keyword
https://read.qxmd.com/read/38389873/carbopol-940-based-hydrogels-loading-synergistic-combination-of-quercetin-and-luteolin-from-the-herb-euphorbia-humifusa-to-promote-staphylococcus-aureus-infected-wound-healing
#1
JOURNAL ARTICLE
Xiying Wu, Hao-Wei Chen, Ze-Yu Zhao, Lisha Li, Chi Song, Juan Xiong, Guo-Xun Yang, Quangang Zhu, Jin-Feng Hu
With the increasing prevalence of Staphylococcus aureus infections, rapid emergence of drug resistance and the slow healing of infected wounds, developing an efficient antibiotic-free multifunctional wound dressing for inhibiting S. aureus and simultaneously facilitating wound healing have become a huge challenge. Due to their excellent biocompatibility and biodegradability, some carbopol hydrogels based on plant extracts or purified compounds have already been applied in wound healing treatment. In China, Euphorbia humifusa Willd...
February 21, 2024: RSC medicinal chemistry
https://read.qxmd.com/read/38301987/diterpenoid-tanshinones-inhibit-gastric-cancer-angiogenesis-through-the-pi3k-akt-mtor-signaling-pathway
#2
JOURNAL ARTICLE
Jie-Ru Yu, Yu-Yue Liu, Yang-Yang Gao, Li-Hui Qian, Jia-Lin Qiu, Pei-Pei Wang, Guang-Ji Zhang
ETHNOPHARMACOLOGICAL RELEVANCE: Salvia miltiorrhiza Bunge is a kind of Chinese herbal medicine known for activating blood circulation and removing blood stasis, with the effect of cooling blood and eliminating carbuncles, and has been proven to have the effect of treating tumors. However, the inhibitory effect of Salvia miltiorrhiza Bunge extracts (Diterpenoid tanshinones) on tumors by inhibiting angiogenesis has not been studied in detail. AIM OF THE STUDY: This study aimed to investigate the anti-gastric cancer effect of diterpenoid tanshinones (DT) on angiogenesis, including the therapeutic effects and pathways...
January 30, 2024: Journal of Ethnopharmacology
https://read.qxmd.com/read/38278374/classical-prescription-floris-sophorae-powder-treat-colorectal-cancer-by-regulating-kras-mek-erk-signaling-pathway
#3
JOURNAL ARTICLE
Li-Ying Han, Hao Yu, Shuai Wang, Yong-Rui Bao, Tian-Jiao Li, Ying Zheng, Xi Luo, Meng-Nan Jia, Qiang Zhang, Xian-Sheng Meng
ETHNOPHARMACOLOGICAL RELEVANCE: Colorectal cancer (CRC) belongs to the category of intestinal wind, anal ulcer, abdominal mass and other diseases in traditional Chinese medicine (TCM). Floris Sophorae Powder (F.S), is a classical prescription is recorded in Puji Benshi Fang for the treatment of intestinal carbuncle. It has been incorporated into the prescriptions for the treatment of intestinal diseases and achieved remarkable results in modern medicine. However, the mechanism of F.S in the treatment of colorectal cancer remains unclear and requires further study...
January 24, 2024: Journal of Ethnopharmacology
https://read.qxmd.com/read/38237513/salvia-miltiorrhiza-bunge-extract-and-przewalskin-ameliorate-bleomycin-induced-pulmonary-fibrosis-by-inhibition-of-apoptosis-oxidative-stress-and-collagen-deposition-via-the-tgf-%C3%AE-1-pathway
#4
JOURNAL ARTICLE
Mengnan Zeng, Aozi Feng, Yingjie Ren, Qinqin Zhang, Ru Wang, Beibei Zhang, Meng Liu, Pengli Guo, Yuhan Zhang, Jun Lyu, Xiaoke Zheng
BACKGROUND: Salvia miltiorrhiza Bunge (Labiatae) (DS) is a key part of the traditional Chinese medicine, whose roots are used to remove blood stasis, relieve pain, eliminate carbuncle and calm the nerves. Our research team found that the DS extract could significantly reverse LPS-induced lung injury, and five new diterpenoid quinones in DS extract with excellent lung protective activity for the first time. However, the material basis and mechanism of DS on pulmonary fibrosis (PF) needs to be explored in depth...
