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https://www.readbyqxmd.com/read/28635357/hypertrophy-of-the-ligamentum-flavum-and-expression-of-transforming-growth-factor-beta
#1
Aierken Amudong, Aikeremujiang Muheremu, Tuerhongjiang Abudourexiti
Objective To explore the relationship between cellular apoptosis and hypertrophy of the ligamentum flavum in the lumbar region. Methods Thirty patients with lumbar spinal stenosis were evaluated. Hypertrophy of the ligamentum flavum was present in 15 patients and absent in 15. Hematoxylin-eosin staining and transforming growth factor beta (TGF-β) immunohistochemical testing were applied to compare these two groups. Results Derangement of fibrous alignment, fibrocartilage changes, and infiltration of inflammatory cells were observed in the patients with hypertrophy of the ligamentum flavum, while fibrous alignment was normal and few inflammatory cells were observed in patients without hypertrophy...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28634709/incidental-durotomy-in-decompression-for-lumbar-spinal-stenosis-incidence-risk-factors-and-effect-on-outcomes-in-the-spine-tango-registry
#2
Christian Herren, Rolf Sobottke, Anne F Mannion, Thomas Zweig, Everard Munting, Philippe Otten, Tim Pigott, Jan Siewe, Emin Aghayev
PURPOSE: The three aims of this Spine Tango registry study of patients undergoing decompression for spinal stenosis were to: report the rate of dural tear (DT) stratified by treatment centre; find factors associated with an increased likelihood of incurring a DT; and compare treatment outcomes in relation to DT (none vs. repaired vs. unrepaired DT). METHODS: Multivariate logistic regression was used to assess the association between DT and patient and treatment characteristics...
June 20, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28634513/correlation-of-lumbar-lateral-recess-stenosis-in-magnetic-resonance-imaging-and-clinical-symptoms
#3
Annina Splettstößer, M Fawad Khan, Bernd Zimmermann, Thomas J Vogl, Hanns Ackermann, Marcus Middendorp, Adel Maataoui
AIM: To assess the correlation of lateral recess stenosis (LRS) of lumbar segments L4/5 and L5/S1 and the Oswestry Disability Index (ODI). METHODS: Nine hundred and twenty-seven patients with history of low back pain were included in this uncontrolled study. On magnetic resonance images (MRI) the lateral recesses (LR) at lumbar levels L4/5 and L5/S1 were evaluated and each nerve root was classified into a 4-point grading scale (Grade 0-3) as normal, not deviated, deviated or compressed...
May 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/28634309/-investigation-of-repeatability-of-residual-urine-volume-measurement-for-lower-urinary-tract-disorder-in-patients-with-lumbar-degenerative-disorders
#4
Yasufumi Ohtake, Jyunya Hanakita, Toshiyuki Takahashi, Manabu Minami, Mizuki Watanabe, Keita Kuraishi, Hirohiko Nakamura, Manabu Ueno, Taigo Kawaoka
STUDY DESIGN: prospective study OBJECTIVE:To evaluate repeatability of residual urine(RU)volume measurement(RUM)in patients with lumbar degenerative disorders. SUMMARY OF BACKGROUND DATA: RUM by abdominal echo is a non-invasive modality to evaluate lower urinary tract disorder(LUTD), repeatability of which is not found in urological disorders. Additionally, its repeatability has not been confirmed in spinal disorders. The authors examined repeatability of RUM for evaluation of LUTD in patients with lumbar degenerative disorders...
June 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28633669/impact-of-exercise-programs-among-helicopter-pilots-with-transient-lbp
#5
Knut Andersen, Roald Baardsen, Ingvild Dalen, Jan Petter Larsen
BACKGROUND: Flight related low back pain (LBP) among helicopter pilots is frequent and may influence flight performance. Prolonged confined sitting during flights seems to weaken lumbar trunk (LT) muscles with associated secondary transient pain. Aim of the study was to investigate if structured training could improve muscular function and thus improve LBP related to flying. METHODS: 39 helicopter pilots (35 men and 4 women), who reported flying related LBP on at least 1 of 3 missions last month, were allocated to two training programs over a 3-month period...
