keyword
https://read.qxmd.com/read/38653008/%C3%AE-hydroxybutyrate-exposure-restores-mitochondrial-function-in-skeletal-muscle-satellite-cells-of-critically-ill-patients
#21
JOURNAL ARTICLE
Lucie Genserová, František Duška, Adéla Krajčová
BACKGROUND & AIM: Dysfunction of skeletal muscle satellite cells might impair muscle regeneration and prolong ICU-acquired weakness, a condition associated with disability and delayed death. This study aimed to elucidate the distinct metabolic effects of critical illness and β-OH-butyrate on satellite cells isolated from these patients. METHODS: Satellite cells were extracted from vastus lateralis muscle biopsies of patients with ICU-acquired weakness (n = 10) and control group of healthy volunteers or patients undergoing elective hip replacement surgery (n = 10)...
April 9, 2024: Clinical Nutrition
https://read.qxmd.com/read/38652346/-the-least-significant-change-on-bone-mineral-density-scan-increased-in-patients-with-higher-degrees-of-obesity
#22
JOURNAL ARTICLE
Claire Dorilleau, Lukshe Kanagaratnam, Isabelle Charlot, Ambre Hittinger, Eric Bertin, Jean-Hugues Salmon, Marion Geoffroy
BACKGROUND: The least significant change (LSC) threshold of 0.03 g/cm² is used to interpret bone mineral density (BMD) scans in the general population. Our working hypothesis was that the current LSC threshold would not be applicable in obese populations. AIMS: The aim of this study was to calculate the LSC in an obese population. METHODS: We performed an interventional study among 120 obesity patients, in whom two measurements of BMD were performed at 3 sites...
April 23, 2024: Aging Clinical and Experimental Research
https://read.qxmd.com/read/38652254/an-anatomic-consideration-of-the-femoral-nerve-during-direct-anterior-hip-approach-a-cadaveric-study
#23
JOURNAL ARTICLE
Witchaporn Witayakom, Kamolsak Sukhonthamarn, Weerachai Kosuwon, Rit Apinyankul
PURPOSE: This study aimed to investigate the distance and correlation between the anatomy of the anterior side of the hip joint and the femoral nerve. METHODS: Using ten fresh-frozen cadavers with twenty hip joints. We dissected and marked the femoral nerve in the inguinal area. Employing the direct anterior approach, we identified and marked study points, including the superior and inferior points of the anterior rim of the acetabulum, ¼ point, half point, and ¾ point along an imagined line connecting the formers, the inferomedial and mid aspect of the femoral neck, and the soft spot...
April 23, 2024: Surgical and Radiologic Anatomy: SRA
https://read.qxmd.com/read/38652245/long-stem-revision-versus-short-stem-revision-with-plate-osteosynthesis-for-vancouver-type-b2-periprosthetic-femoral-fracture-a-comparative-study-of-eighty-five-cases
#24
JOURNAL ARTICLE
Jian-Jiun Chen, Shih-Hsin Hung, Jia-You Liou, Wen-Chieh Chang, Kuei-Hsiang Hsu, Yu-Pin Su, Fang-Yao Chiu, Ming-Fai Cheng
PURPOSE: Periprosthetic femoral fractures (PPFs) around the hip are challenging complications in orthopaedic surgery, particularly Vancouver type B2 (VTB2) fractures. The surgical management of these fractures is crucial and depends on various factors. Cementless short taper stem with plate osteosynthesis is an alternative surgical technique. This study aims to compare the outcomes of this surgical technique with revision arthroplasty (RA) with long stem in the treatment of VTB2 PPFs...
April 23, 2024: International Orthopaedics
https://read.qxmd.com/read/38652158/development-and-validation-of-models-for-predicting-mortality-in-intertrochanteric-fracture-surgery-patients-with-perioperative-blood-transfusion-a-prospective-multicenter-cohort-study
#25
JOURNAL ARTICLE
Junfei Guo, Qian Geng, Ke Xu, Wensen Jing, Zheng Li, Jinwen He, Ying Pan, Yanan Li, Tao Wang, Yubin Long, Zhiyong Hou, Xin Xu, Peng Xu
BACKGROUND: The association between allogenic blood transfusions (ABT) and all-cause mortality in surgically treated hip fracture patients with perioperative transfusion (STHFPT) remained unknown. We aim to introduce transfusion-related factors, new variables to develop and validate models to predict mortality in these patients. METHODS: A prospective multicenter cohort study was conducted with STHFPT hospitalized during Jan. 2018 and Jun. 2021. The database was divided into training cohort and validation cohort in a ratio of 70% to 30% using the randomization method...
