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https://www.readbyqxmd.com/read/28726590/a-method-of-managing-severe-traumatic-brain-injury-in-the-absence-of-intracranial-pressure-monitoring-the-ice-protocol
#1
Randall Chesnut, Nancy Temkin, Sureyya Dikmen, Carlos Rondina, Walter Videtta, Gustavo Petroni, Silvia Lujan, Victor Alanis, Antonio Luis Eiras Falcao, Gustavo La Fuente, Luis Gonzalez, Manuel Jibaja, Arturo Lavendez, Freddy Sandi Lora, Roberto Merida, Ricardo Romero, James Pridgeon, Jason Barber, Joan Machamer, Kelley Chaddock
Purpose - The imaging- and clinical-examination (ICE) algorithm used in the BEST TRIP ICP randomized controlled trial is the only prospectively investigated clinical protocol for TBI management without ICP monitoring. As the default literature standard, it warrants careful evaluation. Methods - We present the ICE protocol in detail and analyse the demographics, outcome, treatment intensity, frequency of intervention usage, and related adverse events in the ICE-protocol cohort. Results - The 167 ICE protocol patients were young (median 29 years) with a median Glasgow Coma Scale motor score of 4 but with anisocoria or abnormal pupillary reactivity in 40%...
July 20, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28708726/measuring-cerebral-hypoperfusion-induced-by-hyperventilation-challenge-with-intravoxel-incoherent-motion-magnetic-resonance-imaging-in-healthy-volunteers
#2
Aude Pavilla, Alessandro Arrigo, Mehdi Mejdoubi, Régis Duvauferrier, Giulio Gambarota, Hervé Saint-Jalmes
OBJECTIVES: The aim of this study was to demonstrate the feasibility to assess cerebral hypoperfusion with a hyperventilation (HV) challenge protocol using intravoxel incoherent motion (IVIM) magnetic resonance imaging. MATERIALS AND METHODS: Magnetic resonance imaging experiments were performed on 10 healthy volunteers at 1.5 T, with a diffusion IVIM magnetic resonance imaging protocol using a set of b-values optimized by Cramer-Rao Lower Bound analysis. Hypoperfusion was induced by an HV maneuver...
July 13, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28699806/fibromyalgia-as-a-cause-of-uncontrolled-asthma-a-case-controlled-multicenter-study
#3
Eva Martinez-Moragon, V Plaza, Isabel Torres, Ana Rosado, Isabel Urrutia, Xavier Casas, Belen Hinojosa, Marina Blanco-Aparicio, Julio Delgado, Santiago Quirce, Carles Sabadell, Pilar Cobellero, Ana Muñoz-Fernández
BACKGROUND: Fibromyalgia can affect the control of asthma when both diseases are present in a single patient. OBJECTIVES: To characterize asthma in patients with concomitant fibromyalgia to assess whether fibromyalgia is an independent factor of asthma severity that influences upon poor asthma control. We also evaluated how dyspnea is perceived by the patients in order to demonstrate that alterations in the perception of airway obstruction may be responsible for poor asthma control...
July 12, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28674596/effects-of-nasal-or-oral-breathing-on-anaerobic-power-output-and-metabolic-responses
#4
Christine Recinto, Theodore Efthemeou, P Tony Boffelli, James W Navalta
Nasal and oral exclusive breathing modes have benefits and drawbacks during submaximal exercise. It is unknown whether these responses would extend to anaerobic work performed at high intensity. Nine individuals (males N = 7, females N = 2) performed a standard Wingate Anaerobic cycle test on a cycle ergometer under nose (N) and mouth (M) only respiratory conditions, performed in a counterbalanced order. A 2 (condition: nose, mouth) × 6 (time: 0-5 sec, 5-10 sec, 10-15 sec, 15-20 sec, 20-25 sec, 25-30 sec) repeated measures ANOVA was used to analyze the data with significance accepted at the p<0...