June 20, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28633540/benign-ependymoma-with-extensive-intracranial-and-spinal-cerebrospinal-fluid-dissemination-case-report-and-literature-review
#6
Fangmei Zhu, Jurong Ding, Yumei Li, Dewang Mao, Xianglei He, Wanyuan Chen, Lin Lou, Zhongxiang Ding
Myxopapillary ependymoma (MPE) is a rare variant of ependymoma that is most commonly located in the cauda equina and filum terminale. We present a case of 23-year-old man diagnosed with MPE in the fourth ventricle and sacral canal area with extensive disseminated lesions along the cerebrospinal ventricular system. Additionally, a molecular pathological diagnosis was performed. The patient underwent a craniotomy and a lumbar laminectomy. In the course of 18 months of follow-up, the patient have recovered very well...
June 21, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/28633411/surgeon-level-variability-in-outcomes-cost-and-comorbidity-adjusted-cost-for-elective-lumbar-decompression-and-fusion
#7
Silky Chotai, Ahilan Sivaganesan, John A Sielatycki, Kristin R Archer, Richard Call, Matthew J McGirt, Clinton J Devin
BACKGROUND: The costs and outcomes following degenerative spine surgery may vary from surgeon to surgeon. Patient factors such as comorbidities may increase the health care cost. These variations are not well studied. OBJECTIVE: To understand the variation in outcomes, costs, and comorbidity-adjusted cost for surgeons performing lumbar laminectomy and fusions surgery. METHODS: A total of 752 patients undergoing laminectomy and fusion, performed by 7 surgeons, were analyzed...
June 14, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28633066/an-emg-assisted-modeling-approach-to-assess-passive-lumbar-tissue-loading-in-vivo-during-trunk-bending
#8
Xiaopeng Ning
Lower back pain (LBP) is a condition with high prevalence and high cost both in the United States and around the world. The magnitude of mechanical loading on spine is strongly associated with the occurrence of LBP. Previously, to assess spinal loading, biologically assisted biomechanical models were developed to estimate trunk muscle contraction forces. Loadings on lumbar passive tissues are estimated using anatomical models. However, despite the substantial individual variability in lumbar ligament geometry and viscoelastic properties, the existing anatomical models do not account for these differences...
June 10, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/28632693/extraosseous-extension-of-aggressive-vertebral-hemangioma-as-a-potential-pitfall-on-68ga-psma-pet-ct
#9
Stephan Probst, Franck Bladou, Gad Abikhzer
A 74-year-old man with newly diagnosed prostate cancer underwent Ga-PSMA PET/CT, which demonstrated intense uptake in and adjacent the L2 vertebral body. Subsequent MRI of the lumbar spine showed an aggressive L2 hemangioma with adjacent soft tissue extension. There was congruence of the intraosseous and extraosseous components of the hemangioma and the PSMA PET uptake. This is a rare but important potential pitfall in Ga-PSMA PET/CT-a soft tissue lesion with intense tracer uptake related not to a nodal metastasis of prostate cancer but to extraosseous extension of an aggressive vertebral body hemangioma...
June 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28632645/management-of-symptomatic-lumbar-disk-herniation-an-international-perspective
#10
Pravesh S Gadjradj, Mark P Arts, Maurits W van Tulder, Wim J R Rietdijk, Wilco C Peul, Biswadjiet S Harhangi
STUDY DESIGN: A questionnaire survey. OBJECTIVE: To evaluate the current practice patterns of surgeons regarding both the surgical and nonsurgical management of lumbar disk herniation (LDH) worldwide and to compare this with the current literature. SUMMARY OF BACKGROUND DATA: Sciatica is a common diagnosis in the general population. Sciatica is most frequently caused by LDH. Multiple surgical techniques and treatment modalities are available to treat LDH, albeit some with small effect sizes or without compelling evidence...
