keyword
MENU ▼
Read by QxMD icon Read
search

Multiple sclerosis diagnosis

keyword
https://www.readbyqxmd.com/read/29785316/a-pediatric-case-of-relapsing-remitting-multiple-sclerosis-onset-following-varicella-zoster-ophthalmicus-with-optic-neuritis
#1
Naoko Shiba, Yuji Inaba, Mitsuo Motobayashi, Makoto Nishioka, Yoichiro Kawasaki, Shunsuke Noda, Hiroki Matsuura, Norimoto Kobayashi, Takafumi Matsuoka, Akinori Nakamura, Yozo Nakazawa
Some epidemiological studies have implied a pathogenetic association between varicella zoster virus (VZV) and multiple sclerosis (MS); this, however, remains controversial. The present report describes a case involving an immunocompetent 10-year-old girl who developed relapsing-remitting MS following the prolonged reactivation of VZV inside the first branch of the trigeminal nerve, exhibiting herpes zoster ophthalmicus with severe optic neuritis. Symptoms related to herpes zoster ophthalmicus and MS appeared consecutively in the 10-week period after the appearance of vesicles...
2018: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/29785228/evaluating-the-utility-of-a-structured-clinical-protocol-for-reducing-the-impact-of-behavioural-and-psychological-symptoms-of-dementia-in-progressive-neurological-diseases-a-pilot-study
#2
Nicholas P Ryan, Laura Scott, Maryanne McPhee, Susan Mathers, Marie-Claire Davis, Roxanne Maule, Fiona Fisher
Objectives: Behavioural and psychological symptoms of dementia (BPSD) cause significant distress to both aged care residents and staff. Despite the high prevalence of BPSD in progressive neurological diseases (PNDs) such as multiple sclerosis, Huntington's disease, and Parkinson's disease, the utility of a structured clinical protocol for reducing BPSD has not been systematically evaluated in PND populations. Method: Staff ( n = 51) and individuals with a diagnosis of PND ( n = 13) were recruited into the study, which aimed to evaluate the efficacy of a PND-specific structured clinical protocol for reducing the impact of BPSD in residential aged care (RAC) and specialist disability accommodation (SDA) facilities...
2018: Behavioural Neurology
https://www.readbyqxmd.com/read/29784250/update-on-pediatric-onset-multiple-sclerosis
#3
REVIEW
A Ruet
Pediatric-onset multiple sclerosis (POMS) has distinctive features compared with adult-onset multiple sclerosis (AOMS), and warrants caution despite being a rare form of MS. POMS diagnostic criteria are somewhat different from those used in AOMS, with acute disseminated encephalomyelitis being a key differential diagnosis of MS in children. Other differential diagnoses that have to be ruled out before diagnosing MS include demyelinating syndromes, autoimmune and systemic pathologies, and infectious, genetic, metabolic and neoplastic diseases...
May 18, 2018: Revue Neurologique
https://www.readbyqxmd.com/read/29784249/multiple-sclerosis-biomarkers-helping-the-diagnosis
#4
REVIEW
E Thouvenot
Multiple sclerosis (MS) is a complex heterogeneous disease. Diagnostic criteria are based on symptoms, biomarkers, MRI data and exclusion of differential diagnoses. Over the past few years, the usefulness of biomarkers has progressively decreased with the development of new MRI criteria, yet dozens of new biomarkers, especially in cerebrospinal fluid, for MS diagnosis and prognosis have been described. Large-scale studies validating some of these new biomarkers have also provided confirmation of a restricted set of biomarkers (presented here in this review) as having potential value for different stages of the disease, including as early as clinically isolated syndrome and radiologically isolated syndrome...
