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https://www.readbyqxmd.com/read/28723811/the-afya-bora-fellowship-an-innovative-program-focused-on-creating-an-interprofessional-network-of-leaders-in-global-health
#1
Wendy M Green, Carey Farquhar, Yohana Mashalla
PROBLEM: Most current health professions education programs are focused on the development of clinical skills. As a result, they may not address the complex and interconnected nature of global health. Trainees require relevant clinical, programmatic, and leadership skills to meet the challenges of practicing in an increasingly globalized environment. APPROACH: To develop health care leaders within sub-Saharan Africa, the Afya Bora Consortium developed a one-year fellowship for medical doctors and nurses...
July 18, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28721821/current-perspectives-for-the-use-of-gonane-progesteronergic-drugs-in-the-treatment-of-central-hypoventilation-syndromes
#2
Camille Loiseau, Florence Cayetanot, Fanny Joubert, Anne-Sophie Perrin-Terrin, Philippe Cardot, Marie-Noëlle Fiamma, Alain Frugiere, Christian Straus, Laurence Bodineau
BACKGROUND: Central alveolar hypoventilation syndromes (CHS) encompass neurorespiratory diseases resulting from congenital or acquired neurological disorders. Hypercapnia, acidosis, and hypoxemia resulting from CHS negatively affect physiological functions and can be life-threatening. To date, the absence of pharmacological treatment implies that the patients must receive assisted ventilation throughout their lives. OBJECTIVE: To highlight the relevance of determining conditions in which using gonane synthetic progestins could be of potential clinical interest for the treatment of CHS...
July 19, 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/28720794/percolation-theoretic-bounds-on-the-cache-size-of-nodes-in-mobile-opportunistic-networks
#3
Peiyan Yuan, Honghai Wu, Xiaoyan Zhao, Zhengnan Dong
The node buffer size has a large influence on the performance of Mobile Opportunistic Networks (MONs). This is mainly because each node should temporarily cache packets to deal with the intermittently connected links. In this paper, we study fundamental bounds on node buffer size below which the network system can not achieve the expected performance such as the transmission delay and packet delivery ratio. Given the condition that each link has the same probability p to be active in the next time slot when the link is inactive and q to be inactive when the link is active, there exists a critical value p c from a percolation perspective...
July 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28717517/knowledge-mapping-visualization-analysis-of-the-military-health-and-medicine-papers-published-in-the-web-of-science-over-the-past-10%C3%A2-years
#4
Xuan-Ming Zhang, Xuan Zhang, Xu Luo, Hai-Tao Guo, Li-Qun Zhang, Ji-Wei Guo
BACKGROUND: Military medicine is a research field that seeks to solve the medical problems that occur in modern war conditions based on public medicine theory. METHODS: We explore the main research topics of military health and medical research in the web of science™ core collection (WoSCC) from 2007 to 2016, and the goal of this work is to serve as a reference for orientation and development in military health and medicine. Based on CiteSpace III, a reference co-citation analysis is performed for 7921 papers published in the WoSCC from 2007 to 2016...
2017: Military Medical Research
https://www.readbyqxmd.com/read/28717214/cumulative-dynamics-of-independent-information-spreading-behaviour-a-physical-perspective
#5
Cangqi Zhou, Qianchuan Zhao, Wenbo Lu
The popularization of information spreading in online social networks facilitates daily communication among people. Although much work has been done to study the effect of interactions among people on spreading, there is less work that considers the pattern of spreading behaviour when people independently make their decisions. By comparing microblogging, an important medium for information spreading, with the disordered spin glass system, we find that there exist interesting corresponding relationships between them...
July 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28716209/understanding-animal-health-communication-networks-among-smallholder-livestock-producers-in-australia-using-stakeholder-analysis
#6
L Hayes, R Woodgate, L Rast, J-A L M L Toribio, M Hernández-Jover
Smallholder livestock producers are a diverse population with wide ranging motivations for keeping livestock. The biosecurity risk posed by smallholders has been the subject of much conjecture, with comparisons often made between the level of animal health and biosecurity knowledge of smallholders, versus that of commercial livestock producers. This research aimed to gain a better understanding of current knowledge of smallholder production in Australia, particularly in relation to biosecurity and emergency animal disease, and to investigate the relationships that exist between smallholders and the organisations and individuals from which they seek information, assistance and support...
September 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28713927/classifier-of-cross-talk-genes-predicts-the-prognosis-of-hepatocellular-carcinoma
#7
Xiaofeng Zhai, Qingfeng Xue, Qun Liu, Yuyu Guo, Zhe Chen
The present study aimed to establish a prediction model for hepatocellular carcinoma (HCC) based on the cross talk genes from important biological pathways involved in HCC. Differentially expressed genes (DEGs) for HCC were identified from mRNA profiles of GSE36376, which were mapped to protein‑protein interaction (PPI) networks from BioGrid and the human protein reference database. Then critical genes based on the deviation score and the degree of node were selected from the novel PPI network. Cross talk genes were screened from the network established based on the associations of gene‑gene, gene‑pathway and pathway‑pathway...
