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https://www.readbyqxmd.com/read/28329630/body-mass-index-height-and-early-onset-basal-cell-carcinoma-in-a-case-control-study
#1
Yanchang Zhang, Brenda Cartmel, Courtney C Choy, Annette M Molinaro, David J Leffell, Allen E Bale, Susan T Mayne, Leah M Ferucci
BackgroundBasal cell carcinoma (BCC) is the most common malignancy in the US. Body mass index (BMI) and height have been associated with a variety of cancer types, yet the evidence regarding BCC is limited. Therefore, we evaluated BMI and height in relation to early- onset BCC and explored the potential role of ultraviolet (UV) radiation exposure as well as estrogen-related exposures in the BMI-BCC relationship.MethodsBCC cases (n=377) diagnosed under age 40 were identified through a central dermatopathology facility in Connecticut...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28329413/physical-activity-muscular-strength-and-polypharmacy-among-older-multimorbid-persons-results-from-the-kora-age-study
#2
K A Volaklis, B Thorand, A Peters, M Halle, M Heier, B Strasser, U Amann, K H Ladwig, H Schulz, W Koenig, C Meisinger
The purpose of this study was to examine if physical activity (PA) and muscular strength (MS) are related to polypharmacy. Our cross-sectional analysis was based on 711 patients with multimorbidity (ΜΜΒ), aged 65-94 years, who participated in the KORA-Age study. Participants underwent a face to face interview and extensive physical examinations including anthropometric measurements, registration of chronic diseases, determination of health-related behaviors (smoking, alcohol intake, physical activity, etc), collection of blood samples and measurement of hand-grip strength...
March 22, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28329172/the-obesity-paradox-is-still-there-a-risk-analysis-of-over-15-000-cardiosurgical-patients-based-on-body-mass-index
#3
Martin Hartrumpf, Ralf-Uwe Kuehnel, Johannes M Albes
OBJECTIVES: Obesity is an ever-growing problem in contemporary cardiac surgery. Although it accounts for many perioperative comorbidities, it has not been shown to increase mortality. Body mass index (BMI) is therefore not considered in the European System for Cardiac Operative Risk Evaluation (EuroSCORE). We sought to confirm whether this holds true for our own single-centre patient population. METHODS: Data from 15 314 consecutive patients receiving major cardiac surgery at our institution were analysed...
March 18, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28329091/association-between-sleep-timing-obesity-diabetes-the-hispanic-community-health-study-study-of-latinos-hchs-sol-cohort-study-sleep-timing-obesity-and-diabetes
#4
Kristen L Knutson, Donghong Wu, Sanjay R Patel, Jose S Loredo, Susan Redline, Jianwen Cai, Linda C Gallo, Yasmin Mossavar-Rahmani, Alberto R Ramos, Yanping Teng, Martha L Daviglus, Phyllis C Zee
Study Objectives: Recent studies implicate inadequate sleep duration and quality in metabolic disease. Fewer studies have examined the timing of sleep, which may be important because of its potential impact on circadian rhythms of metabolic function. We examined the association between sleep timing and metabolic risk among Hispanic/Latino adults. Methods.: Cross-sectional data from community-based study of 13,429 participants aged 18-74 years. People taking diabetes medications were excluded...
January 28, 2017: Sleep
https://www.readbyqxmd.com/read/28329090/antiretrovirals-fractures-and-osteonecrosis-in-a-large-international-hiv-cohort
#5
Álvaro H Borges, Jennifer Hoy, Eric Florence, Dalibor Sedlacek, Hans-Jürgen Stellbrink, Vilma Uzdaviniene, Janez Tomazic, Panagiotis Gargalianos-Kakolyris, Patrick Schmid, Chloe Orkin, Court Pedersen, Clifford Leen, Christian Pradier, Fiona Mulcahy, Anna Lisa Ridolfo, Therese Staub, Fernando Maltez, Rainer Weber, Leo Flamholc, Galina Kyselyova, Jens D Lungren, Amanda Mocroft
Background: Antiretrovirals (ARVs) affect bone density and turnover, but their effect on risk of fractures and osteonecrosis of the femoral head is less understood. We investigated if exposure to ARVs increases the risk of both bone outcomes. Methods: EuroSIDA participants were followed to assess fractures and osteonecrosis. Poisson regression identified clinical, laboratory and demographic predictors of either bone outcome. Ever, current and cumulative exposures to ARVs were assessed...
