keyword
MENU ▼
Read by QxMD icon Read
search

Ord

keyword
https://www.readbyqxmd.com/read/28926691/cobalt-porphyrin-thiazyl-radical-coordination-polymers-towards-metal-organic-electronics
#1
Delia A Haynes, Laura J van Laeren, Orde Q Munro
Herein we delineate an unusual one-dimensional coordination polymer (CP), 3, prepared from S = ½ Co(TPP), 1, (TPP = 5,10,15,20-tetraphenylporphyrin dianion) and S = ½ 4-(4'-pyridyl)-1,2,3,5-dithiadiazolyl (py-DTDA) radical, 2. The atypically long S-S distance for CP 3 (2.12 Å) reflects fractional electron transfer from the formally Co(II) ion into the antibonding π-SOMO of the metal-bound py-DTDA bridging ligand. The bonding in solid CP 3 involves non-integer redox states in a resonance hybrid repeat unit best formulated as [Co(TPP)](0...
September 19, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28901768/importance-and-difficulties-in-the-use-of-chiroptical-methods-to-assign-the-absolute-configuration-of-natural-products-the-case-of-phytotoxic-pyrones-and-furanones-produced-by-diplodia-corticola
#2
Giuseppe Mazzeo, Alessio Cimmino, Marco Masi, Giovanna Longhi, Lucia Maddau, Maurizio Memo, Antonio Evidente, Sergio Abbate
α-Pyrones and furanones are metabolites produced by Diplodia corticola, a pathogen of cork oak. Previously, the absolute configuration (AC) of diplopyrone was defined by chiroptical methods and Mosher's method. Using X-ray and chiroptical methods, the AC of sapinofuranone C was assigned, while that of the (4S,5S)-enantiomer of sapinofuranone B was established by enantioselective total synthesis. Diplofuranone A and diplobifuranylones A-C ACs are still unassigned. Here electronic and vibrational circular dichroism (ECD and VCD) and optical rotatory dispersion (ORD) spectra are reported and compared with density functional theory computations...
September 13, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28878692/optimization-of-an-in-silico-cardiac-cell-model-for-proarrhythmia-risk-assessment
#3
Sara Dutta, Kelly C Chang, Kylie A Beattie, Jiansong Sheng, Phu N Tran, Wendy W Wu, Min Wu, David G Strauss, Thomas Colatsky, Zhihua Li
Drug-induced Torsade-de-Pointes (TdP) has been responsible for the withdrawal of many drugs from the market and is therefore of major concern to global regulatory agencies and the pharmaceutical industry. The Comprehensive in vitro Proarrhythmia Assay (CiPA) was proposed to improve prediction of TdP risk, using in silico models and in vitro multi-channel pharmacology data as integral parts of this initiative. Previously, we reported that combining dynamic interactions between drugs and the rapid delayed rectifier potassium current (IKr) with multi-channel pharmacology is important for TdP risk classification, and we modified the original O'Hara Rudy ventricular cell mathematical model to include a Markov model of IKr to represent dynamic drug-IKr interactions (IKr-dynamic ORd model)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28864988/long-term-effects-of-the-periconception-period-on-embryo-epigenetic-profile-and-phenotype-the-role-of-stress-and-how-this-effect-is-mediated
#4
James Ord, Alireza Fazeli, Penelope J Watt
Stress represents an unavoidable aspect of human life, and pathologies associated with dysregulation of stress mechanisms - particularly psychiatric disorders - represent a significant global health problem. While it has long been observed that levels of stress experienced in the periconception period may greatly affect the offspring's risk of psychiatric disorders, the mechanisms underlying these associations are not yet comprehensively understood. In order to address this question, this chapter will take a 'top-down' approach, by first defining stress and associated concepts, before exploring the mechanistic basis of the stress response in the form of the hypothalamic-pituitary-adrenal (HPA) axis, and how dysregulation of the HPA axis can impede our mental and physical health, primarily via imbalances in glucocorticoids (GCs) and their corresponding receptors (GRs) in the brain...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28859279/the-superovulated-environment-independent-of-embryo-vitrification-results-in-low-birthweight-in-a-mouse-model
#5
Rachel Weinerman, Teri Ord, Marisa S Bartolomei, Christos Coutifaris, Monica Mainigi
Epidemiological studies suggest that babies born following in vitro fertilization (IVF) and fresh embryo transfer are of lower birthweight than babies born following frozen embryo transfer, although the mechanism responsible for this phenotype is not known. We developed a novel mouse model that isolates the independent effects of embryo freezing and the superovulated environment, which cannot be performed in humans. We transferred blastocysts that had been vitrified and warmed, mixed with with fresh blastocysts, into individual pseudopregnant recipients produced by either natural mating or mating following injection with equine chorionic gonadotropin and human chorionic gonadotropin and hCG (superovulation)...
