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Low Histamine Diet

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https://www.readbyqxmd.com/read/27624921/a-popular-myth-low-histamine-diet-improves-chronic-spontaneous-urticaria-fact-or-fiction
#1
N Wagner, D Dirk, A Peveling-Oberhag, I Reese, U Rady-Pizarro, H Mitzel, P Staubach
BACKGROUND: Chronic spontaneous urticaria (CsU) is a frequent dermatological disease that might last for months or years with high impact on quality of life. Known causes are autoreactive phenomena, infections or intolerances, rarely IgE-mediated allergies. One-third of CsU patients benefit from a low-pseudoallergen diet. Additionally, it is often discussed, that reducing histamine ingestion alone might improve clinical symptoms and quality of life in CsU patients despite the uncertain role of the histamine-degrading enzyme diamine oxidase (DAO)...
September 13, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27329741/histamine-intolerance-in-patients-with-chronic-spontaneous-urticaria
#2
F Siebenhaar, A Melde, M Magerl, T Zuberbier, M K Church, M Maurer
BACKGROUND: Histamine intolerance and pseudoallergy to foods have been suggested to be causes of chronic spontaneous urticaria (CSU) with some patients reporting exacerbation with histamine-rich foods. OBJECTIVE: The study aim was to identify the rate of histamine-intolerant CSU patients and to characterize the relevance of histamine intolerance as an underlying cause of CSU. METHODS: A cohort of 157 of moderate to severe CSU patients (UAS7 ≥ 10) was asked to provide a detailed clinical history, particularly in relation to symptom development after eating histamine-rich foods...
October 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27190751/effect-of-dietary-histamine-supplementation-on-growth-digestive-enzyme-activities-and-morphology-of-intestine-and-hepatopancreas-in-the-chinese-mitten-crab-eriocheir-sinensis
#3
Liulan Zhao, Xiaozhen Yang, Yongxu Cheng, Song Yang
A 28-days feeding experiment was conducted to investigate the effect of histamine on digestive physiology of the Chinese mitten crab, Eriocheir sinensis. Four experimental diets were supplemented with histamine at 0, 1, 2, 4 g/kg. Histamine supplementation had no effect on growth. The activities of digestive enzyme decreased significantly at first (days 7 and 14) (p < 0.05) and then increased or finally slightly recovered in the hepatopancreas and intestinal tract on the 28th day. Tryptase and amylase activities were inhibited significantly in each histamine-treated group on day 7 as compared to the control (p < 0...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27177895/-histamine-intolerance-are-the-criteria-of-an-adverse-reaction-met
#4
Imke Reese
Searching the internet for an explaination of recurring symptoms, many people come across the so-called histamine intolerance disorder. Also many practitioners like to diagnose this disorder without making sure that reproducibility, a prerequisite for an adverse reaction, is present. Consequently, presumably affected persons are often advised to follow a low-histamine diet. Depending on the source of information, these diets often avoid a huge variety of foods containing more or less histamine, which has a considerable impact on patient quality of life...
June 2016: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/26976734/fodmaps-alter-symptoms-and-the-metabolome-of-patients-with-ibs-a-randomised-controlled-trial
#5
Keith McIntosh, David E Reed, Theresa Schneider, Frances Dang, Ammar H Keshteli, Giada De Palma, Karen Madsen, Premysl Bercik, Stephen Vanner
OBJECTIVE: To gain mechanistic insights, we compared effects of low fermentable oligosaccharides, disaccharides and monosaccharides and polyols (FODMAP) and high FODMAP diets on symptoms, the metabolome and the microbiome of patients with IBS. DESIGN: We performed a controlled, single blind study of patients with IBS (Rome III criteria) randomised to a low (n=20) or high (n=20) FODMAP diet for 3 weeks. Symptoms were assessed using the IBS symptom severity scoring (IBS-SSS)...