February 22, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28329086/obesity-history-and-daily-patterns-of-physical-activity-at-age-60-64-years-findings-from-the-mrc-national-survey-of-health-and-development
#6
Rachel Cooper, Lei Huang, Rebecca Hardy, Adina Crainiceanu, Tamara Harris, Jennifer A Schrack, Ciprian Crainiceanu, Diana Kuh
Background: The aim of this study was to investigate associations of current body mass index (BMI) and obesity history with daily patterns of physical activity. Methods: At age 60-64, participants from a British birth cohort study wore accelerometers for 5 days. Accelerometry counts were log-transformed and mean log-counts were used to derive a summary variable indicating total daily log-activity counts. Among those with complete data (n = 1,388) the associations of current BMI and age of first obesity were examined with: (a) total daily log-activity counts and (b) total log-activity counts in four segments of the day...
February 18, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28329079/sleep-duration-and-cardiometabolic-risk-among-chinese-school-aged-children-do-adipokines-play-a-mediating-role
#7
Lujiao Li, Junling Fu, Xin Ting Yu, Ge Li, Lu Xu, Jinghua Yin, Hong Cheng, Dongqing Hou, Xiaoyuan Zhao, Shan Gao, Wenhui Li, Changhong Li, Struan F A Grant, Mingyao Li, Yi Xiao, Jie Mi, Ming Li
Objective: To assess the associations between sleep duration and cardiometabolic risk factors in Chinese school-aged children and to explore the possible mediating role of adipokines. Methods: Sleep duration was collected in 3,166 children from the Beijing Child and Adolescent Metabolic Syndrome study. Glucose homeostasis and other cardiometabolic risk factors were assessed. Serum adipokines including leptin, total and high-molecular-weight (HMW) adiponectin, resistin, fibroblast growth factor 21 (FGF21) and retinol binding protein 4 (RBP4) were determined...
March 9, 2017: Sleep
https://www.readbyqxmd.com/read/28328829/combined-effect-of-obesity-and-uric-acid-on-nonalcoholic-fatty-liver-disease-and-hypertriglyceridemia
#8
Shujun Zhang, Tingting Du, Mengni Li, Huiming Lu, Xuan Lin, Xuefeng Yu
Hyperuricemia is associated with metabolic syndrome (MetS), but the association is often confounded by the shared background of obesity. We sought to explore the modifying effects of obesity on the association between uric acid (UA), MetS components, and nonalcoholic fatty liver disease (NAFLD).We conducted a cross-sectional study in a Chinese population of 10,069 participants aged ≥20 years. Multiplicative interaction between obesity (BMI ≥25 kg/m) and elevated UA was assessed using an interaction term in a logistic regression analysis...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28328798/body-mass-index-and-the-risk-of-low-bone-mass-related-fractures-in-women-compared-with-men-a-prisma-compliant-meta-analysis-of-prospective-cohort-studies
#9
Bing-Yan Xiang, Wei Huang, Guo-Qi Zhou, Ning Hu, Hong Chen, Cheng Chen
BACKGROUND: Body mass index (BMI) is inconsistently associated with the progression of low bone mass-related fractures. We conducted a systematic review and meta-analysis to summarize the evidence regarding the relationship between BMI and the risk of fracture in men and women separately. Furthermore, we analyzed the association between BMI and fracture risk in women compared with men. METHODS: PubMed, EmBase, and the Cochrane Library were searched up to November 2015 to identify prospective cohort studies of low bone mass-related fractures...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28328730/partial-occlusion-conversion-from-thoracotomy-undelayed-but-shorter-occlusion-resuscitative-endovascular-balloon-occlusion-of-the-aorta-strategy-in-japan
#10
Yosuke Matsumura, Junichi Matsumoto, Hiroshi Kondo, Koji Idoguchi, Tomohiro Funabiki
INTRODUCTION: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a viable alternative to resuscitative thoracotomy (RT) in refractory hemorrhagic patients. We evaluated REBOA strategies using Japanese multi-institutional data. PATIENTS AND METHODS: The DIRECT-IABO investigators registered trauma patients requiring REBOA from 18 hospitals. Patients' characteristics, outcomes, and time in initial treatment were collected and analyzed. RESULTS: From August 2011 to December 2015, 106 trauma patients were analyzed...