May 18, 2018: Revue Neurologique
https://www.readbyqxmd.com/read/29784248/conventional-and-advanced-mri-in-multiple-sclerosis
#5
REVIEW
C Louapre
Magnetic resonance imaging (MRI) plays a central role in the management of patients with multiple sclerosis (MS). T2-weighted/FLAIR lesions have been included in the diagnostic criteria since 2001, and the importance of the technology has been expanded in each successive revision of the McDonald criteria. While the typical focal hyperintense lesions seen on T2 and FLAIR sequences in several areas of the central nervous system are key features for MS diagnosis, they can also be used to monitor disease activity, particularly in asymptomatic patients, and to evaluate therapeutic responses...
May 18, 2018: Revue Neurologique
https://www.readbyqxmd.com/read/29782307/cutaneous-manifestations-of-tuberous-sclerosis
#6
Mirjana Bakić, Marina Ratković, Branka Gledović, Balsa Vujović, Danilo Radunović, Vera Babić, Vladimir Prelević
Dear Editor, Tuberous sclerosis (TS) is an autosomal dominant multisystem disease, which occurs due to genetically determined hyperplasia of ectodermal and mesodermal cells. Clinical manifestations present on the skin and in the nervous system, kidneys, heart, and other organs. Recent studies estimate the incidence of TS at 1/6000 to 1/10,000 live births, and a prevalence in the general population of approximately 1 in 20,000 (1). There are two different genetic loci responsible for TS: 9q34 (TSC1-hamartin) and 16p13...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29780612/the-sound-of-jacqueline-du-pr%C3%A3-revisiting-her-medical-and-musical-history
#7
REVIEW
Luis Octavio Tierradentro-García, Juan Sebastián Botero-Meneses, Claudia Talero-Gutiérrez
Jacqueline du Pré was a British cellist, famous for her masterful interpretations and her passionate style of playing. Her outstanding musical career was, unfortunately, cut short by multiple sclerosis. In the present paper, we conduct a historical and medical analysis of her life story, discussing a few aspects regarding her illness and treatment options available at the time of her diagnosis.
April 2018: Multiple Sclerosis Journal—Experimental, Translational and Clinical
https://www.readbyqxmd.com/read/29778042/reliability-and-validity-of-the-dymus-questionnaire-for-the-assessment-of-dysphagia-in-multiple-sclerosis-greek-version-and-proposed-modification
#8
Athanasia Printza, Maria Kalaitzi, Christos Bakirtzis, Ioannis Nikolaidis, Hariklia Proios, Nikolaos Grigoriadis
BACKGROUND: Recent research confirmed that at least a third of people with multiple sclerosis (MS) are suffering from swallowing difficulties. Dysphagia is associated with significant morbidity and mortality, and has profound impact on physical ability and quality of life. Dysphagia related complications can be prevented through an effective screening protocol. The Dysphagia in Multiple Sclerosis (DYMUS) questionnaire is the first dysphagia questionnaire developed specifically for patients with MS...
May 10, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29775086/healthcare-utilization-and-costs-of-multiple-sclerosis-patients-in-the-netherlands-a-healthcare-claims-database-study
#9
Servaas Buijs, Marieke Krol, Gert de Voer
AIM: To investigate the incidence and prevalence and healthcare costs of multiple sclerosis (MS) in the Netherlands by using healthcare claims data. MATERIALS & METHODS: A claims database was analyzed including 26% of the Dutch population. RESULTS: Average prevalence of MS in the Netherlands was 88 per 100,000 inhabitants (males 48, 127 females) and incidence nine per 100,000. Yearly per patient medication costs were highest in the year after the first MS claim and then decreased...
May 18, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29774770/high-neurofilament-levels-are-associated-with-clinically-definite-multiple-sclerosis-in-children-and-adults-with-clinically-isolated-syndrome
#10
Roos M van der Vuurst de Vries, Yu Yi M Wong, Julia Y Mescheriakova, E Daniëlle van Pelt, Tessel F Runia, Naghmeh Jafari, Theodora Am Siepman, Marie-José Melief, Annet F Wierenga-Wolf, Marvin M van Luijn, Johnny P Samijn, Rinze F Neuteboom, Rogier Q Hintzen
BACKGROUND: A promising biomarker for axonal damage early in the disease course of multiple sclerosis (MS) is neurofilament light chain (NfL). It is unknown whether NfL has the same predictive value for MS diagnosis in children as in adults. OBJECTIVE: To explore the predictive value of NfL levels in cerebrospinal fluid (CSF) for MS diagnosis in paediatric and adult clinically isolated syndrome (CIS) patients. METHODS: A total of 88 adult and 65 paediatric patients with a first attack of demyelination were included and followed (mean follow up-time in adults: 62...
