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Refeeding syndrome

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https://www.readbyqxmd.com/read/28151828/nutrition-in-the-critically-ill-patient
#1
Kristine W A C Koekkoek, Arthur R H van Zanten
PURPOSE OF REVIEW: To summarize recent relevant studies regarding nutrition during critical illness and provide recommendations for clinical practice. RECENT FINDINGS: Recently acquired knowledge regarding nutritional status and risk assessment, body composition, gastric residual volume, prokinetics, tube positioning, enteral vs parenteral nutrition, nutritional dose and timing of initiation, pharmaconutrition, dysbiosis and probiotics are discussed. SUMMARY: Body composition especially lean body mass is associated with clinical outcomes...
February 1, 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/28087222/revisiting-the-refeeding-syndrome-results-of-a-systematic-review
#2
Natalie Friedli, Zeno Stanga, Lubos Sobotka, Alison Culkin, Jens Kondrup, Alessandro Laviano, Beat Mueller, Philipp Schuetz
OBJECTIVE: Although described >70 y ago, the refeeding syndrome (RFS) remains understudied with lack of standardized definition and treatment recommendations. The aim of this systematic review was to gather evidence regarding standardized definition, incidence rate and time course of occurrence, association with adverse clinical outcomes, risk factors, and therapeutic strategies to prevent or treat this condition. METHODS: We searched MEDLINE and EMBASE for interventional and observational clinical trials focusing on RFS, excluding case reports and reviews...
June 8, 2016: Nutrition
https://www.readbyqxmd.com/read/28073792/adult-parenteral-nutrition-in-the-north-of-england-a-region-wide-audit
#3
Jessica K Dyson, Nick Thompson
OBJECTIVES: Parenteral nutrition (PN) is widely used to provide nutritional support to patients with inaccessible or inadequate length of gut or non-functioning gut. The objective was to compare practice in PN administration to results of the National Confidential Enquiry into Patient Outcome and Death (NCEPOD) report, 'A Mixed Bag', and to establish whether good practice was being followed within this part of the UK. SETTING: Using the Northern Nutrition Network (NNN), we examined the care of adult patients receiving PN in all 10 secondary care hospitals in our region...
January 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28070675/-refeeding-syndrome-in-geriatric-patients-a-frequently-overlooked-complication
#4
Rainer Wirth, Rebecca Diekmann, Olga Fleiter, Leonhardt Fricke, Annika Kreilkamp, Mirja Katrin Modreker, Christian Marburger, Stefan Nels, Rolf Schaefer, Heinz-Peter Willschrei, Dorothee Volkert
The refeeding syndrome is a life-threatening complication that can occur after initiation of a nutrition therapy in malnourished patients. If the risk factors and pathophysiology are known, the refeeding syndrome can effectively be prevented and treated, if recognized early. A slow increase of food intake and the close monitoring of serum electrolyte levels play an important role. Because the refeeding syndrome is not well known and the symptoms may vary extremely, this complication is poorly recognized, especially against the background of geriatric multimorbidity...
January 9, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28031190/risk-factors-for-death-in-children-during-inpatient-treatment-of-severe-acute-malnutrition-a-prospective-cohort-study
#5
Maren Jh Rytter, Esther Babirekere-Iriso, Hanifa Namusoke, Vibeke B Christensen, Kim F Michaelsen, Christian Ritz, Charlotte G Mortensen, Ezekiel Mupere, Henrik Friis
BACKGROUND: Children who receive in-hospital treatment of severe acute malnutrition often have high mortality rates, and the reasons are not well understood. OBJECTIVE: We assessed risk factors for death in children who were treated for malnutrition in a hospital. DESIGN: In a prospective observational study of 120 children who were receiving in-hospital treatment of severe acute malnutrition in Uganda with therapeutic formulas F-75 and F-100, we collected data on symptoms, clinical findings, plasma markers of refeeding syndrome (electrolytes and phosphate), and acute phase reactants, and recorded the nutritional therapy given in hospital...
December 28, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28018595/outcomes-of-an-inpatient-refeeding-protocol-in-youth-with-anorexia-nervosa-and-atypical-anorexia-nervosa-at-children-s-hospitals-and-clinics-of-minnesota
#6
Kathryn Smith, Julie Lesser, Beth Brandenburg, Andrew Lesser, Jessica Cici, Robert Juenneman, Amy Beadle, Sarah Eckhardt, Elin Lantz, James Lock, Daniel Le Grange
BACKGROUND: Historically, inpatient protocols have adopted relatively conservative approaches to refeeding in Anorexia Nervosa (AN) in order to reduce the risk of refeeding syndrome, a potentially fatal constellation of symptoms. However, increasing evidence suggests that patients with AN can tolerate higher caloric prescriptions during treatment, which may result in prevention of initial weight loss, shorter hospital stays, and less exposure to the effects of severe malnutrition. Therefore the present study sought to examine the effectiveness of a more accelerated refeeding protocol in an inpatient AN and atypical AN sample...