July 1, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28857472/dual-ph-magnetic-field-controlled-drug-delivery-systems-based-on-fe3-o4-sio2-incorporated-salecan-graft-copolymer-composite-hydrogels
#6
Xinyu Hu, Yongmei Wang, Liangliang Zhang, Man Xu, Jianfa Zhang, Wei Dong
Salecan is a water-soluble extracellular β-glucan and has excellent physicochemical and biological properties for hydrogel preparation. In this study, a new pH/magnetic field dual-responsive hydrogel was prepared by the graft copolymerization of salecan with 4-pentenoic acid (PA) and N-hydroxyethylacrylamide (HEAA) in the presence of Fe3 O4 @SiO2 nanoparticles for doxorubicin hydrochloride (DOX) release. Integration of Fe3 O4 @SiO2 nanoparticles in salecan-g-poly(PA-co-HEAA) copolymers afforded magnetic sensitivity to the original material...
August 31, 2017: ChemMedChem
https://www.readbyqxmd.com/read/28852767/european-society-of-paediatric-radiology-abdominal-imaging-task-force-recommendations-in-paediatric-uroradiology-part-ix-imaging-in-anorectal-and-cloacal-malformation-imaging-in-childhood-ovarian-torsion-and-efforts-in-standardising-paediatric-uroradiology
#7
REVIEW
Michael Riccabona, Maria-Luisa Lobo, Lil-Sofie Ording-Muller, A Thomas Augdal, E Fred Avni, Johan Blickman, Constanza Bruno, Beatrice Damasio, Kassa Darge, Akaterina Ntoulia, Frederica Papadopoulou, Pierre-Hugues Vivier
At the occasion of the European Society of Paediatric Radiology (ESPR) annual meeting 2015 in Graz, Austria, the newly termed ESPR abdominal (gastrointestinal and genitourinary) imaging task force set out to complete the suggestions for paediatric urogenital imaging and procedural recommendations. Some of the last missing topics were addressed and proposals on imaging of children with anorectal and cloacal malformations and suspected ovarian torsion were issued after intense discussions and a consensus finding process that considered all evidence...
September 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28833487/absolute-configuration-of-an-axially-chiral-sulfonate-determined-from-its-optical-rotatory-dispersion-electronic-circular-dichroism-and-vibrational-circular-dichroism-spectra
#8
Cody L Covington, Vijay Raghavan, Jonathan P Smuts, Daniel W Armstrong, Prasad L Polavarapu
The absolute configuration (AC) of an axially chiral sulfonate (aCSO), 3,5-dimethyl-2-(naphthalen-1-yl)-6-(naphthalen-1-yl)benzenesulfonate (labeled as aCSO5), was investigated using optical rotatory dispersion (ORD), electronic circular dichroism (ECD), and vibrational circular dichroism (VCD) spectroscopies. All three methods led to the same conclusion and the AC of aCSO5 is reliably determined to be (-)-(aR, aR), or conversely (+)-(aS, aS).
August 18, 2017: Chirality
https://www.readbyqxmd.com/read/28830521/addressing-geographic-access-barriers-to-emergency-care-services-a-national-ecologic-study-of-hospitals-in-brazil
#9
Thiago Augusto Hernandes Rocha, Núbia Cristina da Silva, Pedro Vasconcelos Amaral, Allan Claudius Queiroz Barbosa, João Victor Muniz Rocha, Viviane Alvares, Dante Grapiuna de Almeida, Elaine Thumé, Erika Bárbara Abreu Fonseca Thomaz, Rejane Christine de Sousa Queiroz, Marta Rovery de Souza, Adriana Lein, Daniel Paulino Lopes, Catherine A Staton, João Ricardo Nickenig Vissoci, Luiz Augusto Facchini
BACKGROUND: Unequal distribution of emergency care services is a critical barrier to be overcome to assure access to emergency and surgical care. Considering this context it was objective of the present work analyze geographic access barriers to emergency care services in Brazil. A secondary aim of the study is to define possible roles to be assumed by small hospitals in the Brazilian healthcare network to overcome geographic access challenges. METHODS: The present work can be classified as a cross-sectional ecological study...
