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https://www.readbyqxmd.com/read/28429165/the-use-of-rapid-test-quikread-go%C3%A2-strep-a-in-bacterial-pharyngotonsillitis-diagnosing-and-therapeutic-decisions
#1
E Stefaniuk, K Bosacka, M Wanke-Rytt, W Hryniewicz
Group A Streptococci (GAS) are the main causative agents of bacterial pharyngitis, which require antibiotic therapy. Rapid diagnostic tests detecting GAS combined with Centor/McIsaac score enable accurate differential diagnosis (viral vs. bacterial) and prompt commencement of targeted treatment. The aim of this study was to assess the specificity, sensitivity, PPV and NPV of QuikRead go® Strep A (Orion Diagnostica Oy, Finland) recommended for the detection of GAS in pharyngeal swabs. Quick diagnostic test results were compared with physical examination findings, Centor/McIsaac score and results of reference testing (conventional microbial cultures)...
April 21, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28426941/behavioral-deficits-and-neural-damage-of-caenorhabditis-elegans-induced-by-three-rare-earth-elements
#2
Tiantian Xu, Manke Zhang, Jiani Hu, Zihan Li, Taipu Wu, Jianing Bao, Siyu Wu, Lili Lei, Defu He
Rare earth elements (REEs) are widely used in industry, agriculture, medicine and daily life in recent years. However, environmental and health risks of REEs are still poorly understood. In this study, neurotoxicity of trichloride neodymium, praseodymium and scandium were evaluated using nematode Caenorhabditis elegans as the assay system. Median lethal concentrations (48 h) were 99.9, 157.2 and 106.4 mg/L for NdCl3, PrCl3 and ScCl3, respectively. Sublethal dose (10-30 mg/L) of these trichloride salts significantly inhibited body length of nematodes...
April 17, 2017: Chemosphere
https://www.readbyqxmd.com/read/28424896/maximum-tongue-pressure-is-associated-with-swallowing-dysfunction-in-als-patients
#3
Aya Hiraoka, Mineka Yoshikawa, Masahiro Nakamori, Naohisa Hosomi, Toshikazu Nagasaki, Takahiro Mori, Masaya Oda, Hirofumi Maruyama, Mitsuyoshi Yoshida, Yuishin Izumi, Masayasu Matsumoto, Kazuhiro Tsuga
Maximum tongue pressure (MTP) measurement is a convenient, less invasive assessment that has been developed to quantify tongue strength; however, it is unclear whether MTP is useful for the detection of swallowing disorders in amyotrophic lateral sclerosis (ALS) patients. The purpose of this study was to clarify the relationship between MTP and the characteristics of swallowing disorders on videofluorography and to determine the usefulness of tongue pressure measurement for the assessment of swallowing function in ALS patients...
April 19, 2017: Dysphagia
https://www.readbyqxmd.com/read/28424727/host-induced-silencing-of-two-pharyngeal-gland-genes-conferred-transcriptional-alteration-of-cell-wall-modifying-enzymes-of-meloidogyne-incognita-vis-%C3%A3-vis-perturbed-nematode-infectivity-in-eggplant
#4
Tagginahalli N Shivakumara, Sonam Chaudhary, Divya Kamaraju, Tushar K Dutta, Pradeep K Papolu, Prakash Banakar, Rohini Sreevathsa, Bhupinder Singh, K M Manjaiah, Uma Rao
The complex parasitic strategy of Meloidogyne incognita appears to involve simultaneous expression of its pharyngeal gland-specific effector genes in order to colonize the host plants. Research reports related to effector crosstalk in phytonematodes for successful parasitism of the host tissue is yet underexplored. In view of this, we have used in planta effector screening approach to understand the possible interaction of pioneer genes (msp-18 and msp-20, putatively involved in late and early stage of M. incognita parasitism, respectively) with other unrelated effectors such as cell-wall modifying enzymes (CWMEs) in M...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28422004/performance-of-influenza-case-definitions-for-influenza-community-surveillance-based-on-the-french-influenza-surveillance-network-grog-2009-2014
#5
Jean-Sebastien Casalegno, Daniel Eibach, Martine Valette, Vincent Enouf, Isabelle Daviaud, Sylvie Behillil, Astrid Vabret, Jean Claude Soulary, Mehdi Benchaib, Jean Marie Cohen, Sylvie van der Werf, Anne Mosnier, Bruno Lina
International case definitions recommended by the Centers for Disease Control and Prevention (CDC), the European Centre for Disease Prevention and Control (ECDC), and the World Health Organization (WHO) are commonly used for influenza surveillance. We evaluated clinical factors associated with the laboratory-confirmed diagnosis of influenza and the performance of these influenza case definitions by using a complete dataset of 14,994 patients with acute respiratory infection (ARI) from whom a specimen was collected between August 2009 and April 2014 by the Groupes Régionaux d'Observation de la Grippe (GROG), a French national influenza surveillance network...