July 15, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28713320/social-media-membership-browsing-and-profile-updating-in-a-representative-u-s-sample-independent-and-interdependent-effects-of-big-five-traits-and-aging-and-social-factors
#8
Tim Bogg
Guided by cybernetic perspectives on personality, the present work used a representative sample of U.S. adults (N = 992) to examine Big Five personality traits and social and aging factors as predictors of social media network membership and past-month browsing/searching and profile updating among members. The results showed adults who were less extraverted and less neurotic and who reported greater physical limitations were less likely to be members. Moreover, extraverted adults without partners were more likely to be members than introverted adults without partners...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28713244/regulatory-roles-of-long-non-coding-rnas-in-the-central-nervous-system-and-associated-neurodegenerative-diseases
#9
REVIEW
Zhenzhen Quan, Da Zheng, Hong Qing
Accumulating studies have revealed that the human genome encodes tens of thousands of long non-coding RNAs (lncRNAs), which participate in multiple biological networks modulating gene expression via transcriptional, post-transcriptional and epigenetic regulation. Strikingly, a large fraction of tissue-specific lncRNAs are expressed in the Central Nervous System (CNS) with precisely regulated temporal and spatial expression patterns. These brain-specific lncRNAs are also featured with the cell-type specificity, the highest signals of evolutionary conservation, and their preferential location adjacent to brain-expressed protein-coding genes...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28711863/drivers-social-work-relationships-as-antecedents-of-unsafe-driving-a-social-network-perspective
#10
Renana Arizon Peretz, Gil Luria
In order to reduce road accidents rates, studies around the globe have attempted to shed light on the antecedents for unsafe road behaviors. The aim of the current research is to contribute to this literature by offering a new organizational antecedent of driver's unsafe behavior: The driver's relationships with his or her peers, as reflected in three types of social networks: negative relationships network, friendship networks and advice networks (safety consulting). We hypothesized that a driver's position in negative relationship networks, friendship networks, and advice networks will predict unsafe driving...
July 13, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28711720/onset-age-of-l2-acquisition-influences-language-network-in-early-and-late-cantonese-mandarin-bilinguals
#11
Xiaojin Liu, Liu Tu, Junjing Wang, Bo Jiang, Wei Gao, Ximin Pan, Meng Li, Miao Zhong, Zhenzhen Zhu, Meiqi Niu, Yanyan Li, Ling Zhao, Xiaoxi Chen, Chang Liu, Zhi Lu, Ruiwang Huang
Early second language (L2) experience influences the neural organization of L2 in neuro-plastic terms. Previous studies tried to reveal these plastic effects of age of second language acquisition (AoA-L2) and proficiency-level in L2 (PL-L2) on the neural basis of language processing in bilinguals. Although different activation patterns have been observed during language processing in early and late bilinguals by task-fMRI, few studies reported the effect of AoA-L2 and high PL-L2 on language network at resting state...
July 13, 2017: Brain and Language
https://www.readbyqxmd.com/read/28710589/primary-care-physician-perspectives-on-barriers-to-statin-treatment
#12
Rikki M Tanner, Monika M Safford, Keri L Monda, Benjamin Taylor, Ronan O'Beirne, Melanie Morris, Lisandro D Colantonio, Ricardo Dent, Paul Muntner, Robert S Rosenson
PURPOSE: Discontinuation of statin therapy represents a major challenge for effective cardiovascular disease prevention. It is unclear how often primary care physicians (PCPs) re-initiate statins and what barriers they encounter. We aimed to identify PCP perspectives on factors influencing statin re-initiation. METHODS: We conducted six nominal group discussions with 23 PCPs from the Deep South Continuing Medical Education network. PCPs answered questions about statin side effects, reasons their patients reported for discontinuing statins, how they respond when discontinuation is reported, and barriers they encounter in getting their patients to re-initiate statin therapy...
July 14, 2017: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/28710516/perspectives-and-challenges-of-photon-upconversion-nanoparticles-part-i-routes-to-brighter-particles-and-quantitative-spectroscopic-studies
#13
REVIEW
Ute Resch-Genger, Hans H Gorris
Lanthanide-doped photon-upconversion nanoparticles (UCNPs) have been the focus of many research activities in materials and life sciences in the last 15 years because of their potential to convert light between different spectral regions and their unique photophysical properties. To fully exploit the application potential of these fascinating nanomaterials, a number of challenges have to be overcome, such as the low brightness, particularly of small UCNPs, and the reliable quantification of the excitation-power-density-dependent upconversion luminescence...
July 14, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28710222/a-developmental-evaluation-to-enhance-stakeholder-engagement-in-a-wide-scale-interactive-project-disseminating-quality-improvement-data-study-protocol-for-a-mixed-methods-study
#14
Alison Laycock, Jodie Bailie, Veronica Matthews, Frances Cunningham, Gillian Harvey, Nikki Percival, Ross Bailie
INTRODUCTION: Bringing together continuous quality improvement (CQI) data from multiple health services offers opportunities to identify common improvement priorities and to develop interventions at various system levels to achieve large-scale improvement in care. An important principle of CQI is practitioner participation in interpreting data and planning evidence-based change. This study will contribute knowledge about engaging diverse stakeholders in collaborative and theoretically informed processes to identify and address priority evidence-practice gaps in care delivery...
