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Colorectal cancer surgery

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https://www.readbyqxmd.com/read/29235512/a-multimodal-biomicroscopic-system-based-on-high-frequency-acoustic-radiation-force-impulse-and-multispectral-imaging-techniques-for-tumor-characterization-ex-vivo
#1
Jihun Kim, Anna Seo, Jun-Young Kim, Sung Hyouk Choi, Hyung-Jin Yoon, Eunjoo Kim, Jae Youn Hwang
We report a multimodal biomicroscopic system which offers high-frequency ultrasound B-mode, acoustic radiation force impulse (ARFI), and multispectral imaging for qualitative tumor characterization ex vivo. Examinations of resected tissues from diseased regions such as tumors are crucial procedures during surgical operations to treat cancer. Particularly, if tiny tumors remain at surgical sites after tumor resection, such tumors can result in unwanted outcomes, such as cancer recurrence or metastasis to other organs...
December 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29234938/impact-of-incisional-hernia-development-following-abdominal-operations-on-total-healthcare-cost
#2
Vamsi V Alli, Jianying Zhang, Dana A Telem
BACKGROUND: Introduction of the category III CPT code (0437T) for prophylactic mesh augmentation (PMA) highlights efforts to reduce incisional hernia (IH). PMA's value in the context of value-based care requires understanding both the cost of IH development and the savings from prevention. We hypothesized large healthcare costs with IH development. Appreciating which subsets of patients are at highest risk for IH, and the subsets who have the costliest care is essential in targeting interventions for hernia prevention...
December 12, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29233580/colorectal-carcinoma-in-the-frail-surgical-patient-implementation-of-a-work-area-focused-on-the-complex-surgical-patient-improves-postoperative-outcome
#3
Jordi Castellví Valls, Núria Borrell Brau, María José Bernat, Patricia Iglesias, Lluís Reig, Lluís Pascual, Marina Vendrell, Pilar Santos, Lorenzo Viso, Núria Farreres, Gonzalo Galofre, Carmen Deiros, Pedro Barrios
INTRODUCTION: Advanced age and comorbidity impact on post-operative morbi-mortality in the frail surgical patient. The aim of this study is to assess the impact of a comprehensive, multidisciplinary and individualized care delivered to the frail patient by implementation of a Work Area focused on the Complex Surgical Patient (CSPA). METHODS: Retrospective study with prospective data collection. Ninety one consecutive patients, classified as frail (ASAIII or IV, Barthel<80 and/or Pfeiffer>3) underwent curative radical surgery for colorectal carcinoma between 2013 and 2015...
December 9, 2017: Cirugía Española
https://www.readbyqxmd.com/read/29233486/cetuximab-combined-with-induction-oxaliplatin-and-capecitabine-followed-by-neoadjuvant-chemoradiation-for-locally-advanced-rectal-cancer-swog-0713
#4
Cynthia Gail Leichman, Shannon L McDonough, Stephen R Smalley, Kevin G Billingsley, Heinz-Josef Lenz, Matthew A Beldner, Aram F Hezel, Mario R Velasco, Katherine A Guthrie, Charles D Blanke, Howard S Hochster
BACKGROUND: Neoadjuvant chemoradiation (NCRT) is standard treatment for locally advanced rectal cancer. Pathologic complete response (pCR) has associated with improved survival. In modern phase III trials of NCRT, pCR ranges from 10% to 20%. Cetuximab improves response in KRAS (KRAS proto-oncogene) wild type (wt) metastatic colorectal cancer. S0713 was designed to assess improvement in pCR with additional use of cetuximab with induction chemotherapy and NCRT for locally advanced, KRAS-wt rectal cancer...
October 24, 2017: Clinical Colorectal Cancer
https://www.readbyqxmd.com/read/29233454/does-radiotherapy-prior-to-surgery-improve-long-term-prognosis-in-pediatric-colorectal-cancer-in-lower-and-upper-middle-income-countries-with-limited-resources-our-experience-and-literature-review
#5
Yacoob Omar Carrim, Luvo Gaxa, Francisca van der Schyff, Nndweleni Meshack Bida, Fareed Omar, Zarina Lockhat
Colorectal carcinoma in children and adolescents is extremely rare, with an annual incidence <0.3 cases per million, most frequently reported in the second decade of life. It accounts for severe morbidity and poor prognosis owing to the low index of suspicion, delayed diagnosis, advanced stage at presentation and the aggressive tumor nature. Patients present with abdominal pain, vomiting, constipation, abdominal distension, rectal tenesmus, iron-deficiency anemia, change in bowel habit and weight loss...