June 19, 2017: Spine
https://www.readbyqxmd.com/read/28632644/do-former-smokers-exhibit-a-distinct-profile-before-and-after-lumbar-spine-surgery
#11
Ehsan Jazini, Steven D Glassman, Erica F Bisson, Eric A Potts, Leah Y Carreon
STUDY DESIGN: Retrospective longitudinal cohort OBJECTIVES.: To determine if former smokers undergoing lumbar spine surgery have distinct baseline and post-operative Patient Reported Outcomes (PROs) compared to never smokers and current smokers SUMMARY OF BACKGROUND DATA.: Smoking has known deleterious effects on patients undergoing lumbar spine surgery. However, former smokers have not been extensively evaluated. There are few studies regarding the relationship between pack-years or duration of smoking cessation, and subsequent clinical outcome...
June 19, 2017: Spine
https://www.readbyqxmd.com/read/28632643/the-early-impact-of-postoperative-bracing-on-pain-and-quality-of-life-following-posterior-instrumented-fusion-for-lumbar-degenerative-conditions-a-randomized-trial
#12
Hany Ag Soliman, Soraya Barchi, Stefan Parent, Gilles Maurais, Alain Jodoin, Jean-Marc Mac-Thiong
STUDY DESIGN: A randomized controlled trial. OBJECTIVE: To investigate if bracing after posterior spinal instrumented fusion(PSIF) can improve pain relief and quality of life(QoL) 6 weeks and 3 months postoperatively. SUMMARY OF BACKGROUND DATA: Braces are commonly prescribed after PSIF in patients with lumbar degenerative conditions with the aim of improving pain relief and QoL. However, there is a lack of evidence on the indication for postoperative bracing, as surgeons use braces mainly based on their experience and training...
June 19, 2017: Spine
https://www.readbyqxmd.com/read/28632565/neuroforaminal-bone-growth-following-minimally-invasive-transforaminal-lumbar-interbody-fusion-with-bmp-a-computed-tomographic-analysis
#13
Junyoung Ahn, Anton Y Jorgensen, Daniel D Bohl, Ehsan Tabaraee, Vincent J Rossi, Khaled Aboushaala, Kern Singh
STUDY DESIGN: Computed tomographic analysis. OBJECTIVE: To identify radiographic patterns of symptomatic neuroforaminal bone growth (NFB) in patients who have undergone a single-level minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) augmented with bone morphogenetic proteins (BMP) utilizing computed tomography (CT). SUMMARY OF BACKGROUND DATA: BMP induces osteoblast differentiation leading to new bone formation. The association of BMP utilization and heterotopic bone formation after an MIS-TLIF has been described...
July 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28632564/accuracy-of-percutaneous-pedicle-screw-placement-does-training-level-matter
#14
Evan O Baird, Steven J McAnany, Samuel Overley, Branko Skovrlj, Javier Z Guzman, Sheeraz A Qureshi
STUDY DESIGN: In vitro human cadaveric surgical technique study. OBJECTIVE: To assess the accuracy of percutaneous pedicle screw placement in a human cadaveric model using standard fluoroscopic guidance technique, compared across varying levels of experience. SUMMARY OF BACKGROUND DATA: The current literature varies widely in the reported frequency of facet violation during placement of percutaneous pedicle screws. However, as of yet there are no studies examining the effect that training level has on accuracy of placement...
July 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28632563/why-lumbar-artificial-disk-replacements-ladrs-fail
#15
Kenneth Pettine, Robert Ryu, Fernando Techy
STUDY DESIGN: A retrospective review of prospectively collected data. OBJECTIVE: To determine why artificial disk replacements (ADRs) fail by examining results of 91 patients in FDA studies performed at a single investigational device exemption (IDE) site with minimum 2-year follow-up. SUMMARY OF BACKGROUND DATA: Patients following lumbar ADR generally achieve their 24-month follow-up results at 3 months postoperatively. MATERIALS AND METHODS: Every patient undergoing ADR at 1 IDE site by 2 surgeons was evaluated for clinical success...
