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https://www.readbyqxmd.com/read/29653106/assessment-of-nociception-and-pain-in-participants-with-unresponsive-or-minimally-conscious-state-after-acquired-brain-injury-the-relationship-between-the-coma-recovery-scale-revised-and-the-nociception-coma-scale-revised
#1
Camille Chatelle, Solveig L Hauger, Charlotte Martial, Frank Becker, Bernd Eifert, Dana Boering, Joseph T Giacino, Steven Laureys, Marianne Løvstad, Petra Maurer-Karattup
OBJECTIVE: Investigate the relationship between consciousness and nociceptive responsiveness (i.e., Nociception Coma Scale-Revised [NCS-R]), examine the suitability of the NCS-R for assessing nociception in participants with disorders of consciousness (DoC) and replicate previous findings on psychometric properties of the scale. DESIGN: We prospectively assessed consciousness with the Coma Recovery Scale-Revised (CRS-R). Responses during baseline, non-noxious and noxious stimulations were scored with the NCS-R, CRS-R oromotor and motor subscales...
April 10, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29628967/augmentation-of-respiratory-muscle-activities-in-preterm-infants-with-feeding-desaturation
#2
Dong Rak Kwon, Gi Young Park, Ji Eun Jeong, Woo Taek Kim, Eun Joo Lee
Purpose: Frequent desaturation due to immature incoordination of suck-swallow-breathing in preterm infants can influence multiple organs such as the heart, lungs, and brain, which can then affect growth and development. Most notably in preterm infants, feeding desaturation may even affect pulmonary function during gavage feeding. Because respiratory muscle activities may reflect the work required during respiration, we evaluated the differences in these activities between full-term and preterm infants with feeding desaturation, and investigated the correlations with clinical variables...
March 2018: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/29594076/translation-cross-cultural-adaptation-validation-and-reliability-of-the-northwestern-dysphagia-patient-check-sheet-ndpcs-in-iran
#3
Jalal Bakhtiyari, Masoomeh Salmani, Reyhaneh Noruzi, Payam Sarraf, Ebrahim Barzegar, Majid Mirmohammadkhani
Introduction: Speech and language therapists (SLTs) require proper tools to detect dysphagia in the early stages. One of these screening tools is the Northwestern Dysphagia Patient Check Sheet (NDPCS). However, this tool needs to be adapted, validated, and shown to be reliable for the Persian culture. The aim of the present study was to report the validity and reliability of the Persian NDPCS (P-NDPCS). Materials and Methods: The NDPCS has 28 items and five sections...
March 2018: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29536651/neurobehavioral-features-in-individuals-with-kabuki-syndrome
#4
Cristina Caciolo, Paolo Alfieri, Giorgia Piccini, Maria Cristina Digilio, Francesca Romana Lepri, Marco Tartaglia, Deny Menghini, Stefano Vicari
BACKGROUND: Kabuki syndrome (KS) is a disorder characterized by multiple congenital anomalies affecting development and function of multiple systems. Over the years, researchers have attempted to characterize the neurobehavioral phenotype of KS in cohorts of patients enrolled on the basis of clinical assessment. The availability of molecular testing now allows for recruitment of patients with confirmed KS due to KMT2D and KDM6A. METHODS: The aims of the present study were to investigate the neuropsychological and behavioral profiles of individuals with molecularly confirmed diagnosis of KS, and determine the extent of heterogeneity occurring in these profiles between individuals with clinical diagnosis of KS with and without mutations in KMT2D...
March 13, 2018: Molecular Genetics & Genomic Medicine
https://www.readbyqxmd.com/read/29475807/the-occurrence-of-respiratory-events-in-young-subjects-with-a-frequent-rhythmic-masticatory-muscle-activity-a-pilot-study
#5
Akiko Tsujisaka, Shingo Haraki, Shigeru Nonoue, Akira Mikami, Hiroyoshi Adachi, Takahiro Mizumori, Hirofumi Yatani, Atsushi Yoshida, Takafumi Kato
PURPOSE: Concomitant occurrence of respiratory events can be often overlooked in the clinical practice of SB. This study assessed physiological characteristics of rhythmic masticatory muscle activity (RMMA) and concomitant respiratory events in young SB subjects asymptomatic to obstructive sleep apnea (OSA). METHODS: Twenty-two subjects (age: 24.1±1.9years; F 8: M 14; BMI: 20.2±1.9kg/m2 ) were polysomnographically diagnosed as moderate-severe SB. Sleep architecture, oromotor (RMMA and non-specific masseter activity [NSMA]) and apnea/hypopnea events were scored...