March 21, 2017: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/28328551/higher-body-mass-index-is-associated-with-greater-proportions-of-effector-cd8-t-cells-expressing-cd57-in-women-living-with-hiv
#11
Michael J A Reid, Sanjiv M Baxi, Lila A Sheira, Alan L Landay, Edward A Frongillo, Adebola Adedimeji, Mardge H Cohen, Eryka Wentz, Deborah R Gustafson, Daniel Merenstein, Peter W Hunt, Phyllis C Tien, Sheri D Weiser
BACKGROUND: A low proportion of CD28-CD8+ T cells that express CD57 is associated with increased mortality in HIV infection. The effect of increasing BMI changes in the proportion of CD57+CD28-CD8+ T cells among HIV-infected individuals on ART is unknown. SETTING: In a U.S. cohort of HIV-infected women, we evaluated associations of BMI and waist circumference with 3 distinct CD8+ T cell phenotypes: % CD28-CD57+CD8+ T cells, % CD57+ of CD28-CD8+ T cells and % CD28- of all CD8 T cells...
March 20, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28328282/frequency-of-erectile-dysfunction-in-males-with-central-serous-chorioretinopathy
#12
Ayse Balkarli, Muhammet Kazim Erol, Soner Yalcinkaya, Rumeysa Selvinaz Erol
OBJECTIVES: To evaluate the frequency of sexual dysfunction and associated factors in patients with central serous chorioretinopathy (CSCR). MATERIAL AND METHODS: Fifty-eight CSCR patients who met the inclusion criteria and 99 age- and sex-matched healthy controls were prospectively investigated for sexual dysfunction and associated factors. All participants were investigated using the Beck Depression Inventory (BDI), Beck Anxiety Scale (BAS), and the15-question Index of Erectile Function-15 (IIEF-15) and by extensive examination of CSCR, associated factors, and confounding factors...
March 22, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28327672/tox-and-adipoq-gene-polymorphisms-are-associated-with-antipsychotic-induced-weight-gain-in-han-chinese
#13
Shen Li, Chengai Xu, Yuan Tian, Xueshi Wang, Rui Jiang, Miaomiao Zhang, Lili Wang, Guifu Yang, Ying Gao, Chenyu Song, Yukun He, Ying Zhang, Jie Li, Wei-Dong Li
To find the genetic markers related to the antipsychotic-induced weight gain (AIWG), we analyzed associations among candidate gene single-nucleotide polymorphisms (SNPs) and quantitative traits of weight changes and lipid profiles in a Chinese Han population. A total of 339 schizophrenic patients, including 86 first-episode patients (FEPs), meeting the entry criteria were collected. All patients received atypical antipsychotic drug monotherapy and hospitalization and were followed for 12 weeks. Forty-three SNPs in 23 candidate genes were calculated for quantitative genetic association with AIWG, performed by PLINK...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28327649/adiposity-in-childhood-brain-tumors-a-report-from-the-canadian-study-of-determinants-of-endometabolic-health-in-children-candecide-study
#14
Kuan-Wen Wang, Russell J de Souza, Adam Fleming, Sheila K Singh, Donna L Johnston, Shayna M Zelcer, Shahrad Rod Rassekh, Sarah Burrow, Katrin Scheinemann, Lehana Thabane, M Constantine Samaan
Children with brain tumors (CBT) are at high risk of cardiovascular diseases and type 2 diabetes compared to the general population. Recently, adiposity has been reported to be more informative for cardiometabolic risk stratification than body mass index (BMI) in the general population. The goal of this study is to describe the adiposity phenotype in CBT, and to establish adiposity determinants. We recruited CBT (n = 56) and non-cancer controls (n = 106). Percent body fat (%FM), waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR) were measured to determine total and central adiposity, respectively...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28327601/bcip-a-gene-centered-platform-for-identifying-potential-regulatory-genes-in-breast-cancer
#15
Jiaqi Wu, Shuofeng Hu, Yaowen Chen, Zongcheng Li, Jian Zhang, Hanyu Yuan, Qiang Shi, Ningsheng Shao, Xiaomin Ying
Breast cancer is a disease with high heterogeneity. Many issues on tumorigenesis and progression are still elusive. It is critical to identify genes that play important roles in the progression of tumors, especially for tumors with poor prognosis such as basal-like breast cancer and tumors in very young women. To facilitate the identification of potential regulatory or driver genes, we present the Breast Cancer Integrative Platform (BCIP, http://omics.bmi.ac.cn/bcancer/). BCIP maintains multi-omics data selected with strict quality control and processed with uniform normalization methods, including gene expression profiles from 9,005 tumor and 376 normal tissue samples, copy number variation information from 3,035 tumor samples, microRNA-target interactions, co-expressed genes, KEGG pathways, and mammary tissue-specific gene functional networks...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28327563/health-benefits-and-consequences-of-the-eastern-orthodox-fasting-in-monks-of-mount-athos-a-cross-sectional-study
#16
S N Karras, A Persynaki, A Petróczi, E Barkans, H Mulrooney, M Kypraiou, T Tzotzas, K Tziomalos, K Kotsa, A A Tsioudas, C Pichard, D P Naughton
BACKGROUND/OBJECTIVES: Greek Orthodox fasting (OF), which involves 180-200 days of fasting per year, is dictated by the Christian Orthodox religion. For the first time, this cross-sectional study examines the characteristics and the effects of OF on anthropometry, cardiometabolic markers and calcium homeostasis in Athonian monks (AMs). SUBJECTS/METHODS: Daily intakes of energy, macro- and micronutrients of a day during a weekend of Nativity Fast, defined as non-restrictive day (NRD), and a weekday during Great Lent, labeled as restrictive day (RD) were recorded...