April 23, 2024: International Journal of Surgery
https://read.qxmd.com/read/38651560/fulminant-heterotopic-ossification-of-the-lower-extremity-after-gunshot-injury-and-blunt-trauma-a-case-report
#26
JOURNAL ARTICLE
Katharina Estel, David Alexander Back, Catharina Scheuermann-Poley, Christian Willy
Traumatic heterotopic ossification (HO) of the lower extremity is relatively rare but is of major importance in clinical practice. They are defined as posttraumatic abnormal formations of bone within soft tissue outside of the skeletal system. This article describes the clinical case of a 31-year-old male patient who suffered 2 traumatic events within 12 months-a gunshot wound in the lumbar spine/gluteal region followed by a severe traumatic brain injury with intracranial hemorrhage in a traffic accident as a pedestrian...
April 23, 2024: Military Medicine
https://read.qxmd.com/read/38651529/pathogenic-gene-variants-identified-in-patients-presenting-with-perthes-or-perthes-like-hip-disorder
#27
JOURNAL ARTICLE
Gabrielle Marchelli, Candelaria Mercado, Corey S Gill, Harry K W Kim
AIMS: Legg-Calve-Perthes disease (LCPD) is a diagnosis of exclusion. Various conditions, such as skeletal dysplasias, can closely mimic LCPD and these must be ruled out to provide appropriate treatment, prognosis, and counseling. Traditionally, genetic testing has not been readily available in pediatric orthopaedic practice. Furthermore, the clinical value of genetic testing patients with LCPD is unclear. With the advance of next-generation sequencing (NGS) technology, genetic testing has become clinically available as a lab test...
April 23, 2024: Journal of Pediatric Orthopedics
https://read.qxmd.com/read/38651433/the-effect-of-sex-and-different-repetition-maximums-on-kinematics-and-surface-electromyography-in-the-last-repetition-of-the-barbell-back-squat
#28
JOURNAL ARTICLE
Andreas Hegdahl Gundersen, Hallvard Nygaard Falch, Andrea Bao Fredriksen, Roland van den Tillaar
During the ascent phase of a maximal barbell back squat after an initial acceleration, a deceleration region occurs as the result of different biomechanical factors. This is known as the sticking region. However, whether this region is similar in the last repetition of different repetition maximums and if sex has an impact on biomechanics of this region are not known. Therefore, this study investigated the effect of sex (men/women) and repetition maximum (1-, 3-, 6-, and 10RM) on kinematics and surface electromyography around the sticking region...
April 18, 2024: Journal of Functional Morphology and Kinesiology
https://read.qxmd.com/read/38651431/does-pelvic-tilt-angle-influence-the-isokinetic-strength-of-the-hip-and-knee-flexors-and-extensors
#29
JOURNAL ARTICLE
Eleftherios Kellis, Athanasios Konstantopoulos, Georgios Salonikios, Athanasios Ellinoudis
The purpose of this study was to examine the effect of pelvic tilt angle on maximum hip and knee muscles' strength and antagonist/agonist strength ratios. Twenty-one young males and females performed maximum isokinetic concentric knee extension-flexion and hip extension-flexion efforts at 60°·s-1 , 120°·s-1 , and 180°·s-1 from three positions: anterior, neutral, and posterior pelvic tilt. Peak torques and knee flexor-to-extensor and hip flexor-to-extensor torque ratios were analyzed...
April 12, 2024: Journal of Functional Morphology and Kinesiology
https://read.qxmd.com/read/38651421/assessing-the-effects-and-challenges-of-total-hip-arthroplasty-before-pregnancy-and-childbirth-a-systematic-review
#30
REVIEW
Athanasios Galanis, Stefania Dimopoulou, Panagiotis Karampinas, Elias Vasiliadis, Angelos Kaspiris, Evangelos Sakellariou, Christos Vlachos, Michail Vavourakis, Eftychios Papagrigorakis, Vasileios Marougklianis, Georgios Tsalimas, Dimitrios Zachariou, Christos Patilas, Iordanis Varsamos, Ioannis Kolovos, John Vlamis
Total hip arthroplasty is indubitably one of the most performed operations worldwide. On the other hand, especially in the western world, the average age that women get pregnant has raised confoundedly. Consequently, a steadily increasing number of women become pregnant after they had hip arthroplasty surgery, with copious potential implications. The amount of knowledge on this particular field is considered inadequate in the existing literature. This paper aims to augment clinicians understanding surrounding this topic...