2017: International Journal of Exercise Science
https://www.readbyqxmd.com/read/28657491/novel-noninvasive-method-of-cerebrovascular-blood-volume-assessment-using-brain-bioimpedance
#5
Mohamad Hakam Tiba, Brendan M McCracken, Sardar Ansari, Ashwin Belle, Brandon C Cummings, Venkatakrishna Rajajee, Parag G Patil, Hasan B Alam, Kevin R Ward
Cerebro-vascular autoregulation (CAR) is the ability of vessels to modulate their tone in response to changes in pressure. CAR, as an auto-protective mechanism is critical in preventing secondary brain injury post trauma. Monitoring of changes in cerebral blood volume might be valuable in evaluating CAR and response to various therapies. In this study, we utilized an ocular-brain bioimpedance interface to assess real time changes in cerebral blood volume in response to a number of physiologic challenges. We hypothesize that changes in brain bioimpedance (dz) would track changes in cerebral blood volume...
June 28, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28642859/exercise-induced-bronchospasm-and-allergy
#6
REVIEW
Serena Caggiano, Renato Cutrera, Antonio Di Marco, Attilio Turchetta
Sport is an essential part of childhood, with precious and acknowledged positive health effects but the impact of exercise-induced bronchoconstriction (EIB) significantly reduces participation in physical activity. It is important to recognize EIB, differentiating EIB with or without asthma if the transient narrowing of the airways after exercise is associated with asthmatic symptoms or not, in the way to select the most appropriate treatment among the many treatment options available today. Therapy is prescribed based on symptoms severity but diagnosis of EIB is established by changes in lung function provoked by exercise evaluating by direct and indirect tests...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28635028/gases-for-establishing-pneumoperitoneum-during-laparoscopic-abdominal-surgery
#7
REVIEW
Tianwu Yu, Yao Cheng, Xiaomei Wang, Bing Tu, Nansheng Cheng, Jianping Gong, Lian Bai
BACKGROUND: This is an update of the review published in 2013.Laparoscopic surgery is now widely performed to treat various abdominal diseases. Currently, carbon dioxide is the most frequently used gas for insufflation of the abdominal cavity (pneumoperitoneum). Although carbon dioxide meets most of the requirements for pneumoperitoneum, the absorption of carbon dioxide may be associated with adverse events. People with high anaesthetic risk are more likely to experience cardiopulmonary complications and adverse events, for example hypercapnia and acidosis, which has to be avoided by hyperventilation...
June 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28624698/brief-mindfulness-training-de-couples-the-anxiogenic-effects-of-distress-intolerance-on-reactivity-to-and-recovery-from-stress-among-deprived-smokers
#8
Rotem Paz, Ariel Zvielli, Pavel Goldstein, Amit Bernstein
OBJECTIVE: We tested whether mindfulness de-couples the expected anxiogenic effects of distress intolerance on psychological and physiological reactivity to and recovery from an anxiogenic stressor among participants experimentally sensitized to experience distress. METHOD: N = 104 daily smokers underwent 18-hours of biochemically-verified smoking deprivation. Participants were then randomized to a 7-min analogue mindfulness intervention (present moment attention and awareness training; PMAA) or a cope-as-usual control condition; and subsequently exposed to a 2...
August 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28619295/effects-of-massage-therapy-on-anxiety-depression-hyperventilation-and-quality-of-life-in-hiv-infected-patients-a-randomized-controlled-trial
#9
RANDOMIZED CONTROLLED TRIAL
Reychler Gregory, Caty Gilles, Arcq Aude, Lebrun Laurie, Belkhir Leïla, Yombi Jean-Cyr, Marot Jean-Christophe
INTRODUCTION: HIV infection is often preceded or accompanied by psychiatric comorbidities. These disorders improve with complementary therapies. The aim of this study was to measure the effect of massage therapy on anxiety, depression, hyperventilation and quality of life in HIV infected patients. METHOD: Adult HIV-infected patients were randomized (n=29) in massage therapy group (one hour a week during four weeks) and control group. Anxiety and depression (HADS-A and HADS-D), hyperventilation (Nijmegen questionnaire) and quality of life (WHOQOL-HIV) were evaluated at inclusion and after 4 weeks...
June 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28614985/stimulation-of-abdominal-and-upper-thoracic-muscles-with-surface-electrodes-for-respiration-and-cough-acute-studies-in-adult-canines
#10
James S Walter, Joseph Posluszny, Raymond Dieter, Robert S Dieter, Scott Sayers, Kiratipath Iamsakul, Christine Staunton, Donald Thomas, Mark Rabbat, Sanjay Singh
OBJECTIVE: To optimize maximal respiratory responses with surface stimulation over abdominal and upper thorax muscles and using a 12-Channel Neuroprosthetic Platform. METHODS: Following instrumentation, six anesthetized adult canines were hyperventilated sufficiently to produce respiratory apnea. Six abdominal tests optimized electrode arrangements and stimulation parameters using bipolar sets of 4.5 cm square electrodes. Tests in the upper thorax optimized electrode locations, and forelimb moment was limited to slight-to-moderate...