January 14, 2024: Phytomedicine
https://read.qxmd.com/read/38179404/anti-tumor-effect-of-coix-seed-based-on-the-theory-of-medicinal-and-food-homology
#5
REVIEW
Fan-Di Meng, Ling Yuan, Dou-Dou Lu, Ya-Ting Yang, Duo-Jie Xu, Meng-Ying Che, Yi Nan
Coix seed is a dry and mature seed of Coix lacryma-jobi L.var.ma-yuen (Roman.) Stapf in the Gramineae family. Coix seed has a sweet, light taste, and a cool nature. Coix seed enters the spleen, stomach, and lung meridians. It has the effects of promoting diuresis and dampness, strengthening the spleen to prevent diarrhea, removing arthralgia, expelling pus, and detoxifying and dispersing nodules. It is used for the treatment of edema, athlete's foot, poor urination, spleen deficiency and diarrhea, dampness and obstruction, lung carbuncle, intestinal carbuncle, verruca, and cancer...
December 24, 2023: World Journal of Clinical Oncology
https://read.qxmd.com/read/38175656/-puccinia-suaveolens-causing-leaf-rust-on-cirsium-setosum-in-china
#6
JOURNAL ARTICLE
Cangjuan Liang, Ping Wang, Zehan Wang, Na Zhao, Xuemei Li, Jingyu Li, Lirong Zhang, Qingfang Meng, Hongfei Yan
Thistle, Cirsium setosum (Willd.) M. Bieb., is widely distributed in China as a common weed in fields. It is also used as a traditional Chinese medicine for cooling blood, stopping bleeding, dispelling stasis, detoxifying, and resolving carbuncle. In 2023, we found a rust disease on plants of Cirsium setosum in the experimental field of Hebei Agricultural University, Baoding, Hebei Province, China, with incidence of 15% - 25% (Fig. S1 A, B). The diseased leaves turned yellow, and the leaf edges were slightly rolled...
January 4, 2024: Plant Disease
https://read.qxmd.com/read/37968303/a-chromosome-level-genome-assembly-of-the-knoxia-roxburghii-rubiaceae
#7
JOURNAL ARTICLE
Yingmin Zhang, Fan Zhang, Ling Jin, Ticao Zhang, Xinying Pu, Bin Qiu, Guodong Li
Knoxia roxburghii is a well-known medicinal plant that is widely distributed in southern China and Southeast Asia. Its dried roots, known as hongdaji in traditional Chinese medicine, are used to treat a range of diseases, including cancers, carbuncles, and ascites. In this study, we report a de novo chromosome-level genome sequence for this diploid plant, which has a length of approximately 446.30 Mb with a contig N50 size of 42.26 Mb and scaffold N50 size of 44.38 Mb. Approximately 99...
November 15, 2023: Scientific Data
https://read.qxmd.com/read/37930333/coptisine-the-characteristic-constituent-from-coptis-chinensis-exhibits-significant-therapeutic-potential-in-treating-cancers-metabolic-and-inflammatory-diseases
#8
JOURNAL ARTICLE
Qiang Lu, Ying Tang, Shuang Luo, Qihai Gong, Cailan Li
Naturally derived alkaloids belong to a class of quite significant organic compounds. Coptisine, a benzyl tetrahydroisoquinoline alkaloid, is one of the major bioactive constituents in Coptis chinensis Franch., which is a famous traditional Chinese medicine. C. chinensis possesses many kinds of functions, including the ability to eliminate heat, expel dampness, purge fire, and remove noxious substances. In Asian countries, C. chinensis is traditionally employed to treat carbuncle and furuncle, diabetes, jaundice, stomach and intestinal disorders, red eyes, toothache, and skin disorders...
November 4, 2023: American Journal of Chinese Medicine
https://read.qxmd.com/read/37859314/tinosporae-radix-a-review-of-traditional-use-botany-phytochemistry-bioactivity-and-quality-marker
#9
JOURNAL ARTICLE
Xiaotong Jia, Xiaogen Ma, Pengfei Liu
BACKGROUND: Tinosporae radix is the root tuber of Tinospora capillipes Gagnep of the Menispermaceae family. It has the effects of clearing away heat and toxins, benefiting the throat, relieving pain, and treating sore throat, carbuncle and boils, and other diseases in clinical practice. METHODS: The related references about T. radix in this review were collected by online databases, including PubMed, Elsevier, Web of Science, Willy, SciFinder, SpringLink, Google Scholar, Baidu Scholar, ACS publications, Scopus, and CNKI...
