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https://www.readbyqxmd.com/read/29911521/integrated-perinatal-mental-health-care-a-national-model-of-perinatal-primary-care-in-vulnerable-populations
#1
Kimberly C Lomonaco-Haycraft, Jennifer Hyer, Britney Tibbits, Jennifer Grote, Kelly Stainback-Tracy, Claire Ulrickson, Alison Lieberman, Lies van Bekkum, M Camille Hoffman
IntroductionPerinatal mood and anxiety disorders (PMADs) are the most common complication of pregnancy and have been found to have long-term implications for both mother and child. In vulnerable patient populations such as those served at Denver Health, a federally qualified health center the prevalence of PMADs is nearly double the nationally reported rate of 15-20%. Nearly 17% of women will be diagnosed with major depression at some point in their lives and those numbers are twice as high in women who live in poverty...
June 18, 2018: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/29908775/insulin-resistance-is-associated-with-depression-risk-in-polycystic-ovary-syndrome
#2
Eleni A Greenwood, Lauri A Pasch, Marcelle I Cedars, Richard S Legro, Esther Eisenberg, Heather G Huddleston
OBJECTIVE: To test the hypothesis that insulin resistance is associated with depression risk in polycystic ovary syndrome (PCOS). DESIGN: Secondary analysis of data from a multicenter randomized trial. SETTING: Multicenter university-based clinical practices. PATIENT(S): Seven hundred thirty-eight women with PCOS by modified Rotterdam criteria seeking pregnancy enrolled in a randomized clinical trial comparing clomiphene citrate versus letrozole...
June 13, 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29899371/a-heterozygous-microdeletion-of-20q13-13-encompassing-adnp-gene-in-a-child-with-helsmoortel-van-der-aa-syndrome
#3
Minh-Tuan Huynh, Elise Boudry-Labis, Alfred Massard, Caroline Thuillier, Bruno Delobel, Bénédicte Duban-Bedu, Catherine Vincent-Delorme
Helsmoortel-van der Aa (SWI/SNF autism-related or ADNP syndrome) is an autosomal dominant monogenic syndrome caused by de novo variants in the last exon of ADNP gene and no deletions have been documented to date. We report the first case of a 3 years and 10 months old boy exhibiting typical features of ADNP syndrome, including intellectual disability, autistic traits, facial dysmorphism, hyperlaxity, mood disorder, behavioral problems, and severe chronic constipation. 60K Agilent array-comparative genomic hybridization (CGH) identified a heterozygous interstitial microdeletion at 20q13...
June 13, 2018: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/29899050/physical-exercise-programme-during-pregnancy-decreases-perinatal-depression-risk-a-randomised-controlled-trial
#4
Marina Vargas-Terrones, Ruben Barakat, Belen Santacruz, Irene Fernandez-Buhigas, Michelle F Mottola
INTRODUCTION: The incidence of depression is high during the perinatal period. This mood disorder can have a significant impact on the mother, the child and the family. OBJECTIVE: To examine the effect of an exercise programme during pregnancy on the risk of perinatal depression. METHODS: Healthy women who were <16 weeks pregnant were randomly assigned to two different groups. Women in the intervention group participated in a 60 min exercise programme throughout pregnancy, 3 days per week, which was conducted from October 2014 to December 2016...
June 13, 2018: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29892702/depressed-female-smokers-have-higher-levels-of-soluble-tumor-necrosis-factor-receptor-1
#5
Mauro Porcu, Regina Célia Bueno Rezende Machado, Mariana Urbano, Waldiceu A Verri, Ana Carolina Rossaneis, Heber Odebrecht Vargas, Sandra Odebrecht Vargas Nunes
Aim: To examine clinical and biomarkers in depressed female smokers, in order to better clarify the process that link mood disorders, childhood trauma and smoking in women. Methods: The clinical sample comprised women with unipolar or bipolar depression, divided into subgroups of smokers and never-smoker. The control groups comprised two subgroups non-depressed women, separated into smokers and never-smokers. A structured questionnaire was used to assess socio-demographic and clinical data...
