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https://www.readbyqxmd.com/read/28645172/the-biogenesis-pathway-of-trna-derived-pirnas-in-bombyx-germ-cells
#1
Shozo Honda, Takuya Kawamura, Phillipe Loher, Keisuke Morichika, Isidore Rigoutsos, Yohei Kirino
Transfer RNAs (tRNAs) function in translational machinery and further serves as a source of short non-coding RNAs (ncRNAs). tRNA-derived ncRNAs show differential expression profiles and play roles in many biological processes beyond translation. Molecular mechanisms that shape and regulate their expression profiles are largely unknown. Here, we report the mechanism of biogenesis for tRNA-derived Piwi-interacting RNAs (td-piRNAs) expressed in Bombyx BmN4 cells. In the cells, two cytoplasmic tRNA species, tRNAAspGUC and tRNAHisGUG, served as major sources for td-piRNAs, which were derived from the 5΄-part of the respective tRNAs...
June 22, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28645066/hydrothermal-co-carbonization-of-sewage-sludge-and-pinewood-sawdust-for-nutrient-rich-hydrochar-production-synergistic-effects-and-products-characterization
#2
Xiaojuan Zhang, Lei Zhang, Aimin Li
The aim of this study is to explore the synergistic effects of hydrothermal co-carbonization of sewage sludge and pinewood sawdust on hydrochar production. Firstly, the effects of mixing ratios on hydrothermal carbonization were investigated, and then, the hydrochar was characterized by diverse analytical techniques. The mass balance results indicated that a significant synergistic enhancement occurred in terms of the increased hydrochar yield, organic and carbon retentions. By combining sewage sludge and pinewood sawdust at the mass ratio of 1:1, 58...
June 20, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28644922/hands-support-and-postural-oscillation-during-sit-to-stand-movement-in-children-with-cerebral-palsy-and-typical-children
#3
Silvia Leticia Pavão, Nelci Adriana Cicuto Ferreira Rocha
The authors aimed to compare the weight bearing on hands during sit-to-stand (STS) movement in children with cerebral palsy (CP) and typical children (TC), verify its effect on postural oscillation, and analyze the relationship between weight bearing on hands and postural oscillation. Twenty children with CP (Gross Motor Function Classification System levels I and II) and 35 TC performed STS with and without anterior hands support. Mann-Whitney test compared weight bearing between groups. Wilcoxon test investigated differences in postural oscillation between the conditions with and without anterior hand support for both groups...
June 23, 2017: Journal of Motor Behavior
https://www.readbyqxmd.com/read/28644674/constraints-on-oscillation-parameters-from-%C3%AE-_-e-appearance-and-%C3%AE-_-%C3%AE-disappearance-in-nova
#4
P Adamson, L Aliaga, D Ambrose, N Anfimov, A Antoshkin, E Arrieta-Diaz, K Augsten, A Aurisano, C Backhouse, M Baird, B A Bambah, K Bays, B Behera, S Bending, R Bernstein, V Bhatnagar, B Bhuyan, J Bian, T Blackburn, A Bolshakova, C Bromberg, J Brown, G Brunetti, N Buchanan, A Butkevich, V Bychkov, M Campbell, E Catano-Mur, S Childress, B C Choudhary, B Chowdhury, T E Coan, J A B Coelho, M Colo, J Cooper, L Corwin, L Cremonesi, D Cronin-Hennessy, G S Davies, J P Davies, P F Derwent, R Dharmapalan, P Ding, Z Djurcic, E C Dukes, H Duyang, S Edayath, R Ehrlich, G J Feldman, M J Frank, M Gabrielyan, H R Gallagher, S Germani, T Ghosh, A Giri, R A Gomes, M C Goodman, V Grichine, R Group, D Grover, B Guo, A Habig, J Hartnell, R Hatcher, A Hatzikoutelis, K Heller, A Himmel, A Holin, J Hylen, F Jediny, M Judah, G K Kafka, D Kalra, S M S Kasahara, S Kasetti, R Keloth, L Kolupaeva, S Kotelnikov, I Kourbanis, A Kreymer, A Kumar, S Kurbanov, K Lang, W M Lee, S Lin, J Liu, M Lokajicek, J Lozier, S Luchuk, K Maan, S Magill, W A Mann, M L Marshak, K Matera, V Matveev, D P Méndez, M D Messier, H Meyer, T Miao, W H Miller, S R Mishra, R Mohanta, A Moren, L Mualem, M Muether, S Mufson, R Murphy, J Musser, J K Nelson, R Nichol, E Niner, A Norman, T Nosek, Y Oksuzian, A Olshevskiy, T Olson, J Paley, P Pandey, R B Patterson, G Pawloski, D Pershey, O Petrova, R Petti, S Phan-Budd, R K Plunkett, R Poling, B Potukuchi, C Principato, F Psihas, A Radovic, R A Rameika, B Rebel, B Reed, D Rocco, P Rojas, V Ryabov, K Sachdev, P Sail, O Samoylov, M C Sanchez, R Schroeter, J Sepulveda-Quiroz, P Shanahan, A Sheshukov, J Singh, J Singh, P Singh, V Singh, J Smolik, N Solomey, E Song, A Sousa, K Soustruznik, M Strait, L Suter, R L Talaga, M C Tamsett, P Tas, R B Thayyullathil, J Thomas, X Tian, S C Tognini, J Tripathi, A Tsaris, J Urheim, P Vahle, J Vasel, L Vinton, A Vold, T Vrba, B Wang, M Wetstein, D Whittington, S G Wojcicki, J Wolcott, N Yadav, S Yang, J Zalesak, B Zamorano, R Zwaska
