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Cochlear implants, hearing loss

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https://www.readbyqxmd.com/read/29451107/bilaterally-combined-electric-and-acoustic-hearing-in-mandarin-speaking-listeners-the-population-with-poor-residual-hearing
#1
Duo-Duo Tao, Ji-Sheng Liu, Zhen-Dong Yang, Blake S Wilson, Ning Zhou
The hearing loss criterion for cochlear implant candidacy in mainland China is extremely stringent (bilateral severe to profound hearing loss), resulting in few patients with substantial residual hearing in the nonimplanted ear. The main objective of the current study was to examine the benefit of bimodal hearing in typical Mandarin-speaking implant users who have poorer residual hearing in the nonimplanted ear relative to those used in the English-speaking studies. Seventeen Mandarin-speaking bimodal users with pure-tone averages of ∼80 dB HL participated in the study...
January 2018: Trends in Hearing
https://www.readbyqxmd.com/read/29447894/cochlear-implantation-in-pediatric-patients-with-cockayne-syndrome
#2
Renae D Van Wyhe, Claudia V Emery, Robert A Williamson
Cockayne Syndrome (CS) is a rare, autosomal recessive disorder characterized by a spectrum of phenotypic abnormalities, including progressive sensorineural hearing loss (SNHL) that involves both peripheral and central components. To date, a single series of CS patients undergoing cochlear implant (CI) placement has been reported; this study reports on additional previously unreported pediatric CI recipients. Subjective benefits were noted early after activation in both patients, and speech perception scores improved over time as well, varying from 42 to 70% (versus 0-12% previously)...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447820/how-does-a-bilingual-environment-affect-the-results-in-children-with-cochlear-implants-compared-to-monolingual-matched-children-an-italian-follow-up-study
#3
Francesca Forli, Giada Giuntini, Annalisa Ciabotti, Luca Bruschini, Ulrika Löfkvist, Stefano Berrettini
OBJECTIVES: To compare the results after cochlear implantation achieved by monolingual and bilingual deaf children implanted at our Institution, with the aim of understanding if there are any differences between the two groups and if there is a correlation between the outcomes and some patients' variables. METHODS: The study group was composed by 14 bilingual deaf children and the control group by the same number of monolingual children implanted at our Institution...
February 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447794/plasticity-after-pediatric-cochlear-implantation-implication-from-changes-in-peripheral-plasma-level-of-bdnf-and-auditory-nerve-responses
#4
Razieh Alemi, Masoud Motassadi Zarandy, Mohammad Taghi Joghataei, Ali Eftekharian, Mohammad Reza Zarrindast, Nasim Vousooghi
INTRODUCTION: Sensory neural hearing loss could lead to some structural and physiological changes in the auditory pathways, such as alteration in the expression of neurotrophins. These factors, especially Brain-Derived Neurotrophic Factor (BDNF), play an important role in synaptic functions and experience-related plasticity. Restoring cochlear function after hearing loss is possible through cochlear implantation (CI). Evaluation of the blood concentration changes of neurotrophins as prerequisites of plasticity could help scientists to determine the prognosis of CI as in the candidacy procedure or enhancing prosthesis function by adding the exact needed amount of BDNF to the electrode array...
February 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29445111/fluvastatin-protects-cochleae-from-damage-by-high-level-noise
#5
Claus-Peter Richter, Hunter Young, Sonja V Richter, Virginia Smith-Bronstein, Stuart R Stock, Xianghui Xiao, Carmen Soriano, Donna S Whitlon
Exposure to noise and ototoxic drugs are responsible for much of the debilitating hearing loss experienced by about 350 million people worldwide. Beyond hearing aids and cochlear implants, there have been no other FDA approved drug interventions established in the clinic that would either protect or reverse the effects of hearing loss. Using Auditory Brainstem Responses (ABR) in a guinea pig model, we demonstrate that fluvastatin, an inhibitor of HMG-CoA reductase, the rate-limiting enzyme of the mevalonate pathway, protects against loss of cochlear function initiated by high intensity noise...