October 6, 2023: Combinatorial Chemistry & High Throughput Screening
https://read.qxmd.com/read/37830052/various-types-of-wounds-that-diabetic-patients-can-develop-a-narrative-review
#10
REVIEW
Suriadi Jais
Diabetic foot complications represent a substantial health burden and are the foremost cause of hospitalization in patients with diabetes. Diabetes mellitus (DM) is known to cause several other problems. Diabetes is rapidly becoming the leading cause of illness and death worldwide. Diabetic foot ulcers (DFU) are one of the most painful complications of diabetes. These complications cause problems in blood vessels, nerves, and other organs throughout the body. DFU pathophysiology is attributed to a triad of neuropathies, trauma with secondary infection, and arterial occlusive disease...
2023: Clinical pathology
https://read.qxmd.com/read/37773648/efficacy-and-adverse-reactions-of-dahuang-mudan-decoction-combined-with-laparoscopy-in-the-treatment-of-appendicitis-a-meta-analysis
#11
JOURNAL ARTICLE
Shengbo Cong, Guangli Wu, Yuanbo Jin, Lijun Zhu
BACKGROUND: Appendicitis is a common acute abdominal disease. Traditional Chinese medicine believes that acute appendicitis is caused by the accumulation of heat and toxin, and the formation of carbuncle and pus in the colon due to stasis. Therefore, treatment should be carried out to clear heat and detoxify, clear the organs, and eliminate carbuncle. Dahuang Mudan Tang contains various traditional Chinese medicines for clearing heat and detoxifying, which can be used to treat appendicitis...
September 29, 2023: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/37741217/epizootological-monitoring-of-some-bacterial-infectious-diseases-of-animals-on-the-territory-of-the-republic-of-kazakhstan
#12
JOURNAL ARTICLE
Zhumagul Kirimbayeva, Aspen Abutalip, Assiya Mussayeva, Gulnur Kuzembekova, Natalya Yegorova
The presence of significant areas used for pastures in Kazakhstan makes it relevant to study the epizootic situation in terms of the incidence of animals during their grazing. The most frequent and dangerous diseases during this period are clostridiosis and listeriosis, which cause significant damage to livestock. Monitoring studies of the dynamics of morbidity among animals for infectious diseases during the grazing period were carried out on the basis of veterinary reporting. Bacteriological studies were carried out in a state laboratory using generally accepted microbiological methods...
September 9, 2023: Comparative Immunology, Microbiology and Infectious Diseases
https://read.qxmd.com/read/37491834/risk-factors-for-treatment-failure-in-neonates-with-skin-and-soft-tissue-infection-a-retrospective-cohort-study
#13
JOURNAL ARTICLE
Purva Patel, Catherine E Foster, Grant Stimes, Su Rin Lee, Sowdhamini S Wallace
We aimed to describe the frequency of treatment failure and associated risk factors for treatment failure amongst neonates with skin and soft tissue infections (SSTIs). We conducted a retrospective cohort study of neonates 0 to 28 days old with uncomplicated SSTIs presenting to the emergency department of a quaternary care children's hospital from 2009 to 2017. Data were collected via chart review. Skin and soft tissue infections included the following: cellulitis, abscess, mastitis, perirectal SSTI, carbuncle, and furuncle...
July 25, 2023: Clinical Pediatrics
https://read.qxmd.com/read/37474332/-examining-fermented-mustard-brine-in-terms-of-traditional-chinese-medicine
#14
JOURNAL ARTICLE
Q W Shi, N Zeng, C Y Wu
Fermented mustard brine was a unique liquid fermented with mustard long used in traditional Chinese medicine. It was previously known as Ji Shui, which refered to the yellow salty water after vegetables were fermented. Fermented mustard brine was not established in TCM until the Ming Dynasty. It was found that the original plant of ancient mustard was Brassica juncea (L.) Czern et Coss. var. juncea, and the origin of the mustard used in mustard brine mainly refereed to the cultivated species of Brassica ( Brassica juncea var...
May 28, 2023: Zhonghua Yi Shi za Zhi, Chinese Journal of Medical History
https://read.qxmd.com/read/37401714/-complex-therapy-and-prevention-of-exacerbations-of-calculous-pyelo-nephritis
#15
JOURNAL ARTICLE
T I Derevyanko, S V Pridchin, E V Ryzhkova
Urolithiasis in Russia still occupies one of the leading places in the total number of urological nosologies. Acute and chronic calculous pyelonephritis is the most severe complication of urolithiasis, causing destructive kidney damage in the form of apostematous pyelonephritis, abscess, kidney carbuncle and pionephrosis. In the case of acute obstruction of the urinary tract by concretion, purulent kidney damage occurs in a very short period of time and the result of treatment in this case depends on the adequacy and speed of the choice of the method of drainage of the urinary tract, that is, the elimination of their obstruction, as well as the correct choice of rational antibacterial therapy...