March 14, 2016: Gut
https://www.readbyqxmd.com/read/26641046/effects-of-high-levels-of-dietary-zinc-oxide-on-ex-vivo-epithelial-histamine-response-and-investigations-on-histamine-receptor-action-in-the-proximal-colon-of-weaned-piglets
#6
RANDOMIZED CONTROLLED TRIAL
S Kröger, R Pieper, J R Aschenbach, L Martin, P Liu, J Rieger, H G Schwelberger, K Neumann, J Zentek
The aim of the study was to identify the effect of high dietary zinc oxide (ZnO) levels on the histamine-induced secretory-type response and histamine metabolism in the porcine proximal colon. After weaning at d 26, 3 diets with low (LZn), normal (NZn), and high (HZn) concentrations of zinc (57, 164, or 2,425 mg/kg) were fed to a total of 120 piglets. Digesta and tissue samples were taken from the ascending colon after 7 ± 1, 14 ± 1, 21 ± 1, and 28 ± 1 d. Partially stripped tissue was mounted in Ussing chambers, and histamine was applied either to the serosal or mucosal compartments...
November 2015: Journal of Animal Science
https://www.readbyqxmd.com/read/26554410/diagnosis-and-treatment-of-gastroesophageal-reflux-in-infants-and-children
#7
Drew C Baird, Dausen J Harker, Aaron S Karmes
Gastroesophageal reflux is defined as the passage of stomach contents into the esophagus with or without accompanied regurgitation (spitting up) and vomiting. It is a normal physiologic process that occurs throughout the day in infants and less often in children and adolescents. Gastroesophageal reflux disease (GERD) is reflux that causes troublesome symptoms or leads to medical complications. The diagnoses of gastroesophageal reflux and GERD are based on the history and physical examination. Diagnostic tests, such as endoscopy, barium study, multiple intraluminal impedance, and pH monitoring, are reserved for when there are atypical symptoms, warning signs, doubts about the diagnosis, or suspected complications or treatment failure...
October 15, 2015: American Family Physician
https://www.readbyqxmd.com/read/26520191/-functional-and-motor-gastrointestinal-disorders
#8
Fermín Mearin, Enrique Rey, Agustín Balboa
This article discusses the most interesting studies on functional and motor gastrointestinal disorders presented at Digestive Diseases Week (DDW), 2015. Researchers are still seeking biomarkers for irritable bowel syndrome and have presented new data. One study confirmed that the use of low-dose antidepressants has an antinociceptive effect without altering the psychological features of patients with functional dyspepsia. A contribution that could have immediate application is the use of transcutaneous electroacupuncture, which has demonstrated effectiveness in controlling nausea in patients with gastroparesis...
September 2015: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/26384956/interventions-for-heartburn-in-pregnancy
#9
REVIEW
Vorapong Phupong, Tharangrut Hanprasertpong
BACKGROUND: Heartburn is one of the most common gastrointestinal symptoms in pregnant women. It can occur in all trimesters of pregnancy. The symptoms of heartburn in pregnancy may be frequent, severe and distressing, but serious complications are rare. Many interventions have been used for the treatment of heartburn in pregnancy. These interventions include advice on diet, lifestyle modification and medications. However, there has been no evidence-based recommendation for the treatment of heartburn in pregnancy...
September 19, 2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/25907487/-macrophage-content-detection-in-an-experimental-rabbit-model-of-atherosclerotic-plaque-by-optical-coherence-tomography
#10
Xiying Yu, Daliang Zhou, Dan Hao, Lin Wei, Bo Yu
OBJECTIVE: To evaluate the feasibility of detecting macrophage content on atherosclerotic plaques by optical coherence tomography (OCT) technique. METHODS: Thirty New Zealand white rabbits were equally divided into 3 groups at random: Control group (fed normal rabbit chow, n = 10); lipid diet group (fed regular chow supplemented with cholesterol, n = 10) and balloon injury+ lipid diet group (balloon catheter injury of the common carotid artery after 2 weeks lipid diet, n = 10)...
February 2015: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/25811595/oxidized-low-density-lipoprotein-contributes-to-atherogenesis-via-co-activation-of-macrophages-and-mast-cells
#11
Chong Chen, Damir B Khismatullin
Oxidized low-density lipoprotein (OxLDL) is a risk factor for atherosclerosis, due to its role in endothelial dysfunction and foam cell formation. Tissue-resident cells such as macrophages and mast cells release inflammatory mediators upon activation that in turn cause endothelial activation and monocyte adhesion. Two of these mediators are tumor necrosis factor (TNF)-α, produced by macrophages, and histamine, produced by mast cells. Static and microfluidic flow experiments were conducted to determine the number of adherent monocytes on vascular endothelium activated by supernatants of oxLDL-treated macrophages and mast cells or directly by oxLDL...