February 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29434534/assessment-of-cochlear-function-during-cochlear-implantation-by-extra-and-intracochlear-electrocochleography
#6
Adrian Dalbert, Flurin Pfiffner, Marco Hoesli, Kanthaiah Koka, Dorothe Veraguth, Christof Roosli, Alexander Huber
Objective: The aims of this study were: (1) To investigate the correlation between electrophysiological changes during cochlear implantation and postoperative hearing loss, and (2) to detect the time points that electrophysiological changes occur during cochlear implantation. Material and Methods: Extra- and intracochlear electrocochleography (ECoG) were used to detect electrophysiological changes during cochlear implantation. Extracochlear ECoG recordings were conducted through a needle electrode placed on the promontory; for intracochlear ECoG recordings, the most apical contact of the cochlear implant (CI) electrode itself was used as the recording electrode...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29432110/the-cochlear-implant-eeg-artifact-recorded-from-an-artificial-brain-for-complex-acoustic-stimuli
#7
Luise Wagner, Natasha Maurits, Bert Maat, Deniz Baskent, Anita E Wagner
Electroencephalographic (EEG) recordings provide objective estimates of listeners' cortical processing of sounds and of the status of their speech perception system. For profoundly deaf listeners with cochlear implants (CIs), the applications of EEG are limited because the device adds electric artifacts to the recordings. This restricts the possibilities for the neural-based metrics of speech processing by CI users, for instance to gauge cortical reorganization due to individual's hearing loss history. This paper describes the characteristics of the CI artifact as recorded with an artificial head substitute, and reports how the artifact is affected by the properties of the acoustical input signal versus the settings of the device...
February 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/29424766/social-connectedness-and-perceived-listening-effort-in-adult-cochlear-implant-users-a-grounded-theory-to-establish-content-validity-for-a-new-patient-reported-outcome-measure
#8
Sarah E Hughes, Hayley A Hutchings, Frances L Rapport, Catherine M McMahon, Isabelle Boisvert
OBJECTIVES: Individuals with hearing loss often report a need for increased effort when listening, particularly in challenging acoustic environments. Despite audiologists' recognition of the impact of listening effort on individuals' quality of life, there are currently no standardized clinical measures of listening effort, including patient-reported outcome measures (PROMs). To generate items and content for a new PROM, this qualitative study explored the perceptions, understanding, and experiences of listening effort in adults with severe-profound sensorineural hearing loss before and after cochlear implantation...
February 8, 2018: Ear and Hearing
https://www.readbyqxmd.com/read/29417275/cochlear-implantation-using-the-underwater-technique-long-term-results
#9
Konrad Johannes Stuermer, David Schwarz, Andreas Anagiotos, Ruth Lang-Roth, Karl-Bernd Hüttenbrink, Jan Christoffer Luers
INTRODUCTION: The opening of the round window and the insertion of the electrode array into the scala tympani during cochlear implant surgery can lead to a pressure shock of the delicate inner ear structures. By filling the tympanic cavity with Ringer Solution during these surgical steps (underwater technique), the hydrostatic pressure of the fluid acts as a smooth pressure stabilizer, avoiding a pressure shock of the inner ear structures. The aim of this retrospective study was to present long-term results of this new method of cochlear implantation in underwater technique...
February 7, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29397946/the-audiology-of-otosclerosis
#10
REVIEW
Ali A Danesh, Navid Shahnaz, James W Hall
Diagnostic audiologic procedures for otosclerosis are effective tools in identifying this condition. Audiometric data usually demonstrate a conductive hearing loss at the early stages of otosclerosis. Modern middle ear analysis procedures are becoming more popular in the better diagnosis of otosclerosis. In clinical practice, cochlear otosclerosis can also be observed. Audiologic rehabilitation of otosclerosis includes fitting of hearing aids and implantable hearing devices. Current hearing technology enables patients who do not pursue surgical correction to function well and significantly improve their communication and quality of life...