April 4, 2024: Journal of Functional Morphology and Kinesiology
https://read.qxmd.com/read/38651328/exploring-the-relationship-between-lower-limb-strength-strength-asymmetries-and-curvilinear-sprint-performance-findings-from-a-pilot-study
#31
JOURNAL ARTICLE
Matic Sašek, Nejc Šarabon, Darjan Smajla
Team sports involve various sprinting actions, including curvilinear sprints, yet their neuromuscular factors have been understudied. The aim of this cross-sectional study was to investigate the relationship between lower limb muscle strength, strength asymmetries, linear sprint and curvilinear sprint performance. At two visits 12 male (age: 24.8 ± 4.7 years, height: 1.82 ± 0.06 m, body mass: 80 ± 6.58 kg) and 6 female (age: 20.8 ± 1...
2024: Science Progress
https://read.qxmd.com/read/38651227/comprehensive-guidance-for-the-prevention-of-periprosthetic-joint-infection-after-total-joint-arthroplasty-and-pitfalls-in-the-prevention
#32
REVIEW
Javad Parvizi, Yonghan Cha, Emanuele Chisari, Kangbaek Kim, Kyung-Hoi Koo
Total joint arthroplasty (TJA) is a surgical procedure, in which parts of damaged joints are removed and replaced with a prosthesis. The main indication of TJA is osteoarthritis, and the volume of TJA is rising annually along with the increase of aged population. Hip and knee are the most common joints, in which TJAs are performed. The TJA prosthesis is composed of metal, plastic, or ceramic device. Even though TJA is the most successful treatment for end-stage osteoarthritis, it is associated with various complications, and periprosthetic joint infection (PJI) is the most serious complication after TJA...
April 22, 2024: Journal of Korean Medical Science
https://read.qxmd.com/read/38650103/porcine-computational-modeling-to-investigate-developmental-dysplasia-of-the-hip
#33
JOURNAL ARTICLE
Chia-Yu Yu, Erin M Mannen, Trevor J Lujan, Gunes Uzer, Vidyadhar Upasani, Eric W Edmonds, Clare K Fitzpatrick
While it is well-established that early detection and initiation of treatment of developmental dysplasia of the hip (DDH) is crucial to successful clinical outcomes, research on the mechanics of the hip joint during healthy and pathological hip development in infants is limited. Quantification of mechanical behavior in both the healthy and dysplastic developing joints may provide insight into the causes of DDH and facilitate innovation in treatment options. In this study, subject-specific three-dimensional finite element models of two pigs were developed: one healthy pig and one pig with induced dysplasia in the right hindlimb...
April 22, 2024: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://read.qxmd.com/read/38649923/bilateral-intertrochanteric-fractures-in-an-elderly-patient-following-high-energy-trauma-a-case-report
#34
JOURNAL ARTICLE
Zhengjie Tang, Qingshu Wu, Pan Li, Xing Wei
BACKGROUND: Cases of bilateral hip fractures are rare, and even more so are cases of bilateral intertrochanteric fractures. Common causes include trauma, internal diseases, and primary or secondary bone diseases. We report a case of bilateral intertrochanteric fractures in an elderly patient following a severe car accident, a scenario not extensively reported in existing literature. CASE PRESENTATION: We report on an 84-year-old male who suffered severe trauma from a car accident, resulting in multiple injuries and shock state, with pain and limited mobility in both hip joints...
April 22, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38649919/is-ai-3d-printed-psi-an-accurate-option-for-patients-with-developmental-dysplasia-of-the-hip-undergoing-tha
#35
JOURNAL ARTICLE
Han Zheng, Eryou Feng, Yao Xiao, Xingyu Liu, Tianyu Lai, Zhibiao Xu, Jingqiao Chen, Shiwei Xie, Feitai Lin, Yiling Zhang
BACKGROUND: In traditional surgical procedures, significant discrepancies are often observed between the pre-planned templated implant sizes and the actual sizes used, particularly in patients with congenital hip dysplasia. These discrepancies arise not only in preoperative planning but also in the precision of implant placement, especially concerning the acetabular component. Our study aims to enhance the accuracy of implant placement during Total Hip Arthroplasty (THA) by integrating AI-enhanced preoperative planning with Patient-Specific Instrumentation (PSI)...
