keyword
MENU ▼
Read by QxMD icon Read
search

Network perspective

keyword
https://www.readbyqxmd.com/read/29046998/metabolite-profiling-and-associated-gene-expression-reveal-two-metabolic-shifts-during-the-seed-to-seedling-transition-in-arabidopsis-thaliana
#1
Anderson Tadeu Silva, Wilco Ligterink, Henk W M Hilhorst
Metabolic and transcriptomic correlation analysis identified two distinctive profiles involved in the metabolic preparation for seed germination and seedling establishment, respectively. Transcripts were identified that may control metabolic fluxes. The transition from a quiescent metabolic state (dry seed) to the active state of a vigorous seedling is crucial in the plant's life cycle. We analysed this complex physiological trait by measuring the changes in primary metabolism that occur during the transition in order to determine which metabolic networks are operational...
October 18, 2017: Plant Molecular Biology
https://www.readbyqxmd.com/read/29042602/the-optimal-window-size-for-analysing-longitudinal-networks
#2
Shahadat Uddin, Nazim Choudhury, Sardar M Farhad, Md Towfiqur Rahman
The time interval between two snapshots is referred to as the window size. A given longitudinal network can be analysed from various actor-level perspectives, such as exploring how actors change their degree centrality values or participation statistics over time. Determining the optimal window size for the analysis of a given longitudinal network from different actor-level perspectives is a well-researched network science problem. Many researchers have attempted to develop a solution to this problem by considering different approaches; however, to date, no comprehensive and well-acknowledged solution that can be applied to various longitudinal networks has been found...
October 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29039271/social-multiplier-effects-academics-and-practitioners-perspective-on-the-benefits-of-a-tuberculosis-operational-research-capacity-building-program-in-indonesia
#3
Ari Probandari, Yodi Mahendradhata, Bagoes Widjanarko, Bachti Alisjahbana
BACKGROUND: The Tuberculosis Operational Research Group (TORG) implemented a capacity-building model involving academics and practitioners (i.e. clinicians or program staff) in an operational research (OR) team in Indonesia. OBJECTIVE: This study explored academics' and practitioners' perspectives regarding the benefits of participating in a tuberculosis (TB) OR capacity-building program in Indonesia. METHODS: We conducted a qualitative study involving in-depth interviews with 36 academics and 23 practitioners undertaking the TORG capacity-building program...
2017: Global Health Action
https://www.readbyqxmd.com/read/29037451/-city-hospital-network-and-quality-control-of-officinal-preparations
#4
C Curti, S Gallice, E Lamy, P Rathelot, P Vanelle
OBJECTIVES: In a hospital environment, the quality control of the hospital preparations allows to release homogeneous batches in a secure way. These controls are totally integrated into the process of production and can also, in certain cases, be realized for high-alert magistral preparations. In community pharmacy, these controls were not required, but the Agence régionale de santé (ARS) recently incited compounding community pharmacies to realize this type of analyses. This decision motivated the creation of a collaboration between the pharmacy department of a French teaching hospital and a society including around thirty community pharmacies having a preparatory...
October 13, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/29036877/a-hybrid-cnn-feature-model-for-pulmonary-nodule-malignancy-risk-differentiation
#5
Huafeng Wang, Tingting Zhao, Lihong Connie Li, Haixia Pan, Wanquan Liu, Haoqi Gao, Fangfang Han, Yuehai Wang, YiFang Qi, Zhengrong Liang
The malignancy risk differentiation of pulmonary nodule is one of the most challenge tasks of computer-aided diagnosis (CADx). Most recently reported CADx methods or schemes based on texture and shape estimation have shown relatively satisfactory on differentiating the risk level of malignancy among the nodules detected in lung cancer screening. However, the existing CADx schemes tend to detect and analyze characteristics of pulmonary nodules from a statistical perspective according to local features only. Enlightened by the currently prevailing learning ability of convolutional neural network (CNN), which simulates human neural network for target recognition and our previously research on texture features, we present a hybrid model that takes into consideration of both global and local features for pulmonary nodule differentiation using the largest public database founded by the Lung Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI)...
October 10, 2017: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/29035235/asymmetric-game-a-silver-bullet-to-weighted-vertex-cover-of-networks
#6
Changbing Tang, Ang Li, Xiang Li
Weighted vertex cover (WVC), a generalized type of vertex cover, is one of the most important combinatorial optimization problems. In this paper, we provide a novel solution to the WVC problem from the view of network engineering. We model the WVC problem as an asymmetric game on weighted networks, where each vertex is treated as an intelligent rational agent rather than an inanimate one. Under the framework of asymmetric game, we find that strict Nash equilibriums of the asymmetric game are the intermediate states between the WVC states and the minimum WVC (MWVC) states...