February 1, 2018: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/29395617/unilateral-congenital-hearing-loss-in-children-challenges-and-potentials
#11
REVIEW
Astrid van Wieringen, An Boudewyns, Anouk Sangen, Jan Wouters, Christian Desloovere
The estimated incidence of sensorineural hearing impairment (>40 dB HL) at birth is 1.86 per 1000 newborns in developed countries and 30-40% of these are unilateral. Profound sensorineural unilateral hearing impairment or single sided deafness (SSD) can be treated with a cochlear implant. However, this treatment is costly and invasive and unnecessary in the eyes of many. Very young children with SSD often do not exhibit language and cognitive delays and it is hard to imagine that neurocognitive skills will present difficulties with one good ear...
January 30, 2018: Hearing Research
https://www.readbyqxmd.com/read/29381604/cochlear-implantation-in-postmeningitic-deafness
#12
Taskin Tokat, Tolgahan Catli, Feda Bayrak, Ergul Basaran Bozkurt, Levent Olgun
PURPOSE: The aim of this study is to evaluate long-term outcomes of cochlear implantation (CI) in patients with postmeningitic deafness. METHODS: Twenty-seven patients with severe to profound hearing loss due to bacterial meningitis and received CI were the subjects of this study. Surgical findings and long-term audiological performances were evaluated. Speech perception and speech intelligibility of the implanted patients were evaluated with the categories of auditory performance-II (CAP-II) test and speech intelligibility rating (SIR) test, respectively...
January 29, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29373326/results-in-adult-cochlear-implant-recipients-with-varied-asymmetric-hearing-a-prospective-longitudinal-study-of-speech-recognition-localization-and-participant-report
#13
Jill B Firszt, Ruth M Reeder, Laura K Holden, Noël Y Dwyer, Brenda Gotter, Karen Mispagel, Lisa Potts, Sallie Vanderhoof, Tim Holden, Chris Brenner, Mike Strube, Craig Buchman, Richard Chole, Andrew Drescher, Joel Goebel, Tim Hullar, Jonathan McJunkin, Gail Neely, Lisa Cowdrey, Kristen Lewis, Heidi Frazier, Sarah Zlomke, Robert Cullen, Charles Luetje
OBJECTIVES: Asymmetric hearing with severe to profound hearing loss (SPHL) in one ear and better hearing in the other requires increased listening effort and is detrimental for understanding speech in noise and sound localization. Although a cochlear implant (CI) is the only treatment that can restore hearing to an ear with SPHL, current candidacy criteria often disallows this option for patients with asymmetric hearing. The present study aimed to evaluate longitudinal performance outcomes in a relatively large group of adults with asymmetric hearing who received a CI in the poor ear...
January 25, 2018: Ear and Hearing
https://www.readbyqxmd.com/read/29370963/comparisons-of-visual-attention-in-school-age-children-with-cochlear-implants-versus-hearing-peers-and-normative-data
#14
Michael Hoffman, Elena Tiddens, Alexandra L Quittner
OBJECTIVE: Previous research has found that preschoolers with hearing loss have worse visual attention and elevated rates of behavior problems when compared to typically hearing peers (Barker et al., 2009). However, little is known about these deficits in school-age children with cochlear implants (CIs). We evaluated visual selective attention in school-age children with CIs and hearing peers and examined the link between visual attention and behavior problems. METHOD: Data were drawn from the Childhood Development after Cochlear Implantation (CDaCI) study, the largest longitudinal, multi-site study of children with CIs...
January 9, 2018: Hearing Research
https://www.readbyqxmd.com/read/29365387/-strategy-for-minimally-invasive-cochlear-implantation-and-residual-hearing-preservation
#15
Y Y Huang, J Y Chen, M Shen, J Yang
In the past few decades, considerable development was achieved in the cochlear implantation following the emergence of innovative electrode array and advances in minimally invasive surgery. Minimally invasive technique led to a better preservation of residual low-frequency hearing. The loss of residual hearing was caused by complicated factors. According to previous studies, a slower and stable speed of electrode insertion and the use of perioperative steroids were demonstrated to have a positive impact on hearing preservation...
