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https://www.readbyqxmd.com/read/28333544/joint-fluid-bone-marrow-edemalike-changes-and-ganglion-cysts-in-the-pediatric-wrist-features-that-may-mimic-pathologic-abnormalities-follow-up-of-a-healthy-cohort
#1
Derk F M Avenarius, Lil-Sofie Ording Müller, Karen Rosendahl
OBJECTIVE: The presence of findings at wrist MRI that may mimic disease is a diagnostic problem. The purpose of this study is to examine the occurrence of bone marrow changes resembling edema, joint fluid, and ganglion cysts over time, in a cohort of healthy children. MATERIALS AND METHODS: Seventy-four of 89 healthy children included in a study of normal MRI findings of the wrists were reexamined after a period of 4 years, using the same 1.5-T MRI technique-namely, a coronal T1-weighted and a T2-weighted fat-saturated sequence...
March 23, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28319008/structure-of-yeast-osbp-related-protein-osh1-reveals-key-determinants-for-lipid-transport-and-protein-targeting-at-the-nucleus-vacuole-junction
#2
Mohammad Kawsar Manik, Huiseon Yang, Junsen Tong, Young Jun Im
Yeast Osh1 belongs to the oxysterol-binding protein (OSBP) family of proteins and contains multiple targeting modules optimized for lipid transport at the nucleus-vacuole junction (NVJ). The key determinants for NVJ targeting and the role of Osh1 at NVJs have remained elusive because of unknown lipid specificities. In this study, we determined the structures of the ankyrin repeat domain (ANK), and OSBP-related domain (ORD) of Osh1, in complex with Nvj1 and ergosterol, respectively. The Osh1 ANK forms a unique bi-lobed structure that recognizes a cytosolic helical segment of Nvj1...
March 10, 2017: Structure
https://www.readbyqxmd.com/read/28317278/species-traits-help-predict-small-mammal-responses-to-habitat-homogenization-by-an-invasive-grass
#3
Joseph P Ceradini, Anna D Chalfoun
Invasive plants can negatively affect native species, however, the strength, direction, and shape of responses may vary depending on the type of habitat alteration and the natural history of native species. To prioritize conservation of vulnerable species, it is therefore critical to effectively predict species' responses to invasive plants, which may be facilitated by a framework based on species' traits. We studied the population and community responses of small mammals and changes in habitat heterogeneity across a gradient of cheatgrass (Bromus tectorum) cover, a widespread invasive plant in North America...
March 20, 2017: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/28301514/apolipoprotein-d-expression-does-not-predict-breast-cancer-recurrence-among-tamoxifen-treated-patients
#4
Daniella Klebaner, Stephen Hamilton-Dutoit, Thomas Ahern, Anatasha Crawford, Thomas Jakobsen, Deirdre P Cronin-Fenton, Per Damkier, Emiel Janssen, Anders Kjaersgaard, Anne Gulbech Ording, Håvard Søiland, Henrik Toft Sørensen, Timothy L Lash, Ylva Hellberg
BACKGROUND: Apolipoprotein D (ApoD) has been proposed as a predictor of breast cancer recurrence among estrogen receptor-positive (ER+), tamoxifen-treated patients. METHODS: We conducted a population-based case-control study nested in a population of 11,251 women aged 35-69 years at diagnosis with Stage I-III breast cancer between 1985 and 2001 on Denmark's Jutland Peninsula and registered with the Danish Breast Cancer Cooperative Group. We identified 541 recurrent or contralateral breast cancers cases among women with ER+ disease treated with tamoxifen for at least 1 year and 300 cases in women with ER- disease never treated with tamoxifen...
