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Sub arachnoid haemorrhage

Allan Hall, Roddy O'Kane
BACKGROUND: Subarachnoid hemorrhage (SAH) is managed across the full spectrum of healthcare, from clinical diagnosis to management of the hemorrhage and associated complications. Knowledge of the pathogenesis and pathophysiology of SAH is widely known; however, a full understanding of the underlying molecular, cellular, and circulatory dynamics has still to be achieved. Intracranial complications including delayed ischemic neurologic deficit (vasospasm), rebleed, and hydrocephalus form the targets for initial management...
January 2018: World Neurosurgery
J J P Buitendag, V Y Kong, J L Bruce, G L Laing, D L Clarke, P Brysiewicz
OBJECTIVES: This retrospective review of a prospectively entered and maintained hybrid electronic trauma registry was intended to develop a comprehensive overview of traumatic brain injury (TBI) in children and adolescents and to compare it with previous audits from our local environment and from other developing world centres. All TBI patients admitted to hospital were included in this study. We reviewed the age, gender, outcomes, radiological findings and treatment of the patients. METHODS: All patients aged ≤18 years old who were admitted by the Pietermaritzburg Metropolitan Trauma Service (PMTS) with TBI between December 2012 and December 2016 were included in this audit...
August 25, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
Jennifer Massey
PRES is a neurological syndrome characterised by reversible subcortical vasogenic brain oedema in patients with acute neurological signs and symptoms. It occurs in the context of fluctuations in blood pressure, renal failure, autoimmune disorders, eclamptic syndromes and with use of cytotoxic drugs. We present the case of a 60year old female with advanced bowel cancer who was admitted with seizures and sub-arachnoid haemorrhage, with radiographic features of PRES, shortly after receiving bevacizumab (Avastin), a VEGF-inhibitor...
June 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Yaseen Rauf, Usman Tariq Siddiqui, Gohar Javed
OBJECTIVE: To compare complications of cerebral angiography among patients with and without subarachnoid haemorrhage. METHODS: This retrospective study was conducted at the Aga Khan University Hospital, Karachi, and comprised records of patients undergoing inpatient therapeutic and diagnostic cerebral angiographies from 2001 to 2010. The patients were divided into subarachnoid and non-subarachnoid haemorrhage groups. During the study period no modifications were made to the operational protocol and all patients were subjected to the same procedure and prophylactic care...
January 2017: JPMA. the Journal of the Pakistan Medical Association
James A Lee, Laurence A G Marshman, Corey S Moran, Leslie Kuma, Eric P Guazzo, David S Anderson, Jonathan Golledge
Prior studies, using systemic hypertension and elastase infusion, have induced cerebral aneurysm (CA) formation in mice. However, the CAs induced were rapidly formed, relatively large, and often ruptured. These features are not completely representative of human CAs. We set out to develop a mouse model representative of the early pathological features of human CA. Twenty male C57/BL6 mice were placed in a stereotactic frame. Low dose elastase solution (2μl/min) was manually injected into the right basal cistern...
December 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Nayomi Shermila Jayasinghe, Eranga Thalagala, Milanka Wattegama, Kanapathipillai Thirumavalavan
BACKGROUND: Neurological manifestations in dengue fever occur in <1 % of the patients and known to be due to multisystem dysfunction secondary to vascular leakage. Occurrence of wide spread cerebral haemorrhages with subdural hematoma during the leakage phase without profound thrombocytopenia and occurrence of cranial diabetes insipidus are extremely rare and had not been reported in published literature earlier, thus we report the first case. CASE PRESENTATION: A 24 year old previously healthy lady was admitted on third day of fever with thrombocytopenia...
May 10, 2016: BMC Research Notes
Federica Montagnese, Francesca Granata, Olimpia Musumeci, Carmelo Rodolico, Stefania Mondello, Emanuele Barca, Maria Cucinotta, Anna Ciranni, Marcello Longo, Antonio Toscano
BACKGROUND AND OBJECTIVES: Pompe disease is a rare metabolic disorder due to lysosomal alpha-glucosidase (GAA) deficiency. It is considered as a multi-systemic disease since, although glycogen accumulation is largely prominent in heart, skeletal and respiratory muscles, other organs can also be affected. As regards the vascular system, few reports have documented cerebrovascular malformations in Pompe patients. The aim of this study was to define the presence and type of intracranial arterial abnormalities in a cohort of late onset Pompe disease (LOPD) patients...