February 20, 2018: Journal of Prosthodontic Research
https://www.readbyqxmd.com/read/29362829/an-exploratory-investigation-of-the-effects-of-whole-head-vibration-on-jaw-movements
#6
Meg Simione, Jordan R Green
The perturbing effects of vibration applied to head and body structures are known to destabilize motor control and elicit corrective responses. Although such vibration response testing may be informative for identifying sensorimotor deficits, the effect of whole-head vibration has not been tested on oromotor control. The purpose of this study was to determine how jaw movements respond to the perturbing effects of whole-head vibration during jaw motor tasks. Ten healthy adults completed speech, chewing, and two syllable repetition tasks with and without whole-head vibration...
January 23, 2018: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29354572/association-of-post-extubation-dysphagia-with-tongue-weakness-and-somatosensory-disturbance-in-non-neurologic-critically-ill-patients
#7
Hee Seon Park, Jung Hoi Koo, Sun Hong Song
Objective: To prospectively assess the association between impoverished sensorimotor integration of the tongue and lips and post-extubation dysphagia (PED). Methods: This cross-sectional study included non-neurologic critically ill adult patients who required endotracheal intubation and underwent videofluoroscopic swallowing study (VFSS) between October and December 2016. Participants underwent evaluation for tongue and lip performance, and oral somatosensory function...
December 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29201831/an-infantile-case-of-sandhoff-disease-presenting-with-swallowing-difficulty
#8
Jae-Gun Moon, Min-A Shin, Hannah Pyo, Seong-Uk Choi, Hyun-Kyung Kim
Infants with Sandhoff disease typically appear normal until 3-6 months of age. As the disease progresses, they present with symptoms such as loss of motor skills, exaggerated startle response to loud noise, seizures, visual loss, and paralysis. We encountered a rare case of a 22-month-old girl with Sandhoff disease characterized by progressive motor weakness and dysphagia, who initially showed signs of aspiration at 20 months of age. The major problems related to dysphagia were oromotor dysfunction and abnormal feeding posture...
October 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29174050/phonological-working-memory-and-foxp2
#9
Katrin Schulze, Faraneh Vargha-Khadem, Mortimer Mishkin
The discovery and description of the affected members of the KE family (aKE) initiated research on how genes enable the unique human trait of speech and language. Many aspects of this genetic influence on speech-related cognitive mechanisms are still elusive, e.g. if and how cognitive processes not directly involved in speech production are affected. In the current study we investigated the effect of the FOXP2 mutation on Working Memory (WM). Half the members of the multigenerational KE family have an inherited speech-language disorder, characterised as a verbal and orofacial dyspraxia caused by a mutation of the FOXP2 gene...
January 8, 2018: Neuropsychologia
https://www.readbyqxmd.com/read/29109055/characterization-of-oromotor-and-limb-motor-dysfunction-in-the-dj1-model-of-parkinson-disease
#10
Katie M Yang, Katherine V Blue, Haleigh M Mulholland, Meghna P Kurup, Cynthia A Kelm-Nelson, Michelle R Ciucci
Parkinson disease (PD) is devastating to sensorimotor function that includes cranial/oromotor and limb motor deficits. However, the onset, progression, and neural correlates of PD-related dysfunctions are poorly understood. To address this gap, we used a genetic rat model of PD, DJ1 -/-, and hypothesized that motor deficits would manifest early in the disease process, be progressive in nature, and be related to pathologies in brainstem structures associated with sensorimotor function. The present study compares homozygous DJ1 -/- male rats to age-matched wild type controls...
