keyword
https://read.qxmd.com/read/38656564/smarca4-deficient-undifferentiated-esophageal-carcinoma-a-clinical-case-series-and-literature-review
#1
JOURNAL ARTICLE
Faris Shweikeh, Gordon Hong, Jacob Walter, Matthew Hoscheit, Anthony Lembo, Mohamad Mouchli, Jason Lane
PURPOSE: Undifferentiated carcinoma of the esophagus (UEC) is a rare malignancy. Deficiency in SMARCA genes, critical for chromatin regulation, has been observed in cases of UEC. Research in UEC is sparse, however, and we present a case series along with a comprehensive review of the literature. CASE SERIES: Case 1 is a 49-year-old female with abdominal pain and dysphagia and esophagogastroduodenoscopy (EGD) showing a friable mass at the gastroesophageal (GE) junction...
April 24, 2024: Journal of Gastrointestinal Cancer
https://read.qxmd.com/read/38618346/expert-recommendations-on-the-diagnosis-of-eosinophilic-esophagitis-in-the-united-arab-emirates
#2
REVIEW
Sameer Al Awadhi, Mohamad Miqdady, Mohamed Abuzakouk, Osama Yousef, Christos Tzivinikos, Filippos Georgopoulos, Stuart Carr, Ahmed Sultan, Rana Bitar, Asad Izziddin Dajani, Mazen Taha, Eyad Alakrad, Ahmad Jazzar, Mohammed Banama, Khaled Bamakhrama, Nawal Alnahdi, Ahmed Ali Elghoudi, Amer Azaz, Ravi Gutta, Monica Fahmy, Boushra Raghib, Suzan Murad, Mina Abdelmallek
Eosinophilic esophagitis (EoE) is a chronic, progressive, type 2 inflammatory esophageal disease presenting as dysphagia to solid food and non-obstructive food impaction. Knowledge gaps exist in its diagnosis and management. These expert recommendations focused on the diagnosis of EoE in the United Arab Emirates. An electronic search of PubMed and Embase databases was used to gather evidence from systematic reviews, randomized controlled trials, consensus papers, and expert opinions from the last five years on the diagnosis of EoE...
March 2024: Curēus
https://read.qxmd.com/read/38596434/evolving-strategies-enhancements-in-managing-eosinophilic-esophagitis-in-pediatric-patients
#3
REVIEW
Ahmed Elghoudi, Doaa Zourob, Eman Al Atrash, Fatima Alshamsi, Manal Alkatheeri, Hassib Narchi, Rana Bitar
Eosinophilic esophagitis is a newly recognized disease first described about 50 years ago. The definition, diagnosis, and management have evolved with new published consensus guidelines and newly approved treatment available to pediatricians, enabling a better understanding of this disease and more targeted treatment for patients. We describe the definition, presentation, and diagnosis of eosinophilic esophagitis including management, challenges, and future directions in children. The definition, diagnosis, and management of eosinophilic esophagitis have evolved over the last 50 years...
March 9, 2024: World Journal of Clinical Pediatrics
https://read.qxmd.com/read/38588553/drug-delivery-systems-for-wound-healing-treatment-of-upper-airway-injury
#4
REVIEW
Denzel Ryan D Cruz, Avery Zheng, Tilahun Debele, Peter Larson, Gregory R Dion, Yoonjee C Park
INTRODUCTION: Endotracheal intubation is a common procedure to maintain an open airway with risks for traumatic injury. Pathological changes resulting from intubation can cause upper airway complications, including vocal fold scarring, laryngotracheal stenosis, and granulomas and present with symptoms such as dysphonia, dysphagia, and dyspnea. Current intubation-related laryngotracheal injury treatment approaches lack standardized guidelines, relying on individual clinician experience, and surgical and medical interventions have limitations and carry risks...
April 10, 2024: Expert Opinion on Drug Delivery
https://read.qxmd.com/read/38582536/eating-and-drinking-experience-in-patients-with-idiopathic-pulmonary-fibrosis-a-qualitative-study
#5
JOURNAL ARTICLE
Amal Ahmad Alamer, Christopher Ward, Ian Forrest, Michael Drinnan, Joanne Patterson
OBJECTIVE: To explore eating and drinking experiences of patients with idiopathic pulmonary fibrosis (IPF), the impact of any changes associated with their diagnosis and any coping mechanisms developed by patients. SETTING: Pulmonary fibrosis support groups around the UK and the regional Interstitial Lung Diseases Clinic, Newcastle upon Tyne. PARTICIPANTS: 15 patients with IPF (9 men, 6 women), median age 71 years, range (54-92) years, were interviewed...