April 22, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38649911/eligibility-for-knee-arthroplasty-is-associated-with-increased-risk-of-acquired-hallux-valgus-a-mendelian-randomized-study
#36
JOURNAL ARTICLE
Zhijun Li, Zhengxuan Liu, Wei Shi, Xinyu Liang, Chunlei Xu, Kai Zhang, Hui Li, Huafeng Zhang
OBJECTIVE: Clinically, it has been found that patients undergoing knee replacement have a high incidence of concomitant hallux valgus. In this study, we analyzed whether patients with osteoarthritis who underwent surgery and those patient who did not have surgery had an increased risk of hallux valgus by Mendelian randomization and performed reverse causal analysis. DESIGN: Genomewide association study (GWAS) data for osteoarthritis, categorized by knee arthritis with joint replacement, knee arthritis without joint replacement, hip arthritis with joint replacement, and hip arthritis without joint replacement...
April 22, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38649874/15-year-survivorship-of-a-unique-dual-modular-femoral-stem-in-primary-hip-arthroplasty
#37
JOURNAL ARTICLE
David F Scott, Kade Eppich, Edin Mehić, Celeste Gray, Crystal Lederhos Smith, Michael Johnston
BACKGROUND: Hip offset, version, and length are interdependent femoral variables which determine stability and leg length. Balancing these competing variables remains a core challenge in hip arthroplasty. The potential benefits of modular femoral stems have been overshadowed by higher rates of failure. The objective of this study was to assess the survivorship of a unique dual-modular femoral stem at an average 15-year follow-up period. METHODS: The records of all patients with osteoarthritis who underwent primary total hip arthroplasty with this device between 2004-2009 were reviewed...
April 22, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38649830/prediction-of-walking-speed-one-year-following-hip-fracture-based-on-pre-fracture-assessments-of-mobility-and-physical-activity
#38
JOURNAL ARTICLE
Kristi Elisabeth Heiberg, Monica Beckmann, Vigdis Bruun-Olsen
BACKGROUND: Older people with hip fracture are often medically frail, and many do not regain their walking ability and level of physical activity. The aim of this study was to examine the relationship between pre-fracture recalled mobility, fear of falling, physical activity, walking habits and walking speed one year after hip fracture. METHODS: The study had a longitudinal design. Measurements were performed 3-5 days postoperatively (baseline) and at one year after the hip fracture...
April 22, 2024: BMC Geriatrics
https://read.qxmd.com/read/38649666/characteristics-of-different-obesity-metabolic-indexes-and-their-correlation-with-insulin-resistance-in-patients-with-polycystic-ovary-syndrome
#39
JOURNAL ARTICLE
Yaru Feng, Mengying Li, Xue Li, Qingtao Tang, Xiaoyan Li, Xia Ji, Wenyan Tian, Huiying Zhang
This study is aimed to investigate the characteristics of different obesity metabolic indexes [body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), cardiometabolic index (CMI), body roundness index (BRI), visceral adiposity index (VAI), and lipid aggregation products (LAP)] and their correlation with insulin resistance (IR) in patients with polycystic ovary syndrome (PCOS). The study was conducted on 140 subjects with PCOS and 133 control subjects aged 18-44 years...
April 22, 2024: Reproductive Sciences
https://read.qxmd.com/read/38649534/barriers-and-facilitators-to-implementation-of-an-exercise-and-education-programme-for-osteoarthritis-a-qualitative-study-using-the-consolidated-framework-for-implementation-research
#40
JOURNAL ARTICLE
Avantika Bhardwaj, Christine FitzGerald, Margaret Graham, Anne MacFarlane, Norelee Kennedy, Clodagh M Toomey
Targeted efforts to better understand the barriers and facilitators of stakeholders and healthcare settings to implementation of exercise and education self-management programmes for osteoarthritis (OA) are needed. This study aimed to explore the barriers and facilitators to the implementation of Good Life with osteoArthritis in Denmark (GLA:D), a supervised group guideline-based OA programme, across Irish public and private healthcare settings. Interviews with 10 physiotherapists (PTs; 8 public) and 9 people with hip and knee OA (PwOA; 4 public) were coded by the Consolidated Framework for Implementation Research (CFIR) constructs in a case memo (summary, rationale, quotes)...
April 22, 2024: Rheumatology International
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