December 7, 2017: Journal of the Egyptian National Cancer Institute
https://www.readbyqxmd.com/read/29232533/laparoscopic-abdominal-transanal-proctocolectomy-with-coloanal-anastomosis-is-a-good-surgical-option-in-selective-patients-with-low-lying-rectal-cancer-a-retrospective-analysis-based-on-a-single-surgeon-s-experience
#6
Bong-Hyeon Kye, Jun-Gi Kim, Hyeon-Min Cho, Hyung-Jin Kim, Chung-Soo Chun
PURPOSE: We intended to identify the oncological outcome for rectal cancer over the past 20 years and whether or not sphincter-preserving surgery is an appropriate approach for low-lying rectal cancer. MATERIALS AND METHODS: The oncological outcomes from a total of 418 patients who electively underwent rectal cancer surgery for a lesion located within 8 cm of the anal verge by a single colorectal surgeon were reviewed retrospectively. RESULTS: Of 418 patients, 175 patients underwent low anterior resection (LAR), 172 laparoscopic abdominal transanal proctocolectomy with coloanal anastomosis (LATA), and 71 abdominoperineal resection (APR)...
December 12, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29231608/-influence-of-electroacupuncture-pretreatment-on-intestinal-function-in-the-patients-of-colorectal-cancer-surgery
#7
Sicong Mai, Jinhai Meng, Wenjuan Wang, Shuhui Lang
OBJECTIVE: To observe the effects of electroacupuncture (EA) pretreatment on the intestinal function, inflammatory reaction and blood lactic acid in the patients of colorectal cancer surgery. METHODS: Sixty patients of colorectal cancer laparotomy at selective period, aged from 18 to 59 years old were selected. According toⅠ-Ⅲ grade of American Society of Anesthesiologists (ASA), the patients were randomized into group A (total intravenous anesthesia), group B[total intravenous anesthesia combined with EA pretreatment at Zusanli (ST 36), Shangjuxu (ST 37) and Xiajuxu (ST 39) on the right side] and group C[total intravenous anesthesia combined with EA pretreatment at Zhongwan (CV 12), Tianshu (ST 25), Zusanli (ST 36), Shangjuxu (ST 37) and Xiajuxu (ST 39) on the right side], 20 cases in each one...
May 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29230591/intraoperative-use-of-icg-fluorescence-imaging-to-reduce-the-risk-of-anastomotic-leakage-in-colorectal-surgery-a-systematic-review-and-meta-analysis
#8
REVIEW
R Blanco-Colino, E Espin-Basany
BACKGROUND: Indocyanine green (ICG) fluorescence imaging has been proven to be an effective tool to assess anastomotic perfusion. The aim of this systematic review and meta-analysis was to evaluate its efficacy in reducing the anastomotic leakage (AL) rate after colorectal surgery. METHODS: PubMed, Scopus, WOS, Google Scholar and Cochrane Library were searched up to January 2017 for studies comparing fluorescence imaging with standard care. ClinicalTrials.gov register was searched for ongoing trials...