May 2016: Journal of Inherited Metabolic Disease
Masoud Hatefi, Shirzad Azhary, Hussein Naebaghaee, Hasan Reza Mohamadi, Molouk Jaafarpour
BACKGROUND AND AIMS: SAH (Sub Arachnoid Haemorrhage) is a life threatening that is associated with complications such as vasospasm and shunt-dependent hydrocephalus. The purpose of this study was to assess the effect of FLT (Fenestration of Lamina Terminalis) on the incidence of vasospasm and shunt-dependent hydrocephalus in ACoA (Anterior Communicating Artery) aneurismal in SAH. MATERIALS AND METHODS: The data of 50 ruptured ACoA aneurism patients were selected during the year 2001-2009 admitted to Imam Hussein hospital, Tehran, IR...
July 2015: Journal of Clinical and Diagnostic Research: JCDR
Margherita Murgo, Kwendy Cavanagh, Simon Latham
BACKGROUND: Subarachnoid haemorrhage (SAH) is commonly a devastating injury with long lasting physical and psychosocial consequences for survivors. Support after hospital discharge through chronic care services for this patient group is limited. This study aimed to measure Health Related Quality of Life (HRQoL) and needs of survivors after discharge from hospital. METHODS: A population of patients that were diagnosed with SAH were contacted, up to 2 years post discharge, to participate in a postal survey including the Short Stroke Specific Quality of Life Scale (SSQoL-12), a service utilisation questionnaire and attitudes towards participating in a support group...
August 2016: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
P Harrow, H Kwok, G Parkes, P Premchand
INTRODUCTION: Leucocytapheresis, the extracorporeal removal of leucocytes from patient's blood, has conflicting evidence of benefit in ulcerative colitis (UC). Numerous studies have recorded short term clinical remission rates while few have examined the long term end-points of colectomy, death and steroid free remission. Queen's Hospital, Romford is one of the largest centres performing leucoytapheresis in the UK. Here we present a retrospective case series of patients treated with the Adacolumn® leucocytapheresis filter column for UC between 2008 and 2012, designed to assess these long term end-points with follow-up to June 2013...
June 2014: Gut
Dennis J Nieuwkamp, Ale Algra, Birgitta K Velthuis, Gabriël J E Rinkel
BACKGROUND AND AIM: Risk factors for aneurysmal sub-arachnoid haemorrhage can be divided into environmental and inherited factors; the latter being presumed more important in young patients. We explored in young sub-arachnoid haemorrhage patients whether risk-factor profiles influence clinical and radiological characteristics of aneurysms and sub-arachnoid haemorrhage. METHODS: From the 2139 aneurysmal sub-arachnoid haemorrhage patients who had been entered in our prospectively collected database between January 1997 and August 2012, we retrieved data on young (18-40 years) aneurysmal sub-arachnoid haemorrhage patients and compared those with smoking or hypertension (atherogenic risk factors) with those without...
December 2014: International Journal of Stroke: Official Journal of the International Stroke Society
R D Bharath, M K Vasudev, P N Jayakumar, G Goel, J M E Kovoor, S Ravishankar, K Thennarasu
Over the past decade preventive endovascular treatment is increasingly being considered for intracranial aneurysms irrespective of whether ruptured or unruptured. Few studies have dealt with in-vivo characteristics of intracranial aneurysms. We compare the angiographic morphology of ruptured and unruptured intracranial aneurysms using short interval serial DSA. 37 patients with intracranial aneurysms and who underwent at least two digital subtraction angiograms were included in the study. Based on the clinical presentation there were two subgroups of patients, Group A patients presenting acutely with Sub arachnoid haemorrhage (SAH) and Group B patients who had no clinical or imaging features suggestive of bleed...
December 14, 2009: Neuroradiology Journal
A A Khan, J D Shand Smith, M A Kirkman, F J Robertson, K Wong, C Dott, J P Grieve, L D Watkins, N D Kitchen
BACKGROUND: Angiogram negative sub-arachnoid haemorrhage (SAH) is generally considered to have a more benign course than SAH of known cause. There is also variability from centre to centre as to what proportion of angiogram negative SAH patients undergo repeat Digital Subtraction Angiography (DSA). We performed a retrospective study looking at the last four years' of SAH patients at our institution in order to ascertain the clinical course, the nature and results of repeat imaging. METHODS: Retrospective analysis of clinical records and imaging of all patients presenting to our institution with non-traumatic SAH between April 2008 and February 2012 was performed...
