In a longitudinal design, component-wise gradient boosting was used to build models of depression, assessed by the Mood-Feelings Questionnaire-Child (MFQC), and anxiety, assessed by the Screen for Child Anxiety Related Emotional Disorders (SCARED) in 254 adolescents from a large set of candidate predictors, including sex, race, 39 inflammatory proteins, and the interactions between those proteins and time...
March 12, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29540338/evaluation-of-technology-based-peer-support-intervention-program-for-preventing-postnatal-depression-protocol-for-a-randomized-controlled-trial
#5
Shefaly Shorey, Cornelia Chee, Yap-Seng Chong, Esperanza Debby Ng, Ying Lau, Cindy-Lee Dennis
BACKGROUND: Multiple international agencies, including the World Health Organization and the International Monetary Fund, have emphasized the importance of maternal mental health for optimal child health and development. Adequate social support is vital for the most vulnerable to postpartum mood disorders. Hence, an urgent need for sustainable social support programs to aid mothers ease into their new parenting role exists. OBJECTIVE: This study protocol aims to examine the effectiveness of a technology-based peer support intervention program among mothers at risk for postnatal depression in the early postpartum period...
March 14, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29540121/psychotropic-polypharmacy-among-youths-with-serious-emotional-and-behavioral-disorders-receiving-coordinated-care-services
#6
Benjamin Wu, Eric J Bruns, Ming-Hui Tai, Bethany R Lee, Ramesh Raghavan, Susan dosReis
OBJECTIVE: The study examined differences in psychotropic polypharmacy among youths with serious emotional and behavioral disorders who received coordinated care services (CCS) that used a wraparound model and a matched sample of youths who received traditional services. METHODS: A quasi-experimental design compared psychotropic polypharmacy one year before and one year after discharge from CCS. The cohort was youths with serious emotional and behavioral disorders who were enrolled in CCS from December 2009 through May 2014...
March 15, 2018: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29529472/construct-validity-and-parent-child-agreement-of-the-six-new-or-modified-disorders-included-in-the-spanish-version-of-the-kiddie-schedule-for-affective-disorders-and-schizophrenia-present-and-lifetime-version-dsm-5-k-sads-pl-5
#7
Francisco R de la Peña, Marcos F Rosetti, Andrés Rodríguez-Delgado, Lino R Villavicencio, Juan D Palacio, Cecilia Montiel, Pablo A Mayer, Fernando J Félix, Marcela Larraguibel, Laura Viola, Silvia Ortiz, Sofía Fernández, Aurora Jaímes, Miriam Feria, Liz Sosa, Lino Palacios-Cruz, Rosa E Ulloa
Changes to the Diagnostic and Statistical Manual of Mental Disorders fifth edition (DSM-5) incorporate the inclusion or modification of six disorders: Autism Spectrum Disorder, Social Anxiety Disorder, Intermittent Explosive Disorder, Disruptive Mood Dysregulation Disorder, Avoidant/Restrictive Food Intake Disorder and Binge Eating Disorder. The objectives of this study were to assess the construct validity and parent-child agreement of these six disorders in the Spanish language Schedule for Affective Disorders and Schizophrenia for School Age Children Present and Lifetime Version (K-SADS-PL-5) in a clinical population of children and adolescents from Latin America...
March 1, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29526133/satisfaction-and-psychological-after-effects-of-legal-abortion-at-a-tertiary-care-teaching-hospital-of-north-india
#8
Richa Sharma, Gita Radhakrishnan, M S Bhatia, Rashmi Gupta, Anita Mehdiratta
Psychological assessment using the Beck Depression Inventory II (BDI) on 196 eligible Medical Termination of Pregnancy (MTP) seekers showed that the depression rate prior to MTP was 12 (6.1%) and had increased to 21 (10.7%) 1 month after MTP. Risk factors included primipara, second-trimester abortion, MTP on humanitarian grounds (rape), foetal congenital anomalies and maternal illness. Psychological morbidity due to abortion greatly interferes with the interpersonal, spousal and mother-child relationships. This demands the need of counselling centres so that each MTP seeker could be counselled prior to and after MTP...
March 12, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29525040/a-mitochondrial-health-index-sensitive-to-mood-and-caregiving-stress
#9
Martin Picard, Aric A Prather, Eli Puterman, Alexanne Cuillerier, Michael Coccia, Kirstin Aschbacher, Yan Burelle, Elissa S Epel
BACKGROUND: Chronic life stress, such as the stress of caregiving, can promote pathophysiology, but the underlying cellular mechanisms are not well understood. Chronic stress may induce recalibrations in mitochondria leading to changes either in mitochondrial content per cell, or in mitochondrial functional capacity (i.e., quality). METHODS: Here we present a functional index of mitochondrial health (MHI) for human leukocytes that can distinguish between these two possibilities...