Results are reported from an improved measurement of ν_{μ}→ν_{e} transitions by the NOvA experiment. Using an exposure equivalent to 6.05×10^{20} protons on target, 33 ν_{e} candidates are observed with a background of 8.2±0.8 (syst.). Combined with the latest NOvA ν_{μ} disappearance data and external constraints from reactor experiments on sin^{2}2θ_{13}, the hypothesis of inverted mass hierarchy with θ_{23} in the lower octant is disfavored at greater than 93% C.L. for all values of δ_{CP}.
June 9, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28644489/dehydrogenation-of-cyclic-amines-by-a-coordinatively-unsaturated-cp-ir-iii-phosphoramidate-complex
#5
Marcus W Drover, Laurel L Schafer, Jennifer A Love
The reaction of a Cp*Ir(iii) phosphoramidate complex with secondary amines gives amine, imine-bound Cp*Ir(iii) hydride complexes resulting from amine dehydrogenation. These well-characterized species could serve as models of relevant intermediates that have been proposed in catalytic amine dehydrogenation using related N,O-chelated Cp*Ir(iii) pyridonate complexes.
June 23, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28644092/single-and-multiple-cardiovascular-biomarkers-in-subjects-without-a-previous-cardiovascular-event
#6
Manan Pareek, Deepak L Bhatt, Muthiah Vaduganathan, Tor Biering-Sørensen, Arman Qamar, Axel Cp Diederichsen, Jacob Eifer Møller, Peter Hindersson, Margrét Leósdóttir, Martin Magnusson, Peter M Nilsson, Michael H Olsen
Aims To assess the incremental value of biomarkers, including N-terminal prohormone of brain natriuretic peptide (NT-proBNP), high-sensitivity troponin T (hs-TnT), high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), growth differentiation factor 15 (GDF-15), and procollagen type 1 N-terminal propeptide (P1NP), in predicting incident cardiovascular events and mortality among asymptomatic individuals from the general population, beyond traditional risk factors, including fasting glucose and renal function (cystatin C), medication use, and echocardiographic measures...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28644061/diffusion-weighted-magnetic-resonance-imaging-in-the-assessment-of-choroid-plexus-aging
#7
Banu Alicioglu, Guliz Yilmaz, Ozgur Tosun, Nail Bulakbasi
Recent studies have pointed out dysfunction and histopathological changes of the choroid plexuses (CPs) with aging. This paper reviews apparent diffusion coefficient (ADC) values of the CPs for age-related changes. All the brain MR images of the patients between January 2013 and June 2014 in our Radiology Department were retrospectively investigated. Patients with major cranial abnormalities (brain tumors, hyperacute or acute ischemia, developmental anomalies, hemorrhage, hydrocephaly) were excluded. Diffusion-weighted images were obtained at the parameter values of b = 1000 s/mm(2) in the axial plane...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28644031/tris-cyclopentadienyl-lanthanide-complexes-as-catalysts-for-hydroboration-reaction-toward-aldehydes-and-ketones
#8
Sufang Chen, Dandan Yan, Mingqiang Xue, Yubiao Hong, Yingming Yao, Qi Shen
It was found that homoleptic cyclopentadienyl lanthanide complexes Cp3Ln (Ln = Y (1), Yb (2), Sm (3), Nd (4), La (5), Cp = cyclopentadienyl) can be employed as excellent catalysts for the hydroboration of various aldehydes and ketones toward pinacolborane. These robust lanthanide catalysts exhibited high reactivity with low catalyst loadings (0.01-1 mol %) under mild conditions and good functional group tolerability. These complexes also demonstrated uniquely carbonyl-selective hydroboration in the presence of alkenes and alkynes...