August 2013: Clinical Neurology and Neurosurgery
H R Haynes, A Visca, S Renowden, G Malcolm
A case of thrombus formation occurring within a dilation of the dural venous sinuses following aneurysmal sub-arachnoid haemorrhage is presented. Acute neurological deterioration accompanied propagation of the thrombus. The patient was anticoagulated on day 5 post-SAH with no haemorrhagic complications and made a full recovery. The optimum time to commence anticoagulation is not clear and is discussed.
August 2013: British Journal of Neurosurgery
Beom Joon Kim, Seung-Hoon Lee, Wi-Sun Ryu, Chi Kyung Kim, Jong-Won Chung, Dohoung Kim, Hong-Kyun Park, Hee-Joon Bae, Byung-Joo Park, Byung-Woo Yoon
BACKGROUND: Adverse effect of excessive work on health has been suggested previously, but it was not documented in cerebrovascular diseases. AIM: The authors investigated whether excessive working conditions would associate with increased risk of haemorrhagic stroke. METHODS: A nationwide matched case-control study database, which contains 940 cases of incident haemorrhagic stroke (498 intracerebral haemorrhages and 442 sub-arachnoid haemorrhages) with 1880 gender- and age- (± 5-year) matched controls, was analysed...
October 2013: International Journal of Stroke: Official Journal of the International Stroke Society
Maria Emília Rodrigues de Oliveira Thais, Gisele Cavallazzi, Douglas Afonso Formolo, Lucas D'Ávila de Castro, Roseli Schmoeller, Ricardo Guarnieri, Marcelo Liborio Schwarzbold, Alexandre Paim Diaz, Alexandre Hohl, Rui D S Prediger, Maria Joana Mader, Marcelo Neves Linhares, Angelica Staniloiu, Hans J Markowitsch, Roger Walz
OBJECTIVES: Traumatic brain injury (TBI) is a main cause of mortality and morbidity. Association studies between hospitalization variables and cognitive impairment after TBI are frequently retrospective, including non-consecutive patients showing variable degrees of TBI severity, and poor management of missing (drop out) cases. METHODS: We assessed prospectively the demographic and hospitalization variables of 234 consecutive patients with severe TBI (admission Glasgow Coma Scale [GCS] ≤8) and determined their independent association with cognitive performance in a representative sample (n = 46) of surviving patients (n = 172) evaluated 3 (±1...
March 2014: Journal of Neuropsychology
Emanuele Cigna, Michele Maruccia, Benedetta Fanelli, Nicolò Scuderi
Use of botulinum toxin is expanding as the clinical studies demonstrate new potential therapeutic applications. In rehabilitation, botulinum toxin is above all used as adjunct therapy for the treatment of spasticity, but it may prove useful for other atypical clinical situations. A 17-year-old man had a sub-arachnoid haemorrhage following the rupture of cerebral aneurism. The patient presented gluteus maximus and medius bilaterally spasticity that produced a chronic lesion in the intergluteal cleft, a flexed wrist and a flexed elbow...
August 2014: International Wound Journal
Joung-Ho Rha, Jaseong Koo, Ki Hyun Cho, Eung-Gyu Kim, Gun Sei Oh, Se Jin Lee, Jae Kwan Cha, Jin-Jeong Oh, Gyoung-Rye Ham, Hyun-Soo Seo, Jong S Kim
BACKGROUND: Despite increasing socio-economic burden of stroke, few studies have investigated the costs associated with the stroke care in Korea. We estimated the two-year direct medical costs associated with stroke. METHODS: This was a multi-centre, incidence-based, retrospective observational study. We examined the records of all adult patients who were admitted in eight large hospitals throughout Korea due to acute stroke [I60: sub-arachnoid haemorrhage; I61: intracerebral haemorrhage; I62: other nontraumatic haemorrhage; I63: cerebral infarction, by The International Statistical Classification of Diseases and Related Health Problems (ICD)-10] between 1 November and 31 December 2006...
April 2013: International Journal of Stroke: Official Journal of the International Stroke Society
S B Campbell
No abstract text is available yet for this article.
July 1932: Ulster Medical Journal
Sadaf Nasir, Manzar Hussain, Sikandar Ali Khan, Muhammad Ayub Mansoor, Salman Sharif
A 50 years old male was admitted with sub-arachnoid haemorrhage. Angiographic examination revealed an abnormal origin of the right vertebral artery from the right external carotid artery. Multiple variations in the origin of right vertebral artery have been reported in literatures. Anomalous origin of the right vertebral artery from the right external carotid artery has not been reported earlier.
March 2010: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
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