August 22, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28821371/at-the-intersection-of-place-race-and-health-in-brazil-residential-segregation-and-cardio-metabolic-risk-factors-in-the-brazilian-longitudinal-study-of-adult-health-elsa-brasil
#10
Sharrelle Barber, Ana V Diez Roux, Letícia Cardoso, Simone Santos, Veronica Toste, Sherman James, Sandhi Barreto, Maria Schmidt, Luana Giatti, Dora Chor
Residential segregation is the spatial manifestation of entrenched socioeconomic and racial inequities and is considered a fundamental cause of racial inequalities in health. Despite the well-documented racialized spatial inequalities that exist in urban areas throughout Brazil, few empirical investigations have examined the link between residential segregation and health and considered its implications for racial health inequalities in this setting. In the present study, we used data from the Brazilian Longitudinal Study of Adult Health (2008-2010) to examine the association between economic residential segregation and two major cardio-metabolic risk factors-hypertension and diabetes...
May 27, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28811885/manipulation-of-habitat-isolation-and-area-implicates-deterministic-factors-and-limited-neutrality-in-community-assembly
#11
Terry J Ord, Jack Emblen, Mattias Hagman, Ryan Shofner, Sara Unruh
Theory predicts deterministic and stochastic factors will contribute to community assembly in different ways: Environmental filters should regulate those species that establish in a particular area resulting in the ecological requirements of species being the primary driver of species distributions, while chance and dispersal limitation should dictate the likelihood of species reaching certain areas with the ecology of species being largely neutral. These factors are specifically relevant for understanding how the area and isolation of different habitats or islands interact to affect community composition...
August 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28796664/interaction-of-health-care-worker-health-and-safety-and-patient-health-and-safety-in-the-us-health-care-system-recommendations-from-the-2016-summit
#12
Ronald Loeppke, Jodie Boldrighini, John Bowe, Barbara Braun, Erik Eggins, Barry S Eisenberg, Paul Grundy, Todd Hohn, T Warner Hudson, John Kannas, E Andrew Kapp, Doris Konicki, Paul Larson, Stephanie McCutcheon, Robert K McLellan, Julie Ording, Charlotte Perkins, Mark Russi, Cindy Stutts, Mary Yarbrough
No abstract text is available yet for this article.
August 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28771119/silvanigrella-aquatica-gen-nov-sp-nov-isolated-from-a-freshwater-lake-description-of-silvanigrellaceae-fam-nov-and-silvanigrellales-ord-nov-reclassification-of-the-order-bdellovibrionales-in-the-class-oligoflexia-reclassification-of-the-families-bacteriovoracaceae
#13
Martin W Hahn, Johanna Schmidt, Ulrike Koll, Manfred Rohde, Susanne Verbarg, Alexandra Pitt, Ryosuke Nakai, Takeshi Naganuma, Elke Lang
The unusual chemo-organoheterotrophic proteobacterial strain MWH-Nonnen-W8redT was isolated from a lake located in the Black Forest (Schwarzwald), Germany, by using the filtration-acclimatization method. Phylogenetic analyses based on the 16S rRNA gene sequence of the strain could not provide clear hints on classification of the strain in one of the current classes of the phylum Proteobacteria. Whole-genome sequencing resulted in a genome size of 3.5 Mbp and revealed a quite low DNA G+C content of 32.6 mol%...
August 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28769677/a-review-of-the-flea-genus-phalacropsylla-rothschild-1915-siphonaptera-ctenophthalmidae-neopsyllinae-phalacropsyllini-with-new-host-and-distributional-records
#14
Roxana Acosta, Michael W Hastriter
A redescription of the genus Phalacropsylla Rothschild is provided. Six species are recognized: Phalacropsylla allos Wagner, P. hamata Tipton and Mendez, P. morlani Eads and Campos, P. nivalis Barrera and Traub, P. oregonensis Lewis and Maser, and P. paradisea Rothschild. Phalacropsylla hamata is designated herein as a junior synonym of P. paradisea. The distribution of P. paradisea is more extensive than previously thought, extending from Arizona through southern Colorado, into New Mexico, Texas, and northern Mexico (State of Nuevo León)...
2017: ZooKeys
https://www.readbyqxmd.com/read/28758193/melanopsin-ganglion-cell-outer-retinal-dendrites-morphologically-distinct-and-asymmetrically-distributed-in-the-mouse-retina
#15
Katelyn B Sondereker, Jessica R Onyak, Shakib W Islam, Christopher L Ross, Jordan M Renna
A small population of retinal ganglion cells express the photopigment melanopsin and function as autonomous photoreceptors. They encode global luminance levels critical for light-mediated non-image forming visual processes including circadian rhythms and the pupillary light reflex. There are five melanopsin ganglion cell subtypes (M1-M5). M1 and displaced M1 (M1d) cells have dendrites that ramify within the outermost layer of the inner plexiform layer (IPL). It was recently discovered that some melanopsin ganglion cells extend dendrites into the outer retina...