2016: Journal of Eating Disorders
https://www.readbyqxmd.com/read/27941249/deficiency-in-prohormone-convertase-pc1-impairs-prohormone-processing-in-prader-willi-syndrome
#7
Lisa C Burnett, Charles A LeDuc, Carlos R Sulsona, Daniel Paull, Richard Rausch, Sanaa Eddiry, Jayne F Martin Carli, Michael V Morabito, Alicja A Skowronski, Gabriela Hubner, Matthew Zimmer, Liheng Wang, Robert Day, Brynn Levy, Ilene Fennoy, Beatrice Dubern, Christine Poitou, Karine Clement, Merlin G Butler, Michael Rosenbaum, Jean Pierre Salles, Maithe Tauber, Daniel J Driscoll, Dieter Egli, Rudolph L Leibel
Prader-Willi syndrome (PWS) is caused by a loss of paternally expressed genes in an imprinted region of chromosome 15q. Among the canonical PWS phenotypes are hyperphagic obesity, central hypogonadism, and low growth hormone (GH). Rare microdeletions in PWS patients define a 91-kb minimum critical deletion region encompassing 3 genes, including the noncoding RNA gene SNORD116. Here, we found that protein and transcript levels of nescient helix loop helix 2 (NHLH2) and the prohormone convertase PC1 (encoded by PCSK1) were reduced in PWS patient induced pluripotent stem cell-derived (iPSC-derived) neurons...
January 3, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/27909106/refeeding-syndrome
#8
Christian D Pulcini, Stacey Zettle, Arvind Srinath
No abstract text is available yet for this article.
December 2016: Pediatrics in Review
https://www.readbyqxmd.com/read/27875284/parenteral-nutrition-electrolyte-abnormalities-and-associated-factors-before-and-after-nutrition-support-team-initiation
#9
Katie Braun, Anne Utech, Maria Eugenia Velez, Renee Walker
BACKGROUND: Studied since the 1940s, refeeding syndrome still has no universal definition, thus making comparison of studies difficult. Negative outcomes (eg, metabolic abnormalities) may occur with the use of specialized nutrition, such as parenteral nutrition (PN). Less than half of medical institutions have a nutrition support team (NST) managing PN. Interdisciplinary team management of PN may reduce negative outcomes of PN. The objective of this study was to show the value of the NST by measuring differences in PN variables, especially electrolyte abnormalities (EAs), before and after NST initiation at a large medical center and to identify factors associated with EAs among adult subjects receiving PN...
October 18, 2016: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27851333/1698-refeeding-syndrome-in-pancreatic-exocrine-insufficiency-replacement-therapy
#10
Riley Jones, Long Vu, Haroon Ahmed, Edwin Hargitt, Kalpan Desai, Vishal Jivan
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851272/1637-torsades-precipitated-by-refeeding-syndrome-a-case-report-abstract
#11
Joshua Da Silva
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27798779/expanding-the-differential-diagnosis-for-transaminitis-in-patients-with-anorexia-nervosa
#12
Adam C Nadelson, Victor D Babatunde, Eric U Yee, Vilas R Patwardhan
Aminotransferase elevations have been described in patients with anorexia nervosa. Hypothesized etiologies have included ischemic hepatitis, refeeding-induced transaminitis, and the process of autophagy. Supervised enteral nutrition is the mainstay of treatment for severe anorexia, but an increase in aminotransferase levels after initiation of enteral feeding presents clinicians with a diagnostic dilemma. We present a 31-year-old woman with anorexia nervosa (body mass index [BMI] of 13.5 kg/m(2)) who experienced a worsening of aminotransferase elevations even after the initiation of enteral feeding...
October 31, 2016: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/27682582/incidence-and-risk-factors-of-refeeding-syndrome-in-head-and-neck-cancer-patients-an-observational-study
#13
Stine Ostenfeldt Rasmussen, Marianne Boll Kristensen, Irene Wessel, Jens Rikardt Andersen
This study aimed to determine the incidence rates of refeeding phenomena (defined as a decline in p-phosphate) and refeeding syndrome (RFS; defined as development of clinical symptoms in addition to a decline in p-phosphate) in head and neck cancer patients, and to identify risk factors. Fifty-four head and neck cancer patients referred for surgery were included. Forty-six potential risk factors were registered at the baseline, and p-phosphate was measured at Days 2, 4, and 7. Eleven patients (20%) developed RFS, and twenty-eight (52%) developed refeeding phenomena...