February 26, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29066561/concerted-interneuron-activity-in-the-cerebellar-molecular-layer-during-rhythmic-oromotor-behaviors
#11
Guadalupe Astorga, Dongdong Li, Ludivine Therreau, Merouann Kassa, Alain Marty, Isabel Llano
Molecular layer interneurons (MLIs, stellate and basket cells) of the cerebellar cortex are linked together by chemical and electrical synapses and exert a potent feedforward inhibition on Purkinje cells. The functional role of MLIs during specific motor tasks is uncertain. Here, we used two-photon imaging to study the patterns of activity of neighboring individual MLIs in the Crus II region of awake female mice during two types of oromotor activity, licking and bruxing, using specific expression of the genetically encoded calcium indicator protein GCaMP6s...
November 22, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28960626/comparison-of-rhythmic-masticatory-muscle-activity-during-non-rapid-eye-movement-sleep-in-guinea-pigs-and-humans
#12
Takafumi Kato, Risa Toyota, Shingo Haraki, Hiroyuki Yano, Makoto Higashiyama, Yoshio Ueno, Hiroshi Yano, Fumihiko Sato, Hirofumi Yatani, Atsushi Yoshida
Rhythmic masticatory muscle activity can be a normal variant of oromotor activity, which can be exaggerated in patients with sleep bruxism. However, few studies have tested the possibility in naturally sleeping animals to study the neurophysiological mechanisms of rhythmic masticatory muscle activity. This study aimed to investigate the similarity of cortical, cardiac and electromyographic manifestations of rhythmic masticatory muscle activity occurring during non-rapid eye movement sleep between guinea pigs and human subjects...
September 27, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28828751/maturation-modulates-pharyngeal-stimulus-provoked-pharyngeal-and-respiratory-rhythms-in-human-infants
#13
Kathryn A Hasenstab, Swetha Sitaram, Ivan M Lang, Reza Shaker, Sudarshan R Jadcherla
Pharyngeal-provocation induced aerodigestive symptoms in infants remain an enigma. Sources of pharyngeal provocation can be anterograde as with feeding, and retrograde as in gastroesophageal reflux. We determined maturational and dose-response effects of targeted pharyngeal-stimulus on frequency, stability, and magnitude of pharyngeal and respiratory waveforms during multiple pharyngeal swallowing responses in preterm-born infants when they were of full-term postmenstrual age (PMA). Eighteen infants (11 male) were studied longitudinally at 39...
August 21, 2017: Dysphagia
https://www.readbyqxmd.com/read/28704690/joint-attention-and-oromotor-abilities-in-young-children-with-and-without-autism-spectrum-disorder
#14
Jennifer C Dalton, Elizabeth R Crais, Shelley L Velleman
PURPOSE: This study examined the relationship between joint attention ability and oromotor imitation skill in three groups of young children with and without Autism Spectrum Disorder using both nonverbal oral and verbal motor imitation tasks. Research questions addressed a) differences among joint attention and oromotor imitation abilities; b) the relationship between independently measured joint attention and oromotor imitation, both nonverbal oral and verbal motor; c) the relationships between joint attention and verbal motor imitation during interpersonal interaction; and d) the relationship between the sensory input demands (auditory, visual, and tactile) and oromotor imitation, both nonverbal oral and verbal motor...
July 1, 2017: Journal of Communication Disorders
https://www.readbyqxmd.com/read/28704379/fractionating-nonword-repetition-the-contributions-of-short-term-memory-and-oromotor-praxis-are-different
#15
Saloni Krishnan, Katherine J Alcock, Daniel Carey, Lina Bergström, Annette Karmiloff-Smith, Frederic Dick
The ability to reproduce novel words is a sensitive marker of language impairment across a variety of developmental disorders. Nonword repetition tasks are thought to reflect phonological short-term memory skills. Yet, when children hear and then utter a word for the first time, they must transform a novel speech signal into a series of coordinated, precisely timed oral movements. Little is known about how children's oromotor speed, planning and co-ordination abilities might influence their ability to repeat novel nonwords, beyond the influence of higher-level cognitive and linguistic skills...