April 5, 2024: BMJ Open
https://read.qxmd.com/read/38577756/a-plasmacytoma-of-the-lateral-pharyngeal-wall-a-diagnostic-enigma
#6
JOURNAL ARTICLE
Lefika Bathobakae, Shayee Hasan, Aneeqa Shahid, Tyler Wilkinson, Shajla Ajas, Mehandar Kumar, Sohail Qayyum, Amer Akmal
Plasmacytoma is a rare plasma cell dyscrasia that grows in bones or soft tissues such as the pharynx. Soft tissue plasmacytomas are rare, and a higher burden has been reported in the upper aero-digestive tract, often manifesting as hoarseness, dysphagia, or odynophagia. Due to their rarity, extramedullary plasmacytomas (EMPs) have unknown prognostic factors, and guidelines for optimal management are still lacking. However, radiation therapy and surgery have been used with positive outcomes. Herein, we describe a unique case of plasmacytoma of the pharyngeal tissue in a male patient with a history of HIV disease...
2024: Journal of Investigative Medicine High Impact Case Reports
https://read.qxmd.com/read/38572844/nurses-practices-in-stroke-related-dysphagia-in-low-and-middle-income-countries
#7
JOURNAL ARTICLE
Kirsten Rowe, Maria N Du Toit, Sarveshvari B Pillay, Esedra Krüger
BACKGROUND:  Nurses are often required to perform dysphagia screening prior to oral intake by people following stroke. Previous studies report limited knowledge of nurses in identifying symptoms of post-stroke dysphagia. OBJECTIVE:  To explore existing literature regarding nurses' practices and knowledge in the identification and management of post-stroke oropharyngeal dysphagia (OPD) in low- and middle income countries (LMICs). METHOD:  A scoping review was conducted according to the PRISMA-ScR guidelines...
March 28, 2024: Curationis
https://read.qxmd.com/read/38536450/surgical-management-of-chiari-ii-malformation-a-systematic-review-of-literature
#8
REVIEW
Rafael C C Vencio, Adriano M Lino-Filho, Renata C F Bonfim, Nayara M Pereira, Cilmária L Franco, Paulo Ronaldo J Ribeiro, Bárbara A Morais
PURPOSE: Chiari II malformation (CM-II) is a congenital malformation of the posterior fossa associated with myelomeningocele. Of the symptomatic patients, 10-33% require surgical treatment. To this date, there is not a consensus about the best surgical technique, and whether to do duroplasty. METHODS: A literature search of the PubMed database and crossed references was performed, per PRISMA guidelines. Data regarding demographic features, extent of cervicomedullary deformity, clinical presentation, surgical techniques, and clinical outcomes were extracted...
March 27, 2024: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://read.qxmd.com/read/38533839/dysphagia-therapy-in-adults-with-a-tracheostomy-a-scoping-review-protocol
#9
JOURNAL ARTICLE
Waiza Kadri, Rhiannon Halfpenny, Breege Whiten, Siofra Mulkerrin, Christina Smith
BACKGROUND: Swallowing impairment (dysphagia) and tracheostomy coexist. Research in this area has often provided an overview of dysphagia management as a whole, but there is limited information pertaining to specific dysphagia therapy in the tracheostomy population. The aim of this scoping review is to provide a detailed exploration of the literature with regard to dysphagia therapeutic interventions in adults with a tracheostomy. The scoping review will describe current evidence and thus facilitate future discussions to guide clinical practice...
March 27, 2024: International Journal of Language & Communication Disorders
https://read.qxmd.com/read/38523848/a-rare-case-of-persistent-multifocal-cribriform-morular-thyroid-carcinoma
#10
William Kuenstner, Po Zhao, Wen Lee, Carlos Garcia, Kenneth D Burman, Leila Shobab
BACKGROUND/OBJECTIVE: Cribriform-morular thyroid carcinoma (CMTC) was considered a variant of papillary thyroid carcinoma (PTC) but is a separate entity in the 2022 World Health Organization classification. CMTC has an association with familial adenomatous polyposis (FAP). Our objective is to report a case of CMTC who was subsequently diagnosed with FAP, to highlight these associated entities and implications for management. CASE REPORT: A 15-year-old female with a history of iron-deficiency anemia and alpha-gal syndrome presented with several years of goiter and dysphagia...