November 2016: Nutrition and Cancer
https://www.readbyqxmd.com/read/27544004/hyperglycemia-and-subsequent-torsades-de-pointes-with-marked-qt-prolongation-during-refeeding
#14
Takashi Nakashima, Tomoki Kubota, Nobuhiro Takasugi, Yuichiro Kitagawa, Takahiro Yoshida, Hiroaki Ushikoshi, Masanori Kawasaki, Kazuhiko Nishigaki, Shinji Ogura, Shinya Minatoguchi
OBJECTIVE: A fatal cardiac complication can occasionally present in malnourished patients during refeeding; this is known as refeeding syndrome. However, to our knowledge, hyperglycemia preceding torsades de pointes with QT prolongation during refeeding has not been reported. In the present study, we present a case in which hyperglycemia preceded torsades de pointes with QT prolongation during refeeding. The aim of this study was to determine the possible mechanism underlying QT prolongation during refeeding and indicate how to prevent it...
January 2017: Nutrition
https://www.readbyqxmd.com/read/27513485/-not-available
#15
José Manuel Marugán de Miguelsanz, María Del Carmen Torres Hinojal, María Soraya Geijo Uribe, María Paz Redondo Del Río, Beatriz Mongil López, Inés De Brito García-Sousa, Irene Caballero Sanz, José María Eiros Bouza
Anorexia nervosa (AN) is the most prevalent of eating disorders in children and adolescents, and its treatment is long and complex, involving a multidisciplinary team. Nutritional rehabilitation and restoration of a healthy body weight is one of the central goals in the initial stages of inpatient treatment. However, current recommendations on initial energy requirements for these patients are inconsistent, with a clear lack of controlled studies, available scientific evidence and global consensus on the most effective and safe refeeding practices in hospitalized adolescents with anorexia nervosa (AN)...
June 30, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/27491261/-endocrine-and-metabolic-emergencies-points-of-initial-management-topics-vi-emergency-treatment-for-eating-disorders-and-refeeding-syndrome
#16
Mari Hotta Suzuki
No abstract text is available yet for this article.
April 10, 2016: Nihon Naika Gakkai Zasshi. the Journal of the Japanese Society of Internal Medicine
https://www.readbyqxmd.com/read/27452747/-prevention-and-management-of-refeeding-syndrome-in-patients-with-chronic-critical-illness
#17
Jun Chen, Chaogang Fan
Nutritional support is an important means to treat the patients with chronic critical illness for commonly associated malnutrition. Refeeding syndrome is a serious complication during the process, mainly manifested as severe electrolyte with hypophosphataemia being the most common. Refeeding syndrome is not uncommon but it is often ignored. In our future clinical work, we need to recognize this chinical situation and use preventative and treatment measures. According to NICE clinical nutrition guideline, we discussed the risk factors, treatment methods and preventive measures of refeeding syndrome in patients with chronic critical illness...
July 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27444457/-not-available
#18
José Manuel Marugán de Miguelsanz, María Del Carmen Torres Hinojal, María Soraya Geijo Uribe, María Paz Redondo Del Río, Beatriz Mongil López, Inés De Brito García-Sousa, Irene Caballero Sanz, José María Eiros Bouza
Anorexia nervosa (AN) is the most prevalent of eating disorders in children and adolescents, and its treatment is long and complex, involving a multidisciplinary team. Nutritional rehabilitation and restoration of a healthy body weight is one of the central goals in the initial stages of inpatient treatment. However, current recommendations on initial energy requirements for these patients are inconsistent, with a clear lack of controlled studies, available scientific evidence and global consensus on the most effective and safe refeeding practices in hospitalized adolescents with anorexia nervosa (AN)...
2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/27412982/refeeding-syndrome-a-forgotten-and-potentially-lethal-entity
#19
Y Aissaoui, S Hammi, R Tagajdid, K Chkoura, M Boughalem
Refeeding syndrome (RS) is defined as the fluid, electrolyte, metabolic, and clinical disturbances that occur after nutrition of patients who have been undernourished or fasting for a prolonged period. This syndrome has been recognized for several decades but is most often overlooked and underdiagnosed by health professionals. The authors report a RS in a patient subjected to prolonged fasting after being kidnapped by a criminal gang. Refeeding resulted in severe hypophosphatemia, neurological impairments, and hematologic disorders...
May 1, 2016: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/27389547/febrile-neutropenia-and-refeeding-syndrome
#20
H K Jahn, S Barraclough, S Currell, M P Tighe
We describe the management of a 4-year-old child with acute lymphoblastic leukaemia (ALL) who presented with febrile neutropenia, Cryptosporidium and subsequently developed refeeding syndrome. Febrile neutropenia is common and can be life-threatening and we highlight the identification of well low-risk neutropenic children with resolved febrile illnesses suitable for early discharge. We also discuss the potential management strategies for Cryptosporidium Refeeding syndrome is not common, but should be considered as a cause of acute inpatient deterioration and is a significant risk, with potential morbidity, in children who have undergone a period of catabolism...
December 2016: Archives of Disease in Childhood. Education and Practice Edition
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