2017: PloS One
https://www.readbyqxmd.com/read/28269036/assessment-of-frequency-specific-auditory-steady-state-response-using-amplitude-modulation-with-2-order-exponential-envelope
#5
Pablo Cevallos-Larrea, Thobias Pereira, Wagner Santos, Silvana M Frota, Antonio F Infantosi, Roberto M Ichinose, Carlos Tierra-Criollo
This study investigated the performance of Frequency Specific Auditory Steady-State Response (FS-ASSR) detection elicited by the amplitude modulated tone with 2-order exponential envelope (AM2), using objective response detection (ORD) techniques of Spectral F-Test (SFT) and Magnitude Squared Coherence (MSC). ASSRs from 24 normal hearing adults were obtained during binaural multi-tone stimulation of amplitude-modulation (AM) and AM2 at intensities of 60, 45 and 30 dBSPL. The carrier frequencies were 500, 1000, 2000, and 4000 Hz, modulated between 77 and 105 Hz...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28248970/an-eocene-orthocone-from-antarctica-shows-convergent-evolution-of-internally-shelled-cephalopods
#6
Larisa A Doguzhaeva, Stefan Bengtson, Marcelo A Reguero, Thomas Mörs
BACKGROUND: The Subclass Coleoidea (Class Cephalopoda) accommodates the diverse present-day internally shelled cephalopod mollusks (Spirula, Sepia and octopuses, squids, Vampyroteuthis) and also extinct internally shelled cephalopods. Recent Spirula represents a unique coleoid retaining shell structures, a narrow marginal siphuncle and globular protoconch that signify the ancestry of the subclass Coleoidea from the Paleozoic subclass Bactritoidea. This hypothesis has been recently supported by newly recorded diverse bactritoid-like coleoids from the Carboniferous of the USA, but prior to this study no fossil cephalopod indicative of an endochochleate branch with an origin independent from subclass Bactritoidea has been reported...
2017: PloS One
https://www.readbyqxmd.com/read/28241520/optical-rotatory-dispersion-measurement-approach-using-the-nonlinear-behavior-of-the-geometric-phase
#7
Makoto Ginya, Makoto Kimura, Tetsuo Iwata
We propose a method for high-sensitivity optical rotatory dispersion (ORD) measurement of optically active samples that takes advantage of the nonlinear behavior of the geometric phase (GP). To measure the GP as a function of wavelength, we use a multichannel Fourier transform spectrometer (MC-FTS) that is based on Savart plate birefringent-polarization interference, into which we newly insert a zeroth-order quarter-wave plate (QWP). The modified MC-FTS allows us to measure the wavelength dependence of the GP and thus that of the optical rotation angle due to the sample...
February 20, 2017: Optics Express
https://www.readbyqxmd.com/read/28227250/assessment-of-frequency-specific-auditory-steady-state-response-using-amplitude-modulation-with-2-order-exponential-envelope
#8
Pablo Cevallos-Larrea, Thobias Pereira, Wagner Santos, Silvana M Frota, Antonio F Infantosi, Roberto M Ichinose, Carlos Tierra-Criollo, Pablo Cevallos-Larrea, Thobias Pereira, Wagner Santos, Silvana M Frota, Antonio F Infantosi, Roberto M Ichinose, Carlos Tierra-Criollo, Pablo Cevallos-Larrea, Wagner Santos, Silvana M Frota, Carlos Tierra-Criollo, Antonio F Infantosi, Thobias Pereira, Roberto M Ichinose
This study investigated the performance of Frequency Specific Auditory Steady-State Response (FS-ASSR) detection elicited by the amplitude modulated tone with 2-order exponential envelope (AM(2)), using objective response detection (ORD) techniques of Spectral F-Test (SFT) and Magnitude Squared Coherence (MSC). ASSRs from 24 normal hearing adults were obtained during binaural multi-tone stimulation of amplitude-modulation (AM) and AM(2) at intensities of 60, 45 and 30 dBSPL. The carrier frequencies were 500, 1000, 2000, and 4000 Hz, modulated between 77 and 105 Hz...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225789/non-melanoma-skin-cancer-and-risk-of-alzheimer-s-disease-and-all-cause-dementia
#9
Sigrun A J Schmidt, Anne G Ording, Erzsébet Horváth-Puhó, Henrik T Sørensen, Victor W Henderson
Cancer patients may be at decreased risk of Alzheimer's disease. This hypothesis is best developed for non-melanoma skin cancer (NMSC), but supportive epidemiological data are sparse. We therefore conducted a nationwide cohort study of the association between NMSC and Alzheimer's disease (main outcome) and all-cause dementia. Using Danish medical databases, we identified adults diagnosed with NMSC between 1 January 1980 and 30 November 2013 (n = 216,221) and a comparison cohort of five individuals matched to each NMSC patient by sex and birth year (n = 1,081,097)...