April 6, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28419557/usefulness-of-the-valsalva-maneuver-without-a-mouthpiece-to-observe-the-hypopharynx-using-transoral-endoscopy
#6
Yasushi Yamasaki, Ryu Ishihara, Kenta Hamada
Transoral endoscopy with narrow band imaging is useful for early detection of pharyngeal cancer.(1) The postcricoid area and the posterior wall of the hypopharynx, however, are still difficult to observe because they're anatomically closed.(2) Although the Valsalva maneuver with transnasal endoscopy has been reportedly useful for opening the closed area,(3) it is difficult with transoral endoscopy. This article is protected by copyright. All rights reserved.
April 17, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28419320/therapeutic-cpap-level-predicts-upper-airway-collapsibility-in-patients-with-obstructive-sleep-apnea-therapeutic-cpap-predicts-upper-airway-collapsibility
#7
Shane A Landry, Simon A Joosten, Danny J Eckert, Amy S Jordan, Scott A Sands, David P White, Atul Malhotra, Andrew Wellman, Garun S Hamilton, Bradley A Edwards
Study Objectives: Upper airway collapsibility is a key determinant of obstructive sleep apnea (OSA) which can influence the efficacy of certain non-CPAP treatment for OSA. However, there is no simple way to measure this variable clinically. The present study aimed to develop a clinically implementable tool to evaluate the collapsibility of a patient's upper airway. Methods: Collapsibility, as characterized by the passive pharyngeal critical closing pressure (Pcrit), was measured in 46 patients with OSA...
April 13, 2017: Sleep
https://www.readbyqxmd.com/read/28418700/three-dimensional-analysis-of-upper-airway-morphology-in-skeletal-class-iii-patients-with-and-without-mandibular-asymmetry
#8
Xi Wen, Xiyu Wang, Shuqi Qin, Lorenzo Franchi, Yan Gu
OBJECTIVE: To compare the three-dimensional (3D) morphology of the upper airway in skeletal Class III patients with and without mandibular asymmetry and to investigate the possible underlying correlations between the morphology of the upper airway and mandibular deviation. MATERIALS AND METHODS: Cone-beam computed tomography images of 54 subjects with skeletal Class III malocclusion (ANB angle ≤ 0.4°, Wits ≤ -5.5°) were taken and 3D upper airway models were reconstructed using Dolphin 3D software...
April 18, 2017: Angle Orthodontist
https://www.readbyqxmd.com/read/28418347/difficult-cases-of-odontogenic-deep-neck-infections-a-report-of-three-patients
#9
Onur İsmi, Mesut Yeşilova, Cengiz Özcan, Yusuf Vayisoğlu, Kemal Görür
BACKGROUND: Deep neck infections are important otolaryngologic emergencies due to serious complications and the risk of airway compromise, which can lead to mortality. Although the most common causes among pediatric patients are tonsillitis and pharyngeal infections, odontogenic infections are an important cause in adults. CASE REPORT: We present three patients with multiple deep neck space abscess formation due to odontogenic infection. Two of them required tracheotomy due to airway compromise, and one had mediastinitis...