2015: PloS One
https://www.readbyqxmd.com/read/25667239/nonpharmacologic-treatment-of-functional-abdominal-pain-disorders-a-systematic-review
#12
REVIEW
Juliette M T M Rutten, Judith J Korterink, Leonie M A J Venmans, Marc A Benninga, Merit M Tabbers
BACKGROUND AND OBJECTIVE: Various nonpharmacologic treatments are available for pediatric abdominal pain-related functional gastrointestinal disorders (AP-FGIDs). Data on efficacy and safety are scarce. The goal of this study was to summarize the evidence regarding nonpharmacologic interventions for pediatric AP-FGIDs: lifestyle interventions, dietary interventions, behavioral interventions, prebiotics and probiotics, and alternative medicine. METHODS: Searches were conducted of the Medline and Cochrane Library databases...
March 2015: Pediatrics
https://www.readbyqxmd.com/read/25656974/down-regulation-of-monocarboxylate-transporter-1-mct1-gene-expression-in-the-colon-of-piglets-is-linked-to-bacterial-protein-fermentation-and-pro-inflammatory-cytokine-mediated-signalling
#13
COMPARATIVE STUDY
Carmen Villodre Tudela, Christelle Boudry, Friederike Stumpff, Jörg R Aschenbach, Wilfried Vahjen, Jürgen Zentek, Robert Pieper
The present study investigated the influence of bacterial metabolites on monocarboxylate transporter 1 (MCT1) expression in pigs using in vivo, ex vivo and in vitro approaches. Piglets (n 24) were fed high-protein (26 %) or low-protein (18 %) diets with or without fermentable carbohydrates. Colonic digesta samples were analysed for a broad range of bacterial metabolites. The expression of MCT1, TNF-α, interferon γ (IFN-γ) and IL-8 was determined in colonic tissue. The expression of MCT1 was lower and of TNF-α and IL-8 was higher with high-protein diets (P< 0·05)...
February 28, 2015: British Journal of Nutrition
https://www.readbyqxmd.com/read/25581821/novel-function-of-histamine-signaling-in-hyperlipidemia-induced-atherosclerosis-histamine-h1-receptors-protect-and-h2-receptors-accelerate-atherosclerosis
#14
Sohsuke Yamada, Ke-Yong Wang, Akihide Tanimoto, Yasuyuki Sasaguri
Histamine is not only essential for acute inflammatory reactions, but it also participates in a chronic inflammatory disorder. We generated apolipoprotein E (apoE) and histamine receptors (HHRs), including the major H1 and H2 receptors (HH1R, HH2R) double knockout mice (DKO) to clarify the role of HHRs in hyperlipidemia-induced atherosclerosis, in which apoE-KO and DKO mice were fed a high cholesterol diet. We found that pronounced hyperlipidemia-induced atherosclerotic progression occurred in HH1R/apoE-DKO mice, but in HH2R/apoE-DKO mice less atherosclerosis, despite pro-atherogenic serum cholesterol levels compared with apoE-KO mice...
February 2015: Pathology International
https://www.readbyqxmd.com/read/25056690/insufficient-intake-of-l-histidine-reduces-brain-histamine-and-causes-anxiety-like-behaviors-in-male-mice
#15
Takeo Yoshikawa, Tadaho Nakamura, Tetsuro Shibakusa, Mayu Sugita, Fumito Naganuma, Tomomitsu Iida, Yamato Miura, Attayeb Mohsen, Ryuichi Harada, Kazuhiko Yanai
L-histidine is one of the essential amino acids for humans, and it plays a critical role as a component of proteins. L-histidine is also important as a precursor of histamine. Brain histamine is synthesized from L-histidine in the presence of histidine decarboxylase, which is expressed in histamine neurons. In the present study, we aimed to elucidate the importance of dietary L-histidine as a precursor of brain histamine and the histaminergic nervous system. C57BL/6J male mice at 8 wk of age were assigned to 2 different diets for at least 2 wk: the control (Con) diet (5...