2017: PloS One
https://www.readbyqxmd.com/read/28182726/spatial-patterns-of-multidrug-resistant-tuberculosis-and-relationships-to-socio-economic-demographic-and-household-factors-in-northwest-ethiopia
#10
Kefyalew Addis Alene, Kerri Viney, Emma S McBryde, Archie C A Clements
BACKGROUND: Understanding the geographical distribution of multidrug-resistant tuberculosis (MDR-TB) in high TB burden countries such as Ethiopia is crucial for effective control of TB epidemics in these countries, and thus globally. We present the first spatial analysis of multidrug resistant tuberculosis, and its relationship to socio-economic, demographic and household factors in northwest Ethiopia. METHODS: An ecological study was conducted using data on patients diagnosed with MDR-TB at the University of Gondar Hospital MDR-TB treatment centre, for the period 2010 to 2015...
2017: PloS One
https://www.readbyqxmd.com/read/28179410/gliding-lizards-use-the-position-of-the-sun-to-enhance-social-display
#11
Danielle A Klomp, Devi Stuart-Fox, Indraneil Das, Terry J Ord
Effective communication requires animal signals to be readily detected by receivers in the environments in which they are typically given. Certain light conditions enhance the visibility of colour signals and these conditions can vary depending on the orientation of the sun and the position of the signaller. We tested whether Draco sumatranus gliding lizards modified their position relative to the sun to enhance the conspicuousness of their throat-fan (dewlap) during social display to conspecifics. The dewlap was translucent, and we found that lizards were significantly more likely to orient themselves perpendicular to the sun when displaying...
February 2017: Biology Letters
https://www.readbyqxmd.com/read/28139956/bacterial-microbiota-in-harbor-seals-phoca-vitulina-from-the-north-sea-of-schleswig-holstein-germany-around-the-time-of-morbillivirus-and-influenza-epidemics
#12
Ursula Siebert, Marion Rademaker, Sophie A Ulrich, Peter Wohlsein, Katrin Ronnenberg, Ellen Prenger-Berninghoff
We present microbiologic findings in harbor seal (phoca; Phoca vitulina ) carcasses collected from the North Sea of Schleswig-Holstein, Germany, 1996-2014, and interpret results in relation to potential variations caused by phocine distemper virus and influenza A virus mass mortalities. We conducted microbiologic investigations on 2,124 tissue samples from lung, liver, kidney, spleen, intestine, and mesenteric lymph nodes from 549 dead harbor seals of the German North Sea. A large variety of bacteria, including potentially pathogenic species such as Bordetella bronchiseptica , Brucella spp...
January 31, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28126318/exploring-spatial-autocorrelation-of-traffic-crashes-based-on-severity
#13
Ali Soltani, Sajad Askari
As a developing country, Iran has one of the highest crash-related deaths, with a typical rate of 15.6 cases in every 100 thousand people. This paper is aimed to find the potential temporal and spatial patterns of road crashes aggregated at traffic analysis zonal (TAZ) level in urban environments. Localization pattern and hotspot distribution were examined using geo-information approach to find out the impact of spatial/temporal dimensions on the emergence of such patterns. The spatial clustering of crashes and hotspots were assessed using spatial autocorrelation methods such as the Moran's I and Getis-Ord Gi* index...
January 19, 2017: Injury
https://www.readbyqxmd.com/read/28121050/imaging-in-pediatric-renal-transplantation
#14
REVIEW
Maria Beatrice Damasio, Lil-Sofie Ording Muller, Giorgio Piaggio, Stephen D Marks, Michael Riccabona
Renal transplantation is the therapy of choice in children with ESKD. Radiological investigations are required in both pre- and post-transplant assessment, although there is paucity of both consensus-based statements and evidence-based imaging guidelines in pediatric renal transplantation. The phases of pediatric ESKD management that require imaging are pretransplantation recipient assessment and post-transplantation surveillance for detection of potential complications. We present suggestions for imaging algorithms for both pre- and post-transplant assessment in pediatric renal transplant recipients...
January 25, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28118957/the-role-of-chirality-in-a-set-of-key-intermediates-of-pharmaceutical-interest-3-aryl-substituted-%C3%AE-butyrolactones-evidenced-by-chiral-hplc-separation-and-by-chiroptical-spectroscopies
#15
Daniela Rossi, Rita Nasti, Simona Collina, Giuseppe Mazzeo, Simone Ghidinelli, Giovanna Longhi, Maurizio Memo, Sergio Abbate
The enantiomers of four chiral 3-aryl-substituted-γ-butyrolactones, key intermediates for the preparation of compounds of pharmaceutical interest, were successfully isolated by enantioselective chromatography, employing the Chiralpak AD-H chiral stationary phase. For all compounds the same elution order was observed, as monitored by a full set of chiroptical methods that we employed, namely ORD (optical rotatory dispersion), ECD (electronic circular dichroism, or CD in the UV range), and VCD (vibrational circular dichroism, or CD in the IR range)...
