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Pingping Ren, Fei Han, Liangliang Chen, Yu Xu, Ying Wang, Jianghua Chen
BACKGROUND: Henoch-Schönlein purpura (HSP) is a form of systemic vasculitis that can progress to Henoch-Schönlein purpura nephritis (HSPN), and the most effective treatment remains controversial. Our aim was to compare the effects of oral mycophenolate mofetil (MMF) with low-dose prednisone and the full-dose corticosteroids (CS; prednisone) for the induction therapy of HSPN with large proteinuria. METHODS: Fifty-three patients with biopsy-proved HSPN with large proteinuria (>2...
2012: American Journal of Nephrology
Yue Du, Ling Hou, Chengguang Zhao, Mei Han, Yubin Wu
BACKGROUND: Henoch-Schönlein purpura (HSP) can progress to Henoch-Schönlein purpura nephritis (HSPN), and the most effective management remains unclear. Our aim was to evaluate the efficacy of mycophenolate mofetil (MMF) for treating pediatric patients with HSPN and nephrotic-range proteinuria. METHODS: Twelve children, seven boys and five girls, mean age 8.33 (range 6-12) years at the time of HSPN diagnosis with nephrotic-range proteinuria, were treated with MMF...
May 2012: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
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