July 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28632562/degenerative-changes-of-the-facet-joints-in-adults-with-lumbar-spondylolysis
#16
Yuichiro Goda, Toshinori Sakai, Taihei Harada, Shoichiro Takao, Yoichiro Takata, Kosaku Higashino, Masafumi Harada, Koichi Sairyo
STUDY DESIGN: Radiologic analysis using computed tomography. OBJECTIVES: To analyze the degenerative changes of the facet joints in patients with spondylolysis in comparison with control subjects. SUMMARY OF BACKGROUND DATA: Defects of the pars interarticularis are thought to result in a reduction of biomechanical stress on adjacent facet joints. Therefore, degenerative changes of the facet joints in patients with spondylolysis are expected to be less than those in patients without spondylolysis...
July 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28632561/early-postoperative-magnetic-resonance-imaging-in-detecting-radicular-pain-after-lumbar-decompression-surgery-retrospective-study-of-the-relationship-between-dural-sac-cross-sectional-area-and-postoperative-radicular-pain
#17
Toshimasa Futatsugi, Jun Takahashi, Hiroki Oba, Shota Ikegami, Yuji Mogami, Syunichi Shibata, Yoshihito Ohji, Hirotaka Tanikawa, Hiroyuki Kato
STUDY DESIGN: A retrospective analysis. OBJECTIVE: To evaluate the association between early postoperative dural sac cross-sectional area (DCSA) and radicular pain. SUMMARY OF BACKGROUND DATA: The correlation between postoperative magnetic resonance imaging (MRI) findings and postoperative neurological symptoms after lumbar decompression surgery is controversial. METHODS: This study included 115 patients who underwent lumbar decompression surgery followed by MRI within 7 days postoperatively...
July 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28632560/preoperative-depression-smoking-and-employment-status-are-significant-factors-in-patient-satisfaction-after-lumbar-spine-surgery
#18
Laura Chapin, Kelly Ward, Timothy Ryken
STUDY DESIGN: Prospective cohort study. OBJECTIVE: To determine whether comorbidities and demographics, identified preoperatively, can impact patient outcomes and satisfaction after lumbar spine surgery. SUMMARY OF BACKGROUND DATA: The surgical treatment of lower back pain does not always eliminate a patient's pain and symptoms. Revision surgeries are costly and expose the patient to additional risk. We aim to identify patient characteristics that may suggest a greater or lesser likelihood of postsurgical success by examining patient-reported measures and outcomes after surgery...
July 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28632559/counting-the-cost-of-failed-spinal-fusion-for-relief-of-low-back-pain-does-primary-fusion-with-bone-morphogenetic-protein-make-economic-sense-from-a-primary-payer-perspective
#19
Adam P Lloyd
STUDY DESIGN: A retrospective cohort study. OBJECTIVES: To investigate the unknown direct costs of failed instrumented lumbar fusion using iliac crest bone graft (ICBG) and subsequent reoperation utilizing recombinant human bone morphogenetic protein-2 (rhBMP-2) from a primary payer perspective. SUMMARY OF BACKGROUND DATA: Recent evidence has demonstrated increased rates of instrumented lumbar fusion and utilization of rhBMP-2 to treat a range of conditions causing lower back pain...
July 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28632558/the-long-term-clinical-effect-of-minimal-invasive-tlif-technique-in-1-segment-lumbar-disease
#20
Yi-Bing Li, Xiao-Dong Wang, Hong-Wei Yan, Ding-Jun Hao, Zheng-Hua Liu
STUDY DESIGN: A prospective cohort double-center study. OBJECTIVE: To assess the clinical effect of minimally invasive transforaminal lumbar interbody fusion (miTLIF) using the tunnel technique. SUMMARY OF BACKGROUND DATA: A series of short-term studies have indicated that miTLIF could reduce blood loss and improve clinical results. However, long-term clinical study and magnetic resonance imaging research are still scare. METHODS: From January 2008 to January 2009, 187 patients with 1-segment lumbar disease requiring intervertebral fusion were enrolled in this study...
July 2017: Clinical Spine Surgery
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