October 16, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/29034553/synthesis-of-anisotropic-hydrogels-and-their-applications
#7
Koki Sano, Yasuhiro Ishida, Takuzo Aida
Owing to their water-rich structures similar to biological tissues, hydrogels have long been regarded as promising scaffolds for artificial tissues and organs. However, in terms of structural anisotropy, most synthetic hydrogels are substantially different from biological systems. Synthetic hydrogels are usually composed of randomly oriented three-dimensional polymer networks, whereas biological systems adopt anisotropic structures with hierarchically integrated building units. Such anisotropic structures often play an essential role in biological systems to exhibit their particular functions, as represented by muscular textures comprising unidirectionally oriented actin-myosin units...
October 16, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/29033968/dancing-with-hormones-a-current-perspective-of-nitrate-signaling-and-regulation-in-arabidopsis
#8
REVIEW
Peizhu Guan
In nature and agriculture, nitrate availability is a main environmental cue for plant growth, development and stress responses. Nitrate signaling and regulation are hence at the center of communications between plant intrinsic programs and the environment. It is also well known that endogenous phytohormones play numerous critical roles in integrating extrinsic cues and intrinsic responses, regulating and refining almost all aspects of plant growth, development and stress responses. Therefore, interaction between nitrate and phytohormones, such as auxins, cytokinins, abscisic acid, gibberellins, and ethylene, is prevalent...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29032703/the-use-of-telepsychiatry-to-provide-cost-efficient-care-during-pediatric-mental-health-emergencies
#9
John F Thomas, Douglas K Novins, Patrick W Hosokawa, Christina A Olson, Dru Hunter, Alison S Brent, Gerard Frunzi, Anne M Libby
OBJECTIVE: This study evaluated a videoconference-based psychiatric emergency consultation program (telepsychiatry) at geographically dispersed emergency department (ED) sites that are part of the network of care of an academic children's hospital system. The study compared program outcomes with those of usual care involving ambulance transport to the hospital for in-person psychiatric emergency consultation prior to disposition to inpatient care or discharge home. METHODS: This study compared process outcomes in a cross-sectional, pre-post design at five network-of-care sites before and after systemwide implementation of telepsychiatry consultation in 2015...
October 16, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29032442/the-influence-of-peers-during-adolescence-does-homophobic-name-calling-by-peers-change-gender-identity
#10
Dawn DeLay, Carol Lynn Martin, Rachel E Cook, Laura D Hanish
Adolescents actively evaluate their identities during adolescence, and one of the most salient and central identities for youth concerns their gender identity. Experiences with peers may inform gender identity. Unfortunately, many youth experience homophobic name calling, a form of peer victimization, and it is unknown whether youth internalize these peer messages and how these messages might influence gender identity. The goal of the present study was to assess the role of homophobic name calling on changes over the course of an academic year in adolescents' gender identity...
October 14, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/29031465/neurocognitive-mechanisms-of-the-flow-state
#11
David J Harris, Samuel J Vine, Mark R Wilson
While the experience of flow is often described in attentional terms-focused concentration or task absorption-specific cognitive mechanisms have received limited interest. We propose that an attentional explanation provides the best way to advance theoretical models and produce practical applications, as well as providing potential solutions to core issues such as how an objectively difficult task can be subjectively effortless. Recent research has begun to utilize brain-imaging techniques to investigate neurocognitive changes during flow, which enables attentional mechanisms to be understood in greater detail...
2017: Progress in Brain Research
https://www.readbyqxmd.com/read/29031263/2d-ir-spectroscopy-of-high-pressure-phases-of-ice
#12
Halina Tran, Ana V Cunha, Jacob J Shephard, Andrey Shalit, Peter Hamm, Thomas L C Jansen, Christoph G Salzmann
We present experimental and simulated 2D IR spectra of some high-pressure forms of isotope-pure D2O ice and compare the results to those of ice Ih published previously [F. Perakis and P. Hamm, Phys. Chem. Chem. Phys. 14, 6250 (2012); L. Shi et al., ibid. 18, 3772 (2016)]. Ice II, ice V, and ice XIII have been chosen for this study, since this selection covers many aspects of the polymorphism of ice. That is, ice II is a hydrogen-ordered phase of ice, in contrast to ice Ih, while ice V and ice XIII are a hydrogen-disordered/ordered couple that shares essentially the same oxygen structure and hydrogen-bonded network...
October 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29031097/the-tall-and-the-short-of-it-an-investigation-of-height-ideals-height-preferences-height-dissatisfaction-heightism-and-height-related-quality-of-life-impairment-among-sexual-minority-men
#13
Scott Griffiths, Stuart B Murray, Aimee Medeiros, Aaron J Blashill
Human height has attracted empirical interest from a variety of psychological perspectives. However, little research has explored height from the perspective of sexual minority men, inclusive of their height beliefs, height preferences, height dissatisfaction, experiences of heightism, and height-related quality of life impairment. We explored these height variables in 2733 sexual minority men who completed a survey distributed nationwide to Australian and New Zealander users of geosocial-networking smartphone applications...