June 2018: Addictive Behaviors Reports
https://www.readbyqxmd.com/read/29872304/mothers-and-fathers-of-children-with-epilepsy-gender-differences-in-post-traumatic-stress-symptoms-and-correlations-with-mood-spectrum-symptoms
#6
Claudia Carmassi, Martina Corsi, Carlo Antonio Bertelloni, Barbara Carpita, Camilla Gesi, Virginia Pedrinelli, Gabriele Massimetti, Diego Giampietro Peroni, Alice Bonuccelli, Alessandro Orsini, Liliana Dell'Osso
Background: Post-traumatic stress disorder (PTSD) and post-traumatic stress spectrum have been recently applied to understand the impact of life-threatening disease or injury in one's child; nevertheless, scant data are available on a particular chronic illness such as epilepsy whose phenotypic expression is seizures, which are acute, sudden, and unpredictable manifestations. Subjects with bipolar disorders or with mood spectrum symptoms demonstrated to be more vulnerable to develop PTSD in the aftermath of a trauma...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29870650/effect-of-maternal-migraine-on-children-s-quality-of-sleep
#7
Belma Güngen, Ahmet Yildirim, Yeşim Guzey Aras, Bilgehan Atılgan Acar, Aysel Tekeşin, Ayse Burcu Ayaz
Background and purpose: Sleep disorders are common problems associated with migraine. These sleep disorders are known to have a debilitating impact on daily lives of migraine patients. The purpose of this study is to assess the effects of sleep disorders experienced by individuals suffering from migraine on their children as well as the presence of sleep disorders in their children. Methods: This study included 96 mothers diagnosed with migraine and their 96 healthy children, and a control group formed of 74 healthy mothers and their children...
November 30, 2017: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29858853/perinatal-ssri-medications-and-offspring-hippocampal-plasticity-interaction-with-maternal-stress-and-sex
#8
REVIEW
Jodi L Pawluski, Mary Gemmel
There is growing use of selective serotonin reuptake inhibitor antidepressant (SSRI) medications during the perinatal period to treat maternal affective disorders. Perinatal SSRI exposure can have a long-term impact on offspring neuroplasticity and behavioral development that remains to be fully elucidated. This mini-review will summarize what is known about the effects of perinatal SSRIs on plasticity in the developing hippocampus, taking into account the role that maternal stress and depression may have. Emerging clinical findings and research in animal models will be discussed...
March 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29858714/parent-child-interaction-synchrony-for-infants-at-risk-for-autism-spectrum-disorder
#9
Amanda Mossman Steiner, Grace W Gengoux, Amanda Smith, Katarzyna Chawarska
This study investigated interactions between parents and 12-month-old infants at high (HR-SIBS; n = 27) and low (LR-SIBS; n = 14) familial risk for autism spectrum disorder (ASD). The contributions of parental variables, as well as child's autism symptom severity and verbal skills, to the parent interaction style were examined. Parents of HR-SIBS exhibited a higher level of synchronous-demanding behaviors, which was associated with parental report of atypical mood in the infant, but not with autism symptom severity, verbal skills, or parental depressive symptoms...
June 1, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29807325/emerging-literature-in-the-microbiota-brain-axis-and-perinatal-mood-and-anxiety-disorders
#10
REVIEW
Hannah S Rackers, Stephanie Thomas, Kelsey Williamson, Rachael Posey, Mary C Kimmel
Perinatal Mood and Anxiety Disorders (PMAD) are common and can cause significant morbidity and mortality for mother and child. A healthy perinatal period requires significant adaptations; however, systems can become imbalanced resulting in depressive and anxiety symptoms. The interface between the microbiome, the immune system, and the stress system may be a model for understanding mechanisms underlying PMAD. Emerging literature from general populations regarding immune, hormone, and HPA axis changes in relation to the microbiome combined with literature on immune, gonadotropin, and stress systems in the perinatal period provides a background...