October 2014: Journal of Nutrition
https://www.readbyqxmd.com/read/25020133/chronic-ingestion-of-h1-antihistamines-increase-progression-of-atherosclerosis-in-apolipoprotein-e-mice
#16
Vineesh V Raveendran, Donald D Smith, Xiaoyu Tan, Matthew E Sweeney, Gregory A Reed, Colleen A Flynn, Ossama W Tawfik, Ginger Milne, Kottarappat N Dileepan
Although increased serum histamine levels and H1R expression in the plaque are seen in atherosclerosis, it is not known whether H1R activation is a causative factor in the development of the disease, or is a host defense response to atherogenic signals. In order to elucidate how pharmacological inhibition of histamine receptor 1 (H1R) signaling affects atherogenesis, we administered either cetirizine (1 and 4 mg/kg. b.w) or fexofenadine (10 and 40 mg/kg. b.w) to ApoE-/- mice maintained on a high fat diet for three months...
2014: PloS One
https://www.readbyqxmd.com/read/24898510/-debating-histamine-intolerance-are-adverse-reactions-to-histamine-containing-foods-fact-or-fiction
#17
I Reese
Low-histamine diets are very popular and often self-imposed among people suspecting histamine intolerance. Most of these diets avoid a huge variety of foods containing more or less histamine, which has a considerable impact on their quality of life, but in most cases no long-term benefit. Underlying a diminished capacity for histamine degradation, the lack of partial or complete symptom improvement might be due to the fact that endogenous histamine release could also be responsible for symptoms. The role of ingested histamine-below the level for intoxication-is discussed controversially...
June 2014: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/24331700/-changes-in-mast-cells-and-hepatic-expression-of-c-kit-and-stem-cell-factor-in-the-rat-model-of-chronic-hepatitis
#18
Hong Li, Long-feng Zhao, Yan-qin Hao, Lei Yin, Yuan-chang Zhao, De-wu Han
OBJECTIVE: To study the potential role of mast cells and the related molecular mechanism in chronic hepatitis (CH) using a rat model system. METHODS: Thirty Wistar rats (15 males, 15 females; weight range: 230-290 g) were randomly divided into the normal contrast (NC) group and experimental CH group. The CH group received subcutaneous injection of CCl4 and a diet high in cholesterol and alcohol content and low in protein and choline content. Throughout the 4-week modeling period, aseptic blood samples were taken to test plasma tryptase (TS) and hyaluronic acid (HA) levels...
November 2013: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
https://www.readbyqxmd.com/read/24331635/-effects-of-antihistamine-treatment-on-immune-function-in-rats-with-experimental-hepatitis
#19
Hong Li, Long-feng Zhao, Yan-qin Hao, De-wu Han
OBJECTIVE: To investigate the effects of antihistamine treatment on immune function in rats with experimental hepatitis. METHODS: Thirty Wistar rats were randomly allocated into three groups:experimental hepatitis group (EH group), antihistamine treatment group (AH group) and normal control group (NC group). Rats in the EH group received the subcutaneous injection of 40% carbon tetrachloride oil solution and were fed on diet with low-protein, low-choline, high-fat and high-alcohol,while rats in the AH group received antihistamine treatment(ketotifen + vitamin C) additionally...
October 2013: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
https://www.readbyqxmd.com/read/24260435/diets-high-in-heat-treated-soybean-meal-reduce-the-histamine-induced-epithelial-response-in-the-colon-of-weaned-piglets-and-increase-epithelial-catabolism-of-histamine
#20
Susan Kröger, Robert Pieper, Hubert G Schwelberger, Jing Wang, Carmen Villodre Tudela, Jörg R Aschenbach, Andrew G Van Kessel, Jürgen Zentek
We examined the influence of dietary fermentable protein (fCP) and fermentable carbohydrates (fCHO) on the colonic epithelial response to histamine in pigs. Thirty-two weaned piglets were fed 4 diets in a 2 × 2 factorial design with low fCP/low fCHO, low fCP/high fCHO, high fCP/low fCHO and high fCP/high fCHO. After 21-23 days, the pigs were killed and tissue from the proximal colon was stimulated with carbachol, histamine, PGE2 or sodium hydrogen sulphide in Ussing chambers. Changes in short-circuit current and tissue conductance were measured...
2013: PloS One
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