July 31, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28753971/spatio-temporal-variation-of-longevity-clusters-and-the-influence-of-social-development-level-on-lifespan-in-a-chinese-longevous-area-1982-2010
#16
Jian Qin, Guoqi Yu, Tianlong Xia, You Li, Xue Liang, Peng Wei, Bingshuang Long, Mingzhi Lei, Xiao Wei, Xianyan Tang, Zhiyong Zhang
The study aims to determine the spatial and temporal variation of a longevous region and explore the correlation between longevity and socioeconomic development. Population data at the township level were obtained from the last four population censuses (1982-2010). Five main lifespan indicators and the Human Development Index (HDI) were calculated. Getis-Ord G*, Gravity modeling, and Pearson's r between lifespan indicators and HDI were applied. In this study, a stable longevous gathering area was discovered in Hechi during different periods...
July 19, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28751721/evidence-for-a-role-of-trib3-in-the-regulation-of-megakaryocytopoiesis
#17
Lee Butcher, Maninder Ahluwalia, Tiit Örd, Jessica Johnston, Roger H Morris, Endre Kiss-Toth, Tõnis Örd, Jorge D Erusalimsky
Megakaryocytopoiesis is a complex differentiation process driven by the hormone thrombopoietin by which haematopoietic progenitor cells give rise to megakaryocytes, the giant bone marrow cells that in turn break down to form blood platelets. The Tribbles Pseudokinase 3 gene (TRIB3) encodes a pleiotropic protein increasingly implicated in the regulation of cellular differentiation programmes. Previous studies have hinted that TRIB3 could be also involved in megakaryocytopoiesis but its role in this process has so far not been investigated...
July 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28747815/identification-of-very-small-open-reading-frames-in-the-genomes-of-holmes-jungle-virus-ord-river-virus-and-wongabel-virus-of-the-genus-hapavirus-family-rhabdoviridae
#18
REVIEW
Aneta Gubala, Susan Walsh, Jane McAllister, Richard Weir, Steven Davis, Lorna Melville, Ian Mitchell, Dieter Bulach, Penny Gauci, Alex Skvortsov, David Boyle
Viruses of the family Rhabdoviridae infect a broad range of hosts from a variety of ecological and geographical niches, including vertebrates, arthropods, and plants. The arthropod-transmitted members of this family display considerable genetic diversity and remarkable genomic flexibility that enable coding for various accessory proteins in different locations of the genome. Here, we describe the genome of Holmes Jungle virus, isolated from Culex annulirostris mosquitoes collected in northern Australia, and make detailed comparisons with the closely related Ord River and Wongabel viruses, with a focus on identifying very small open reading frames (smORFs) in their genomes...
2017: Evolutionary Bioinformatics Online
https://www.readbyqxmd.com/read/28738782/space-and-space-time-distributions-of-dengue-in-a-hyper-endemic-urban-space-the-case-of-girardot-colombia
#19
Mauricio Fuentes-Vallejo
BACKGROUND: Dengue is a widely spread vector-borne disease. Dengue cases in the Americas have increased over the last few decades, affecting various urban spaces throughout these continents, including the tourism-oriented city of Girardot, Colombia. Interactions among mosquitoes, pathogens and humans have recently been examined using different temporal and spatial scales in attempts to determine the roles that social and ecological systems play in dengue transmission. The current work characterizes the spatial and temporal behaviours of dengue in Girardot and discusses the potential territorial dynamics related to the distribution of this disease...
July 24, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28715359/attempting-to-validate-the-over-under-triage-matrix-at-a-level-i-trauma-center
#20
James W Davis, Rachel C Dirks, Lawrence P Sue, Krista L Kaups
BACKGROUND: The Optimal Resources Document (ORD) mandates trauma activation based on injury mechanism, physiologic and anatomic criteria and recommends using the over/undertriage matrix (Matrix) to evaluate the appropriateness of trauma team activation. The purpose of this study was to assess the effectiveness of the Matrix method by comparing patients appropriately triaged with those undertriaged. We hypothesized that these two groups are different and Matrix does not discriminate the needs or outcomes of these different groups of patients...
July 15, 2017: Journal of Trauma and Acute Care Surgery
keyword
keyword
27710
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"