June 14, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28608327/diffusional-kurtosis-imaging-dki-incorporation-into-an-intravoxel-incoherent-motion-ivim-mr-model-to-measure-cerebral-hypoperfusion-induced-by-hyperventilation-challenge-in-healthy-subjects
#11
Aude Pavilla, Giulio Gambarota, Alessandro Arrigo, Mehdi Mejdoubi, Régis Duvauferrier, Hervé Saint-Jalmes
OBJECTIVES: The objectives were to investigate the diffusional kurtosis imaging (DKI) incorporation into the intravoxel incoherent motion (IVIM) model for measurements of cerebral hypoperfusion in healthy subjects. MATERIALS AND METHODS: Eight healthy subjects underwent a hyperventilation challenge with a 4-min diffusion weighted imaging protocol, using 8 b values chosen with the Cramer-Rao Lower Bound optimization approach. Four regions of interest in gray matter (GM) were analyzed with the DKI-IVIM model and the bi-exponential IVIM model, for normoventilation and hyperventilation conditions...
June 12, 2017: Magma
https://www.readbyqxmd.com/read/28605206/the-effect-of-a-holistic-self-management-plan-on-asthma-control
#12
Eirini Grammatopoulou, Emmanouil K Skordilis, Aikaterini Haniotou, Zarotis John, Spyros Athanasopoulos
The holistic self-management plan includes lifelong actions that enable patients to cope with their disease. The present study was designed to evaluate the effect of a holistic self-management plan on asthma control. A 12-month controlled study was conducted. Adult patients with mild-to-moderate asthma (n = 24) who attended the emergency asthma department were randomized to two groups: One group followed four educational sessions and three personal home sessions (n = 12), while a second group received a short manual with asthma information (n = 12)...
June 12, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28598405/design-and-validation-of-a-breathing-detection-system-for-scuba-divers
#13
Corentin Altepe, S Murat Egi, Tamer Ozyigit, D Ruzgar Sinoplu, Alessandro Marroni, Paola Pierleoni
Drowning is the major cause of death in self-contained underwater breathing apparatus (SCUBA) diving. This study proposes an embedded system with a live and light-weight algorithm which detects the breathing of divers through the analysis of the intermediate pressure (IP) signal of the SCUBA regulator. A system composed mainly of two pressure sensors and a low-power microcontroller was designed and programmed to record the pressure sensors signals and provide alarms in absence of breathing. An algorithm was developed to analyze the signals and identify inhalation events of the diver...
June 9, 2017: Sensors
https://www.readbyqxmd.com/read/28574856/camera-based-measurement-of-respiratory-rates-is-reliable
#14
Christoph Becker, Stefan Achermann, Mukul Rocque, Ihor Kirenko, Andreas Schlack, Thomas Dreher-Hummel, Thomas Zumbrunn, Roland Bingisser, Christian H Nickel
OBJECTIVES: Respiratory rate (RR) is one of the most important vital signs used to detect whether a patient is in critical condition. It is part of many risk scores and its measurement is essential for triage of patients in emergency departments. It is often not recorded as measurement is cumbersome and time-consuming. We intended to evaluate the accuracy of camera-based measurements as an alternative measurement to the current practice of manual counting. MATERIALS AND METHODS: We monitored the RR of healthy male volunteers with a camera-based prototype application and simultaneously by manual counting and by capnography, which was considered the gold standard...
June 1, 2017: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/28574212/calculation-algorithms-alter-the-breath-by-breath-gas-exchange-values-when-abrupt-changes-in-ventilation-occur
#15
Valentina Cettolo, Maria Pia Francescato
The automatic metabolic units calculate breath-by-breath gas exchange from the expiratory data only, applying an algorithm ('expiration-only' algorithm) that neglects the changes in the lung gas stores. These last are theoretically taken into account by a recently proposed algorithm, based on an alternative view of the respiratory cycle ('alternative respiratory cycle' algorithm). The performance of the two algorithms was investigated where changes in the lung gas stores were induced by abrupt increases in ventilation above the physiological demand...