June 23, 2017: Organic Letters
https://www.readbyqxmd.com/read/28642919/correlation-between-antioxidant-activity-and-bonding-strength-on-bleached-enamel
#9
Hellen Caroliny De Carvalho, Ricardo Danil Guiraldo, Regina Célia Poli-Frederico, Sandra Mara Maciel, Sandra Kiss Moura, Murilo Baena Lopes, Sandrine Bittencourt Berger
Objective: This study used the 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) method to evaluate the percentage of antioxidant activity (%AA) of green tea (GT) and sodium ascorbate (SA) gel in three concentrations (10%, 20% and 30%), and the influence of these concentrations on the microshear bond strength (μ-SBT) values of bleached enamel, using 10% carbamide peroxide (CP). Materials and methods: Eighty intact third molars were selected to perform the μ-SBT test, and were randomly divided into eight experimental groups: G1: positive control - no treatment; G2: negative control - bleached with CP; G3: PC +10% GT; G4: PC +20% GT; G5: PC +30% GT; G6: PC +10% SA; G7: PC +20% SA and G8: PC +30% SA...
December 2016: Acta Biomaterialia Odontologica Scandinavica
https://www.readbyqxmd.com/read/28642588/epigenetic-targeting-drugs-potentiate-chemotherapeutic-effects-in-solid-tumor-therapy
#10
Jingjing Li, Dapeng Hao, Li Wang, Haitao Wang, Yuan Wang, Zhiqiang Zhao, Peipei Li, Chuxia Deng, Li-Jun Di
Epigenetic therapy is a novel tumor therapeutic method and refers to the targeting of the aberrant epigenetic modifications presumably at cancer-related genes by chemicals which are epigenetic targeting drugs (ETDs). Not like in treating hematopoietic cancer, the clinical trials investigating the potential use of ETDs in the solid tumor is not encouraging. Instead, the curative effects of ETD delivered together with DNA targeting chemo drugs (DTDs) are quite promising according to our meta-analysis. To investigate the synergistic mechanism of ETD and DTD drug combination, the therapeutic effect was studied using both cell lines and mouse engrafted tumors...
June 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28640601/initiation-of-the-electrochemical-reduction-of-co2-by-a-singly-reduced-ruthenium-ii-bipyridine-complex
#11
Srinivasan Ramakrishnan, Christopher E D Chidsey
The one-electron reduction of [CpRu(bpy)NCCH3]PF6 (Cp = cyclopentadienyl; bpy = 2,2'-bipyridine), abbreviated as [Ru-S](+), where S = CH3CN, in CO2-saturated acetonitrile initiates a cascade of rapid electrochemical and chemical steps (ECEC) at an electrode potential of ca. 100 mV positive of the first reduction of the ruthenium complex. The overall two-electron process leads to the generation of a CO-bound ruthenium complex, [Ru-CO](+), and carbonate, as independently confirmed by NMR spectroscopy. Simulations of the cyclic voltammograms using DigiElch together with density functional theory based calculations reveal that the singly reduced ruthenium complex [Ru-S](0) binds CO2 at a rate of ca...