May 1, 2018: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/29772467/yawning-and-cortisol-levels-in-multiple-sclerosis-potential-new-diagnostic-tool
#11
Simon B N Thompson, Alister Coleman, Nicola Williams
Yawning is a significant behavioural response and, together with cortisol, is potentially a new diagnostic marker of neurological diseases. Evidence of an association between yawning and cortisol was found which supports the Thompson Cortisol Hypothesis and thermoregulation hypotheses, indication that brain cooling occurs when yawning. 117 volunteers aged 18-69 years were randomly allocated to experimentally controlled conditions to provoke yawning. Thirty-three had been diagnosed with multiple sclerosis. Saliva cortisol samples were collected before and after yawning or after stimuli presentation in the absence of yawning...
May 2, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29772404/viremia-preceding-multiple-sclerosis-two-nested-case-control-studies
#12
Emilie Hultin, Laila Sara Arroyo Mühr, Zurab Bzhalava, Maria Hortlund, Camilla Lagheden, Peter Sundström, Joakim Dillner
Infections have been suggested to be involved in Multiple Sclerosis (MS). We used metagenomic sequencing to detect both known and yet unknown microorganisms in 2 nested case control studies of MS. Two different cohorts were followed for MS using registry linkages. Serum samples taken before diagnosis as well as samples from matched control subjects were selected. In cohort1 with 75 cases and 75 controls, most viral reads were Anelloviridae-related and >95% detected among the cases. Among samples taken up to 2 years before MS diagnosis, Anellovirus species TTMV1, TTMV6 and TTV27 were significantly more common among cases...
May 14, 2018: Virology
https://www.readbyqxmd.com/read/29768251/balo-s-concentric-sclerosis-an-update-and-comprehensive-literature-review
#13
Ali Amini Harandi, Akram Esfandani, Hossein Pakdaman, Mehdi Abbasi, Mohammad Ali Sahraian
Balo's concentric sclerosis (BCS) is considered a variant of multiple sclerosis characterized by concentric lamella of alternating demyelinated and partially myelinated tissues. It is a rare and a relatively acute condition. Attacks may proceed rapidly over weeks or months, typically without remission, like Marburg's variant, resulting in death or severe disability. However, the majority of cases have a more benign, self-limiting course with spontaneous remission. Magnetic resonance imaging is a primary imaging modality in the diagnosis of BCS...
May 16, 2018: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/29762077/impact-of-the-2017-revisions-to-mcdonald-criteria-on-the-diagnosis-of-multiple-sclerosis
#14
Rebecca Beesley, Valerie Anderson, Katharine E Harding, Fady Joseph, Valentina Tomassini, Trevor P Pickersgill, Neil P Robertson, Emma C Tallantyre
No abstract text is available yet for this article.
May 1, 2018: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/29753357/personal-income-before-and-after-diagnosis-of-multiple-sclerosis
#15
Erik Landfeldt, Anna Castelo-Branco, Axel Svedbom, Emil Löfroth, Andrius Kavaliunas, Jan Hillert
BACKGROUND: Multiple sclerosis (MS) is associated with serious morbidity and labor force absenteeism, but little is known of the long-term impact of the disease on personal income. OBJECTIVES: To assess long-term consequences of MS on personal salary and disposable income. METHODS: Patients with MS in Sweden were identified in a nationwide, disease-specific register and matched with general population controls. We assessed mean annual personal gross salary and disposable income each year before and after index (i...