January 7, 2018: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29360089/bpifa1-gene-expression-in-the-human-middle-ear-mucosa
#16
Yuliyan Hadzhiev, Stanislav Yordanov, Diana Popova, Darina Kachakova
OBJECTIVE: The bactericidal/permeability-increasing, fold-containing family member A1 (BPIFA1) gene codes a secretory protein (BPIFA1), which is present in the respiratory tract mucosa, and is part of the innate immune system. This study aimed to prove that BPIFA1 gene expression exists in the human middle ear mucosa. MATERIALS AND METHODS: In total, 32 patients participated in the study between March 2016 and September 2016. Seventeen patients had chronic otitis media with cholesteatoma (COMC) and 15 had bilateral sensorineural hearing loss (BSHL)...
December 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29348376/-benign-outcome-of-cochlear-implantation-in-a-patient-with-superficial-siderosis
#17
Kei Sato, Takekazu Ohi, Taisaku Shozaki, Shin Kariya
We report the case of a 38-year-old man with gait disorder and hearing loss. The patient had developed gait disorder due to a cervical meningioma since 4 year-old disappeared for 15 years after the surgical removal of the meningioma. However, at the age of 21 year-old, the gait disorder reappeared and worsened progressively. Sensorineural hearing loss (SNHL) and epileptic seizures developed during the disease course, and he was diagnosed with superficial siderosis (SS). When he was 37 years old, he experienced sudden-onset of right-side hearing impairment and was considered a candidate for cochlear implantation (CI) at the otorhinolaryngology clinic of the nearby University Hospital...
January 2018: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/29347892/pilot-study-on-the-use-of-data-mining-to-identify-cochlear-implant-candidates
#18
Jedidiah J Grisel, Erin Schafer, Anne Lam, Terry Griffin
OBJECTIVES: The goal of this pilot study was to determine the clinical utility of data-mining software that screens for cochlear implant (CI) candidacy. METHODS: The Auditory Implant Initiative developed a software module that screens for CI candidates via integration with a software system (Noah 4) that serves as a depository for hearing test data. To identify candidates, patient audiograms from one practice were exported into the screening module. Candidates were tracked to determine if any eventually underwent implantation...
January 19, 2018: Cochlear Implants International
https://www.readbyqxmd.com/read/29342054/multicenter-us-clinical-trial-with-an-electric-acoustic-stimulation-eas-system-in-adults-final-outcomes
#19
Harold C Pillsbury, Margaret T Dillon, Craig A Buchman, Hinrich Staecker, Sandra M Prentiss, Michael J Ruckenstein, Douglas C Bigelow, Fred F Telischi, Diane M Martinez, Christina L Runge, David R Friedland, Nikolas H Blevins, Jannine B Larky, George Alexiades, David M Kaylie, Peter S Roland, Richard T Miyamoto, Douglas D Backous, Frank M Warren, Hussam K El-Kashlan, Heidi K Slager, Carisa Reyes, Allison I Racey, Oliver F Adunka
OBJECTIVE: To demonstrate the safety and effectiveness of the MED-EL Electric-Acoustic Stimulation (EAS) System, for adults with residual low-frequency hearing and severe-to-profound hearing loss in the mid to high frequencies. STUDY DESIGN: Prospective, repeated measures. SETTING: Multicenter, hospital. PATIENTS: Seventy-three subjects implanted with PULSAR or SONATA cochlear implants with FLEX electrode arrays. INTERVENTION: Subjects were fit postoperatively with an audio processor, combining electric stimulation and acoustic amplification...
March 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29342037/preservation-of-cells-of-the-organ-of-corti-and-innervating-dendritic-processes-following-cochlear-implantation-in-the-human-an-immunohistochemical-study
#20
Takefumi Kamakura, Jennifer T O'Malley, Joseph B Nadol
HYPOTHESIS: This study evaluates the degree of preservation of hair cells, supporting cells, and innervating dendritic processes after cochlear implantation in the human using immunohistochemical methods. BACKGROUND: Surgical insertion of a cochlear implant electrode induces various pathologic changes within the cochlea including insertional trauma, foreign body response, inflammation, fibrosis, and neo-osteogenesis. These changes may result in loss of residual acoustic hearing, adversely affecting the use of hybrid implants, and may result in loss of putative precursor cells, limiting the success of future regenerative protocols...
January 16, 2018: Otology & Neurotology
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