December 11, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29230127/intraarterial-liver-directed-therapies-the-role-of-interventional-oncology
#9
REVIEW
Jenson Ma, Juan Martin Gimenez, Tyler Sandow, Daniel Devun, David Kirsch, Paul Gulotta, Patrick Gilbert, Dennis Kay
Background: Since the early 1990s, the minimally invasive image-guided therapies used in interventional oncology to treat hepatocellular carcinoma have continued to evolve. Additionally, the range of applications has been expanded to the treatment of hepatic metastases from colorectal cancer, neuroendocrine tumors, cholangiocarcinoma, breast cancer, melanoma, and sarcoma. Methods: We searched the literature to identify publications from 1990 to the present on various image-guided intraarterial therapies and their efficacy, as well as their role in the management of primary and secondary liver malignancies...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/29224985/management-and-prognosis-of-locally-recurrent-rectal-cancer-a-national-population-based-study
#10
Karin Westberg, Gabriella Palmer, Fredrik Hjern, Hemming Johansson, Torbjörn Holm, Anna Martling
BACKGROUND: The rate of local recurrence of rectal cancer (LRRC) has decreased but the condition remains a therapeutic challenge. This study aimed to examine treatment and prognosis in patients with LRRC in Sweden. Special focus was directed towards potential differences between geographical regions and time periods. METHOD: All patients with LRRC as first event, following primary surgery for rectal cancer performed during the period 1995-2002, were included in this national population-based cohort-study...
November 26, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29219923/multimodal-use-of-fluorescent-imaging-in-colorectal-cancer-surgery
#11
Deborah S Keller, Juan Ramon Flores Gonzalez, Manish Chand
No abstract text is available yet for this article.
January 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29219230/similar-length-of-colon-is-removed-regardless-of-localization-in-right-sided-colonic-cancer-surgery
#12
Matthieu Siebert, Bertrand Trilling, Anna Lamotte, Nicolas Taton, Alexandre Bellier, Jean Luc Faucheron
BACKGROUND: Colorectal cancers represent a heterogenous group of tumours. While left segmental colectomy is an accepted and oncologically safe practice for left-sided colonic cancer (CC), some authors suggest that limited segmental resection of right-sided cancer should be debated in order to preserve length of the resected colon. To our knowledge, caecum and ascending CC have not been analysed as different groups of tumours. The objective of this study was to assess if, retrospectively, surgical treatment of caecal cancer differed from ascending CC...
December 8, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29218672/effect-of-academic-status-on-outcomes-of-surgery-for-rectal-cancer
#13
Kristen Cagino, Maria S Altieri, Jie Yang, Lizhou Nie, Mark Talamini, Konstantinos Spaniolas, Paula Denoya, Aurora Pryor
BACKGROUND: The purpose of our study was to investigate surgical outcomes following advanced colorectal procedures at academic versus community institutions. METHODS: The SPARCS database was used to identify patients undergoing Abdominoperineal resection (APR) and Low Anterior Resection between 2009 and 2014. Linear mixed models and generalized linear mixed models were used to compare outcomes. Laparoscopic versus open procedures, surgery type, volume status, and stoma formation between academic and community facilities were compared...
December 7, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29217904/comparison-of-the-short-term-outcomes-of-laparoscopic-and-open-resections-for-colorectal-cancer-in-patients-with-a-history-of-prior-median-laparotomy
#14
Young Wan Kim, Ik Yong Kim
This study aimed to investigate the short-term outcomes of laparoscopic resection in comparison with those of open resection for colorectal cancer in patients with a history of prior median laparotomy (PML). Eighty-seven consecutive patients (87/1121, 7.8 %) with a history of PML who underwent major colorectal cancer resection were enrolled (laparoscopy, n = 40; open, n = 47). The conversion rate to open surgery was 25 % (n = 10). The laparoscopy group had a higher proportion of female patients (57...
December 2017: Indian Journal of Surgery
https://www.readbyqxmd.com/read/29215479/major-abdominal-and-perianal-surgery-in-crohn-s-disease-long-term-follow-up-of-australian-patients-with-crohn-s-disease
#15
James W T Toh, Nelson Wang, Christopher J Young, Matthew J F X Rickard, Anil Keshava, Peter Stewart, Viraj Kariyawasam, Rupert Leong
BACKGROUND: Most patients with Crohn's disease still require surgery despite significant advances in medical therapy, surveillance, and management strategies. OBJECTIVE: The purpose of this study was to assess surgical strategies and outcomes in Crohn's disease, including surgical recurrence and emergency surgery. DESIGN: This was a multicenter, retrospective review of a prospectively collected database. SETTINGS: A specialist-referred cohort of patients with Crohn's disease between 1970 and 2009 was studied...