2024: AACE Clinical Case Reports
https://read.qxmd.com/read/38514228/dysphagia-and-enteral-feeding-after-stroke-in-the-rehabilitation-setting
#11
REVIEW
Robynne G Braun, Jodi Arata, Marlis Gonzalez-Fernandez
Physiatrists play a vital role in post-stroke dysphagia management not only by providing guidance on the risks, benefits, and efficacy of various treatment options but also as advocates for patients' independence and quality of life. While swallow study results are often discussed broadly by acute stroke clinicians as "pass/fail" findings, physiatrists need a more nuanced working knowledge of dysphagia diagnosis and treatment that encompasses swallow pathophysiology, targeted treatment strategies, and prognosis for recovery...
May 2024: Physical Medicine and Rehabilitation Clinics of North America
https://read.qxmd.com/read/38510594/the-efficacy-of-anchored-stand-alone-spacers-in-comparison-to-conventional-cage-and-plate-in-anterior-cervical-discectomy-and-fusion-surgery-a-meta-analysis-of-randomised-controlled-trials-for-clinical-and-radiological-outcomes
#12
REVIEW
Jake M McDonnell, Salma Youssef, Tayler D Ross, Harry Marland, Luke Turley, Gráinne Cunniffe, Stacey Darwish, Joseph S Butler
INTRODUCTION: Anterior cervical discectomy and fusion (ACDF) is commonly performed with cage and plate constructs to stabilise diseased or injured cervical segments. Despite it being a commonly performed procedure, there are notable rates of associated morbidity reported in the literature. Stand-alone spacers represent a novel form of instrumentation to conventional cage and plate constructs. RESEARCH QUESTION: Do stand-alone spacers have improved operative characteristics and postoperative outcomes in ACDF cohorts when compared to cage and plate constructs? METHODS: A systematic review and meta-analysis was conducted of PubMed/Medline, Embase and Google Scholar databases per the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes guidelines...
2024: Brain Spine
https://read.qxmd.com/read/38459985/summary-of-the-best-evidence-for-the-management-of-dysphagia-in-elderly-patients
#13
REVIEW
Mengdan Liu, Xushu Chen, Peng Ma, Min Deng
OBJECTIVE: To search for and summarize the best evidence for themanagement of elderly patients with dysphagia. METHODS: Clinical decisions, recommended practices, evidence summaries, clinical practice guidelines, expert consensus, and systematic reviews on the management of dysphagia among elderly patients were systematically reviewed from domestic and foreign guideline websites, association websites, and Chinese and English databases according to the 6S model of evidence-based resources...
March 9, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38458618/measuring-and-improving-quality-in-esophageal-care-and-swallowing-disorders
#14
JOURNAL ARTICLE
Alexander T Reddy, Joshua P Lee, David A Leiman
Evaluating clinical care through quality-related metrics is increasingly common. There are now numerous quality statements and indicators related to the medical management of benign and pre-malignant esophageal diseases. Expert consensus leveraging evidence-based recommendations from published society guidelines has been the most frequently used basis for developing esophageal quality statements. While surgical care of patients with esophageal malignancies, including squamous cell carcinoma, has also been developed, those related to benign esophageal disease now include domains of diagnosis, treatment, and monitoring for gastroesophageal reflux disease, eosinophilic esophagitis (EoE), achalasia, and Barrett's esophagus (BE)...
March 8, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38426734/tube-feeding-in-advanced-dementia-insights-from-south-african-speech-language-therapists
#15
JOURNAL ARTICLE
Danette Pullen, Bhavani S Pillay, Esedra Krüger
BACKGROUND:  Speech-language therapists (SLTs) may recommend tube feeding even with minimal research evidence of its effectiveness, and an understanding of SLTs' perceived practices is warranted. OBJECTIVES:  To qualitatively describe a sample of South African SLTs' perceived practices regarding feeding tube placement in people with advanced dementia. METHOD:  Semi-structured online interviews were conducted via Microsoft Teams...