April 5, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28417904/zebrafish-as-an-alternative-vertebrate-model-for-investigating-developmental-toxicity-the-triadimefon-example
#10
Maria Zoupa, Kyriaki Machera
Triadimefon is a widely used triazole fungicide known to cause severe developmental defects in several model organisms and in humans. The present study evaluated in detail the developmental effects seen in zebrafish embryos exposed to triadimefon, confirmed and expanded upon previous phenotypic findings and compared them to those observed in other traditional animal models. In order to do this, we exposed embryos to 2 and 4 µg/mL triadimefon and evaluated growth until 120 h post-fertilization (hpf) through gross morphology examination...
April 12, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28417671/the-use-of-noninvasive-positive-pressure-ventilation-following-pediatric-tonsillectomy
#11
Adva Buzi, Orly M Coblens, Michael MacGillivray, Lisa Elden
Objective To determine the risks of bleeding and other complications in pediatric patients who require noninvasive positive pressure ventilation (PPV) in the immediate posttonsillectomy period. Study Design Case series with chart review. Setting Single tertiary pediatric hospital. Subjects and Methods Sixty-nine patients who had undergone tonsillectomy from July 2007 through December 2013 and required postoperative PPV were reviewed. Data collected included age, sex, medical history, preoperative polysomnogram parameters, length of use and type of noninvasive ventilatory support, and postoperative complications...
April 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28416844/clinical-characteristics-of-neurogenic-dysphagia-in-adult-patients-with-chiari-malformation-type-i
#12
T Yu, J Li, K Wang, Y Ge, A C Jiang, L P Duan, Z Y Wang
OBJECTIVE: To investigate changes of swallowing function and associated symptoms in Chiari malformation typeI (CMI) patients with and without dysphagia by the analysis of their clinical and high-resolution manometry (HRM) parameters. METHODS: A total of 42 patients diagnosed with symptomatic CMI without atlantoaxial dislocations which were confirmed by clinical manifestations and magnetic resonance imaging (MRI) findings between January 2010 and July 2015 at Peking University Third Hospital were included in this study...
April 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28414873/influence-of-pharyngeal-airway-respiration-pressure-on-class-ii-mandibular-retrusion-in-children-a-computational-fluid-dynamics-study-of-inspiration-and-expiration
#13
T Iwasaki, H Sato, H Suga, Y Takemoto, E Inada, I Saitoh, K Kakuno, R Kanomi, Y Yamasaki
OBJECTIVES: To examine the influence of negative pressure of the pharyngeal airway on mandibular retraction during inspiration in children with nasal obstruction using the computational fluid dynamics (CFD) method. SETTING AND SAMPLE POPULATION: Sixty-two children were divided into Classes I, II (mandibular retrusion) and III (mandibular protrusion) malocclusion groups. MATERIAL AND METHODS: Cone-beam computed tomography data were used to reconstruct three-dimensional shapes of the nasal and pharyngeal airways...
May 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28414663/not-another-acs-rule-out
#14
S Preston, R Nelson, M Watts, D Smith, T Dewenter, D Spruill
CASE: A 50 year old African-American woman with diabetes, hypertension, and hyperlipidemia presented with progressively worsening retro-sternal chest pain, exacerbated by activity and relieved by rest. She also endorsed a thirty-pound unintentional weight loss, and dysphagia. She was dysarthric with left-sided Bell's Palsy and a palpable left axillary lymph node. She had been evaluated at several hospitals in the previous months for similar typical chest pain. Her troponin values were normal, and an EKG showed T-wave inversions in leads I and aVL...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28413282/comparison-of-success-of-tracheal-intubation-using-macintosh-laryngoscope-assisted-bonfils-fiberscope-and-truview-video-laryngoscope-in-simulated-difficult-airway
#15
Bangaru Vivek, R Sripriya, Gayatri Mishra, M Ravishankar, S Parthasarathy
BACKGROUND AND AIMS: Restriction of head and neck movements prevents the alignment of the oral, pharyngeal, and laryngeal axes and increases the incidence of difficult tracheal intubation in patients with cervical spine fractures. Video laryngoscopes have gained an important role in the management of difficult intubation, especially in situations with limited head and neck movements. This study compares the success of intubation using Macintosh laryngoscope assisted Bonfils(®) fiberscope (ML-BF) with Truview(PCD) video laryngoscope (TV) in patients with simulated restricted head and neck movements...