July 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28710210/being-normal-not-vulnerable-case-study-of-a-2-day-residential-programme-for-young-adults-with-cancer
#15
Ana Martins, Rachel M Taylor, Sue Morgan, Lorna A Fern
OBJECTIVES: To identify and describe the outcomes and facilitating processes of participation at 'Find Your Sense of Tumour' (FYSOT), a 2-day residential programme/conference for young people with cancer, from the perspective of professionals attending and patient representatives. DESIGN: Case study. SETTING: Observation of the 'Find Your Sense of Tumour' over 18s residential programme and face-to-face interviews in hospital and phone interviews...
July 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28709274/coherence-of-biochemical-oscillations-is-bounded-by-driving-force-and-network-topology
#16
Andre C Barato, Udo Seifert
Biochemical oscillations are prevalent in living organisms. Systems with a small number of constituents cannot sustain coherent oscillations for an indefinite time because of fluctuations in the period of oscillation. We show that the number of coherent oscillations that quantifies the precision of the oscillator is universally bounded by the thermodynamic force that drives the system out of equilibrium and by the topology of the underlying biochemical network of states. Our results are valid for arbitrary Markov processes, which are commonly used to model biochemical reactions...
June 2017: Physical Review. E
https://www.readbyqxmd.com/read/28709252/magnetorheological-response-of-highly-filled-magnetoactive-elastomers-from-perspective-of-mechanical-energy-density-fractal-aggregates-above-the-nanometer-scale
#17
Vladislav V Sorokin, Inna A Belyaeva, Mikhail Shamonin, Elena Yu Kramarenko
The dynamic shear modulus of magnetoactive elastomers containing 70 and 80 mass % of carbonyl iron microparticles is measured as a function of strain amplitude via dynamic torsion oscillations in various magnetic fields. The results are presented in terms of the mechanical energy density and considered in the framework of the conventional Kraus model. The form exponent of the Kraus model is further related to a physical model of Huber et al. [Huber et al., J. Phys.: Condens. Matter 8, 409 (1996)10.1088/0953-8984/8/29/003] that uses a realistic representation for the cluster network possessing fractal structure...
June 2017: Physical Review. E
https://www.readbyqxmd.com/read/28709103/end-user-perspective-of-low-cost-sensors-for-outdoor-air-pollution-monitoring
#18
REVIEW
Aakash C Rai, Prashant Kumar, Francesco Pilla, Andreas N Skouloudis, Silvana Di Sabatino, Carlo Ratti, Ansar Yasar, David Rickerby
Low-cost sensor technology can potentially revolutionise the area of air pollution monitoring by providing high-density spatiotemporal pollution data. Such data can be utilised for supplementing traditional pollution monitoring, improving exposure estimates, and raising community awareness about air pollution. However, data quality remains a major concern that hinders the widespread adoption of low-cost sensor technology. Unreliable data may mislead unsuspecting users and potentially lead to alarming consequences such as reporting acceptable air pollutant levels when they are above the limits deemed safe for human health...
July 11, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28709026/regulation-of-calcium-and-magnesium-homeostasis-in-plants-from-transporters-to-signaling-network
#19
REVIEW
Ren-Jie Tang, Sheng Luan
Calcium (Ca(2+)) and magnesium (Mg(2+)) are the most abundant divalent cations in plants. As a nutrient and a signaling ion, Ca(2+) levels in the cell are tightly controlled by an array of channels and carriers that provide mechanistic basis for Ca(2+) homeostasis and the generation of Ca(2+) signals. Although a family of CorA-type Mg(2+) transporters plays a key role in controlling Mg(2+) homeostasis in plants, more components are yet to be identified. Ca(2+) and Mg(2+) appear to have antagonistic interactions in plant cells, and therefore plants depend on a homeostatic balance between Ca(2+) and Mg(2+) for optimal growth and development...
July 11, 2017: Current Opinion in Plant Biology
https://www.readbyqxmd.com/read/28705115/microrna-21-versus-microrna-34-lung-cancer-promoting-and-inhibitory-micrornas-analysed-in-silico-and-in-vitro-and-their-clinical-impact
#20
Meik Kunz, Claudia Göttlich, Thorsten Walles, Sarah Nietzer, Gudrun Dandekar, Thomas Dandekar
MicroRNAs are well-known strong RNA regulators modulating whole functional units in complex signaling networks. Regarding clinical application, they have potential as biomarkers for prognosis, diagnosis, and therapy. In this review, we focus on two microRNAs centrally involved in lung cancer progression. MicroRNA-21 promotes and microRNA-34 inhibits cancer progression. We elucidate here involved pathways and imbed these antagonistic microRNAs in a network of interactions, stressing their cancer microRNA biology, followed by experimental and bioinformatics analysis of such microRNAs and their targets...
July 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
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