February 12, 2024: South African Journal of Communication Disorders. die Suid-Afrikaanse Tydskrif Vir Kommunikasieafwykings
https://read.qxmd.com/read/38399485/laryngeal-paraganglioma-a-case-report
#16
Dragos Octavian Palade, Florentina Severin, Daniela Vrinceanu, Razvan Hainarosie, Alma Maniu, Huzafa Ahmed, Felicia Manole, Florin Mocanu, Catalina Voiosu
Background and Objectives : Paragangliomas of the head and neck are rare neuroendocrine tumors originating from the paraganglia, which might be sympathetic or parasympathetic. Laryngeal paragangliomas are the rarest subtype of these tumors, with only 1.41% of all paragangliomas, arising from the supraglottic or subglottic paraganglia of the larynx. The vast majority of them are benign, but there are some cases in which they turn out to be malignant, and the only way to know with certainty the difference between them is when we identify distant metastases...
January 24, 2024: Medicina
https://read.qxmd.com/read/38350785/prehabilitation-for-patients-with-cancer-undergoing-radiation-therapy-a-scoping-review
#17
JOURNAL ARTICLE
E Harris, L Marignol
AIMS: Prehabilitation is a process of identifying and assessing factors that could compromise the physical and psychological health of patients undergoing cancer treatment and implementing an intervention to combat such concerns. The use of prehabilitation in cancer surgery has yielded positive outcomes in rectal, lung and abdominal cancers. Prehabilitation strategies have potential to improve the management of patients receiving radiation therapy or chemoradiation. The aim of the present study was to map the evidence of the assessment and evaluation of prehabilitation for radiation therapy patients...
February 8, 2024: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/38322439/evaluation-and-treatment-of-dysphagia-in-public-and-private-intensive-care-units-icus-in-greece
#18
JOURNAL ARTICLE
Soultana L Papadopoulou, Evangelia Kitsanou, Ermioni Brahimi, Georgios Papathanakos, Ioannis Andrianopoulos, Stavroula J Theodorou, Vasilios Koulouras, Nafsica Ziavra
Introduction  Dysphagia is a significant but underrecognized clinical issue in the intensive care unit (ICU), and it is associated with various complications. Despite its clinical importance, there is limited research and no Greek ICU-specific guidelines for managing dysphagic patients. Additionally, only a few ICUs in Greece have dysphagia specialists, specifically speech-language pathologists (SLPs) providing their expertise. Objective  Τo identify the current practices for dysphagia management (screening, assessment, treatment) and gain insight into ICU directors' awareness/perceptions of the prevalence, complications, and risk of dysphagia...
January 2024: International Archives of Otorhinolaryngology
https://read.qxmd.com/read/38290453/a-meta-analysis-of-the-effect-of-noninvasive-brain-stimulation-on-dysphagia-in-patients-with-cerebral-stroke
#19
JOURNAL ARTICLE
Jie Guo, Chunying Chen, Fei Xie
The objective of this study is to assess the efficacy of non-invasive brain stimulation (NIBS) in preventing and treating dysphagia in patients who have experienced a cerebral stroke (CS). Both Chinese and international guidelines for the management of dysphagia resulting from CS mention various non-pharmacological treatments, such as acupuncture, mechanical myoelectric stimulation, and NIBS. However, due to limited evidence, these treatments are often suggested as measures rather than interventions. Therefore, this study assesses the impact of NIBS on the severity and improvement of dysphagia in CS patients...
January 1, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38256581/survey-on-nutrition-in-neurological-intensive-care-units-sonnic-a-cross-sectional-survey-among-german-speaking-neurointensivists-on-medical-nutritional-therapy
#20
JOURNAL ARTICLE
Leon Gehri, Moritz L Schmidbauer, Timon Putz, Luka Ratkovic, Andreas Maskos, Cedric Zeisberger, Julia Zibold, Konstantinos Dimitriadis, On Behalf Of The Ignite Study Group
Medical nutritional therapy (MNT) in neurointensive care units (NICUs) is both particularly relevant and challenging due to prolonged analgosedation, immobilization, disorders of consciousness, and the high prevalence of dysphagia. Moreover, current guideline recommendations predominantly address the general intensive care unit (ICU) population, overlooking specific characteristics of neurological patients. We, therefore, conducted a web-based, cross-sectional survey for German-speaking neurointensivists mapping the clinical practices of MNT on NICUs to identify research gaps and common grounds for future clinical trials...
January 13, 2024: Journal of Clinical Medicine
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