2017: PloS One
https://www.readbyqxmd.com/read/28595097/neuropredictors-of-oromotor-feeding-impairment-in-12month-old-children
#16
Katherine Sanchez, Angela T Morgan, Justine M Slattery, Joy E Olsen, Katherine J Lee, Peter J Anderson, Deanne K Thompson, Lex W Doyle, Jeanie L Y Cheong, Alicia J Spittle
BACKGROUND: Feeding impairment is prevalent in children with neurodevelopmental issues. Neuroimaging and neurobehavioural outcomes at term are predictive of later neuromotor impairment, but it is unknown whether they predict feeding impairment. AIMS: To determine whether neurobehavior and brain magnetic resonance imaging (MRI) at term predict oromotor feeding at 12months in preterm and term-born children. STUDY DESIGN: Prospective cohort study...
August 2017: Early Human Development
https://www.readbyqxmd.com/read/28527575/coup-tf-genes-human-diseases-and-the-development-of-the-central-nervous-system-in-murine-models
#17
Xiong Yang, Su Feng, Ke Tang
COUP-TFI and -TFII are members of the steroid/thyroid nuclear receptor superfamily. Recent clinical studies reveal that COUP-TFI gene mutations are associated with Bosch-Boonstra-Schaaf optic atrophy syndrome displaying symptoms of optic atrophy, intellectual disability, hypotonia, seizure, autism spectrum disorders, oromotor dysfunction, thin corpus callosum, or hearing defects, and COUP-TFII gene mutations lead to congenital heart defects and/or congenital diaphragmatic hernia with developmental delay and mental defects...
2017: Current Topics in Developmental Biology
https://www.readbyqxmd.com/read/28499234/magnetic-implants-in-the-tongue-for-assistive-technologies-tests-of-migration-oromotor-function-and-tissue-response-in-miniature-pigs
#18
Alan J Sokoloff, Zhongtao Yang, Saman Sargolzaei, Karen Strait, Andrey Krasnopeyev, Kirk A Easley, Sylvie Mimche, Maysam Ghovanloo
OBJECTIVE: Uncertain biological consequences of titanium-magnet (Ti-mag) tongue implants constrain application of the Tongue Drive System (TDS), a brain-tongue-computer interface for individuals with severe physical impairment. Here we describe oromotor function and tongue tissue response following Ti-Mag implantation and explantation in the miniature pig, an animal model with a tongue similar in size to humans. DESIGN: A 1.8×6.2mm Ti-mag tracer was implanted into the anterior tongue in five Yucatan minipigs...
September 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28484358/anthropometric-parameters-of-nutritional-status-in-children-with-cerebral-palsy
#19
Melika Melunovic, Feriha Hadzagic-Catibusic, Vildan Bilalovic, Samra Rahmanovic, Selma Dizdar
INTRODUCTION: Patients with cerebral palsy (CP), besides the basic neurological damage, are also often undernourished. Adequate nutrition for children is very important during the period of intensive growth and development, which is of particular importance in patients with CP. GOAL: To evaluate the nutritional status of patients with CP who are treated at the Pediatric Clinic, Clinical Centre of Sarajevo University and causes of malnutrition in these patients. MATERIALS AND METHODS: Eighty patients with CP underwent anthropometric assessment (body weight, body height, body mass index, head circumference, subscapular skinfold thickness, triceps skinfold thickness and mid upper arm muscle circumference)...
March 2017: Materia Socio-medica
https://www.readbyqxmd.com/read/28474131/dysphagia-in-friedreich-ataxia
#20
Megan J Keage, Martin B Delatycki, Isabelle Gupta, Louise A Corben, Adam P Vogel
The objective of the study was to comprehensively characterise dysphagia in Friedreich ataxia (FRDA) and identify predictors of penetration/aspiration during swallowing. We also investigated the psychosocial impact of dysphagia on individuals with FRDA. Sixty participants with FRDA were screened for dysphagia using a swallowing quality of life questionnaire (Swal-QOL) and case history. Individuals reporting dysphagia underwent a standardised oromotor assessment (Frenchay Dysarthria Assessment, 2, FDA-2) and videofluoroscopic study of swallowing (VFSS)...
May 4, 2017: Dysphagia
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