January 2017: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/28412180/computational-fluid-dynamics-study-of-the-pharyngeal-airway-space-before-and-after-mandibular-setback-surgery-in-patients-with-mandibular-prognathism
#16
Y Yajima, M Oshima, T Iwai, H Kitajima, S Omura, I Tohnai
The purpose of this study was to investigate the relationship between the pressure drop in the pharyngeal airway space (ΔPPAS) and the minimum cross-sectional area (minCSA) of the pharyngeal airway before and after mandibular setback surgery using computational fluid dynamics, in order to prevent iatrogenic obstructive sleep apnoea. Eleven patients with mandibular prognathism underwent bilateral sagittal split osteotomy for mandibular setback. Three-dimensional models of the upper airway were reconstructed from preoperative and postoperative computed tomography images, and simulations were performed using computational fluid dynamics...
April 12, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28412164/diagnosis-and-management-of-oropharyngeal-dysphagia-among-older-persons-state-of-the-art
#17
REVIEW
Omar Ortega, Alberto Martín, Pere Clavé
Oropharyngeal dysphagia (OD) is a condition recognized by the World Health Organization and defined as the difficulty or inability to move a bolus safely and effectively from the oral cavity to the esophagus, and can include aspirations, choking, and residue. OD is pandemic among different phenotypes of older people, affecting between 27% and 91% of the population 70 years or older. Although OD can be diagnosed by well-defined clinical methods and complementary explorations, in the clinical setting OD is seldom systematically screened and treated, and awareness among the medical/geriatric community is scarce...
April 12, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28409851/response-to-a-combination-of-oxygen-and-a-hypnotic-as-treatment-for-obstructive-sleep-apnoea-is-predicted-by-a-patient-s-therapeutic-cpap-requirement
#18
Shane A Landry, Simon A Joosten, Scott A Sands, David P White, Atul Malhotra, Andrew Wellman, Garun S Hamilton, Bradley A Edwards
BACKGROUND AND OBJECTIVE: Upper airway collapsibility predicts the response to several non-continuous positive airway pressure (CPAP) interventions for obstructive sleep apnoea (OSA). Measures of upper airway collapsibility cannot be easily performed in a clinical context; however, a patient's therapeutic CPAP requirement may serve as a surrogate measure of collapsibility. The present work aimed to compare the predictive use of CPAP level with detailed physiological measures of collapsibility...
April 13, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28405393/lung-anatomy-and-histology-of-the-extant-coelacanth-shed-light-on-the-loss-of-air-breathing-during-deep-water-adaptation-in-actinistians
#19
Camila Cupello, François J Meunier, Marc Herbin, Gaël Clément, Paulo M Brito
Lungs are specialized organs originated from the posterior pharyngeal cavity and considered as plesiomorphic for osteichthyans, as they are found in extant basal actinopterygians (i.e. Polypterus) and in all major groups of extant sarcopterygians. The presence of a vestigial lung in adult stages of the extant coelacanth Latimeria chalumnae is the result of allometric growth during ontogeny, in relation with long-time adaptation to deep water. Here, we present the first detailed histological and anatomical description of the lung of Latimeria chalumnae, providing new insights into its arrested differentiation in an air-breathing complex, mainly represented by the absence of pneumocytes and of compartmentalization in the latest ontogenetic stages...
March 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28403114/prevalence-of-inappropriate-antibiotic-prescriptions-after-the-great-east-japan-earthquake-2011
#20
Kentaro Iwata, Takahiko Fukuchi, Midori Hirai, Kenichi Yoshimura, Yasuhiro Kanatani
Few studies have investigated the appropriateness of antibiotic use in postdisaster settings. We retrospectively evaluated clinical databases on health care delivered at clinics near shelters set up after the Great East Japan Earthquake, 2011. We defined appropriate, acceptable, and inappropriate antibiotic use for each diagnostic category, by applying and adopting precedent studies and clinical guidelines. From March to July, 2011, a total of 23,704 clinic visits occurred at 98 shelters with 7934 residents...
April 2017: Medicine (Baltimore)
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