May 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/29750884/nutritional-intervention-as-an-essential-part-of-multiple-sclerosis-treatment
#16
A Penesová, Z Dean, B Kollár, A Havranová, R Imrich, M Vlček, Ž Rádiková
Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system. In addition to the genetic, epigenetic and immunological components, various other factors e.g. unhealthy dietary habits play a role in the MS pathogenesis. Dietary intervention is a highly appealing approach, as it presents a simple and relatively low risk method to potentially improve outcomes in patients with brain disorders in order to achieve remission and improvement of clinical status, well-being and life expectancy of patients with MS...
May 10, 2018: Physiological Research
https://www.readbyqxmd.com/read/29747309/-etiological-analysis-on-patients-with-vertigo-or-dizziness
#17
H Xue, Y Chong, Z D Jiang, Z L Liu, L Ding, S L Yang, L Wang, W P Xiang
Objective: To explore the spectrum of causes for patients with vertigo or dizziness in the Department of Neurology, and provide a reference for diagnosis and treatment of patients with vertigo or dizziness. Methods: Clinical data of patients in the Department of Neurology, Baotou Central Hospital between January 2016 and September 2017 was retrospectively analyzed. The target group under study was diagnosed based on the uniform diagnostic criteria. Results: A total of 9 200 patients with a chief complaint of vertigo or dizziness were included...
April 24, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29744874/implications-of-the-international-paediatric-multiple-sclerosis-study-group-consensus-criteria-for-paediatric-acute-disseminated-encephalomyelitis-a-nationwide-validation-study
#18
Magnus S Boesen, Morten Blinkenberg, Nils Koch-Henriksen, Lau C Thygesen, Peter V Uldall, Melinda Magyari, Alfred P Born
AIM: The International Paediatric Multiple Sclerosis Study Group (IPMSSG) has proposed criteria for acute disseminated encephalomyelitis (ADEM) not evaluated in clinical practice. Our objective was to assess epidemiological implications of the IPMSSG criteria for ADEM in a cohort study using prospectively collected data. METHOD: We identified all diagnosed cases of ADEM in Denmark between 2008 and 2015 from the Danish National Patient Register by International Classification of Diseases 10 codes assigned to acute demyelinating episodes, and we reviewed all medical records to validate ADEM...
May 10, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29743325/trajectories-of-disposable-income-among-people-of-working-ages-diagnosed-with-multiple-sclerosis-a-nationwide-register-based-cohort-study-in-sweden-7-years-before-to-4-years-after-diagnosis-with-a-population-based-reference-group
#19
Chantelle Murley, Olof Mogard, Michael Wiberg, Kristina Alexanderson, Korinna Karampampa, Emilie Friberg, Petter Tinghög
OBJECTIVES: To describe how disposable income (DI) and three main components changed, and analyse whether DI development differed from working-aged people with multiple sclerosis (MS) to a reference group from 7 years before to 4 years after diagnosis in Sweden. DESIGN: Population-based cohort study, 12-year follow-up (7 years before to 4 years after diagnosis). SETTING: Swedish working-age population with microdata linked from two nationwide registers...
May 9, 2018: BMJ Open
https://www.readbyqxmd.com/read/29743290/cerebrospinal-fluid-immunoglobulin-light-chain-ratios-predict-disease-progression-in-multiple-sclerosis
#20
Emma Rathbone, Lindsay Durant, James Kinsella, Antony R Parker, Ghaniah Hassan-Smith, Michael R Douglas, S John Curnow
OBJECTIVE: To determine whether the ratio of cerebrospinal fluid (CSF) immunoglobulin kappa to lambda light chains at time of multiple sclerosis (MS) diagnosis predicts disease progression and whether this was intrinsic to CSF plasmablasts. METHODS: CSF and peripheral blood were obtained from patients undergoing elective diagnostic lumbar puncture and included clinically isolated syndrome (CIS) (n=43), relapsing remitting MS (RRMS; n=50), primary progressive MS (PPMS; n=20) and other neurological disease controls, both inflammatory (ONID; n=23) and non-inflammatory (OND; n=114)...
May 9, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
keyword
keyword
27729
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"