June 22, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28638766/metalate-mediated-functionalization-of-p4-by-trapping-anionic-cp-fe-co-2-%C3%AE-1-p4-with-lewis-acids
#12
Jaap E Borger, Maarten K Jongkind, Andreas W Ehlers, Martin Lutz, J Chris Slootweg, Koop Lammertsma
The development of selective functionalization strategies of white phosphorus (P4) is important to avoid the current chlorinated intermediates. The use of transition metals (TMs) could lead to catalytic procedures, but these are severely hampered by the high reactivity and unpredictable nature of the tetrahedron. Herein, we report selective first steps by reacting P4 with a metal anion [Cp*Fe(CO)2](-) (Cp*=C5(CH3)5), which, in the presence of bulky Lewis acids (LA; B(C6F5)3 or BPh3), leads to unique TM-substituted LA-stabilized bicyclo[1...
June 2017: ChemistryOpen
https://www.readbyqxmd.com/read/28638230/role-of-three-dimensional-endoanal-ultrasound-in-assessing-the-anal-sphincter-morphology-of-female-patients-with-chronic-proctalgia
#13
Ya-Hong Xue, Shu-Qing Ding, Yi-Jiang Ding, Li-Qun Pan
AIM: To assess the role of three-dimensional endoanal ultrasound (3D-EAUS) for morphological assessment of the anal sphincter of female patients with chronic proctalgia (CP). METHODS: In this unmatched case control study, 30 consecutive female patients with CP and 25 normal women (control group) were enrolled. 3D-EAUS was performed in all subjects. Thickness and length of internal anal sphincter (IAS), thickness of puborectalis muscle (PR), length of the external anal sphincter (EAS) plus PR, and puborectalis angle were measured and compared between the two groups...
June 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28637627/pulmonary-arterial-resistance-and-compliance-in-preterm-infants
#14
Seigo Okada, Jun Muneuchi, Yusaku Nagatomo, Mamie Watanabe, Chiaki Iida, Hiromitsu Shirouzu, Ryohei Matsuoka, Kunitaka Joo
BACKGROUND: Preterm birth is known to be associated with an increased risk of pulmonary arterial hypertension, although how preterm birth influences pulmonary hemodynamics has not been fully understood. Pulmonary arterial resistance (Rp) and compliance (Cp) are important factors to assess the pulmonary circulation. The purpose of this study is to clarify the relationship between Rp and Cp in preterm infants. METHODS: We performed cardiac catheterization in 96 infants (50 males) with ventricular septal defect, and compared pulmonary hemodynamic parameters including Rp and Cp between preterm and full-term infants...
June 16, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28637188/the-influence-of-whole-corn-feeding-method-during-the-finishing-stage-on-the-performance-of-overfed-mule-ducks
#15
J Arroyo, F Lavigne, L Fortun-Lamothe
The aim of this trial was to compare 2 feeding systems based on whole corn, a loose-mix and a free-choice feeding system, during the finishing stage on the performance of ducks. Five hundred sixteen day-old male mule ducks (Muscovy drake × Pekin duck) were divided into 3 groups that differed in the presentation of the diet they received between 58 and 88 d of age: a complete pelleted diet (Control (CON) group; AMEn 12.1 MJ/kg, CP 15.0%) containing 500 g of corn per kg; or whole corn (AMEn 13.9 MJ/kg, CP 7...
June 20, 2017: Poultry Science
https://www.readbyqxmd.com/read/28636949/cloning-expression-and-nutritional-regulation-of-the-glutamine-synthetase-gene-in-ctenopharyngodon-idellus
#16
Rong Hu, Fufa Qu, Jianzhou Tang, Qiong Zhao, Jinpeng Yan, Zhigang Zhou, Yi Zhou, Zhen Liu
Glutamine synthetase (GS) is considered a master enzyme that catalyses ATP-dependent biosynthesis of glutamine from glutamate. In the present study, the GS gene was cloned from the intestine of grass carp, (Ctenopharyngodon idellus). The full-length cDNA sequence of GS encodes a 371-amino-acid polypetide. Phylogenetic analysis of the C. idellus GS sequence reveals common carp (Cyprinus carpio) as its closest neighbor. GS mRNA was differentially expressed in different tissues, with high to low gradient expression the intestine, brain, muscle, heart, gill, liver, pituitary gland, and spleen...