March 22, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28327294/reference-values-for-the-scalene-interval-width-during-varying-degrees-of-glenohumeral-abduction-using-ultrasonography
#17
Ross Mattox, Patrick J Battaglia, Aaron B Welk, Yumi Maeda, Daniel W Haun, Norman W Kettner
OBJECTIVE: The aim of this study was to establish reference values for the width of the interval between the anterior and middle scalene muscles using ultrasonography during varying degrees of glenohumeral joint (GH) abduction. Reliability and body mass index (BMI) data were also assessed. METHODS: Interscalene triangles of asymptomatic participants were scanned bilaterally in the transverse plane. Images were obtained at 0°, 90°, and 150° of GH abduction with the participant seated...
November 2016: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28327265/association-between-body-mass-index-and-caries-experience-in-brazilian-children-and-adolescents
#18
Raquel Assed Bezerra da Silva, Driely Barreiros, Sara Oliveira, Lea Assed Bezerra da Silva, Paulo Nelson-Filho, Erika Calvano Küchler
PURPOSE: The purpose of this study was to evaluate the association between caries and body mass index (BMI) deviations in Brazilian schoolchildren and adolescents. METHODS: A total of 237 three- to 15-year-old children, all undergoing treatment in a university pediatric dental clinic, was evaluated. Caretakers answered a questionnaire on sociodemographic, ethnicity, oral hygiene, and dietary information. The children's height was measured in centimeters, the weight in kilograms, and BMIs were calculated...
September 15, 2016: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/28327108/impact-of-the-ultrasonic-scalpel-on-the-amount-of-drained-lymph-after-axillary-or-inguinal-lymphadenectomy
#19
Olivier Gié, Marie-Laure Matthey-Gié, Pedro-Manuel Marques-Vidal, Nicolas Demartines, Maurice Matter
BACKGROUND: Seroma formation and lymphoedema are frequently encountered complications after radical lymph node dissection (RLND). Attempts to reduce the lymphatic morbidity include the use of Ultrasonic Scalpel. The aim of the present analysis was to assess the impact of the ultrasonic scalpel on the amount of drained lymph after lymph node dissection. METHODS: Patients listed for a RLND or completion lymph node dissection (CLND) were enrolled in a prospective randomized trial to compare the impact of two surgical dissection techniques (USS versus control) on the amount of drained lymph...
March 21, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28326518/chorionic-thickness-and-plgf-concentrations-as-early-predictors-of-small-for-gestational-age-birth-weight-in-a-low-risk-population
#20
Anna Gąsiorowska, Marek Pietryga, Agnieszka Zawiejska, Piotr Dydowicz, Katarzyna Ziółkowska, Hubert Wolski, Jacek Brązert
OBJECTIVES: SGA is associated with higher incidence of postnatal complications, including suboptimal neurodevelopment and increased cardiovascular risk. Screening for SGA, carried out at 11-13 (+ 6d) gestational weeks enables to reduce or completely eliminate the above mentioned complications. The aim of this study was to assess the correlation between chorionic thickness, concentration of PIGF protein and foetal birth weight in a single low-risk pregnancy. MATERIAL AND METHODS: The study included 76 patients at 11-13 (+ 6d) gestational weeks, monitored throughout preg-nancy...
2017: Ginekologia Polska
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