February 3, 2018: Biological Psychiatry
https://www.readbyqxmd.com/read/29520539/temperament-in-child-and-adolescent-offspring-of-patients-with-schizophrenia-and-bipolar-disorder
#10
Covadonga M Díaz-Caneja, Mª Goretti Morón-Nozaleda, Raquel P Vicente-Moreno, Elisa Rodríguez-Toscano, Laura Pina-Camacho, Elena de la Serna, Gisela Sugranyes, Inmaculada Baeza, Soledad Romero, Vanessa Sánchez-Gistau, Josefina Castro-Fornieles, Carmen Moreno, Dolores Moreno
Shared vulnerability in offspring of individuals with schizophrenia (SzO) and bipolar disorder (BpO) might manifest early during development through common temperament traits. Temperament dimensions in child and adolescent BpO (N = 80), SzO (N = 34) and the offspring of community controls (CcO) (N = 101) were assessed using the Revised Dimensions of Temperament Survey. The association between temperament dimensions and lifetime psychopathology (including threshold and subthreshold DSM-IV-TR diagnoses) and current socio-academic adjustment was assessed using logistic regression...
March 8, 2018: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29451300/decreased-anterior-cingulate-activation-in-a-motor-task-in-youths-with-bipolar-disorder
#11
Jace B King, Jeffrey S Anderson, Deborah A Yurgelun-Todd, Punitha Subramaniam, Marie R Ehrler, Melissa P Lopez-Larson
BACKGROUND: Bipolar disorder (BP) is characterized by abnormal shifts in mood between episodes of mania and severe depression, both of which have been linked with psychomotor disturbances. This study compares brain activation patterns in motor networks between euthymic youths with BP and healthy controls (HC) during the completion of a simple motor task. METHODS: Thirty-five youths with BP and 35 HC (aged 10-19) completed a self-paced sequential bilateral finger-tapping task, consisting of a 4-minute scan block with alternating 20-second periods of either the tapping task (six blocks) or rest (six blocks), while undergoing functional magnetic resonance imaging...
February 16, 2018: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29446217/clinical-staging-model-in-offspring-of-parents-with-bipolar-disorder-a-systematic-review
#12
REVIEW
Aigli Raouna, Cemre Su Osam, Angus MacBeth
OBJECTIVE: We sought to systematically review the literature on the psychiatric risk of offspring of parents with bipolar disorder (OPBD) using a developmental psychopathology framework. The review also sought to establish the utility of clinical stage modelling as a framework for identifying precursor disorders to later onset of bipolar disorder (BD) in OPBD. METHODS: A systematic search was performed using EMBASE, PsychINFO and Medline. Reference lists of included studies and previous reviews were also searched...
February 15, 2018: Bipolar Disorders
https://www.readbyqxmd.com/read/29439944/digital-peer-support-platform-7cups-as-an-adjunct-treatment-for-women-with-postpartum-depression-feasibility-acceptability-and-preliminary-efficacy-study
#13
Amit Baumel, Amanda Tinkelman, Nandita Mathur, John M Kane
BACKGROUND: Peer support is considered to be an important framework of support for mothers experiencing postpartum depression (PPD); however, some barriers exist that may limit its use including peer availability and mothers' lack of time due to child care. OBJECTIVE: This non-randomized study was designed to examine the feasibility, acceptance, and preliminary clinical outcomes of using 7 Cups of Tea (7Cups), a digital platform that delivers self-help tools and 24/7 emotional support delivered by trained volunteers, as an adjunct treatment for mothers diagnosed with PPD...
February 13, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29416845/ehmt1-mosaicism-in-apparently-unaffected-parents-is-associated-with-autism-spectrum-disorder-and-neurocognitive-dysfunction
#14
Anneke de Boer, Karlijn Vermeulen, Jos I M Egger, Joost G E Janzing, Nicole de Leeuw, Hermine E Veenstra-Knol, Nicolette S den Hollander, Hans van Bokhoven, Wouter Staal, Tjitske Kleefstra
Background: Genetic mosaicism is only detected occasionally when there are no obvious health or developmental issues. Most cases concern healthy parents in whom mosaicism is identified upon targeted testing of a genetic defect that was initially detected in their children. A germline genetic defect affecting the euchromatin histone methyltransferase 1 (EHMT1) gene causes Kleefstra syndrome, which is associated with the typical triad of distinct facial appearance, (childhood) hypotonia, and intellectual disability...