May 2023: Urologii︠a︡
https://read.qxmd.com/read/37291932/-clinical-analysis-of-patients-with-oral-and-maxillofacial-infections-in-oral-emergency
#16
JOURNAL ARTICLE
Z Wang, W Sun, X Yang, Y Song, A P Ji, J Bai
OBJECTIVE: To analyze the composition, incidence and clinical characteristics of oral and maxillofacial infections in oral emergency. METHODS: A retrospective study on patients with oral and maxillofacial infections who visited the Department of Oral Emergency in Peking University School and Hospital of Stomatology from January 2017 to December 2019 was conducted. General characteristics, such as disease composition, gender, age distribution and position of involved teeth were analyzed...
June 18, 2023: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://read.qxmd.com/read/37241730/identification-of-daphne-genkwa-and-its-vinegar-processed-products-by-ultraperformance-liquid-chromatography-quadrupole-time-of-flight-mass-spectrometry-and-chemometrics
#17
JOURNAL ARTICLE
Hongying Mi, Ping Zhang, Lingwen Yao, Huiyuan Gao, Feng Wei, Tulin Lu, Shuangcheng Ma
Crude herbs of Daphne genkwa (CHDG) are often used in traditional Chinese medicine to treat scabies baldness, carbuncles, and chilblain owing to their significant purgation and curative effects. The most common technique for processing DG involves the use of vinegar to reduce the toxicity of CHDG and enhance its clinical efficacy. Vinegar-processed DG (VPDG) is used as an internal medicine to treat chest and abdominal water accumulation, phlegm accumulation, asthma, and constipation, among other diseases. In this study, the changes in the chemical composition of CHDG after vinegar processing and the inner components of the changed curative effects were elucidated using optimized ultrahigh-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS)...
May 9, 2023: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/37161813/-study-on-the-explicitation-of-implicit-knowledge-and-the-construction-of-knowledge-graph-on-moxibustion-in-medical-case-records-of-zhou-mei-sheng-s-jiusheng
#18
JOURNAL ARTICLE
Bing-Yuan Zhou, Cai-Feng Zhu, Meng Li, Na Zhang, Yu-Mei Jia, An-Qi Wu
To explore the methods of the explicitation of implicit knowledge and the construction of knowledge graph on moxibustion in medical case records of ZHOU Mei - sheng 's Jiusheng . The medical case records data of Jiusheng was collected, the frequency statistic was analyzed based on Python3.8.6, complex network analysis was performed using Gephi9.2 software, community analysis was performed by the ancient and modern medical case cloud platform V2.3.5, and analysis and verification of correlation graph and weight graph were proceed by Neo4j3...
May 12, 2023: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://read.qxmd.com/read/37089949/the-pharmacology-and-mechanisms-of-platycodin-d-an-active-triterpenoid-saponin-from-platycodon-grandiflorus
#19
REVIEW
Long Xie, Yu-Xin Zhao, Yu Zheng, Xiao-Fang Li
Chinese doctors widely prescribed Platycodon grandiflorus A. DC. (PG) to treat lung carbuncles in ancient China. Modern clinical experiences have demonstrated that PG plays a crucial role in treating chronic pharyngitis, plum pneumonia, pneumoconiosis, acute and chronic laryngitis, and so forth. Additionally, PG is a food with a long history in China, Japan, and Korea. Furthermore, Platycodin D (PLD), an oleanane-type triterpenoid saponin, is one of the active substances in PG. PLD has been revealed to have anti-inflammatory, anti-viral, anti-oxidation, anti-obesity, anticoagulant, spermicidal, anti-tumor etc...
2023: Frontiers in Pharmacology
https://read.qxmd.com/read/37005273/a-fatal-case-of-disseminated-infection-caused-by-community-associated-methicillin-resistant-staphylococcus-aureus-usa300-clone
#20
JOURNAL ARTICLE
Hiroyuki Ote, Hideyuki Ito, Taroh Akira, Motoyuki Sugai, Junzo Hisatsune, Yuki Uehara, Yuichiro Oba
Methicillin-resistant Staphylococcus aureus (MRSA) USA300 is a representative community-associated MRSA (CA-MRSA) clone around the world. We herein report a patient of USA300 clone infection who could not be saved. A 25-year-old man who had sex with men presented with fever lasting one week and skin lesions on the buttocks. Computed tomography imaging showed the findings of multiple nodules and consolidations, especially in the peripheral lung fields, right iliac vein thrombosis, and pyogenic myositis of bilateral medial thighs...
March 31, 2023: Japanese Journal of Infectious Diseases
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