May 17, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29802091/examining-the-impact-of-trauma-informed-cognitive-behavioral-therapy-on-perinatal-mental-health-outcomes-among-survivors-of-intimate-partner-violence-the-path-study-protocol-for-a-feasibility-study
#11
Kimberley T Jackson, Sarah Parkinson, Brianna Jackson, Tara Mantler
BACKGROUND: Intimate partner violence (IPV) is a pervasive public health problem, impacting the health and quality of life of survivors worldwide. The trauma of IPV is associated with a high incidence of mental illness, namely depressive and anxiety disorders, and posttraumatic stress disorder (PTSD). Moreover, literature endorses cognitive behavioral therapy (CBT) interventions as a gold standard for those with symptomatology consistent with anxiety disorders, mood disorders, and PTSD...
May 25, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29771555/the-quality-of-assessments-for-childhood-psychopathology-within-a-regional-medical-center
#12
Adam F Sattler, Jarrod M Leffler, Nicole L Harrison, Ewa D Bieber, Joseph J Kosmach, Leslie A Sim, Stephen P H Whiteside
Accurate assessment is essential to implementing effective mental health treatment; however, little research has explored child clinicians' assessment practices in applied settings. The current study thus examines practitioners' use of evidence-based assessment (EBA) instruments (i.e., self-report measures and structured interviews), specificity of identified diagnoses (i.e., use of specific diagnostic labels vs. nonstandardized labels, not otherwise specified [NOS] diagnoses, and adjustment disorder diagnoses), and documentation of Diagnostic and Statistical Manual of Mental Disorders (4th ed...
May 17, 2018: Psychological Services
https://www.readbyqxmd.com/read/29756987/can-pediatricians-recognize-eating-disorders-a-case-study-of-early-onset-anorexia-nervosa-in-a-male-child
#13
Emel Ataş Berksoy, Gonca Özyurt, Murat Anıl, Özlem Üzüm, Yeliz Çağan Appak
INTRODUCTION: this article examines a boy who was diagnosed with anorexia nervosa at eight years old. Pediatricians and family physicians encountered difficulties during the diagnosis and treatment stages due to the fact that early onset of the disease is rare. CASE REPORT: a boy aged eight years and four months presented with bradicardia, malnutrition and dehydration as far away from the preliminary diagnosis of anorexia nervosa investigated for possible organic pathologies at the pediatric ward...
February 27, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29708762/improvements-in-irritability-with-open-label-methylphenidate-treatment-in-youth-with-comorbid-attention-deficit-hyperactivity-disorder-and-disruptive-mood-dysregulation-disorder
#14
Drew E Winters, Sadaaki Fukui, Ellen Leibenluft, Leslie A Hulvershorn
OBJECTIVE: The purpose of this open-label study was to examine the effects of long-acting methylphenidate (MPH) treatment on irritability and related emotional symptoms associated with disruptive mood dysregulation disorder (DMDD) in youth with comorbid attention-deficit/hyperactivity disorder (ADHD). METHODS: The sample included 22 medication-free male and female subjects (ages 9-15) who met criteria for both DMDD and ADHD. Participants underwent a 4-week trial of long-acting MPH treatment (Concerta® ), with weekly dosing increases until a therapeutic dose was reached...
June 2018: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29694369/wearable-sensors-detect-childhood-internalizing-disorders-during-mood-induction-task
#15
Ellen W McGinnis, Ryan S McGinnis, Jessica Hruschak, Emily Bilek, Ka Ip, Diana Morlen, Jamie Lawler, Nestor L Lopez-Duran, Kate Fitzgerald, Katherine L Rosenblum, Maria Muzik
There is a significant need to develop objective measures for identifying children under the age of 8 who have anxiety and depression. If left untreated, early internalizing symptoms can lead to adolescent and adult internalizing disorders as well as comorbidity which can yield significant health problems later in life including increased risk for suicide. To this end, we propose the use of an instrumented fear induction task for identifying children with internalizing disorders, and demonstrate its efficacy in a sample of 63 children between the ages of 3 and 7...