June 2, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28533756/guinea-pig-oxygen-sensing-and-carotid-body-functional-properties
#16
Elvira Gonzalez-Obeso, Inmaculada Docio, Elena Olea, Angel Cogolludo, Ana Obeso, Asuncion Rocher, Angela Gomez-Niño
Mammals have developed different mechanisms to maintain oxygen supply to cells in response to hypoxia. One of those mechanisms, the carotid body (CB) chemoreceptors, is able to detect physiological hypoxia and generate homeostatic reflex responses, mainly ventilatory and cardiovascular. It has been reported that guinea pigs, originally from the Andes, have a reduced ventilatory response to hypoxia compared to other mammals, implying that CB are not completely functional, which has been related to genetically/epigenetically determined poor hypoxia-driven CB reflex...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28530253/sensitivity-and-specificity-of-vestibular-bedside-examination-in-detecting-viii-cranial-nerve-schwannoma-with-sensorineural-sudden-unilateral-hearing-loss-as-presenting-symptom
#17
L Califano, F Salafia, M G Melillo, S Mazzone
The objectives of this study were to identify signs of vestibular nerve suffering through a bedside vestibular examination protocol in case of sudden sensorineural unilateral hearing loss without spontaneous signs of vestibular impairment and to propose a bed-side vestibular examination based protocol for the focused execution of gadolinium-enhanced magnetic resonance imaging (MRI) only if a vestibular schwannoma is suspected. 96 patients, 52 men, 44 women, mean age 57.73 +/- 12.85 years, suffering from sudden sensorineural unilateral hearing loss, which presented neither vertigo nor spontaneous nystagmus, were enrolled...
May 22, 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28527369/prolonged-epileptiform-eeg-runs-are-associated-with-persistent-seizures-in-juvenile-myoclonic-epilepsy
#18
Vibeke Arntsen, Trond Sand, Marte R Syvertsen, Eylert Brodtkorb
OBJECTIVE: In juvenile myoclonic epilepsy (JME), various EEG characteristics have been suggested as poor prognostic signs, but their significance is unclear. The aim of this study was to assess the influence of EEG variables on seizure and psychosocial outcome after a follow-up exceeding 20 years. METHODS: 396 EEG recordings were available for assessment in 40 patients (42 complete digital, 330 paper segments and 24 written reports only). Mean follow-up was 31 years (range 20-68)...
May 8, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28527012/effect-of-voluntary-hypocapnic-hyperventilation-or-moderate-hypoxia-on-metabolic-and-heart-rate-responses-during-high-intensity-intermittent-exercise
#19
Kohei Dobashi, Naoto Fujii, Kazuhito Watanabe, Bun Tsuji, Yosuke Sasaki, Tomomi Fujimoto, Satoru Tanigawa, Takeshi Nishiyasu
PURPOSE: To investigate the effect of voluntary hypocapnic hyperventilation or moderate hypoxia on metabolic and heart rate responses during high-intensity intermittent exercise. METHODS: Ten males performed three 30-s bouts of high-intensity cycling [Ex1 and Ex2: constant-workload at 80% of the power output in the Wingate anaerobic test (WAnT), Ex3: WAnT] interspaced with 4-min recovery periods under normoxic (Control), hypocapnic or hypoxic (2500 m) conditions...
August 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28512500/the-effect-of-chunghyul-dan-on-hyperventilation-induced-carbon-dioxide-reactivity-of-the-middle-cerebral-artery-in-normal-subjects-a-dose-dependent-study
#20
Chul Jin, Sang-Kwan Moon, Seung-Yeon Cho, Seong-Uk Park, Woo-Sang Jung, Jung-Mi Park, Chang-Nam Ko, Ki-Ho Cho, Seungwon Kwon
Background. This study was conducted to show the prompt effect of chunghyul-dan (CHD) on cerebral hemodynamics in order to provide evidence for its use in stroke prevention. Methods. Hyperventilation-induced CO2 reactivity of the middle cerebral artery was measured in 12 healthy male volunteers (mean age: 26.3 ± 1.1 years) using transcranial Doppler sonography. All subjects were examined before and for 3 hours after administration, with an interval of 1 week between measurements. Results. Compared to baseline, the CO2 reactivity of the middle cerebral artery increased significantly at 2 and 3 hours after the administration of CHD (600 mg and 1200 mg)...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
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