June 18, 2017: Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology
https://www.readbyqxmd.com/read/28636488/workers-exposure-to-bioaerosols-from-three-different-types-of-composting-facilities
#17
Laetitia Bonifait, Geneviève Marchand, Marc Veillette, Hamza M'Bareche, Marie-Eve Dubuis, Carole Pépin, Yves Cloutier, Yves Bernard, Caroline Duchaine
Composting is a natural dynamic biological process used to valorise putrescible organic matter. The composting process can involve vigorous movements of waste material piles, which release high concentrations of bioaerosols into the surrounding environment. There is a lack of knowledge concerning the dispersal of airborne microorganisms emitted by composting plants (CP) as well as the potential occupational exposure of composting workers. The aim of this study was to investigate the workers exposure to bioaerosols during working activities in three different types of composting facilities (domestic, manure, carcass) using two different quantification methods (cultivation and qPCR) for bacteria and moulds concentrations...
June 21, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28636358/transferable-atom-centered-potentials-for-the-correction-of-basis-set-incompleteness-errors-in-density-functional-theory
#18
Alberto Otero-de-la-Roza, Gino A DiLabio
Recent progress in the accurate calculation of non-covalent interactions has enabled density-functional theory (DFT) to model systems relevant in biological and supramolecular chemistry. The application of DFT methods using atom-centered Gaussian basis sets to large systems is limited by the number of basis functions required to accurately model thermochemistry and, in particular, weak intermolecular interactions. Basis-set incompleteness error (BSIE) arising from the use of incomplete basis sets leads to erroneous intermolecular energies, bond dissociation energies, and structures...
June 21, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28636347/the-structure-and-dynamics-of-alginate-gels-crosslinked-by-polyvalent-ions-probed-via-solid-state-nmr-spectroscopy
#19
Jiří Brus, Martina Urbanová, Jiri Czernek, Miroslava Pavelkova, Katerina Kubova, Jakub Vyslouzil, Sabina Abbrent, Rafal Konefal, Jiri Horsky, David Vetchy, Jan Vysloužil, Pavel Kulich
Alginate gels are an outstanding biomaterial widely applicable in tissue engineering, medicine, and pharmacy for cell transplantation, wound healing and efficient bioactive agent delivery, respectively. This contribution provides new and comprehensive insight into the atomic-resolution structure and dynamics of polyvalent ion-crosslinked alginate gels in microbead formulations. By applying various advanced solid-state NMR (ssNMR) spectroscopy techniques, we verified the homogenous distribution of the crosslinking ions in the alginate gels and the high degree of ion exchange...
June 21, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28636336/a-mg-cp-with-in-situ-encapsulated-photochromic-guest-as-sensitive-fluorescence-sensor-for-fe-3-cr-3-ions-and-nitro-explosives
#20
Zhao-Feng Wu, Liao-Kuo Gong, Xiao-Ying Huang
Here we report a fluorescent magnesium coordination polymer (Mg-CP), namely, [CH3-dpb]2[Mg3(1,4-NDC)4(μ-H2O)2(CH3OH)(H2O)]·1.5H2O (1, 1,4-H2NDC = 1,4-naphthalene dicarboxylic acid, dpb = 1,4-bis(pyrid-4-yl)benzene). Compound 1 possesses a three-dimensional (3D) host-guest structure constructed by the 1,4-NDC linkers bridging the linear trinuclear secondary building units of [Mg3(COO)8(μ-H2O)2]. The dpb molecules were in situ reacted with CH3OH resulting in photochromic cations of [CH3-dpb](+) that acted as guests located in the channels parallel to the b-axis...
June 21, 2017: Inorganic Chemistry
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