January 5, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28090255/clinical-utility-of-echocardiography-for-the-diagnosis-and-prognosis-in-children-with-bronchopulmonary-dsyplasia
#16
Young Earl Choi, Hwa Jin Cho, Eun Song Song, In Seok Jeong, Namsik Yoon, Young Youn Choi, Jae Sook Ma, Young Kuk Cho
BACKGROUND: Bronchopulmonary dysplasia (BPD) may result in chronic pulmonary artery hypertension and right ventricular (RV) dysfunction. Various echocardiographic assessments of RV dysfunction have been used to determine whether echocardiographic measurements of premature infants with BPD could provide sensitive measures of RV function that correlates with BPD severity. METHODS: Twenty-eight control subjects without BPD (non BPD group), 28 patients with mild BPD, 11 patients with moderate BPD, and six patients with severe BPD underwent echocardiograms with standard measurement such as ejection fraction by M-mode, tricuspid regurgitation pressure gradient, myocardial performance index (MPI) derived from pulse Doppler, and tissue Doppler imaging (TDI) measurements...
December 2016: Journal of Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28088242/differences-in-spatial-distributions-of-iron-supplementation-use-among-pregnant-women-and-associated-factors-in-ethiopia-evidence-from-the-2011-national-population-based-survey
#17
Demewoz Haile, Lianna Tabar, Yihunie Lakew
BACKGROUND: Iron supplementation during pregnancy prevents against low birth weight, incidence of prematurity and postpartum hemorrhage. However, the coverage of iron supplementation is still low in Ethiopia. This study aimed to investigate the spatial variations and associated factors of iron supplementation during pregnancy using the 2011 national demographic and health survey data. METHODS: This study used secondary data from the 2011 Ethiopian demographic and health survey...
January 14, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28057140/-spatial-analysis-and-prediction-of-severe-fever-with-thrombocytopenia-syndrome-in-zhejiang-province-2011-2015
#18
H C Wu, X P Xu, C Wu, Q B Lu, Z Y Ding, J F Lin
Objective: To understand the distribution of the severe fever with thrombocytopenia syndrome (SFTS) in Zhejiang province, and predict the incidence and the probability of SFTS outbreak. Methods: Based on the cases of SFTS from 2011-2015, software ArcGIS 10.0 was used to analyze the spatial distribution, Moran's I and Getis-Ord Gi were used to analyze the spatial autocorrelation. The incidence trend was explored by trend surface analysis, and the prediction was made by Kriging interpolation. Results: The incidence of SFTS increased and the distribution expanded in Zhejiang from 2011 to 2015, the seasonal and the demographic characteristics of SFTS were similar to the previous research; there were regional clustering of the cases (P<0...
November 10, 2016: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28042980/extensive-regional-metastasis-of-high-grade-mucoepidermoid-carcinoma-of-an-unknown-primary%C3%A2-tumor
#19
Naseem Ghazali, Alyssa Flashburg, Robert A Ord
PURPOSE: Mucoepidermoid carcinoma (MEC) is the most common salivary carcinoma. It arises most frequently in the major salivary glands, but can also arise in minor glands or intraosseous sites. MEC of an unknown primary occurs very rarely. The present report documents only the third case reported in medical studies. METHODS: A 66-year-old man with previous carcinoma in situ (CIS) of the left posterior oral tongue that had been excised in 2004 and again in 2010 presented with a hard lymph node, 3 × 2 cm at level II of the right neck in July 2015...
December 15, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28019106/geographic-distributions-of-motor-neuron-disease-mortality-and-well-water-use-in-u-s-counties
#20
Gary G Schwartz, Bradley C Rundquist, Isaac J Simon, Sami E Swartz
OBJECTIVE: We recently reported that U.S. mortality rates for motor neuron disease (MND) at the level of the state are associated with well water use. However, data at the state level may not accurately reflect data at the individual level. We therefore examined the association between MND mortality and well water use utilizing data from smaller geographic units that may better reflect exposure and disease at the individual level. METHODS: We used data on age-adjusted MND mortality rates at the level of the county, obtained from the CDC, and corresponding data on the prevalence of well water use, obtained from the U...
December 25, 2016: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
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