October 11, 2017: Body Image
https://www.readbyqxmd.com/read/29030730/introduction-eric-davidson-and-the-molecular-biology-of-evolution-and-development
#14
EDITORIAL
Michel Morange, Ute Deichmann
Between November 30th and December 2nd, 2015, the Jacques Loeb Centre for the History and Philosophy of the Life Sciences at Ben-Gurion University of the Negev in Beer Sheva (Israel) held its Eighth International Workshop under the title "From Genome to Gene: Causality, Synthesis and Evolution". Eric Davidson, the founder of the concept of developmental Gene Regulatory Networks, had regularly attended the previous meetings, and his participation in this one was expected, but he suddenly passed away 3 months before...
October 13, 2017: History and Philosophy of the Life Sciences
https://www.readbyqxmd.com/read/29029759/patient-centered-research-priorities-in-ovarian-cancer-a-systematic-review-of-potential-determinants-of-guideline-care
#15
REVIEW
Rachel A Pozzar, Donna L Berry
OBJECTIVE: To (a) determine what is known about the individual and contextual factors that may influence whether a woman with ovarian cancer receives guideline care, and (b) identify patient-centered research priorities in ovarian cancer. METHODS: A systematic review of the PubMed, MEDLINE, CINAHL Complete, and PsycInfo online databases. Eligible articles were published in English, described original research, and either (a) identified factors associated with the receipt of guideline care for ovarian cancer, or (b) described treatment decision making by women with ovarian cancer...
October 10, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/29029299/weak-regulation-of-many-targets-is-cumulatively-powerful-an-evolutionary-perspective-on-microrna-functionality
#16
Yixin Zhao, Xu Shen, Tian Tang, Chung-I Wu
Why do microRNAs (miRNAs) weakly repress so many targets such that most targets do not have phenotypic effects? An increasingly accepted view posits that weak targeting has no biological function and each miRNA effectively has only a few functional targets. Here, we review the evolutionary arguments for this postulate and find these arguments seriously flawed. In contrast, from the systems perspective, the power of broad and weak targeting may reside in the cumulative effects of all expressions, which collectively stabilize gene regulatory networks...
September 28, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/29028982/trove-a-user-friendly-tool-for-visualizing-and-analyzing-cancer-hallmarks-in-signaling-networks
#17
Huey Eng Chua, Sourav S Bhowmick, Jie Zheng
Summary: Cancer hallmarks, a concept that seeks to explain the complexity of cancer initiation and development, provide a new perspective of studying cancer signaling which could lead to a greater understanding of this complex disease. However, to the best of our knowledge, there is currently a lack of tools that support such hallmark-based study of the cancer signaling network, thereby impeding the gain of knowledge in this area. We present TROVE, a user-friendly software that facilitates hallmark annotation, visualization and analysis in cancer signaling networks...
September 22, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29028203/an-information-theoretical-analysis-of-human-insulin-glucose-system-towards-the-internet-of-bio-nano-things
#18
Naveed A Abbasi, Ozgur B Akan
Molecular communication is an important tool to understand biological communications with many promising applications in Internet of Bio-Nano Things (IoBNT). The insulinglucose system is of key significance among the major intrabody nanonetworks since it fulfills metabolic requirements of the body. Study of biological networks from information and communication theoretical (ICT) perspective is necessary for their introduction in the IoBNT framework. Therefore, the objective of this work is to provide and analyze for the first time in literature, a simple molecular communication model of the human insulin-glucose system from ICT perspective...
October 11, 2017: IEEE Transactions on Nanobioscience
https://www.readbyqxmd.com/read/29028058/protein-protein-interaction-networks-as-a-new-perspective-to-evaluate-distinct-functional-roles-of-voltage-dependent-anion-channel-isoforms
#19
REVIEW
Marianna Caterino, Margherita Ruoppolo, Annalisa Mandola, Michele Costanzo, Stefania Orrù, Esther Imperlini
Voltage-dependent anion channels (VDACs) are a family of three mitochondrial porins and the most abundant integral membrane proteins of the mitochondrial outer membrane (MOM). VDACs are known to be involved in metabolite/ion transport across the MOM and in many cellular processes ranging from mitochondria-mediated apoptosis to the control of energy metabolism, by interacting with cytosolic, mitochondrial and cytoskeletal proteins and other membrane channels. Despite redundancy and compensatory mechanisms among VDAC isoforms, they display not only different channel properties and protein expression levels, but also distinct protein partners...
October 13, 2017: Molecular BioSystems
https://www.readbyqxmd.com/read/29027979/molecular-mechanics-of-the-moisture-effect-on-epoxy-carbon-nanotube-nanocomposites
#20
Lik-Ho Tam, Chao Wu
The strong structural integrity of polymer nanocomposite is influenced in the moist environment; but the fundamental mechanism is unclear, including the basis for the interactions between the absorbed water molecules and the structure, which prevents us from predicting the durability of its applications across multiple scales. In this research, a molecular dynamics model of the epoxy/single-walled carbon nanotube (SWCNT) nanocomposite is constructed to explore the mechanism of the moisture effect, and an analysis of the molecular interactions is provided by focusing on the hydrogen bond (H-bond) network inside the nanocomposite structure...
October 13, 2017: Nanomaterials
keyword
keyword
27680
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"