2018: Molecular Autism
https://www.readbyqxmd.com/read/29412451/prevalence-and-factors-associated-with-postpartum-depression-in-women-from-single-child-families
#15
Ribo Xiong, Aiwen Deng, Bo Wan, Yan Liu
OBJECTIVE: To investigate the prevalence of postpartum depression (PPD) and its associated factors among women without siblings from south China. METHODS: A cross-sectional study was conducted involving 468 mothers from single-child families who were assessed at 6 weeks after childbirth at a tertiary hospital in Guangzhou, China, from June 2015 to July 2016. The Chinese version of the Edinburgh Postnatal Depression Scale and a self-designed questionnaire regarding risk factors were administered to all participants...
February 7, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29397445/population-attributable-risk-of-factors-associated-with-the-repetition-of-self-harm-behaviour-in-young-people-presenting-to-clinical-services-a-systematic-review-and-meta-analysis
#16
REVIEW
Katrina Witt, Allison Milner, Matthew J Spittal, Sarah Hetrick, Jo Robinson, Jane Pirkis, Gregory Carter
The repetition of hospital-treated self-harm by young people is common. However, little work has summarised the modifiable factors associated with this. A thorough understanding of those factors most strongly associated with repetition could guide the development of relevant clinical interventions. We systematically reviewed four databases (EMBASE, Medline, PubMed and PsycINFO) until 15 April 2016 to identify all observational studies of factors for the repetition of self-harm or suicide reattempts (together referred to as 'self-harm behaviour') in young people...
February 3, 2018: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29389150/family-communication-with-teens-at-clinical-high-risk-for-psychosis-or-bipolar-disorder
#17
Julia M Salinger, Mary P O'Brien, David J Miklowitz, Sarah E Marvin, Tyrone D Cannon
Previous research has found that family problem-solving interactions are more constructive and less contentious when there is a family member with bipolar disorder compared with schizophrenia. The present study extended this research by examining whether family problem-solving interactions differ between clinical high-risk (CHR) stages of each illness. Trained coders applied a behavioral coding system (O'Brien et al., 2014) to problem-solving interactions of parents and their adolescent child, conducted just prior to beginning a randomized trial of family-focused therapy...
February 1, 2018: Journal of Family Psychology: JFP
https://www.readbyqxmd.com/read/29363588/association-between-parent-mental-health-and-paediatric-tbi-epidemiological-observations-from-the-1987-finnish-birth-cohort
#18
Michael Lowery Wilson, Olli Tenovuo, Mika Gissler, Simo Saarijärvi
BACKGROUND: This study examined whether parental mental illness has implications for child risk for traumatic brain injuries (TBI). METHOD: Data on 60 069 Finnish children born in 1987 and their parents were examined for demographic and mental health-related variables in relationship with paediatric TBI. Altogether, 15 variables were derived from the cohort data with ICD-10 F-codes being available for mental health diagnoses for all parents. Bivariate and multivariate analyses were carried out using inpatient and outpatient diagnoses of child TBI...
January 23, 2018: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/29351895/a-tailored-web-based-intervention-to-improve-parenting-risk-and-protective-factors-for-adolescent-depression-and-anxiety-problems-postintervention-findings-from-a-randomized-controlled-trial
#19
Marie Bee Hui Yap, Shireen Mahtani, Ronald M Rapee, Claire Nicolas, Katherine A Lawrence, Andrew Mackinnon, Anthony F Jorm
BACKGROUND: Depression and anxiety disorders in young people are a global health concern. Parents have an important role in reducing the risk of these disorders, but cost-effective, evidence-based interventions for parents that can be widely disseminated are lacking. OBJECTIVE: This study aimed to examine the postintervention effects of the Partners in Parenting (PiP) program on parenting risk and protective factors for adolescent depression and anxiety, and on adolescent depression and anxiety symptoms...
January 19, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29350128/between-a-rock-a-bye-and-a-hard-place-mood-disorders-during-the-peripartum-period
#20
Michael Thomson, Verinder Sharma
Mood disorders including major depressive disorder and bipolar disorder are common during and after pregnancy. Timely identification and appropriate management of mood episodes is essential to maximize maternal well-being and minimize adverse outcomes. Failure to do so results in maternal suffering and impaired child bonding, and has the potential for devastating outcomes including suicide and infanticide. Women are routinely screened for unipolar depression during or after pregnancy but not for bipolar disorder, in spite of the fact that childbirth is associated with a major risk for onset or exacerbation of bipolar disorder...
December 2017: CNS Spectrums
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