January 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29214884/adjuvant-intraperitoneal-chemotherapy-for-the-treatment-of-colorectal-cancer-at-risk-for-peritoneal-carcinomatosis-a-systematic-review
#16
Paul L Feingold, Nicholas D Klemen, Mei Li M Kwong, Barry Hashimoto, Udo Rudloff
BACKGROUND: The peritoneal surface is the second most common site of disease recurrence, after the liver, following definitive surgery for colorectal cancer. Adjuvant intraperitoneal (IP) chemotherapy delivered at time of surgical resection has the potential to delay or prevent future spread to the peritoneal surface and improve clinical outcome. The exact role of adjuvant IP chemotherapy in colorectal cancer, including its associated morbidity and mortality, is not well defined. STUDY DESIGN: Systematic review and pooled random effect analysis of comparative trials examining the addition of adjuvant IP chemotherapy compared to surgery alone in colorectal cancer...
December 7, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/29208881/clinicopathological-assessment-of-colorectal-carcinoma-in-mymensingh-medical-college-hospital-bangladesh
#17
M M Mahamud, F Wahed, J Ferdous, M K Khan
Colorectal carcinoma (CRC) is the third most commonly diagnosed cancer and the third leading cause of cancer death in both men and women in the US. It is mainly a disease of the developed countries with a western culture, yet the disease is not uncommon in developing countries. There is substantial geographical variation in the incidence and demographic characteristics of the disease. Variations are also observed in the risk factors, mode of presentation, sub site distribution and stage of the disease at presentation...
October 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29208675/why-attempt-en-bloc-resection-of-non-pedunculated-colorectal-adenomas-a-systematic-review-of-the-prevalence-of-superficial-submucosal-invasive-cancer-after-endoscopic-submucosal-dissection
#18
Lorenzo Fuccio, Alessandro Repici, Cesare Hassan, Thierry Ponchon, Pradeep Bhandari, Rodrigo Jover, Konstantinos Triantafyllou, Daniele Mandolesi, Leonardo Frazzoni, Cristina Bellisario, Franco Bazzoli, Prateek Sharma, Thomas Rösch, Douglas K Rex
OBJECTIVE: Endoscopic submucosal dissection (ESD) aims to achieve en bloc resection of non-pedunculated colorectal adenomas which might be indicated in cases with superficial submucosal invasive cancers (SMIC), but the procedure is time consuming and complex. The prevalence of such cancers is not known but may determine the clinical necessity for ESD as opposed to the commonly used piecemeal mucosal resection (endoscopic mucosal resection) of colorectal adenomas. The main aim was to assess the prevalence of SMIC SM1 (ie, invasion ≤1000 µm or less than one-third of the submucosa) on colorectal lesions removed by ESD...
December 5, 2017: Gut
https://www.readbyqxmd.com/read/29203998/optimal-management-of-a-synchronous-diagnosis-of-phaeochromocytoma-and-colorectal-neoplasia
#19
Ridwaan Sohawon, Peter Truran, Jonathan Webster, Barney J Harrison, Sabapathy P Balasubramanian
The incidence rates of phaeochromocytoma and colorectal cancer (CRC) are approximately 1 and 65 per 100,000 per year, respectively. Simultaneous presentation of these conditions is rare and poses unique management challenges. We report on treatment strategies and clinical outcomes in a series of patients with colorectal neoplasia and phaeochromocytoma. Demographic and clinical details of four patients over a 4-year period were reviewed. The median (range) age at first presentation was 66 (52-70) years. Phaeochromocytoma (2...
December 2017: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29203993/minimally-invasive-surgery-for-rectal-cancer-current-status-and-future-perspectives
#20
REVIEW
Chinock Cheong, Nam Kyu Kim
Although laparoscopic resection for colon cancer has been proven safe and feasible when compared with open resection, currently no clear evidence is available regarding minimally invasive surgery for rectal cancer. This type of surgery may benefit patients by allowing fast recovery of normal dietary intake and bowel function, reduced postoperative pain, and shorter hospitalization. Therefore, minimally invasive surgeries such as laparoscopic or robot surgery have become the predominant treatment option for colon cancer...
December 2017: Indian Journal of Surgical Oncology
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