2018: PloS One
https://www.readbyqxmd.com/read/29685768/accelerated-long-term-forgetting-and-behavioural-difficulties-in-children-with-epilepsy
#16
Michael B Gascoigne, Mary Lou Smith, Belinda Barton, Richard Webster, Deepak Gill, Suncica Lah
Patients with epilepsy have been shown to exhibit a range of memory deficits, including the rapid forgetting of newly-learned material over long, but not short, delays (termed accelerated long-term forgetting; ALF). Behavioural problems, such as mood disorders and social difficulties, are also overrepresented among children with epilepsy, when compared to patients with other chronic diseases and the general population. We investigated whether ALF was associated with behavioural or psychosocial deficits in children with epilepsy...
March 30, 2018: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29674252/predicting-enrollment-in-two-randomized-controlled-trials-of-nonpharmacologic-interventions-for-youth-with-primary-mood-disorders
#17
Andrea S Young, Adina M Seidenfeld, K Zachary Healy, L Eugene Arnold, Mary A Fristad
BACKGROUND: As recruitment and retention are often challenging in randomized controlled trials (RCTs), this study sought to identify predictors of participation (i.e., trial enrollment). METHOD: These analyses identified predictors of enrollment among 119 youth, ages 7-14, with a primary mood disorder, who screened eligible for the Omega-3 and Therapy pilot studies; 95 (79.8%) actually participated in the treatment. RESULTS: Youth who received some form of travel assistance (16...
August 1, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29625429/a-latent-variable-approach-to-differentiating-neural-mechanisms-of-irritability-and-anxiety-in-youth
#18
Katharina Kircanski, Lauren K White, Wan-Ling Tseng, Jillian Lee Wiggins, Heather R Frank, Stefanie Sequeira, Susan Zhang, Rany Abend, Kenneth E Towbin, Argyris Stringaris, Daniel S Pine, Ellen Leibenluft, Melissa A Brotman
Importance: Comorbidity is ubiquitous in psychiatry, but it is unclear how to differentiate neural mechanisms of co-occurring symptoms. Pediatric irritability and anxiety symptoms are prevalent and frequently co-occur. Threat orienting is pertinent to both phenotypes and is an ideal context in which to examine their unique and common neural mechanisms. Objectives: To decompose the unique and shared variances of pediatric irritability and anxiety symptoms and to determine neural correlates of these differentiated phenotypes during threat orienting...
April 6, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29617531/consanguineous-marriage-and-the-psychopathology-of-progeny-a-population-wide-data-linkage-study
#19
Aideen Maguire, Foteini Tseliou, Dermot O'Reilly
Importance: Approximately 1 in 10 children worldwide are born to consanguineous parents. The literature on consanguinity and mental health of progeny is scarce despite the fact that many of the factors associated with consanguineous unions are also associated with mental health. Objective: To investigate if children of consanguineous parents are at increased risk of common mood disorders or psychoses. Design, Setting, and Participants: This investigation was a retrospective population-wide cohort study of all individuals born in Northern Ireland between January 1, 1971, and December 31, 1986, derived from the Child Health System data set and linked to nationwide administrative data sources on prescription medication and death records...
May 1, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29607791/attention-deficit-hyperactivity-disorder-and-risk-for-psychiatric-and-neurodevelopmental-disorders-in-siblings
#20
Elina Jokiranta-Olkoniemi, Keely Cheslack-Postava, Petteri Joelsson, Auli Suominen, Alan S Brown, Andre Sourander
BACKGROUND: Probands with attention-deficit/hyperactivity disorder (ADHD) are at increased risk for several psychiatric and neurodevelopmental disorders. The risk of these disorders among the siblings of probands has not been thoroughly assessed in a population-based cohort. METHODS: Every child born in Finland in 1991-2005 and diagnosed with ADHD in 1995-2011 were identified from national registers. Each case was matched with four controls on sex, place, and date of birth...
April 2, 2018: Psychological Medicine
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